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Concise Synthesis of 1,2-Dihydroisoquinolines and 1H-Isochromenes by Carbophilic Lewis Acid-Catalyzed Tandem Nucleophilic Addition and Cyclization of 2-(1-Alkynyl)arylaldimines and 2-(1-Alkynyl)arylaldehydes

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ange.200600408openalex-snapshot

In(OTf)3‐Catalyzed Tandem Nucleophilic Addition and Cyclization of ortho‐Alkynylarylaldimines to 1,2‐Dihydroisoquinolines

inferredcites →https://doi.org/10.1002/anie.200353037openalex-snapshot

Synthesis of Azaphilones and Related Molecules by Employing Cycloisomerization of o‐Alkynylbenzaldehydes

inferredcites →https://doi.org/10.1002/anie.200462280openalex-snapshot

Easy Access to Aryl‐ and Heteroaryl‐Annulated[a]carbazoles by the Indium‐Catalyzed Reaction of 2‐Arylindoles with Propargyl Ethers

inferredcites →https://doi.org/10.1002/anie.200500795openalex-snapshot

Direct Mannich and Nitro‐Mannich Reactions with Non‐Activated Imines: AgOTf‐Catalyzed Addition of Pronucleophiles to ortho‐Alkynylaryl Aldimines Leading to 1,2‐Dihydroisoquinolines

inferredcites →https://doi.org/10.1002/chin.200523079openalex-snapshot

Enantioselective Organocatalytic Hydride Reduction.

inferredcites →https://doi.org/10.1016/j.tet.2005.09.012openalex-snapshot

Domino allylation and cyclization of ortho-alkynylbenzaldehydes with allyltrimethylsilane catalyzed by Pd(II)–Cu(II) bimetallic systems

inferredcites →https://doi.org/10.1016/j.tetlet.2004.08.008openalex-snapshot

Synthesis of 1,2-dihydroisoquinolines via the reaction of ortho-alkynylarylimines with bis-π-allylpalladium

inferredcites →https://doi.org/10.1016/s0040-4039(01)02116-5openalex-snapshot

Three component synthesis of homoallylic amines. Efficient catalysis by lanthanum triflate/benzoic acid

inferredcites →https://doi.org/10.1016/s0040-4039(98)00141-5openalex-snapshot

A facile preparation of benzyltrimethylstannanes and their utility in the synthesis of 1-benzyl-1,2-dihydroisoquinolines

inferredcites →https://doi.org/10.1021/cr010212uopenalex-snapshot

Chemistry and Biology of the Tetrahydroisoquinoline Antitumor Antibiotics

inferredcites →https://doi.org/10.1021/cr950027eopenalex-snapshot

Domino Reactions in Organic Synthesis

inferredcites →https://doi.org/10.1021/ja0010352openalex-snapshot

Asymmetric Reissert-type Reaction Promoted by Bifunctional Catalyst

inferredcites →https://doi.org/10.1021/ja017366bopenalex-snapshot

Pd(II) Acts Simultaneously as a Lewis Acid and as a Transition-Metal Catalyst: Synthesis of Cyclic Alkenyl Ethers from Acetylenic Aldehydes

inferredcites →https://doi.org/10.1021/ja031814topenalex-snapshot

Platinum-Catalyzed Intramolecular Alkylation of Indoles with Unactivated Olefins

inferredcites →https://doi.org/10.1021/ja0355372openalex-snapshot

Cyclization of Carbonyl Groups onto Alkynes upon Reaction with IPy2BF4 and Their Trapping with Nucleophiles: A Versatile Trigger for Assembling Oxygen Heterocycles

inferredcites →https://doi.org/10.1021/ja036927ropenalex-snapshot

Lewis Acid-Catalyzed Benzannulation via Unprecedented [4+2] Cycloaddition of o -Alkynyl(oxo)benzenes and Enynals with Alkynes

inferredcites →https://doi.org/10.1021/ja038006mopenalex-snapshot

Indium-Catalyzed Addition of Active Methylene Compounds to 1-Alkynes

inferredcites →https://doi.org/10.1021/ja043834gopenalex-snapshot

Enantioselective Organocatalytic Hydride Reduction

inferredcites →https://doi.org/10.1021/ja963178nopenalex-snapshot

A New and Practical Synthesis of α-Amino Acids from Alkenyl Boronic Acids

inferredcites →https://doi.org/10.1021/jo00894a601openalex-snapshot

Syntheses of 4-Substituted Isoquinolines

inferredcites →https://doi.org/10.1021/jo010579zopenalex-snapshot

Synthesis of Isoquinolines and Pyridines by the Palladium/Copper-Catalyzed Coupling and Cyclization of Terminal Acetylenes and Unsaturated Imines: The Total Synthesis of Decumbenine B

inferredcites →https://doi.org/10.1021/jo015719jopenalex-snapshot

Diastereoselective Barbier-Type and Palladium-Mediated Allylation of Optically Active Aldimine with Allylindium Reagents

inferredcites →https://doi.org/10.1021/jo026294jopenalex-snapshot

Synthesis of 3,4-Disubstituted Isoquinolines via Palladium-Catalyzed Cross-Coupling of 2-(1-Alkynyl)benzaldimines and Organic Halides

inferredcites →https://doi.org/10.1021/jo035016xopenalex-snapshot

Synthesis of Novel Antitumor Agent 1-Methoxy-5,10- dioxo-5,10-dihydro-1H-benzo[g]isochromene Carboxylic Acid (3-Dimethylylaminopropyl)amide with a Dual Role Pd(II) Catalyst

inferredcites →https://doi.org/10.1021/jo049416bopenalex-snapshot

Synthesis of Cyclic Alkenyl Ethers via Intramolecular Cyclization of O-Alkynylbenzaldehydes. Importance of Combination between CuI Catalyst and DMF

