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Metabolic Pathways of T-2 Toxin in in Vivo and in Vitro Systems of Wistar Rats

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bms.1200121203openalex-snapshot
Identification of ISO-TC-1 as a new T-2 toxin metabolite in cow urine
inferredcites →https://doi.org/10.1006/taap.1997.8338openalex-snapshot
T-2 Toxin Induces Thymic Apoptosisin Vivoin Mice
inferredcites →https://doi.org/10.1007/s10565-006-0180-3openalex-snapshot
Improvement of human dendritic cell culture for immunotoxicological investigations
inferredcites →https://doi.org/10.1007/s11046-005-0199-7openalex-snapshot
Natural Occurrence of 16 Fusarium Toxins in Grains and Feedstuffs of Plant Origin from Germany
inferredcites →https://doi.org/10.1007/s12550-012-0134-yopenalex-snapshot
Intestinal metabolism of T-2 toxin in the pig cecum model
inferredcites →https://doi.org/10.1016/0015-6264(81)90300-xopenalex-snapshot
Metabolic fate of T-2 toxin in a lactating cow
inferredcites →https://doi.org/10.1016/0041-008x(90)90151-jopenalex-snapshot
In vivo effects of T-2 mycotoxin on synthesis of proteins and DNA in rat tissues
inferredcites →https://doi.org/10.1016/0278-6915(96)00118-4openalex-snapshot
Differential effects of T-2 toxin on bone marrow and spleen erythropoiesis in mice
inferredcites →https://doi.org/10.1016/0378-4347(87)80058-0openalex-snapshot
Metabolism of three trichothecene ycotoxins, T-2 toxin, diacetoxyscirpenol and deoxynivalenol, by bovne rumen microorganisms
inferredcites →https://doi.org/10.1016/j.drudis.2008.11.002openalex-snapshot
Liquid chromatography–mass spectrometry in in vitro drug metabolite screening
inferredcites →https://doi.org/10.1016/j.ijfoodmicro.2007.02.009openalex-snapshot
Occurrence of Fusarium species and trichothecenes in Nigerian maize
inferredcites →https://doi.org/10.1016/j.jpba.2012.04.004openalex-snapshot
In vitro metabolism of cyadox in rat, chicken and swine using ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry
inferredcites →https://doi.org/10.1016/j.tox.2005.01.007openalex-snapshot
T-2 toxin immunotoxicity on human B and T lymphoid cell lines
inferredcites →https://doi.org/10.1016/j.toxlet.2011.01.029openalex-snapshot
T-2 toxin induces apoptosis in ovarian granulosa cells of rats through reactive oxygen species-mediated mitochondrial pathway
inferredcites →https://doi.org/10.1016/j.tvjl.2009.09.020openalex-snapshot
Effects of fusariotoxins in the equine species
inferredcites →https://doi.org/10.1016/s0021-9258(19)52451-6openalex-snapshot
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
inferredcites →https://doi.org/10.1016/s1382-6689(02)00020-0openalex-snapshot
Cytotoxicity assays for mycotoxins produced by Fusarium strains: a review
inferredcites →https://doi.org/10.1021/jf00066a017openalex-snapshot
Glucuronide conjugates of T-2 toxin and metabolites in swine bile and urine
inferredcites →https://doi.org/10.1021/jf00070a026openalex-snapshot
Deepoxy T-2 tetraol: a metabolite of T-2 toxin found in cow urine
inferredcites →https://doi.org/10.1021/jf200767qopenalex-snapshot
T-2 Toxin, a Trichothecene Mycotoxin: Review of Toxicity, Metabolism, and Analytical Methods
inferredcites →https://doi.org/10.1021/jf300634kopenalex-snapshot
Identification and Apoptotic Potential of T-2 Toxin Metabolites in Human Cells
inferredcites →https://doi.org/10.1021/jf302571yopenalex-snapshot
HT-2 Toxin 4-Glucuronide as New T-2 Toxin Metabolite: Enzymatic Synthesis, Analysis, and Species Specific Formation of T-2 and HT-2 Toxin Glucuronides by Rat, Mouse, Pig, and Human Liver Microsomes
inferredcites →https://doi.org/10.1080/02652030110046901openalex-snapshot
Occurrence of T-2 toxin in processed cereals and pulses in Turkey determined by HPLC and TLC
inferredcites →https://doi.org/10.1080/02652030118172openalex-snapshot
Occurrence of T-2 toxin in processed cereals and pulses in Turkey determined by HPLC and TLC
inferredcites →https://doi.org/10.1080/03602530903125807openalex-snapshot
Metabolic pathways of trichothecenes
inferredcites →https://doi.org/10.1093/oxfordjournals.jbchem.a131854openalex-snapshot
Metabolism of Trichothecene Mycotoxins
inferredcites →https://doi.org/10.1128/aem.27.2.423-424.1974openalex-snapshot
In Vitro Metabolism of T-2 Toxin
inferredcites →https://doi.org/10.1128/aem.39.6.1172-1177.1980openalex-snapshot
T-2 metabolites in the excreta of broiler chickens administered 3H-labeled T-2 toxin
inferredcites →https://doi.org/10.1128/aem.40.5.901-906.1980openalex-snapshot
In vitro metabolism of T-2 toxin in rats
inferredcites →https://doi.org/10.1128/aem.47.1.130-134.1984openalex-snapshot
