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MS2 Viruslike Particles: A Robust, Semisynthetic Targeted Drug Delivery Platform

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Reduktionsprodukte der Arsanilsäure und ihrer Derivate Erste Mitteilung: über p‐Aminophenyl‐arsenoxyd
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Cell Targeting with Hybrid Qβ Virus‐Like Particles Displaying Epidermal Growth Factor
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A General Purification Procedure for Chemically Synthesized Oligoribonucleotides
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The three-dimensional structures of two complexes between recombinant MS2 capsids and RNA operator fragments reveal sequence-specific protein-RNA interactions
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Translational control of bacteriophage MS2 RNA cistrons by MS2 coat protein: Affinity and specificity of the interaction of MS2 coat protein with MS2 RNA
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Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis
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A Simple, RNA-Mediated Allosteric Switch Controls the Pathway to Formation of a T=3 Viral Capsid
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Single-Molecule Fluorescence Resonance Energy Transfer Assays Reveal Heterogeneous Folding Ensembles in a Simple RNA Stem–Loop
inferredcites →https://doi.org/10.1016/j.jmb.2009.11.018openalex-snapshot
Viral Genomic Single-Stranded RNA Directs the Pathway Toward a T=3 Capsid
inferredcites →https://doi.org/10.1016/j.jmb.2010.05.059openalex-snapshot
The Impact of Viral RNA on Assembly Pathway Selection
inferredcites →https://doi.org/10.1016/j.mvr.2008.02.004openalex-snapshot
Intracellular localization of lipoplexed siRNA in vascular endothelial cells of different mouse tissues
inferredcites →https://doi.org/10.1016/j.nano.2004.11.011openalex-snapshot
Delivery of antisense oligonucleotides to leukemia cells by RNA bacteriophage capsids
inferredcites →https://doi.org/10.1021/bc00035a013openalex-snapshot
Cell-Specific Delivery of Bacteriophage-Encapsidated Ricin A Chain
inferredcites →https://doi.org/10.1021/ja903857fopenalex-snapshot
Viral Capsid DNA Aptamer Conjugates as Multivalent Cell-Targeting Vehicles
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The First Targeted Delivery of siRNA in Humans via a Self-Assembling, Cyclodextrin Polymer-Based Nanoparticle: From Concept to Clinic
inferredcites →https://doi.org/10.1021/nl1002526openalex-snapshot
Hydrazone Ligation Strategy to Assemble Multifunctional Viral Nanoparticles for Cell Imaging and Tumor Targeting
inferredcites →https://doi.org/10.1021/nn1014769openalex-snapshot
Dual-Surface Modified Virus Capsids for Targeted Delivery of Photodynamic Agents to Cancer Cells
inferredcites →https://doi.org/10.1021/nn201397zopenalex-snapshot
Cell-Specific Delivery of Diverse Cargos by Bacteriophage MS2 Virus-like Particles
inferredcites →https://doi.org/10.1038/303543a0openalex-snapshot
Pb(II)-catalysed cleavage of the sugar–phosphate backbone of yeast tRNAPhe—implications for lead toxicity and self-splicing RNA
inferredcites →https://doi.org/10.1038/345036a0openalex-snapshot
The three-dimensional structure of the bacterial virus MS2
inferredcites →https://doi.org/10.1038/371623a0openalex-snapshot
Crystal structure of an RNA bacteriophage coat protein–operator complex
inferredcites →https://doi.org/10.1038/372333a0openalex-snapshot
Gene inhibition using antisense oligodeoxynucleotides
inferredcites →https://doi.org/10.1038/nbt1051openalex-snapshot
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
inferredcites →https://doi.org/10.1038/nbt1223openalex-snapshot
Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras
inferredcites →https://doi.org/10.1038/nprot.2010.103openalex-snapshot
Intravital imaging of embryonic and tumor neovasculature using viral nanoparticles
inferredcites →https://doi.org/10.1038/nrd3141openalex-snapshot
Aptamers as therapeutics
inferredcites →https://doi.org/10.1073/pnas.1204357109openalex-snapshot
Evidence that viral RNAs have evolved for efficient, two-stage packaging
inferredcites →https://doi.org/10.1093/nar/23.13.2512openalex-snapshot
Probing sequence-specific RNA recognition by the bacteriophage MS2 coat protien
inferredcites →https://doi.org/10.1099/0022-1317-74-4-541openalex-snapshot
Multiple presentation of foreign peptides on the surface of an RNA-free spherical bacteriophage capsid
inferredcites →https://doi.org/10.1101/sqb.1962.027.001.005openalex-snapshot
