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Synthesis and antibacterial activity of thiazolo-, oxazolo-, and imidazolo[3,2-a][1,8]naphthyridinecarboxylic acids

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inferred← citeshttps://doi.org/10.2139/ssrn.4798967openalex-extracted
Radical Cascade Reaction of Heterocyclic Ketene Aminals with Thiocyanates Promoted by Visible Light: Environmentally Fridendly Synthesis of Functionalized Fused 2-Iminothiazolines
inferred← citeshttps://doi.org/10.1002/adsc.202100320openalex-snapshot
Catalyst‐Free Electrophilic Ring Expansion of N ‐Unprotected Aziridines with α ‐Oxoketenes to Efficient Access 2‐Alkylidene‐1,3‐Oxazolidines
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Synthesis and Evaluation of 3‐Fluoro‐2‐piperazinyl‐5,8,13‐trihydro‐5‐oxoquino[1,2‐a][3,1]benzoxazine‐6‐carboxylic Acids as Potential Antibacterial Agents
inferred← citeshttps://doi.org/10.1002/ardp.201500237openalex-snapshot
1,8‐Naphthyridine Derivatives: A Review of Multiple Biological Activities
inferred← citeshttps://doi.org/10.1002/chin.199116180openalex-snapshot
ChemInform Abstract: Synthesis and Antibacterial Activity of Thiazolo‐, Oxazolo‐ and Imidazo(3,2‐a)(1,8)naphthyridinecarboxylic Acids.
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Three‐Component Synthesis of Indanone‐Fused Spirooxindole Derivatives
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Heterocyclic Ketene Aminals: Scaffolds for Heterocycle Molecular Diversity
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4‐Quinolone Derivatives and Their Activities Against Gram‐negative Pathogens
inferred← citeshttps://doi.org/10.1002/jhet.433openalex-snapshot
Synthesis and biological evaluation of novel 2‐(4‐ O ‐β‐ D ‐glucosidoxyphenyl)‐4,5‐disubstituted imidazoles
inferred← citeshttps://doi.org/10.1002/jhet.5570310126openalex-snapshot
Synthesis of some novel fused tetracyclic quinolonecarboxylic acids via 7‐methyl‐6,7,8,9‐tetrahydro‐3H‐imidazo[4,5‐f]quinoline and 6‐methyl‐5,6,7,8‐tetrahydro‐1H‐imidazo[4,5‐g]quinoline
inferred← citeshttps://doi.org/10.1002/jhet.5570390608openalex-snapshot
Synthesis of novel fused tricyclic quinolones: 4a,5‐Dihydro‐1H‐[1;2,4]triazino[1,6‐a]quinoline‐2,4,6(3H)‐triones
inferred← citeshttps://doi.org/10.1002/prac.19933350502openalex-snapshot
Zur Bedeutung des Cycloaracylierungsverfahrens f�r die Synthese moderner Fluorchinolone
inferred← citeshttps://doi.org/10.1007/978-3-642-80364-2_2openalex-snapshot
The Chemistry of the Quinolones: Methods of Synthesizing the Quinolone Ring System
inferred← citeshttps://doi.org/10.1007/bf02226387openalex-snapshot
Relationship between structure and antibacterial activity in the fluoroquinolone series of compounds
inferred← citeshttps://doi.org/10.1007/s10593-007-0156-0openalex-snapshot
4-hydroxy-2-quinolones. 124. Synthesis and structure of ethyl 2-bromomethyl-5-oxo-1,2,6,7,8,9-hexahydro-5H-oxazolo-[3,2-a]quinoline-4-carboxylate
inferred← citeshttps://doi.org/10.1007/s11172-005-0312-6openalex-snapshot
Polyfluorobenzoyl chlorides and isothiocyanates in reactions with CH-reactive benzimidazoles
inferred← citeshttps://doi.org/10.1007/s11178-006-0017-9openalex-snapshot
