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Chemoselective Multicomponent One-Pot Assembly of Purine Precursors in Water

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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TNA as a Potential Alternative to Natural Nucleic Acids
inferredcites →https://doi.org/10.1002/anie.200352553openalex-snapshot
Why Does TNA Cross‐Pair More Strongly with RNA Than with DNA? An Answer From X‐ray Analysis
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Direct Assembly of Nucleoside Precursors from Two‐ and Three‐Carbon Units
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Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides and Oligodipeptoids Tagged with Triazines as Recognition Elements
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Mapping the Landscape of Potentially Primordial Informational Oligomers: Oligodipeptides Tagged with 2,4‐Disubstituted 5‐Aminopyrimidines as Recognition Elements
inferredcites →https://doi.org/10.1002/anie.200702870openalex-snapshot
Simultaneous Nucleotide Activation and Synthesis of Amino Acid Amides by a Potentially Prebiotic Multi‐Component Reaction
inferredcites →https://doi.org/10.1002/anie.201001662openalex-snapshot
Phosphate‐Mediated Interconversion of Ribo‐ and Arabino‐ Configured Prebiotic Nucleotide Intermediates
inferredcites →https://doi.org/10.1002/cbdv.200490126openalex-snapshot
Exploratory Studies to Investigate a Linked Prebiotic Origin of RNA and Coded Peptides. 3rd Communication
inferredcites →https://doi.org/10.1002/cbdv.200490167openalex-snapshot
Exploratory Studies to Investigate a Linked Prebiotic Origin of RNA and Coded Peptides. 4th Communication
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Reactions of the HCN‐Tetramer with Aldehydes
inferredcites →https://doi.org/10.1002/cbdv.200790050openalex-snapshot
On a Hypothetical Generational Relationship between HCN and Constituents of the Reductive Citric Acid Cycle
inferredcites →https://doi.org/10.1002/cbdv.200790060openalex-snapshot
RNA: Prebiotic Product, or Biotic Invention?
inferredcites →https://doi.org/10.1002/cbic.200600024openalex-snapshot
Reaction of Cytidine Nucleotides with Cyanoacetylene: Support for the Intermediacy of Nucleoside‐2′,3′‐cyclic Phosphates in the Prebiotic Synthesis of RNA
inferredcites →https://doi.org/10.1002/cbic.200700098openalex-snapshot
On the Prebiotic Synthesis of Ribonucleotides: Photoanomerisation of Cytosine Nucleosides and Nucleotides Revisited
inferredcites →https://doi.org/10.1002/cbic.200800391openalex-snapshot
Potentially Prebiotic Synthesis of Pyrimidine β‐ D ‐Ribonucleotides by Photoanomerization/Hydrolysis of α‐ D ‐Cytidine‐2′‐Phosphate
inferredcites →https://doi.org/10.1002/chem.200500139openalex-snapshot
Amino Acid Catalyzed Neogenesis of Carbohydrates: A Plausible Ancient Transformation
inferredcites →https://doi.org/10.1002/chem.200701351openalex-snapshot
The Search for a Potentially Prebiotic Synthesis of Nucleotides via Arabinose‐3‐phosphate and Its Cyanamide Derivative
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Catalysis through Induced Intramolecularity: What Can Be Learned by Mimicking Enzymes with Carbonyl Compounds that Covalently Bind Substrates?
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Chemie von a‐Aminonitrilen. Aldomerisierung von Glycolaldehyd‐phosphat zu racemischen Hexose‐2,4,6‐triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose‐2,4‐diphosphaten: rac‐Allose‐2,4,6‐triphosphat und rac‐Ribose‐2,4‐diphosphat sind die Reaktionshauptprodukte
inferredcites →https://doi.org/10.1002/hlca.200290000openalex-snapshot
The α‐ L ‐Threofuranosyl‐(3′→2′)‐oligonucleotide System (‘TNA'): Synthesis and Pairing Properties
inferredcites →https://doi.org/10.1002/jlac.18500750103openalex-snapshot
Ueber die künstliche Bildung der Milchsäure und einen neuen, dem Glycocoll homologen Körper;
inferredcites →https://doi.org/10.1002/jlac.18540910309openalex-snapshot
Ueber einen neuen aus Aldehyd ‐ Ammoniak und Blausäure entstehenden Körper
inferredcites →https://doi.org/10.1007/bf01660244openalex-snapshot
Studies in prebiotic synthesis. VII
inferredcites →https://doi.org/10.1007/bf01733902openalex-snapshot
Acceleration of HCN oligomerization by formaldehyde and related compounds: Implications for prebiotic syntheses
inferredcites →https://doi.org/10.1007/bf01808782openalex-snapshot
Prebiotic ribose synthesis: A critical analysis
inferredcites →https://doi.org/10.1016/0003-9861(62)90412-5openalex-snapshot
Synthesis of purines under possible primitive earth conditions
inferredcites →https://doi.org/10.1016/0006-291x(60)90138-8openalex-snapshot
Synthesis of adenine from ammonium cyanide
inferredcites →https://doi.org/10.1016/0040-4020(78)89038-3openalex-snapshot
Systemes de strecker et apparentes—X
inferredcites →https://doi.org/10.1016/0040-4020(80)80137-2openalex-snapshot
Systemes de strecker et apparentes—XI
inferredcites →https://doi.org/10.1016/0040-4020(80)88025-2openalex-snapshot
Systèmes de strecker et apparentes—XII
inferredcites →https://doi.org/10.1016/s0021-9258(17)43370-9openalex-snapshot
On the mechanism of the acid-catalyzed hydrolysis of uridine to uracil. Evidence for 6-hydroxy-5,6-dihydrouridine intermediates.
