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Quercetin and Its In Vivo Metabolites Inhibit Neutrophil-Mediated Low-Density Lipoprotein Oxidation

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bio.772openalex-snapshot
Scavenger effect of flavonols on HOCl‐induced luminol chemiluminescence
inferredcites →https://doi.org/10.1002/biof.5520240106openalex-snapshot
Myeloperoxidase‐induced lipid peroxidation of LDL in the presence of nitrite. Protection by cocoa flavanols
inferredcites →https://doi.org/10.1002/jsfa.2675openalex-snapshot
Dietary flavonoids: effects on endothelial function and blood pressure
inferredcites →https://doi.org/10.1006/abbi.2001.2562openalex-snapshot
Effects of Flavonols on the Generation of Superoxide Anion Radicals by Xanthine Oxidase and Stimulated Neutrophils
inferredcites →https://doi.org/10.1006/abio.1998.3037openalex-snapshot
An Improved Method for the Measurement of Urinary and Plasma F2-Isoprostanes Using Gas Chromatography–Mass Spectrometry
inferredcites →https://doi.org/10.1007/bf01940544openalex-snapshot
Human myeloperoxidase activity is inhibited in vitro by quercetin. Comparison with three related compounds
inferredcites →https://doi.org/10.1016/j.amjcard.2007.04.039openalex-snapshot
Endotoxemia, Inflammation, and Atrial Fibrillation
inferredcites →https://doi.org/10.1016/j.chemphyslip.2004.02.001openalex-snapshot
Inhibition of human low density lipoprotein oxidation by flavonols and their glycosides
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2007.09.017openalex-snapshot
Myricitrin as a substrate and inhibitor of myeloperoxidase: Implications for the pharmacological effects of flavonoids
inferredcites →https://doi.org/10.1016/j.jacc.2007.02.040openalex-snapshot
Plasma Concentrations of Myeloperoxidase Predict Mortality After Myocardial Infarction
inferredcites →https://doi.org/10.1016/j.niox.2006.04.264openalex-snapshot
Elevated circulating levels of markers of oxidative-nitrative stress and inflammation in a genetic rat model of metabolic syndrome
inferredcites →https://doi.org/10.1016/j.tet.2006.04.102openalex-snapshot
Convenient syntheses of metabolically important quercetin glucuronides and sulfates
inferredcites →https://doi.org/10.1016/s0014-5793(03)00113-3openalex-snapshot
Myeloperoxidase/nitrite‐mediated lipid peroxidation of low‐density lipoprotein as modulated by flavonoids
inferredcites →https://doi.org/10.1016/s0031-9422(02)00445-4openalex-snapshot
Inhibition of LDL oxidation by flavonoids in relation to their structure and calculated enthalpy
inferredcites →https://doi.org/10.1016/s0076-6879(84)05049-7openalex-snapshot
[46] Measurement of O2− secreted by monocytes and macrophages
inferredcites →https://doi.org/10.1016/s0076-6879(84)05055-2openalex-snapshot
[52] Antimicrobial activity of myeloperoxidase
inferredcites →https://doi.org/10.1038/nm1637openalex-snapshot
Protein carbamylation links inflammation, smoking, uremia and atherogenesis
inferredcites →https://doi.org/10.1056/nejmoa035003openalex-snapshot
Prognostic Value of Myeloperoxidase in Patients with Chest Pain
inferredcites →https://doi.org/10.1074/jbc.272.3.1433openalex-snapshot
Reactive Nitrogen Intermediates Promote Low Density Lipoprotein Oxidation in Human Atherosclerotic Intima
inferredcites →https://doi.org/10.1074/jbc.m112400200openalex-snapshot
A Tale of Two Controversies
inferredcites →https://doi.org/10.1074/jbc.m606804200openalex-snapshot
Dietary Flavonoids Attenuate Tumor Necrosis Factor α-induced Adhesion Molecule Expression in Human Aortic Endothelial Cells
inferredcites →https://doi.org/10.1074/jbc.m706571200openalex-snapshot
Macrophage as a Target of Quercetin Glucuronides in Human Atherosclerotic Arteries
inferredcites →https://doi.org/10.1080/10715760400003384openalex-snapshot
Protection by Flavonoids Against the Peroxynitrite-mediated Oxidation of Dihydrorhodamine
inferredcites →https://doi.org/10.1093/ajcn/79.1.54openalex-snapshot
Red wine polyphenolic compounds inhibit atherosclerosis in apolipoprotein E–deficient mice independently of effects on lipid peroxidation
inferredcites →https://doi.org/10.1093/ajcn/79.5.727openalex-snapshot
Polyphenols: food sources and bioavailability
inferredcites →https://doi.org/10.1093/ajcn/80.1.15openalex-snapshot
How should we assess the effects of exposure to dietary polyphenols in vitro?
