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Structure−Brain Exposure Relationships
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1098-1128(200009)20:5<367::aid-med3>3.0.co;2-popenalex-snapshot
Targeting drugs to the brain by redox chemical delivery systems
inferredcites →https://doi.org/10.1002/1520-6017(200011)89:11<1371::aid-jps1>3.0.co;2-dopenalex-snapshot
Transporter-Mediated Permeation of Drugs Across the Blood–Brain Barrier
inferredcites →https://doi.org/10.1002/anie.199700241openalex-snapshot
Transport and Detoxication: Principles, Approaches, and Perspectives for Research on the Blood – Brain Barrier
inferredcites →https://doi.org/10.1002/jps.10424openalex-snapshot
Blood–Brain Barrier Efflux Transport
inferredcites →https://doi.org/10.1002/jps.2600610420openalex-snapshot
Relationship between Lipophilic Character and Anesthetic Activity
inferredcites →https://doi.org/10.1002/jps.2600760902openalex-snapshot
Hydrophobicity and Central Nervous System Agents: On the Principle of Minimal Hydrophobicity in Drug Design
inferredcites →https://doi.org/10.1007/978-3-0348-8049-7openalex-snapshot
Peptide Transport and Delivery into the Central Nervous System
inferredcites →https://doi.org/10.1016/0092-8674(94)90212-7openalex-snapshot
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
inferredcites →https://doi.org/10.1016/0165-0173(91)90020-9openalex-snapshot
Drug metabolizing enzymes in the brain and cerebral microvessels
inferredcites →https://doi.org/10.1016/0169-409x(95)00106-hopenalex-snapshot
Prodrugs for improved CNS delivery
inferredcites →https://doi.org/10.1016/0730-725x(96)00022-7openalex-snapshot
A spatiotemporal study on the distribution of intraperitoneally injected nitroxide radical in the rat head using an in vivo ESR imaging system
inferredcites →https://doi.org/10.1016/0969-8051(94)90080-9openalex-snapshot
Synthesis of n.c.a. carbon-11 labelled clozapine and its major metabolite clozapine-N-oxide and comparison of their biodistribution in mice
inferredcites →https://doi.org/10.1016/j.bmc.2004.07.043openalex-snapshot
Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules
inferredcites →https://doi.org/10.1016/j.bmc.2004.10.033openalex-snapshot
N-Oxide analogs of WAY-100635: new high affinity 5-HT1A receptor antagonists
inferredcites →https://doi.org/10.1016/j.bmc.2005.01.061openalex-snapshot
In silico ADME modelling: prediction models for blood–brain barrier permeation using a systematic variable selection method
inferredcites →https://doi.org/10.1016/j.bmcl.2003.10.074openalex-snapshot
Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release
inferredcites →https://doi.org/10.1016/j.bmcl.2004.04.091openalex-snapshot
(+)-3-[2-(Benzo[b]thiophen-2-yl)-2-oxoethyl]-1-azabicyclo[2.2.2]octane as potent agonists for the α7 nicotinic acetylcholine receptor
inferredcites →https://doi.org/10.1016/j.bmcl.2005.06.017openalex-snapshot
Benzazoles as allosteric potentiators of metabotropic glutamate receptor 2 (mGluR2): Efficacy in an animal model for schizophrenia
inferredcites →https://doi.org/10.1016/j.bmcl.2005.06.107openalex-snapshot
Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT6 receptor antagonists
inferredcites →https://doi.org/10.1016/j.ejmech.2003.12.004openalex-snapshot
The factors that influence permeation across the blood–brain barrier
inferredcites →https://doi.org/10.1016/j.ijpharm.2004.10.007openalex-snapshot
Evaluation of the MDR-MDCK cell line as a permeability screen for the blood–brain barrier
inferredcites →https://doi.org/10.1016/j.lfs.2005.04.075openalex-snapshot
Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: Dopamine D2, serotonin 2A and NK-1 receptors as examples
inferredcites →https://doi.org/10.1016/j.mibio.2003.09.009openalex-snapshot
Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography
inferredcites →https://doi.org/10.1016/j.pneurobio.2005.04.006openalex-snapshot
Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases
inferredcites →https://doi.org/10.1016/j.tips.2004.06.002openalex-snapshot
Importance of P-glycoprotein at blood–tissue barriers
inferredcites →https://doi.org/10.1016/j.tiv.2004.06.011openalex-snapshot
In vitro models for the blood–brain barrier
inferredcites →https://doi.org/10.1016/s0006-2952(99)00031-3openalex-snapshot
Investigation into the correlation between the structure of hydroxypyridinones and blood–brain barrier permeability
inferredcites →https://doi.org/10.1016/s0022-3565(24)34867-0openalex-snapshot
Efflux Transport of a New Quinolone Antibacterial Agent, HSR-903, across the Blood-Brain Barrier
inferredcites →https://doi.org/10.1016/s0169-409x(00)00139-3openalex-snapshot
Delivery of peptides and proteins through the blood–brain barrier
inferredcites →https://doi.org/10.1016/s0169-409x(98)00084-2openalex-snapshot
Carrier-mediated or specialized transport of drugs across the blood–brain barrier
inferredcites →https://doi.org/10.1016/s0378-5173(03)00372-7openalex-snapshot
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs
inferredcites →https://doi.org/10.1016/s0730-725x(00)00183-1openalex-snapshot
In vivo EPR imaging by using an acyl-protected hydroxylamine to analyze intracerebral oxidative stress in rats after epileptic seizures
inferredcites →https://doi.org/10.1016/s0731-7085(01)00542-8openalex-snapshot
Comparison of in vitro BBMEC permeability and in vivo CNS uptake by microdialysis sampling
inferredcites →https://doi.org/10.1016/s0928-0987(00)00177-9openalex-snapshot