inferredcites →https://doi.org/10.1016/s0022-2836(67)80037-8openalex-snapshot
Mechanism of ε15 conversion studied with bacteriophage mutants
inferredcites →https://doi.org/10.1016/s0040-4020(01)99315-9openalex-snapshot
HCN and chemical evolution: The possible role of cyano compounds in prebiotic synthesis
inferredcites →https://doi.org/10.1016/s0040-4039(00)95518-7openalex-snapshot
An anomalous reaction between 2-amino-4-methyloxazole and aldehydes:Aryl and alkyl hydroxymethylation at the 5-position
inferredcites →https://doi.org/10.1016/s0065-2318(08)60250-4openalex-snapshot
Synthesis and Utilization of Formose Sugars
inferredcites →https://doi.org/10.1016/s0096-5332(08)60352-5openalex-snapshot
The Lobry De Bruyn-Alberda Van Ekenstein Transformation
inferredcites →https://doi.org/10.1021/ar50083a002openalex-snapshot
Prebiotic chemistry and nucleic acid replication
inferredcites →https://doi.org/10.1021/cb100093gopenalex-snapshot
A Stereoelectronic Effect in Prebiotic Nucleotide Synthesis
inferredcites →https://doi.org/10.1021/ja00957a050openalex-snapshot
An Unusual Photochemical Rearrangement in the Synthesis of Adenine from Hydrogen Cyanide1
inferredcites →https://doi.org/10.1021/ja00968a028openalex-snapshot
Studies in Prebiotic Synthesis. I. Aminomalononitrile and 4-Amino-5-cyanoimidazole1,2
inferredcites →https://doi.org/10.1021/ja042564zopenalex-snapshot
A Simple Glycol Nucleic Acid
inferredcites →https://doi.org/10.1021/ja0483692openalex-snapshot
Selective Derivatization and Sequestration of Ribose from a Prebiotic Mix
inferredcites →https://doi.org/10.1021/ja067371lopenalex-snapshot
Transition State Analysis of Acid-Catalyzed dAMP Hydrolysis
inferredcites →https://doi.org/10.1021/ja906557vopenalex-snapshot
Efficient and Rapid Template-Directed Nucleic Acid Copying Using 2′-Amino-2′,3′-dideoxyribonucleoside−5′-Phosphorimidazolide Monomers
inferredcites →https://doi.org/10.1021/jo00906a023openalex-snapshot
Reaction of diaminomaleonitrile with acetaldehyde
inferredcites →https://doi.org/10.1021/ol020015xopenalex-snapshot
Base-Pairing Systems Related to TNA: α-Threofuranosyl Oligonucleotides Containing Phosphoramidate Linkages1
inferredcites →https://doi.org/10.1038/199219a0openalex-snapshot
Synthesis of Complex Organic Compounds from Simple Precursors: Formation of Amino-Acids, Amino-Acid Polymers, Fatty Acids and Purines from Ammonium Cyanide
inferredcites →https://doi.org/10.1038/358203a0openalex-snapshot
Molecular replication
inferredcites →https://doi.org/10.1038/nature08013openalex-snapshot
Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions
inferredcites →https://doi.org/10.1039/b501512jopenalex-snapshot
Prebiotic carbohydrate synthesis: zinc–proline catalyzes direct aqueous aldol reactions of α-hydroxy aldehydes and ketones
inferredcites →https://doi.org/10.1055/s-1976-24127openalex-snapshot
An Improved Synthesis of 2-Amino-1,3-oxazoles under Basic Catalysis
inferredcites →https://doi.org/10.1073/pnas.92.18.8158openalex-snapshot
Rates of decomposition of ribose and other sugars: implications for chemical evolution.
