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Total Syntheses of Parthenolide and Its Analogues with Macrocyclic Stereocontrol

https://doi.org/10.1021/jm5009456
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Allylation of Carbonyls: Methodology and Stereochemistry
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Total Synthesis of Amphidinolide T4
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Towards the Synthesis of Highly Functionalized Chiral α‐Amino Nitriles by Aminative Cyanation and Their Synthetic Applications
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Synthesis of (2E,6E)‐[10‐3H]farnesol and (2E6E)‐[10‐3H]farnesal for insect dehydrogenase studies
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Sesquiterpene lactones from Michelia champaca
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Acid cyclization of 5-ketogermacren-6,12-olides. A reactivity and conformational study
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Indium mediated intramolecular carbocyclization in aqueous media. A facile and stereoselective synthesis of fused α-methylene-γ-butyrolactones
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Purification of Laboratory Chemicals
inferredcites →https://doi.org/10.1016/j.bmc.2010.12.045openalex-snapshot
Melampomagnolide B: A new antileukemic sesquiterpene
inferredcites →https://doi.org/10.1016/j.cbi.2004.07.005openalex-snapshot
Microtubule-interfering activity of parthenolide
inferredcites →https://doi.org/10.1016/j.drudis.2009.08.008openalex-snapshot
New agents for the treatment of leukemia: discovery of DMAPT (LC-1)
inferredcites →https://doi.org/10.1016/j.drudis.2013.05.005openalex-snapshot
Parthenolide: from plant shoots to cancer roots
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Substituent effects in the transannular cyclizations of germacranes. Synthesis of 6-epi-costunolide and five natural steiractinolides
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Chiral 1,4-morpholin-2,5-dione derivatives as α-glucosidase inhibitors: Part 2
inferredcites →https://doi.org/10.1016/s0031-9422(00)00008-xopenalex-snapshot
Fungicidal activity of natural and synthetic sesquiterpene lactone analogs
inferredcites →https://doi.org/10.1016/s0031-9422(99)00141-7openalex-snapshot
Allelochemicals from sunflower leaves cv. Peredovick
inferredcites →https://doi.org/10.1016/s0040-4020(01)87733-4openalex-snapshot
Macroring contraction methodology
inferredcites →https://doi.org/10.1016/s0040-4020(01)93273-9openalex-snapshot
Chemical consequences of conformation in macrocyclic compounds
inferredcites →https://doi.org/10.1016/s0040-4020(99)00025-3openalex-snapshot
The synthesis of germacrane sesquiterpenes and related compounds
inferredcites →https://doi.org/10.1016/s0040-4039(00)61275-3openalex-snapshot
Partial synthesis of germacranolides with pyran and furan-type rings
inferredcites →https://doi.org/10.1016/s0040-4039(97)10750-xopenalex-snapshot
Extremely convenient cyclization of medium rings using SmI2
inferredcites →https://doi.org/10.1016/s0960-894x(99)00529-6openalex-snapshot
Stereoselective synthesis of non symmetric dihydroxyethylene dipeptide isosteres via epoxyalcohols derived from α-amino acids
inferredcites →https://doi.org/10.1016/s0968-0896(02)00553-9openalex-snapshot
Parthenolide and its photochemically synthesized 1(10)Z isomer: chemical reactivity and structure–activity relationship studies in human leucocyte chemotaxis
inferredcites →https://doi.org/10.1016/s1074-5521(01)00049-7openalex-snapshot
The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase
inferredcites →https://doi.org/10.1021/cr00017a002openalex-snapshot
Photochemical one-way adiabatic isomerization of aromatic olefins
inferredcites →https://doi.org/10.1021/ja00036a046openalex-snapshot
Total synthesis of furanocembranolides. 2. Macrocyclization studies culminating in the synthesis of a dihydropseudopterolide and gorgiacerone. Related furanocembranolide interconversions.
inferredcites →https://doi.org/10.1021/ja00037a014openalex-snapshot
Enantioselective complexation of organic ammonium ions by simple tetracyclic podand ionophores
inferredcites →https://doi.org/10.1021/ja00169a065openalex-snapshot
General methodology for the synthesis of neocarzinostatin chromophore analogs: intramolecular chromium-mediated closures for strained ring synthesis
inferredcites →https://doi.org/10.1021/ja00253a032openalex-snapshot
Catalytic asymmetric epoxidation and kinetic resolution: modified procedures including in situ derivatization
inferredcites →https://doi.org/10.1021/ja00316a072openalex-snapshot
Macrocyclic stereocontrol. Total synthesis of (.+-.)-3-deoxyrosaranolide
inferredcites →https://doi.org/10.1021/ja00341a055openalex-snapshot
Synthesis of the cytotoxic germacranolide eucannabinolide
inferredcites →https://doi.org/10.1021/ja00427a062openalex-snapshot
Synthetic methods for sesquiterpene .alpha.-methylene-.gamma.-lactones
inferredcites →https://doi.org/10.1021/ja00538a077openalex-snapshot
The first practical method for asymmetric epoxidation
inferredcites →https://doi.org/10.1021/ja021385jopenalex-snapshot
Enantioselective Total Synthesis of (+)-Amphidinolide T1
inferredcites →https://doi.org/10.1021/ja057434kopenalex-snapshot
Titanium(II)-Mediated Cyclizations of (Silyloxy)enynes: A Total Synthesis of (−)-7-Demethylpiericidin A 1
inferredcites →https://doi.org/10.1021/ja106813sopenalex-snapshot
