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Overcoming Resistance to β-Lactam Antibiotics

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/anie.201206911openalex-snapshot
Potent Small‐Molecule Suppression of Oxacillin Resistance in Methicillin‐Resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1002/cmdc.201100316openalex-snapshot
Evaluation of 4,5‐Disubstituted‐2‐Aminoimidazole–Triazole Conjugates for Antibiofilm/Antibiotic Resensitization Activity Against MRSA and Acinetobacter baumannii
inferredcites →https://doi.org/10.1002/cmdc.201200350openalex-snapshot
Structural Studies on 4,5‐Disubstituted 2‐Aminoimidazole‐Based Biofilm Modulators that Suppress Bacterial Resistance to β‐Lactams
inferredcites →https://doi.org/10.1007/s00018-004-4060-9openalex-snapshot
Resistance to ?-lactam antibiotics
inferredcites →https://doi.org/10.1016/j.bmcl.2003.12.037openalex-snapshot
Penicillin-derived inhibitors that simultaneously target both metallo- and serine-β-lactamases
inferredcites →https://doi.org/10.1016/j.bmcl.2012.08.012openalex-snapshot
2-Substituted 4,5-dihydrothiazole-4-carboxylic acids are novel inhibitors of metallo-β-lactamases
inferredcites →https://doi.org/10.1016/j.chembiol.2011.08.015openalex-snapshot
Antagonism of Chemical Genetic Interaction Networks Resensitize MRSA to β-Lactam Antibiotics
inferredcites →https://doi.org/10.1016/j.ijantimicag.2007.07.015openalex-snapshot
Introduction: historical perspective and development of amoxicillin/clavulanate
inferredcites →https://doi.org/10.1016/j.medmal.2008.09.031openalex-snapshot
The role of femA regulating gene on methicillin-resistant Staphylococcus aureus clinical isolates
inferredcites →https://doi.org/10.1016/j.mib.2010.01.008openalex-snapshot
Two-component signal transduction as potential drug targets in pathogenic bacteria
inferredcites →https://doi.org/10.1016/j.mib.2010.09.006openalex-snapshot
Alarming β-lactamase-mediated resistance in multidrug-resistant Enterobacteriaceae
inferredcites →https://doi.org/10.1016/j.mib.2010.09.008openalex-snapshot
The future of the β-lactams
inferredcites →https://doi.org/10.1016/j.mib.2011.07.026openalex-snapshot
Diazabicyclooctanes (DBOs): a potent new class of non-β-lactam β-lactamase inhibitors
inferredcites →https://doi.org/10.1016/j.resmic.2012.10.007openalex-snapshot
Thioridazine potentiates the effect of a beta-lactam antibiotic against Staphylococcus aureus independently of mecA expression
inferredcites →https://doi.org/10.1016/j.tibtech.2010.09.004openalex-snapshot
β-Lactam and glycopeptide antibiotics: first and last line of defense?
inferredcites →https://doi.org/10.1016/j.tim.2011.09.005openalex-snapshot
The emerging NDM carbapenemases
inferredcites →https://doi.org/10.1016/s0168-6445(99)00039-xopenalex-snapshot
Molecular basis of antibiotic resistance and β-lactamase inhibition by mechanism-based inactivators: perspectives and future directions
inferredcites →https://doi.org/10.1016/s1473-3099(11)70056-1openalex-snapshot
Metallo-β-lactamases: a last frontier for β-lactams?
inferredcites →https://doi.org/10.1021/cb100269fopenalex-snapshot
Synthetic Lethal Compound Combinations Reveal a Fundamental Connection between Wall Teichoic Acid and Peptidoglycan Biosyntheses in Staphylococcus aureus
inferredcites →https://doi.org/10.1021/cb300413mopenalex-snapshot
Inhibition of WTA Synthesis Blocks the Cooperative Action of PBPs and Sensitizes MRSA to β-Lactams
inferredcites →https://doi.org/10.1021/cr030102iopenalex-snapshot
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
inferredcites →https://doi.org/10.1021/ja00064a003openalex-snapshot
Inactivation of class A .beta.-lactamases by clavulanic acid: the role of arginine-244 in a proposed nonconcerted sequence of events
inferredcites →https://doi.org/10.1021/ja0434376openalex-snapshot
Activation for Catalysis of Penicillin-Binding Protein 2a from Methicillin-Resistant Staphylococcus aureus by Bacterial Cell Wall
inferredcites →https://doi.org/10.1021/ja073340uopenalex-snapshot
Structural and Initial Biological Analysis of Synthetic Arylomycin A2
inferredcites →https://doi.org/10.1021/ml200290popenalex-snapshot
Small Molecule Suppression of Carbapenem Resistance in NDM-1 Producing Klebsiella pneumoniae
inferredcites →https://doi.org/10.1021/ol202195nopenalex-snapshot
A Concise Synthesis of a β-Lactamase Inhibitor
inferredcites →https://doi.org/10.1038/nrmicro727openalex-snapshot
Where will new antibiotics come from?
