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Efficacy of Base-Modification on Target Binding of Small Molecule DNA Aptamers

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/1521-3773(20011105)40:21<3990::aid-anie3990>3.0.co;2-oopenalex-snapshot
Functionalized DNA: A New Replicable Biopolymer We thank Dr. Andreas Marx, University of Bonn, for helpful advice and discussions. This work was supported by the Fonds der Chemischen Industrie, the Karl-Ziegler Stiftung, and the Deutsche Forschungsgemeinschaft.
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Isolation of RNA Aptamers for Biological Cofactors by In Vitro Selection
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An Aptamer–Doxorubicin Physical Conjugate as a Novel Targeted Drug‐Delivery Platform
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Self‐Assembly of a Bifunctional DNA Carrier for Drug Delivery
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Self‐Assembled Aptamer‐Based Drug Carriers for Bispecific Cytotoxicity to Cancer Cells
inferredcites →https://doi.org/10.1002/chem.200305624openalex-snapshot
Multiple Binding Modes of the Camptothecin Family to DNA Oligomers
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Molecular Recognition of Small‐Cell Lung Cancer Cells Using Aptamers
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Identification of two novel arginine binding DNAs.
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Label‐free determination of protein–ligand binding constants using mass spectrometry and validation using surface plasmon resonance and isothermal titration calorimetry
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Oligonucleotide inhibitors of human thrombin that bind distinct epitopes
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Crystal structure of DNA polymerase from hyperthermophilic archaeon Pyrococcus kodakaraensis KOD111Edited by R. Huber
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Quantitative Analysis of Small Molecule–Nucleic Acid Interactions with a Biosensor Surface and Surface Plasmon Resonance Detection
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Nuclease-resistant nucleic acid ligands to vascular permeability factor/vascular endothelial growth factor
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Analyzing a kinetic titration series using affinity biosensors
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A DNA aptamer with high affinity and specificity for therapeutic anthracyclines
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Aptamer-conjugated nanomaterials and their applications
inferredcites →https://doi.org/10.1016/j.biochi.2011.05.022openalex-snapshot
Nucleic acids targeted to drugs: SELEX against a quadruplex ligand
inferredcites →https://doi.org/10.1016/j.bmc.2003.12.009openalex-snapshot
Sialyllactose-binding modified DNA aptamer bearing additional functionality by SELEX
inferredcites →https://doi.org/10.1016/j.bmcl.2010.02.109openalex-snapshot
In vitro selection of a photoresponsive RNA aptamer to hemin
inferredcites →https://doi.org/10.1016/j.cbpa.2008.06.028openalex-snapshot
SELEX with modified nucleotides
inferredcites →https://doi.org/10.1016/j.cbpa.2012.03.016openalex-snapshot
DNA aptamer functionalized nanomaterials for intracellular analysis, cancer cell imaging and drug delivery
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Biosensor-surface plasmon resonance: Quantitative analysis of small molecule–nucleic acid interactions
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The relevance of tumour pH to the treatment of malignant disease
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In vitro selection of phosphorothiolated aptamers
inferredcites →https://doi.org/10.1016/s0960-894x(99)00600-9openalex-snapshot
Aptamers containing thymidine 3′-O-phosphorodithioates: Synthesis and binding to nuclear factor-κB
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Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells
inferredcites →https://doi.org/10.1021/bc0001342openalex-snapshot
In Vitro Selection of RNA Aptamers Carrying Multiple Biotin Groups in the Side Chains
inferredcites →https://doi.org/10.1021/bi00002a033openalex-snapshot
A DNA Aptamer That Binds Adenosine and ATP
inferredcites →https://doi.org/10.1021/bi027354iopenalex-snapshot
A Novel, Modification-Dependent ATP-Binding Aptamer Selected from an RNA Library Incorporating a Cationic Functionality
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Out-of-Shape DNA Minor Groove Binders: Induced Fit Interactions of Heterocyclic Dications with the DNA Minor Groove
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DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
inferredcites →https://doi.org/10.1021/ja049171kopenalex-snapshot
A Small Aptamer with Strong and Specific Recognition of the Triphosphate of ATP
inferredcites →https://doi.org/10.1021/ja051725bopenalex-snapshot
A Versatile Toolbox for Variable DNA Functionalization at High Density
inferredcites →https://doi.org/10.1021/ja067098nopenalex-snapshot