inferredcites →https://doi.org/10.1021/ol036499uopenalex-snapshot

Palladium-Catalyzed Coupling Reaction of Terminal Alkynes with Aryl Iodides in the Presence of Indium Tribromide and Its Application to a One-Pot Synthesis of 2-Phenylindole

inferredcites →https://doi.org/10.1021/ol049690sopenalex-snapshot

Efficient Syntheses of Heterocycles and Carbocycles by Electrophilic Cyclization of Acetylenic Aldehydes and Ketones

inferredcites →https://doi.org/10.1021/ol050069hopenalex-snapshot

A New Entry in Catalytic Alkynylation of Aldehydes and Ketones: Dual Activation of Soft Nucleophiles and Hard Electrophiles by an Indium(III) Catalyst

inferredcites →https://doi.org/10.1021/ol0515917openalex-snapshot

Phosphine Gold(I) Bis-(trifluoromethanesulfonyl)imidate Complexes as New Highly Efficient and Air-Stable Catalysts for the Cycloisomerization of Enynes

inferredcites →https://doi.org/10.1021/ol060645popenalex-snapshot

Water-Triggered and Gold(I)-Catalyzed Cascade Addition/Cyclization of Terminal Alkynes with ortho-Alkynylaryl Aldehyde

inferredcites →https://doi.org/10.1039/b003702hopenalex-snapshot

Friedel–Crafts alkenylation of arenes using alkynes catalysed by metal trifluoromethanesulfonates

inferredcites →https://doi.org/10.1039/b308319eopenalex-snapshot

Indium triflate-catalysed double addition of heterocyclic arenes to alkynes

inferredcites →https://doi.org/10.1039/b513946eopenalex-snapshot

Regioselective indium( iii ) trifluoromethanesulfonate-catalyzed hydrothiolation of non-activated olefins

inferredcites →https://doi.org/10.1055/s-1995-5192openalex-snapshot

Synthetic Organoindium Chemistry: What Makes Indium so Appealing?

inferredcites →https://doi.org/10.1246/cl.1988.913openalex-snapshot

Synthesis and Radical Cyclization of 2-(β-Haloacyl)-1,2-dihydroisoquinolines by Means of Tin Hydride. One-Pot Synthesis of Benzo[f]indolizidine Systems from Isoquinolines

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Rhenium-Catalyzed Synthetic Method of 1,2-Dihydroisoquinolines and Isoquinolines

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Gold, [1,1,1-Trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamidato-kN](Triphenylphosphine)

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Gold in Homogeneous Catalysis

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Intramolecular CX Bond Formation between CX or XH and Alkynes

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Organogold Chemistry

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Gold in Homogeneous Catalysis

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Recent Advances in Nucleophilic Addition Reactions of Organoboronic Acids and Their Derivatives to Unsaturated CN Functionalities

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NMR Structural Characterization of Oxygen Heterocyclic Compounds

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Access to Functionalized Isoquinoline N‐Oxides via Sequential Electrophilic Cyclization/Cross‐Coupling Reactions

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Efficient Syntheses of (Thio)phosphonylated Isobenzofurans by Tandem Nucleophilic Addition and Regioselective 5‐exo‐dig Addition to Carbon‐Carbon Triple Bond: Cooperative Effect to 1,8‐Diazabicyclo[5.4.0]undec‐7‐ene (DBU)

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A Dramatic Substituent Effect in Silver(I)‐Catalyzed Regioselective Cyclization of ortho‐Alkynylaryl Aldehyde Oxime Derivatives

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A General Method for the Synthesis of 5H‐Benzo[b]‐, Carbazolo[2,3‐b]‐ and Indolo[2,3‐b]carbazole Derivatives via Copper(II) Triflate‐Catalyzed Heteroannulation

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Study on the Reactions of Acetylenic Aldehydes with Dimethyl Phosphite in Basic Media: Phosphonate‐Phosphate Rearrangement versus 5‐exo‐dig Cyclization Reactions

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Tunable Dimerization and Trimerization of β‐Alkynyl Ketones via Silver Catalysis for Accessing Spiro and Dispiro Compounds Containing 1H‐Isochromene

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Iron(III) Chloride/Dialkyl Diselenides‐Promoted Cascade Cyclization of ortho‐Diynyl Benzyl Chalcogenides

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2‐Alkynylbenzaldehyde: A Versatile Building Block for the Generation of Cyclic Compounds

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Facile Synthesis of 4‐(Trifluoromethyl)‐1 H‐isochromenes from Alkynols

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Kupfer(I)‐vermittelte oxidative Kreuzkupplung funktionalisierter Alkinyllithiumverbindungen mit Arylmagnesiumreagentien

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PtII‐Catalyzed Synthesis of 9‐Oxabicyclo[3.3.1]nona‐2,6‐dienes from 2‐Alkynyl‐1‐carbonylbenzenes and Allylsilanes by an Allylation/Annulation Cascade

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Synthesis of 3,4‐Dihydroisoquinolines by a C(sp3)H Activation/Electrocyclization Strategy: Total Synthesis of Coralydine

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Concise One‐Pot Tandem Synthesis of Indoles and Isoquinolines from Amides

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One‐Pot Synthesis of Isoquinolinium Salts by Rhodium‐Catalyzed CH Bond Activation: Application to the Total Synthesis of Oxychelerythrine

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Enantioselective Alkynylbenzaldehyde Cyclizations Catalyzed by Chiral Gold(I) Acyclic Diaminocarbene Complexes Containing Weak Au–Arene Interactions

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Chiral Silver Phosphate Catalyzed Transformation of ortho‐Alkynylaryl Ketones into 1H‐Isochromene Derivatives through an Intramolecular‐Cyclization/Enantioselective‐Reduction Sequence

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Ruthenium(0)‐Catalyzed [4+2] Cycloaddition of Acetylenic Aldehydes with α‐Ketols: Convergent Construction of Angucycline Ring Systems

