On the public citation graph
Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens: Synthesis, in Vitro Biological Activity, Pharmacokinetics, and Antitumor Activity in the LAPC4 Human Prostate Cancer Xenograft Model
0 signed · 265 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/archsurg.1941.01210140043004openalex-snapshot
STUDIES ON PROSTATIC CANCER
inferredcites →https://doi.org/10.1002/pros.2990250707openalex-snapshot
Role of maximal androgen blockade in advanced prostate cancer
inferredcites →https://doi.org/10.1006/abio.1998.2993openalex-snapshot
Cytochrome P450c17-ExpressingEscherichia colias a First-Step Screening System for 17α-Hydroxylase- C17,20-lyase Inhibitors
inferredcites →https://doi.org/10.1016/j.jsbmb.2004.07.006openalex-snapshot
Potent CYP17 inhibitors: improved syntheses, pharmacokinetics and anti-tumor activity in the LNCaP human prostate cancer model
inferredcites →https://doi.org/10.1016/s0022-5347(01)64924-3openalex-snapshot
Ketoconazole Retains Activity in Advanced Prostate Cancer Patients with Progression Despite Flutamide Withdrawal
inferredcites →https://doi.org/10.1016/s0022-5347(17)37466-9openalex-snapshot
Prevention of Urinary Tract Infection and Bacteremia Following Transurethral Surgery: Oral Lomefloxacin Compared to Parenteral Cefotaxime
inferredcites →https://doi.org/10.1016/s0022-5347(17)40639-2openalex-snapshot
Ketoconazole: A Possible Direct Cytotoxic Effect on Prostate Carcinoma Cells
inferredcites →https://doi.org/10.1016/s0022-5347(17)51007-1openalex-snapshot
Ketoconazole: A Novel and Rapid Treatment for Advanced Prostatic Cancer
inferredcites →https://doi.org/10.1016/s0076-6879(78)52030-2openalex-snapshot
[28] Analysis of polycyclic aromatic hydrocarbons and their metabolites by high-pressure liquid chromatography
inferredcites →https://doi.org/10.1016/s0094-0143(21)01388-4openalex-snapshot
Physiologic Basis of Endocrine Therapy for Prostatic Cancer
inferredcites →https://doi.org/10.1016/s0960-0760(03)00070-0openalex-snapshot
Effects of novel 17α-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo
inferredcites →https://doi.org/10.1021/jm0208471openalex-snapshot
Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-N-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors
inferredcites →https://doi.org/10.1021/jo00123a028openalex-snapshot
Total synthesis of grossularines-1 and -2
inferredcites →https://doi.org/10.1038/nrc801openalex-snapshot
A history of prostate cancer treatment
inferredcites →https://doi.org/10.1038/sj.bjc.6690739openalex-snapshot
Effects of new 17α-hydroxylase/C17,20-lyase inhibitors on LNCaP prostate cancer cell growth in vitro and in vivo
inferredcites →https://doi.org/10.1080/00304949709355175openalex-snapshot
A CONVENIENT, LARGE-SCALE SYNTHESIS OF ABIRATERONE ACETATE [3β-ACETOXY-17-(3-PYRIDYL)ANDROSTA-5,16-DIENE], A POTENTIAL NEW DRUG FOR THE TREATMENT OF PROSTATE CANCER
inferredcites →https://doi.org/10.1158/0008-5472.can-04-1752openalex-snapshot
Symposium on Androgen Action in Prostate Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-1146-03openalex-snapshot
The Androgen Axis in Recurrent Prostate Cancer
inferredcites →https://doi.org/10.1177/216507996801601208openalex-snapshot
1969 Cancer Facts and Figures
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4825103openalex-extracted
Steroidal 21-Imidazolium Salt Derivatives: Synthesis and Antitumoral Activity
inferred← citeshttps://doi.org/10.1002/047084289x.rc021.pub3openalex-snapshot
Carbonyl(chloro)bis(triphenylphosphine)rhodium(I)
inferred← citeshttps://doi.org/10.1002/9781119774198.ch2openalex-snapshot
Stability of Steroid Hormone Receptors
inferred← citeshttps://doi.org/10.1002/ange.201407219openalex-snapshot
Shifting Chemical Equilibria in Flow—Efficient Decarbonylation Driven by Annular Flow Regimes
inferred← citeshttps://doi.org/10.1002/anie.201407219openalex-snapshot
Shifting Chemical Equilibria in Flow—Efficient Decarbonylation Driven by Annular Flow Regimes
inferred← citeshttps://doi.org/10.1002/ardp.201100361openalex-snapshot
Synthesis and Antioxidant Activity of a New Class of Bis and Tris Heterocycles
inferred← citeshttps://doi.org/10.1002/ardp.201400255openalex-snapshot
New CYP17 Hydroxylase Inhibitors: Synthesis, Biological Evaluation, QSAR, and Molecular Docking Study of New Pregnenolone Analogs
inferred← citeshttps://doi.org/10.1002/cjoc.200890312openalex-snapshot
Synthesis and Antibacterial Activity of Some New 2,5‐Disubstituted‐1,3,4‐oxadiazole Derivatives
inferred← citeshttps://doi.org/10.1002/cmdc.201000065openalex-snapshot
The Role of Fluorine Substitution in Biphenyl Methylene Imidazole‐Type CYP17 Inhibitors for the Treatment of Prostate Carcinoma
inferred← citeshttps://doi.org/10.1002/ejoc.201300719openalex-snapshot
An Efficient Approach to Azolyl‐Substituted Steroids through Copper‐Catalyzed Ullmann C–N Coupling
