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Methods for the Synthesis of 5,6,7,8-Tetrahydro-1,8-naphthyridine Fragments for αVβ3 Integrin Antagonists

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Nonpeptide αvβ3 antagonists. Part 10: In vitro and in vivo evaluation of a potent 7-methyl substituted tetrahydro-[1,8]naphthyridine derivative
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A convenient synthesis of acetylenes: catalytic substitutions of acetylenic hydrogen with bromoalkenes, iodoarenes and bromopyridines
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A highly efficient synthesis of 2-[3-aminopropyl]-5,6,7,8-tetrahydronaphthyridine via a double Suzuki reaction and a Chichibabin cyclization
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Sonogashira cross-coupling reaction of 3-iodoindazoles with various terminal alkynes: a mild and flexible strategy to design 2-aza tryptamines
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Advances in the Chichibabin Reaction
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Phenylbutyrates as potent, orally bioavailable vitronectin receptor (integrin αvβ3) antagonists
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Asymmetric Transfer Hydrogenation of α, β-Acetylenic Ketones
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Nonpeptide αvβ3 Antagonists. 8. In Vitro and in Vivo Evaluation of a Potent αvβ3 Antagonist for the Prevention and Treatment of Osteoporosis
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A convenient palladium-catalyzed coupling approach to 2,5-disubstituted pyridines
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Palladium-catalyzed synthesis of alkynylamino nucleosides. A universal linker for nucleic acids
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Synthesis of the C1‘−C11‘ Oxazole-Containing Side Chain of Leucascandrolide A. Application of a Sonogashira Cross-Coupling
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An Efficient Synthesis of an αvβ3 Antagonist
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Synthesis of the Marine Natural Product Oroidin and Its Z-Isomer
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Polyhalogenated heterocyclic compounds. Part 42.1 Fluorinated nitrogen heterocycles with unusual substitution patterns
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Optimized Procedures for One-Pot Conversion of Alkyl Bromides into Amines via the Staudinger Reaction
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Ligands to the integrin receptor αvβ3

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Molecular Basis of High Enantioselectivity of the Ser47leu Variant of Candida Antarctica Lipase B Towards (R)-But-3-Yn-2-Ol
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A Half Century of the Sonogashira Reaction
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References
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Chichibabin Amination
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Synthesis of Arylated Quinolines by Chemo‐ and Site‐selective Suzuki–Miyaura Reactions of 5,7‐Dibromo‐8‐(trifluoromethanesulfonyloxy)quinoline
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Hydrogen‐Transfer‐Mediated α‐Functionalization of 1,8‐Naphthyridines by a Strategy Overcoming the Over‐Hydrogenation Barrier
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1,8‐Naphthyridine Derivatives: A Review of Multiple Biological Activities
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p‐Phenyleneethynylene Molecular Wires: Influence of Structure on Photoinduced Electron‐Transfer Properties
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Pharmaceuticals
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Attachment at Ring Positions
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Chemo-selective Suzuki–Miyaura reactions: Synthesis of highly substituted [1,6]-naphthyridines
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Synthesis and insecticidal activities of 1,8-naphthyridine derivatives
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Synthesis and conformational behaviors of β-1,2-linked carbopeptoid as a nonionic sugar-hybridized β-peptide
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Three-component one-pot process to propargylic amines and related amide and sulfonamide compounds: application to the construction of 2-(aminomethyl)benzofurans and indoles
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Synthesis of unsymmetrically disubstituted ethynes by the palladium/copper(I)-cocatalyzed sila-Sonogashira–Hagihara coupling reactions of alkynylsilanes with aryl iodides, bromides, and chlorides through a direct activation of a carbon–silicon bond
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Pyridinium N-2′-pyridylaminide: radical cyclization in the synthesis of annulated 2-aminopyridines
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Simple and highly diastereoselective access to 3,4-substituted tetrahydro-1,8-naphthyridines from Morita–Baylis–Hillman adducts
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Microwave assisted synthesis of indolo[2,3-b]dibenzo[b,g][1,8]naphthyridines
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Chemoselective Suzuki-cross coupling reactions of 5-bromoquinolin-8-yl trifluoromethanesulfonate
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Molecular basis for the high enantioselectivity of the Ser47Leu variant of Candida antarctica lipase B toward (R)-But-3-yn-2-ol
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Six-membered ring systems: pyridines and benzo derivatives
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Chapter 4 Pyridines
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The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
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Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
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One-Pot Process for the Amination of Oxazolidinyl-methyl Mesylate by Sodium Diformylamide
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Modular, automated synthesis of spirocyclic tetrahydronaphthyridines from primary alkylamines
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Synthesis of functionalized arylpyridines and -pyrimidines by domino [4+2]/retro [4+2] cycloadditions of electron-rich dienes with alkynylpyridines and -pyrimidines
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Borane-catalyzed metal-free hydrogenation of 2,7-disubstituted 1,8-naphthyridines
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15.1.4 Pyridines (Update 2016)
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Helical folding of β−1,2-linked carbopeptoid induced with organophilic substituents on side groups
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Crystal structure of 2-(4-chlorophenyl)-3-phenyl-1,8-naphthyridine, C20H13N2Cl
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Crystal structure of 2-(naphthalen-2-yl)-1,8-naphthyridine, C18H12N2
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RECENT DEVELOPMENTS AND MULTIPLE BIOLOGICAL ACTIVITIES AVAILABLE WITH 1, 8-NAPHTHYRIDINE DERIVATIVES: A REVIEW
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