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C,O‐Chelated BINOL/Gold(III) Complexes: Synthesis and Catalysis with Tunable Product Profiles

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Copper(I)‐Mediated Oxidative Cross‐Coupling between Functionalized Alkynyl Lithium and Aryl Magnesium Reagents

inferred← citeshttps://doi.org/10.1002/anie.200800826openalex-snapshot

PtII‐Catalyzed Synthesis of 9‐Oxabicyclo[3.3.1]nona‐2,6‐dienes from 2‐Alkynyl‐1‐carbonylbenzenes and Allylsilanes by an Allylation/Annulation Cascade

inferred← citeshttps://doi.org/10.1002/anie.200804444openalex-snapshot

Synthesis of 3,4‐Dihydroisoquinolines by a C(sp3)H Activation/Electrocyclization Strategy: Total Synthesis of Coralydine

inferred← citeshttps://doi.org/10.1002/anie.200904960openalex-snapshot

Concise One‐Pot Tandem Synthesis of Indoles and Isoquinolines from Amides

inferred← citeshttps://doi.org/10.1002/anie.201105755openalex-snapshot

One‐Pot Synthesis of Isoquinolinium Salts by Rhodium‐Catalyzed CH Bond Activation: Application to the Total Synthesis of Oxychelerythrine

inferred← citeshttps://doi.org/10.1002/anie.201107789openalex-snapshot

Enantioselective Alkynylbenzaldehyde Cyclizations Catalyzed by Chiral Gold(I) Acyclic Diaminocarbene Complexes Containing Weak Au–Arene Interactions

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Chiral Silver Phosphate Catalyzed Transformation of ortho‐Alkynylaryl Ketones into 1H‐Isochromene Derivatives through an Intramolecular‐Cyclization/Enantioselective‐Reduction Sequence

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Ruthenium(0)‐Catalyzed [4+2] Cycloaddition of Acetylenic Aldehydes with α‐Ketols: Convergent Construction of Angucycline Ring Systems

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C,O‐Chelated BINOL/Gold(III) Complexes: Synthesis and Catalysis with Tunable Product Profiles

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Intermolecular Dehydrative Coupling and Intramolecular Cyclization of Ruthenium Vinylidene Complexes Formed from Aromatic Propynes Containing Carbonyl Functionalities

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Isoquinolinium Salts from o‐Halobenzaldehydes, Amines, and Alkynes Catalyzed by Nickel Complexes: Synthesis and Applications

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Access to 1,2‐Dihydroisoquinolines through Gold‐Catalyzed Formal [4+2] Cycloaddition

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Rhodium(II)‐Catalyzed and Thermally Induced Intramolecular Migration of N‐Sulfonyl‐1,2,3‐triazoles: New Approaches to 1,2‐Dihydroisoquinolines and 1‐Indanones

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Nitrogenated Azaphilone Derivatives through a Silver‐Catalysed Reaction of Imines from ortho‐Alkynylbenzaldehydes

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Brønsted Base‐Catalyzed Umpolung Intramolecular Cyclization of Alkynyl Imines

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Urea‐Promoted Neat Synthesis of Fused Dihydroisoquinolines and Disubstituted Pyridines: A Mechanistic Observation with Molecular‐Sensing Studies

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Strategies for the Development of Asymmetric and Non‐Directed Petasis Reactions

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Gold‐Catalyzed Access to Pyrrolo‐ and (Aryl)Indolo‐Fused Phenazines

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Concise Synthesis of 1,2‐Dihydroisoquinolines and 1H‐Isochromenes by Carbophilic Lewis Acid‐Catalyzed Tandem Nucleophilic Addition and Cyclization of 2‐(1‐Alkynyl)arylaldimines and 2‐(1‐Alkynyl)arylaldehydes.

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Microwave‐Promoted Synthesis of N‐Heterocycles by Tandem Imination/Annulation of γ‐ and δ‐Ketoalkynes in the Presence of Ammonia

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Facile Assembly of Fused Isoquinolines by Gold(I)‐Catalyzed Coupling–Cyclization Reactions between o‐Alkynylbenzaldehydes and Aromatic Amines Containing Tethered Nucleophiles

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An Indenone Synthesis Involving a New Aminotransfer Reaction and Its Application to Dibenzopentalene Synthesis

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Enantioselective Allylation of Selected ortho‐Substituted Benzaldehydes: A Comparative Study

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Introduction

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Facile Synthesis of 3-(Aminomethyl)isoquinoline by Copper-Catalyzed Domino Four-Component Coupling and Cyclization

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Rapid Access to 3-(Aminomethyl)isoquinoline-Fused Polycyclic Compounds by Copper-Catalyzed Four Component Coupling, Cascade Cyclization, and Oxidation

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Gold-catalyzed C–O bond forming reactions for the synthesis of six-membered O-heterocycles

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Gallium and Indium Complexes in Organic Synthesis

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Six-membered fused N-heterocycles

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Six-membered O-polyheterocycles

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Transition-metal-catalyzed reactions of aldehyde-yne derivatives: An original and efficient access to heterocycles

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Gold-catalyzed stereoselective reaction of tricarbonylchromium complexes of ortho-alkynyl benzaldehydes and benzaldimines with nucleophiles

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Tandem imination/annulation of γ- and δ-ketoalkynes in the presence of ammonia/amines

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Design and synthesis of two triazonine-carbaldehyde derivatives using several chemical tools

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Synthesis of 6-(arylmethylidene)octahydropyrrolo[1,2-a]pyrimidines and 5-(arylmethylidene)hexahydropyrrolo[1,2-a]imidazoles by the interaction of alk-4-ynals with a,?-diaminoalkanes in DMSO in the presence of KOH

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New selective cyclizations of alk-4-ynals with primary amines and azoles:one-pot synthesis of 2-azolylpyrrolidines and 3-iminocyclopentenes