Structure–activity relationship of P-glycoprotein substrates and modifiers
inferredcites →https://doi.org/10.1016/s0960-894x(01)00343-2openalex-snapshot
1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor
inferredcites →https://doi.org/10.1016/s0960-894x(02)00172-5openalex-snapshot
Bicyclic piperazinylbenzenesulphonamides are potent and selective 5-HT6 receptor antagonists
inferredcites →https://doi.org/10.1016/s1056-8719(00)00107-6openalex-snapshot
Drug-like properties and the causes of poor solubility and poor permeability
inferredcites →https://doi.org/10.1016/s1359-6446(03)02827-7openalex-snapshot
In silico prediction of blood–brain barrier permeation
inferredcites →https://doi.org/10.1016/s1359-6446(03)02858-7openalex-snapshot
New approaches to in vitro models of blood–brain barrier drug transport
inferredcites →https://doi.org/10.1021/bi026888gopenalex-snapshot
Notch and the Amyloid Precursor Protein Are Cleaved by Similar γ-Secretase(s)
inferredcites →https://doi.org/10.1021/jm000090iopenalex-snapshot
Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat
inferredcites →https://doi.org/10.1021/jm00020a001openalex-snapshot
A New Paclitaxel Photoaffinity Analog with a 3-(4-Benzoylphenyl)propanoyl Probe for Characterization of Drug-Binding Sites on Tubulin and P-Glycoprotein
inferredcites →https://doi.org/10.1021/jm00032a017openalex-snapshot
Enhanced Brain Delivery of an Anti-HIV Nucleoside 2'-F-ara-ddI by Xanthine Oxidase Mediated Biotransformation
inferredcites →https://doi.org/10.1021/jm000478dopenalex-snapshot
Hydrophilic, Pro-Drug Analogues of T138067 Are Efficacious in Controlling Tumor Growth In Vivo and Show a Decreased Ability To Cross the Blood Brain Barrier
inferredcites →https://doi.org/10.1021/jm00398a028openalex-snapshot
Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists
inferredcites →https://doi.org/10.1021/jm00398a029openalex-snapshot
Renin inhibitors containing .psi.[CH2O] pseudopeptide inserts
inferredcites →https://doi.org/10.1021/jm0105169openalex-snapshot
Acyl-Protected Hydroxylamines as Spin Label Generators for EPR Brain Imaging
inferredcites →https://doi.org/10.1021/jm015556ropenalex-snapshot
Design, Synthesis and Activity of Ascorbic Acid Prodrugs of Nipecotic, Kynurenic and Diclophenamic Acids, Liable to Increase Neurotropic Activity
inferredcites →https://doi.org/10.1021/jm040066vopenalex-snapshot
Discovering Drugs through Biological Transformation: Role of Pharmacologically Active Metabolites in Drug Discovery
inferredcites →https://doi.org/10.1021/jm040082sopenalex-snapshot
β-Oxygenated Analogues of the 5-HT2ASerotonin Receptor Agonist 1-(4-Bromo-2,5-dimethoxyphenyl)-2-aminopropane
inferredcites →https://doi.org/10.1021/jm040114bopenalex-snapshot
Chemical Modification of Paclitaxel (Taxol) Reduces P-Glycoprotein Interactions and Increases Permeation across the Blood−Brain Barrier in Vitro and in Situ
inferredcites →https://doi.org/10.1021/jm0491086openalex-snapshot
Novel Cyclopropyl β-Amino Acid Analogues of Pregabalin and Gabapentin That Target the α2-δ Protein
inferredcites →https://doi.org/10.1021/jm049188dopenalex-snapshot
Discovery of the α7 Nicotinic Acetylcholine Receptor Agonists. (R)-3‘-(5-Chlorothiophen-2-yl)spiro-1-azabicyclo[2.2.2]octane-3,5‘-[1‘,3‘]oxazolidin-2‘-one as a Novel, Potent, Selective, and Orally Bioavailable Ligand
inferredcites →https://doi.org/10.1021/jm0502541openalex-snapshot
Synthesis and Biological Activity of Flurbiprofen Analogues as Selective Inhibitors of β-Amyloid1-42Secretion
inferredcites →https://doi.org/10.1021/jm9505122openalex-snapshot
High-Affinity Inhibitors of Dihydrofolate Reductase: Antimicrobial and Anticancer Activities of 7,8-Dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with Small Molecular Size
inferredcites →https://doi.org/10.1021/jm9506736openalex-snapshot
Controlled Modification of Acidity in Cholecystokinin B Receptor Antagonists: N-(1,4-Benzodiazepin-3-yl)-N ‘-[3-(tetrazol-5-ylamino)phenyl]ureas
inferredcites →https://doi.org/10.1021/jm960140copenalex-snapshot
In Vitro and in Vivo Evaluation of 6-Azido-2‘,3‘-dideoxy-2‘-fluoro-β- d -arabinofuranosylpurine and N6-Methyl-2‘,3‘-dideoxy-2‘-fluoro-β- d -arabinofuranosyladenine as Prodrugs of the Anti-HIV Nucleosides 2‘-F-ara-ddA and 2‘-F-ara-ddI
inferredcites →https://doi.org/10.1021/jm960339popenalex-snapshot
Synthesis, Biotransformation, and Pharmacokinetic Studies of 9-(β- d -Arabinofuranosyl)-6-azidopurine: A Prodrug for Ara-A Designed To Utilize the Azide Reduction Pathway
inferredcites →https://doi.org/10.1021/jm970065lopenalex-snapshot
Second Generation “Peptoid” CCK-B Receptor Antagonists: Identification and Development ofN-(Adamantyloxycarbonyl)-α-methyl-(R)-tryptophan Derivative (CI-1015) with an Improved Pharmacokinetic Profile
inferredcites →https://doi.org/10.1021/jm970376wopenalex-snapshot
Novel and Highly Potent 5-HT3 Receptor Agonists Based on a Pyrroloquinoxaline Structure
inferredcites →https://doi.org/10.1021/jm980532eopenalex-snapshot
5-Chloro-N-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): A Potent, Selective, and Orally Bioavailable 5-HT6 Receptor Antagonist
inferredcites →https://doi.org/10.1021/jm990957gopenalex-snapshot
Indeno[1,2-b]pyrazin-2,3-diones: A New Class of Antagonists at the Glycine Site of the NMDA Receptor with Potent in Vivo Activity
inferredcites →https://doi.org/10.1023/a:1007522626070openalex-snapshot