inferred← citeshttps://doi.org/10.1002/jhet.3070openalex-snapshot
Synthesis of Heterocyclic‐Substituted Novel Hydroxysteroids with Regioselective and Stereoselective Reactions
inferred← citeshttps://doi.org/10.1002/jhet.3916openalex-snapshot
Synthesis of amide‐linked benzazolyl isoxazoles adopting green methods and evaluation as antimicrobials
inferred← citeshttps://doi.org/10.1002/jlcr.3516openalex-snapshot
Effect of N‐methyl deuteration on pharmacokinetics and pharmacodynamics of enzalutamide
inferred← citeshttps://doi.org/10.1002/pros.20656openalex-snapshot
17α‐estradiol inhibits LAPC‐4 prostatic tumor cell proliferation in cell cultures and tumor growth in xenograft animals
inferred← citeshttps://doi.org/10.1002/slct.202202286openalex-snapshot
L‐Proline Catalyzed Synthesis of Steroidal Pyridones And Their DFT Studies
inferred← citeshttps://doi.org/10.1002/slct.202203393openalex-snapshot
Design and Synthesis of New Agents for Prostate Cancer Treatment Inspired by Steroidal CYP17 A1 Inhibitors
inferred← citeshttps://doi.org/10.1007/7081_2012_95openalex-snapshot
Metalation of Pyrazine and Quinoxaline
inferred← citeshttps://doi.org/10.1007/978-1-4471-2864-9_74openalex-snapshot
Hormone-Based Therapies for Castration-Resistant Prostate Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4939-1176-9_6openalex-snapshot
The Androgen Receptor as a Therapeutic Target for Castration-Resistant Prostate Cancer
inferred← citeshttps://doi.org/10.1007/978-3-319-04385-2_10openalex-snapshot
New Medical Strategies: The Role of Oncologist in an MDT
inferred← citeshttps://doi.org/10.1007/978-3-319-12108-6_12openalex-snapshot
P450 Enzymes in Steroid Processing
inferred← citeshttps://doi.org/10.1007/978-3-319-16009-2_9openalex-snapshot
Cytochrome P450 Enzymes and Electrochemistry: Crosstalk with Electrodes as Redox Partners and Electron Sources
inferred← citeshttps://doi.org/10.1007/978-94-007-2558-4_12openalex-snapshot
Androgen Receptor Regulation of Prostate Cancer Progression and Metastasis
inferred← citeshttps://doi.org/10.1007/s00044-013-0636-yopenalex-snapshot
Synthesis, evaluation and docking studies on steroidal pyrazolones as anticancer and antimicrobial agents
inferred← citeshttps://doi.org/10.1007/s00044-013-0668-3openalex-snapshot
Modification of carboxylated multiwall nanotubes with benzotriazole derivatives and study of their anticancer activities
inferred← citeshttps://doi.org/10.1007/s00044-013-0884-xopenalex-snapshot
Synthesis and antioxidant activity of amido-linked benzoxazolyl/benzothiazolyl/benzimidazolyl-pyrroles and pyrazoles
inferred← citeshttps://doi.org/10.1007/s00044-015-1480-zopenalex-snapshot
Synthesis and CYP17α hydroxylase inhibition activity of new 3α- and 3β-ester derivatives of pregnenolone and related ether analogues
inferred← citeshttps://doi.org/10.1007/s00210-019-01622-5openalex-snapshot
Abiraterone acetate exerts a cytotoxic effect in human prostate cancer cell lines
inferred← citeshttps://doi.org/10.1007/s10555-013-9472-2openalex-snapshot
Novel drugs targeting the androgen receptor pathway in prostate cancer
inferred← citeshttps://doi.org/10.1007/s10555-013-9474-0openalex-snapshot
Androgen receptor signaling in prostate cancer
inferred← citeshttps://doi.org/10.1007/s10593-013-1158-8openalex-snapshot
Synthesis of steroids with nitrogen-containing substituents in ring D (Review)
inferred← citeshttps://doi.org/10.1007/s11030-020-10038-wopenalex-snapshot
A novel pregnene analogs: synthesis, cytotoxicity on prostate cancer of PC-3 and LNCPa-AI cells and in silico molecular docking study
inferred← citeshttps://doi.org/10.1007/s11094-016-1459-1openalex-snapshot
Four-Step Synthesis of Abiraterone Acetate from Dehydroepiandrosterone
inferred← citeshttps://doi.org/10.1007/s12039-010-0094-8openalex-snapshot
Facile synthesis of novel benzotriazole derivatives and their antibacterial activities
inferred← citeshttps://doi.org/10.1007/s12672-016-0259-0openalex-snapshot
The Metabolism, Analysis, and Targeting of Steroid Hormones in Breast and Prostate Cancer
inferred← citeshttps://doi.org/10.1007/s40203-026-00626-3openalex-snapshot
Integrated in silico investigation of an androstendiol derivative (monoxetanol) as a potential anti-prostate cancer agent: insights from molecular docking, MD simulations, MM/PBSA, ADMET, and DFT analyses
inferred← citeshttps://doi.org/10.1016/b978-0-12-396521-9.00011-5openalex-snapshot
The Renaissance of CYP17 Inhibitors for the Treatment of Prostate Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.12396-0openalex-snapshot
Targeting the Androgen Receptor Signaling Axis
inferred← citeshttps://doi.org/10.1016/b978-0-12-800077-9.00057-8openalex-snapshot
Second-Line Hormonal for Castrate-Resistant Prostate Cancer
inferred← citeshttps://doi.org/10.1016/b978-0-12-817825-6.00011-2openalex-snapshot
Ring transformations by heterogeneous catalysis
