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Glycoalkaloids and Metabolites Inhibit the Growth of Human Colon (HT29) and Liver (HepG2) Cancer Cells

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1099-1573(199803)12:2<79::aid-ptr192>3.0.co;2-nopenalex-snapshot

Plant-derived glycoalkaloids protect mice against lethal infection withSalmonella typhimurium

inferredcites →https://doi.org/10.1002/jsfa.1292openalex-snapshot

Tomatine, chlorophyll, β‐carotene and lycopene content in tomatoes during growth and maturation

inferredcites →https://doi.org/10.1007/s00268-003-6804-3openalex-snapshot

Doxorubicin Activity Is Enhanced by Hyperthermia in a Model of Ex Vivo Vascular Perfusion of Human Colon Carcinoma

inferredcites →https://doi.org/10.1016/0166-3542(85)90003-8openalex-snapshot

The inactivation of herpes simplex virus by some Solanaceae glycoalkaloids

inferredcites →https://doi.org/10.1016/0304-3835(90)90121-dopenalex-snapshot

Solasodine glycosides. In vitro preferential cytotoxicity for human cancer cells

inferredcites →https://doi.org/10.1016/b978-0-7506-9210-6.50007-4openalex-snapshot

Assessment of Food Safety

inferredcites →https://doi.org/10.1016/s0006-2952(00)00506-2openalex-snapshot

Anticancer activity evaluation of the Solanum glycoalkaloid solamargine

inferredcites →https://doi.org/10.1016/s0031-9422(00)84406-4openalex-snapshot

Commersonine, a new glycoalkaloid from two Solanum species

inferredcites →https://doi.org/10.1016/s0031-9422(00)89518-7openalex-snapshot

Interactions between the glycoalkaloids solasonine and solamargine in relation to inhibition of fungal growth

inferredcites →https://doi.org/10.1016/s0278-6915(00)00050-8openalex-snapshot

Lowering of plasma LDL cholesterol in hamsters by the tomato glycoalkaloid tomatine

inferredcites →https://doi.org/10.1016/s0278-6915(02)00205-3openalex-snapshot

Effect of feeding solanidine, solasodine and tomatidine to non-pregnant and pregnant mice

inferredcites →https://doi.org/10.1016/s0278-6915(97)00038-0openalex-snapshot

Effect of α-tomatine and tomatidine on membrane potential of frog embryos and active transport of ions in frog skin

inferredcites →https://doi.org/10.1016/s0278-6915(97)00164-6openalex-snapshot

Developmental Toxicology of Solamargine and Solasonine Glycoalkaloids in Frog Embryos

inferredcites →https://doi.org/10.1017/s0953756296002973openalex-snapshot

Potato glycoalkaloid impairment of fungal development

inferredcites →https://doi.org/10.1021/jf00043a022openalex-snapshot

Role of Carbohydrate Side Chains of Potato Glycoalkaloids in Developmental Toxicity

inferredcites →https://doi.org/10.1021/jf00051a015openalex-snapshot

Effect of Potato Glycoalkaloids .alpha.-Chaconine and .alpha.-Solanine on Sodium Active Transport in Frog Skin

inferredcites →https://doi.org/10.1021/jf00054a016openalex-snapshot

Acid-Catalyzed Partial Hydrolysis of Carbohydrate Groups of the Potato Glycoalkaloid .alpha.-Chaconine in Alcoholic Solutions

inferredcites →https://doi.org/10.1021/jf00054a017openalex-snapshot

.alpha.-Tomatine Content in Tomato and Tomato Products Determined by HPLC with Pulsed Amperometric Detection

inferredcites →https://doi.org/10.1021/jf020560copenalex-snapshot

Tomato Glycoalkaloids: Role in the Plant and in the Diet

inferredcites →https://doi.org/10.1021/jf021146fopenalex-snapshot

Glycoalkaloid and Calystegine Contents of Eight Potato Cultivars

inferredcites →https://doi.org/10.1021/jf0306845openalex-snapshot

Dehydrotomatine and α-Tomatine Content in Tomato Fruits and Vegetative Plant Tissues

inferredcites →https://doi.org/10.1021/jf60212a002openalex-snapshot

Analysis of mixtures of solanidine and demissidine glycoalkaloids containing identical carbohydrate units

inferredcites →https://doi.org/10.1021/jf60212a047openalex-snapshot

Polyamines in green and roasted coffee

inferredcites →https://doi.org/10.1021/jf9702205openalex-snapshot

Folic Acid Protects against Potato Glycoalkaloid α-Chaconine-Induced Disruption of Frog Embryo Cell Membranes and Developmental Toxicity

inferredcites →https://doi.org/10.1021/jf9804589openalex-snapshot

Dehydrotomatine Content in Tomatoes

inferredcites →https://doi.org/10.1021/jf990252nopenalex-snapshot

Inheritance of Morphological Characters and Glycoalkaloids in Potatoes of Somatic Hybrids between Dihaploid Solanum acaule and Tetraploid Solanum tuberosum

inferredcites →https://doi.org/10.1073/pnas.0732813100openalex-snapshot

Identification of a small molecule inhibitor of the hedgehog signaling pathway: Effects on basal cell carcinoma-like lesions

inferredcites →https://doi.org/10.1080/07352689709701946openalex-snapshot

Potato Glycoalkaloids: Chemistry, Analysis, Safety, and Plant Physiology

inferredcites →https://doi.org/10.1093/jn/126.4.989openalex-snapshot

Feeding of Potato, Tomato and Eggplant Alkaloids Affects Food Consumption and Body and Liver Weights in Mice

inferredcites →https://doi.org/10.1111/j.1365-2621.2000.tb13608.xopenalex-snapshot