Evaluation of Blood-Brain Barrier Passage of a Muscarine M1 Agonist and a Series of Analogous Tetrahydropyridines Measured by In Vivo Microdialysis
inferredcites →https://doi.org/10.1023/a:1011904311149openalex-snapshot
Potential of Immobilized Artificial Membranes for Predicting Drug Penetration Across the Blood−Brain Barrier
inferredcites →https://doi.org/10.1023/a:1016462205267openalex-snapshot
Prediction of Drug Transport Through the Blood-Brain Barrier in Vivo: A Comparison Between Two in Vitro Cell Models
inferredcites →https://doi.org/10.1038/nature03193openalex-snapshot
Navigating chemical space for biology and medicine
inferredcites →https://doi.org/10.1038/nm1112openalex-snapshot
Nonsteroidal anti-inflammatory drugs lower Aβ42 and change presenilin 1 conformation
inferredcites →https://doi.org/10.1038/npp.1993.50openalex-snapshot
Tissue Concentrations of Clozapine and its Metabolites in the Rat
inferredcites →https://doi.org/10.1039/b415090bopenalex-snapshot
Substituted thiazolamide coupled to a redox delivery system: a new γ-secretase inhibitor with enhanced pharmacokinetic profile
inferredcites →https://doi.org/10.1080/10629360412331319817openalex-snapshot
3D QSAR investigation of the blood–brain barrier penetration of chemical compounds
inferredcites →https://doi.org/10.1111/j.2042-7158.1997.tb06072.xopenalex-snapshot
Molecular Factors Influencing Drug Transfer across the Blood-Brain Barrier
inferredcites →https://doi.org/10.1124/dmd.104.001222openalex-snapshot
RELATIONSHIP BETWEEN EXPOSURE AND NONSPECIFIC BINDING OF THIRTY-THREE CENTRAL NERVOUS SYSTEM DRUGS IN MICE
inferredcites →https://doi.org/10.1124/dmd.104.001230openalex-snapshot
THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL
inferredcites →https://doi.org/10.1124/jpet.102.045856openalex-snapshot
Active Transport of High-Affinity Choline and Nicotine Analogs into the Central Nervous System by the Blood-Brain Barrier Choline Transporter
inferredcites →https://doi.org/10.1124/jpet.104.075705openalex-snapshot
In Silico Predictions of Blood-Brain Barrier Penetration: Considerations to “Keep in Mind”
inferredcites →https://doi.org/10.1124/jpet.105.092916openalex-snapshot
Improving the in Vitro Prediction of in Vivo Central Nervous System Penetration: Integrating Permeability, P-glycoprotein Efflux, and Free Fractions in Blood and Brain
inferredcites →https://doi.org/10.1124/mi.3.2.90openalex-snapshot
BLOOD-BRAIN BARRIER DRUG TARGETING: THE FUTURE OF BRAIN DRUG DEVELOPMENT
inferredcites →https://doi.org/10.1126/science.128.3338.1572-aopenalex-snapshot
Salt Excretion by Nasal Gland of Laysan and Black-Footed Albatrosses
inferredcites →https://doi.org/10.1126/science.128.3338.1574openalex-snapshot
Acute Infection of Mice with Smith Strain of Staphylococcus aureus
inferredcites →https://doi.org/10.1146/annurev.pharmtox.43.100901.140204openalex-snapshot
The Role of Drug Transporters at the Blood-Brain Barrier
inferredcites →https://doi.org/10.1172/jci18162openalex-snapshot
NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo
inferredcites →https://doi.org/10.1201/9780367800529openalex-snapshot
The Blood-Brain Barrier and Drug Delivery to the CNS
inferredcites →https://doi.org/10.1602/neurorx.2.1.54openalex-snapshot
Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems
inferredcites →https://doi.org/10.1602/neurorx.2.1.73openalex-snapshot
Active efflux across the blood-brain barrier: Role of the solute carrier family
inferredcites →https://doi.org/10.1602/neurorx.2.1.86openalex-snapshot
Blood-brain barrier active efflux transporters: ATP-binding cassette gene family
inferredcites →https://doi.org/10.2174/0929867043365071openalex-snapshot
In Silico Prediction Models for Blood-Brain Barrier Permeation
inferredcites →https://doi.org/10.2174/1381612043384844openalex-snapshot
ABC Transporters and the Blood-Brain Barrier
inferredcites →https://doi.org/10.3109/10611860008997913openalex-snapshot
Improved Brain Delivery of a Nonsteroidal Anti-Inflammatory Drug with a Synthetic Glyceride Ester: a Preliminary Attempt at a CNS Drug Delivery System for the Therapy of Alzheimer's Disease
inferredcites →https://doi.org/10.3109/10611869808997889openalex-snapshot
Estimation of Blood-Brain Barrier Crossing of Drugs Using Molecular Size and Shape, and H-Bonding Descriptors
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Understanding the Anti-Inflammatory and Anti-Carcinogenic Insights of Terpenoid Compounds from Tinospora Cordifolia: A Molecular Docking Approach
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Blood‐Brain Barrier, Considerations in Drug Development and Delivery
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Blood‐Brain Barrier: Considerations in Drug Development and Delivery
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Case Studies of CNS Drug Optimization—Medicinal Chemistry and CNS Biology Perspectives
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Harnessing Intramolecular Rotation To Enhance Two‐photon Imaging of Aβ Plaques through Minimizing Background Fluorescence
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Near‐Infrared Aggregation‐Induced Emission Luminogens for In Vivo Theranostics of Alzheimer's Disease
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A Photoacoustic Probe with Blood‐Brain Barrier Crossing Ability for Imaging Oxidative Stress Dynamics in the Mouse Brain
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Aminoalkyl Derivatives of 8‐Alkoxypurine‐2,6‐diones: Multifunctional 5‐HT1A/5‐HT7 Receptor Ligands and PDE Inhibitors with Antidepressant Activity