inferredcites →https://doi.org/10.1093/nar/gki840openalex-snapshot
High fidelity TNA synthesis by Therminator polymerase
inferredcites →https://doi.org/10.1126/science.1092464openalex-snapshot
Borate Minerals Stabilize Ribose
inferredcites →https://doi.org/10.1126/science.1093057openalex-snapshot
Prebiotic Amino Acids as Asymmetric Catalysts
inferredcites →https://doi.org/10.1126/science.130.3370.245openalex-snapshot
Organic Compound Synthesis on the Primitive Earth
inferredcites →https://doi.org/10.1126/science.1962210openalex-snapshot
Sequence-Selective Recognition of DNA by Strand Displacement with a Thymine-Substituted Polyamide
inferredcites →https://doi.org/10.1126/science.284.5423.2118openalex-snapshot
Chemical Etiology of Nucleic Acid Structure
inferredcites →https://doi.org/10.1126/science.290.5495.1347openalex-snapshot
Chemical Etiology of Nucleic Acid Structure: The α-Threofuranosyl-(3'→2') Oligonucleotide System
inferredcites →https://doi.org/10.1248/cpb.22.2552openalex-snapshot
A new reaction of nucleotides with cyanoacetylene.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Replication Processes—From Autocatalysis to Systems Chemistry
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Brønsted Acid‐Catalyzed Four‐Component Cascade Reaction: Facile Synthesis of Hexahydroimidazo[1,2‐a]pyridines
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Three‐Component Regioselective Synthesis of Tetrahydrofuro[2,3‐d]oxazoles and Their Efficient Conversion to Oxazoles
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Syntheses and Applications of 2‐Alkynylnitriles
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Ätiologie potentiell primordialer Biomolekül‐Strukturen: Vom Vitamin B12zu den Nukleinsäuren und der Frage nach der Chemie der Entstehung des Lebens – ein Rückblick
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5(4H)‐Oxazolones as Intermediates in the Carbodiimide‐ and Cyanamide‐Promoted Peptide Activations in Aqueous Solution
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Photochemical Steps in the Prebiotic Synthesis of Purine Precursors from HCN
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Zur präbiotischen Synthese von Nukleosiden und Nukleotiden
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Etiology of Potentially Primordial Biomolecular Structures: From Vitamin B12to the Nucleic Acids and an Inquiry into the Chemistry of Life’s Origin: A Retrospective
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5(4H)‐Oxazolones as Intermediates in the Carbodiimide‐ and Cyanamide‐Promoted Peptide Activations in Aqueous Solution
inferred← citeshttps://doi.org/10.1002/anie.201303246openalex-snapshot
Photochemical Steps in the Prebiotic Synthesis of Purine Precursors from HCN
inferred← citeshttps://doi.org/10.1002/anie.201606232openalex-snapshot
Bringing Prebiotic Nucleosides and Nucleotides Down to Earth
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Dry Polymerization of 3′,5′‐Cyclic GMP to Long Strands of RNA
inferred← citeshttps://doi.org/10.1002/cbic.202300510openalex-snapshot
Prebiotic Synthesis of 3’,5’‐Cyclic Adenosine and Guanosine Monophosphates through Carbodiimide‐Assisted Cyclization
inferred← citeshttps://doi.org/10.1002/chem.201202649openalex-snapshot
Detection of Potential TNA and RNA Nucleoside Precursors in a Prebiotic Mixture by Pure Shift Diffusion‐Ordered NMR Spectroscopy
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Water‐Compatible Hydrogen‐Bond Activation: A Scalable and Organocatalytic Model for the Stereoselective Multicomponent Aza‐Henry Reaction
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Molecular Mechanism of Diaminomaleonitrile to Diaminofumaronitrile Photoisomerization: An Intermediate Step in the Prebiotic Formation of Purine Nucleobases
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Emergence of the First Catalytic Oligonucleotides in a Formamide‐Based Origin Scenario
inferred← citeshttps://doi.org/10.1002/chem.201705492openalex-snapshot
Prebiotic Chemistry of HCN Tetramerization by Automated Reaction Search
inferred← citeshttps://doi.org/10.1002/chem.202001513openalex-snapshot
Prebiotic Nucleoside Synthesis: The Selectivity of Simplicity
inferred← citeshttps://doi.org/10.1002/ejoc.201100127openalex-snapshot
Facile Three‐Component Synthesis of Macrocyclane‐Fused Pyrazolo[3,4‐b]pyridine Derivatives
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On the Origin of the Canonical Nucleobases: An Assessment of Selection Pressures across Chemical and Early Biological Evolution
inferred← citeshttps://doi.org/10.1002/slct.201702942openalex-snapshot