inferredcites →https://doi.org/10.1093/ajcn/81.1.230sopenalex-snapshot
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
inferredcites →https://doi.org/10.1093/ajcn/81.1.268sopenalex-snapshot
Health promotion by flavonoids, tocopherols, tocotrienols, and other phenols: direct or indirect effects? Antioxidant or not?
inferredcites →https://doi.org/10.1093/ajcn/81.1.292sopenalex-snapshot
Polyphenols and cardiovascular disease: effects on endothelial and platelet function
inferredcites →https://doi.org/10.1093/ajcn/81.1.317sopenalex-snapshot
Polyphenols and disease risk in epidemiologic studies
inferredcites →https://doi.org/10.1097/00000374-200103000-00017openalex-snapshot
Enhanced Antioxidant Activity After Chlorination of Quercetin by Hypochlorous Acid
inferredcites →https://doi.org/10.1097/00041433-200202000-00007openalex-snapshot
Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for cardiovascular health
inferredcites →https://doi.org/10.1097/01.mol.0000245255.40634.b5openalex-snapshot
Clinical applications of circulating oxidized low-density lipoprotein biomarkers in cardiovascular disease
inferredcites →https://doi.org/10.1152/physrev.00047.2003openalex-snapshot
Role of Oxidative Modifications in Atherosclerosis
inferredcites →https://doi.org/10.1161/01.cir.0000090690.67322.51openalex-snapshot
Myeloperoxidase Serum Levels Predict Risk in Patients With Acute Coronary Syndromes
inferredcites →https://doi.org/10.1182/blood.v99.5.1802.h8001802_1802_1810openalex-snapshot
Defects in leukocyte-mediated initiation of lipid peroxidation in plasma as studied in myeloperoxidase-deficient subjects: systematic identification of multiple endogenous diffusible substrates for myeloperoxidase in plasma
inferredcites →https://doi.org/10.1373/clinchem.2006.076992openalex-snapshot
Effects of α-Tocopherol and Mixed Tocopherol Supplementation on Markers of Oxidative Stress and Inflammation in Type 2 Diabetes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.12.016zenodo-depositor-declared
Metabolomics as a complement to phylogenetics for assessing intraspecific boundaries in the desiccation-tolerant medicinal shrub Myrothamnus flabellifolia (Myrothamnaceae)
inferred← citeshttps://doi.org/10.1002/9780470531792.ch5openalex-snapshot
The Biochemistry Behind the Potential Cardiovascular Protection by Dietary Flavonoids
inferred← citeshttps://doi.org/10.1002/9781118883303.ch1openalex-snapshot
The Physical Chemistry of Polyphenols
inferred← citeshttps://doi.org/10.1007/164_2020_388openalex-snapshot
Inhibition of Myeloperoxidase
inferred← citeshttps://doi.org/10.1007/978-3-032-27324-6_9openalex-snapshot
Polyphenols-Rich Functional Foods. Current Claims and Regulatory Perspectives
inferred← citeshttps://doi.org/10.1007/s00210-014-0995-zopenalex-snapshot
Oral administration of quercetin is unable to protect against isoproterenol cardiotoxicity
inferred← citeshttps://doi.org/10.1007/s10616-025-00788-6openalex-snapshot
Cell-based evaluation of anti-inflammatory activity from the combination of natural compounds in LPS-stimulated U937 monocytes
inferred← citeshttps://doi.org/10.1007/s10886-025-01614-1openalex-snapshot
The Effect of Plant Quercetin on Immune Function of Microtus Fortis
inferred← citeshttps://doi.org/10.1007/s11356-016-8108-9openalex-snapshot
Protective role of quercetin against hematotoxic and immunotoxic effects of furan in rats
inferred← citeshttps://doi.org/10.1007/s12013-025-01719-0openalex-snapshot
Determination of the Inhibitory Potential of Chalcones on Myeloperoxidase Enzyme Activity: In vitro and Molecular Docking Studies