inferredcites →https://doi.org/10.1039/c2ob25835hopenalex-snapshot
Small molecule control of bacterial biofilms
inferredcites →https://doi.org/10.1039/c2ob26469bopenalex-snapshot
N-Substituted 2-aminoimidazoleinhibitors of MRSA biofilm formation accessed through direct 1,3-bis(tert-butoxycarbonyl)guanidine cyclization
inferredcites →https://doi.org/10.1073/pnas.1205073109openalex-snapshot
Avibactam is a covalent, reversible, non–β-lactam β-lactamase inhibitor
inferredcites →https://doi.org/10.1073/pnas.122108599openalex-snapshot
The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)
inferredcites →https://doi.org/10.1073/pnas.54.4.1133openalex-snapshot
Mechanism of action of penicillins: a proposal based on their structural similarity to acyl-D-alanyl-D-alanine.
inferredcites →https://doi.org/10.1073/pnas.98.4.1427openalex-snapshot
A 1.2-Å snapshot of the final step of bacterial cell wall biosynthesis
inferredcites →https://doi.org/10.1074/jbc.m403589200openalex-snapshot
The Basis for Resistance to β-Lactam Antibiotics by Penicillin-binding Protein 2a of Methicillin-resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1074/jbc.m700084200openalex-snapshot
Small Molecule Inhibitors of a Glycoside Hydrolase Attenuate Inducible AmpC-mediated β-Lactam Resistance
inferredcites →https://doi.org/10.1093/jac/39.suppl_1.47openalex-snapshot
Suppression of beta-lactam antibiotic resistance in a methicillin- resistant Staphylococcus aureus through synergic action of early cell wall inhibitors and some other antibiotics
inferredcites →https://doi.org/10.1093/jac/45.3.271openalex-snapshot
In vitro antibacterial activity and mechanism of action of J-111,225, a novel 1β-methylcarbapenem, against transferable IMP-1 metallo-β-lactamase producers
inferredcites →https://doi.org/10.1093/jac/dkl519openalex-snapshot
Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to β-lactams in methicillin-resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1093/jac/dkn417openalex-snapshot
Reversal of methicillin resistance in Staphylococcus aureus by thioridazine
inferredcites →https://doi.org/10.1093/jac/dkq217openalex-snapshot
The 2009 Garrod Lecture: The evolution of antimicrobial resistance: a Darwinian perspective
inferredcites →https://doi.org/10.1093/jac/dkq520openalex-snapshot
Does broad-spectrum -lactam resistance due to NDM-1 herald the end of the antibiotic era for treatment of infections caused by Gram-negative bacteria?
inferredcites →https://doi.org/10.1111/j.1469-0691.2006.01456.xopenalex-snapshot
Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology
inferredcites →https://doi.org/10.1111/j.1574-6968.2011.02255.xopenalex-snapshot
Thioridazine affects transcription of genes involved in cell wall biosynthesis in methicillin-resistant Staphylococcus aureus
inferredcites →https://doi.org/10.1111/j.1742-4658.2009.07037.xopenalex-snapshot
Enzymatic investigation of the Staphylococcus aureus type I signal peptidase SpsB – implications for the search for novel antibiotics
inferredcites →https://doi.org/10.1111/j.1749-6632.2012.06813.xopenalex-snapshot
Bacterial cell‐wall recycling
inferredcites →https://doi.org/10.1126/science.1159961openalex-snapshot
An Inhibitor of FtsZ with Potent and Selective Anti-Staphylococcal Activity
inferredcites →https://doi.org/10.1126/scitranslmed.3003592openalex-snapshot
Restoring Methicillin-Resistant Staphylococcus aureus Susceptibility to β-Lactam Antibiotics
inferredcites →https://doi.org/10.1128/aac.00085-08openalex-snapshot
In Vitro Activity of LK-157, a Novel Tricyclic Carbapenem As Broad-Spectrum β-Lactamase Inhibitor
inferredcites →https://doi.org/10.1128/aac.00356-06openalex-snapshot
Role of VraSR in Antibiotic Resistance and Antibiotic-Induced Stress Response in Staphylococcus aureus
inferredcites →https://doi.org/10.1128/aac.00385-10openalex-snapshot
NagZ Inactivation Prevents and Reverts β-Lactam Resistance, Driven by AmpD and PBP 4 Mutations, in Pseudomonas aeruginosa
inferredcites →https://doi.org/10.1128/aac.00726-12openalex-snapshot
Broadening the Spectrum of β-Lactam Antibiotics through Inhibition of Signal Peptidase Type I
inferredcites →https://doi.org/10.1128/aac.01009-09openalex-snapshot
Updated Functional Classification of β-Lactamases
inferredcites →https://doi.org/10.1128/aac.01370-10openalex-snapshot
In Vitro and In Vivo Properties of BAL30376, a β-Lactam and Dual β-Lactamase Inhibitor Combination with Enhanced Activity against Gram-Negative Bacilli That Express Multiple β-Lactamases
inferredcites →https://doi.org/10.1128/aac.01418-09openalex-snapshot
Synergistic Effects between Conventional Antibiotics and 2-Aminoimidazole-Derived Antibiofilm Agents
inferredcites →https://doi.org/10.1128/aac.01549-08openalex-snapshot
Efficacy of Piperacillin Combined with the Penem β-Lactamase Inhibitor BLI-489 in Murine Models of Systemic Infection
