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5-HT4Receptor Ligands: Applications and New Prospects

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inferredcites →https://doi.org/10.1002/(sici)1098-1128(199703)17:2<163::aid-med2>3.0.co;2-yopenalex-snapshot
Serotonin 5-HT3 and 5-HT4 receptor antagonists
inferredcites →https://doi.org/10.1002/(sici)1098-2396(200004)36:1<35::aid-syn4>3.0.co;2-yopenalex-snapshot
Mapping of serotonin 5-HT4 receptor mRNA and ligand binding sites in the post-mortem human brain
inferredcites →https://doi.org/10.1002/chir.530040305openalex-snapshot
The resolution, isolation, and pharmacological characterization of the enantiomers of a benzamide containing a chiral sulfoxide
inferredcites →https://doi.org/10.1002/ddr.430260404openalex-snapshot
Gastrointestinal motility responses to the S and R enantiomers of zacopride, a 5‐HT4 agonist and 5‐HT3 antagonist
inferredcites →https://doi.org/10.1002/ddr.430330307openalex-snapshot
Potassium channel blockers as antiarrhythmic drugs
inferredcites →https://doi.org/10.1002/j.1460-2075.1995.tb07280.xopenalex-snapshot
The 5‐HT4 receptor: molecular cloning and pharmacological characterization of two splice variants.
inferredcites →https://doi.org/10.1002/j.1552-4604.1997.tb04785.xopenalex-snapshot
First Pharmacokinetic—Pharmacodynamic Study in Humans with a Selective 5‐Hydroxytryptamine4 Receptor Agonist
inferredcites →https://doi.org/10.1006/jsre.1994.1107openalex-snapshot
Evidence for a 5-HT4 Receptor Pathway Mediating Chloride Secretion in the Rat Distal Colon
inferredcites →https://doi.org/10.1006/phrs.1996.0030openalex-snapshot
RECENT ADVANCES IN THE PHARMACOLOGY OF GASTROINTESTINAL PROKINETICS
inferredcites →https://doi.org/10.1006/phrs.1998.0454openalex-snapshot
PHARMACOLOGICAL PROPERTIES OF A NOVEL GASTROINTESTINAL PROKINETIC BENZAMIDE SELECTIVE FOR HUMAN 5-HT4RECEPTORVERSUSHUMAN 5-HT3RECEPTOR
inferredcites →https://doi.org/10.1006/taap.1998.8494openalex-snapshot
Effects of Gastrointestinal Prokinetic Agents, TKS159 and Cisapride, on thein SituCanine Heart Assessed by Cardiohemodynamic and Electrophysiological Monitoring
inferredcites →https://doi.org/10.1007/978-3-0348-7259-1openalex-snapshot
Serotonin: Molecular Biology, Receptors and Functional Effects
inferredcites →https://doi.org/10.1007/978-3-662-05553-3_1openalex-snapshot
Medicinal Chemistry of 5-HT4 Receptor Ligands
inferredcites →https://doi.org/10.1007/bf00167041openalex-snapshot
The gastrointestinal prokinetic benzamide derivatives are agonists at the non-classical 5-HT receptor (5-HT4) positively coupled to adenylate cyclase in neurons
inferredcites →https://doi.org/10.1007/bf00168685openalex-snapshot
Characterization of a novel 5-HT4 receptor antagonist of the azabicycloalkyl benzimidazolone class: DAU 6285
inferredcites →https://doi.org/10.1007/bf00168686openalex-snapshot
Effects of 5-HT4 receptor stimulation on basal and electrically evoked release of acetylcholine from guinea-pig myenteric plexus
inferredcites →https://doi.org/10.1007/bf00168735openalex-snapshot
5-Hydroxytryptamine-induced increase in left ventricular dP/dtmax does not suggest the presence of ventricular 5-HT4 receptors in the pig
inferredcites →https://doi.org/10.1007/bf00170158openalex-snapshot
Investigation of the 5-hydroxytryptamine receptor mediating the ?transient? short-circuit current response in guinea-pig ileal mucosa
inferredcites →https://doi.org/10.1007/bf00171339openalex-snapshot
L-type calcium channel activity in human atrial myocytes as influenced by 5-HT
inferredcites →https://doi.org/10.1007/bf00176614openalex-snapshot
A 5-HT4-like receptor in human left atrium
inferredcites →https://doi.org/10.1007/bf00178965openalex-snapshot
5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum
inferredcites →https://doi.org/10.1007/bf00191172openalex-snapshot
A serotonergic mechanism for the metoclopramide-induced increase in aldosterone level?
