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Insights into Soluble Guanylyl Cyclase Activation Derived from Improved Heme-Mimetics

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jlac.198119810819openalex-snapshot
Aromatische Phosphane mit Substituenten zweiter Ordnung, XVI. Phenyloge PO‐aktivierte Olefinierung: Synthese 4′‐donator‐substituierter 4‐(Diphenylphosphinyl)stilbene
inferredcites →https://doi.org/10.1007/978-3-540-68964-5_13openalex-snapshot
NO-Independent, Haem-Dependent Soluble Guanylate Cyclase Stimulators
inferredcites →https://doi.org/10.1007/978-3-540-68964-5_14openalex-snapshot
NO- and Haem-Independent Soluble Guanylate Cyclase Activators
inferredcites →https://doi.org/10.1007/s10741-009-9149-7openalex-snapshot
Role of guanylate cyclase modulators in decompensated heart failure
inferredcites →https://doi.org/10.1016/j.bmcl.2009.05.033openalex-snapshot
4-(Phenylsulfonamidomethyl)benzamides as potent and selective inhibitors of the 11β-hydroxysteroid dehydrogenase type 1 with efficacy in diabetic ob/ob mice
inferredcites →https://doi.org/10.1016/j.ejmech.2008.04.019openalex-snapshot
Synthesis, characterization and structure–activity relationship analysis of novel depsides as potential antibacterials
inferredcites →https://doi.org/10.1016/j.ejps.2005.09.006openalex-snapshot
Synthesis of novel phenylacetic acid derivatives with halogenated benzyl subunit and evaluation as aldose reductase inhibitors
inferredcites →https://doi.org/10.1016/s0031-6997(24)01457-1openalex-snapshot
Guanylyl Cyclases and Signaling by Cyclic GMP
inferredcites →https://doi.org/10.1016/s0165-6147(97)01137-1openalex-snapshot
Soluble guanylate cyclase: the forgotten sibling
inferredcites →https://doi.org/10.1016/s0165-6147(97)90687-8openalex-snapshot
Soluble guanylate cyclase: the forgotten sibling
inferredcites →https://doi.org/10.1016/s0968-0896(03)00451-6openalex-snapshot
Synthesis of N-benzyl- and N-phenyl-2-amino-4,5-dihydrothiazoles and thioureas and evaluation as modulators of the isoforms of nitric oxide synthase
inferredcites →https://doi.org/10.1021/bi047601dopenalex-snapshot
Expression and Characterization of the Catalytic Domains of Soluble Guanylate Cyclase: Interaction with the Heme Domain
inferredcites →https://doi.org/10.1021/bi301657wopenalex-snapshot
Insights into BAY 60-2770 Activation and S-Nitrosylation-Dependent Desensitization of Soluble Guanylyl Cyclase via Crystal Structures of Homologous Nostoc H-NOX Domain Complexes
inferredcites →https://doi.org/10.1021/jo00975a008openalex-snapshot
Mechanisms of induced decomposition. I. Reactivity of di-tert-butylperoxy homoterephthalate
inferredcites →https://doi.org/10.1021/jo00979a024openalex-snapshot
Palladium-catalyzed vinylic hydrogen substitution reactions with aryl, benzyl, and styryl halides
inferredcites →https://doi.org/10.1021/ol0519487openalex-snapshot
Electrochemically Assisted Heck Reactions
inferredcites →https://doi.org/10.1021/ol8014336openalex-snapshot
Diazonamide Support Studies: Stereoselective Formation of the C10 Chiral Center in both the CDEFG and AEFG Fragments
inferredcites →https://doi.org/10.1038/nrd2038openalex-snapshot
NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential
inferredcites →https://doi.org/10.1074/jbc.m110.111559openalex-snapshot
Structure of Cinaciguat (BAY 58–2667) Bound to Nostoc H-NOX Domain Reveals Insights into Heme-mimetic Activation of the Soluble Guanylyl Cyclase
inferredcites →https://doi.org/10.1074/jbc.m310141200openalex-snapshot
Identification of Residues Crucially Involved in the Binding of the Heme Moiety of Soluble Guanylate Cyclase
inferredcites →https://doi.org/10.1161/01.cir.87.5.1461openalex-snapshot
The nitrovasodilators. New ideas about old drugs.