inferredcites →https://doi.org/10.1128/aac.01704-10openalex-snapshot
Improved Oxacillin Treatment Outcomes in Experimental Skin and Lung Infection by a Methicillin-Resistant Staphylococcus aureus Isolate with a vraSR Operon Deletion
inferredcites →https://doi.org/10.1128/aac.05927-11openalex-snapshot
In Vitro Activity of MK-7655, a Novel β-Lactamase Inhibitor, in Combination with Imipenem against Carbapenem-Resistant Gram-Negative Bacteria
inferredcites →https://doi.org/10.1128/aac.43.10.2497openalex-snapshot
Carbapenem Derivatives as Potential Inhibitors of Various β-Lactamases, Including Class B Metallo-β-Lactamases
inferredcites →https://doi.org/10.1128/cmr.00037-09openalex-snapshot
Three Decades of β-Lactamase Inhibitors
inferredcites →https://doi.org/10.1139/w2012-043openalex-snapshot
Chromatin immunoprecipitation identifies genes under direct VraSR regulation in Staphylococcus aureus
inferredcites →https://doi.org/10.1371/journal.pone.0048981openalex-snapshot
The Nonantibiotic Small Molecule Cyslabdan Enhances the Potency of β-Lactams against MRSA by Inhibiting Pentaglycine Interpeptide Bridge Synthesis
inferredcites →https://doi.org/10.1517/13543776.2010.515588openalex-snapshot
New β-lactam antibiotics and β-lactamase inhibitors
inferredcites →https://doi.org/10.4065/74.3.290openalex-snapshot
The Penicillins

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Design and Development of Efficient Synthetic Strategies for Novel B-Lactamase Enhancer: WCK 5153 Effective Against Gram-Negative Pathogens
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Design and Development of Efficient Synthetic Strategies for Novel B-Lactam Enhancer Wck 5153 Effective Against Gram-Negative Pathogens
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β‐Lactam Synthesis through Diodomethane Addition to Amide Dianions
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β‐Lactam Synthesis through Diodomethane Addition to Amide Dianions
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Semisynthesis: An Essential Tool for Antibiotics Drug Discovery
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β‐Lactam resistance genes present in UK pheasants and red‐legged partridges
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Strategies for Circumventing Bacterial Resistance Mechanisms
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Combination of Drugs: An Effective Approach for Enhancing the Efficacy of Antibiotics to Combat Drug Resistance
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Prospects of biosynthesized nanoparticles in treating pharmaceutical wastewater in relation to human health
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Nanomaterial-mediated synthesis of β-lactams and exploration of their enhanced biological activities: recent advances
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Enzymatic biosynthesis of β-lactam antibiotics
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Lactamase and antibiotic resistance: A catalyst for drug discovery breakthroughs
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Antibiotic targeting of the bacterial secretory pathway
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Structural analysis of the CARB β-lactamase from Vibrio parahaemolyticus facilitates application of the β-lactam/β-lactamase inhibitor therapy
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The sentinel role of peptidoglycan recycling in the β-lactam resistance of the Gram-negative Enterobacteriaceae and Pseudomonas aeruginosa
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Azetidinimines as a novel series of non-covalent broad-spectrum inhibitors of β-lactamases with submicromolar activities against carbapenemases KPC-2 (class A), NDM-1 (class B) and OXA-48 (class D)
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Design and development of efficient synthetic strategies for novel β-lactam enhancer WCK 5153 effective against gram-negative pathogens
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Recent advances in the syntheses and reactions of biologically promising β-lactam derivatives
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The Effects of β-Lactam Antibiotics on Surface Modifications of Multidrug-Resistant Escherichia coli: A Multiscale Approach
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Multiscale Simulations of Clavulanate Inhibition Identify the Reactive Complex in Class A β-Lactamases and Predict the Efficiency of Inhibition
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An Efficient Computational Assay for β-Lactam Antibiotic Breakdown by Class A β-Lactamases
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N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases
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Proteomic Changes in Methicillin-Resistant Staphylococcus aureus Exposed to Cannabinoids
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Diastereoselective Synthesis of β-Lactams by Ligand-Controlled Stereodivergent Intramolecular Tsuji–Trost Allylation
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3-Diazopiperidine-2,4-diones as Convenient Precursors to Rare Polysubstituted Spiro Bis-β,γ-lactams and 2-Oxopyrrolidine-3-carboxylic Acid Derivatives via the Thermally Promoted Wolff Rearrangement
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Stereoselective Synthesis of Diazabicyclic β-Lactams through Intramolecular Amination of Unactivated C(sp3)–H Bonds of Carboxamides by Palladium Catalysis
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Alternate “Drug” Delivery Utilizing β-Lactam Cores: Syntheses and Biological Evaluation of β-Lactams Bearing Isocyanate Precursors
inferred← citeshttps://doi.org/10.1021/acsanm.4c03682openalex-snapshot
Low-Temperature Base-Catalyzed Si-Capped ZnO Quantum Dots for pH-Switchable Dual Sensing of Amoxicillin and Cr3+
inferred← citeshttps://doi.org/10.1021/acsinfecdis.0c00307openalex-snapshot
A Clerodane Diterpene from Callicarpa americana Resensitizes Methicillin-Resistant Staphylococcus aureus to β‑Lactam Antibiotics
inferred← citeshttps://doi.org/10.1021/acsinfecdis.7b00094openalex-snapshot
Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.1c00635openalex-snapshot
NMR Backbone Assignment of VIM-2 and Identification of the Active Enantiomer of a Potential Inhibitor
inferred← citeshttps://doi.org/10.1021/acsomega.2c08206openalex-snapshot
Synthesis of α-CF3 Amides via Palladium-Catalyzed Carbonylation of 2-Bromo-3,3,3-trifluoropropene
inferred← citeshttps://doi.org/10.1021/bi400873ropenalex-snapshot
Kinetics of Action of a Two-Stage Pro-Inhibitor of Serine β-Lactamases
inferred← citeshttps://doi.org/10.1021/jm500146gopenalex-snapshot
Structure–Activity Relationship Studies of the Tricyclic Indoline Resistance-Modifying Agent
inferred← citeshttps://doi.org/10.1038/s41429-022-00566-yopenalex-snapshot
In vitro activity of celastrol in combination with thymol against carbapenem-resistant Klebsiella pneumoniae isolates
inferred← citeshttps://doi.org/10.1038/s41429-024-00769-5openalex-snapshot
The effect of novel β-lactam derivatives synthesized from substituted phenethylamines on resistance genes of MRSA isolates
inferred← citeshttps://doi.org/10.1038/s41467-024-53192-7openalex-snapshot
Innovative approaches in phenotypic beta-lactamase detection for personalised infection management
inferred← citeshttps://doi.org/10.1038/s41564-019-0471-0openalex-snapshot
Genomic identification of cryptic susceptibility to penicillins and β-lactamase inhibitors in methicillin-resistant Staphylococcus aureus
inferred← citeshttps://doi.org/10.1038/s41598-020-69039-2openalex-snapshot
Recombinant expression, purification and PEGylation of Paneth cell peptide (cryptdin-2) with value added attributes against Staphylococcus aureus
inferred← citeshttps://doi.org/10.1038/srep28168openalex-snapshot
Combination therapy with polymyxin B and netropsin against clinical isolates of multidrug-resistant Acinetobacter baumannii
inferred← citeshttps://doi.org/10.1039/9781782620938-00177openalex-snapshot
Fragment-Based Discovery of Antibacterials
inferred← citeshttps://doi.org/10.1039/c6ob02221aopenalex-snapshot
Diastereoselective synthesis of 3-acetoxy-4-(3-aryloxiran-2-yl)azetidin-2-ones and their transformation into 3,4-oxolane-fused bicyclic β-lactams
inferred← citeshttps://doi.org/10.1039/c8nj01034jopenalex-snapshot
Design and development of novel antibiotics based on FtsZ inhibition – in silico studies
inferred← citeshttps://doi.org/10.1039/d0cc04415fopenalex-snapshot
Synthesis of β- and γ-lactam fused dihydropyrazinones from Ugi adducts via a sequential ring construction strategy
inferred← citeshttps://doi.org/10.1039/d0qm00874eopenalex-snapshot
Smart active antibiotic nanocarriers with protease surface functionality can overcome biofilms of resistant bacteria
inferred← citeshttps://doi.org/10.1039/d0sc01232gopenalex-snapshot
Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
inferred← citeshttps://doi.org/10.1039/d1nr08157hopenalex-snapshot
Emerging nanotechnologies for targeting antimicrobial resistance
inferred← citeshttps://doi.org/10.1039/d1sc02212aopenalex-snapshot
A general strategy for the synthesis of α-trifluoromethyl- and α-perfluoroalkyl-β-lactams via palladium-catalyzed carbonylation
inferred← citeshttps://doi.org/10.1039/d2nj03915jopenalex-snapshot
The rapid synthesis of intrinsic green-fluorescent poly(pyrogallol)-derived carbon dots for amoxicillin drug sensing in clinical samples
inferred← citeshttps://doi.org/10.1039/d5ob01913copenalex-snapshot