inferredcites →https://doi.org/10.1007/bf00233241openalex-snapshot
Benzimidazolones and renzapride facilitate acetylcholine release from guinea-pig myenteric plexus via 5-HT4 receptors
inferredcites →https://doi.org/10.1007/bf01303162openalex-snapshot
U. S. Householder survey of functional gastrointestinal disorders
inferredcites →https://doi.org/10.1007/bf01395503openalex-snapshot
Irritable bowel syndrome
inferredcites →https://doi.org/10.1007/bf02802027openalex-snapshot
Review: Amino acid domains involved in constitutive activation of G-protein-coupled receptors
inferredcites →https://doi.org/10.1007/pl00005110openalex-snapshot
Facilitation of acetylcholine release in rat frontal cortex by indeloxazine hydrochloride: involvement of endogenous serotonin and 5-HT4 receptors
inferredcites →https://doi.org/10.1007/s002100000299openalex-snapshot
5-HT 4(a) and 5-HT 4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle
inferredcites →https://doi.org/10.1007/s002280050159openalex-snapshot
Lack of effect of the serotonin 4 receptor agonist zacopride on ACTH secretion in normal men
inferredcites →https://doi.org/10.1007/s003950170081openalex-snapshot
Atrial L-type Ca 2+ -channel, β-adrenoreceptor, and 5-hydroxytryptamine type 4 receptor mRNAs in human atrial fibrillation
inferredcites →https://doi.org/10.1007/s007020050080openalex-snapshot
Characterization of the 5-HT 4 binding site in human brain
inferredcites →https://doi.org/10.1016/0014-2999(88)90503-1openalex-snapshot
A 5-HT receptor in the central nervous system, positively coupled with adenylate cyclase, is antagonized by ICS 205 930
inferredcites →https://doi.org/10.1016/0014-2999(90)90041-4openalex-snapshot
Pharmacological and functional analysis of a novel serotonin receptor in the rat hippocampus
inferredcites →https://doi.org/10.1016/0014-2999(91)90421-lopenalex-snapshot
Identification of putative 5-HT4 receptors in guinea-pig ascending colon
inferredcites →https://doi.org/10.1016/0014-2999(92)90071-bopenalex-snapshot
Is the action of cisapride on the guinea-pig ileum mediated via 5-HT4 receptors?
inferredcites →https://doi.org/10.1016/0014-2999(92)90293-dopenalex-snapshot
5-HT4 receptors, present in piglet atria and sensitive to SDZ 205-557, are absent in papillary muscle
inferredcites →https://doi.org/10.1016/0014-2999(92)90333-yopenalex-snapshot
Benzimidazolone derivatives act as 5-HT4 receptor ligands in rat oesophagus
inferredcites →https://doi.org/10.1016/0014-2999(94)90219-4openalex-snapshot
Effect of a series of 5-HT4 receptor agonists and antagonists on steroid secretion by the adrenal gland in vitro
inferredcites →https://doi.org/10.1016/0014-2999(96)00122-7openalex-snapshot
[3H]5-Hydroxytryptamine labels the agonist high affinity state of the cloned rat 5-HT4 receptor
inferredcites →https://doi.org/10.1016/0014-2999(96)00457-8openalex-snapshot
Effects of 5-HT4 receptor antagonists on rat behaviour in the elevated plus-maze test
inferredcites →https://doi.org/10.1016/0016-5085(91)90717-yopenalex-snapshot
Epidemiology of colonic symptoms and the irritable bowel syndrome
inferredcites →https://doi.org/10.1016/0091-3057(95)00078-bopenalex-snapshot
The 5-HT4 receptor antagonist, GR113808, reduces ethanol intake in alcohol-preferring rats
inferredcites →https://doi.org/10.1016/0169-328x(91)90068-9openalex-snapshot
Benzamide derivatives provide evidence for the involvement of a 5-HT4 receptor type in the mechanism of action of serotonin in frog adrenocortical cells
inferredcites →https://doi.org/10.1016/0169-328x(94)90392-1openalex-snapshot
Identification and characterization of serotonin 5-HT4 receptor binding sites in human brain: comparison with other mammalian species
inferredcites →https://doi.org/10.1016/0223-5234(89)90004-4openalex-snapshot
Potential non-dopaminergic gastrointestinal prokinetic agents in the series of substituted benzamides
inferredcites →https://doi.org/10.1016/0223-5234(96)89139-2openalex-snapshot
Serotoninergic properties of new conformationally restricted benzamides
inferredcites →https://doi.org/10.1016/0960-894x(95)00115-aopenalex-snapshot