Fluoro-containing Heterocycles: XIII. Fluoro-containing Derivatives of Thiazolo[3,2-a]-, Benzothiazolo[3,2-a]-, and Benzimidazo[3,2-a]quinazolinones
inferred← citeshttps://doi.org/10.1016/0040-4020(96)00415-2openalex-snapshot
A novel synthesis of the pyrazolo[1,5-a]quinoline ring system. New N1-C2 bridged DNA gyrase inhibitors via a novel tandem 1,4-conjugate addition-Michael [3+2] annulation process
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.02.051openalex-snapshot
Isoindolin-1-one derivatives as urease inhibitors: Design, synthesis, biological evaluation, molecular docking and in-silico ADME evaluation
inferred← citeshttps://doi.org/10.1016/j.bmc.2007.11.016openalex-snapshot
Antimycobacterial activities of novel 2-(sub)-3-fluoro/nitro-5,12-dihydro-5-oxobenzothiazolo[3,2-a]quinoline-6-carboxylic acid
inferred← citeshttps://doi.org/10.1016/j.bmcl.2009.11.044openalex-snapshot
Solvent-free, microwave assisted synthesis of polyhalo heterocyclic ketene aminals as novel anti-cancer agents
inferred← citeshttps://doi.org/10.1016/j.cclet.2014.09.018openalex-snapshot
A novel and facile synthesis of 2-oxo-1,2-dihydropyridine-fused 1,3-diazaheterocycles via heterocyclic ketene aminals and Konevenagel adducts formed by phthalic anhydride and ethyl cyanacetate
inferred← citeshttps://doi.org/10.1016/j.ejmech.2011.01.036openalex-snapshot
Biological evaluation of polyhalo 1,3-diazaheterocycle fused isoquinolin-1(2H)-imine derivatives
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.08.095openalex-snapshot
Recent developments of quinolone-based derivatives and their activities against Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.gresc.2021.10.008openalex-snapshot
An environmentally benign multi-component reaction: Highly regioselective synthesis of functionalized 2-(diarylphosphoryl)-1,2-dihydro-pyridine derivatives
inferred← citeshttps://doi.org/10.1016/j.gresc.2022.10.014openalex-snapshot
Highly selective synthesis of functionalized morphan derivatives through a multi-component cascade reaction of 3-formylchromones, 2-naphthols, and enaminones
inferred← citeshttps://doi.org/10.1016/j.inoche.2011.10.037openalex-snapshot
DNA interaction and in-vitro antibacterial studies of fluoroquinolone based platinum(II) complexes
inferred← citeshttps://doi.org/10.1016/j.tet.2011.10.035openalex-snapshot
Synthesis of the novel pyrimido[1,6-a]pyrimidine and imidazo[1,2-c]pyrimidine derivatives based on heterocyclic ketene aminals
inferred← citeshttps://doi.org/10.1016/j.tet.2014.05.032openalex-snapshot
Palladium(II)-catalyzed cyclization of heterocyclic ketene aminals with (E)-ethyl 2,3-diiodoacrylates: selective synthesis of bicyclic pyrroles and bicyclic pyridones
inferred← citeshttps://doi.org/10.1016/j.tet.2014.07.017openalex-snapshot
Three-component cascade reaction synthesis of polycyclic 1,4-dihydropyridine derivatives in water
inferred← citeshttps://doi.org/10.1016/j.tet.2015.03.006openalex-snapshot
Three-component solvent-free synthesis of fluorine substituted bicyclic pyridines
inferred← citeshttps://doi.org/10.1016/j.tet.2021.132275openalex-snapshot
Base-promoted relay reaction of heterocyclic ketene aminals with o-difluorobenzene derivatives for the highly site-selective synthesis of functionalized indoles