Physical Principles in the Construction of Regular Viruses
inferredcites →https://doi.org/10.1103/physreve.81.031908openalex-snapshot
All-atom normal-mode analysis reveals an RNA-induced allostery in a bacteriophage coat protein
inferredcites →https://doi.org/10.1111/j.1742-4658.2012.08512.xopenalex-snapshot
Development of a microRNA delivery system based on bacteriophage MS2 virus‐like particles
inferredcites →https://doi.org/10.1126/science.1095833openalex-snapshot
Drug Delivery Systems: Entering the Mainstream
inferredcites →https://doi.org/10.1128/jvi.80.1.172-180.2006openalex-snapshot
Characterization of Early Steps in the Poliovirus Infection Process: Receptor-Decorated Liposomes Induce Conversion of the Virus to Membrane-Anchored Entry-Intermediate Particles
inferredcites →https://doi.org/10.1152/physrev.1925.5.1.63openalex-snapshot
THE PHARMACOLOGY OF ARSPHENAMINE (SALVARSAN) AND RELATED ARSENICALS
inferredcites →https://doi.org/10.1158/0008-5472.can-08-2428openalex-snapshot
Atu027, a Liposomal Small Interfering RNA Formulation Targeting Protein Kinase N3, Inhibits Cancer Progression
inferredcites →https://doi.org/10.1159/000067930openalex-snapshot
RNA Bacteriophage Capsid-Mediated Drug Delivery and Epitope Presentation
inferredcites →https://doi.org/10.1371/journal.ppat.1000417openalex-snapshot
Endothelial Targeting of Cowpea Mosaic Virus (CPMV) via Surface Vimentin
inferredcites →https://doi.org/10.1515/bc-2011-256openalex-snapshot
Dye selection for live cell imaging of intact siRNA
inferredcites →https://doi.org/10.2134/jeq2008.0451openalex-snapshot
Modifying the Surface Charge of Pathogen‐Sized Microspheres for Studying Pathogen Transport in Groundwater
inferredcites →https://doi.org/10.5414/cpp50076openalex-snapshot
Phase I clinical development of Atu027, a siRNA formulation targeting PKN3 in patients with advanced solid tumors

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Methods for Preparation of MS2 Phage-Like Particles and Their Utilization as Process Control Viruses in RT-PCR and qRT-PCR Detection of RNA Viruses From Food Matrices and Clinical Specimens
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Purification of human papillomavirus-like particles expressed in silkworm using a Bombyx mori nucleopolyhedrovirus bacmid expression system
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Viruses as biomaterials
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Virus Like Particles: A Self-Assembled Toolbox for Cancer Therapy
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Cryo-EM reveals infection steps of single-stranded RNA bacteriophages
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Nanoparticles applied to cancer immunoregulation
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Virus-inspired strategies for cancer therapy
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Poly(I:C) and CpG improve the assembly of foot-and-mouth disease virus-like particles and immune response in mice
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Virus-Like Particles: From Fundamental Concepts to Cutting-Edge Applications — A Comprehensive Review of Production, Engineering, and Clinical Translation
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Experimental Evaluation of Coevolution in a Self-Assembling Particle
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The Protein Corona Does Not Influence Receptor-Mediated Targeting of Virus-like Particles
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Protein Cages: From Fundamentals to Advanced Applications
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Disassembly of Virus-Like Particles and the Stabilizing Role of the Nucleic Acid Cargo
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A Selection for Assembly Reveals That a Single Amino Acid Mutant of the Bacteriophage MS2 Coat Protein Forms a Smaller Virus-like Particle
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Deciphering the Thermal Stability of Bacteriophage MS2-Derived Virus-like Particle and Its Engineered Variant
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Synthetic Rewiring of Virus-like Particles via Circular Permutation Enables Modular Peptide Display and Protein Encapsulation
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Lysine Addressability and Mammalian Cell Interactions of Bacteriophage λ Procapsids
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Encapsidated Atom-Transfer Radical Polymerization in Qβ Virus-like Nanoparticles
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Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles
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Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle
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One-plasmid double-expression His-tag system for rapid production and easy purification of MS2 phage-like particles
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Chimeric virus-like particles (VLPs) designed from shrimp nodavirus (MrNV) capsid protein specifically target EGFR-positive human colorectal cancer cells
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Programmable polymorphism of a virus-like particle
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Running rings around protein cages: a case study of artificial TRAP cages
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Functionalization of protein-based nanocages for drug delivery applications
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Design of virus-based nanomaterials for medicine, biotechnology, and energy
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Delivery of siRNA therapeutics using cowpea chlorotic mottle virus-like particles
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Using FRET to measure the time it takes for a cell to destroy a virus
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Biomedical applications of dendritic fibrous nanosilica (DFNS): recent progress and challenges
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Effect of coat-protein concentration on the self-assembly of bacteriophage MS2 capsids around RNA
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Virus-like particles based on plant viruses and bacteriophages: emerging strategies for the delivery of nucleic acid therapeutics
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Oncogene dependency and the potential of targeted RNAi-based anti-cancer therapy
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Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release
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Rewriting nature’s assembly manual for a ssRNA virus
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New generation of viral nanoparticles for targeted drug delivery in cancer therapy
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Virus-like particle-based nanocarriers as an emerging platform for drug delivery
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Mechanisms of cellular and humoral immunity through the lens of VLP-based vaccines
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Virus-Like Particle: Evolving Meanings in Different Disciplines
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Functional RNAs: combined assembly and packaging in VLPs
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Antibody-targeted chromatin enables effective intracellular delivery and functionality of CRISPR/Cas9 expression plasmids
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Engineered Riboswitch Nano-carriers as a Possible Disease-Modifying Treatment for Metabolic Disorders
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Globoside is an essential intracellular factor required for parvovirus B19 endosomal escape in erythroid progenitor cells
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Liquid-Liquid Phase Separation Enables Highly Selective Viral Genome Packaging
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Phage-Based Applications in Synthetic Biology
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Virus-Based Nanoparticles as Versatile Nanomachines
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The True Story and Advantages of RNA Phage Capsids as Nanotools
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Display of single-chain variable fragments on bacteriophage MS2 virus-like particles
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Virus-like particles: preparation, immunogenicity and their roles as nanovaccines and drug nanocarriers
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Phage-based delivery systems: engineering, applications, and challenges in nanomedicines
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Protein-based vehicles for biomimetic RNAi delivery
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Immunotherapy and Vaccines
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Progress in mRNA delivery systems based on virus-like particles
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How much genetic information in RNA form can be protected by a CCMV virus-like particle?