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One-pot sonochemical synthesis and in silico/in vitro antitubercular evaluation of 1-methyl-3-propyl-1H-pyrazole containing polynuclear fused N-heteroarenes

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An efficient route to 2,3-disubstituted-1,2-dihydroisoquinolin-1-ylphosphonates via CuI-catalyzed three-component reactions

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Three-component reaction of 2-alkynylbenzaldehyde, amine, and nucleophile using Lewis acid-surfactant combined catalyst in water

inferred← citeshttps://doi.org/10.1016/j.tet.2007.11.092openalex-snapshot

Synthesis of six-membered oxygenated heterocycles through carbon–oxygen bond-forming reactions

inferred← citeshttps://doi.org/10.1016/j.tet.2008.12.038openalex-snapshot

Synthesis of 1,2-dihydroisoquinolin-1-ylphosphonates via three-component reactions of 2-(2-formylphenyl)ethanone, amine, and diethyl phosphite

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Highly efficient synthesis of functionalized dihydronaphthalenes, tetrahydronaphthalenes, and tetrahydroisoquinolines by iron-catalyzed intramolecular Friedel–Crafts reaction of aryl-containing propargylic alcohols

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Library construction of 1-(1H-imidazol-1-yl)-1,2-dihydroisoquinolines via three-component reaction of 2-alkynylbenzaldehyde, amine, and imidazole

inferred← citeshttps://doi.org/10.1016/j.tet.2012.02.058openalex-snapshot

Chiral counteranion-directed silver-catalyzed asymmetric synthesis of 1,2-dihydroisoquinolines by Friedel–Crafts alkylation reactions

inferred← citeshttps://doi.org/10.1016/j.tet.2012.12.065openalex-snapshot

Synthesis of C(27)–C(38) fragment of aflastatin A

inferred← citeshttps://doi.org/10.1016/j.tet.2012.12.068openalex-snapshot

An economical nucleophilic route toward facile synthesis of pyrano[4,3-b]quinolin-1-ones via 6-endo-dig cyclization of o-alkynylquinoline esters

inferred← citeshttps://doi.org/10.1016/j.tet.2014.02.026openalex-snapshot

Facile assembly of 1-(4-haloisoquinolin-1-yl)ureas via a reaction of 2-alkynylbenzaldoxime, carbodiimide, and halide in water

inferred← citeshttps://doi.org/10.1016/j.tet.2014.04.072openalex-snapshot

One-pot synthesis of trifluoromethylated phthalans via intramolecular cyclization from 2-alkynylbenzaldehydes

inferred← citeshttps://doi.org/10.1016/j.tet.2017.07.051openalex-snapshot

Silver-catalyzed tandem nucleophilic addition/cycloisomerization of ortho-alkynylbenzaldehydes: Regioselective synthesis of functionalized 1H-isochromene derivatives

inferred← citeshttps://doi.org/10.1016/j.tet.2018.05.063openalex-snapshot

Isoquinoline synthesis by C-H activation/annulation using vinyl acetate as an acetylene equivalent

inferred← citeshttps://doi.org/10.1016/j.tet.2024.133854openalex-snapshot

Rhenium-catalyzed synthetic method of 1,2-dihydroisoquinolines and isoquinolines by the intramolecular cyclization of 2-alkynylaldimines or 2-alkynylbenzylamines

inferred← citeshttps://doi.org/10.1016/j.tetlet.2008.02.143openalex-snapshot

AgOTf-catalyzed one-pot reaction of 2-alkynylbenzaldehyde, amine, and sodium borohydride

inferred← citeshttps://doi.org/10.1016/j.tetlet.2008.05.009openalex-snapshot

Synthesis of 1H-isochromen-1-ylphosphonates via AgOTf-catalyzed reaction of 2-alkynylbenzaldehyde with diethyl phosphite

inferred← citeshttps://doi.org/10.1016/j.tetlet.2008.10.121openalex-snapshot

Tandem cyclization-[3+3] cycloaddition reactions of 2-alkynylbenzaldoxime: synthesis of fused 1,2-dihydroisoquinolines

inferred← citeshttps://doi.org/10.1016/j.tetlet.2009.02.144openalex-snapshot

AgOTf and TfOH co-catalyzed isoquinoline synthesis via redox reactions of O-alkyl oximes

inferred← citeshttps://doi.org/10.1016/j.tetlet.2009.03.159openalex-snapshot

Synthesis of polysubstituted 1,2-dihydroisoquinolines via a CuI-catalyzed arylation/condensation cascade process

inferred← citeshttps://doi.org/10.1016/j.tetlet.2009.03.168openalex-snapshot

Aza Hopf cyclization: synthesis and reactivity of cyclic azadieneynes

inferred← citeshttps://doi.org/10.1016/j.tetlet.2009.04.126openalex-snapshot

One-pot concise syntheses of benzimidazo[2,1-a]isoquinolines by a microwave-accelerated tandem process

inferred← citeshttps://doi.org/10.1016/j.tetlet.2009.05.013openalex-snapshot

Lewis acid-catalyzed reactions of N′-(2-alkynylbenzylidene)hydrazides with diethyl phosphite

inferred← citeshttps://doi.org/10.1016/j.tetlet.2009.05.106openalex-snapshot

Multicatalytic synthesis of 1,2-dihydroisoquinolin-1-ylphosphonates via a tandem four-component reaction

inferred← citeshttps://doi.org/10.1016/j.tetlet.2009.09.005openalex-snapshot

Silver triflate and triphenylphosphine co-catalyzed reactions of 2-alkynylbenzaldehyde, amine, and α,β-unsaturated ketone

inferred← citeshttps://doi.org/10.1016/j.tetlet.2009.09.095openalex-snapshot

Pybox ligand-promoted copper(I)-catalyzed three-component tandem coupling-annulation of terminal alkynes, amines and ortho-alkynylaryl aldehydes