Simple Reagents for Direct Halonium-Induced Polyene Cyclizations
inferredcites →https://doi.org/10.1021/jf60178a017openalex-snapshot
Sesquiterpenes wth ten-membered carbon rings. Review
inferredcites →https://doi.org/10.1021/jo00063a003openalex-snapshot
A straightforward approach to the synthesis of the tricyclic core of taxol
inferredcites →https://doi.org/10.1021/jo00171a019openalex-snapshot
Acid cyclization and other products of the germacranolide epoxide, lipiferolide
inferredcites →https://doi.org/10.1021/jo00172a070openalex-snapshot
Synthesis of asperdiol
inferredcites →https://doi.org/10.1021/jo00372a047openalex-snapshot
[2,3]-Wittig rearrangement of a 13-membered diallylic ether. Six-step synthesis of costunolide
inferredcites →https://doi.org/10.1021/jo00400a057openalex-snapshot
Preparation of 2-(alkylthiomethyl)acrylates
inferredcites →https://doi.org/10.1021/jo300888sopenalex-snapshot
Biomimetic Semisynthesis of Arglabin from Parthenolide
inferredcites →https://doi.org/10.1021/jo401606qopenalex-snapshot
Protection-Group-Free Semisyntheses of Parthenolide and Its Cyclopropyl Analogue
inferredcites →https://doi.org/10.1021/jo981717wopenalex-snapshot
Competitive Intramolecular/Intermolecular Chelation Options Operative during Indium-Promoted Additions to Pyridyl Aldehydes and to Glyoxylic Acid under Aqueous Conditions
inferredcites →https://doi.org/10.1021/np070252eopenalex-snapshot
Sesquiterpene Lactones from Staehelina fruticosa
inferredcites →https://doi.org/10.1021/np960064gopenalex-snapshot
Antitumor Germacranolides from Anvillea garcinii
inferredcites →https://doi.org/10.1021/np960517hopenalex-snapshot
Structure−Cytotoxicity Relationships of Some Helenanolide-Type Sesquiterpene Lactones
inferredcites →https://doi.org/10.1021/ol036329hopenalex-snapshot
Efficient Medium-Ring Cyclization under Non-High-Dilution Conditions Using SmI2
inferredcites →https://doi.org/10.1021/ol048212eopenalex-snapshot
Alkene Substituents for Selective Activation of endo-Regioselective Polyepoxide Oxacyclizations
inferredcites →https://doi.org/10.1021/ol101030ropenalex-snapshot
γ-Hydroxynitrile Alkylations: Electrophile-Dependent Stereoselectivity
inferredcites →https://doi.org/10.1021/ol201322wopenalex-snapshot
Concise Total Synthesis of (−)-8-Epigrosheimin
inferredcites →https://doi.org/10.1021/ol902984eopenalex-snapshot
Spirodiepoxide Strategy to the C Ring of Pectenotoxin 4: Synthesis of the C1−C19 Sector
inferredcites →https://doi.org/10.1038/442742aopenalex-snapshot
The root of the problem
inferredcites →https://doi.org/10.1039/c39860001405openalex-snapshot
The first biomimetic conversion of a germacrolide-4-epoxide into a xanthanolide
inferredcites →https://doi.org/10.1039/c3np70047jopenalex-snapshot
Natural sesquiterpenoids
inferredcites →https://doi.org/10.1039/np9880500497openalex-snapshot
Natural sesquiterpenoids
inferredcites →https://doi.org/10.1055/s-2006-957833openalex-snapshot
Antiplasmodial Activities and Cytotoxic Effects of Aqueous Extracts and Sesquiterpene Lactones fromNeurolaena lobata*
inferredcites →https://doi.org/10.1097/cmr.0b013e328333bbe4openalex-snapshot
Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro
inferredcites →https://doi.org/10.1128/aac.49.11.176-182.2005openalex-snapshot
Antileishmanial Activity of Parthenolide, a Sesquiterpene Lactone Isolated from Tanacetum parthenium
inferredcites →https://doi.org/10.1158/1078-0432.ccr-09-2937openalex-snapshot
Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells
inferredcites →https://doi.org/10.1182/blood-2004-10-4135openalex-snapshot
The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells
inferredcites →https://doi.org/10.1208/pt0804105openalex-snapshot
The solution and solid state stability and excipient compatibility of parthenolide in feverfew
inferredcites →https://doi.org/10.1248/cpb.38.28openalex-snapshot
Studies on the terpenoids and related alicyclic compounds XXXIX. A synthesis of .ALPHA.-methylene-.GAMMA.-lactones fused to medium and large rings by intramolecular cyclization of formylated allyl halides.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Stereoselective total synthesis of (±)-parthenolide and (±)-7-epi-parthenolide
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Recent advances on the structural modification of parthenolide and its derivatives as anticancer agents
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Enantioselective Total Synthesis of (−)-Vinigrol: The Evolution of a Transannular Diels–Alder Strategy
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Photocatalytic Hantzsch Ester-Mediated Pinacol-Type Coupling of Aldehydes and Ketones
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Synthesis of (±)-4,5-dia-Parthenolide, an Unnatural Parthenolide Stereoisomer
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Visible-Light-Triggered Directly Reductive Arylation of Carbonyl/Iminyl Derivatives through Photocatalytic PCET
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Engineering a Yeast Cell Factory to Sustainably Biosynthesize Parthenolide
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Catalytic enantioselective ene-type reactions of vinylogous hydrazone: construction of α-methylene-γ-butyrolactone derivatives
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Parthenolide and Its Derivatives in the Treatment of Respiratory Tract Diseases: Therapeutic Effects and Molecular Mechanisms
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