inferred← citeshttps://doi.org/10.1016/j.tetlet.2008.05.005openalex-snapshot
A novel and efficient synthesis of 3-carboxy-4-oxo-1,8-naphthyridines using magnesium chloride
inferred← citeshttps://doi.org/10.1016/s0065-2725(06)91004-6openalex-snapshot
Advances in the Chemistry of Naphthyridines
inferred← citeshttps://doi.org/10.1016/s0968-0896(97)00084-9openalex-snapshot
Synthesis and antibacterial evaluation of [1,3]benzothiazino[3,2-a]quinoline- and [3,1]benzothiazino[1,2-a]quinoline-6-carboxylic acid derivatives
inferred← citeshttps://doi.org/10.1016/s1386-1425(99)00200-0openalex-snapshot
Effect of solvents on the photophysical properties of substituted imidazonaphthyridine derivatives
inferred← citeshttps://doi.org/10.1021/acs.joc.1c00211openalex-snapshot
An Environmentally Benign Cascade Reaction of 1,1-Enediamines (EDAMs) for Site-Selective Synthesis of Highly Functionalized 2,10-Dihydro-1H-imidazo[1′,2′:1,6]pyrido[2,3-b]indoles and Pyrroles
inferred← citeshttps://doi.org/10.1021/acs.joc.2c00695openalex-snapshot
An Environmentally Benign Multicomponent Cascade Reaction of 3-Formylchromones, 2-Naphthols, and Heterocyclic Ketal Aminals: Site-Selective Synthesis of Functionalized Morphan Derivatives
inferred← citeshttps://doi.org/10.1021/acs.joc.4c01899openalex-snapshot
Radical Cascade Reaction of Heterocyclic Ketene Aminals with Thiocyanates Promoted by Visible Light: Synthesis of Functionalized Fused 2-Iminothiazolines
inferred← citeshttps://doi.org/10.1021/acs.joc.5c00811openalex-snapshot
Fe-Catalyzed Radical Trifluoromethylation and Cyclization of Ortho-Vinyl Enaminones with 1-(Trifluoromethyl)-1,3-benzo-[d][1,2]iodaoxol-3(1H)-one to Construct Functionalized Quinolines
inferred← citeshttps://doi.org/10.1021/acs.joc.6c00397openalex-snapshot
Fe(III)-Mediated Oxidative [5 + 1] Cyclization for the Highly Site-Selective Synthesis of Functionalized Quinoline Derivatives
inferred← citeshttps://doi.org/10.1021/acs.joc.6c01340openalex-snapshot
Pd-Catalyzed Regioselective Phenoxyl-Arylation of Ynamides: An Access to Tetrasubstituted Ketene N,O -Acetals
inferred← citeshttps://doi.org/10.1021/acs.joc.8b00099openalex-snapshot
Three-Component Site-Selective Synthesis of Highly Substituted 5H-Chromeno-[4,3-b]pyridines
inferred← citeshttps://doi.org/10.1021/acs.joc.8b02594openalex-snapshot
Cascade Reaction of Morita–Baylis–Hillman Acetates with 1,1-Enediamines or Heterocyclic Ketene Aminals: Synthesis of Highly Functionalized 2-Aminopyrroles
inferred← citeshttps://doi.org/10.1021/acs.joc.9b01814openalex-snapshot
Multicomponent Tether Catalysis Synthesis of Highly Functionalized 4-(Pyridin-2-ylmethyl)-2-aminopyrroles via Cascade Reaction Is Accompanied by Decarboxylation
inferred← citeshttps://doi.org/10.1021/acs.joc.9b02063openalex-snapshot
Multicomponent Cascade Reaction by Metal-Free Aerobic Oxidation for Synthesis of Highly Functionalized 2-Amino-4-coumarinyl-5-arylpyrroles
inferred← citeshttps://doi.org/10.1021/acs.orglett.0c02689openalex-snapshot
Cu(II)/Iodine(III) Oxide Dimerization of Heterocyclic Ketene Aminals: Tandem TEMPO Oxidation for the Highly Selective Synthesis of Functionalized 2 H -Pyrrolo[1,2- a ]imidazol-7(3 H )-ones
