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Using NMR Chemical Shift Imaging To Monitor Swelling and Molecular Transport in Drug-Loaded Tablets of Hydrophobically Modified Poly(acrylic acid): Methodology and Effects of Polymer (In)solubility

https://doi.org/10.1021/la4024458
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Dissolution Rate Enhancement of Parabens in PEG Solid Dispersions and Its Influence on the Release from Hydrophilic Matrix Tablets
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Controlled Drug Release from Gels Using Lipophilic Interactions of Charged Substances with Surfactants and Polymers
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Structure and behaviour in hydrophilic matrix sustained release dosage forms: 2. NMR-imaging studies of dimensional changes in the gel layer and core of HPMC tablets undergoing hydration
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Analysis of the swelling and release mechanisms from drug delivery systems with emphasis on drug solubility and water transport
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Swelling-controlled release in hydrogel matrices for oral route
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Influence of ionic strength on matrix integrity and drug release from hydroxypropyl cellulose compacts
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Pharmaceutical applications of magnetic resonance imaging (MRI)
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MRI as a tool for evaluation of oral controlled release dosage forms
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Quantitative evaluation of polymer concentration profile during swelling of hydrophilic matrix tablets using H NMR and MRI methods
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Magnetic resonance imaging and X-ray microtomography studies of a gel-forming tablet formulation
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Swelling and erosion properties of hydroxypropylmethylcellulose (Hypromellose) matrices—influence of agitation rate and dissolution medium composition
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New release cell for NMR microimaging of tablets
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Quantitative magnetic resonance micro-imaging methods for pharmaceutical research
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Mechanistic modelling of drug release from polymer-coated and swelling and dissolving polymer matrix systems
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Chemical shift imaging of molecular transport in colloidal systems: Visualization and quantification of diffusion processes
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Chemical shift imaging NMR to track gel formation
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A model for the drug release from a polymer matrix tablet—effects of swelling and dissolution
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Polymer mobilization and drug release during tablet swelling. A 1H NMR and NMR microimaging study
inferredcites →https://doi.org/10.1016/j.jconrel.2009.05.017openalex-snapshot
The extended release properties of HPMC matrices in the presence of dietary sugars
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Mapping the intracellular fraction of water by varying the gradient pulse length in q-space diffusion MRI
inferredcites →https://doi.org/10.1016/j.rinphs.2013.08.001openalex-snapshot
Surfactants modify the release from tablets made of hydrophobically modified poly (acrylic acid)
inferredcites →https://doi.org/10.1016/j.ssnmr.2003.03.016openalex-snapshot
The swelling properties of hydroxypropyl methyl cellulose loaded with tetracycline hydrochloride: magnetic resonance imaging study
inferredcites →https://doi.org/10.1016/s0032-3861(97)00328-5openalex-snapshot
Simultaneous measurement of water and polymer concentration profiles during swelling of poly(ethylene oxide) using magnetic resonance imaging
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A review of polymer dissolution
inferredcites →https://doi.org/10.1016/s0168-3659(00)00245-5openalex-snapshot
Quantitative NMR imaging study of the mechanism of drug release from swelling hydroxypropylmethylcellulose tablets
inferredcites →https://doi.org/10.1016/s0168-3659(00)00366-7openalex-snapshot
Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate
inferredcites →https://doi.org/10.1016/s0168-3659(01)00556-9openalex-snapshot
Magnetic resonance imaging study of the swelling kinetics of hydroxypropylmethylcellulose (HPMC) in water
inferredcites →https://doi.org/10.1016/s0168-3659(97)00217-4openalex-snapshot
Complications in investigations of the swelling of hydrogel matrices due to the presence of trapped gas
