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Design, Synthesis, and Biological Evaluation of Erythrina Alkaloid Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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The Pictet–Spengler Reaction in Nature and in Organic Chemistry
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Beiträge zur Chemie der Carbinolamine. I Untersuchungen an Py‐Tetrahydroisochinolinen
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Synthesis Pathways to Erythrina Alkaloids and Erythrina Type Compounds
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Nicotinic acetylcholine receptors and depression: a review of the preclinical and clinical literature
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An Improved Stereocontrolled Route to cis-Erythrinanes by Combined Intramolecular Strecker and Bruylants Reaction
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Current Place of Monoamine Oxidase Inhibitors in the Treatment of Depression
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Erysodine, a competitive antagonist at neuronal nicotinic acetylcholine receptors
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Nicotine, but not mecamylamine, enhances antidepressant-like effects of citalopram and reboxetine in the mouse forced swim and tail suspension tests
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High-affinity nicotinic acetylcholine receptors are required for antidepressant effects of amitriptyline on behavior and hippocampal cell proliferation
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Aporphine metho salts as neuronal nicotinic acetylcholine receptor blockers
inferredcites →https://doi.org/10.1016/j.bmc.2013.03.024openalex-snapshot
Neonicotinic analogues: Selective antagonists for α4β2 nicotinic acetylcholine receptors
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Structure activity studies of ring E analogues of methyllycaconitine. Part 2: Synthesis of antagonists to the α3β4* nicotinic acetylcholine receptors through modifications to the ester
inferredcites →https://doi.org/10.1016/s0022-3565(24)29396-4openalex-snapshot
Competitive Neuronal Nicotinic Receptor Antagonists: A New Direction for Drug Discovery
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THE ACTION OF SOME DERIVATIVES OF BETA-ERYTHROIDINE ON PERIPHERAL NEURO-EFFECTOR SYSTEMS
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Ion Channel Mutations in Neuronal Diseases: A Genetics Perspective
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Ligand-Gated Ion Channels: New Insights into Neurological Disorders and Ligand Recognition
inferredcites →https://doi.org/10.1021/ja01643a093openalex-snapshot
The Alkaloids—Chemistry and Physiology
inferredcites →https://doi.org/10.1021/jm00163a025openalex-snapshot
Inhibition of monoamine oxidases A and B by simple isoquinoline alkaloids: racemic and optically active 1,2,3,4-tetrahydro-, 3,4-dihydro-, and fully aromatic isoquinolines
inferredcites →https://doi.org/10.1021/jm040219eopenalex-snapshot
Neuronal Nicotinic Acetylcholine Receptors: Structural Revelations, Target Identifications, and Therapeutic Inspirations
inferredcites →https://doi.org/10.1021/jm050069nopenalex-snapshot
Varenicline: An α4β2 Nicotinic Receptor Partial Agonist for Smoking Cessation
inferredcites →https://doi.org/10.1021/jm200834xopenalex-snapshot
Deconstruction of the α4β2 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator Desformylflustrabromine
inferredcites →https://doi.org/10.1021/jm701625vopenalex-snapshot
Novel Acetylcholine and Carbamoylcholine Analogues: Development of a Functionally Selective α4β2Nicotinic Acetylcholine Receptor Agonist