inferred← citeshttps://doi.org/10.1021/acs.orglett.1c02431openalex-snapshot
Multicomponent Cascade Reaction of 3-Formylchromones: Highly Selective Synthesis of Functionalized 9-Azabicyclo[3.3.1]nonane Derivatives
inferred← citeshttps://doi.org/10.1021/acs.orglett.3c00095openalex-snapshot
Hydroxyl-Directed Rh(III)-Catalyzed C–H Functionalization: Access to Benzo[ de ]chromenes
inferred← citeshttps://doi.org/10.1021/acs.orglett.5c00174openalex-snapshot
Highly Stereoselective Synthesis of α-Oxoketene N,X-Acetals (X = O, S, or N) under Mild Conditions
inferred← citeshttps://doi.org/10.1021/acs.orglett.6c03339openalex-snapshot
Rh(III)-Catalyzed C–H Activation/[3 + 2] Cycloaddition for the Synthesis of Functionalized Pyrrolo[1,2- a ]imidazole Derivatives
inferred← citeshttps://doi.org/10.1021/acs.orglett.7b03803openalex-snapshot
Cascade Reaction of Isatins with 1,1-Enediamines: Synthesis of Multisubstituted Quinoline-4-carboxamides
inferred← citeshttps://doi.org/10.1021/acs.orglett.9b00518openalex-snapshot
Direct Access to α-Oxoketene Aminals via Copper-Catalyzed Formal Oxyaminalization of Alkenes under Mild Conditions
inferred← citeshttps://doi.org/10.1021/acsomega.7b01493openalex-snapshot
Diastereoselective Synthesis of Morphan Derivatives by Michael and Hetero-Michael Addition of 1,1-Enediamines to Quinone Monoketals
inferred← citeshttps://doi.org/10.1021/acsomega.7b01856openalex-snapshot
Facile Route to the Synthesis of 1,3-Diazahetero-Cycle-Fused [1,2- a ]Quinoline Derivatives via Cascade Reactions
inferred← citeshttps://doi.org/10.1021/cc900121copenalex-snapshot
Facile Route to 1,3-Diazaheterocycle-Fused [1,2b]Isoquinolin-1(2H)-one Derivatives via Substitution-Cyclization Reactions
inferred← citeshttps://doi.org/10.1021/ol201783dopenalex-snapshot
Cascade Reaction of Isatins with Heterocyclic Ketene Aminals: Synthesis of Imidazopyrroloquinoline Derivatives
inferred← citeshttps://doi.org/10.1023/b:rucb.0000042266.81755.0aopenalex-snapshot
Stabilization of [2.2]paracyclophane anion as a result of transannular interaction
inferred← citeshttps://doi.org/10.1038/s41598-022-18224-6openalex-snapshot
Design, synthesis, in silico and biological evaluations of novel polysubstituted pyrroles as selective acetylcholinesterase inhibitors against Alzheimer’s disease
inferred← citeshttps://doi.org/10.1038/s41598-022-18455-7openalex-snapshot
Design, synthesis, and in silico studies of quinoline-based-benzo[d]imidazole bearing different acetamide derivatives as potent α-glucosidase inhibitors
inferred← citeshttps://doi.org/10.1039/c3ra41547copenalex-snapshot
Three component solvent-free synthesis of 1H-pyrazol-5(4H)-one-based heterocyclic ketene aminal derivatives
inferred← citeshttps://doi.org/10.1039/c6ob01539eopenalex-snapshot
Palladium meets copper: one-pot tandem synthesis of pyrido fused heterocycles via Sonogashira conjoined electrophilic cyclization
inferred← citeshttps://doi.org/10.1039/c7gc01435jopenalex-snapshot
An environmentally benign double Michael addition reaction of heterocyclic ketene aminals with quinone monoketals for diastereoselective synthesis of highly functionalized morphan derivatives in water