inferred← citeshttps://doi.org/10.1016/j.tetlet.2009.12.052openalex-snapshot

Gold(I)-catalyzed stereoselective cyclization of ortho alkynyl benzaldehyde chromium complexes with nucleophiles

inferred← citeshttps://doi.org/10.1016/j.tetlet.2012.09.033openalex-snapshot

Efficient synthesis of novel tetrahydropyrrolo[3′,4′:3,4]pyrrolo[2,1-a] isoquinoline derivatives via a simple and convenient MCR in aqueous micellar system

inferred← citeshttps://doi.org/10.1016/j.tetlet.2014.08.076openalex-snapshot

Cu(OTf)2-promoted efficient synthetic route towards glycospiro-pyrrolo[2,1-a]isoquinolines

inferred← citeshttps://doi.org/10.1016/s0959-6380(09)70019-4openalex-snapshot

Chapter 6.4 (2006): Six-membered ring systems: with O and/or S atoms

inferred← citeshttps://doi.org/10.1016/s0959-6380(09)70020-0openalex-snapshot

Chapter 6.4 (2007): Six-membered ring systems: with O and/or S atoms

inferred← citeshttps://doi.org/10.1021/acs.chemrev.6b00203openalex-snapshot

Fluorine and Gold: A Fruitful Partnership

inferred← citeshttps://doi.org/10.1021/acs.joc.3c00261openalex-snapshot

Intramolecular 7- endo - dig -Selective Carbosilylation of Internal Alkynes Involving Silylium-Ion Regeneration

inferred← citeshttps://doi.org/10.1021/acs.joc.4c02239openalex-snapshot

Copper-Catalyzed Domino Phosphorylation/Cyclization of ortho -Alkynylketones for Accessing Phosphorylated 1 H -Isochromenes

inferred← citeshttps://doi.org/10.1021/acs.joc.6b00565openalex-snapshot

Organocatalytic Enantioselective Intramolecular Oxa-Michael Reaction of Enols: Synthesis of Chiral Isochromenes

inferred← citeshttps://doi.org/10.1021/acs.joc.8b01921openalex-snapshot

Selective Divergent Synthesis of Indanols, Indanones, and Indenes via Acid-Mediated Cyclization of (Z)- and (E)-(2-Stilbenyl)methanols and Its Application for the Synthesis of Paucifloral F Derivatives

inferred← citeshttps://doi.org/10.1021/acs.joc.8b03081openalex-snapshot

Unusual Reactivity of Isoquinolinones Generated by Silver-Catalyzed Cycloisomerizations of Imines Derived from ortho-Alkynylsalicylaldehydes

inferred← citeshttps://doi.org/10.1021/acs.joc.9b00662openalex-snapshot

Cu(I)-Catalyzed Oxygen and Nitrogen Nucleophiles Triggered Regioselective Synthesis of Furo/Pyrrolo-Annulated Quinolines

inferred← citeshttps://doi.org/10.1021/acs.organomet.6b00146openalex-snapshot

Triaryl-Like MONO-, BIS-, and TRISKITPHOS Phosphines: Synthesis, Solution NMR Studies, and a Comparison in Gold-Catalyzed Carbon–Heteroatom Bond Forming 5-exo-dig and 6-endo-dig Cyclizations

inferred← citeshttps://doi.org/10.1021/acs.orglett.1c01220openalex-snapshot

Aromaticity-Driven Access to Cycloalkyl-Fused Naphthalenes

inferred← citeshttps://doi.org/10.1021/acs.orglett.1c01518openalex-snapshot

Asymmetric Synthesis of 3-Methyleneindolines via Rhodium(I)-Catalyzed Alkynylative Cyclization of N-(o-Alkynylaryl)imines

inferred← citeshttps://doi.org/10.1021/acs.orglett.5b02159openalex-snapshot

Ag(I)-Catalyzed Three-Component Reaction of 2-Alkynylbenzaldehydes, Amines, and Diazo Compounds

inferred← citeshttps://doi.org/10.1021/acs.orglett.5b03146openalex-snapshot

Synthesis of Functionalized 1H-Isochromene Derivatives via a Au-Catalyzed Domino Cycloisomerization/Reduction Approach

inferred← citeshttps://doi.org/10.1021/acs.orglett.6c00112openalex-snapshot

Palladium-Catalyzed Enantioselective Tandem Allylation/Cyclization of ortho -Alkynylbenzaldehydes with Allyltrimethylsilane: Access to Chiral 1-Allyl-1 H -isochromenes

inferred← citeshttps://doi.org/10.1021/acs.orglett.8b00330openalex-snapshot

Dehydrative Mannich-Type Reaction for the Synthesis of Azepinobisindole Alkaloid Iheyamine A

inferred← citeshttps://doi.org/10.1021/acs.orglett.9b02010openalex-snapshot

Carbon Tetrachloride-Mediated Cyclization of (2-Alkynyl)arylaldimines for the Synthesis of Polychlorinated Nitrogen Heterocycles

inferred← citeshttps://doi.org/10.1021/acscatal.6b02636openalex-snapshot

Gold-Catalyzed Access to 1H-Isochromenes: Reaction Development and Mechanistic Insight

inferred← citeshttps://doi.org/10.1021/cc1000314openalex-snapshot

Tandem Reactions of N′-(2-Alkynylbenzylidene)hydrazides with Silyl Enolates: A Facile Route to H-Pyrazolo[5,1-a]isoquinolines

inferred← citeshttps://doi.org/10.1021/cc9000482openalex-snapshot

Green Method for the Synthesis of Highly Substituted Cyclohexa-1,3-diene, Polyhydroindene, Polyhydronaphthalene, Isochromene, Isothiochromene, and Isoquinoline Derivatives in Ionic Liquids