inferredcites →https://doi.org/10.1016/s0168-3659(99)00260-6openalex-snapshot
NMR microscopy of the uptake, distribution and mobility of dissolution media in small, sub-millimetre drug delivery systems
inferredcites →https://doi.org/10.1016/s0376-7388(00)80471-8openalex-snapshot
Modelling of drug diffusion through swellable polymeric systems
inferredcites →https://doi.org/10.1016/s0730-725x(98)00021-6openalex-snapshot
Self-diffusion and molecular mobility in PVA-based dissolution-controlled systems for drug delivery
inferredcites →https://doi.org/10.1016/s1461-5347(00)00269-8openalex-snapshot
Swellable matrices for controlled drug delivery: gel-layer behaviour, mechanisms and optimal performance
inferredcites →https://doi.org/10.1016/s1461-5347(98)00008-xopenalex-snapshot
Magnetic resonance imaging of controlled release pharmaceutical dosage forms
inferredcites →https://doi.org/10.1021/bm015621eopenalex-snapshot
NMR Imaging of High-Amylose Starch Tablets. 1. Swelling and Water Uptake
inferredcites →https://doi.org/10.1021/bm025576qopenalex-snapshot
NMR Imaging of High-Amylose Starch Tablets. 2. Effect of Tablet Size
inferredcites →https://doi.org/10.1021/bm0503930openalex-snapshot
Imaging of High-Amylose Starch Tablets. 3. Initial Diffusion and Temperature Effects
inferredcites →https://doi.org/10.1021/jp044332sopenalex-snapshot
Molecular Information on the Dissolution of Polydisperse Polymers: Mixtures of Long and Short Poly(ethylene oxide)
inferredcites →https://doi.org/10.1021/jp069051uopenalex-snapshot
Plum-Pudding Gels as a Platform for Drug Delivery: Understanding the Effects of the Different Components on the Diffusion Behavior of Solutes
inferredcites →https://doi.org/10.1021/js970376jopenalex-snapshot
A Method for Quantifying differential expansion within Hydrating Hydrophilic Matrixes by Tracking Embedded Fluorescent Microspheres
inferredcites →https://doi.org/10.1021/ma00203a043openalex-snapshot
Hydrophobic microphase formation in surfactant solutions containing an amphiphilic graft copolymer
inferredcites →https://doi.org/10.1021/ma970076oopenalex-snapshot
Investigation of Hydrogel Formation from Hydroxypropylmethylcellulose (HPMC) by NMR Spectroscopy and NMR Imaging Techniques
inferredcites →https://doi.org/10.1021/mp200051eopenalex-snapshot
Polymer Swelling, Drug Mobilization and Drug Recrystallization in Hydrating Solid Dispersion Tablets Studied by Multinuclear NMR Microimaging and Spectroscopy
inferredcites →https://doi.org/10.1039/9781839164965openalex-snapshot
Nuclear Magnetic Resonance
inferredcites →https://doi.org/10.1039/c0sm00085jopenalex-snapshot
Lamellar phase separation in a centrifugal field. A method for measuring interbilayer forces
inferredcites →https://doi.org/10.1063/1.457962openalex-snapshot
Spatially resolved nuclear magnetic resonance study of polymer chains mobility during the swelling process
inferredcites →https://doi.org/10.1073/pnas.79.11.3523openalex-snapshot
NMR chemical shift imaging in three dimensions.
inferredcites →https://doi.org/10.1080/03639040802698810openalex-snapshot
Oral-based controlled release formulations using poly(acrylic acid) microgels
inferredcites →https://doi.org/10.1081/ddc-100000124openalex-snapshot
Polymeric Controlled Drug-Delivery Systems: Perspective Issues and Opportunities
inferredcites →https://doi.org/10.1517/17425247.2011.566554openalex-snapshot
Using quantitative magnetic resonance methods to understand better the gel-layer formation on polymer-matrix tablets
inferredcites →https://doi.org/10.5860/choice.33-2140openalex-snapshot
Principles of polymer chemistry

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Optimizing Extended-Release Hydrophilic Matrix Tablets: A Qbd Approach to Unveiling the Importance of Swelling and Erosion Dynamics in Early Development
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The Influence of High Drug Loading in Xanthan Tablets and Media with Different Physiological pH and Ionic Strength on Swelling and Release
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Effects of Added Surfactant on Swelling and Molecular Transport in Drug-Loaded Tablets Based on Hydrophobically Modified Poly(acrylic acid)
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Characterization of water state and distribution in fibre materials by low-field nuclear magnetic resonance
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Unveiling Swelling and Erosion Dynamics: Early Development Screening of Mirabegron Extended Release Tablets
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Release of a Poorly Soluble Drug from Hydrophobically Modified Poly (Acrylic Acid) in Simulated Intestinal Fluids
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