inferred← citeshttps://doi.org/10.1007/s12192-015-0613-0openalex-snapshot
Crocin and Quercetin protect HCT116 and HEK293 cells from Zearalenone-induced apoptosis by reducing endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.1007/s12192-015-0651-7openalex-snapshot
Quercetin protects HCT116 cells from Dichlorvos-induced oxidative stress and apoptosis
inferred← citeshttps://doi.org/10.1007/s13668-015-0137-3openalex-snapshot
The Efficacy of Quercetin in Cardiovascular Health
inferred← citeshttps://doi.org/10.1016/j.arabjc.2021.103191openalex-snapshot
Quercetin attenuates cisplatin-induced ovarian toxicity in rats: Emphasis on anti-oxidant, anti-inflammatory and anti-apoptotic activities
inferred← citeshttps://doi.org/10.1016/j.bbagen.2018.04.007openalex-snapshot
Interference of carbidopa and other catechols with reactions catalyzed by peroxidases
inferred← citeshttps://doi.org/10.1016/j.bcp.2015.03.005openalex-snapshot
MK571 inhibits phase-2 conjugation of flavonols by Caco-2/TC7 cells, but does not specifically inhibit their apical efflux
inferred← citeshttps://doi.org/10.1016/j.bmcl.2018.11.031openalex-snapshot
The development of myeloperoxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejphar.2012.06.018openalex-snapshot
Quercetin, a flavonoid with anti-inflammatory activity, suppresses the development of abdominal aortic aneurysms in mice
inferred← citeshttps://doi.org/10.1016/j.foodchem.2009.09.031openalex-snapshot
Phenolic compounds from the leaves of Cyclocarya paliurus (Batal.) Ijinskaja and their inhibitory activity against PTP1B
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2012.06.010openalex-snapshot
Quercetin as a prophylactic measure against high altitude cerebral edema
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2010.02.008openalex-snapshot
Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155
inferred← citeshttps://doi.org/10.1016/j.nutres.2017.12.002openalex-snapshot
Chronic consumption of quercetin reduces erythrocytes oxidative damage: Evaluation at resting and after eccentric exercise in humans
inferred← citeshttps://doi.org/10.1016/j.nutres.2018.10.006openalex-snapshot
Estimation of daily intake of flavonoids and major food sources in middle-aged Australian men and women
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2020.107685openalex-snapshot
Myeloperoxidase: Mechanisms, reactions and inhibition as a therapeutic strategy in inflammatory diseases
inferred← citeshttps://doi.org/10.1016/j.saa.2009.05.004openalex-snapshot
Effect of the glycosylation of flavonoids on interaction with protein
inferred← citeshttps://doi.org/10.1016/j.snb.2023.133629openalex-snapshot
Site-specific cleavage-based chemiluminescent optical fiber biosensor for highly sensitive assay of myeloperoxidase activity and inhibitor screening
inferred← citeshttps://doi.org/10.1016/j.tifs.2018.11.026openalex-snapshot
A review on advanced microencapsulation technology to enhance bioavailability of phenolic compounds: Based on its activity in the treatment of Type 2 Diabetes
inferred← citeshttps://doi.org/10.1016/j.yexcr.2020.112320openalex-snapshot
NET-associated citrullinated histones promote LDL aggregation and foam cell formation in vitro
inferred← citeshttps://doi.org/10.1017/s0007114509359127openalex-snapshot
Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study
inferred← citeshttps://doi.org/10.1017/s0007114512003972openalex-snapshot
Dose–response to 3 months of quercetin-containing supplements on metabolite and quercetin conjugate profile in adults
inferred← citeshttps://doi.org/10.1017/s0029665112000249openalex-snapshot
ApoE genotype: from geographic distribution to function and responsiveness to dietary factors