Modified DNA Aptamer That Binds the ( R )-Isomer of a Thalidomide Derivative with High Enantioselectivity
inferredcites →https://doi.org/10.1021/ja075953copenalex-snapshot
Amplification of 4‘-ThioDNA in the Presence of 4‘-Thio-dTTP and 4‘-Thio-dCTP, and 4‘-ThioDNA-Directed Transcription in Vitro and in Mammalian Cells
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Water-Mediated Binding of Agents that Target the DNA Minor Groove
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pH-Induced Intramolecular Folding Dynamics of i-Motif DNA
inferredcites →https://doi.org/10.1021/ja801510dopenalex-snapshot
Selecting Aptamers for a Glycoprotein through the Incorporation of the Boronic Acid Moiety
inferredcites →https://doi.org/10.1021/ja900744eopenalex-snapshot
Stabilization of Three-Way Junctions of DNA under Molecular Crowding Conditions
inferredcites →https://doi.org/10.1021/ja908035gopenalex-snapshot
Expanding the Chemistry of DNA for in Vitro Selection
inferredcites →https://doi.org/10.1021/ja9816436openalex-snapshot
Quantitative Analysis of Receptors for Adenosine Nucleotides Obtained via In Vitro Selection from a Library Incorporating a Cationic Nucleotide Analog
inferredcites →https://doi.org/10.1021/jp308402vopenalex-snapshot
Thermodynamics-Hydration Relationships within Loops That Affect G-Quadruplexes under Molecular Crowding Conditions
inferredcites →https://doi.org/10.1038/346818a0openalex-snapshot
In vitro selection of RNA molecules that bind specific ligands
inferredcites →https://doi.org/10.1038/364550a0openalex-snapshot
An RNA motif that binds ATP
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A proximity-based programmable DNA nanoscale assembly line
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Cancer immunotherapy comes of age
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Topoisomerase I inhibitors: camptothecins and beyond
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Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
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Mode of binding of camptothecins to double helix oligonucleotidesElectronic supplementary information (ESI) available: Chemical shift values, inter-proton distances obtained from MD simulations of CAP model for the complex d(CGTATACG)2/Cpt 6 and molecular dynamics figures. See…
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Nucleic acid amphiphiles: synthesis and self-assembled nanostructures
inferredcites →https://doi.org/10.1073/pnas.0602615103openalex-snapshot
Aptamers evolved from live cells as effective molecular probes for cancer study
inferredcites →https://doi.org/10.1073/pnas.0704211104openalex-snapshot
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
inferredcites →https://doi.org/10.1073/pnas.182095699openalex-snapshot
Isolation of high-affinity GTP aptamers from partially structured RNA libraries
inferredcites →https://doi.org/10.1073/pnas.95.4.1460openalex-snapshot
A unified view of polymer, dumbbell, and oligonucleotide DNA nearest-neighbor thermodynamics
inferredcites →https://doi.org/10.1074/jbc.m110181200openalex-snapshot
Design and Optimization of Camptothecin Conjugates of Triple Helix-forming Oligonucleotides for Sequence-specific DNA Cleavage by Topoisomerase I
inferredcites →https://doi.org/10.1093/nar/22.24.5229openalex-snapshot
Modified RNA sequence pools forin vitroselection
inferredcites →https://doi.org/10.1093/nar/24.6.1029openalex-snapshot
RNA aptamers that bind L-arginine with sub-micromolar dissociation constants and high enantioselectivity
inferredcites →https://doi.org/10.1093/nar/26.17.3915openalex-snapshot
Staining of cell surface human CD4 with 2'-F-pyrimidine-containing RNA aptamers for flow cytometry
inferredcites →https://doi.org/10.1093/nar/30.6.1401openalex-snapshot
Boron-containing aptamers to ATP
inferredcites →https://doi.org/10.1093/nar/gkg595openalex-snapshot
Mfold web server for nucleic acid folding and hybridization prediction
inferredcites →https://doi.org/10.1093/nar/gkl637openalex-snapshot
Systematic characterization of 2′-deoxynucleoside- 5′-triphosphate analogs as substrates for DNA polymerases by polymerase chain reaction and kinetic studies on enzymatic production of modified DNA
inferredcites →https://doi.org/10.1093/nar/gkn404openalex-snapshot
Systematic analysis of enzymatic DNA polymerization using oligo-DNA templates and triphosphate analogs involving 2′,4′-bridged nucleosides
inferredcites →https://doi.org/10.1093/nar/gkq823openalex-snapshot
Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer
inferredcites →https://doi.org/10.1093/nar/gkr522openalex-snapshot
Thrombin–aptamer recognition: a revealed ambiguity
inferredcites →https://doi.org/10.1126/science.1217622openalex-snapshot
Synthetic Genetic Polymers Capable of Heredity and Evolution
inferredcites →https://doi.org/10.1126/science.2200121openalex-snapshot
Systematic Evolution of Ligands by Exponential Enrichment: RNA Ligands to Bacteriophage T4 DNA Polymerase
inferredcites →https://doi.org/10.1128/aem.63.11.4504-4510.1997openalex-snapshot