Feeding Tomatoes to Hamsters Reduces their Plasma Low‐density Lipoprotein Cholesterol and Triglycerides

inferredcites →https://doi.org/10.1126/science.150.3705.1827openalex-snapshot

Beta-Solamarine: Tumor Inhibitor Isolated from Solanum dulcamara

inferredcites →https://doi.org/10.1126/science.150.3705.1829openalex-snapshot

Differential Enzymatic Activity in Ecological Races of Typha latifolia L.

inferredcites →https://doi.org/10.1358/dof.2002.027.04.667617openalex-snapshot

Tomatine as an adjuvant in malaria vaccine development

inferredcites →https://doi.org/10.1590/s0103-50532002000600017openalex-snapshot

Cytotoxic activities against Ehrlich carcinoma and human K562 leukaemia of alkaloids and flavonoid from two Solanum Species

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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First Synthesis of 12‐Oxosoladulcidine and Its Derivatives as Potential Antitumor Steroidal Alkaloids

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Therapeutic value of steroidal alkaloids in cancer: Current trends and future perspectives

inferred← citeshttps://doi.org/10.1002/jsfa.3302openalex-snapshot

Potato glycoalkaloids: formation and strategies for mitigation

inferred← citeshttps://doi.org/10.1002/jsfa.5951openalex-snapshot

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inferred← citeshttps://doi.org/10.1002/jsfa.7848openalex-snapshot

Health‐beneficial properties of potato and compounds of interest

inferred← citeshttps://doi.org/10.1002/jssc.200900365openalex-snapshot

A multiresidual method for the simultaneous determination of the main glycoalkaloids and flavonoids in fresh and processed tomato (Solanum lycopersicum L.) by LC‐DAD‐MS/MS

inferred← citeshttps://doi.org/10.1002/jssc.201300188openalex-snapshot

Solanidine isolation from Solanum tuberosum by centrifugal partition chromatography

inferred← citeshttps://doi.org/10.1002/jssc.202200804openalex-snapshot

Analysis of steroidal glycoalkaloids and their metabolites in Solanum nigrum fruits based on liquid chromatography‐tandem mass spectrometry and molecular networking

inferred← citeshttps://doi.org/10.1002/med.21346openalex-snapshot

Therapeutic Potential of Steroidal Alkaloids in Cancer and Other Diseases

inferred← citeshttps://doi.org/10.1002/mnfr.200700176openalex-snapshot

Protective effect of dietary tomatine against dibenzo[a,l]pyrene (DBP)‐induced liver and stomach tumors in rainbow trout

inferred← citeshttps://doi.org/10.1002/mnfr.201700241openalex-snapshot

Plasma Metabolomics Reveals Steroidal Alkaloids as Novel Biomarkers of Tomato Intake in Mice

inferred← citeshttps://doi.org/10.1002/ptr.5809openalex-snapshot

Anticancer Properties of Solamargine: A Systematic Review

inferred← citeshttps://doi.org/10.1002/rcm.7727openalex-snapshot

Fragmentation study of major spirosolane‐type glycoalkaloids by collision‐induced dissociation linear ion trap and infrared multiphoton dissociation Fourier transform ion cyclotron resonance mass spectrometry

inferred← citeshttps://doi.org/10.1002/tpg2.20192openalex-snapshot

Steroidal alkaloid biosynthesis is coordinately regulated and differs among tomatoes in the red‐fruited clade

inferred← citeshttps://doi.org/10.1007/0-387-24980-x_12openalex-snapshot

Biological Effects of Maillard Browning Products That May Affect Acrylamide Safety in Food

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Saponin Synthesis and Function

inferred← citeshttps://doi.org/10.1007/978-2-8178-0375-3_32openalex-snapshot

Solanum

inferred← citeshttps://doi.org/10.1007/978-3-030-28683-5_2openalex-snapshot

The Potato and Its Contribution to the Human Diet and Health

inferred← citeshttps://doi.org/10.1007/978-3-319-26065-5_2openalex-snapshot

Solanum tuberosum

inferred← citeshttps://doi.org/10.1007/978-3-319-54528-8_37-1openalex-snapshot

Roots and Tubers as Functional Foods

inferred← citeshttps://doi.org/10.1007/978-3-319-78030-6_37openalex-snapshot

Roots and Tubers as Functional Foods

inferred← citeshttps://doi.org/10.1007/978-3-540-74541-9_7openalex-snapshot

Terpenoids (Isoprenoids)

inferred← citeshttps://doi.org/10.1007/978-94-007-5628-1_41openalex-snapshot

Solanum lycopersicum

inferred← citeshttps://doi.org/10.1007/978-94-007-5628-1_43openalex-snapshot

Solanum melongena

inferred← citeshttps://doi.org/10.1007/978-981-15-7662-1_12openalex-snapshot

New Health-Promoting Compounds in Potatoes

inferred← citeshttps://doi.org/10.1007/s00217-013-1977-yopenalex-snapshot

Effects of liver S9 enzymes on somalargine and solasodine cytotoxicity and mass spectrometric fragmentation

inferred← citeshttps://doi.org/10.1007/s00253-009-2315-yopenalex-snapshot

Microbial conversion of ruscogenin by Gliocladium deliquescens NRRL1086: glycosylation at C-1

inferred← citeshttps://doi.org/10.1007/s10238-012-0198-1openalex-snapshot

Aberrant activation of Hedgehog pathway in Nasopharyngeal carcinoma

inferred← citeshttps://doi.org/10.1007/s11418-013-0757-0openalex-snapshot

Antiproliferative activity of Solanum lycocarpum alkaloidic extract and their constituents, solamargine and solasonine, in tumor cell lines