inferred← citeshttps://doi.org/10.1016/j.ajur.2018.07.003openalex-snapshot
Current strategies for targeting the activity of androgen receptor variants
inferred← citeshttps://doi.org/10.1016/j.apsb.2022.09.010openalex-snapshot
Benzimidazole and its derivatives as cancer therapeutics: The potential role from traditional to precision medicine
inferred← citeshttps://doi.org/10.1016/j.bcp.2011.08.020openalex-snapshot
A novel steroidal antiandrogen targeting wild type and mutant androgen receptors
inferred← citeshttps://doi.org/10.1016/j.beem.2008.01.003openalex-snapshot
Intracrine androgen metabolism in prostate cancer progression: mechanisms of castration resistance and therapeutic implications
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103142openalex-snapshot
Novel steroidal 1,3,4-thiadiazines: Synthesis and biological evaluation in androgen receptor-positive prostate cancer 22Rv1 cells
inferred← citeshttps://doi.org/10.1016/j.bioorg.2023.106700openalex-snapshot
Salinization Dramatically Enhance the Anti-Prostate Cancer Efficacies of AR/AR-V7 and Mnk1/2 Molecular Glue Degraders, Galeterone and VNPP433-3β Which Outperform Docetaxel and Enzalutamide in CRPC CWR22Rv1 Xenograft Mouse Model
inferred← citeshttps://doi.org/10.1016/j.bmc.2006.01.033openalex-snapshot
Synthesis, anticonvulsant, and anti-inflammatory evaluation of some new benzotriazole and benzofuran-based heterocycles
inferred← citeshttps://doi.org/10.1016/j.bmc.2007.03.019openalex-snapshot
First pharmacophore-based identification of androgen receptor down-regulating agents: Discovery of potent anti-prostate cancer agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2007.05.046openalex-snapshot
Targeting cytochrome P450 enzymes: A new approach in anti-cancer drug development
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.02.031openalex-snapshot
Potent anti-prostate cancer agents derived from a novel androgen receptor down-regulating agent
inferred← citeshttps://doi.org/10.1016/j.bmc.2010.08.029openalex-snapshot
20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growth
inferred← citeshttps://doi.org/10.1016/j.bmc.2010.10.049openalex-snapshot
Discovery of 1H-benzo[d][1,2,3]triazol-1-yl 3,4,5-trimethoxybenzoate as a potential antiproliferative agent by inhibiting histone deacetylase
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.04.043openalex-snapshot
Synthesis, biological evaluation, and molecular docking studies of novel 1,3,4-oxadiazole derivatives possessing benzotriazole moiety as FAK inhibitors with anticancer activity
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.09.063openalex-snapshot
17(E)-Picolinylidene androstane derivatives as potential inhibitors of prostate cancer cell growth: Antiproliferative activity and molecular docking studies
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.12.071openalex-snapshot
Synthesis of new conjugated coumarin–benzimidazole hybrids and their anticancer activity
inferred← citeshttps://doi.org/10.1016/j.bmcl.2021.128448openalex-snapshot
Design, synthesis, and biological evaluation of phenyl thiazole-based AR-V7 degraders
inferred← citeshttps://doi.org/10.1016/j.bmcl.2025.130515openalex-snapshot
Design and synthesis of Tetrahydroindeno[4,5-c]chromen-4(3H)-one derivatives as antiproliferative agents for prostate Cancer cells
inferred← citeshttps://doi.org/10.1016/j.bulcan.2015.04.016openalex-snapshot
Les nouvelles thérapies dans le cancer de la prostate métastatique
inferred← citeshttps://doi.org/10.1016/j.canlet.2017.03.022openalex-snapshot
Targeting androgen receptor versus targeting androgens to suppress castration resistant prostate cancer
inferred← citeshttps://doi.org/10.1016/j.coph.2008.06.004openalex-snapshot
Targeting CYP17: established and novel approaches in prostate cancer
inferred← citeshttps://doi.org/10.1016/j.csbj.2015.10.001openalex-snapshot
Comparisons of Prostate Cancer Inhibitors Abiraterone and TOK-001 Binding with CYP17A1 through Molecular Dynamics
inferred← citeshttps://doi.org/10.1016/j.ddstr.2011.02.004openalex-snapshot
Novel androgen deprivation therapy (ADT) in the treatment of advanced prostate cancer
inferred← citeshttps://doi.org/10.1016/j.ecl.2011.05.013openalex-snapshot
New Hormonal Therapies for Castration-Resistant Prostate Cancer
inferred← citeshttps://doi.org/10.1016/j.ejmech.2011.05.030openalex-snapshot
Synthesis, characterization and biological evaluation of some 16β-azolyl-3β-amino-5α-androstane derivatives as potential anticancer agents
inferred← citeshttps://doi.org/10.1016/j.ejmech.2011.05.032openalex-snapshot
Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain
inferred← citeshttps://doi.org/10.1016/j.ejmech.2013.02.008openalex-snapshot
Coumarins hinged directly on benzimidazoles and their ribofuranosides to inhibit hepatitis C virus
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113420openalex-snapshot