inferred← citeshttps://doi.org/10.1017/s095442240926402xopenalex-snapshot
When nutrition interacts with osteoblast function: molecular mechanisms of polyphenols
inferred← citeshttps://doi.org/10.1021/acs.jafc.9b01782openalex-snapshot
An Innovative Approach to the Preparation of Plasma Samples for UHPLC–MS Analysis
inferred← citeshttps://doi.org/10.1021/jf402511copenalex-snapshot
Human Metabolic Transformation of Quercetin Blocks Its Capacity To Decrease Endothelial Nitric Oxide Synthase (eNOS) Expression and Endothelin-1 Secretion by Human Endothelial Cells
inferred← citeshttps://doi.org/10.1021/jp208731gopenalex-snapshot
Positioning of Antioxidant Quercetin and Its Metabolites in Lipid Bilayer Membranes: Implication for Their Lipid-Peroxidation Inhibition
inferred← citeshttps://doi.org/10.1038/s41598-018-19585-7openalex-snapshot
Hemoglobin catalyzes CoA degradation and thiol addition to flavonoids
inferred← citeshttps://doi.org/10.1039/c0fo00106fopenalex-snapshot
Conjugated quercetin glucuronides as bioactive metabolites and precursors of aglyconein vivo
inferred← citeshttps://doi.org/10.1039/c2fo30065fopenalex-snapshot
A state-of-the-art overview of the effect of metabolic conjugation on the biological activity of flavonoids
inferred← citeshttps://doi.org/10.1039/c4fo00413bopenalex-snapshot
The pleiotropic flavonoid quercetin: from its metabolism to the inhibition of protein kinases in chronic lymphocytic leukemia
inferred← citeshttps://doi.org/10.1080/10408390903584094openalex-snapshot
Effects of Flavonoids and other Polyphenols on Inflammation
inferred← citeshttps://doi.org/10.1080/10408398.2023.2299329openalex-snapshot
A critical examination of human data for the biological activity of quercetin and its phase-2 conjugates
inferred← citeshttps://doi.org/10.1080/14728222.2020.1762177openalex-snapshot
Myeloperoxidase: a potential therapeutic target for coronary artery disease
inferred← citeshttps://doi.org/10.1089/ars.2012.4581openalex-snapshot
Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases
inferred← citeshttps://doi.org/10.1097/mco.0b013e32831394b8openalex-snapshot
Quercetin: potentials in the prevention and therapy of disease
inferred← citeshttps://doi.org/10.1146/annurev.food.102308.124120openalex-snapshot
An Update on the Health Effects of Tomato Lycopene
inferred← citeshttps://doi.org/10.1155/2015/815210openalex-snapshot
Quercetin Increases Hepatic Homocysteine Remethylation and Transsulfuration in Rats Fed a Methionine-Enriched Diet
inferred← citeshttps://doi.org/10.1201/b17442openalex-snapshot
Antioxidants in Sport Nutrition
inferred← citeshttps://doi.org/10.1201/b17442-10openalex-snapshot
Evaluation of Quercetin as a Countermeasure to Exercise-Induced Physiological Stress
inferred← citeshttps://doi.org/10.1249/mss.0b013e318199491fopenalex-snapshot
Effects of Quercetin and EGCG on Mitochondrial Biogenesis and Immunity
inferred← citeshttps://doi.org/10.12688/f1000research.133905.1openalex-snapshot
Total cholesterol effect after consumption of tomato juice alone and in combination with extra virgin olive oil. A nine-day pilot study in hypercholesterolemic patients
inferred← citeshttps://doi.org/10.1271/bbb.90253openalex-snapshot
Clarification of the Role of Quercetin Hydroxyl Groups in Superoxide Generation and Cell Apoptosis by Chemical Modification
inferred← citeshttps://doi.org/10.2131/jts.38.25openalex-snapshot
Effect of quercetin and desferrioxamine on 6-hydroxydopamine (6-OHDA) induced neurotoxicity in striatum of rats
inferred← citeshttps://doi.org/10.2147/ott.s136821openalex-snapshot