inferred← citeshttps://doi.org/10.1007/s11418-024-01830-1openalex-snapshot

Search for new steroidal glycosides with anti-cancer potential from natural resources

inferred← citeshttps://doi.org/10.1007/s11540-015-9314-4openalex-snapshot

Next Generation Sequencing Bulk Segregant Analysis of Potato Support that Differential Flux into the Cholesterol and Stigmasterol Metabolite Pools Is Important for Steroidal Glycoalkaloid Content

inferred← citeshttps://doi.org/10.1007/s11540-022-09560-1openalex-snapshot

Evaluation of Genotoxic and Apoptotic Effects of Sprouted Potato

inferred← citeshttps://doi.org/10.1007/s11540-025-09920-7openalex-snapshot

Glycoalkaloids in Potato: A Comprehensive Overview of Accumulation, Detection and Mitigation Strategies

inferred← citeshttps://doi.org/10.1007/s11745-005-1473-2openalex-snapshot

Astonishing diversity of natural surfactants: 6. Biologically active marine and terrestrial alkaloid glycosides

inferred← citeshttps://doi.org/10.1007/s11816-019-00549-wopenalex-snapshot

Medicinal metabolites with common biosynthetic pathways in Solanum nigrum

inferred← citeshttps://doi.org/10.1007/s12013-011-9152-1openalex-snapshot

α-Tomatine Suppresses Invasion and Migration of Human Non-Small Cell Lung Cancer NCI-H460 Cells Through Inactivating FAK/PI3K/Akt Signaling Pathway and Reducing Binding Activity of NF-κB

inferred← citeshttps://doi.org/10.1007/s12013-012-9465-8openalex-snapshot

Suppression of 12-O-Tetradecanoylphorbol-13-Acetate-Induced MCF-7 Breast Adenocarcinoma Cells Invasion/Migration by α-Tomatine Through Activating PKCα/ERK/NF-κB-Dependent MMP-2/MMP-9 Expressions

inferred← citeshttps://doi.org/10.1007/s12013-024-01406-6openalex-snapshot

Tomatidine, a Steroidal Alkaloid, Synergizes with Cisplatin to Inhibit Cell Viability and Induce Cell Death Selectively on FLT3-ITD+ Acute Myeloid Leukemia Cells

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Solanum nigrum Linn.: Advances in anti-cancer activity and mechanism in digestive system tumors

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Antioxidant Properties of Cultivars and Selections from the Colorado Potato Breeding Program

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inferred← citeshttps://doi.org/10.1007/s13277-015-4528-2openalex-snapshot

Anticancer function of α-solanine in lung adenocarcinoma cells by inducing microRNA-138 expression

inferred← citeshttps://doi.org/10.1007/s13659-016-0103-9openalex-snapshot

Spiralosides A–C, Three New C27-Steroidal Glycoalkaloids from the Fruits of Solanum spirale

inferred← citeshttps://doi.org/10.1007/s42535-022-00502-3openalex-snapshot

Micropropagation of an ethnomedicinal plant Solanum torvum Swartz

inferred← citeshttps://doi.org/10.1007/s42535-023-00722-1openalex-snapshot

Effect of plant growth regulators on callus induction in Solanum torvum SW: a medicinal plant

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inferred← citeshttps://doi.org/10.1016/b978-0-12-374349-7.00014-3openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/b978-0-12-380886-8.10023-6openalex-snapshot

Use of Potato Flour in Bread and Flat Bread

inferred← citeshttps://doi.org/10.1016/b978-0-12-800002-1.00006-6openalex-snapshot

Vitamins, Phytonutrients, and Minerals in Potato

inferred← citeshttps://doi.org/10.1016/b978-0-12-800002-1.00007-8openalex-snapshot

Glycoalkaloids and Calystegine Alkaloids in Potatoes

inferred← citeshttps://doi.org/10.1016/b978-0-12-811521-3.00001-6openalex-snapshot

Methods for Extractions of Value-Added Nutraceuticals From Lignocellulosic Wastes and Their Health Application

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Traditional Foods From Tropical Root and Tuber Crops

inferred← citeshttps://doi.org/10.1016/j.bbamem.2008.06.004openalex-snapshot

Comparison of the interaction of tomatine with mixed monolayers containing phospholipid, egg sphingomyelin, and sterols

inferred← citeshttps://doi.org/10.1016/j.bcp.2010.04.016openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.biori.2019.06.004openalex-snapshot

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Steroidal alkaloids isolated from Veratrum grandiflorum Loes. as novel Smoothened inhibitors with anti-proliferation effects on DAOY medulloblastoma cells

inferred← citeshttps://doi.org/10.1016/j.carbpol.2012.05.073openalex-snapshot

Enhancement of amygdalin activated with β-d-glucosidase on HepG2 cells proliferation and apoptosis

inferred← citeshttps://doi.org/10.1016/j.cbi.2005.08.003openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.cbi.2013.03.016openalex-snapshot