Progress in developing MNK inhibitors
inferred← citeshttps://doi.org/10.1016/j.ejmech.2026.119300openalex-snapshot
Synthesis and biological activity of steroid conjugates of five-membered N-heterocycles with one or two nitrogen atoms: A review covering the years 2020-2025
inferred← citeshttps://doi.org/10.1016/j.ejphar.2008.01.041openalex-snapshot
A novel benzotriazole derivative inhibits proliferation of human hepatocarcinoma cells by increasing oxidative stress concomitant mitochondrial damage
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2018.05.010openalex-snapshot
Interaction of 17α-hydroxylase, 17(20)-lyase (CYP17A1) inhibitors – abiraterone and galeterone – with human sterol 14α-demethylase (CYP51A1)
inferred← citeshttps://doi.org/10.1016/j.jorganchem.2012.08.013openalex-snapshot
Synthesis of ferrocene-labelled steroid derivatives via homogeneous catalytic methods
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2009.03.011openalex-snapshot
Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2010.11.005openalex-snapshot
CYP17 inhibitors for prostate cancer therapy
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2013.04.006openalex-snapshot
Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2016.04.021openalex-snapshot
The hunt for a selective 17,20 lyase inhibitor; learning lessons from nature
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2023.106280openalex-snapshot
Oxazolinyl derivatives of androst-16-ene as inhibitors of CYP17A1 activity and prostate carcinoma cells proliferation: Effects of substituents in oxazolinyl moiety
inferred← citeshttps://doi.org/10.1016/j.mce.2010.09.013openalex-snapshot
The natural compounds atraric acid and N-butylbenzene-sulfonamide as antagonists of the human androgen receptor and inhibitors of prostate cancer cell growth
inferred← citeshttps://doi.org/10.1016/j.mce.2021.111261openalex-snapshot
Steroidogenic cytochrome P450 17A1 structure and function
inferred← citeshttps://doi.org/10.1016/j.molstruc.2022.132577openalex-snapshot
Synthesis, structural, computational, and antiproliferative activity studies of new steroidal tetrazole derivatives
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2005.07.006openalex-snapshot
CYP17- and CYP11B-dependent steroid hydroxylases as drug development targets
inferred← citeshttps://doi.org/10.1016/j.phrs.2016.10.001openalex-snapshot
Androgen receptor variation affects prostate cancer progression and drug resistance
inferred← citeshttps://doi.org/10.1016/j.steroids.2005.09.008openalex-snapshot
Neighboring group participation
inferred← citeshttps://doi.org/10.1016/j.steroids.2007.08.004openalex-snapshot
Synthesis and evaluation of novel 17-indazole androstene derivatives designed as CYP17 inhibitors
inferred← citeshttps://doi.org/10.1016/j.steroids.2008.05.010openalex-snapshot
Synthesis of novel C17 steroidal carbamates
inferred← citeshttps://doi.org/10.1016/j.steroids.2008.06.011openalex-snapshot
Neighboring group participation
inferred← citeshttps://doi.org/10.1016/j.steroids.2009.08.001openalex-snapshot
Steroselective synthesis of some steroidal oxazolines, as novel potential inhibitors of 17α-hydroxylase-C17,20-lyase
inferred← citeshttps://doi.org/10.1016/j.steroids.2011.02.009openalex-snapshot
The reaction of azoles with 17-chloro-16-formylandrosta-5,16-dien-3β-yl-acetate: Synthesis and structural elucidation of novel 16-azolylmethylene-17-oxoandrostanes
inferred← citeshttps://doi.org/10.1016/j.steroids.2011.05.015openalex-snapshot
New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors
inferred← citeshttps://doi.org/10.1016/j.steroids.2011.06.002openalex-snapshot
Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): Head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and abiraterone in LAPC-4 human prostate cancer xenograft model
inferred← citeshttps://doi.org/10.1016/j.steroids.2011.07.006openalex-snapshot
Synthesis of steroid–ferrocene conjugates of steroidal 17-carboxamides via a palladium-catalyzed aminocarbonylation – Copper-catalyzed azide–alkyne cycloaddition reaction sequence
inferred← citeshttps://doi.org/10.1016/j.steroids.2011.10.007openalex-snapshot
Synthesis of 21-nitrogen substituted pregna-5,17(20)-dienes from pregnenolone
inferred← citeshttps://doi.org/10.1016/j.steroids.2013.02.014openalex-snapshot
Synthesis and molecular modeling of (4′R)- and (4′S)- 4′-substituted 2′-{[(E)-androst-5-en-17-ylidene]-methyl}oxazolines
inferred← citeshttps://doi.org/10.1016/j.steroids.2014.03.011openalex-snapshot
Synthesis of steroidal and nonsteroidal vicinal heterocyclic alcohols, N-(1-cycloalkenyl)heterocycles and their antibacterial studies
inferred← citeshttps://doi.org/10.1016/j.steroids.2014.07.018openalex-snapshot
Pd-catalyzed steroid reactions
inferred← citeshttps://doi.org/10.1016/j.steroids.2014.12.021openalex-snapshot
CYP17A1 inhibitors in castration-resistant prostate cancer