Convenient Synthesis of Spirooxindole‐Fused Pyrazolopyridine Derivatives
inferred← citeshttps://doi.org/10.1007/128_2013_499openalex-snapshot
Photosynthesis and Photo-Stability of Nucleic Acids in Prebiotic Extraterrestrial Environments
inferred← citeshttps://doi.org/10.1007/128_2014_569openalex-snapshot
Photoinduced Processes in Nucleic Acids
inferred← citeshttps://doi.org/10.1007/978-3-030-81039-9_7openalex-snapshot
First Steps Towards Molecular Evolution
inferred← citeshttps://doi.org/10.1007/978-3-031-34304-9_1openalex-snapshot
In the Beginning
inferred← citeshttps://doi.org/10.1007/978-3-319-93584-3_1openalex-snapshot
Nucleobases on the Primitive Earth: Their Sources and Stabilities
inferred← citeshttps://doi.org/10.1007/978-3-662-57978-7_5openalex-snapshot
Modellsynthesen von Sacchariden, Nucleobasen, Nucleosiden und Nucleotiden
inferred← citeshttps://doi.org/10.1007/978-3-662-70752-4_5openalex-snapshot
Model Syntheses of Saccharides, Nucleobases, Nucleosides, and Nucleotides
inferred← citeshttps://doi.org/10.1007/s00239-012-9536-xopenalex-snapshot
Fixation and Accumulation of Thermotolerant Catalytic Competence of a Pair of Ligase Ribozymes Through Complex Formation and Cross Ligation
inferred← citeshttps://doi.org/10.1007/s00239-020-09988-4openalex-snapshot
Cofactors are Remnants of Life’s Origin and Early Evolution
inferred← citeshttps://doi.org/10.1007/s10953-014-0162-7openalex-snapshot
Volumetric Properties of the Nucleoside Thymidine in Aqueous Solution at T = 298.15 K and p = (10 to 100) MPa
inferred← citeshttps://doi.org/10.1007/s11084-019-09582-9openalex-snapshot
Interactions of Amino Acids and Aminoxazole Derivatives: Cocrystal Formation and Prebiotic Implications Enabled by Computational Analysis
inferred← citeshttps://doi.org/10.1007/s11084-022-09624-9openalex-snapshot
On the Origin of Sugar Handedness: Facts, Hypotheses and Missing Links-A Review
inferred← citeshttps://doi.org/10.1007/s11084-023-09636-zopenalex-snapshot
Nonenzymatic Template-Directed Primer Extension Using 2′-3′ Cyclic Nucleotides Under Wet-Dry Cycles
inferred← citeshttps://doi.org/10.1007/s11084-026-09753-5openalex-snapshot
Progress and persistent questions in understanding the origin of life on Earth
inferred← citeshttps://doi.org/10.1007/s11214-019-0624-8openalex-snapshot
The Emergence of Life
inferred← citeshttps://doi.org/10.1007/s12052-012-0443-9openalex-snapshot
Prebiotic Chemistry: What We Know, What We Don't
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Prebiotic chemical refugia: multifaceted scenario for the formation of biomolecules in primitive Earth
inferred← citeshttps://doi.org/10.1016/b978-0-08-096805-6.00013-9openalex-snapshot
Six-Membered Ring Systems
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14915-7openalex-snapshot
Bicyclic 5-6 Systems: Purines
inferred← citeshttps://doi.org/10.1016/j.biochi.2012.03.015openalex-snapshot
RNA self-ligation: From oligonucleotides to full length ribozymes
inferred← citeshttps://doi.org/10.1016/j.cbpa.2014.09.015openalex-snapshot
Abiotic synthesis of RNA in water: a common goal of prebiotic chemistry and bottom-up synthetic biology
inferred← citeshttps://doi.org/10.1016/j.chempr.2017.03.001openalex-snapshot
Prebiotic Systems Chemistry: Complexity Overcoming Clutter
inferred← citeshttps://doi.org/10.1016/j.chempr.2024.05.007openalex-snapshot
Metal ions turn on a stereoselective nonenzymatic reduction of keto acids by the coenzyme NADH
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Mechanism and diastereoselectivity of the prebiotic synthesis of deoxyribonucleotide precursors C5-thiazoline: A DFT study
inferred← citeshttps://doi.org/10.1016/j.comptc.2016.01.006openalex-snapshot
Mechanistic insight into the prebiotic syntheses of pyrimidine ribonucleotide and pyrimidine deoxynucleotide precursors
inferred← citeshttps://doi.org/10.1016/j.febslet.2013.06.013openalex-snapshot
RNA self‐processing: Formation of cyclic species and concatemers from a small engineered RNA
inferred← citeshttps://doi.org/10.1016/j.ica.2018.09.041openalex-snapshot
2,6-Diaminopurine-zinc complex for primordial carbon dioxide fixation
inferred← citeshttps://doi.org/10.1016/j.jtbi.2020.110446openalex-snapshot
Emergence of ribozyme and tRNA-like structures from mineral-rich muddy pools on prebiotic earth
inferred← citeshttps://doi.org/10.1016/j.molstruc.2017.08.087openalex-snapshot
Study of an efficient conversion of 1,3-dimethyl-5-(Arylazo)-6-Amino-Uracils to 1,3-dimethyl-8-(Aryl)-Azapurin-2,6-Diones
inferred← citeshttps://doi.org/10.1016/j.plrev.2011.12.015openalex-snapshot
Is formamide natureʼs choice to create life?