Tomatidine inhibits invasion of human lung adenocarcinoma cell A549 by reducing matrix metalloproteinases expression

inferred← citeshttps://doi.org/10.1016/j.cbi.2017.03.005openalex-snapshot

Solasodine inhibits invasion of human lung cancer cell through downregulation of miR-21 and MMPs expression

inferred← citeshttps://doi.org/10.1016/j.cclet.2010.04.020openalex-snapshot

Synthesis and evaluation of in vitro anticancer activity of novel solasodine derivatives

inferred← citeshttps://doi.org/10.1016/j.chroma.2004.04.049openalex-snapshot

Analysis of biologically active compounds in potatoes (Solanum tuberosum), tomatoes (Lycopersicon esculentum), and jimson weed (Datura stramonium) seeds

inferred← citeshttps://doi.org/10.1016/j.colcom.2018.11.001openalex-snapshot

IN VITRO Anticancer Activity and Physicochemical Properties of SOLANUM LYCOCARPUM Alkaloidic Extract Loaded in Natural Lipid-Based Nanoparticles

inferred← citeshttps://doi.org/10.1016/j.ejmech.2013.11.019openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.ejpb.2014.01.010openalex-snapshot

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inferred← citeshttps://doi.org/10.1016/j.fct.2005.11.007openalex-snapshot

α-Chaconine, a potato glycoalkaloid, induces apoptosis of HT-29 human colon cancer cells through caspase-3 activation and inhibition of ERK 1/2 phosphorylation

inferred← citeshttps://doi.org/10.1016/j.fct.2009.05.011openalex-snapshot

α-Tomatine inactivates PI3K/Akt and ERK signaling pathways in human lung adenocarcinoma A549 cells: Effect on metastasis

inferred← citeshttps://doi.org/10.1016/j.fct.2012.07.028openalex-snapshot

Evaluation of cytotoxic, genotoxic and antigenotoxic potential of Solanum lycocarpum fruits glicoalkaloid extract in V79 cells

inferred← citeshttps://doi.org/10.1016/j.fct.2018.07.011openalex-snapshot

Diosgenin induces genotoxic and mutagenic effects on HepG2 cells

inferred← citeshttps://doi.org/10.1016/j.febslet.2008.05.049openalex-snapshot

Tomatidine inhibits iNOS and COX‐2 through suppression of NF‐κB and JNK pathways in LPS‐stimulated mouse macrophages

inferred← citeshttps://doi.org/10.1016/j.fitote.2010.03.001openalex-snapshot

Regeneration, in vitro glycoalkaloids production and evaluation of bioactivity of callus methanolic extract of Solanum tuberosum L.

inferred← citeshttps://doi.org/10.1016/j.foodchem.2021.130461openalex-snapshot

Biosynthesis of α-solanine and α-chaconine in potato leaves (Solanum tuberosum L.) – A 13CO2 study

inferred← citeshttps://doi.org/10.1016/j.foodchem.2022.133261openalex-snapshot

Alpha-tomatine and the two sides of the same coin: An anti-nutritional glycoalkaloid with potential in human health

inferred← citeshttps://doi.org/10.1016/j.foodchem.2023.136368openalex-snapshot

Health-Promoting compounds in Potatoes: Tuber exhibiting great potential for human health

inferred← citeshttps://doi.org/10.1016/j.foodchem.2024.141346openalex-snapshot

Discovery of steroidal alkaloid metabolites and their accumulation in pigs after short-term tomato consumption

inferred← citeshttps://doi.org/10.1016/j.foodchem.2025.147259openalex-snapshot

Analytical strategies by liquid chromatography for the determination of glycoalkaloids in potatoes, tomatoes, eggplants and related products: Current knowledge, applications, and future perspectives

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Comprehensive profiling and risk assessment of glycoalkaloids and their aglycones in commercial potato-based snacks using miniaturized extraction and purification coupled with UHPLC-MS/MS

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Potato protein as an emerging high-quality: Source, extraction, purification, properties (functional, nutritional, physicochemical, and processing), applications, and challenges using potato protein

inferred← citeshttps://doi.org/10.1016/j.gene.2017.06.054openalex-snapshot

The effect of tomatine on metastasis related matrix metalloproteinase (MMP) activities in breast cancer cell model

inferred← citeshttps://doi.org/10.1016/j.hermed.2022.100557openalex-snapshot

A review of potential anti-cancer properties of some selected medicinal plants grown in Iran

inferred← citeshttps://doi.org/10.1016/j.hpj.2023.05.019openalex-snapshot

Finding the balance: Modifying the cholesterol and steroidal glycoalkaloid synthesis pathway in tomato (Solanum lycopersicum L.) for human health, fruit flavor, and plant defense

inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.124411openalex-snapshot

Evaluation of in vivo and in vitro efficacy of solasonine/solamargine-loaded lipid-polymer hybrid nanoparticles against bladder cancer

inferred← citeshttps://doi.org/10.1016/j.intimp.2025.114841openalex-snapshot

Chondrocyte-targeted α-Solanine through HIF-1α regulating glycolysis to reduce the ferroptosis of chondrocyte in osteoarthritis

inferred← citeshttps://doi.org/10.1016/j.jchromb.2015.01.017openalex-snapshot

An UPLC-MS/MS method for determination of solasonine in rat plasma and its application of a pharmacokinetic and bioavailability study

inferred← citeshttps://doi.org/10.1016/j.jdermsci.2011.04.003openalex-snapshot

Solanum incanum extract (SR-T100) induces human cutaneous squamous cell carcinoma apoptosis through modulating tumor necrosis factor receptor signaling pathway

inferred← citeshttps://doi.org/10.1016/j.jdermsci.2018.02.015openalex-snapshot

Efficacy and safety of topical SR-T100 gel in treating actinic keratosis in Taiwan: A Phase III randomized double-blind vehicle-controlled parallel trial

inferred← citeshttps://doi.org/10.1016/j.jep.2007.09.023openalex-snapshot

Induction of apoptosis in HepG2 cells by solanine and Bcl-2 protein

inferred← citeshttps://doi.org/10.1016/j.jep.2013.04.014openalex-snapshot

Ethnopharmacological and bioactivity guided investigation of five TCM anticancer herbs