inferred← citeshttps://doi.org/10.1021/cc9001263openalex-snapshot

Synthesis of 1-(1H-Indol-3-yl)-1,2-dihydroisoquinolines via AgOTf-Catalyzed Three-Component Reactions of 2-Alkynylbenzaldehydes, Amines, and Indoles

inferred← citeshttps://doi.org/10.1021/co1000794openalex-snapshot

Solution-Phase Parallel Synthesis of a Diverse Library of 1,2-Dihydroisoquinolines

inferred← citeshttps://doi.org/10.1021/cr050041jopenalex-snapshot

Coinage Metal-Assisted Synthesis of Heterocycles

inferred← citeshttps://doi.org/10.1021/cr068430gopenalex-snapshot

Ligand Effects in Homogeneous Au Catalysis

inferred← citeshttps://doi.org/10.1021/cr068435dopenalex-snapshot

Alternative Synthetic Methods through New Developments in Catalysis by Gold

inferred← citeshttps://doi.org/10.1021/cr300051yopenalex-snapshot

Organoindium Reagents: The Preparation and Application in Organic Synthesis

inferred← citeshttps://doi.org/10.1021/cr300389uopenalex-snapshot

Late Transition Metal-Catalyzed Hydroamination and Hydroamidation

inferred← citeshttps://doi.org/10.1021/jo101347fopenalex-snapshot

Platinum-Catalyzed, One-Pot Tandem Synthesis of Indoles and Isoquinolines via Sequential Rearrangement of Amides and Aminocyclization

inferred← citeshttps://doi.org/10.1021/jo101905ropenalex-snapshot

Facile Synthesis of Selenium/Sulfur-Substituted 3-Oxa-bicyclo[4.2.0]octa-1(8),5-diene and Tetrahydro-1H-isochromene via Sequential Three-Component Conjugate Addition/Condensation/Elimination/[2 + 2] or [4 + 2] Cyclization Reactions

inferred← citeshttps://doi.org/10.1021/jo201596popenalex-snapshot

Copper(II)-Catalyzed Asymmetric Henry Reaction of o-Alkynylbenzaldehydes Followed by Gold(I)-Mediated Cycloisomerization: An Enantioselective Route to Chiral 1H-Isochromenes and 1,3-Dihydroisobenzofurans

inferred← citeshttps://doi.org/10.1021/jo300251copenalex-snapshot

Multisubstituted Furan Formation from (Z)- or (E)-Enynyl Acetates: Tandem Reactions Accelerated by Electron-Donating Groups on Aromatic Rings

inferred← citeshttps://doi.org/10.1021/jo3021055openalex-snapshot

Synthesis of Tetrasubstituted Cyclopentadienes via Palladium-Catalyzed Reaction of (Z)-2-En-4-yn Acetates and N-Methyl Indoles

inferred← citeshttps://doi.org/10.1021/jo4009639openalex-snapshot

On Water: Silver-Catalyzed Domino Approach for the Synthesis of Benzoxazine/Oxazine-Fused Isoquinolines and Naphthyridines from o-Alkynyl Aldehydes

inferred← citeshttps://doi.org/10.1021/jo401929qopenalex-snapshot

Synthesis of Triazolo Isoquinolines and Isochromenes from 2-Alkynylbenzaldehyde via Domino Reactions under Transition-Metal-Free Conditions

inferred← citeshttps://doi.org/10.1021/jo5002559openalex-snapshot

Mild Regiospecific Synthesis of 1-Alkoxy-isochromenes Catalyzed by Well-Defined [Silver(I)(Pyridine-Containing Ligand)] Complexes

inferred← citeshttps://doi.org/10.1021/jo7016839openalex-snapshot

Synthesis of Functionalized 1,2-Dihydroisoquinolines via Multicomponent One-Pot Reaction of 2-Alkynylbenzaldehyde, Amine, Zinc, and Allylic Bromide or Benzyl Bromide

inferred← citeshttps://doi.org/10.1021/jo702342ropenalex-snapshot

One-Step Synthesis of Substituted Dihydro- and Tetrahydroisoquinolines by FeCl3·6H2O Catalyzed Intramolecular Friedel−Crafts Reaction of Benzylamino-Substituted Propargylic Alcohols

inferred← citeshttps://doi.org/10.1021/jo800464uopenalex-snapshot

InBr3-Promoted Divergent Approach to Polysubstituted Indoles and Quinolines from 2-Ethynylanilines: Switch from an Intramolecular Cyclization to an Intermolecular Dimerization by a Type of Terminal Substituent Group

inferred← citeshttps://doi.org/10.1021/jo800474copenalex-snapshot

Indium(III)-Catalyzed Tandem Reaction with Alkynylbenzaldehydes and Alkynylanilines to Heteroaromatic Compounds

inferred← citeshttps://doi.org/10.1021/jo800898kopenalex-snapshot

Concise Synthesis of the CDE Ring System of Tetrahydroisoquinoline Alkaloids Using Carbophilic Lewis Acid-Catalyzed Hydroamidation and Oxidative Friedel−Crafts Cyclization

inferred← citeshttps://doi.org/10.1021/jo801390xopenalex-snapshot

Computational Analysis on the Dual Reactivity of Conjugated “Ene-Ene-Yne” Systems

inferred← citeshttps://doi.org/10.1021/jo802076kopenalex-snapshot

Tandem Electrophilic Cyclization−[3+2] Cycloaddition−Rearrangement Reactions of 2-Alkynylbenzaldoxime, DMAD, and Br2

inferred← citeshttps://doi.org/10.1021/jo802435bopenalex-snapshot

Tandem β-Enamino Ester Formation and Cyclization with o-Alkynyl Anilines Catalyzed by InBr3: Efficient Synthesis of β-(N-Indolyl)-α,β-unsaturated Esters