Synthesis and pharmacological activity of a macrocyclic benzamide
inferredcites →https://doi.org/10.1016/0968-0896(96)00037-5openalex-snapshot
Azabicyclic indole esters as potent 5-HT4 receptor antagonists
inferredcites →https://doi.org/10.1016/s0008-6363(98)00198-9openalex-snapshot
Effect of 5-HT4 receptor stimulation on the pacemaker current If in human isolated atrial myocytes
inferredcites →https://doi.org/10.1016/s0009-9236(97)90050-3openalex-snapshot
Clinical pharmacodynamics of SDZ HTF 919, a new 5-HT4 receptor agonist, in a model of slow colonic transit
inferredcites →https://doi.org/10.1016/s0014-2999(00)00858-xopenalex-snapshot
5-HT4 receptors do not mediate the antidepressant-like behavioral effects of fluoxetine in a modified forced swim test
inferredcites →https://doi.org/10.1016/s0014-2999(01)01087-1openalex-snapshot
The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound
inferredcites →https://doi.org/10.1016/s0014-2999(96)00474-8openalex-snapshot
The role of the 5-HT4 receptor in Cl− secretion in human jejunal mucosa
inferredcites →https://doi.org/10.1016/s0014-2999(96)00777-7openalex-snapshot
Characterization of the contractile response induced by 5-methoxytryptamine in rat stomach fundus strips
inferredcites →https://doi.org/10.1016/s0014-2999(96)00895-3openalex-snapshot
Characterisation of the 5-HT receptor potentiating neurotransmission in rabbit bladder
inferredcites →https://doi.org/10.1016/s0014-2999(98)00564-0openalex-snapshot
5-HT4 receptor antagonism does not affect motor and reward mechanisms in the rat
inferredcites →https://doi.org/10.1016/s0014-2999(99)00642-1openalex-snapshot
Localization of the 5-HT4 receptor in the human and the guinea pig colon
inferredcites →https://doi.org/10.1016/s0014-5793(97)00820-xopenalex-snapshot
Molecular and functional characterization of a 5‐HT4 receptor cloned from human atrium
inferredcites →https://doi.org/10.1016/s0016-5085(98)70203-3openalex-snapshot
5-Hydroxytryptamine4 receptor agonists initiate the peristaltic reflex in human, rat, and guinea pig intestine
inferredcites →https://doi.org/10.1016/s0021-5198(19)30767-xopenalex-snapshot
Effects of SK-951, a Benzofuran Derivative, as a Prokinetic Agent in Rats and Dogs
inferredcites →https://doi.org/10.1016/s0021-5198(19)31411-8openalex-snapshot
The Selective 5-Hydroxytryptamine (5-HT)4-Receptor Agonist RS67506 Enhances Lower Intestinal Propulsion in Mice
inferredcites →https://doi.org/10.1016/s0021-5198(19)34401-4openalex-snapshot
Cephaloridine(CER)-induced cytotoxicity in mouse S3 cellline stably expressing rat organic anion transporterl(rOATl).
inferredcites →https://doi.org/10.1016/s0021-5198(19)34863-2openalex-snapshot
Effects of Mg-deficiency on the responsiveness of the vascular smooth muscle strips from rat aorta
inferredcites →https://doi.org/10.1016/s0028-3908(00)00038-1openalex-snapshot
Differential modulation of the 5-HT4 receptor agonists and antagonist on rat learning and memory
inferredcites →https://doi.org/10.1016/s0028-3908(01)00085-5openalex-snapshot
RS 67333 and D-cycloserine accelerate learning acquisition in the rat
inferredcites →https://doi.org/10.1016/s0028-3908(01)00154-xopenalex-snapshot
Cloning and characterization of a novel human 5-HT4 receptor variant that lacks the alternatively spliced carboxy terminal exon. RT-PCR distribution in human brain and periphery of multiple 5-HT4 receptor variants
inferredcites →https://doi.org/10.1016/s0028-3908(96)00169-4openalex-snapshot
5-HT 4 Receptors Improve Social Olfactory Memory in the Rat
inferredcites →https://doi.org/10.1016/s0028-3908(97)00055-5openalex-snapshot
The Effects of Novel, Selective 5-Hydroxytryptamine (5-HT) 4 Receptor Ligands in Rat Spatial Navigation
inferredcites →https://doi.org/10.1016/s0091-3057(96)00224-9openalex-snapshot
Effects of 5-HT4 Receptor Agonists and Antagonists in Learning
inferredcites →https://doi.org/10.1016/s0140-6736(95)90595-2openalex-snapshot
Cisapride and torsades de pointes
inferredcites →https://doi.org/10.1016/s0169-328x(01)00095-xopenalex-snapshot
Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR
inferredcites →https://doi.org/10.1016/s0223-5234(00)00163-xopenalex-snapshot
Synthesis and preliminary pharmacological results on new naphthalene derivatives as 5-HT4 receptor ligands
inferredcites →https://doi.org/10.1016/s0223-5234(99)00158-0openalex-snapshot
Synthesis and pharmacological evaluation of carboxamide derivatives as selective serotoninergic 5-HT4 receptor agonists
inferredcites →https://doi.org/10.1016/s0248-8663(00)80020-xopenalex-snapshot
Perspectives physiopathologiques et thérapeutiques des nouveaux récepteurs sérotoninergiques: à propos du récepteur de type 4
inferredcites →https://doi.org/10.1016/s0300-483x(00)00314-0openalex-snapshot
Neurochemistry and neuropharmacology of emesis — the role of serotonin
inferredcites →https://doi.org/10.1016/s0300-9629(97)00085-6openalex-snapshot
Signal Transduction Pathways for Serotonin as an Intestinal Secretagogue
inferredcites →https://doi.org/10.1016/s0968-0896(99)00172-8openalex-snapshot
Benzimidazole derivatives. Part 1: Synthesis and structure–activity relationships of new benzimidazole-4-carboxamides and carboxylates as potent and selective 5-HT4 receptor antagonists
inferredcites →https://doi.org/10.1016/s0968-0896(99)00281-3openalex-snapshot
Benzamides derived from 1,2-diaminocyclopropane as novel ligands for human D2 and D3 dopamine receptors
inferredcites →https://doi.org/10.1021/jm00024a002openalex-snapshot
N-[(1-Butyl-4-piperidinyl)methyl]-3,4- dihydro-2H-[1,3]oxazino[3,2-a]indole- 10-carboxamide hydrochloride: the first potent and selective 5-HT4 receptor antagonist amide with oral activity.
inferredcites →https://doi.org/10.1021/jm00077a018openalex-snapshot
(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide
inferredcites →https://doi.org/10.1021/jm00086a019openalex-snapshot
SC-53116: the first selective agonist at the newly identified serotonin 5-HT4 receptor subtype
inferredcites →https://doi.org/10.1021/jm00086a020openalex-snapshot
Bis(maltolato)oxovanadium(IV) is a potent insulin mimic
inferredcites →https://doi.org/10.1021/jm0009538openalex-snapshot
New Arylpiperazine Derivatives as Antagonists of the Human Cloned 5-HT4Receptor Isoforms
inferredcites →https://doi.org/10.1021/jm00106a023openalex-snapshot
Novel benzamides as selective and potent gastrokinetic agents. 2. Synthesis and structure-activity relationships of 4-amino-5-chloro-2-ethoxy-N-[[4-(4-fluorobenzyl)-2-morpholinyl]methyl]benzamide citrate (AS-4370) and related compounds
inferredcites →https://doi.org/10.1021/jm00106a024openalex-snapshot
Structure-activity relationship of quinazolinedione inhibitors of calcium-independent phosphodiesterase
inferredcites →https://doi.org/10.1021/jm00117a009openalex-snapshot
Etodolac, a novel antiinflammatory agent. The syntheses and biological evaluation of its metabolites
inferredcites →https://doi.org/10.1021/jm00150a015openalex-snapshot
Substituted benzamides with conformationally restricted side chains. 1. Quinolizidine derivatives as selective gastric prokinetic agents
inferredcites →https://doi.org/10.1021/jm00168a011openalex-snapshot
Conformation-activity relationship study of 5-HT3 receptor antagonists and a definition of a model for this receptor site
inferredcites →https://doi.org/10.1021/jm00168a012openalex-snapshot
Angiotensin converting enzyme inhibitors. 9. Novel [[N-(1-carboxyl-3-phenylpropyl)amino]acyl]glycine derivatives with diuretic activity
inferredcites →https://doi.org/10.1021/jm00170a009openalex-snapshot
Synthesis of a new class of 2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid derivatives as highly potent 5-HT3 receptor antagonists
inferredcites →https://doi.org/10.1021/jm00170a010openalex-snapshot
Synthesis and biological evaluation of new antimuscarinic compounds with amidine basic centers. A useful bioisosteric replacement of classical cationic heads
inferredcites →https://doi.org/10.1021/jm960320mopenalex-snapshot
New Esters of 4-Amino-5-chloro-2-methoxybenzoic Acid as Potent Agonists and Antagonists for 5-HT4Receptors
inferredcites →https://doi.org/10.1021/jm960853vopenalex-snapshot
Arylcarbamate Derivatives of 1-Piperidineethanol as Potent Ligands for 5-HT4Receptors