inferred← citeshttps://doi.org/10.1016/j.jfca.2016.05.011openalex-snapshot

Analysis of protein amino acids, non-protein amino acids and metabolites, dietary protein, glucose, fructose, sucrose, phenolic, and flavonoid content and antioxidative properties of potato tubers, peels, and cortexes (pulps)

inferred← citeshttps://doi.org/10.1016/j.jff.2016.10.005openalex-snapshot

Antiproliferative effects of α-tomatine are associated with different cell death modalities in human colon cancer cells

inferred← citeshttps://doi.org/10.1016/j.jpba.2011.04.007openalex-snapshot

Quantitative determination and pharmacokinetic study of solamargine in rat plasma by liquid chromatography–mass spectrometry

inferred← citeshttps://doi.org/10.1016/j.jpba.2011.11.006openalex-snapshot

Quantitative determination and pharmacokinetic study of casticin in rat plasma by liquid chromatography–mass spectrometry

inferred← citeshttps://doi.org/10.1016/j.jsbmb.2013.02.018openalex-snapshot

Synthesis of sex hormone-derived modified steroids possessing antiproliferative activity

inferred← citeshttps://doi.org/10.1016/j.jsbmb.2017.03.009openalex-snapshot

Neurotoxicity of the steroidal alkaloids tomatine and tomatidine is RIP1 kinase- and caspase-independent and involves the eIF2α branch of the endoplasmic reticulum

inferred← citeshttps://doi.org/10.1016/j.jscs.2011.10.003openalex-snapshot

Solanopubamine, a rare steroidal alkaloid from Solanum schimperianum: Synthesis of some new alkyl and acyl derivatives, their anticancer and antimicrobial evaluation

inferred← citeshttps://doi.org/10.1016/j.jsps.2016.05.003openalex-snapshot

High-performance thin layer chromatography based assay and stress study of a rare steroidal alkaloid solanopubamine in six species of Solanum grown in Saudi Arabia

inferred← citeshttps://doi.org/10.1016/j.msec.2020.111460openalex-snapshot

Cytotoxic and chemosensitizing effects of glycoalkaloidic extract on 2D and 3D models using RT4 and patient derived xenografts bladder cancer cells

inferred← citeshttps://doi.org/10.1016/j.plaphy.2022.09.034openalex-snapshot

Stress induced production of plant secondary metabolites in vegetables: Functional approach for designing next generation super foods

inferred← citeshttps://doi.org/10.1016/j.plaphy.2026.111311openalex-snapshot

Phytochemical profile, biological activities, and biotic stress factors of Solanum tuberosum

inferred← citeshttps://doi.org/10.1016/j.sajb.2017.06.002openalex-snapshot

The steroidal glycoalkaloids solamargine and solasonine in Solanum plants

inferred← citeshttps://doi.org/10.1016/j.seppur.2018.02.030openalex-snapshot

An efficient approach for the enzyme-enhanced extraction of camptothecin and 10-hydroxycamptothecin from the samara of Camptotheca acuminata using an ionic liquid solution

inferred← citeshttps://doi.org/10.1016/j.steroids.2010.10.006openalex-snapshot

Antiproliferative effects of some novel synthetic solanidine analogs on HL-60 human leukemia cells in vitro

inferred← citeshttps://doi.org/10.1016/j.steroids.2012.05.002openalex-snapshot

Application of hypoiodite-mediated aminyl radical cyclization to synthesis of solasodine acetate

inferred← citeshttps://doi.org/10.1016/j.steroids.2012.10.009openalex-snapshot

Synthesis and investigation of the anticancer effects of estrone-16-oxime ethers in vitro

inferred← citeshttps://doi.org/10.1016/j.steroids.2021.108933openalex-snapshot

The steroidal alkaloids α-tomatine and tomatidine: Panorama of their mode of action and pharmacological properties

inferred← citeshttps://doi.org/10.1016/j.steroids.2026.109793openalex-snapshot

Veratrum-derived steroidal alkaloids: from scaffold to pharmacological leads

inferred← citeshttps://doi.org/10.1016/j.tetlet.2015.01.149openalex-snapshot

Facile synthesis of solasodine based on a mild halogenation-ring opening reaction of spiroketals in steroidal sapogenins

inferred← citeshttps://doi.org/10.1016/j.tetlet.2015.10.043openalex-snapshot

Direct amination of EF spiroketal in steroidal sapogenins: an efficient synthetic strategy and method for related alkaloids

inferred← citeshttps://doi.org/10.1016/s1005-9040(07)60065-8openalex-snapshot

Modification of Sugar Chains in Glycoalkaloids and Variation of Anticancer Activity

inferred← citeshttps://doi.org/10.1016/s1674-6384(16)60026-6openalex-snapshot

Induction of Solasonine on Apoptosis of Human Breast Cancer Bcap-37 Cells through Mitochondria-Mediated Pathway

inferred← citeshttps://doi.org/10.1016/s2095-3119(19)62718-8openalex-snapshot

Inheritance of steroidal glycoalkaloids in potato tuber flesh

inferred← citeshttps://doi.org/10.1021/acs.jafc.0c05906openalex-snapshot

Identification of Novel Iso-Esculeoside B from Tomato Fruits and LC–MS/MS-Based Food Screening for Major Dietary Steroidal Alkaloids Focused on Esculeosides

inferred← citeshttps://doi.org/10.1021/acs.jafc.2c02578openalex-snapshot

Quantitation of Toxic Steroidal Glycoalkaloids and Newly Identified Saponins in Post-Harvest Light-Stressed Potato (Solanum tuberosum L.) Varieties

inferred← citeshttps://doi.org/10.1021/acs.jafc.2c03418openalex-snapshot

Soluble Free, Soluble Conjugated, and Insoluble Bound Phenolics in Tomato Seeds and Their Radical Scavenging and Antiproliferative Activities

inferred← citeshttps://doi.org/10.1021/acs.jafc.4c03071openalex-snapshot

Potato Berries as a Valuable Source of Compounds Potentially Applicable in Crop Protection and Pharmaceutical Sectors: A Review

inferred← citeshttps://doi.org/10.1021/acs.jafc.5b00818openalex-snapshot

Chemistry and Anticarcinogenic Mechanisms of Glycoalkaloids Produced by Eggplants, Potatoes, and Tomatoes