In vitro formation of 3'-hydroxy T-2 and 3'-hydroxy HT-2 toxins from T-2 toxin by liver homogenates from mice and monkeys
inferredcites →https://doi.org/10.1128/aem.49.5.1246-1250.1985openalex-snapshot
Identification of various T-2 toxin metabolites in chicken excreta and tissues
inferredcites →https://doi.org/10.1128/aem.50.3.676-679.1985openalex-snapshot
Structures of deepoxytrichothecene metabolites from 3'-hydroxy HT-2 toxin and T-2 tetraol in rats
inferredcites →https://doi.org/10.1128/cmr.16.3.497-516.2003openalex-snapshot
Mycotoxins
inferredcites →https://doi.org/10.1177/0748233709354554openalex-snapshot
Toxic effects of T-2 toxin on reproductive system in male mice
inferredcites →https://doi.org/10.2903/j.efsa.2011.2481openalex-snapshot
Scientific Opinion on the risks for animal and public health related to the presence of T‐2 and HT‐2 toxin in food and feed
inferredcites →https://doi.org/10.3109/00498254.2011.593206openalex-snapshot
A comparison of hepaticin vitrometabolism of T-2 toxin in rats, pigs, chickens, and carp
inferredcites →https://doi.org/10.3109/03602530903125807openalex-snapshot
Metabolic pathways of trichothecenes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Efficient Killing of Multidrug‐Resistant Internalized Bacteria by AIEgens In Vivo
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Metabolism of Mycotoxins and the Potential Biomarkers for Risk Assessment
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Oxidative stress-mediated cytotoxicity and metabolism of T-2 toxin and deoxynivalenol in animals and humans: an update
inferred← citeshttps://doi.org/10.1007/s00204-018-2267-zopenalex-snapshot
Deglucosylation of zearalenone-14-glucoside in animals and human liver leads to underestimation of exposure to zearalenone in humans
inferred← citeshttps://doi.org/10.1007/s00204-019-02577-5openalex-snapshot
T-2 toxin neurotoxicity: role of oxidative stress and mitochondrial dysfunction
inferred← citeshttps://doi.org/10.1007/s00204-020-02899-9openalex-snapshot
An update on T-2 toxin and its modified forms: metabolism, immunotoxicity mechanism, and human exposure assessment
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In vitro and in vivo metabolism of ochratoxin A: a comparative study using ultra-performance liquid chromatography-quadrupole/time-of-flight hybrid mass spectrometry
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Unraveling the in vitro and in vivo metabolism of diacetoxyscirpenol in various animal species and human using ultrahigh-performance liquid chromatography-quadrupole/time-of-flight hybrid mass spectrometry
inferred← citeshttps://doi.org/10.1007/s12550-025-00612-2openalex-snapshot
Human biomonitoring of mycotoxins: key challenges and future directions
inferred← citeshttps://doi.org/10.1016/b978-0-12-805393-5.00029-4openalex-snapshot
Ultra-high performance liquid chromatography
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Chlorine disinfection byproduct of diazepam affects nervous system function and possesses gender-related difference in zebrafish
inferred← citeshttps://doi.org/10.1016/j.fbio.2023.102663openalex-snapshot
Cytochrome P450 mediates the formation of four new citrinin metabolites
inferred← citeshttps://doi.org/10.1016/j.fbio.2026.109729openalex-snapshot
Ancestral reconstruction of fungal laccases enables broad-spectrum detoxification of co-occurring mycotoxins: Product identification, cytotoxicity assessment, and wheat matrix application
inferred← citeshttps://doi.org/10.1016/j.fct.2015.02.005openalex-snapshot
In vivo toxicity studies of fusarium mycotoxins in the last decade: A review
inferred← citeshttps://doi.org/10.1016/j.fct.2022.113262openalex-snapshot
T-2 toxin and its cardiotoxicity: New insights on the molecular mechanisms and therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.fct.2025.115491openalex-snapshot
Exploring the relationship between daily intake and urinary excretion of the mycotoxins T-2 and HT-2 toxin in humans
inferred← citeshttps://doi.org/10.1016/j.fct.2026.116132openalex-snapshot
Unraveling the toxicokinetics of the mycotoxins T-2 and HT-2 toxin in humans for developing a physiologically-based kinetic model
inferred← citeshttps://doi.org/10.1016/j.jpba.2015.02.048openalex-snapshot
Comparative metabolism of Lappaconitine in rat and human liver microsomes and in vivo of rat using ultra high-performance liquid chromatography–quadrupole/time-of-flight mass spectrometry
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Pathological consequences, metabolism and toxic effects of trichothecene T-2 toxin in poultry
inferred← citeshttps://doi.org/10.1016/j.taap.2024.117084openalex-snapshot