inferredcites →https://doi.org/10.1021/jm970857fopenalex-snapshot
Synthesis and Structure−Activity Relationships of Potent and Orally Active 5-HT4 Receptor Antagonists: Indazole and Benzimidazolone Derivatives
inferredcites →https://doi.org/10.1021/jm981098jopenalex-snapshot
2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with Selective Affinity for the 5-HT4Receptor: Synthesis and Structure−Affinity and Structure−Activity Relationships of a New Series of Partial Agonist and Antagonist Derivatives
inferredcites →https://doi.org/10.1023/a:1007908707650openalex-snapshot
Comparative receptor mapping of serotoninergic 5-HT3 and 5-HT4 binding sites*
inferredcites →https://doi.org/10.1038/sj.bjp.0701513openalex-snapshot
The influence of 5‐HT2and 5‐HT4receptor antagonists to modify drug induced disinhibitory effects in the mouse light/dark test
inferredcites →https://doi.org/10.1038/sj.bjp.0702163openalex-snapshot
The 5‐HT4 receptor antagonist ML10375 inhibits the constitutive activity of human 5‐HT4(c) receptor
inferredcites →https://doi.org/10.1038/sj.bjp.0702665openalex-snapshot
Pharmacological characterization of 5‐HT4 receptors mediating relaxation of canine isolated rectum circular smooth muscle
inferredcites →https://doi.org/10.1038/sj.bjp.0702762openalex-snapshot
Evidence for 5‐HT7 receptors mediating relaxation of human colonic circular smooth muscle
inferredcites →https://doi.org/10.1038/sj.bjp.0703101openalex-snapshot
Isolation of the serotoninergic 5‐HT4(e) receptor from human heart and comparative analysis of its pharmacological profile in C6‐glial and CHO cell lines
inferredcites →https://doi.org/10.1038/sj.bjp.0703254openalex-snapshot
An improved in vitro bioassay for the study of 5‐HT4 receptors in the human isolated large intestinal circular muscle
inferredcites →https://doi.org/10.1038/sj.bjp.0703356openalex-snapshot
Exploration of the ligand binding site of the human 5‐HT4 receptor by site‐directed mutagenesis and molecular modeling
inferredcites →https://doi.org/10.1038/sj.bjp.0703367openalex-snapshot
Increased defecation during stress or after 5‐hydroxytryptophan: selective inhibition by the 5‐HT4 receptor antagonist, SB‐207266
inferredcites →https://doi.org/10.1038/sj.bjp.0703615openalex-snapshot
5‐HT4 receptors on cholinergic nerves involved in contractility of canine and human large intestine longitudinal muscle
inferredcites →https://doi.org/10.1038/sj.bjp.0703641openalex-snapshot
Pharmacological characterization of the human 5‐HT4(d) receptor splice variant stably expressed in Chinese hamster ovary cells
inferredcites →https://doi.org/10.1042/0264-6021:3530627openalex-snapshot
5-Hydroxytryptamine 4(a) receptor expressed in Sf9 cells is palmitoylated in an agonist-dependent manner
inferredcites →https://doi.org/10.1046/j.1365-2036.1999.00625.xopenalex-snapshot
5‐HT4 receptor antagonism in irritable bowel syndrome: effect of SB‐207266‐A on rectal sensitivity and small bowel transit
inferredcites →https://doi.org/10.1046/j.1365-2036.2001.00925.xopenalex-snapshot
Tegaserod
inferredcites →https://doi.org/10.1046/j.1464-410x.2001.02038.xopenalex-snapshot
Effect of different 5‐hydroxytryptamine receptor subtype antagonists on the micturition reflex in rats
inferredcites →https://doi.org/10.1046/j.1471-4159.1997.69051810.xopenalex-snapshot
Cloning and Expression of a Human Serotonin 5‐HT4 Receptor cDNA
inferredcites →https://doi.org/10.1046/j.1471-4159.1998.70062252.xopenalex-snapshot
Cloning, Expression, and Pharmacology of Four Human 5‐Hydroxytryptamine4 Receptor Isoforms Produced by Alternative Splicing in the Carboxyl Terminus
inferredcites →https://doi.org/10.1046/j.1471-4159.2000.740478.xopenalex-snapshot
Structure of the Human Serotonin 5‐HT4 Receptor Gene and Cloning of a Novel 5‐HT4 Splice Variant
inferredcites →https://doi.org/10.1053/gast.2001.21166openalex-snapshot
Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder
inferredcites →https://doi.org/10.1093/embo-reports/kve003openalex-snapshot
Constitutively active mutants of 5‐HT4 receptors are they in unique active states?