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.8b00573openalex-snapshot

Revision of the Structure of N,O-Diacetylsolasodine. Unusual Epimerization at the Spiro Carbon Atom during Acetylation of Solasodine

inferred← citeshttps://doi.org/10.1021/acs.joc.7b01133openalex-snapshot

Divergent Synthesis of Solanidine and 22-epi-Solanidine

inferred← citeshttps://doi.org/10.1021/acs.orglett.6b01320openalex-snapshot

Synthesis of Demissidine and Solanidine

inferred← citeshttps://doi.org/10.1021/acsptsci.3c00013openalex-snapshot

Khasianine Affects the Expression of Sugar-Sensitive Proteins in Pancreatic Cancer Cells, Which Are Altered in Data from the Rat Model and Patients

inferred← citeshttps://doi.org/10.1021/ja808636eopenalex-snapshot

Efficient Approach to Androstene-Fused Arylpyrazolines as Potent Antiproliferative Agents. Experimental and Theoretical Studies of Substituent Effects on BF3-Catalyzed Intramolecular [3 + 2] Cycloadditions of Olefinic Phenylhydrazones

inferred← citeshttps://doi.org/10.1021/jf072423ropenalex-snapshot

α-Chaconine-reduced Metastasis Involves a PI3K/Akt Signaling Pathway with Downregulation of NF-κB in Human Lung Adenocarcinoma A549 cells

inferred← citeshttps://doi.org/10.1021/jf0730486openalex-snapshot

Review of Methods for the Reduction of Dietary Content and Toxicity of Acrylamide

inferred← citeshttps://doi.org/10.1021/jf100162jopenalex-snapshot

Changes in Free Amino Acid, Phenolic, Chlorophyll, Carotenoid, and Glycoalkaloid Contents in Tomatoes during 11 Stages of Growth and Inhibition of Cervical and Lung Human Cancer Cells by Green Tomato Extracts

inferred← citeshttps://doi.org/10.1021/jf200439qopenalex-snapshot

Bioactivities of Glycoalkaloids and Their Aglycones from Solanum Species

inferred← citeshttps://doi.org/10.1021/jf202791jopenalex-snapshot

Free Amino Acid and Phenolic Contents and Antioxidative and Cancer Cell-Inhibiting Activities of Extracts of 11 Greenhouse-Grown Tomato Varieties and 13 Tomato-Based Foods

inferred← citeshttps://doi.org/10.1021/jf3003027openalex-snapshot

Structure–Activity Relationships of α-, β 1 -, γ-, and δ-Tomatine and Tomatidine against Human Breast (MDA-MB-231), Gastric (KATO-III), and Prostate (PC3) Cancer Cells

inferred← citeshttps://doi.org/10.1021/jf402654eopenalex-snapshot

Anticarcinogenic, Cardioprotective, and Other Health Benefits of Tomato Compounds Lycopene, α-Tomatine, and Tomatidine in Pure Form and in Fresh and Processed Tomatoes

inferred← citeshttps://doi.org/10.1021/jf5040288openalex-snapshot

The Tomato Glycoalkaloid α-Tomatine Induces Caspase-Independent Cell Death in Mouse Colon Cancer CT-26 Cells and Transplanted Tumors in Mice

inferred← citeshttps://doi.org/10.1021/jf8012794openalex-snapshot

Acute Toxicity of High Doses of the Glycoalkaloids, α-Solanine and α-Chaconine, in the Syrian Golden Hamster

inferred← citeshttps://doi.org/10.1021/jf802351copenalex-snapshot

Isolation, Characterization, and Surfactant Properties of the Major Triterpenoid Glycosides from Unripe Tomato Fruits

inferred← citeshttps://doi.org/10.1021/jf802631topenalex-snapshot

Distribution of Glycoalkaloids in Potato Tubers of 59 Accessions of Two Wild and Five Cultivated Solanum Species

inferred← citeshttps://doi.org/10.1021/jf8037902openalex-snapshot

Involvement of Ethylene in the Accumulation of Esculeoside A during Fruit Ripening of Tomato (Solanum lycopersicum)

inferred← citeshttps://doi.org/10.1021/jf900364jopenalex-snapshot

Tomatine-Containing Green Tomato Extracts Inhibit Growth of Human Breast, Colon, Liver, and Stomach Cancer Cells

inferred← citeshttps://doi.org/10.1038/cddis.2015.219openalex-snapshot

α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway

inferred← citeshttps://doi.org/10.1038/s41598-017-05568-7openalex-snapshot

Tomatoes protect against development of UV-induced keratinocyte carcinoma via metabolomic alterations

inferred← citeshttps://doi.org/10.1038/s41598-018-36089-6openalex-snapshot

Bioactive glycoalkaloides isolated from Solanum melongena fruit peels with potential anticancer properties against hepatocellular carcinoma cells