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A photochemical route for erythrane ring construction
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Synthesis and Dopamine Receptor Selectivity of the Benzyltetrahydroisoquinoline, (R)-(+)-nor-Roefractine
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Total Syntheses of (±)-β-Erythroidine and (±)-8-oxo-β-Erythroidine by an Intramolecular Diels−Alder Cycloaddition of a 2-Amidoacrolein
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Using the rat forced swim test to assess antidepressant-like activity in rodents
inferredcites →https://doi.org/10.1038/sj.bjp.0705359openalex-snapshot
Nicotine and nicotinic receptor antagonists potentiate the antidepressant‐like effects of imipramine and citalopram
inferredcites →https://doi.org/10.1039/b710456aopenalex-snapshot
A template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (±)-crispine A
inferredcites →https://doi.org/10.1039/b900189aopenalex-snapshot
New approaches for the synthesis of erythrinan alkaloids
inferredcites →https://doi.org/10.1039/b903035mopenalex-snapshot
Recent advances in the understanding of the interaction of antidepressant drugs with serotonin and norepinephrine transporters
inferredcites →https://doi.org/10.1039/c2cc32442copenalex-snapshot
Covalent attachment of antagonists to the α7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides
inferredcites →https://doi.org/10.1055/s-2008-1032091openalex-snapshot
Highly Efficient Domino Reaction for the Synthesis of the Erythrina and B-Homoerythrina Alkaloid Skeleton
inferredcites →https://doi.org/10.1074/jbc.m109.071183openalex-snapshot
A Synthetic Combinatorial Strategy for Developing α-Conotoxin Analogs as Potent α7 Nicotinic Acetylcholine Receptor Antagonists
inferredcites →https://doi.org/10.1074/jbc.m112.342212openalex-snapshot
Interaction of Antidepressants with the Serotonin and Norepinephrine Transporters
inferredcites →https://doi.org/10.1074/jbc.m806136200openalex-snapshot
Rational Design of α-Conotoxin Analogues Targeting α7 Nicotinic Acetylcholine Receptors
inferredcites →https://doi.org/10.1080/00397918408076803openalex-snapshot
A Convenient Synthesis of Simple Tetrahydroisoquinolines
inferredcites →https://doi.org/10.1080/hrp_8.3.99openalex-snapshot
Biological Aspects of the Link between Smoking and Depression
inferredcites →https://doi.org/10.1124/mol.107.042820openalex-snapshot
Positive Allosteric Modulation of the α7 Nicotinic Acetylcholine Receptor: Ligand Interactions with Distinct Binding Sites and Evidence for a Prominent Role of the M2-M3 Segment
inferredcites →https://doi.org/10.1124/mol.110.065490openalex-snapshot
Molecular Determinants for Competitive Inhibition of α4β2 Nicotinic Acetylcholine Receptors
inferredcites →https://doi.org/10.1124/mol.64.4.865openalex-snapshot
Carbamoylcholine Homologs: Novel and Potent Agonists at Neuronal Nicotinic Acetylcholine Receptors
inferredcites →https://doi.org/10.1124/pr.108.000869openalex-snapshot
SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation
inferredcites →https://doi.org/10.1177/0269881108091587openalex-snapshot
Antidepressant-like effects of nicotinic acetylcholine receptor antagonists, but not agonists, in the mouse forced swim and mouse tail suspension tests
inferredcites →https://doi.org/10.1177/0269881110364271openalex-snapshot
Subtype-selective nicotinic acetylcholine receptor agonists enhance the responsiveness to citalopram and reboxetine in the mouse forced swim test
inferredcites →https://doi.org/10.1248/cpb.36.1275openalex-snapshot
Selective cleavage of aromatic rings by ozonolysis. I. Application to o-dimethoxybenzene derivatives.