inferredcites →https://doi.org/10.1097/00001756-199309000-00007openalex-snapshot
[3H]-GR113808 labels 5-HT4 receptors in the human and guinea-pig brain
inferredcites →https://doi.org/10.1097/00001756-199406020-00018openalex-snapshot
5-HT4 receptor stimulation facilitates acetylcholine release in rat frontal cortex
inferredcites →https://doi.org/10.1097/00001756-199902250-00019openalex-snapshot
5-HT4 receptor modulation of acetylcholine outflow in guinea pig brain slices
inferredcites →https://doi.org/10.1111/j.1476-5381.1990.tb14108.xopenalex-snapshot
A 5‐hydroxytryptamine receptor in human atrium
inferredcites →https://doi.org/10.1111/j.1476-5381.1990.tb14113.xopenalex-snapshot
Characterization of 5‐HT3 and ‘atypical’ 5‐HT receptors mediating guinea‐pig ileal contractions in vitro
inferredcites →https://doi.org/10.1111/j.1476-5381.1991.tb12140.xopenalex-snapshot
Further characterization, by use of tryptamine and benzamide derivatives, of the putative 5‐HT4 receptor mediating tachycardia in the pig
inferredcites →https://doi.org/10.1111/j.1476-5381.1991.tb12211.xopenalex-snapshot
Peristalsis evoked by 5‐HT and renzapride: evidence for putative 5‐HT 4 receptor activation
inferredcites →https://doi.org/10.1111/j.1476-5381.1992.tb12788.xopenalex-snapshot
5‐Hydroxytryptamine (5‐HT) mediates potent relaxation in the sheep isolated pulmonary vein via activation of 5‐HT4 receptors
inferredcites →https://doi.org/10.1111/j.1476-5381.1993.tb12812.xopenalex-snapshot
The action of SDZ 205,557 at 5‐hydroxytryptamine (5‐HT3 and 5‐HT4) receptors
inferredcites →https://doi.org/10.1111/j.1476-5381.1993.tb13617.xopenalex-snapshot
Development of a radioligand binding assay for 5‐HT4 receptors in guinea‐pig and rat brain
inferredcites →https://doi.org/10.1111/j.1476-5381.1993.tb13780.xopenalex-snapshot
RS 23597‐190: a potent and selective 5‐HT4receptor antagonist
inferredcites →https://doi.org/10.1111/j.1476-5381.1993.tb13915.xopenalex-snapshot
Antagonism of the stimulatory effects of efaroxan and glibenclamide in rat pancreatic islets by the imidazoline, RX801080
inferredcites →https://doi.org/10.1111/j.1476-5381.1993.tb13916.xopenalex-snapshot
Characterization of the 5‐HT4 receptor mediating tachycardia in piglet isolated right atrium
inferredcites →https://doi.org/10.1111/j.1476-5381.1993.tb14003.xopenalex-snapshot
5‐HT 4 receptor mediated facilitation of the emptying phase of the peristaltic reflex in the guinea‐pig isolated ileum
inferredcites →https://doi.org/10.1111/j.1476-5381.1993.tb14006.xopenalex-snapshot
The guinea‐pig distal colon ‐ a sensitive preparation for the investigation of 5‐HT4receptor‐mediated contractions
inferredcites →https://doi.org/10.1111/j.1476-5381.1994.tb13048.xopenalex-snapshot
Differences in the effects of NK1‐receptor antagonists, (±)‐CP 96,345 and CP 99,994, on agonist‐induced responses in guinea‐pig trachea
inferredcites →https://doi.org/10.1111/j.1476-5381.1994.tb13148.xopenalex-snapshot
The effects of SB 204070, a highly potent and selective 5‐HT4receptor antagonist, on guinea‐pig distal colon
inferredcites →https://doi.org/10.1111/j.1476-5381.1994.tb14046.xopenalex-snapshot
Evidence for an inhibitory 5‐HT4 receptor in urinary bladder of Rhesus and Cynomolgus monkeys
inferredcites →https://doi.org/10.1111/j.1476-5381.1994.tb16163.xopenalex-snapshot
Characterization of the 5‐HT receptor potentiating neuromuscular cholinergic transmission in strips of human isolated detrusor muscle
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5‐Hydroxytryptamine (5‐HT)4 receptors in post mortem human brain tissue: distribution, pharmacology and effects of neurodegenerative diseases
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Electrophysiological and Antiarrhythmic Effects of the Atrial Selective 5-HT 4 Receptor Antagonist RS-100302 in Experimental Atrial Flutter and Fibrillation
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Sensitization of Human Atrial 5-HT4Receptors by Chronic β-Blocker Treatment
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METOCLOPRAMIDE INCREASES PLASMA ALDOSTERGNE CONCENTRATION IN MAN
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Effect of prolonged administration of the serotonin4 (5-HT4) receptor agonist cisapride on aldosterone secretion in healthy volunteers

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Prokinetic drugs that stimulate 5-HT4-serotonin receptors in the human atrium
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Two transmembrane Cys residues are involved in 5-HT4 receptor dimerization
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Quantitative mRNA analysis of serotonin 5-HT4 receptor isoforms, calcium handling proteins and ion channels in human atrial fibrillation
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Bridgehead-methyl analog of SC-53116 as a 5-HT4 agonist
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Azaadamantane benzamide 5-HT4 agonists: gastrointestinal prokinetic SC-54750
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Identification of a 5-HT4 receptor antagonist clinical candidate through side-chain modification
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Cognitive effects of SL65.0155, a serotonin 5-HT4 receptor partial agonist, in animal models of amnesia
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Simultaneous tritium labelling of two potent 5-HT4 ligands