inferred← citeshttps://doi.org/10.1038/s41598-022-09032-zopenalex-snapshot

The comparisons of expression pattern reveal molecular regulation of fruit metabolites in S. nigrum and S. lycopersicum

inferred← citeshttps://doi.org/10.1039/c1fo10030kopenalex-snapshot

Mechanism of Hericium erinaceus (Yamabushitake) mushroom-induced apoptosis of U937 human monocytic leukemia cells

inferred← citeshttps://doi.org/10.1039/c9ob01888copenalex-snapshot

The synthesis of solasodine F-homo-analogues

inferred← citeshttps://doi.org/10.1039/d4cc01850hopenalex-snapshot

Convergent synthesis of glycoalkaloids solasonine and its saponin derivative

inferred← citeshttps://doi.org/10.1055/s-0042-113000openalex-snapshot

Solasodine Induces Apoptosis, Affects Autophagy, and Attenuates Metastasis in Ovarian Cancer Cells

inferred← citeshttps://doi.org/10.1074/jbc.m112.367680openalex-snapshot

Targeting the Sonic Hedgehog Pathway in Keratocystic Odontogenic Tumor

inferred← citeshttps://doi.org/10.1080/01140671.2013.870219openalex-snapshot

Transcriptional expression of seven key genes involved in steroidal glycoalkaloid biosynthesis in potato microtubers

inferred← citeshttps://doi.org/10.1080/01635580903532358openalex-snapshot

The Bioactive Compounds α-Chaconine and Gallic Acid in Potato Extracts Decrease Survival and Induce Apoptosis in LNCaP and PC3 Prostate Cancer Cells

inferred← citeshttps://doi.org/10.1080/07328303.2019.1642345openalex-snapshot

Strategies on the construction of 1,2-branched trans-β-glycosidic linkages and their applications in the synthesis of saponins

inferred← citeshttps://doi.org/10.1080/07352689.2022.2057749openalex-snapshot

Bioactive compounds of potato (Solanum tuberosum L.) juice: from industry waste to food and medical applications

inferred← citeshttps://doi.org/10.1080/10286020.2010.497997openalex-snapshot

Antinociceptive activity of steroid alkaloids isolated from Solanum trilobatum Linn.

inferred← citeshttps://doi.org/10.1080/10408390903041996openalex-snapshot

Potatoes and Human Health

inferred← citeshttps://doi.org/10.1080/10408398.2016.1139542openalex-snapshot

Impact of potato processing on nutrients, phytochemicals, and human health

inferred← citeshttps://doi.org/10.1080/10408398.2023.2212766openalex-snapshot

Physiological functions, pharmacological aspects and nutritional importance of green tomato- a future food

inferred← citeshttps://doi.org/10.1080/10428190802510315openalex-snapshot

The hedgehog inhibitor cyclopamine induces apoptosis in leukemic cellsin vitro

inferred← citeshttps://doi.org/10.1080/13880200701538690openalex-snapshot

Anticancer Activity of Steroid Alkaloids Isolated from Solanum aculeastrum .

inferred← citeshttps://doi.org/10.1080/13880209.2016.1175022openalex-snapshot

In vitrocytotoxicity, genotoxicity and antigenotoxicity assessment ofSolanum lycocarpumhydroalcoholic extract

inferred← citeshttps://doi.org/10.1080/14786410903370783openalex-snapshot

Anti-inflammatory activity of an alkaloid fromSolanum trilobatumon acute and chronic inflammation models

inferred← citeshttps://doi.org/10.1080/14786419.2026.2711122openalex-snapshot

Plant-derived natural products against hepatocellular carcinoma: chemical diversity, mechanisms of action, and organ-based classification

inferred← citeshttps://doi.org/10.1080/23311932.2016.1138595openalex-snapshot

Hydroxycinnamic acid functional ingredients and their biosynthetic genes in tubers of Solanum tuberosum Group Phureja

inferred← citeshttps://doi.org/10.1089/ars.2022.0179openalex-snapshot

Novel Insights on Ferroptosis Modulation as Potential Strategy for Cancer Treatment: When Nature Kills

inferred← citeshttps://doi.org/10.1089/jmf.2009.0103openalex-snapshot

Effect of Ditaxin and Heteranthin and Inhibitory Effect of Ditaxis heterantha Extract on L5178Y Tumor Development in Mice

inferred← citeshttps://doi.org/10.1097/01.cji.0000187958.38179.a9openalex-snapshot

Antitumor Efficacy of the Novel Chemotherapeutic Agent Coramsine Is Potentiated by Cotreatment With CpG-Containing Oligodeoxynucleotides

inferred← citeshttps://doi.org/10.1109/icbbe.2009.5162948openalex-snapshot

Induction of Apoptosis in HepG2 Cells by Solanine

inferred← citeshttps://doi.org/10.1111/1750-3841.12443openalex-snapshot

Effect of Genotype and Environment on the Glycoalkaloid Content of Rare, Heritage, and Commercial Potato Varieties

inferred← citeshttps://doi.org/10.1111/ijfs.14330openalex-snapshot

Potato Glycoalkaloids: occurrence, biological activities and extraction for biovalorisation – a review

inferred← citeshttps://doi.org/10.1111/j.1872-034x.2007.00006.xopenalex-snapshot

Effect of Solanum trilobatum on hepatic drug metabolising enzymes during diethylnitrosamine‐induced hepatocarcinogenesis promoted by Phenobarbital in rat

inferred← citeshttps://doi.org/10.1111/jcmm.17343openalex-snapshot

Solasonine induces apoptosis of the SGC‐7901 human gastric cancer cell line in vitro via the mitochondria‐mediated pathway

inferred← citeshttps://doi.org/10.11144/javeriana.10554.42354openalex-snapshot

Análisis del efecto de la α-Solanina en las características citomorfológicas de células vivas adheridas y su relación con la expresión del gen Shroom3

inferred← citeshttps://doi.org/10.1155/2016/3631647openalex-snapshot

Roots and Tuber Crops as Functional Foods: A Review on Phytochemical Constituents and Their Potential Health Benefits

inferred← citeshttps://doi.org/10.1159/000447807openalex-snapshot

α-Solanine Modulates the Radiosensitivity of Esophageal Cancer Cells by Inducing MicroRNA 138 Expression

inferred← citeshttps://doi.org/10.11606/d.60.2010.tde-16112010-202039openalex-snapshot