Characterization of DNA polymerase from Pyrococcus sp. strain KOD1 and its application to PCR
inferredcites →https://doi.org/10.1146/annurev-biochem-060308-102244openalex-snapshot
Nanomaterials Based on DNA
inferredcites →https://doi.org/10.1155/2012/748913openalex-snapshot
Challenges and Opportunities for Small Molecule Aptamer Development
inferredcites →https://doi.org/10.1261/rna.2251306openalex-snapshot
Solution structure of an informationally complex high-affinity RNA aptamer to GTP
inferredcites →https://doi.org/10.1371/journal.pone.0015004openalex-snapshot
Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery
inferredcites →https://doi.org/10.2116/analsci.24.167openalex-snapshot
Arginine-modified DNA Aptamers That Show Enantioselective Recognition of the Dicarboxylic Acid Moiety of Glutamic Acid
inferredcites →https://doi.org/10.2174/138161210790963788openalex-snapshot
Peptidic Tumor Targeting Agents: The Road from Phage Display Peptide Selections to Clinical Applications
inferredcites →https://doi.org/10.2174/138161212799958477openalex-snapshot
G-quadruplex DNA Aptamers and their Ligands: Structure, Function and Application
inferredcites →https://doi.org/10.3109/10409238.2011.614592openalex-snapshot
Chimeric aptamers in cancer cell-targeted drug delivery
inferredcites →https://doi.org/10.4161/adna.19272openalex-snapshot
Enzymatic synthesis of DNA strands containing α-L-LNA (α-L-configured locked nucleic acid) thymine nucleotides

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Synthesis of Purine Conjugates with Bis-Carboranyl Derivatives of (S)-Lysine or (S)-Glutamic Acid
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Synthesis of Purine Conjugates with Bis-Carboranyl Derivatives of (S)-Lysine or (S)-Glutamic Acid
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Nucleic Acid‐Templated Synthesis of Sequence‐Defined Synthetic Polymers
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InChemicoModification of Nucleotides for Better Recognition
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Polymerase Synthesis of DNAs Bearing Vinyl Groups in the Major Groove and their Cleavage by Restriction Endonucleases
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Polymerase Synthesis and Restriction Enzyme Cleavage of DNA Containing 7‐Substituted 7‐Deazaguanine Nucleobases
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Polymerase Synthesis of Hypermodified DNA Displaying a Combination of Thiol, Hydroxyl, Carboxylate, and Imidazole Functional Groups in the Major Groove
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Aptamer‐Based Universal Fluorometric Sensors Based on Allosteric Modulation of RNA–Peptide Interactions
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Selection of Natural and Base‐Modified DNA Aptamers for a Camptothecin Derivative
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Polymerase Synthesis of Base-Modified DNA
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Polymerase Reactions that Involve Modified Nucleotides
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Progress in Chemically Modified Nucleic Acid Aptamers
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Lengthening the aptamer to hybridize with a stem-loop DNA assistant probe for the electrochemical detection of kanamycin with improved sensitivity
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The Toolbox for Modified Aptamers
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Clinical use and future perspective of aptamers
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A high affinity modified DNA aptamer containing base-appended bases for human β-defensin
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Recent advancements in aptamers as promising nanotool for therapeutic and diagnostic applications
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Aptamer chemistry
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Emerging biotechnologies for evaluating disruption of stress, sleep, and circadian rhythm mechanism using aptamer-based detection of salivary biomarkers
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Polymerase-mediated high-density incorporation of amphiphilic functionalities into DNA: Enhancement of nuclease resistance and stability in human serum
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Selective incorporation of foreign functionality into fibrin gels through a chemically modified DNA aptamer
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Towards applications of synthetic genetic polymers in diagnosis and therapy
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Aptamers capable of simultaneously identifying multiple targets and corresponding applications in medical diagnosis—A review
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Quantum chemical calculation of free radical substitution reaction mechanism of camptothecin
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Is less more? Lessons from aptamer selection strategies