Synthesis of α-trifluoromethyl-β-lactams via a copper-catalyzed Kinugasa reaction of nitrones with 3,3,3-trifluoropropyne and their defluorination
inferred← citeshttps://doi.org/10.1055/s-0037-1611851openalex-snapshot
Heterogeneous Catalysis with Basic Compounds to Achieve the Synthesis and C–N Cleavage of Azetidin-2-ones under Microwave Irradiation
inferred← citeshttps://doi.org/10.1055/s-0039-1693498openalex-snapshot
Pharmacokinetics/Pharmacodynamics of β-Lactams and Therapeutic Drug Monitoring: From Theory to Practical Issues in the Intensive Care Unit
inferred← citeshttps://doi.org/10.1073/pnas.2012800118openalex-snapshot
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
inferred← citeshttps://doi.org/10.1080/00958972.2014.938065openalex-snapshot
A complex of ceftriaxone with Pb(II): synthesis, characterization, and antibacterial activity study
inferred← citeshttps://doi.org/10.1080/07391102.2025.2563080openalex-snapshot
Mechanistic insights into ESBL activity of subclass A2 in Class A beta-lactamase revealing a distinct strategy towards conferring drug resistance
inferred← citeshttps://doi.org/10.1080/08927014.2020.1833192openalex-snapshot
Variability in in vitro biofilm production and antimicrobial sensitivity pattern among Pasteurella multocida strains
inferred← citeshttps://doi.org/10.1080/08927022.2023.2232468openalex-snapshot
Rational design of novel compounds to serve as potential NDM-1 inhibitors using molecular docking, molecular dynamics simulation, and physicochemical studies
inferred← citeshttps://doi.org/10.1080/13543776.2022.2116312openalex-snapshot
A patent review of pharmaceutical and therapeutic applications of oxadiazole derivatives for the treatment of chronic diseases (2013–2021)
inferred← citeshttps://doi.org/10.1080/20002297.2025.2508479openalex-snapshot
Amoxicillin-metronidazole disk for antimicrobial susceptibility testing of subgingival bacteria
inferred← citeshttps://doi.org/10.1080/21505594.2025.2514092openalex-snapshot
Enterobacterales use capsules, transporters, mobile genetic elements, and other evolutionary adaptations to survive antibiotics exposure in the absence of resistance genes
inferred← citeshttps://doi.org/10.1080/22221751.2019.1692638openalex-snapshot
Dual activity of PNGM-1 pinpoints the evolutionary origin of subclass B3 metallo- β -lactamases: a molecular and evolutionary study
inferred← citeshttps://doi.org/10.1089/mdr.2020.0590openalex-snapshot
Detection of Antimicrobial and Heavy-Metal Resistance Genes in Aeromonas spp. Isolated from Hard-Shelled Mussel ( Mytilus Coruscus )
inferred← citeshttps://doi.org/10.1089/mdr.2022.0094openalex-snapshot
First Detection of Extensively Drug-Resistant Salmonella Typhi Isolates Harboring VIM and GES Genes for Carbapenem Resistance from Faisalabad, Pakistan
inferred← citeshttps://doi.org/10.1093/ajhp/zxad232openalex-snapshot
Physical compatibility of sulbactam/durlobactam with select intravenous drugs during simulated Y-site administration
inferred← citeshttps://doi.org/10.1093/bioinformatics/btad717openalex-snapshot
Multimodal learning in clinical proteomics: enhancing antimicrobial resistance prediction models with chemical information
inferred← citeshttps://doi.org/10.1093/femsle/fnad053openalex-snapshot
Microbiological quality, antibiotic resistant bacteria and relevant resistance genes in ready-to-eat Pacific oysters (Magallana gigas)
inferred← citeshttps://doi.org/10.1093/femsmc/xtae004openalex-snapshot
Prevalence of diverse antimicrobial resistance genes and bacteria in sewage treatment plant-derived sludge environment
inferred← citeshttps://doi.org/10.1093/jac/dkae455openalex-snapshot
NaHCO3 modulates the bla operon and β-lactam susceptibility in borderline oxacillin-resistant Staphylococcus aureus (BORSA)
inferred← citeshttps://doi.org/10.1093/protein/gzab013openalex-snapshot
Evolution of β-lactamases and enzyme promiscuity
inferred← citeshttps://doi.org/10.1101/2022.10.25.513716openalex-snapshot
Gating interactions steer loop conformational changes in the active site of the L1 metallo-β-lactamase
inferred← citeshttps://doi.org/10.1101/2023.12.15.571804openalex-snapshot
Genomic, Epigenomic, and Transcriptional Characterisation of Carbapenem and Colistin Resistance Mechanisms in Klebsiella pneumoniae and Enterobacter species
inferred← citeshttps://doi.org/10.1111/apm.70002openalex-snapshot
The EUCAST Disk Diffusion Method for Antimicrobial Susceptibility Testing of Oral Anaerobes
inferred← citeshttps://doi.org/10.1128/aac.04634-14openalex-snapshot
Fast and Accurate Large-Scale Detection of β-Lactamase Genes Conferring Antibiotic Resistance
inferred← citeshttps://doi.org/10.1128/iai.00756-19openalex-snapshot
Klebsiella pneumoniae Expressing VIM-1 Metallo-β-Lactamase Is Resensitized to Cefotaxime via Thiol-Mediated Zinc Chelation
