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Terpenoids: Opportunities for Biosynthesis of Natural Product Drugs Using Engineered Microorganisms

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inferredcites →https://doi.org/10.1002/(sici)1097-0290(19980420)58:2/3<306::aid-bit29>3.0.co;2-8openalex-snapshot

Production of lycopene by the food yeast, Candida utilis that does not naturally synthesize carotenoid

inferredcites →https://doi.org/10.1002/(sici)1097-0290(19990120)62:2<235::aid-bit14>3.0.co;2-uopenalex-snapshot

Engineered isoprenoid pathway enhances astaxanthin production inEscherichia coli

inferredcites →https://doi.org/10.1002/1097-0290(20000220)72:4<408::aid-bit1003>3.0.co;2-hopenalex-snapshot

Metabolic engineering of the nonmevalonate isopentenyl diphosphate synthesis pathway inEscherichia coli enhances lycopene production

inferredcites →https://doi.org/10.1002/9783527609949openalex-snapshot

Terpenes

inferredcites →https://doi.org/10.1002/adsc.200505062openalex-snapshot

Current and Emerging Approaches for Natural Product Biosynthesis in Microbial Cells

inferredcites →https://doi.org/10.1002/bit.10037openalex-snapshot

The in vivo synthesis of plant sesquiterpenes by Escherichia coli

inferredcites →https://doi.org/10.1002/bit.20128openalex-snapshot

Mono and diterpene production in Escherichia coli

inferredcites →https://doi.org/10.1002/bit.20539openalex-snapshot

Identification of genes affecting lycopene accumulation in Escherichia coli using a shot‐gun method

inferredcites →https://doi.org/10.1002/bit.20694openalex-snapshot

Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae

inferredcites →https://doi.org/10.1002/bit.20912openalex-snapshot

Enhanced lycopene production in Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate

inferredcites →https://doi.org/10.1002/bit.21017openalex-snapshot

High‐level production of amorpha‐4,11‐diene in a two‐phase partitioning bioreactor of metabolically engineered Escherichia coli

inferredcites →https://doi.org/10.1002/bit.21581openalex-snapshot

Production of plant sesquiterpenes in Saccharomyces cerevisiae : Effect of ERG9 repression on sesquiterpene biosynthesis

inferredcites →https://doi.org/10.1002/cbdv.200590038openalex-snapshot

Biotransformation of Terpenoids by Mammals, Microorganisms, and Plant-Cultured Cells

inferredcites →https://doi.org/10.1002/cbic.200300783openalex-snapshot

Exploring Recombinant Flavonoid Biosynthesis in Metabolically Engineered Escherichia coli

inferredcites →https://doi.org/10.1002/chin.200447248openalex-snapshot

Occurrence, Biological Activity and Synthesis of Drimane Sesquiterpenoids

inferredcites →https://doi.org/10.1002/ejoc.200400634openalex-snapshot

Total Synthesis of 3‐Hydroxydrimanes Mediated by Titanocene( III ) – Evaluation of Their Antifeedant Activity

inferredcites →https://doi.org/10.1006/jmbi.2001.5341openalex-snapshot

Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids

inferredcites →https://doi.org/10.1006/mben.2001.0211openalex-snapshot

Mathematical Modeling of Plant Metabolic Pathways

inferredcites →https://doi.org/10.1007/3-540-44964-7_1openalex-snapshot

The Natural Functions of Secondary Metabolites

inferredcites →https://doi.org/10.1007/978-3-642-48346-2openalex-snapshot

Bioorganic Marine Chemistry

inferredcites →https://doi.org/10.1007/b13538openalex-snapshot

Paclitaxel Production by Plant-Cell-Culture Technology

inferredcites →https://doi.org/10.1007/b136410openalex-snapshot

Microbial Isoprenoid Production: An Example of Green Chemistry through Metabolic Engineering

inferredcites →https://doi.org/10.1007/bf01195344openalex-snapshot

Sequence-dependent cytotoxic effects due to combinations of cisplatin and the antimicrotubule agents taxol and vincristine

inferredcites →https://doi.org/10.1007/bf02059809openalex-snapshot

Higher plant terpenoids: A phytocentric overview of their ecological roles

inferredcites →https://doi.org/10.1007/s00005-007-0039-1openalex-snapshot

Terpenes: substances useful in human healthcare

inferredcites →https://doi.org/10.1007/s00204-006-0072-6openalex-snapshot

Dual activity of triterpenoids: apoptotic versus antidifferentiation effects

inferredcites →https://doi.org/10.1007/s00253-006-0357-yopenalex-snapshot

Characterization of lycopene-overproducing E. coli strains in high cell density fermentations