inferred← citeshttps://doi.org/10.1016/j.steroids.2015.05.002openalex-snapshot
A new pregnenolone analogues as privileged scaffolds in inhibition of CYP17 hydroxylase enzyme. Synthesis and in silico molecular docking study
inferred← citeshttps://doi.org/10.1016/j.steroids.2015.05.011openalex-snapshot
New biaryl-chalcone derivatives of pregnenolone via Suzuki–Miyaura cross-coupling reaction. Synthesis, CYP17 hydroxylase inhibition activity, QSAR, and molecular docking study
inferred← citeshttps://doi.org/10.1016/j.steroids.2015.08.003openalex-snapshot
Efficient synthesis of novel antiproliferative steroidal spirooxindoles via the [3+2] cycloaddition reactions of azomethine ylides
inferred← citeshttps://doi.org/10.1016/j.steroids.2017.05.006openalex-snapshot
Synthesis of 16α-amino-pregnenolone derivatives via ionic liquid-catalyzed aza-Michael addition and their evaluation as C 17,20 -lyase inhibitors
inferred← citeshttps://doi.org/10.1016/j.steroids.2017.11.009openalex-snapshot
Comparison of [17(20)E]-21-Norpregnene oxazolinyl and benzoxazolyl derivatives as inhibitors of CYP17A1 activity and prostate carcinoma cells growth
inferred← citeshttps://doi.org/10.1016/j.steroids.2018.03.006openalex-snapshot
Synthesis of novel 17-triazolyl-androst-5-en-3-ol epimers via Cu(I)-catalyzed azide-alkyne cycloaddition and their inhibitory effect on 17α-hydroxylase/C 17,20 -lyase
inferred← citeshttps://doi.org/10.1016/j.steroids.2019.03.012openalex-snapshot
Synthesis and evaluation of novel D-ring substituted steroidal pyrazolines as potential anti-inflammatory agents
inferred← citeshttps://doi.org/10.1016/j.steroids.2019.108534openalex-snapshot
New steroidal oxazolines, benzoxazoles and benzimidazoles related to abiraterone and galeterone
inferred← citeshttps://doi.org/10.1016/j.steroids.2019.108548openalex-snapshot
Heterocyclic steroids: Efficient routes for annulation of pentacyclic steroidal pyrimidines
inferred← citeshttps://doi.org/10.1016/j.steroids.2022.109062openalex-snapshot
Large-scale synthesis of galeterone and lead next generation galeterone analog VNPP433-3β
inferred← citeshttps://doi.org/10.1016/j.steroids.2023.109184openalex-snapshot
Murine toxicology and pharmacokinetics of lead next generation galeterone analog, VNPP433-3β
inferred← citeshttps://doi.org/10.1016/j.steroids.2024.109475openalex-snapshot
Steroidal 21-imidazolium salt derivatives: Synthesis and anticancer activity
inferred← citeshttps://doi.org/10.1016/j.supflu.2011.07.017openalex-snapshot
5α-Reductase type 1 inhibition of Oryza sativa bran extract prepared by supercritical carbon dioxide fluid
inferred← citeshttps://doi.org/10.1016/j.tet.2017.11.027openalex-snapshot
N,N-dimethyl-d-glucosamine as an efficient ligand for copper-catalyzed Ullmann-type coupling of N-H heterocycles with aryl halides
inferred← citeshttps://doi.org/10.1016/j.tet.2020.131078openalex-snapshot
Synthesis of 1-(2-bromo-1-arylethyl)-1H-benzotriazoles via NBS promoted addition of 1H-benzotriazole to alkene: Relevance in benzotriazole ring cleavage
inferred← citeshttps://doi.org/10.1016/j.tetlet.2014.04.011openalex-snapshot
A facile method for the synthesis of steroidal and nonsteroidal 5-methyl pyrazolo[1,5-a]pyrimidines
inferred← citeshttps://doi.org/10.1016/j.toxrep.2024.101774openalex-snapshot
Polygenic anti-cancer activity of Indigofera macrophylla in prostate cancer induced animal model
inferred← citeshttps://doi.org/10.1016/j.trecan.2015.12.001openalex-snapshot
Targeting Androgen/Estrogen Receptors Crosstalk in Cancer
inferred← citeshttps://doi.org/10.1016/j.urolonc.2008.07.036openalex-snapshot
The Coffey Lecture: Steroidogenic enzyme inhibitors and hormone dependent cancer
inferred← citeshttps://doi.org/10.1016/j.urolonc.2009.03.016openalex-snapshot
Castration-resistant prostate cancer: Targeting androgen metabolic pathways in recurrent disease
inferred← citeshttps://doi.org/10.1016/j.urolonc.2015.05.025openalex-snapshot
Novel and next-generation androgen receptor–directed therapies for prostate cancer: Beyond abiraterone and enzalutamide
inferred← citeshttps://doi.org/10.1016/s0959-8049(11)70164-2openalex-snapshot
Continued targeting of androgen receptor signalling: a rational and efficacious therapeutic strategy in metastatic castration-resistant prostate cancer
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.2c01164openalex-snapshot
Design, Synthesis, and Biological Evaluation of Androgen Receptor Degrading and Antagonizing Bifunctional Steroidal Analogs for the Treatment of Advanced Prostate Cancer
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.8b00419openalex-snapshot
Structure-Based Design of Inhibitors with Improved Selectivity for Steroidogenic Cytochrome P450 17A1 over Cytochrome P450 21A2
inferred← citeshttps://doi.org/10.1021/acs.joc.4c00803openalex-snapshot
Synthesis of N-Alkenylated Heterocycles via T3P-Promoted Condensation with Ketones