inferred← citeshttps://doi.org/10.1021/jo901090uopenalex-snapshot

Rapid Access to 3-(Aminomethyl)isoquinoline-Fused Polycyclic Compounds by Copper-Catalyzed Four-Component Coupling, Cascade Cyclization, and Oxidation

inferred← citeshttps://doi.org/10.1021/jo901906bopenalex-snapshot

Gold(I)-Catalyzed Tandem Reactions Initiated by Hydroamination of Alkynyl Carbamates: Application to the Synthesis of Nitidine

inferred← citeshttps://doi.org/10.1021/jo902333yopenalex-snapshot

A Simple and Mild Synthesis of 1H-Isochromenes and (Z)-1-Alkylidene-1,3-dihydroisobenzofurans by the Iodocyclization of 2-(1-Alkynyl)benzylic Alcohols

inferred← citeshttps://doi.org/10.1021/ol102939ropenalex-snapshot

Synthesis of H-Pyrazolo[5,1-a]isoquinolines via Copper(II)-Catalyzed Oxidation of an Aliphatic C−H Bond of Tertiary Amine in Air

inferred← citeshttps://doi.org/10.1021/ol300901xopenalex-snapshot

An Unexpected Silver Triflate Catalyzed Reaction of 2-Alkynylbenzaldehyde with 2-Isocyanoacetate

inferred← citeshttps://doi.org/10.1021/ol301023mopenalex-snapshot

Silver Triflate and Palladium Acetate Co-catalyzed Reaction of N′-(2-Alkynylbenzylidene)hydrazide with N-Allyl Ynamide

inferred← citeshttps://doi.org/10.1021/ol3035142openalex-snapshot

Gold-Catalyzed Intramolecular Hydroamination of o-Alkynylbenzyl Carbamates: A Route to Chiral Fluorinated Isoindoline and Isoquinoline Derivatives

inferred← citeshttps://doi.org/10.1021/ol402996xopenalex-snapshot

Cu-Catalyzed 1,2-Dihydroisoquinolines Synthesis from o-Ethynyl Benzacetals and Sulfonyl Azides

inferred← citeshttps://doi.org/10.1021/ol501329topenalex-snapshot

Synthesis of Isochromene-Type Scaffolds via Single-Flask Diels–Alder-[4 + 2]-Annulation Sequence of a Silyl-Substituted Diene with Menadione

inferred← citeshttps://doi.org/10.1021/ol5021256openalex-snapshot

Silver-Catalyzed Domino Hydroarylation/Cycloisomerization Reactions of ortho-Alkynylbenzaldehydes: An Entry to Functionalized Isochromene Derivatives

inferred← citeshttps://doi.org/10.1021/ol502938yopenalex-snapshot

Regioselective Asao–Yamamoto Benzannulations of Diaryl Acetylenes

inferred← citeshttps://doi.org/10.1021/ol7020669openalex-snapshot

Lewis Acid- and Organocatalyst-Cocatalyzed Multicomponent Reactions of 2-Alkynylbenzaldehydes, Amines, and Ketones

inferred← citeshttps://doi.org/10.1021/ol7024668openalex-snapshot

Synthesis of Quinoline-2-thiones via Tandem Indium(III)-Promoted Friedel−Crafts Alkenylation−Cyclization of 2-Alkynylphenyl Isothiocyanates

inferred← citeshttps://doi.org/10.1021/ol902409uopenalex-snapshot

Rh2(OAc)4-AgOTf Cooperative Catalysis in Cyclization/Three-Component Reactions for Concise Synthesis of 1,2-Dihydroisoquinolines

inferred← citeshttps://doi.org/10.1039/b718201eopenalex-snapshot

Facile synthesis of 3-(aminomethyl)isoquinolines by copper-catalysed domino four-component coupling and cyclisation

inferred← citeshttps://doi.org/10.1039/b904498aopenalex-snapshot

AgOTf-catalyzed tandem reaction of N′-(2-alkynylbenzylidene)hydrazide with alkyne

inferred← citeshttps://doi.org/10.1039/b908313hopenalex-snapshot

Efficient syntheses of phosphonylated isochromenes by regioselective 6-endo-dig addition to carbon-carbon triple bond catalyzed by Pd(OAc)2

inferred← citeshttps://doi.org/10.1039/c001350aopenalex-snapshot

Silver catalyzed cascade synthesis of alkaloid ring systems: concise total synthesis of fascaplysin, homofascaplysin C and analogues

inferred← citeshttps://doi.org/10.1039/c1gc15346copenalex-snapshot

Highly efficient Ag(i)-catalyzed regioselective tandem synthesis of diversely substituted quinoxalines and benzimidazoles in water

inferred← citeshttps://doi.org/10.1039/c1ob05258fopenalex-snapshot

Synthesis of functionalized ellipticinium and ellipticine derivatives via electrophilic cyclization

inferred← citeshttps://doi.org/10.1039/c1ob06271aopenalex-snapshot

Silver-catalysed intramolecular cyclisation of 2-alkynylacetophenones and 3-acetyl-2-alkynylpyridines in the presence of ammonia

inferred← citeshttps://doi.org/10.1039/c2cc17450bopenalex-snapshot

Tuning the reactivity of Au-complexes in an Au(i)/chiral Brønsted acid cooperative catalytic system: an approach to optically active fused 1,2-dihydroisoquinolines

inferred← citeshttps://doi.org/10.1039/c2cc33426gopenalex-snapshot

A CuBr-mediated aerobic reaction of 2-alkynylbenzaldehydes and primary amines: synthesis of 4-bromoisoquinolones

inferred← citeshttps://doi.org/10.1039/c3ra42730gopenalex-snapshot

Generation of diverse isoquinoline N-oxides in an aqueous system

inferred← citeshttps://doi.org/10.1039/c4ob02036gopenalex-snapshot

An expedient approach to 1,2-dihydroisoquinoline derivatives via cobalt catalysed 6-endo dig cyclization followed by Mannich condensation of o-alkynylarylaldimines