inferredcites →https://doi.org/10.1371/journal.pone.0040757openalex-snapshot
Crystal Structure of Lymnaea stagnalis AChBP Complexed with the Potent nAChR Antagonist DHβE Suggests a Unique Mode of Antagonism
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Total Synthesis of Natural Alkaloids Schwarzinicines A-D
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Photoresponsive Aerobic Cross‐Dehydrogenative Coupling Reaction with Ammonium Iodide Catalyst
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Antidepressant Drug Discovery and Development: Mechanism and Drug Design Based on Small Molecules
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Development of a Divergent Synthetic Route to the Erythrina Alkaloids: Asymmetric Syntheses of 8‐Oxo‐erythrinine, Crystamidine, 8‐Oxo‐erythraline, and Erythraline
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Synthesis of Pyrrolidines by a Csp3‐Csp3/Csp3‐N Transition‐Metal‐Free Domino Reaction of Boronic Acids with γ‐Azido‐N‐Tosylhydrazones
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Development of a Divergent Synthetic Route to the Erythrina Alkaloids: Asymmetric Syntheses of 8‐Oxo‐erythrinine, Crystamidine, 8‐Oxo‐erythraline, and Erythraline
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Synthesis of Pyrrolidines by a Csp3‐Csp3/Csp3‐N Transition‐Metal‐Free Domino Reaction of Boronic Acids with γ‐Azido‐N‐Tosylhydrazones
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Photomediated One‐Pot Multicomponent Cascade Reaction for the Synthesis of N‐Acyl/Sulfonyl‐α‐Phosphonated‐1,2,3,4‐Tetrahydroisoquinoline via Twice Acyl/Sulfonyl Iminium Formation
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Synthesis of Condensed Tetrahydroisoquinoline Class of Alkaloids by Employing TfOH‐Mediated Imide Carbonyl Activation
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Oxidation of Trialkylamines by BrCCl3: Scope, Applications and Mechanistic Aspects
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Metal‐Free Multicomponent Construction of Tetrahydroisoquinoline‐Indole Derivatives via In Situ Generated ortho ‐Quinonoid Intermediate
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Phytochemistry and pharmacology of alkaloids from Papaver spp.: a structure–activity based study
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Nature brings new avenues to the therapy of central nervous system diseases—An overview of possible treatments derived from natural products
inferred← citeshttps://doi.org/10.1007/s13659-020-00235-3openalex-snapshot
Artificial Erythrina Alkaloids from Three Erythrina Plants, E. variegata, E. crista-galli and E. arborescens
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Recent advances in applications of Friedel–Crafts reactions in total synthesis of alkaloids
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Synthesis and biological evaluation of a D-ring-contracted analogue of lamellarin D
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Biomolecular recognition of antagonists by α7 nicotinic acetylcholine receptor: Antagonistic mechanism and structure–activity relationships studies
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An efficient access to tetrahydropyrrolo[2,1-a]isoquinoline derivatives based on phosphoranylidene succinimide
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Small molecule ligands for α9 * and α7 nicotinic receptors: A survey and an update, respectively
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Isoquinolines from Corydalis tomentella from Tibet, China, possess hepatoprotective activities
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Total synthesis of natural alkaloids Schwarzinicines A-D
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The Heterogeneous Kinetic Origins of the Binding Properties of Orthosteric Ligands at Heteromeric Nicotinic Acetylcholine Receptors
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Dual Nicotinic Acetylcholine Receptor α4β2 Antagonists/α7 Agonists: Synthesis, Docking Studies, and Pharmacological Evaluation of Tetrahydroisoquinolines and Tetrahydroisoquinolinium Salts
inferred← citeshttps://doi.org/10.1021/acs.joc.0c01992openalex-snapshot
Construction of the Erythrinane Core Skeleton via Asymmetric Catalytic Cascade Reaction of Tertiary Enamides
inferred← citeshttps://doi.org/10.1021/acs.joc.1c00707openalex-snapshot
Erythrina Alkaloid Analogues as nAChR Antagonists–A Flexible Platform for Leads in Drug Discovery
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Tandem H/D Exchange-SET Reductive Deuteration Strategy for the Synthesis of α,β-Deuterated Amines Using D2O
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Tunable Approach to Diverse Phenethylamines via Reduction of 5-Aryloxazolidines with Triethylsilane
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Spokewise Total Syntheses of Four Erythrina Alkaloids and Telescoped Syntheses of Six Additional Alkaloids
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Isoindolinone Synthesis: Selective Dioxane-Mediated Aerobic Oxidation of Isoindolines
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Lewis-Acid-Catalyzed Dearomative [4π + 2σ] Cycloaddition of Bicyclobutanes with Isoquinolinium Methylides for the Synthesis of Ring-Fused Azabicyclo[3.1.1]heptanes
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Catalytic Asymmetric Inverse-Electron Demand 1,3-Dipolar Cycloaddition of Isoquinolinium Methylides with Enecarbamates by a Chiral N,N′-Dioxide/Ag(I) Complex
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Tying up Nicotine: New Selective Competitive Antagonist of the Neuronal Nicotinic Acetylcholine Receptors
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