inferred← citeshttps://doi.org/10.1021/acs.orglett.6b03030openalex-snapshot
CO 2 as a C1 Source: B(C 6 F 5 ) 3 -Catalyzed Cyclization of o -Phenylene-diamines To Construct Benzimidazoles in the Presence of Hydrosilane
inferred← citeshttps://doi.org/10.1021/acs.orglett.9b01609openalex-snapshot
Chiral Bicyclo[2.2.2]octa-2,5-dienyltrifluoroborate Derivative as a Useful and Stable Precursor of C1-Symmetric Chiral Dienes
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.6b00137openalex-snapshot
Identification of Novel Steroidal Androgen Receptor Degrading Agents Inspired by Galeterone 3β-Imidazole Carbamate
inferred← citeshttps://doi.org/10.1021/ci3002342openalex-snapshot
Modeling Androgen Receptor Flexibility: A Binding Mode Hypothesis of CYP17 Inhibitors/Antiandrogens for Prostate Cancer Therapy
inferred← citeshttps://doi.org/10.1021/ci900247topenalex-snapshot
Classification of Cytochrome P450 Inhibitors with Respect to Binding Free Energy and pIC 50 Using Common Molecular Descriptors
inferred← citeshttps://doi.org/10.1021/jm100317bopenalex-snapshot
Replacement of Imidazolyl by Pyridyl in Biphenylmethylenes Results in Selective CYP17 and Dual CYP17/CYP11B1 Inhibitors for the Treatment of Prostate Cancer
inferred← citeshttps://doi.org/10.1021/jm3004637openalex-snapshot
Selective Dual Inhibitors of CYP19 and CYP11B2: Targeting Cardiovascular Diseases Hiding in the Shadow of Breast Cancer
inferred← citeshttps://doi.org/10.1021/jm400048vopenalex-snapshot
Systematic Structure Modifications of Multitarget Prostate Cancer Drug Candidate Galeterone To Produce Novel Androgen Receptor Down-Regulating Agents as an Approach to Treatment of Advanced Prostate Cancer
inferred← citeshttps://doi.org/10.1021/jm501239fopenalex-snapshot
Discovery and Development of Galeterone (TOK-001 or VN/124-1) for the Treatment of All Stages of Prostate Cancer
inferred← citeshttps://doi.org/10.1021/jm801240dopenalex-snapshot
Structure−Activity Relationship of New Anti-Hepatitis C Virus Agents: Heterobicycle−Coumarin Conjugates
inferred← citeshttps://doi.org/10.1021/jm901061sopenalex-snapshot
4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesufonate) (NSC 88915) and Related Novel Steroid Derivatives as Tyrosyl-DNA Phosphodiesterase (Tdp1) Inhibitors
inferred← citeshttps://doi.org/10.1021/op500044popenalex-snapshot
Improved Procedure for Preparation of Abiraterone Acetate
inferred← citeshttps://doi.org/10.1038/clpt.2011.275openalex-snapshot
Development and Clinical Utility of Abiraterone Acetate as an Androgen Synthesis Inhibitor
inferred← citeshttps://doi.org/10.1038/ncpuro1237openalex-snapshot
CYP17 inhibition as a hormonal strategy for prostate cancer
inferred← citeshttps://doi.org/10.1038/nrclinonc.2011.117openalex-snapshot
The changing therapeutic landscape of castration-resistant prostate cancer
inferred← citeshttps://doi.org/10.1038/nrclinonc.2014.72openalex-snapshot
Evolution of androgen receptor targeted therapy for advanced prostate cancer
inferred← citeshttps://doi.org/10.1038/nrurol.2013.274openalex-snapshot
CYP17 inhibitors—abiraterone, C17,20-lyase inhibitors and multi-targeting agents
inferred← citeshttps://doi.org/10.1038/nrurol.2017.132openalex-snapshot
The influence of steroid metabolism on CYP17A1 inhibitor activity
inferred← citeshttps://doi.org/10.1038/onc.2014.115openalex-snapshot
Targeting the androgen receptor pathway in castration-resistant prostate cancer: progresses and prospects
inferred← citeshttps://doi.org/10.1038/pcan.2011.24openalex-snapshot
Emerging therapeutic approaches in the management of metastatic castration-resistant prostate cancer
inferred← citeshttps://doi.org/10.1038/s41419-020-2385-4openalex-snapshot
Active steroid hormone synthesis renders adrenocortical cells highly susceptible to type II ferroptosis induction
inferred← citeshttps://doi.org/10.1038/sj.bjc.6604904openalex-snapshot
CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer
inferred← citeshttps://doi.org/10.1038/sj.bjc.6605882openalex-snapshot
Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR
inferred← citeshttps://doi.org/10.1038/srep32654openalex-snapshot
Peptidomimetics Based On Dehydroepiandrosterone Scaffold: Synthesis, Antiproliferation Activity, Structure-Activity Relationship, and Mechanisms
inferred← citeshttps://doi.org/10.1039/c2np20082aopenalex-snapshot
Anticancer steroids: linking natural and semi-synthetic compounds
inferred← citeshttps://doi.org/10.1039/c4ob00404copenalex-snapshot
Synthesis of novel 1,2,3-triazolyl derivatives of pregnane, androstane and d -homoandrostane. Tandem “click” reaction/Cu-catalyzed d -homo rearrangement
inferred← citeshttps://doi.org/10.1039/c5md00371gopenalex-snapshot
1,3,4-Oxadiazole derivatives as potential antitumor agents: discovery, optimization and biological activity valuation
inferred← citeshttps://doi.org/10.1039/c6np00107fopenalex-snapshot