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N‐Substituted Nipecotic Acids as (S)‐SNAP‐5114 Analogues with Modified Lipophilic Domains
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inferred← citeshttps://doi.org/10.1002/jcb.27033openalex-snapshot
Computational discovery of potent drugs to improve the treatment of pyrazinamide resistant Mycobacterium tuberculosis mutants
inferred← citeshttps://doi.org/10.1002/jcb.28461openalex-snapshot
Molecular interaction of investigational ligands with human brain acetylcholinesterase
inferred← citeshttps://doi.org/10.1002/jimd.12570openalex-snapshot
Relief of CoA sequestration and restoration of mitochondrial function in a mouse model of propionic acidemia
inferred← citeshttps://doi.org/10.1002/jlcr.3521openalex-snapshot
Synthesis of S‐2‐((S)‐3‐(4‐chlorophenyl)‐N'‐((4‐chlorophenyl)sulfonyl)‐4‐phenyl‐4,5‐dihydro‐1H‐pyrazole‐1‐carboximidamido)‐3‐(methyl‐d3)butanamide‐d5, octadeuterated JD5037
inferred← citeshttps://doi.org/10.1002/jlcr.4019openalex-snapshot
Strategies for designing novel positron emission tomography (PET) radiotracers to cross the blood–brain barrier
inferred← citeshttps://doi.org/10.1002/jps.21580openalex-snapshot
Comparison of blood–brain barrier permeability assays: in situ brain perfusion, MDR1-MDCKII and PAMPA-BBB
inferred← citeshttps://doi.org/10.1002/jps.21745openalex-snapshot
In vivo, in vitro and in silico methods for small molecule transfer across the BBB
inferred← citeshttps://doi.org/10.1002/masy.202200108openalex-snapshot
Molecular Docking and ADMET Study of Spice‐Derived Potential Phytochemicals against Human DNA Topoisomerase III Alpha
inferred← citeshttps://doi.org/10.1002/mds.28642openalex-snapshot
Rational Design of Novel Therapies for Pantothenate Kinase–Associated Neurodegeneration
inferred← citeshttps://doi.org/10.1002/med.21923openalex-snapshot
Recent advances in dopamine D 2 receptor ligands in the treatment of neuropsychiatric disorders
inferred← citeshttps://doi.org/10.1002/minf.201800126openalex-snapshot
Prediction of Ligands Binding Acetylcholinesterase with Potential Antidotal Activity: A Virtual Screening Approach
inferred← citeshttps://doi.org/10.1002/slct.202203877openalex-snapshot
Propitious Indazole Compounds as β‐ketoacyl‐ACP Synthase Inhibitors and Mechanisms Unfolded for TB Cure: Integrated Rational Design and MD Simulations
inferred← citeshttps://doi.org/10.1002/slct.202204536openalex-snapshot
Synthesis of Functionalized 2′,5‐Oxo‐spiro[furan‐2,3′‐indoline]‐3‐carboxylate Derivatives as Antiproliferative Agents: ADMET Studies, and Molecular Docking against P2Y12 Inhibitors
inferred← citeshttps://doi.org/10.1002/slct.202303089openalex-snapshot
Discovery of Hydrazone Scaffolds as Potent and Selective Multitarget‐Directed Ligands for the Treatment of Neurodegenerative Disorders
inferred← citeshttps://doi.org/10.1002/slct.202404547openalex-snapshot
Oxalis corniculata ‐Derived Bioactive Compounds Target Hormone Receptors in Breast Cancer: HPLC‐ESI‐MS/MS Analysis, Cytotoxicity, and Computational Studies
inferred← citeshttps://doi.org/10.1002/slct.202502622openalex-snapshot
Natural Compounds from Dillenia indica Target Hormonal and Non‐Hormonal Receptors in Triple‐Negative Breast Cancer: A Computational Analysis
inferred← citeshttps://doi.org/10.1002/slct.202505570openalex-snapshot
Delivery and Developmental Strategies for Enhanced Blood–Brain Barrier Permeation—A Review
inferred← citeshttps://doi.org/10.1002/slct.73117openalex-snapshot
Coumarin‐Based Azo Derivatives With Trifluoromethyl Substituents: A Combined Experimental and Computational Approach Toward Novel Anticancer Agents
inferred← citeshttps://doi.org/10.1007/128_2010_74openalex-snapshot
Opioids in Preclinical and Clinical Trials
inferred← citeshttps://doi.org/10.1007/7355_2010_10openalex-snapshot
The Role of Histone Deacetylases in Neurodegenerative Diseases and Small-Molecule Inhibitors as a Potential Therapeutic Approach
inferred← citeshttps://doi.org/10.1007/7355_2013_29openalex-snapshot
The Influence of Bioisosteres in Drug Design: Tactical Applications to Address Developability Problems
inferred← citeshttps://doi.org/10.1007/978-1-4419-1087-5_5openalex-snapshot
Preclinical Development for Suspensions
inferred← citeshttps://doi.org/10.1007/978-1-4614-9105-7_10openalex-snapshot
Drug Discovery Methods for Studying Brain Drug Delivery and Distribution
inferred← citeshttps://doi.org/10.1007/978-1-4614-9105-7_11openalex-snapshot
Prediction of Drug Exposure in the Brain from the Chemical Structure
inferred← citeshttps://doi.org/10.1007/978-3-030-73317-9_108-1openalex-snapshot
In Silico ADME Modeling
inferred← citeshttps://doi.org/10.1007/978-3-030-88773-5_13openalex-snapshot
Drug Discovery Methods for Studying Brain Drug Delivery and Distribution
inferred← citeshttps://doi.org/10.1007/978-3-030-88773-5_14openalex-snapshot
Prediction of Drug Exposure in the Brain from the Chemical Structure
inferred← citeshttps://doi.org/10.1007/978-3-031-35529-5_108openalex-snapshot
In Silico ADME Modeling
inferred← citeshttps://doi.org/10.1007/978-3-031-39171-2_22openalex-snapshot
Inhibitors of Oxytosis/Ferroptosis: A New Class of Therapeutics for Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1007/978-3-031-62604-3_4openalex-snapshot
In Silico Prediction of CNS Bioavailability
inferred← citeshttps://doi.org/10.1007/978-3-319-19144-7_5openalex-snapshot