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Multicomponent synthesis of allomaltol containing 2-aminooxazoles and acid-catalyzed recyclization into substituted furo[3,2-b]pyrans
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An efficient and highly selective approach for the construction of novel dispiro heterocycles in guanidine-based task-specific [TMG][Ac] ionic liquid
inferred← citeshttps://doi.org/10.1021/acs.chemrev.0c00191openalex-snapshot
Nonenzymatic Metabolic Reactions and Life’s Origins
inferred← citeshttps://doi.org/10.1021/acs.chemrev.9b00546openalex-snapshot
Chemistry of Abiotic Nucleotide Synthesis
inferred← citeshttps://doi.org/10.1021/acs.orglett.0c01731openalex-snapshot
Diastereoselective and Reversed Regioselective Annulations of N-Alkyl Anilines to Julolidines and Lilolidines
inferred← citeshttps://doi.org/10.1021/acscentsci.7b00085openalex-snapshot
Chiral Sugars Drive Enantioenrichment in Prebiotic Amino Acid Synthesis
inferred← citeshttps://doi.org/10.1021/ar2002683openalex-snapshot
From Prelife to Life: How Chemical Kinetics Become Evolutionary Dynamics
inferred← citeshttps://doi.org/10.1021/ar200316nopenalex-snapshot
On the Origin of Single Chirality of Amino Acids and Sugars in Biogenesis
inferred← citeshttps://doi.org/10.1021/ar300222jopenalex-snapshot
Whence Flavins? Redox-Active Ribonucleotides Link Metabolism and Genome Repair to the RNA World
inferred← citeshttps://doi.org/10.1021/cr2004844openalex-snapshot
Prebiotic Systems Chemistry: New Perspectives for the Origins of Life
inferred← citeshttps://doi.org/10.1021/ct401004ropenalex-snapshot
Complex Chemical Reaction Networks from Heuristics-Aided Quantum Chemistry
inferred← citeshttps://doi.org/10.1021/ja2072252openalex-snapshot
A Prebiotic Role for 8-Oxoguanosine as a Flavin Mimic in Pyrimidine Dimer Photorepair
inferred← citeshttps://doi.org/10.1021/ja306176nopenalex-snapshot
Multicomponent Assembly of Proposed DNA Precursors in Water
inferred← citeshttps://doi.org/10.1021/jacs.5c09581openalex-snapshot
Autocatalytic Reaction between HCN and Cysteamine Produces Hydrophobic, Catalytic, Liquid Compartments
inferred← citeshttps://doi.org/10.1021/je500458eopenalex-snapshot
Volumetric Properties at High Pressures of the Nucleosides Inosine, 2′-Deoxyinosine, and 2′-Deoxyguanosine and the Volumetric Properties of Guanosine Derived Using Group Additivity Methods
inferred← citeshttps://doi.org/10.1021/jp209886bopenalex-snapshot
Formamide-Based Prebiotic Synthesis of Nucleobases: A Kinetically Accessible Reaction Route
inferred← citeshttps://doi.org/10.1021/jp411415popenalex-snapshot
High-Energy Chemistry of Formamide: A Simpler Way for Nucleobase Formation
inferred← citeshttps://doi.org/10.1038/nchem.1108openalex-snapshot
A route to enantiopure RNA precursors from nearly racemic starting materials
inferred← citeshttps://doi.org/10.1038/nchem.1127openalex-snapshot
Self-reproduction of supramolecular giant vesicles combined with the amplification of encapsulated DNA
inferred← citeshttps://doi.org/10.1038/nchem.1623openalex-snapshot
Functional RNAs exhibit tolerance for non-heritable 2′–5′ versus 3′–5′ backbone heterogeneity
inferred← citeshttps://doi.org/10.1038/nchem.2155openalex-snapshot
Heat flux across an open pore enables the continuous replication and selection of oligonucleotides towards increasing length
inferred← citeshttps://doi.org/10.1038/nchem.2551openalex-snapshot
Oligoarginine peptides slow strand annealing and assist non-enzymatic RNA replication
inferred← citeshttps://doi.org/10.1038/nchem.2703openalex-snapshot
Prebiotic selection and assembly of proteinogenic amino acids and natural nucleotides from complex mixtures
inferred← citeshttps://doi.org/10.1038/ncomms15270openalex-snapshot
Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides
inferred← citeshttps://doi.org/10.1038/s41467-017-02065-3openalex-snapshot
Proton gradients and pH oscillations emerge from heat flow at the microscale
