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Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors

https://doi.org/10.1021/ml200163b

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Using the Golden Triangle to optimize clearance and oral absorption

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Annual Reports in Medicinal Chemistry

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1

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Prediction of intestinal permeability

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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ADME Evaluation in Drug Discovery. 7. Prediction of Oral Absorption by Correlation and Classification

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Prediction of Drug Absorption Using Multivariate Statistics

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Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

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A Bioavailability Score

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Time-Related Differences in the Physical Property Profiles of Oral Drugs

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Rapid calculation of polar molecular surface area and its application to the prediction of transport phenomena. 1. Prediction of intestinal absorption

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The influence of drug-like concepts on decision-making in medicinal chemistry

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Epidemiology of HCV Infection

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In Silico Prediction, Molecular Docking and Dynamics Studies of Steroidal Alkaloids of Holarrhena pubescens Wall. ex G. Don to Guanylyl Cyclase C: Implications in Designing of Novel Antidiarrheal Therapeutic Strategies

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