Antitumor Essential Oils: Progress in Medicinal Chemistry
inferred← citeshttps://doi.org/10.1007/978-3-319-50042-3_6openalex-snapshot
Integrated Lead Optimization: Translational Models as We Advance Toward the Clinic
inferred← citeshttps://doi.org/10.1007/978-3-319-56850-8_4openalex-snapshot
Structural, Physicochemical and Stereochemical Interpretation of QSAR Models Based on Simplex Representation of Molecular Structure
inferred← citeshttps://doi.org/10.1007/s00044-020-02596-3openalex-snapshot
Fusaric acid and derivatives as novel antimicrobial agents
inferred← citeshttps://doi.org/10.1007/s00044-021-02799-2openalex-snapshot
Identification and evaluation of natural organosulfur compounds as potential dual inhibitors of α-amylase and α-glucosidase activity: an in-silico and in-vitro approach
inferred← citeshttps://doi.org/10.1007/s00044-023-03073-3openalex-snapshot
Harnessing the necessary nitrogen atom in chemical biology and drug discovery
inferred← citeshttps://doi.org/10.1007/s00044-025-03433-1openalex-snapshot
Identification of N-(Alkyl)-4-phenylpiperidines as Anti-Neuroinflammatory Agents
inferred← citeshttps://doi.org/10.1007/s00204-021-03083-3openalex-snapshot
An updated review on synthetic cathinones
inferred← citeshttps://doi.org/10.1007/s00204-026-04374-3openalex-snapshot
Multidimensional modeling reveals drivers of neonicotinoids penetration across the human blood-cerebrospinal fluid barrier
inferred← citeshttps://doi.org/10.1007/s00213-012-2817-7openalex-snapshot
The PDE5 inhibitor vardenafil does not affect auditory sensory gating in rats and humans
inferred← citeshttps://doi.org/10.1007/s00213-013-3108-7openalex-snapshot
Mephedrone pharmacokinetics after intravenous and oral administration in rats: relation to pharmacodynamics
inferred← citeshttps://doi.org/10.1007/s00213-018-4985-6openalex-snapshot
A review of the influence of functional group modifications to the core scaffold of synthetic cathinones on drug pharmacokinetics
inferred← citeshttps://doi.org/10.1007/s00214-022-02940-3openalex-snapshot
New Au(III)- and Fe(III)-based complexes of bio-pharmacological interest: DFT and in silico studies
inferred← citeshttps://doi.org/10.1007/s00234-018-2038-9openalex-snapshot
Is deep brain involvement in intracranial primary central nervous system lymphoma of importance for penetration of chemotherapeutic agents?
inferred← citeshttps://doi.org/10.1007/s00894-022-05266-wopenalex-snapshot
Molecular dynamics simulations of a central nervous system-penetrant drug AZD3759 with lipid bilayer
inferred← citeshttps://doi.org/10.1007/s00894-023-05489-5openalex-snapshot
Threat of respiratory syncytial virus infection knocking the door: a proposed potential drug candidate through molecular dynamics simulations, a future alternative
inferred← citeshttps://doi.org/10.1007/s12035-022-02808-4openalex-snapshot
Cytotoxic and Radiosensitising Effects of a Novel Thioredoxin Reductase Inhibitor in Brain Cancers
inferred← citeshttps://doi.org/10.1007/s12247-025-10349-1openalex-snapshot
Repurposing of FDA-approved Drugs Identifies Glipizide as a Potent HMG-CoA Reductase Inhibitor: a High-Throughput Virtual Screening and Molecular Dynamics Approach for Targeting Hypercholesterolemia
inferred← citeshttps://doi.org/10.1007/s40203-022-00119-zopenalex-snapshot
Modelling and targeting mitochondrial protein tyrosine phosphatase 1: a computational approach
inferred← citeshttps://doi.org/10.1007/s43450-026-00760-1openalex-snapshot
South American Medicinal Plants as Sources of Antiglioblastoma Agents: a Systematic Review of In Vitro Evidence and Cell Death Mechanisms
inferred← citeshttps://doi.org/10.1016/b978-0-12-382030-3.00002-7openalex-snapshot
Lead Discovery and Lead Modification
inferred← citeshttps://doi.org/10.1016/b978-0-12-384976-2.00007-1openalex-snapshot
Pharmacokinetics of 5-Ht6 Receptor Ligands
inferred← citeshttps://doi.org/10.1016/b978-0-12-417150-3.00024-7openalex-snapshot
Glossary of Terms Used in Medicinal Chemistry Part II (IUPAC Recommendations 2013)
inferred← citeshttps://doi.org/10.1016/b978-0-12-417205-0.00027-4openalex-snapshot
Strategies for Enhancing Oral Bioavailability and Brain Penetration
inferred← citeshttps://doi.org/10.1016/b978-0-12-803796-6.00004-6openalex-snapshot
Drug Delivery to the Brain: Pharmacokinetic Concepts
inferred← citeshttps://doi.org/10.1016/b978-0-443-33623-2.00019-2openalex-snapshot
Mechanisms of transport across the blood–brain barrier
inferred← citeshttps://doi.org/10.1016/b978-0-7020-4299-7.00010-xopenalex-snapshot
Metabolism and pharmacokinetic optimization strategies in drug discovery
inferred← citeshttps://doi.org/10.1016/bs.coac.2025.05.002openalex-snapshot
Synthetic cathinones: Pharmacology, toxicological action and analytical approach
inferred← citeshttps://doi.org/10.1016/j.aca.2025.343688openalex-snapshot
Fluorescence imaging of homocysteine dynamics: Complementary diagnostic applications in Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.addr.2025.115621openalex-snapshot
Polypharmacology approaches for brain disorders aimed to enhance brain permeability and circadian clock targeting
inferred← citeshttps://doi.org/10.1016/j.antiviral.2025.106271openalex-snapshot
Structural determinants of nervous system exposure of adibelivir (IM-250) and related herpes helicase-primase inhibitors across animal species
inferred← citeshttps://doi.org/10.1016/j.apsb.2019.08.001openalex-snapshot
Degradation of proteins by PROTACs and other strategies