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A fluorescent assay for sensitive detection of kanamycin by split aptamers and DNA-based copper/silver nanoclusters
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A signal-on fluorescent aptasensor based on single-stranded DNA-sensitized luminescence of terbium (III) for label-free detection of breast cancer cells
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Hemicyanine-linked pyrimidine mimics as solvatochromic fluorophores with visible excitation wavelengths
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Synthesis of purine conjugates with bis-carboranyl derivatives of (S)-lysine or (S)-glutamic acid
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DNA aptamer selection in methanolic media: Adenine–aptamer as proof-of-concept
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Enhancing the Analytical Performance of Electrochemical RNA Aptamer-Based Sensors for Sensitive Detection of Aminoglycoside Antibiotics
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Isolation of Natural DNA Aptamers for Challenging Small-Molecule Targets, Cannabinoids
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Antibody-Mediated Small Molecule Detection Using Programmable DNA-Switches
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Aptamer Recognition of Multiplexed Small-Molecule-Functionalized Substrates
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Terminal Alkyne-Modified DNA Aptamers with Enhanced Protein Binding Affinities
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A Simple Molecular Rotor for Defining Nucleoside Environment within a DNA Aptamer–Protein Complex
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Chemical Amplification-Enabled Topological Modification of Nucleic Acid Aptamers for Enhanced Cancer-Targeted Theranostics
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DNA Aptamer–Target Binding Motif Revealed Using a Fluorescent Guanine Probe: Implications for Food Toxin Detection
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Synthesis of Base-Modified 2′-Deoxyribonucleoside Triphosphates and Their Use in Enzymatic Synthesis of Modified DNA for Applications in Bioanalysis and Chemical Biology
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Recognition and sensing of low-epitope targets via ternary complexes with oligonucleotides and synthetic receptors
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Evolution of sequence-defined highly functionalized nucleic acid polymers
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Specific Light-Up System for Protein and Metabolite Targets Triggered by Initiation Complex Formation
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Selection, Characterization and Application of Artificial DNA Aptamer Containing Appended Bases with Sub-nanomolar Affinity for a Salivary Biomarker
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Trends in aptamer selection methods and applications
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Synthesis of DNA fragments containing 2′-deoxy-4′-selenonucleoside units using DNA polymerases: comparison of dNTPs with O, S and Se at the 4′-position in replication
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Target-driven DNA association to initiate cyclic assembly of hairpins for biosensing and logic gate operation
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Enzymatic synthesis and reverse transcription of RNAs incorporating 2′-O-carbamoyl uridine triphosphate
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Epigenetic modification of nucleic acids: from basic studies to medical applications
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Optimization of fluorescent 8-heteroaryl-guanine probes for monitoring protein-mediated duplex → G-quadruplex exchange
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Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria
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Conjugating a groove-binding motif to an Ir( iii ) complex for the enhancement of G-quadruplex probe behavior
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Manipulation of a DNA aptamer–protein binding site through arylation of internal guanine residues
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Development of oligonucleotide-based antagonists of Ebola virus protein 24 inhibiting its interaction with karyopherin alpha 1
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In situ condensation of an anti-cancer drug into fibrin gel enabling effective inhibition of tumor cell growth
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Seconds-resolved pharmacokinetic measurements of the chemotherapeutic irinotecan in situ in the living body
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Recent progress in non-native nucleic acid modifications
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Detection and beyond: challenges and advances in aptamer-based biosensors
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Systemic delivery of aptamer–drug conjugates for cancer therapy using enzymatically generated self-assembled DNA nanoparticles