inferred← citeshttps://doi.org/10.1128/mbio.01851-22openalex-snapshot
Phage-Plasmids Spread Antibiotic Resistance Genes through Infection and Lysogenic Conversion
inferred← citeshttps://doi.org/10.1128/mbio.02412-19openalex-snapshot
A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions
inferred← citeshttps://doi.org/10.1128/spectrum.00391-24openalex-snapshot
Functional and structural analyses of IMP-27 metallo-β-lactamase: evolution of IMP-type enzymes to overcome Zn(II) deprivation
inferred← citeshttps://doi.org/10.1128/spectrum.02382-24openalex-snapshot
Exogenous adenosine counteracts tigecycline resistance in tet (X3)-harboring Escherichia coli
inferred← citeshttps://doi.org/10.1134/s1068162019040125openalex-snapshot
Synthesis and In Vitro Antibacterial Activity of New C-3-Modified Carbapenems
inferred← citeshttps://doi.org/10.1134/s1070428016030106openalex-snapshot
Pyrrolidine synthons for β-lactams
inferred← citeshttps://doi.org/10.1134/s1070428016070058openalex-snapshot
Functionalized β-lactams based on (E)-1-(furan-2-yl)-N-[(4-methoxyphenyl)methyl]methanimine and its imine–imine rearrangement initiated by potassium hydride
inferred← citeshttps://doi.org/10.1134/s1070428018070096openalex-snapshot
(2R,3R)-3-[(1R)-1-{[tert-Butyl(dimethyl)silyl]oxy}ethyl]-4-oxoazetidin-2-yl Acetate in Zinc- and Samarium-Promoted Substitution Reactions with Methyl 2-Bromopropanoate and Methyl (2-Bromomethyl)prop-2-enoate. Unusual Cleavage of the N1‒C4 Bond in Azetidin-2-one Derivative with Migration of…
inferred← citeshttps://doi.org/10.1134/s1070428018110076openalex-snapshot
Methyl 2-(Bromomethyl)acrylate, Methyl Acrylate, and Glycine in the Synthesis of Functionalized Pyrrolidones
inferred← citeshttps://doi.org/10.1134/s1070428021090116openalex-snapshot
β-Lactam Ring Opening in the Reformatsky Reaction of (3R,4R)-4-Acetoxy-3-((1R)-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl)azetidin-2-one with Ethyl 4-Bromo-3-oxopentanoate
inferred← citeshttps://doi.org/10.1134/s1070428022110203openalex-snapshot
Synthesis of (3S,4S)-4-Acetyl-3-(1R)-1-hydroxyethyl-1-(4-methoxyphenyl)azetidin-2-one
inferred← citeshttps://doi.org/10.1149/2162-8777/ad397fopenalex-snapshot
Biogenic Zinc Oxide Nanoparticles: An Insight into the Advancements in Antimicrobial Resistance
inferred← citeshttps://doi.org/10.1155/joch/4427650openalex-snapshot
Design, Synthesis, and In Vitro and In Silico Biological Exploration of Novel Pyridine‐Embedded 1,3,4‐Oxadiazole Hybrids as Potential Antimicrobial Agents
inferred← citeshttps://doi.org/10.1186/s12866-024-03577-xopenalex-snapshot
Synergistic potential of Leu10-teixobactin and cefepime against multidrug-resistant Staphylococcus aureus
inferred← citeshttps://doi.org/10.1186/s12879-018-3581-zopenalex-snapshot
Prevalence of metallo-β-lactamase acquired genes among carbapenems susceptible and resistant Gram-negative clinical isolates using multiplex PCR, Khartoum hospitals, Khartoum Sudan
inferred← citeshttps://doi.org/10.1186/s40545-016-0083-5openalex-snapshot
Towards the just and sustainable use of antibiotics
inferred← citeshttps://doi.org/10.1186/s43141-021-00263-7openalex-snapshot
Exploitation of E. coli for the production of penicillin G amidase: a tool for the synthesis of semisynthetic β-lactam antibiotics
inferred← citeshttps://doi.org/10.13023/etd.2021.275openalex-snapshot
Investigation of Multidrug Efflux Transporter AcrB in Escherichia coli
inferred← citeshttps://doi.org/10.1371/journal.pdig.0001593openalex-snapshot
Machine learning-based quantitative structure–activity relationship model for antibiotic prediction and discovery
inferred← citeshttps://doi.org/10.1371/journal.pone.0180925openalex-snapshot
2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability
inferred← citeshttps://doi.org/10.1371/journal.pone.0275237openalex-snapshot
In silico designing and immunoinformatics analysis of a novel peptide vaccine against metallo-beta-lactamase (VIM and IMP) variants
inferred← citeshttps://doi.org/10.14202/vetworld.2024.216-225openalex-snapshot
Kinship analysis of mecA gene of methicillin-resistant Staphylococcus aureus isolated from milk and risk factors from the farmers in Blitar, Indonesia
inferred← citeshttps://doi.org/10.17760/d20317952openalex-snapshot
Preparation of nanoparticles by green synthesis and a study on their antibacterial and anticancer properties
inferred← citeshttps://doi.org/10.19080/omcij.2017.02.555597openalex-snapshot
Promoted by Samarium Reaction of (3r,4r)-3-((1r)- 1-{[Tert-Butyl(dimethyl)Silyl]oxy}Ethyl)-4-AcetoxyAzetidin-2-one with Methyl 2-Bromopropianate. Unusual Decyclization of Azetidin-2-one Derivative in Approaches to Carbapenems Analogues
inferred← citeshttps://doi.org/10.19261/cjm.2019.647openalex-snapshot