inferred← citeshttps://doi.org/10.1016/j.bamboo.2025.100157openalex-snapshot
Computational analysis of antimicrobial phytochemicals from Bambusa vulgaris Schrad. ex J.C.Wendl.: Pharmacokinetics, toxicity, and molecular docking
inferred← citeshttps://doi.org/10.1016/j.bbr.2012.08.019openalex-snapshot
Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801
inferred← citeshttps://doi.org/10.1016/j.bbr.2016.01.031openalex-snapshot
The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses
inferred← citeshttps://doi.org/10.1016/j.bcp.2011.12.032openalex-snapshot
Lamotrigine is a substrate for OCT1 in brain endothelial cells
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2022.121581openalex-snapshot
Aggregation-induced emission: An emerging concept in brain science
inferred← citeshttps://doi.org/10.1016/j.bioorg.2016.07.004openalex-snapshot
Synthesis and in vitro evaluation of novel rhodanine derivatives as potential cholinesterase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bioorg.2018.05.019openalex-snapshot
Cytoprotective and antioxidant properties of organic selenides for the myelin-forming cells, oligodendrocytes
inferred← citeshttps://doi.org/10.1016/j.bioorg.2018.07.017openalex-snapshot
Investigation of salicylanilide and 4-chlorophenol-based N-monosubstituted carbamates as potential inhibitors of acetyl- and butyrylcholinesterase
inferred← citeshttps://doi.org/10.1016/j.bioorg.2020.104172openalex-snapshot
Direct inhibition of Keap1-Nrf2 Protein-Protein interaction as a potential therapeutic strategy for Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.105315openalex-snapshot
Synthesis of chalcones derived from 1-naphthylacetophenone and evaluation of their cytotoxic and apoptotic effects in acute leukemia cell lines
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.105472openalex-snapshot
Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.110173openalex-snapshot
Design, synthesis, and biological evaluation of novel selenium-matrine hybrid compounds as topo I -targeted anticancer agents
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.110309openalex-snapshot
Discovery of novel H3R antagonists with potent antiseizure activity and favorable pharmacokinetics via scaffold-hopping from pitolisant to rigid 4-phenylindoles
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.110578openalex-snapshot
Novel pyrimidine-based N-Acylhydrazones as dual AChE inhibitors and antioxidants targeting Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.112549openalex-snapshot
An identification of MARK inhibitors using high throughput MALDI-TOF mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.bmc.2008.07.065openalex-snapshot
Design and synthesis of a metabolically stable and potent antitussive agent, a novel δ opioid receptor antagonist, TRK-851
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.05.005openalex-snapshot
Exploratory analysis of kinetic solubility measurements of a small molecule library
inferred← citeshttps://doi.org/10.1016/j.bmc.2012.07.044openalex-snapshot
Synthesis and evaluation of the anti-proliferative and NF-κB activities of a library of simplified tylophorine analogs
inferred← citeshttps://doi.org/10.1016/j.bmc.2012.11.039openalex-snapshot
Design, synthesis, and evaluation of a water-soluble antofine analogue with high antiproliferative and antitumor activity
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.09.022openalex-snapshot
Antiprion compounds that reduce PrPSc levels in dividing and stationary-phase cells
inferred← citeshttps://doi.org/10.1016/j.bmc.2015.06.022openalex-snapshot
Intriguing possibilities and beneficial aspects of transporter-conscious drug design
inferred← citeshttps://doi.org/10.1016/j.bmc.2016.09.038openalex-snapshot
Sobetirome prodrug esters with enhanced blood–brain barrier permeability
inferred← citeshttps://doi.org/10.1016/j.bmc.2016.09.074openalex-snapshot
Synthesis of N-aryl and N-arylcarbamoylamino derivatives of 1,3-diazinane-5-carboxamide and their activity against glioblastoma LN-229 cell line
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.03.047openalex-snapshot
Ester-to-amide rearrangement of ethanolamine-derived prodrugs of sobetirome with increased blood-brain barrier penetration
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.08.020openalex-snapshot
Anticancer potential of aminomethylidene-diazinanes I. Synthesis of arylaminomethylidene of diazinetriones and its cytotoxic effects tested in glioblastoma cells
inferred← citeshttps://doi.org/10.1016/j.bmc.2018.11.035openalex-snapshot
Design, synthesis, biological evaluation, structure-activity relationship, and toxicity of clinafloxacin-azole conjugates as novel antitubercular agents
inferred← citeshttps://doi.org/10.1016/j.bmc.2019.07.046openalex-snapshot
Novel multitarget 5-arylidenehydantoins with arylpiperazinealkyl fragment: Pharmacological evaluation and investigation of cytotoxicity and metabolic stability
inferred← citeshttps://doi.org/10.1016/j.bmc.2020.115324openalex-snapshot
Design, synthesis and biological evaluation of novel carbamates as potential inhibitors of acetylcholinesterase and butyrylcholinesterase
inferred← citeshttps://doi.org/10.1016/j.bmc.2020.115791openalex-snapshot
The exploration of aza-quinolines as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors with low brain exposure
inferred← citeshttps://doi.org/10.1016/j.bmc.2023.117510openalex-snapshot