inferred← citeshttps://doi.org/10.1038/s41467-021-23206-9openalex-snapshot
Autocatalytic and oscillatory reaction networks that form guanidines and products of their cyclization
inferred← citeshttps://doi.org/10.1038/s41557-022-00982-5openalex-snapshot
Prebiotic synthesis and triphosphorylation of 3′-amino-TNA nucleosides
inferred← citeshttps://doi.org/10.1038/s41598-018-33157-9openalex-snapshot
Templated replication (or lack thereof) under prebiotically pertinent conditions
inferred← citeshttps://doi.org/10.1039/9781839164798-00077openalex-snapshot
First Steps of Prebiotic Chemistry Catalyzed by Minerals and Metals
inferred← citeshttps://doi.org/10.1039/9781839164798-00347openalex-snapshot
Investigating Prebiotic Protocells for an Understanding of the Origin of Life: A Comprehensive Perspective Combining the Chemical, Evolutionary and Historical Aspects
inferred← citeshttps://doi.org/10.1039/b822061copenalex-snapshot
Bioinspired organic chemistry
inferred← citeshttps://doi.org/10.1039/c1oc90018hopenalex-snapshot
Bioinspired organic chemistry
inferred← citeshttps://doi.org/10.1039/c2cs35051copenalex-snapshot
Chirality, photochemistry and the detection of amino acids in interstellar ice analogues and comets
inferred← citeshttps://doi.org/10.1039/c3cp44156copenalex-snapshot
Structural and energetic factors controlling the enantioselectivity of dinucleotide formation under prebiotic conditions
inferred← citeshttps://doi.org/10.1039/c3gc37128jopenalex-snapshot
Chemodivergent, multicomponent domino reactions in aqueous media: l-proline-catalyzed assembly of densely functionalized 4H-pyrano[2,3-c]pyrazoles and bispyrazolyl propanoates from simple, acyclic starting materials
inferred← citeshttps://doi.org/10.1039/c3ra44600jopenalex-snapshot
Deep eutectic solvent promoted efficient and environmentally benign four-component domino protocol for synthesis of spirooxindoles
inferred← citeshttps://doi.org/10.1039/c3ra44776fopenalex-snapshot
H-Bond activated glycosylation of nucleobases: implications for prebiotic nucleoside synthesis
inferred← citeshttps://doi.org/10.1039/c4cp02074jopenalex-snapshot
Solvent effects on the photochemistry of 4-aminoimidazole-5-carbonitrile, a prebiotically plausible precursor of purines
inferred← citeshttps://doi.org/10.1039/c4gc01431fopenalex-snapshot
Catalyst-free one-pot four-component domino reactions in water–PEG-400: highly efficient and convergent approach to thiazoloquinoline scaffolds
inferred← citeshttps://doi.org/10.1039/c4ra00093eopenalex-snapshot
FeCl 3 ·6H 2 O catalyzed aqueous media domino synthesis of 5-monoalkylbarbiturates: water as both reactant and solvent
inferred← citeshttps://doi.org/10.1039/c5ob00210aopenalex-snapshot
One-step protecting-group-free synthesis of azepinomycin in water
inferred← citeshttps://doi.org/10.1039/c5ra07642kopenalex-snapshot
Four-component reaction between naphthols, substituted β-nitrostyrenes, substituted benzaldehydes and ammonium acetate in water–PEG-400: an approach to construct polysubstituted naphthofuranamines
inferred← citeshttps://doi.org/10.1039/c6cp00670aopenalex-snapshot
Prebiotic synthesis of nucleic acids and their building blocks at the atomic level – merging models and mechanisms from advanced computations and experiments
inferred← citeshttps://doi.org/10.1039/c6cp07993hopenalex-snapshot
Stability of 2′,3′ and 3′,5′ cyclic nucleotides in formamide and in water: a theoretical insight into the factors controlling the accumulation of nucleic acid building blocks in a prebiotic pool
inferred← citeshttps://doi.org/10.1039/c6cp08068eopenalex-snapshot
A theoretical insight into the formation mechanisms of C/N-ribonucleosides with pyrimidine and ribose
inferred← citeshttps://doi.org/10.1039/c6ra21376fopenalex-snapshot
Organocatalytic domino Knöevenagel–Michael reaction in water for the regioselective synthesis of benzo[4,5]imidazo[1,2-a]pyrimidines and pyrido[2,3-d]pyrimidin-2-amines
inferred← citeshttps://doi.org/10.1039/c7cc00693dopenalex-snapshot