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Synthesis and characterization of a iodine-125-labeled pyrrolo[1,2-a]thieno[3,2-e]pyrazine and evaluation as a potential 5-HT4R SPECT tracer
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Synthesis and pharmacological properties of a new hydrophilic and orally bioavailable 5-HT4 antagonist
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Synthesis and structure–activity relationship studies in serotonin 5-HT4 receptor ligands based on a benzo[de][2,6]naphthridine scaffold
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Synthesis and SAR of Imidazo[1,5-a]pyridine derivatives as 5-HT4 receptor partial agonists for the treatment of cognitive disorders associated with Alzheimer's disease
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5-HT4 receptor and Alzheimer's disease: The amyloid connection
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Regulation of the amyloid precursor protein ectodomain shedding by the 5‐HT4 receptor and Epac
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Constitutive dimerization of human serotonin 5‐HT4 receptors in living cells
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Modulation of memory processes and cellular excitability in the dentate gyrus of freely moving rats by a 5-HT4 receptors partial agonist, and an antagonist
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Visceral analgesic effect of 5-HT4 receptor agonist in rats involves the rostroventral medulla (RVM)
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Modulation of hippocampal excitability by 5-HT4 receptor agonists persists in a transgenic model of Alzheimer's disease
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5-Hydroxytryptamine receptors in the human cardiovascular system
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The role of 5-HT4 serotonin receptors in the CA1 hippocampal region on memory acquisition impairment induced by total (TSD) and REM sleep deprivation (RSD)
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A two-step synthesis of aminopropylpiperidines via aminopropargylpyridines, suitable for the synthesis of a new class of 5-HT4 ligands
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Large-scale molecular dynamics of a G protein-coupled receptor, the human 5-HT4 serotonin receptor, in a lipid bilayer
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Voltage gated ion channels blockade is the underlying mechanism of BIMU8 induced cardiotoxicity
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Differential functional effects of two 5-HT receptor isoforms in adult cardiomyocytes
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The Literature of Heterocyclic Chemistry, Part IX, 2002–2004
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Chemoenzymatic Approaches to Izidine Alkaloids: An Efficient Total Synthesis of (+)-Absouline and Laburnamine
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Higher-End Serotonin Receptors: 5-HT5, 5-HT6, and 5-HT7
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Synthesis and Characterization of the First Fluorescent Antagonists for Human 5-HT4Receptors
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Design and Synthesis of Specific Probes for Human 5-HT4 Receptor Dimerization Studies
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Pyrrolizidine Esters and Amides as 5-HT4 Receptor Agonists and Antagonists
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Synthesis of Specific Bivalent Probes That Functionally Interact with 5-HT4 Receptor Dimers
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Novel Quinolizidinyl Derivatives as Antiarrhythmic Agents: 2. Further Investigation
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Synthesis, Structure−Affinity Relationships, and Radiolabeling of Selective High-Affinity 5-HT4Receptor Ligands as Prospective Imaging Probes for Positron Emission Tomography
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Discovery and Pharmacological Profile of New 1H-Indazole-3-carboxamide and 2H-Pyrrolo[3,4-c]quinoline Derivatives as Selective Serotonin 4 Receptor Ligands
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Identification of Multiple 5-HT4Partial Agonist Clinical Candidates for the Treatment of Alzheimer’s Disease
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Design, Synthesis, and Biological Evaluation of New 5-HT4 Receptor Agonists: Application as Amyloid Cascade Modulators and Potential Therapeutic Utility in Alzheimer’s Disease
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aza-Prins-pinacol Approach to 7-Azabicyclo[2.2.1]heptanes and Ring Expansion to [3.2.1]Tropanes
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New insights into the human 5‐HT4 receptor binding site: exploration of a hydrophobic pocket
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Porcine left atrial and sinoatrial 5‐HT4receptor‐induced responses: fading of the response and influence of development
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Differences between the abilities of tegaserod and motilin receptor agonists to stimulate gastric motilityin vitro
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5‐HT4 receptor agonists increase sAPPα levels in the cortex and hippocampus of male C57BL/6j mice
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Identification and functional characterisation of 5-HT4 receptor in sea cucumber Apostichopus japonicus (Selenka)