Obtenção de extrato padronizado de Solanum lycicarpum A. St.-Hil. contendo glicoalcalóides, desenvolvimento de método analítico por CLAE e de forma farmacêutica de uso tópico

inferred← citeshttps://doi.org/10.11606/d.60.2012.tde-05072012-104926openalex-snapshot

Heterosídeos alcaloídicos de Solanum lycocarpum A. St.-Hil.: avaliação das atividades contra fungos dermatófitos e câncer de pele

inferred← citeshttps://doi.org/10.11606/d.60.2017.tde-03052017-155607openalex-snapshot

Desenvolvimento de nanopartículas lipídicas sólidas no carreamento de extrato alcaloídico de Solanum lycocarpum e avaliação biológica in vitro em células de câncer de bexiga

inferred← citeshttps://doi.org/10.11606/t.60.2022.tde-18082022-161940openalex-snapshot

Desenvolvimento, caracterização e atividade antitumoral de nanocarreador híbrido com extrato alcaloídico de Solanum lycocarpum

inferred← citeshttps://doi.org/10.1177/1091581811423845openalex-snapshot

Sanguinarine Induces Apoptosis of HT-29 Human Colon Cancer Cells via the Regulation of Bax/Bcl-2 Ratio and Caspase-9-Dependent Pathway

inferred← citeshttps://doi.org/10.1177/1934578x0800300420openalex-snapshot

Toxic Chemical Compounds of the Solanaceae

inferred← citeshttps://doi.org/10.1248/bpb.33.1685openalex-snapshot

.ALPHA.-Solanine Inhibits Human Melanoma Cell Migration and Invasion by Reducing Matrix Metalloproteinase-2/9 Activities

inferred← citeshttps://doi.org/10.1248/bpb.33.622openalex-snapshot

.ALPHA.-Chaconine Inhibits Angiogenesis in Vitro by Reducing Matrix Metalloproteinase-2

inferred← citeshttps://doi.org/10.12677/hjfns.2016.52004openalex-snapshot

Progress of Anti-Cancer Function of Solanine

inferred← citeshttps://doi.org/10.12692/ijb/27.6.14-24openalex-snapshot

Alpha-tomatine induces ROS-mediated mitochondrial apoptosis in laryngeal carcinoma (HEp-2) cells

inferred← citeshttps://doi.org/10.13050/foodengprog.2014.18.3.222openalex-snapshot

Physicochemical Properties of a Betatini Variety of Lycopersicon esculentum var. cerasiforme (Cherry Tomato)

inferred← citeshttps://doi.org/10.13140/rg.2.2.35878.52800openalex-snapshot

Effect of wounding and Light exposure on sterol, glycoalkaloid and calystegine levels in potato plants (Solanum tuberosum L. group Tuberosum)

inferred← citeshttps://doi.org/10.1371/journal.pone.0018915openalex-snapshot

Alpha-Tomatine Induces Apoptosis and Inhibits Nuclear Factor-Kappa B Activation on Human Prostatic Adenocarcinoma PC-3 Cells

inferred← citeshttps://doi.org/10.1371/journal.pone.0044093openalex-snapshot

α-Tomatine-Mediated Anti-Cancer Activity In Vitro and In Vivo through Cell Cycle- and Caspase-Independent Pathways

inferred← citeshttps://doi.org/10.1371/journal.pone.0087868openalex-snapshot

Antitumor Efficacy of α-Solanine against Pancreatic Cancer In Vitro and In Vivo

inferred← citeshttps://doi.org/10.1371/journal.pone.0118104openalex-snapshot

A Click Approach to Novel D-Ring-Substituted 16α-Triazolylestrone Derivatives and Characterization of Their Antiproliferative Properties

inferred← citeshttps://doi.org/10.14232/phd.1849openalex-snapshot

Anticancer effects of estrone derivatives and nonsteroidal 17β-hydroxysteroid dehydrogenase type 1 inhibitors

inferred← citeshttps://doi.org/10.14232/phd.2679openalex-snapshot

Characterization of antiproliferative activities of triazolyl-steroid derivatives

inferred← citeshttps://doi.org/10.14511/jasa.2013.020401openalex-snapshot

Cytotoxic and apoptotic potential of potato glycoalkaloids in a number of cancer cell lines

inferred← citeshttps://doi.org/10.14670/hh-18-717openalex-snapshot

In vitro and in vivo antineoplastic activities of solamargine in colorectal cancer through the suppression of PI3K/AKT pathway.

inferred← citeshttps://doi.org/10.1556/jpc.22.2009.1.8openalex-snapshot

Changes in glycoalkaloid composition during potato processing: Simple and reliable quality control by HPTLC

inferred← citeshttps://doi.org/10.1590/1678-4324-2020190395openalex-snapshot

The α-Tomatine Exhibits Antiproliferative Activity, Rupture of Cell Membranes and Induces the Expression of APC Gene in the Human Colorectal Adenocarcinoma Cell Line (Ht-29)

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