The synthesis of cardenolide and bufadienolide aglycones, and related steroids bearing a heterocyclic subunit
inferred← citeshttps://doi.org/10.1039/c7gc00901aopenalex-snapshot
Microwave-assisted solid phase diazotation: a method for the environmentally benign synthesis of benzotriazoles
inferred← citeshttps://doi.org/10.1039/d1ra07613bopenalex-snapshot
Novel alkylaminoethyl derivatives of androstane 3-oximes as anticancer candidates: synthesis and evaluation of cytotoxic effects
inferred← citeshttps://doi.org/10.1039/d5md00954eopenalex-snapshot
Strategies to inhibit steroid cytochrome P450 enzymes to benefit human health: development of steroid ligands for P450s 17A1, 19A1, and 8B1 to treat cancer and obesity
inferred← citeshttps://doi.org/10.1074/jbc.m111.261933openalex-snapshot
Direct Regulation of Androgen Receptor Activity by Potent CYP17 Inhibitors in Prostate Cancer Cells
inferred← citeshttps://doi.org/10.1074/jbc.m114.608919openalex-snapshot
Catalytically Relevant Electrostatic Interactions of Cytochrome P450c17 (CYP17A1) and Cytochrome b5
inferred← citeshttps://doi.org/10.1080/03602532.2018.1483401openalex-snapshot
Human cytochrome P450 enzymes 5–51 as targets of drugs and natural and environmental compounds: mechanisms, induction, and inhibition – toxic effects and benefits
inferred← citeshttps://doi.org/10.1080/10406638.2019.1665554openalex-snapshot
UV Light Mediated Palladium-Catalyzed Synthesis of 2-Substituedpyrido[2,3- d ]pyrimidines
inferred← citeshttps://doi.org/10.1080/10406638.2020.1716029openalex-snapshot
Ultrasound-Assisted Preparation of Cu-Doped TiO2 Nanoparticles as a Nanocatalyst for Sonochemical Synthesis of Pyridopyrimidines
inferred← citeshttps://doi.org/10.1080/14656566.2018.1548611openalex-snapshot
Perspectives on the current and emerging chemical androgen receptor antagonists for the treatment of prostate cancer
inferred← citeshttps://doi.org/10.1088/1742-6596/1294/5/052023openalex-snapshot
Synthesis, Characterization and biological Study of some new derivatives from Pregnenolone via McMurry reaction
inferred← citeshttps://doi.org/10.1088/1742-6596/1853/1/012057openalex-snapshot
Synthesis of steroid bearing heterocyclic derivatives and biological activity. Review 2014-2020
inferred← citeshttps://doi.org/10.1097/ppo.0000000000000214openalex-snapshot
Androgen Receptor and Beyond, Targeting Androgen Signaling in Castration-Resistant Prostate Cancer
inferred← citeshttps://doi.org/10.1107/s0108270108005842openalex-snapshot
1H-Indazole and 2H-indazole derivatives of androsta-5,16-dien-3β-ol
inferred← citeshttps://doi.org/10.1107/s0108270108025997openalex-snapshot
Conformation of 17-chloro-16-formylandrosta-5,16-dien-3β-yl acetate and 17-chloroandrosta-5,16-dien-3β-yl acetate
inferred← citeshttps://doi.org/10.1111/cbdd.12195openalex-snapshot
N‐substituted Piperazinopyridylsteroid Derivatives as Abiraterone Analogues Inhibit Growth and Induce Pro‐apoptosis in Human Hormone‐independent Prostate Cancer Cell Lines
inferred← citeshttps://doi.org/10.1111/fcp.12607openalex-snapshot
Interactions of galeterone and its 3‐keto‐Δ4 metabolite (D4G) with one of the key enzymes of corticosteroid biosynthesis – steroid 21‐monooxygenase (CYP21A2)
inferred← citeshttps://doi.org/10.1111/j.1582-4934.2009.00957.xopenalex-snapshot
Serially heterotransplanted human prostate tumours as an experimental model
inferred← citeshttps://doi.org/10.1124/dmd.109.031351openalex-snapshot
Targeting Drug-Metabolizing Enzymes for Effective Chemoprevention and Chemotherapy
inferred← citeshttps://doi.org/10.1124/dmd.117.075317openalex-snapshot
Structural and Functional Evaluation of Clinically Relevant Inhibitors of Steroidogenic Cytochrome P450 17A1
inferred← citeshttps://doi.org/10.1134/s0006297909130057openalex-snapshot
From structure and functions of steroidogenic enzymes to new technologies of gene engineering
inferred← citeshttps://doi.org/10.1134/s1068162020050039openalex-snapshot
Synthesis, In Vitro Anti-HIV Activity, Cytotoxicity, and Computational Studies of Some New Steroids and Their Pyrazoline and Oxime Analogues
inferred← citeshttps://doi.org/10.1134/s1990750811010124openalex-snapshot
Screening of potential substrates or inhibitors of cytochrome P450 17A1 (CYP17A1) by electrochemical methods
inferred← citeshttps://doi.org/10.1155/2022/4993405openalex-snapshot
Cytotoxic Action of Palladium-Based Compound on Prostate Stem Cells, Primary Prostate Epithelial Cells, Prostate Epithelial Cells, and Prostate Cell Lines
inferred← citeshttps://doi.org/10.1158/0008-5472.can-11-3980openalex-snapshot
Interactions of Abiraterone, Eplerenone, and Prednisolone with Wild-type and Mutant Androgen Receptor: A Rationale for Increasing Abiraterone Exposure or Combining with MDV3100
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-10-0567openalex-snapshot