Novel Β-lactams and Thiazolidinone Derivatives from 1,4-dihydroquinoxaline Schiff’s Base: Synthesis, Antimicrobial Activity and Molecular Docking Studies
inferred← citeshttps://doi.org/10.2147/idr.s226215openalex-snapshot
Virulence and Resistance Determinants of Uropathogenic Escherichia coli Strains Isolated from Pregnant and Non-Pregnant Women from Two States in Mexico
inferred← citeshttps://doi.org/10.2147/rmhp.s291876openalex-snapshot
Extended-Spectrum Beta-Lactamase-Producing Gram-Negative Bacteria on Healthcare Workers’ Mobile Phones: Evidence from Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia
inferred← citeshttps://doi.org/10.2174/1389450120666181217101812openalex-snapshot
Recent Review on Subclass B1 Metallo-β-lactamases Inhibitors: Sword for Antimicrobial Resistance
inferred← citeshttps://doi.org/10.2174/1568026623666230504095005openalex-snapshot
AmpC Inhibition: An Explicit Approach against Multi-Drug Resistance (MDR)
inferred← citeshttps://doi.org/10.23889/suthesis.66753openalex-snapshot
Identifying Host and Bacterial Biomarkers to Predict Sepsis
inferred← citeshttps://doi.org/10.24820/ark.5550190.p011.437openalex-snapshot
Synthesis and structure determination of diastereomeric carbapenems in the AdNE-reaction of (±)-4,4-dimethyl-3-mercaptodihydrofuran-2(3H)-one with chiral carbapenem enol phosphate
inferred← citeshttps://doi.org/10.26434/chemrxiv.11897157openalex-snapshot
Azetidinimines as a Novel Series of Non-Covalent Broad-Spectrum Inhibitors of β-Lactamases with Submicromolar Activities Against Carbapenemases of Classes A, B and D
inferred← citeshttps://doi.org/10.3109/14756366.2015.1058257openalex-snapshot
Monocyclicβ-lactam and unexpected oxazinone formation: synthesis, crystal structure, docking studies and antibacterial evaluation
inferred← citeshttps://doi.org/10.31857/s0514749223010111openalex-snapshot
Synthesis of (3S,4S)-4-Acetyl-3-(1R)-1-hydroxyethyl1-(4-methoxyphenyl)azetidin-2-one
inferred← citeshttps://doi.org/10.32598/jams.22.6.2891.1openalex-snapshot
Frequency of TEM and PER Beta-Lactamase Genes in Urinary Isolates of Escherichia Coli Producing Extended-Spectrum Beta-Lactamases
inferred← citeshttps://doi.org/10.33003/fjs-2020-0403-188openalex-snapshot
CO-PRODUCTION OF EXTENDED-SPECTRUM BETA-LACTAMASES AND METALLO BETA-LACTAMASES AMONG MULTI-DRUG RESISTANT GRAM-NEGATIVE BACTERIA ISOLATES COLLECTED FROM TERTIARY HOSPITALS IN OYO STATE, NIGERIA
inferred← citeshttps://doi.org/10.3389/fmicb.2020.00067openalex-snapshot
Resistome in Lake Bolonha, Brazilian Amazon: Identification of Genes Related to Resistance to Broad-Spectrum Antibiotics
inferred← citeshttps://doi.org/10.3389/fmicb.2024.1466353openalex-snapshot
Metagenomics insights into bacterial diversity and antibiotic resistome of the sewage in the city of Belém, Pará, Brazil
inferred← citeshttps://doi.org/10.3389/fphar.2023.1158152openalex-snapshot
Bifunctional antibiotic hybrids: A review of clinical candidates
inferred← citeshttps://doi.org/10.3390/antibiotics10111429openalex-snapshot
Effect of Imipenem and Amikacin Combination against Multi-Drug Resistant Pseudomonas aeruginosa
inferred← citeshttps://doi.org/10.3390/antibiotics12020348openalex-snapshot
Pseudomonas aeruginosa and Staphylococcus aureus Display Differential Proteomic Responses to the Silver(I) Compound, SBC3
inferred← citeshttps://doi.org/10.3390/antibiotics13070679openalex-snapshot
Antimicrobial Resistance Elements in Coastal Water of Llanquihue Lake, Chile
inferred← citeshttps://doi.org/10.3390/antibiotics3020128openalex-snapshot
Molecular Targets of β-Lactam-Based Antimicrobials: Beyond the Usual Suspects
inferred← citeshttps://doi.org/10.3390/antibiotics3020193openalex-snapshot
β-Lactam Antibiotics Renaissance
inferred← citeshttps://doi.org/10.3390/antibiotics5030028openalex-snapshot
The Membrane Steps of Bacterial Cell Wall Synthesis as Antibiotic Targets
inferred← citeshttps://doi.org/10.3390/antibiotics9060296openalex-snapshot
Beta-Lactam Sensitive Bacteria Can Acquire ESBL-Resistance via Conjugation after Long-Term Exposure to Lethal Antibiotic Concentration
inferred← citeshttps://doi.org/10.3390/applmicrobiol3030060openalex-snapshot
Antibiotic Resistance Patterns of Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa Isolated from Hospital Wastewater
inferred← citeshttps://doi.org/10.3390/biom10081094openalex-snapshot
4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-β-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition
inferred← citeshttps://doi.org/10.3390/catal12050537openalex-snapshot
Different Chiral Ligands Assisted Enantioselective C-H Functionalization with Transition-Metal Catalysts
inferred← citeshttps://doi.org/10.3390/cryst10050339openalex-snapshot
Novel Quaternary Ammonium Derivatives of 4-Pyrrolidino Pyridine: Synthesis, Structural, Thermal, and Antibacterial Studies