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Multivalent ligands for the serotonin 5-HT 4 receptor
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A versatile access to vicinal diamine motifs by highly anti-selective asymmetric vinylogous Mannich reactions: an efficient total synthesis of (+)-absouline
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Development of subnanomolar-affinity serotonin 5-HT 4 receptor ligands based on quinoline structures
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Functional studies of the 5′-untranslated region of human 5-HT4 receptor mRNA
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Synthesis of Quinoline Derivatives as 5-HT4 Receptor Ligands
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Surface receptor-targeted protein-based nanocarriers for drug delivery: advances in cancer therapy
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Drug toxicity on cardiac pacemaking: A multi-scale modelling study
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Systematic review: cardiovascular safety profile of 5‐ HT 4 agonists developed for gastrointestinal disorders
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Pharmacodynamic effects of a novel prokinetic 5‐HT 4 receptor agonist, ATI‐7505, in humans
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5‐HT 4 receptor agonists: similar but not the same
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Distribution of serotonin receptors and interacting proteins in the human sigmoid colon
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Selective desensitization of the 5‐HT4receptor‐mediated response in pig atrium but not in stomach
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Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors
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Cardiovascular safety of prokinetic agents: A focus on drug‐induced arrhythmias
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Luminal 5‐HT4 receptors—A successful target for prokinetic actions
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Electrophysiological Effects of Prucalopride, a Novel Enterokinetic Agent, on Isolated Atrial Myocytes from Patients Treated with β-Adrenoceptor Antagonists
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Differential Effects of 5-Hydroxytryptamine4 Receptor Agonists at Gastric versus Cardiac Receptors: An Operational Framework to Explain and Quantify Organ-Specific Behavior
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International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
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Expression and function of 5-HT 4 receptors in the mouse enteric nervous system
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Desensitization of the peristaltic reflex induced by mucosal stimulation with the selective 5-HT4agonist tegaserod
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Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes
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Alternative splicing and exon duplication generates 10 unique porcine 5-HT4 receptor splice variants including a functional homofusion variant
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Electroacupuncture at ST25 Inhibits Cisapride‐Induced Gastric Motility in an Intensity‐Dependent Manner
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Investigations into the Binding Affinities of Different Human 5-HT4 Receptor Splice Variants
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Immunomodulation by maternal autoantibodies of the fetal serotoninergic 5-HT4receptor and its consequences in early BALB/c mouse embryonic development
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Effects of Tegaserod on Ileal Peristalsis of Guinea Pig In Vitro
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Serotonin as a Regulator of the Hypothalamic-Pituitary-Interrenal Axis in Rainbow Trout (Oncorhynchus mykiss)
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Tegaserod for the Treatment of Irritable Bowel Syndrome
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A Review on Pathophysiological Aspects of Sleep Deprivation
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Expression and Impact of Adenosine A3 Receptors on Calcium Homeostasis in Human Right Atrium
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Cardiac Roles of Serotonin (5-HT) and 5-HT-Receptors in Health and Disease
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5-HT4 Receptor Agonists for the Treatment of Alzheimer’s Dsease
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Production and Function of Serotonin in Cardiac Cells
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Serotonin and the CNS - New Developments in Pharmacology and Therapeutics
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Small Molecule Drugs for Treatment of Alzheimer’s Diseases Developed on the Basis of Mechanistic Understanding of the Serotonin Receptors 4 and 6
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Implication du récepteur sérotoninergique 5-HT4 dans la modulation de la perméabilité de la barrière hémato-encéphalique
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EFFECTS OF SEROTONIN AGONISTS AND DOXAPRAM ON RESPIRATORY DEPRESSION AND HYPOXEMIA IN ETORPHINE-IMMOBILIZED IMPALA (AEPYCEROS MELAMPUS)
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