inferredcites →https://doi.org/10.1161/01.res.0000082524.34487.31openalex-snapshot
Regulation of Nitric Oxide-Sensitive Guanylyl Cyclase
inferredcites →https://doi.org/10.1161/circulationaha.110.981407openalex-snapshot
Nitrate Therapy
inferredcites →https://doi.org/10.1161/circulationaha.110.981738openalex-snapshot
Soluble Guanylate Cyclase as an Emerging Therapeutic Target in Cardiopulmonary Disease
inferredcites →https://doi.org/10.3987/com-88-s146openalex-snapshot
A Facile Route to "Open Chain" Analogues of DDATHF

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4489243openalex-extracted
Synthesis of Purine Conjugates with Bis-Carboranyl Derivatives of (S)-Lysine or (S)-Glutamic Acid
inferred← citeshttps://doi.org/10.1002/ejhf.294openalex-snapshot
Agents with Vasodilator Properties in Acute Heart Failure: How to Design Successful Trials
inferred← citeshttps://doi.org/10.1016/bs.ampbs.2017.01.004openalex-snapshot
Bacterial Haemoprotein Sensors of NO
inferred← citeshttps://doi.org/10.1016/j.bcp.2019.02.007openalex-snapshot
A novel soluble guanylyl cyclase activator, BR 11257, acts as a non-stabilising partial agonist of sGC
inferred← citeshttps://doi.org/10.1016/j.bcp.2025.116739openalex-snapshot
Runcaciguat activates soluble guanylyl cyclase via the histidine essential for heme binding and nitric oxide activation
inferred← citeshttps://doi.org/10.1016/j.bmcl.2021.127886openalex-snapshot
Discovery of CYR715: A novel carboxylic acid-containing soluble guanylate cyclase stimulator
inferred← citeshttps://doi.org/10.1016/j.ejmech.2026.119257openalex-snapshot
Soluble guanylate cyclase stimulators and activators: Chemistry, biology, and therapeutic advances
inferred← citeshttps://doi.org/10.1016/j.ejphar.2020.173203openalex-snapshot
Tyrosine 135 of the β1 subunit as binding site of BAY-543: Importance of the Y-x-S-x-R motif for binding and activation by sGC activator drugs
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.100336openalex-snapshot
Maturation, inactivation, and recovery mechanisms of soluble guanylyl cyclase
inferred← citeshttps://doi.org/10.1016/j.phrs.2016.06.029openalex-snapshot
Regulation of soluble guanylyl cyclase redox state by hydrogen sulfide
inferred← citeshttps://doi.org/10.1016/j.reprotox.2022.08.009openalex-snapshot
Prenatal hypothyroidism diminished exogenous NO-mediated diastolic effects in fetal rat thoracic aorta smooth muscle via increased oxidative stress
inferred← citeshttps://doi.org/10.1021/acs.chemrev.5b00018openalex-snapshot
Gaseous O 2 , NO, and CO in Signal Transduction: Structure and Function Relationships of Heme-Based Gas Sensors and Heme-Redox Sensors
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.8b00007openalex-snapshot
The Discovery of (S)-1-(6-(3-((4-(1-(Cyclopropanecarbonyl)piperidin-4-yl)-2-methylphenyl)amino)-2,3-dihydro-1H-inden-4-yl)pyridin-2-yl)-5-methyl-1H-pyrazole-4-carboxylic Acid, a Soluble Guanylate Cyclase Activator Specifically Designed for Topical Ocular Delivery as a Therapy for Glaucoma
inferred← citeshttps://doi.org/10.1021/acs.oprd.8b00374openalex-snapshot
Iron-Catalyzed Aerobic Oxidation of Alcohols: Lower Cost and Improved Selectivity
inferred← citeshttps://doi.org/10.1038/s41467-021-25617-0openalex-snapshot
Activation mechanism of human soluble guanylate cyclase by stimulators and activators
inferred← citeshttps://doi.org/10.1038/s41598-024-57695-7openalex-snapshot
The efficacy and safety of soluble guanylate cyclase modulation in patients with heart failure: a comprehensive meta-analysis of randomized controlled trials
inferred← citeshttps://doi.org/10.1111/bph.15698openalex-snapshot
Soluble GC stimulators and activators: Past, present and future
inferred← citeshttps://doi.org/10.1124/molpharm.122.000624openalex-snapshot
BAY58-2667 Activates Different Soluble Guanylyl Cyclase Species by Distinct Mechanisms that Indicate Its Principal Target in Cells is the Heme-Free Soluble Guanylyl Cyclase-Heat Shock Protein 90 Complex
inferred← citeshttps://doi.org/10.1186/s12967-022-03800-1openalex-snapshot
Meeting abstracts from the 10th International Conference on cGMP: Generators, Effectors and Therapeutic Implications
inferred← citeshttps://doi.org/10.2174/0929867326666190108095851openalex-snapshot
Therapeutic Targeting of the Soluble Guanylate Cyclase
inferred← citeshttps://doi.org/10.25135/rnp.312.22.01.2314openalex-snapshot
Secondary Metabolites from the Coral-Derived Fungus Aspergillus terreus SCSIO41404 with Pancreatic Lipase Inhibitory Activities
inferred← citeshttps://doi.org/10.3390/molecules28010075openalex-snapshot
Synthesis and In Vitro Comparison of DOTA, NODAGA and 15-5 Macrocycles as Chelators for the 64Cu-Labelling of Immunoconjugates
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