Low concentration of quercetin antagonizes the invasion and angiogenesis of human glioblastoma U251 cells
inferred← citeshttps://doi.org/10.2174/1389557519666191009152007openalex-snapshot
Quercetin-Amino Acid Conjugates are Promising Anti-Cancer Agents in Drug Discovery Projects
inferred← citeshttps://doi.org/10.2174/1876396001205010193openalex-snapshot
Studies on Mechanistic Role of Natural Bioactive Compounds in the Management of Obesity An Overview
inferred← citeshttps://doi.org/10.3109/10715760903407293openalex-snapshot
Quercetin supplementation does not alter antioxidant status in humans
inferred← citeshttps://doi.org/10.31459/turkjkin.851832openalex-snapshot
Moringa protein drink increases testosterone and anabolic status of men with hyperlipidemia: A randomized controlled study
inferred← citeshttps://doi.org/10.3164/jcbn.11-006fropenalex-snapshot
Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention
inferred← citeshttps://doi.org/10.31665/jfb.2020.13259openalex-snapshot
Sugar, vitamin C, and polyphenols in commercial apple beverages and their effects on antioxidant and anti-inflammatory activities in vitro
inferred← citeshttps://doi.org/10.3389/fendo.2021.745959openalex-snapshot
Quercetin Modulates IGF-I and IGF-II Levels After Eccentric Exercise-Induced Muscle-Damage: A Placebo-Controlled Study
inferred← citeshttps://doi.org/10.3389/fnut.2022.875319openalex-snapshot
Short-Term Oral Quercetin Supplementation Improves Post-exercise Insulin Sensitivity, Antioxidant Capacity and Enhances Subsequent Cycling Time to Exhaustion in Healthy Adults: A Pilot Study
inferred← citeshttps://doi.org/10.3389/fphar.2022.854249openalex-snapshot
Neuroprotective Effects of Quercetin on Ischemic Stroke: A Literature Review
inferred← citeshttps://doi.org/10.3390/antiox12020258openalex-snapshot
Potential Role of Quercetin Glycosides as Anti-Atherosclerotic Food-Derived Factors for Human Health
inferred← citeshttps://doi.org/10.3390/antiox13080889openalex-snapshot
Role of Myeloperoxidase, Oxidative Stress, and Inflammation in Bronchopulmonary Dysplasia
inferred← citeshttps://doi.org/10.3390/ijms22020646openalex-snapshot
Iron Complexes of Flavonoids-Antioxidant Capacity and Beyond
inferred← citeshttps://doi.org/10.3390/ijms23158344openalex-snapshot
Effects of the Treatment with Flavonoids on Metabolic Syndrome Components in Humans: A Systematic Review Focusing on Mechanisms of Action
inferred← citeshttps://doi.org/10.3390/nu11010205openalex-snapshot
The Effects of Quercetin Supplementation on Eccentric Exercise-Induced Muscle Damage
inferred← citeshttps://doi.org/10.3390/nu14030658openalex-snapshot
Improving Lipophagy by Restoring Rab7 Cycle: Protective Effects of Quercetin on Ethanol-Induced Liver Steatosis
inferred← citeshttps://doi.org/10.3892/mmr.2013.1846openalex-snapshot
Quercetin reduces oxidative stress and inhibits activation of c-Jun N-terminal kinase/activator protein-1 signaling in an experimental mouse model of abdominal aortic aneurysm
inferred← citeshttps://doi.org/10.3906/biy-2104-16openalex-snapshot
Treatment of COVID-19 patients with quercetin: a prospective, single center, randomized, controlled trial
inferred← citeshttps://doi.org/10.3945/jn.109.117655openalex-snapshot
Serum Lipid and Blood Pressure Responses to Quercetin Vary in Overweight Patients by Apolipoprotein E Genotype
inferred← citeshttps://doi.org/10.61186/rbmb.13.2.184openalex-snapshot
Quercetin and Catechin Protects Leptin-Deficient Lepob/Ob Mice Against Alloxan-Induced Diabetes and Hepatotoxicity via Suppression of Oxidative Stress and Inflammation
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