New Strategies in Metastatic Prostate Cancer: Targeting the Androgen Receptor Signaling Pathway
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-12-3601openalex-snapshot
Molecular Pathways: Targeting Resistance in the Androgen Receptor for Therapeutic Benefit
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-14-0292openalex-snapshot
Galeterone Prevents Androgen Receptor Binding to Chromatin and Enhances Degradation of Mutant Androgen Receptor
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-15-1432openalex-snapshot
Androgen Receptor Modulation Optimized for Response (ARMOR) Phase I and II Studies: Galeterone for the Treatment of Castration-Resistant Prostate Cancer
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-07-0581openalex-snapshot
Synergistic effect of a novel antiandrogen, VN/124-1, and signal transduction inhibitors in prostate cancer progression to hormone independence in vitro
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-08-0230openalex-snapshot
Androgen receptor inactivation contributes to antitumor efficacy of 17α-hydroxylase/17,20-lyase inhibitor 3β-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-08-0336openalex-snapshot
17α-Hydroxylase/17,20 lyase inhibitor VN/124-1 inhibits growth of androgen-independent prostate cancer cells via induction of the endoplasmic reticulum stress response
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-14-0521openalex-snapshot
Anticancer Activity of a Novel Selective CYP17A1 Inhibitor in Preclinical Models of Castrate-Resistant Prostate Cancer
inferred← citeshttps://doi.org/10.1172/jci87328openalex-snapshot
Androgen receptor antagonism drives cytochrome P450 17A1 inhibitor efficacy in prostate cancer
inferred← citeshttps://doi.org/10.1177/1756287212452196openalex-snapshot
Abiraterone and other novel androgen-directed strategies for the treatment of prostate cancer: a new era of hormonal therapies is born
inferred← citeshttps://doi.org/10.1177/1758834012458137openalex-snapshot
The changing landscape in the treatment of metastatic castration-resistant prostate cancer
inferred← citeshttps://doi.org/10.1186/1471-2105-9-411openalex-snapshot
Classification of drug molecules considering their IC50 values using mixed-integer linear programming based hyper-boxes method
inferred← citeshttps://doi.org/10.1186/1471-2407-10-244openalex-snapshot
Estradiol suppresses tissue androgens and prostate cancer growth in castration resistant prostate cancer
inferred← citeshttps://doi.org/10.1186/2193-1801-3-574openalex-snapshot
Increased expression of CYP17A1 indicates an effective targeting of the androgen receptor axis in castration resistant prostate cancer (CRPC)
inferred← citeshttps://doi.org/10.1248/cpb.60.449openalex-snapshot
The Reactivity of Gem Cyanoester Ketene Dithiolates towards the Development of Potent Antioxidant Heterocycles
inferred← citeshttps://doi.org/10.14288/1.0072850openalex-snapshot
Inhibition of castration resistant prostate cancer by sintokamide A : an antagonist of the amino-terminus of the androgen receptor
inferred← citeshttps://doi.org/10.14310/horm.2002.1406openalex-snapshot
Androgen receptors in early and castration resistant prostate cancer: friend or foe?
inferred← citeshttps://doi.org/10.1517/13543781003639427openalex-snapshot
Abiraterone acetate for castration resistant prostate cancer
inferred← citeshttps://doi.org/10.1517/13543784.2010.494178openalex-snapshot
New agents and strategies for the hormonal treatment of castration-resistant prostate cancer
inferred← citeshttps://doi.org/10.1517/13543784.2014.885950openalex-snapshot
Targeting metastatic castration-resistant prostate cancer: mechanisms of progression and novel early therapeutic approaches
inferred← citeshttps://doi.org/10.1517/13543784.2016.1162784openalex-snapshot
Phase I and II therapies targeting the androgen receptor for the treatment of castration resistant prostate cancer
inferred← citeshttps://doi.org/10.1517/17460441.2.10.1341openalex-snapshot
Perspectives on designs of antiandrogens for prostate cancer
inferred← citeshttps://doi.org/10.15252/emmm.201303701openalex-snapshot
Targeting the adaptive molecular landscape of castration‐resistant prostate cancer
inferred← citeshttps://doi.org/10.1530/ec-17-0118openalex-snapshot
Clinical relevance of androgen receptor alterations in prostate cancer
inferred← citeshttps://doi.org/10.1530/erc-16-0298openalex-snapshot
Emerging data on androgen receptor splice variants in prostate cancer
inferred← citeshttps://doi.org/10.1586/14737140.8.9.1495openalex-snapshot
Androgen receptor: role and novel therapeutic prospects in prostate cancer
inferred← citeshttps://doi.org/10.1586/eem.10.49openalex-snapshot
Molecular processes leading to aberrant androgen receptor signaling and castration resistance in prostate cancer
showing the first 200 of 245 · page through all 245
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.