SIRT5 safeguards against T-2 toxin induced liver injury by repressing iron accumulation, oxidative stress, and the activation of NLRP3 inflammasome
inferred← citeshttps://doi.org/10.1016/j.talanta.2024.125971openalex-snapshot
Electrochemical microfluidic immunosensor with graphene-decorated gold nanoporous for T-2 mycotoxin detection
inferred← citeshttps://doi.org/10.1016/j.toxrep.2014.12.010openalex-snapshot
Comparison of anorectic potencies of the trichothecenes T-2 toxin, HT-2 toxin and satratoxin G to the ipecac alkaloid emetine
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Review of the Protective Effects of Selenium against T-2 Toxin-Induced Toxicity
inferred← citeshttps://doi.org/10.1021/acs.jafc.5b03281openalex-snapshot
Simultaneous Determination of Type A and B Trichothecenes and Their Main Metabolites in Food Animal Tissues by Ultraperformance Liquid Chromatography Coupled with Triple-Quadrupole Mass Spectrometry
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Comprehensive Analysis of Tiamulin Metabolites in Various Species of Farm Animals Using Ultra-High-Performance Liquid Chromatography Coupled to Quadrupole/Time-of-Flight
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Metabolism of T-2 Toxin in Farm Animals and Human In Vitro and in Chickens In Vivo Using Ultra High-Performance Liquid Chromatography- Quadrupole/Time-of-Flight Hybrid Mass Spectrometry Along with Online Hydrogen/Deuterium Exchange Technique
inferred← citeshttps://doi.org/10.1021/acs.jafc.8b02893openalex-snapshot
Toxicokinetics of HT-2 Toxin in Rats and Its Metabolic Profile in Livestock and Human Liver Microsomes
inferred← citeshttps://doi.org/10.1021/jf5012402openalex-snapshot
In Vitro and in Vivo Metabolite Profiling of Valnemulin Using Ultraperformance Liquid Chromatography–Quadrupole/Time-of-Flight Hybrid Mass Spectrometry
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Ultra-high performance liquid chromatography coupled with time-of-flight mass spectrometry screening and analysis of potential bioactive compounds from traditional chinese medicine Kai-Xin-San, using a multivariate data processing approach and the MetaboLynx tool
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Mycotoxin Biomarkers of Exposure: A Comprehensive Review
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Appropriateness to set a group health based guidance value for T2 and HT2 toxin and its modified forms
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Risk to human and animal health related to the presence of 4,15‐diacetoxyscirpenol in food and feed
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A biochemical, theoretical and immunohistochemical study comparing the therapeutic efficacy of curcumin and taurine on T-2 toxin induced hepatotoxicity in rats
inferred← citeshttps://doi.org/10.3389/fnut.2022.935112openalex-snapshot
Fluorine impairs carboxylesterase 1-mediated hydrolysis of T-2 toxin and increases its chondrocyte toxicity
inferred← citeshttps://doi.org/10.3390/foods13101501openalex-snapshot
Identification of Biotransformation Products of T-2 Toxin in HepG2 Cells Using LC-Q-TOF MS
inferred← citeshttps://doi.org/10.3390/microorganisms11030574openalex-snapshot
Evaluation of Effectiveness of a Novel Multicomponent Mycotoxins Detoxification Agent in the Presence of AFB1 and T-2 Toxin on Broiler Chicks
inferred← citeshttps://doi.org/10.3390/molecules26226868openalex-snapshot
T-2 Toxin—The Most Toxic Trichothecene Mycotoxin: Metabolism, Toxicity, and Decontamination Strategies
inferred← citeshttps://doi.org/10.3390/toxins10050179openalex-snapshot
Comparison of Anorectic Potencies of Type A Trichothecenes T-2 Toxin, HT-2 Toxin, Diacetoxyscirpenol, and Neosolaniol
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Characterization of Phase I and Glucuronide Phase II Metabolites of 17 Mycotoxins Using Liquid Chromatography—High-Resolution Mass Spectrometry
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Cellular Effects of T-2 Toxin on Primary Hepatic Cell Culture Models of Chickens
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Antidotal Potency of the Novel, Structurally Different Adsorbents in Rats Acutely Intoxicated with the T-2 Toxin
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Human Biomonitoring of T-2 Toxin, T-2 Toxin-3-Glucoside and Their Metabolites in Urine through High-Resolution Mass Spectrometry
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Metabolic profile of the masked mycotoxin T-2 toxin-3-glucoside in rats (in vitro andin vivo) and humans (in vitro)
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Genotoxic Effects of Mycotoxins: Review
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