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Progress and perspective of inorganic nanoparticle-based siRNA delivery systems
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Quantitative functionalization of biosynthetic caged protein materials
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Bakteriofago vB_EcoS_NBD2 kilmės nanovamzdelių pritaikymas baltyminių fragmentų eksponavimui
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Modulating microRNAs in cancer: Next-generation therapies
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Genetically engineered nanocarriers for drug delivery
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Chemically Activatable Viral Capsid Functionalized for Cancer Targeting
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Site-Specific Generation of Protein-Protein Conjugates Using Native Amino Acids
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Biologically-Derived Nanomaterials for Targeted Therapeutic Delivery to the Brain
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Development of immune-modulatory RNAS to regulate RIG-I-like receptors mediated antiviral immune response for therapy and vaccination
inferred← citeshttps://doi.org/10.3389/fchem.2021.613209openalex-snapshot
Viral Mimicry as a Design Template for Nucleic Acid Nanocarriers
inferred← citeshttps://doi.org/10.3389/fcimb.2022.1079926openalex-snapshot
Virus-like particle – mediated delivery of the RIG-I agonist M8 induces a type I interferon response and protects cells against viral infection
inferred← citeshttps://doi.org/10.3389/fcimb.2022.997875openalex-snapshot
How promising are HIV-1-based virus-like particles for medical applications
inferred← citeshttps://doi.org/10.3389/fmolb.2022.967877openalex-snapshot
The diversity of protein-protein interaction interfaces within T=3 icosahedral viral capsids
inferred← citeshttps://doi.org/10.3389/fphys.2017.00399openalex-snapshot
Viral Delivery of dsRNA for Control of Insect Agricultural Pests and Vectors of Human Disease: Prospects and Challenges
inferred← citeshttps://doi.org/10.3389/fvets.2024.1460973openalex-snapshot
Cell-penetrating peptides TAT and 8R functionalize P22 virus-like particles to enhance tissue distribution and retention in vivo
inferred← citeshttps://doi.org/10.3390/cells13151254openalex-snapshot
Globoside Is an Essential Intracellular Factor Required for Parvovirus B19 Endosomal Escape
inferred← citeshttps://doi.org/10.3390/genes9070370openalex-snapshot
Bioengineering Strategies for Protein-Based Nanoparticles
inferred← citeshttps://doi.org/10.3390/ijms241612963openalex-snapshot
Virus-like Particle (VLP) Vaccines for Cancer Immunotherapy
inferred← citeshttps://doi.org/10.3390/ijms242317029openalex-snapshot
RNA and Single-Stranded DNA Phages: Unveiling the Promise from the Underexplored World of Viruses
inferred← citeshttps://doi.org/10.3390/ijms25126699openalex-snapshot
Tailored Viral-like Particles as Drivers of Medical Breakthroughs
inferred← citeshttps://doi.org/10.3390/life11040334openalex-snapshot
In Vitro Assembly of Virus-Like Particles and Their Applications
inferred← citeshttps://doi.org/10.3390/molecules23092311openalex-snapshot
Application of Plant Viruses as a Biotemplate for Nanomaterial Fabrication
inferred← citeshttps://doi.org/10.3390/pharmaceutics17101305openalex-snapshot
RNA Therapeutics: Delivery Problems and Solutions—A Review
inferred← citeshttps://doi.org/10.3390/v12121463openalex-snapshot
The VP1u of Human Parvovirus B19: A Multifunctional Capsid Protein with Biotechnological Applications
inferred← citeshttps://doi.org/10.3390/v8100265openalex-snapshot
The VP1u Receptor Restricts Parvovirus B19 Uptake to Permissive Erythroid Cells
inferred← citeshttps://doi.org/10.3390/vaccines5010006openalex-snapshot
Harnessing Nanoparticles for Immunomodulation and Vaccines
inferred← citeshttps://doi.org/10.3390/vaccines6030037openalex-snapshot
Interaction of Viral Capsid-Derived Virus-Like Particles (VLPs) with the Innate Immune System
inferred← citeshttps://doi.org/10.3390/vaccines9101129openalex-snapshot
Nanotechnology Interventions in the Management of COVID-19: Prevention, Diagnosis and Virus-Like Particle Vaccines
inferred← citeshttps://doi.org/10.3791/57020openalex-snapshot
Surface Functionalization of Hepatitis E Virus Nanoparticles Using Chemical Conjugation Methods
inferred← citeshttps://doi.org/10.3934/bioeng.2017.2.198openalex-snapshot
Drug delivery from engineered organisms and nanocarriers as monitored by multimodal imaging technologies
inferred← citeshttps://doi.org/10.47749/t/unicamp.2019.1094106openalex-snapshot
Desenvolvimento de nanocompósitos de óxido de grafeno decorado com nanopartículas de sílica mesoporosa como nanocarreadores de fármacos
inferred← citeshttps://doi.org/10.70675/fe631d3ezac2bz4ea4za9a7z1abc064e4d76openalex-snapshot
Recouvrement et modification de nanoparticules afin d’optimiser leurs propriétés physico-chimiques pour des applications pharmaceutiques
inferred← citeshttps://doi.org/10.71150/jm.2510016openalex-snapshot
Armored RNA technology as a clinical diagnostics tool for future pandemic preparedness
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