inferred← citeshttps://doi.org/10.3390/engproc2023059146openalex-snapshot
Identifying Antibiotic-Resistant Mutants in β-Lactamases for Class A and Class B Using Unsupervised Machine Learning
inferred← citeshttps://doi.org/10.3390/foods14020224openalex-snapshot
Prevalence, Characterization, and Proteomic Relatedness Among β-Lactam-Resistant Bacteria Throughout the Poultry Production Chain in Greece
inferred← citeshttps://doi.org/10.3390/genes8010039openalex-snapshot
The Complex Relationship between Virulence and Antibiotic Resistance
inferred← citeshttps://doi.org/10.3390/membranes12100981openalex-snapshot
The Role of Outer Membrane Proteins in UPEC Antimicrobial Resistance: A Systematic Review
inferred← citeshttps://doi.org/10.3390/microorganisms11041052openalex-snapshot
Capture ELISA for KPC Detection in Gram-Negative Bacilli: Development and Standardisation
inferred← citeshttps://doi.org/10.3390/microorganisms11112728openalex-snapshot
Two-Dose Ceftiofur Treatment Increases Cephamycinase Gene Quantities and Fecal Microbiome Diversity in Dairy Cows Diagnosed with Metritis
inferred← citeshttps://doi.org/10.3390/microorganisms12040723openalex-snapshot
Prevalence of Extended-Spectrum β-Lactamases (ESBLs) Producing Aeromonas spp. Isolated from Lamellidens marginalis (Lamark, 1819) of Sewage-Fed Wetland: A Phenotypic and Genotypic Approach
inferred← citeshttps://doi.org/10.3390/microorganisms8050708openalex-snapshot
Occurrence of blaTEM and blaCTXM Genes and Biofilm-Forming Ability among Clinical Isolates of Pseudomonas aeruginosa and Acinetobacter baumannii in Yaoundé, Cameroon
inferred← citeshttps://doi.org/10.3390/molecules25051248openalex-snapshot
On Column Binding a Real-Time Biosensor for β-lactam Antibiotics Quantification
inferred← citeshttps://doi.org/10.3390/molecules28104183openalex-snapshot
Combating Antimicrobial Resistance in the Post-Genomic Era: Rapid Antibiotic Discovery
inferred← citeshttps://doi.org/10.3390/molecules29122869openalex-snapshot
Spermacoce alata Aubl. Essential Oil: Chemical Composition, In Vitro Antioxidant Activity, and Inhibitory Effects of Acetylcholinesterase, α-Glucosidase and β-Lactamase
inferred← citeshttps://doi.org/10.3390/pathogens11121420openalex-snapshot
Drug Repurposing Approaches towards Defeating Multidrug-Resistant Gram-Negative Pathogens: Novel Polymyxin/Non-Antibiotic Combinations
inferred← citeshttps://doi.org/10.3762/bjoc.10.195openalex-snapshot
Application of cyclic phosphonamide reagents in the total synthesis of natural products and biologically active molecules
inferred← citeshttps://doi.org/10.3923/jm.2017.97.101openalex-snapshot
A Role of Loop 1 in BPU-1: A Class D β-lactamase from Gram-positive Bacteria
inferred← citeshttps://doi.org/10.4018/979-8-3693-1540-8.ch009openalex-snapshot
Recent Strategies Inhibiting Quorum Sensing and Biofilm Formation in Bacteria to Combat Antibacterial Drug Resistance
inferred← citeshttps://doi.org/10.4103/ijmm.ijmm_18_326openalex-snapshot
Newer β-Lactam/β-Lactamase Inhibitor for Multidrug-Resistant Gram-Negative Infections: Challenges, Implications and Surveillance Strategy for India
inferred← citeshttps://doi.org/10.5772/intechopen.70199openalex-snapshot
Toxicity of β-Lactam Antibiotics: Pathophysiology, Molecular Biology and Possible Recovery Strategies
inferred← citeshttps://doi.org/10.58837/chula.the.2019.1152openalex-snapshot
การพฒนาเทคนค RECOMBINASE POLYMERASE AMPLIFICATION และ HELICASE DEPENDENT ISOTHERMAL AMPLIFICATION สำหรบตรวจจโนไทปของเอนไซม EXTENDED-SPECTRUM β-LACTAMASE ทสรางจากเชอ Escherichia coli ในสถาบนมะเรงแหงชาต ประเทศไทย
inferred← citeshttps://doi.org/10.63028/10067/2051610151162165141openalex-snapshot
Investigating Mtr and MshC as potential targets in the fight against Mycobacterium abscessus infections
inferred← citeshttps://doi.org/10.70675/611f2f72z55c9z4827zabc8z37ace89b43f1openalex-snapshot
Inhibiteurs d'enzymes à visée antimicrobienne : SUB1, une nouvelle cible pour lutter contre le paludisme. Métallo-β-lactamases, lutter contre la résistance bactérienne aux antibiotiques
inferred← citeshttps://doi.org/10.7759/cureus.36078openalex-snapshot
An In Vitro Susceptibility Study of Cefotaxime-Sulbactam on Clinical Bacterial Isolates From Various Regions in India: A Comparison With Ceftriaxone-Sulbactam
inferred← citeshttps://doi.org/10.7868/s0514749218070099openalex-snapshot
(2R,3R)-3-[(1R)-1-{[трет-БУТИЛ(ДИМЕТИЛ)СИЛИЛ]ОКСИ}ЭТИЛ]-4-ОКСOАЗЕТИДИН-2-ИЛ АЦЕТАТ В ИНДУЦИРУЕМЫХ Zn И Sm РЕАКЦИЯХ ЗАМЕЩЕНИЯ С МЕТИЛ 2-БРОМПРОПИОНАТОМ И МЕТИЛ (2-БРОММЕТИЛ)ПРОП-2-ЕНОАТОМ. НЕОБЫЧНОЕ РАСЩЕПЛЕНИЕ СВЯЗИ N1-C4 ПРОИЗВОДНОГО АЗЕТИДИН-2-ОНА С МИГ
inferred← citeshttps://doi.org/10.82308/5190openalex-snapshot
Examining the antibiotic potentiating activity of cranberry-derived proanthocyanidins against β-lactam resistant bacteria
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