inferred← citeshttps://doi.org/10.1039/d0cc00923gopenalex-snapshot
Cascade reaction of isatins with nitro-substituted enamines: highly selective synthesis of functionalized ( Z )-3-(1-(arylamino)-2-oxoarylidene)indolin-2-ones
inferred← citeshttps://doi.org/10.1039/d0qo00388copenalex-snapshot
Silver-catalyzed cascade reactions of 3-cyanochromone with 1,1-enediamines: synthesis of highly functionalized 2-(pyridin-3-yl)-chromeno[2,3- d ]pyrimidines
inferred← citeshttps://doi.org/10.1039/d1qo00666eopenalex-snapshot
Multicomponent cascade reactions of HKAs: synthesis of highly functionalized 5 H -chromeno[4,3- d ]pyrimidines
inferred← citeshttps://doi.org/10.1039/d2cc06388copenalex-snapshot
Synthesis of benzo[ b ][1,5]diazocin-6(5 H )-one derivatives via the Cu-catalysed oxidative cyclization of 2-aryl-1 H -indoles with 1,1-enediamines
inferred← citeshttps://doi.org/10.1039/d2ra05547copenalex-snapshot
Nitroenediamines (EDAMs), and N -methyl-1-(methylthio)-2-nitroethenamine (NMSM) derivatives: scaffolds for heterocycle molecular diversity (update from 2012 to 2021)
inferred← citeshttps://doi.org/10.1039/d3qo00685aopenalex-snapshot
Fe(OTf) 3 -catalyzed annulation of α,β-unsaturated ketoxime acetates with enaminones for the synthesis of functionalized 2,4-diarylpyridines
inferred← citeshttps://doi.org/10.1039/d6ob00288aopenalex-snapshot
Catalyst-free facile synthesis of 2-(dihydropyridyl)benzothiazoles from (benzothiazol-2-yl)acrylonitriles: green route
inferred← citeshttps://doi.org/10.1080/10426500008046608openalex-snapshot
ONE—POT SYNTHESIS OF PYRIDINES, THIENOPYRIDINES, PYRROLOTHIENOPYRIDINES AND (1,8) NAPHTHYRIDINES UNDER PHASE-TRANSFER CATALYSIS CONDITIONS
inferred← citeshttps://doi.org/10.1107/s160053680501144xopenalex-snapshot
1-(4-Methylpiperdinemethyl)-2-(4-bromophenyl)-6-methyl-8-trifluoromethylimidazo[1,2-a][1,8]naphthyridinium picrate
inferred← citeshttps://doi.org/10.1107/s160053680502547xopenalex-snapshot
1-Dimethylammoniomethyl-6,8-dimethyl-2-phenyl-1,2-dihydroimidazo[1,2-a][1,8]naphthyridine picrate monohydrate
inferred← citeshttps://doi.org/10.1107/s1600536805031272openalex-snapshot
1′-Methyl-4′,5-diphenyl-5,6,7,8,9,10-hexahydro-1,3-cycloheptapyrimidino[2,3-b]thiazole-2-spiro-3′-pyrrolidine-2′-spiro-3′′-1H-indole-2′′,3(2H,3′′H)-dione
inferred← citeshttps://doi.org/10.1107/s1600536807045072openalex-snapshot
3-(4-Methyl-1,3-thiazol-5-yl)-1-[1′-(4-methyl-1,3-thiazol-5-yl)-2-oxo-2,3,2′,3′,5′,6′,7′,7a′-octahydro-1H-indole-3-spiro-3'-1H-pyrrolizin-2′-yl]prop-2-en-1-one
inferred← citeshttps://doi.org/10.1107/s1600536809037544openalex-snapshot
10-Methoxybenzo[g]imidazo[1,2-a][1,8]naphthyridine-4-carbonitrile
inferred← citeshttps://doi.org/10.1107/s1600536813013858openalex-snapshot
1-(4-Chlorophenyl)-2-(1,3-diazepan-2-ylidene)ethanone
inferred← citeshttps://doi.org/10.2174/1874104502014010108openalex-snapshot
Synthesis of Medicinally Important Quinazolines and Their Derivatives: A Review
inferred← citeshttps://doi.org/10.3987/com-10-s(e)34openalex-snapshot
Reactions of Heterocyclic Ketene Aminals with Acrylonitrile: An Efficient Synthesis of Dihydropyridine-Fused 1,3-Diazaheterocycles
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