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Recent progress in fluorescent aptasensors for the detection of aflatoxin B1 in food
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Traceless enzymatic synthesis of monodispersed hypermodified oligodeoxyribonucleotide polymers from RNA templates
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Aptamer-based assembly systems for SARS-CoV-2 detection and therapeutics
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Combinatorial and rational synthesis of complex, base-modified aptamer libraries on microarrays
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Non-Equilibrium Capillary Electrophoresis of Equilibrium Mixtures-Based Affinity Separation and Selective Enrichment of a Long-Length DNA Aptamer
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Label-Free and Simple G-quadruplex-based Turn-Off Fluorescence Assay for the Detection of Kanamycin
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Practical Synthesis of Cytidine-5-Carboxamide-Modified Nucleotide Reagents
inferred← citeshttps://doi.org/10.1080/15476286.2016.1236173openalex-snapshot
In vitroevolution of chemically-modified nucleic acid aptamers: Pros and cons, and comprehensive selection strategies
inferred← citeshttps://doi.org/10.1093/nar/gkaa999openalex-snapshot
Enzymatic synthesis of hypermodified DNA polymers for sequence-specific display of four different hydrophobic groups
inferred← citeshttps://doi.org/10.1093/nar/gky1062openalex-snapshot
Tethered imidazole mediated duplex stabilization and its potential for aptamer stabilization
inferred← citeshttps://doi.org/10.1093/nar/gky435openalex-snapshot
N 4-acyl-2′-deoxycytidine-5′-triphosphates for the enzymatic synthesis of modified DNA
inferred← citeshttps://doi.org/10.1134/s0026893318060110openalex-snapshot
Preparation of Modified Combinatorial DNA Libraries via Emulsion PCR with Subsequent Strand Separation
inferred← citeshttps://doi.org/10.1155/2015/808495openalex-snapshot
In VitroSelection of a Single-Stranded DNA Molecular Recognition Element againstClostridium difficileToxin B and Sensitive Detection in Human Fecal Matter
inferred← citeshttps://doi.org/10.1177/09636897221144949openalex-snapshot
Aptamer Technology and Its Applications in Bone Diseases
inferred← citeshttps://doi.org/10.1364/jsapo.2024.16p_b4_13openalex-snapshot
Polyaniline coated U-bent Fiber Optic Aptasensor for Arsenite Detection in Environmental Matrices
inferred← citeshttps://doi.org/10.31083/jmcm27071openalex-snapshot
Aptamer Technology in the Detection of Salivary Biomarkers
inferred← citeshttps://doi.org/10.3389/fchem.2016.00018openalex-snapshot
Modified Nucleoside Triphosphates for In-vitro Selection Techniques
inferred← citeshttps://doi.org/10.3390/app10238755openalex-snapshot
Bifunctional Aptamer Drug Carrier Enabling Selective and Efficient Incorporation of an Approved Anticancer Drug Irinotecan to Fibrin Gels
inferred← citeshttps://doi.org/10.3390/books978-3-0365-1513-7openalex-snapshot
Nucleic Acids Conjugates for Biotechnological Applications
inferred← citeshttps://doi.org/10.3390/ijms16022794openalex-snapshot
In Vitro Selection of Single-Stranded DNA Molecular Recognition Elements against S. aureus Alpha Toxin and Sensitive Detection in Human Serum
inferred← citeshttps://doi.org/10.3390/ijms18112430openalex-snapshot
Nucleic Acid Aptamers: Emerging Applications in Medical Imaging, Nanotechnology, Neurosciences, and Drug Delivery
inferred← citeshttps://doi.org/10.3390/ijms21082683openalex-snapshot
Modified DNA Aptamers for C-Reactive Protein and Lactate Dehydrogenase-5 with Sub-Nanomolar Affinities
inferred← citeshttps://doi.org/10.3390/molecules200916643openalex-snapshot
Generation of Aptamers with an Expanded Chemical Repertoire
inferred← citeshttps://doi.org/10.3390/molecules24193598openalex-snapshot
Inside the Black Box: What Makes SELEX Better?
inferred← citeshttps://doi.org/10.3390/molecules25010003openalex-snapshot
Aptamers Chemistry: Chemical Modifications and Conjugation Strategies
inferred← citeshttps://doi.org/10.3390/ph6091082openalex-snapshot
Structural and Affinity Analyses of G-Quadruplex DNA Aptamers for Camptothecin Derivatives
inferred← citeshttps://doi.org/10.3390/pharmaceutics13060888openalex-snapshot
Hybrid-Type SELEX for the Selection of Artificial Nucleic Acid Aptamers Exhibiting Cell Internalization Activity
inferred← citeshttps://doi.org/10.3390/s131013624openalex-snapshot
Aptamers as Theranostic Agents: Modifications, Serum Stability and Functionalisation
inferred← citeshttps://doi.org/10.33915/etd.5818openalex-snapshot
Identification and Biosensing Application of Molecular Recognition Elements
inferred← citeshttps://doi.org/10.70675/bae8e187z5340z4a18z9cf0z3dec38b94a7copenalex-snapshot
Engineering autonomous and programmable biosensors through synthetic biology : integrating multiplexed biomarker detection and biomolecular signal processing into next-generation diagnostics
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