Synthesis, anti-inflammatory activity, inverse molecular docking, and acid dissociation constants of new naphthoquinone-thiazole hybrids
inferred← citeshttps://doi.org/10.1016/j.bmc.2025.118536openalex-snapshot
Discovery and in vivo evaluation of a fluorine-18 pro-drug tracer for imaging sphingosine-1-phosphate receptor 2 in the brain
inferred← citeshttps://doi.org/10.1016/j.bmcl.2007.10.078openalex-snapshot
Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: Optimising brain penetration
inferred← citeshttps://doi.org/10.1016/j.bmcl.2008.04.018openalex-snapshot
Non-acidic pyrazole EP1 receptor antagonists with in vivo analgesic efficacy
inferred← citeshttps://doi.org/10.1016/j.bmcl.2008.06.071openalex-snapshot
Derivatives of (3S)-N-(biphenyl-2-ylmethyl)pyrrolidin-3-amine as selective noradrenaline reuptake inhibitors: Reducing P-gp mediated efflux by modulation of H-bond acceptor capacity
inferred← citeshttps://doi.org/10.1016/j.bmcl.2008.08.060openalex-snapshot
Synthesis and activity of 1-(3-amino-1-phenylpropyl)indolin-2-ones: A new class of selective norepinephrine reuptake inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2008.09.103openalex-snapshot
Paclitaxel succinate analogs: Anionic and amide introduction as a strategy to impart blood–brain barrier permeability
inferred← citeshttps://doi.org/10.1016/j.bmcl.2008.10.066openalex-snapshot
Novel 2-imidazoles as potent, selective and CNS penetrant α1A adrenoceptor partial agonists
inferred← citeshttps://doi.org/10.1016/j.bmcl.2009.02.071openalex-snapshot
7-Sulfonamido-3-benzazepines as potent and selective 5-HT2C receptor agonists: Hit-to-lead optimization
inferred← citeshttps://doi.org/10.1016/j.bmcl.2009.03.054openalex-snapshot
3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2009.03.090openalex-snapshot
4-Piperidines and 3-pyrrolidines as dual serotonin and noradrenaline reuptake inhibitors: Design, synthesis and structure–activity relationships
inferred← citeshttps://doi.org/10.1016/j.bmcl.2009.07.063openalex-snapshot
Discovery of a novel azepine series of potent and selective 5-HT2C agonists as potential treatments for urinary incontinence
inferred← citeshttps://doi.org/10.1016/j.bmcl.2009.08.045openalex-snapshot
Using the Golden Triangle to optimize clearance and oral absorption
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.01.137openalex-snapshot
SAR of tertiary carbinamine derived BACE1 inhibitors: Role of aspartate ligand amine pKa in enzyme inhibition
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.01.155openalex-snapshot
Discovery of N-methyl-4-(4-methoxyanilino)quinazolines as potent apoptosis inducers. Structure–activity relationship of the quinazoline ring
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.03.094openalex-snapshot
Discovery of 2-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl)methyl)-5-(5-fluoropyrimidin-2-yl)benzamide as a potent and CNS penetrable P2X7 receptor antagonist
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.08.102openalex-snapshot
Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.09.039openalex-snapshot
5-(Pyridinon-1-yl)indazoles and 5-(furopyridinon-5-yl)indazoles as MCH-1 antagonists
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.09.101openalex-snapshot
Identification of 2-oxo-N-(phenylmethyl)-4-imidazolidinecarboxamide antagonists of the P2X7 receptor
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.11.065openalex-snapshot
Discovery of a series of potent arylthiadiazole H3 antagonists
inferred← citeshttps://doi.org/10.1016/j.bmcl.2010.11.120openalex-snapshot
Pyrimido[4,5-d]azepines as potent and selective 5-HT2C receptor agonists: Design, synthesis, and evaluation of PF-3246799 as a treatment for urinary incontinence
inferred← citeshttps://doi.org/10.1016/j.bmcl.2011.02.086openalex-snapshot
Discovery of pyrrolo[2,3-d]pyrimidin-4-ones as corticotropin-releasing factor 1 receptor antagonists with a carbonyl-based hydrogen bonding acceptor
inferred← citeshttps://doi.org/10.1016/j.bmcl.2011.04.017openalex-snapshot
Quinazolinedione sulfonamides: A novel class of competitive AMPA receptor antagonists with oral activity
inferred← citeshttps://doi.org/10.1016/j.bmcl.2011.05.063openalex-snapshot
Optimisation of a novel series of selective CNS penetrant CB2 agonists
inferred← citeshttps://doi.org/10.1016/j.bmcl.2011.06.078openalex-snapshot
N-Heteroaryl glycinamides and glycinamines as potent NPY5 antagonists
inferred← citeshttps://doi.org/10.1016/j.bmcl.2011.08.048openalex-snapshot
Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 2. Discovery of 7-azaspiro[3.5]nonane urea PF-04862853, an orally efficacious inhibitor of fatty acid amide hydrolase (FAAH) for pain
inferred← citeshttps://doi.org/10.1016/j.bmcl.2011.10.085openalex-snapshot
Quinolinone-based agonists of S1P1: Use of a N-scan SAR strategy to optimize in vitro and in vivo activity
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.02.010openalex-snapshot
An example of designed multiple ligands spanning protein classes: Dual MCH-1R antagonists/DPPIV inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.02.076openalex-snapshot
Fused bicycles as arylketone bioisosteres leading to potent, orally active thiadiazole H3 antagonists
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.04.060openalex-snapshot
Structure guided P1′ modifications of HEA derived β-secretase inhibitors for the treatment of Alzheimer’s disease
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.08.004openalex-snapshot
