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Unexpected Reaction of 2-Alkylsulfanylimidazoles to Imidazol-2-ones: Pyridinylimidazol-2-ones as Novel Potent p38α Mitogen-Activated Protein Kinase Inhibitors
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/j.ab.2005.06.015openalex-snapshot
An immunosorbent, nonradioactive p38 MAP kinase assay comparable to standard radioactive liquid-phase assays
inferredcites →https://doi.org/10.1016/j.bbapap.2005.08.017openalex-snapshot
MAPK signalling pathways as molecular targets for anti-inflammatory therapy—from molecular mechanisms to therapeutic benefits
inferredcites →https://doi.org/10.1021/jm030766kopenalex-snapshot
Novel Substituted Pyridinyl Imidazoles as Potent Anticytokine Agents with Low Activity against Hepatic Cytochrome P450 Enzymes
inferredcites →https://doi.org/10.1021/jm800373topenalex-snapshot
Targeting the Ribose and Phosphate Binding Site of p38 Mitogen-Activated Protein (MAP) Kinase: Synthesis and Biological Testing of 2-Alkylsulfanyl-, 4(5)-Aryl-, 5(4)-Heteroaryl-Substituted Imidazoles
inferredcites →https://doi.org/10.1021/jm801467hopenalex-snapshot
Role of the Hydrogen Bonding Heteroatom−Lys53 Interaction between the p38α Mitogen-Activated Protein (MAP) Kinase and Pyridinyl-Substituted 5-Membered Heterocyclic Ring Inhibitors
inferredcites →https://doi.org/10.1021/jo00253a012openalex-snapshot
Synthetic and mechanistic studies on the preparation of pyridyl-substituted imidazothiazoles
inferredcites →https://doi.org/10.1039/b717605hopenalex-snapshot
Towards the improvement of the synthesis of novel 4(5)-aryl-5(4)-heteroaryl-2-thio-substituted imidazoles and their p38 MAP kinase inhibitory activity
inferredcites →https://doi.org/10.1055/s-2007-1000852openalex-snapshot
Regiospecific and Highly Flexible Synthesis of 1,4,5-Trisubstituted 2-Sulfanylimidazoles from Structurally Diverse Ethanone Precursors
inferredcites →https://doi.org/10.1107/s1600536810009189openalex-snapshot
5-(4-Fluorophenyl)-4-(4-pyridyl)-1,3-oxazol-2-amine
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/ardp.201700258openalex-snapshot
2‐Alkylsulfanyl‐4(5)‐aryl‐5(4)‐heteroarylimidazoles: An Overview on Synthetic Strategies and Biological Activity
inferred← citeshttps://doi.org/10.1002/jhet.2063openalex-snapshot
Selected Methodologies Convenient for the Synthesis of N,5‐Diaryloxazole‐2‐amine Pharmacophore
inferred← citeshttps://doi.org/10.1002/med.21290openalex-snapshot
Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry
inferred← citeshttps://doi.org/10.1016/b978-0-08-102237-5.00004-3openalex-snapshot
Synthesis and Biological Profiles of 4,5-, 1,5-, and 1,2-Diaryl-1 H -imidazoles
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.12460-6openalex-snapshot
Are Two Better Than One in Rheumatoid Arthritis? Development of Dual p38α MAPK/PDE-4 Inhibitors for Treatment of TNFα-Driven Diseases
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114577openalex-snapshot
Hit-to-lead optimization of novel phenyl imidazole carboxamides that are active against Leishmania donovani
inferred← citeshttps://doi.org/10.1016/j.tet.2022.132836openalex-snapshot
Multicomponent synthesis of allomaltol containing 2-aminooxazoles and acid-catalyzed recyclization into substituted furo[3,2-b]pyrans
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.6b01647openalex-snapshot
Discovery of N-{4-[5-(4-Fluorophenyl)-3-methyl-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-acetamide (CBS-3595), a Dual p38α MAPK/PDE-4 Inhibitor with Activity against TNFα-Related Diseases
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.8b00683openalex-snapshot
Discovery of 3-Benzyl-1-( trans -4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors
inferred← citeshttps://doi.org/10.1021/acsomega.8b00668openalex-snapshot
Structural Optimization of a Pyridinylimidazole Scaffold: Shifting the Selectivity from p38α Mitogen-Activated Protein Kinase to c-Jun N-Terminal Kinase 3
inferred← citeshttps://doi.org/10.1039/c5ob01505gopenalex-snapshot
An optimized and versatile synthesis to pyridinylimidazole-type p38α mitogen activated protein kinase inhibitors
inferred← citeshttps://doi.org/10.2174/1573406416666200227122849openalex-snapshot
Current Insights of Inhibitors of p38 Mitogen-Activated Protein Kinase in Inflammation
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