A new and potentially prebiotic α-cytidine derivative
inferred← citeshttps://doi.org/10.1039/c8cc07343kopenalex-snapshot
Photostability of oxazoline RNA-precursors in UV-rich prebiotic environments
inferred← citeshttps://doi.org/10.1039/c8fd00086gopenalex-snapshot
Electron-driven proton transfer enables nonradiative photodeactivation in microhydrated 2-aminoimidazole
inferred← citeshttps://doi.org/10.1039/d4nj00995aopenalex-snapshot
Oxazoline amino acid bioconjugates: one-pot synthesis and analysis of supramolecular interactions
inferred← citeshttps://doi.org/10.1051/0004-6361/202243696openalex-snapshot
Decoding millimetre-wave spectra of 2-iminopropanenitrile, a candidate for astronomical observations
inferred← citeshttps://doi.org/10.1051/bioconf/20140204001openalex-snapshot
Systems chemistry of α-amino acids and peptides
inferred← citeshttps://doi.org/10.1073/pnas.1312329110openalex-snapshot
Fast and accurate nonenzymatic copying of an RNA-like synthetic genetic polymer
inferred← citeshttps://doi.org/10.1073/pnas.1715433114openalex-snapshot
Darwin’s prescient guess
inferred← citeshttps://doi.org/10.1073/pnas.1721296115openalex-snapshot
Constraining the climate and ocean pH of the early Earth with a geological carbon cycle model
inferred← citeshttps://doi.org/10.1073/pnas.1721369115openalex-snapshot
Backbone-free duplex-stacked monomer nucleic acids exhibiting Watson–Crick selectivity
inferred← citeshttps://doi.org/10.1080/00397911.2020.1737129openalex-snapshot
PEG-assisted one-pot three-component synthesis of 1,3-oxazino quinoline and chromeno 1,3-oxazin derivatives under catalyst free condition
inferred← citeshttps://doi.org/10.1088/1361-6633/aa7804openalex-snapshot
Origins of life: a problem for physics, a key issues review
inferred← citeshttps://doi.org/10.1089/ast.2011.0789openalex-snapshot
Refining the Genetic Alphabet: A Late-Period Selection Pressure?
inferred← citeshttps://doi.org/10.1089/ast.2012.0924openalex-snapshot
Emergence of Life from Multicomponent Mixtures of Chemicals: The Case for Experiments with Cycling Physicochemical Gradients
inferred← citeshttps://doi.org/10.1089/ast.2013.1057openalex-snapshot
Evaluating the Plausibility of Prebiotic Multistage Syntheses
inferred← citeshttps://doi.org/10.1089/ast.2014.1213openalex-snapshot
227 Views of RNA: Is RNA Unique in Its Chemical Isomer Space?
inferred← citeshttps://doi.org/10.1089/ast.2018.1929openalex-snapshot
Nucleic Acid Extraction and Sequencing from Low-Biomass Synthetic Mars Analog Soils for In Situ Life Detection
inferred← citeshttps://doi.org/10.1089/ast.2023.0007openalex-snapshot
The Origin and Early Evolution of Life: Homochirality Emergence in Prebiotic Environments
inferred← citeshttps://doi.org/10.1093/molbev/msx265openalex-snapshot
Interdependence, Reflexivity, Fidelity, Impedance Matching, and the Evolution of Genetic Coding
inferred← citeshttps://doi.org/10.1093/nar/gkt1405openalex-snapshot
A ribozyme that triphosphorylates RNA 5′-hydroxyl groups
inferred← citeshttps://doi.org/10.1093/nar/gkz1125openalex-snapshot
Regioselective formation of RNA strands in the absence of magnesium ions
inferred← citeshttps://doi.org/10.1098/rspb.2021.2098openalex-snapshot
Evolution towards increasing complexity through functional diversification in a protocell model of the RNA world
inferred← citeshttps://doi.org/10.1098/rstb.2016.0419openalex-snapshot
The origin of heredity in protocells
inferred← citeshttps://doi.org/10.1101/2022.07.11.499554openalex-snapshot
Nonenzymatic template-directed replication using 2′-3′ cyclic nucleotides under wet-dry cycles
inferred← citeshttps://doi.org/10.1101/cshperspect.a034801openalex-snapshot
Protocells and RNA Self-Replication
inferred← citeshttps://doi.org/10.1134/s0016702914130084openalex-snapshot
Modeling of abiotic ATP synthesis in the context of problems of early biosphere evolution
inferred← citeshttps://doi.org/10.1177/15311074261428661openalex-snapshot