inferred← citeshttps://doi.org/10.1039/c4ra02581dopenalex-snapshot

Microwave assisted [RuCl 2 (p-cymene) 2 ] 2 catalyzed regioselective endo-tandem cyclization involving imine and alkyne activation: an approach to benzo[4,5]imidazo[2,1-a]pyridine scaffold

inferred← citeshttps://doi.org/10.1039/c5ob02405fopenalex-snapshot

One-pot synthesis of 1H-isochromenes and 1,2-dihydroisoquinolines by a sequential isocyanide-based multicomponent/Wittig reaction

inferred← citeshttps://doi.org/10.1039/c5ra24541aopenalex-snapshot

Gold-catalyzed tandem cycloisomerization/Petasis–Ferrier rearrangement: a direct route to 3-alkoxyindanones from enynals and alcohols

inferred← citeshttps://doi.org/10.1039/c6ob01790hopenalex-snapshot

Regioselective synthesis of functionalized dihydroisoquinolines from o-alkynylarylaldimines via the Reformatsky reaction

inferred← citeshttps://doi.org/10.1039/c6ob02133fopenalex-snapshot

BF 3 ·Et 2 O mediated one-step synthesis of N-substituted-1,2-dihydropyridines, indenopyridines and 5,6-dihydroisoquinolines

inferred← citeshttps://doi.org/10.1039/c6qo00203jopenalex-snapshot

Pd catalyzed facile synthesis of cyclopenta[b]quinolin-1-one via sequential Sonogashira coupling and annulation. An unusual mode of ring closure, using sulphur as a soft nucleophile

inferred← citeshttps://doi.org/10.1039/c8ob01426dopenalex-snapshot

Indium( iii ) as π-acid catalyst for the electrophilic activation of carbon–carbon unsaturated systems

inferred← citeshttps://doi.org/10.1039/c8ra09269aopenalex-snapshot

Synthesis of 4-(1 H -isochromen-1-yl)isoquinolines through the silver-catalysed homodimerization of ortho -alkynylarylaldehydes and subsequent condensation of the 1,5-dicarbonyl motif with NH 3

inferred← citeshttps://doi.org/10.1039/d1ob00760bopenalex-snapshot

Synthesis of substituted 1,2-dihydroisoquinolines via Ni( ii ) and Cu( i )/Ag( i ) catalyzed double nucleophilic addition of arylamines to ortho -alkynyl donor–acceptor cyclopropanes ( o -ADACs)

inferred← citeshttps://doi.org/10.1039/d2ob00900eopenalex-snapshot

AgNTf 2 catalyzed cycloaddition of N -acyliminium ions with alkynes for the synthesis of the 3,4-dihydro-1,3-oxazin-2-one skeleton

inferred← citeshttps://doi.org/10.1039/d3qo00134bopenalex-snapshot

Relay Zn( ii )- and Au( i )-catalyzed aziridination/cyclization/ring expansion sequence to form 3-benzazepine derivatives

inferred← citeshttps://doi.org/10.1039/d4ob01728eopenalex-snapshot

Sustainable protocol for Cu-catalysed A 3 -coupling under solvent-free conditions

inferred← citeshttps://doi.org/10.1039/d5cs00739aopenalex-snapshot

Advances in gold-catalyzed asymmetric alkyne functionalization

inferred← citeshttps://doi.org/10.1055/s-0042-1751383openalex-snapshot

Synthesis of 1H-Isochromenes and 1,2-Dihydroisoquinolines by Indium(III)-Catalyzed Cycloisomerization of ortho-(Alkynyl)benzyl Derivatives

inferred← citeshttps://doi.org/10.1055/sos-sd-115-00651openalex-snapshot

15.5.4 Isoquinolines (Update 2019)

inferred← citeshttps://doi.org/10.1080/00397911.2019.1703196openalex-snapshot

Ag-mediated synthesis of six-membered N-heterocycles

inferred← citeshttps://doi.org/10.1080/10426507.2011.604659openalex-snapshot

Efficient Syntheses of 1H-Isochromen-1-Ylmethylphosphonates via Regioselective 6-Endo-Dig Addition to Carbon—Carbon Triple Bond Catalyzed by Pd(OAc)2

inferred← citeshttps://doi.org/10.1080/15533174.2014.989620openalex-snapshot

Metal Catalysts for the Formation of Six-MemberedN-Polyheterocycles

inferred← citeshttps://doi.org/10.1177/1747519819871028openalex-snapshot

Synthesis of functionalized 1,2-dihydroisoquinolines via one-pot reactions of isoquinoline, alkyl propiolate, and thiazolidin-2,4-dione

inferred← citeshttps://doi.org/10.1201/9781351242615-9openalex-snapshot

Six-Membered Fused N-Heterocycles

inferred← citeshttps://doi.org/10.1246/bcsj.20190301openalex-snapshot

Catalytic Synthesis of Isoquinolines via Intramolecular Migration of N-Aryl Sulfonyl Groups on 1,5-Yne-Imines

inferred← citeshttps://doi.org/10.1246/bcsj.20200308openalex-snapshot

Development of Molecular Transformations on the Basis of Catalytic Generation of Anionic Species by Organosuperbase

inferred← citeshttps://doi.org/10.1246/cl.180200openalex-snapshot

Synthesis of 1,2-Dihydroisoquinolines via Rhenium-catalyzed Tandem Cyclization and Nucleophilic Addition of 2-(1-Alkynyl)arylaldimines

inferred← citeshttps://doi.org/10.3390/molecules27206970openalex-snapshot

Coinage Metal-Catalyzed Asymmetric Reactions of ortho-Alkynylaryl and Heteroaryl Aldehydes and Ketones

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