JD-5006 and JD-5037: Peripherally restricted (PR) cannabinoid-1 receptor blockers related to SLV-319 (Ibipinabant) as metabolic disorder therapeutics devoid of CNS liabilities
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.08.059openalex-snapshot
How hydrogen bonds impact P-glycoprotein transport and permeability
inferred← citeshttps://doi.org/10.1016/j.bmcl.2013.02.082openalex-snapshot
Design and synthesis of 1-aryl-5-anilinoindazoles as c-Jun N-terminal kinase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2013.05.028openalex-snapshot
Hydroxyethylamine-based inhibitors of BACE1: P1–P3 macrocyclization can improve potency, selectivity, and cell activity
inferred← citeshttps://doi.org/10.1016/j.bmcl.2013.06.066openalex-snapshot
Peripherally restricted CB1 receptor blockers
inferred← citeshttps://doi.org/10.1016/j.bmcl.2013.07.044openalex-snapshot
Identification of potent, selective, CNS-targeted inverse agonists of the ghrelin receptor
inferred← citeshttps://doi.org/10.1016/j.bmcl.2013.12.089openalex-snapshot
Identification of potent CNS-penetrant thiazolidinones as novel CGRP receptor antagonists
inferred← citeshttps://doi.org/10.1016/j.bmcl.2013.12.092openalex-snapshot
Discovery of substituted lactams as novel dual orexin receptor antagonists. Synthesis, preliminary structure–activity relationship studies and efforts towards improved metabolic stability and pharmacokinetic properties. Part 1
inferred← citeshttps://doi.org/10.1016/j.bmcl.2014.12.092openalex-snapshot
Development of 2-aminooxazoline 3-azaxanthenes as orally efficacious β-secretase inhibitors for the potential treatment of Alzheimer’s disease
inferred← citeshttps://doi.org/10.1016/j.bmcl.2015.01.023openalex-snapshot
Discovery of novel oxazepine and diazepine carboxamides as two new classes of heat shock protein 90 inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2015.11.050openalex-snapshot
Discovery of the imidazole-derived GPR40 agonist AM-3189
inferred← citeshttps://doi.org/10.1016/j.bmcl.2016.07.032openalex-snapshot
Synthesis and preliminary in vitro kinase inhibition evaluation of new diversely substituted pyrido[3,4-g]quinazoline derivatives
inferred← citeshttps://doi.org/10.1016/j.bmcl.2017.05.072openalex-snapshot
Design and synthesis of novel δ opioid receptor agonists with an azatricyclodecane skeleton for improving blood-brain barrier penetration
inferred← citeshttps://doi.org/10.1016/j.bmcl.2017.07.032openalex-snapshot
Novel 1,2-dihydroquinazolin-2-ones: Design, synthesis, and biological evaluation against Trypanosoma brucei
inferred← citeshttps://doi.org/10.1016/j.bmcl.2018.03.045openalex-snapshot
Discovery of 4-ethoxy-7H-pyrrolo[2,3-d]pyrimidin-2-amines as potent, selective and orally bioavailable LRRK2 inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2019.126772openalex-snapshot
Design, synthesis and evaluation of 2-amino-imidazol-4-one derivatives as potent β-site amyloid precursor protein cleaving enzyme 1 (BACE-1) inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2019.126794openalex-snapshot
Inhibition of hedgehog signaling by stereochemically defined des-triazole itraconazole analogues
inferred← citeshttps://doi.org/10.1016/j.bmcl.2022.128577openalex-snapshot
A kinase inhibitor which specifically targets the ABL myristate pocket (STAMP), but unlike asciminib crosses the blood–brain barrier
inferred← citeshttps://doi.org/10.1016/j.bmcl.2024.129629openalex-snapshot
Discovery and first-time disclosure of CVN766, an exquisitely selective orexin 1 receptor antagonist
inferred← citeshttps://doi.org/10.1016/j.cbi.2019.05.047openalex-snapshot
Assessment of scoring functions and in silico parameters for AChE-ligand interactions as a tool for predicting inhibition potency
inferred← citeshttps://doi.org/10.1016/j.cbpa.2008.02.008openalex-snapshot
Molecular diversity in the context of leadlikeness: compound properties that enable effective biochemical screening
inferred← citeshttps://doi.org/10.1016/j.cbpa.2008.03.019openalex-snapshot
Blood–brain barrier permeability considerations for CNS-targeted compound library design
inferred← citeshttps://doi.org/10.1016/j.cbpa.2010.03.018openalex-snapshot
Current strategies for diversity-oriented synthesis
inferred← citeshttps://doi.org/10.1016/j.compbiolchem.2018.10.015openalex-snapshot
The potential of natural product vs neurodegenerative disorders: In silico study of artoflavanocoumarin as BACE-1 inhibitor
inferred← citeshttps://doi.org/10.1016/j.compbiolchem.2019.107126openalex-snapshot
Integration of core hopping, quantum-mechanics, molecular mechanics coupled binding-energy estimations and dynamic simulations for fragment-based novel therapeutic scaffolds against Helicobacter pylori strains
inferred← citeshttps://doi.org/10.1016/j.drudis.2007.10.005openalex-snapshot
The highly permeable blood–brain barrier: an evaluation of current opinions about brain uptake capacity
inferred← citeshttps://doi.org/10.1016/j.drudis.2022.103366openalex-snapshot
Trends in small molecule drug properties: A developability molecule assessment perspective
inferred← citeshttps://doi.org/10.1016/j.dyepig.2021.109722openalex-snapshot
A photosensitizing perylenediimide dye lights up cell nucleolus through visible light-mediated intracellular translocation
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.03.042openalex-snapshot
Fluorinated benzophenone derivatives: Balanced multipotent agents for Alzheimer's disease
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