A Multilamellar Lipid–Polymer Progenitor Can Promote the Assembly of Improbable Functional Polymer Complexes at Life’s Origins
inferred← citeshttps://doi.org/10.1177/15311074261454245openalex-snapshot
Terrestrial Abiotic Synthesis of Simple Precursor Molecules Starting from Two Approaches: The Universality of Carbon Reduction
inferred← citeshttps://doi.org/10.1186/1759-2208-3-2openalex-snapshot
The eightfold path to non-enzymatic RNA replication
inferred← citeshttps://doi.org/10.1186/s12862-019-1412-5openalex-snapshot
From molecular to cellular form: modeling the first major transition during the arising of life
inferred← citeshttps://doi.org/10.1186/s13062-015-0049-6openalex-snapshot
In silico ribozyme evolution in a metabolically coupled RNA population
inferred← citeshttps://doi.org/10.1261/rna.074302.119openalex-snapshot
Geochemical influences on nonenzymatic oligomerization of prebiotically relevant cyclic nucleotides
inferred← citeshttps://doi.org/10.1371/journal.pone.0020931openalex-snapshot
The Evolution of Enzyme Specificity in the Metabolic Replicator Model of Prebiotic Evolution
inferred← citeshttps://doi.org/10.2174/13852728113179990090openalex-snapshot
Michael Addition-initiated Sequential Reactions from 1,3-dicarbonyls for the Synthesis of Polycyclic Heterocycles
inferred← citeshttps://doi.org/10.2478/dos-2014-0002openalex-snapshot
Diversity oriented, efficient and sustainable synthetic protocol for the synthesis of structurally diverse drug-like complex heterocycles, incorporating privileged heterocyclic systems
inferred← citeshttps://doi.org/10.3390/ijms232415756openalex-snapshot
Prebiotic Assembly of Cloverleaf tRNA, Its Aminoacylation and the Origin of Coding, Inferred from Acceptor Stem Coding-Triplets
inferred← citeshttps://doi.org/10.3390/life11080800openalex-snapshot
Questions and Answers Related to the Prebiotic Production of Oligonucleotide Sequences from 3′,5′ Cyclic Nucleotide Precursors
inferred← citeshttps://doi.org/10.3390/life11121343openalex-snapshot
Computational Analysis of a Prebiotic Amino Acid Synthesis with Reference to Extant Codon–Amino Acid Relationships
inferred← citeshttps://doi.org/10.3390/life14020277openalex-snapshot
Three Biopolymers and Origin of Life Scenarios
inferred← citeshttps://doi.org/10.3390/life16081287openalex-snapshot
Exonuclease Ribozyme Encoded in a Circular Genome: On the Initiation of the RNA World
inferred← citeshttps://doi.org/10.3390/life4040598openalex-snapshot
Synergism and Mutualism in Non-Enzymatic RNA Polymerization
inferred← citeshttps://doi.org/10.3390/life5010065openalex-snapshot
Characterization of RNA-Like Oligomers from Lipid-Assisted Nonenzymatic Synthesis: Implications for Origin of Informational Molecules on Early Earth
inferred← citeshttps://doi.org/10.3390/life5021445openalex-snapshot
The Routes of Emergence of Life from LUCA during the RNA and Viral World: A Conspectus
inferred← citeshttps://doi.org/10.3390/life7040049openalex-snapshot
What Does “the RNA World” Mean to “the Origin of Life”?
inferred← citeshttps://doi.org/10.3390/life8040057openalex-snapshot
Exploring the Emergence of RNA Nucleosides and Nucleotides on the Early Earth
inferred← citeshttps://doi.org/10.3390/life9010019openalex-snapshot
Making Molecules with Clay: Layered Double Hydroxides, Pentopyranose Nucleic Acids and the Origin of Life
inferred← citeshttps://doi.org/10.3847/1538-4357/aac169openalex-snapshot
The Distribution and Excitation of CH3CN in a Solar Nebula Analog
inferred← citeshttps://doi.org/10.48550/arxiv.1705.08073openalex-snapshot
Origins of Life: A Problem for Physics
inferred← citeshttps://doi.org/10.5282/edoc.17986openalex-snapshot
Untersuchungen zur präbiotischen Entstehung von Purin-Nukleosiden und Totalsynthese von natürlichen 7-Desaza-RNA-Modifikationen
inferred← citeshttps://doi.org/10.70675/4b409df6z06e4z4549za275zc251102dcff9openalex-snapshot
Nonenzymatic analog of pyrimidine ribonucleotide biosynthesis
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