inferredcites →https://doi.org/10.1007/s00253-006-0452-0openalex-snapshot

Artemisinin: current state and perspectives for biotechnological production of an antimalarial drug

inferredcites →https://doi.org/10.1007/s00253-006-0593-1openalex-snapshot

Biosynthesis and engineering of isoprenoid small molecules

inferredcites →https://doi.org/10.1007/s00253-006-0623-zopenalex-snapshot

Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis

inferredcites →https://doi.org/10.1007/s00253-007-1206-3openalex-snapshot

An update on microbial carotenoid production: application of recent metabolic engineering tools

inferredcites →https://doi.org/10.1007/s002530051032openalex-snapshot

Production of zeaxanthin in Escherichia coli transformed with different carotenogenic plasmids

inferredcites →https://doi.org/10.1007/s002530051632openalex-snapshot

Metabolic engineering of carotenoid accumulation in Escherichia coli by modulation of the isoprenoid precursor pool with expression of deoxyxylulose phosphate synthase

inferredcites →https://doi.org/10.1007/s002800050957openalex-snapshot

Structure-activity profiles of eleutherobin analogs and their cross-resistance in Taxol-resistant cell lines

inferredcites →https://doi.org/10.1007/s00436-002-0768-3openalex-snapshot

Natural products as antiparasitic drugs

inferredcites →https://doi.org/10.1007/s10529-006-0015-6openalex-snapshot

Production of the Artemisinin Precursor Amorpha-4,11-diene by Engineered Saccharomyces cerevisiae

inferredcites →https://doi.org/10.1007/s11101-005-5464-3openalex-snapshot

Terpenoids from Marine Organisms: Unique Structures and their Pharmacological Potential

inferredcites →https://doi.org/10.1016/0010-7824(85)90027-7openalex-snapshot

(−)-Gossypol: An active male antifertility agent

inferredcites →https://doi.org/10.1016/0022-0981(92)90237-5openalex-snapshot

Activation of chemical defenses in the tropical green algae Halimeda spp.

inferredcites →https://doi.org/10.1016/0167-7799(93)90099-uopenalex-snapshot

Metabolic engineering — methodologies and future prospects

inferredcites →https://doi.org/10.1016/0167-7799(94)90120-1openalex-snapshot

Taxol: The chemistry and structure-activity relationships of a novel anticancer agent

inferredcites →https://doi.org/10.1016/0304-3894(92)85068-copenalex-snapshot

Chemical substitution for 1,1,1-trichloroethane and methanol in an industrial cleaning operation

inferredcites →https://doi.org/10.1016/0378-5173(95)04108-7openalex-snapshot

Modes of action of terpene penetration enhancers in human skin; Differential scanning calorimetry, small-angle X-ray diffraction and enhancer uptake studies

inferredcites →https://doi.org/10.1016/j.addr.2003.10.025openalex-snapshot

Penetration enhancers

inferredcites →https://doi.org/10.1016/j.bioorg.2004.08.004openalex-snapshot

1-Deoxy-d-xylulose 5-phosphate reductoisomerase: an overview

inferredcites →https://doi.org/10.1016/j.biotechadv.2005.08.004openalex-snapshot

Biotransformation of terpenes

inferredcites →https://doi.org/10.1016/j.cbpa.2007.08.012openalex-snapshot

Natural products as a screening resource

inferredcites →https://doi.org/10.1016/j.chembiol.2007.01.006openalex-snapshot

Genome-Wide High-Throughput Mining of Natural-Product Biosynthetic Gene Clusters by Phage Display

inferredcites →https://doi.org/10.1016/j.copbio.2004.09.002openalex-snapshot

Natural products as a hunting ground for combinatorial chemistry

inferredcites →https://doi.org/10.1016/j.ejphar.2004.11.012openalex-snapshot

Topical antiinflammatory effects of the ether extract from Protium kleinii and α-amyrin pentacyclic triterpene

inferredcites →https://doi.org/10.1016/j.febslet.2005.05.047openalex-snapshot

fldA is an essential gene required in the 2‐C‐methyl‐ D ‐erythritol 4‐phosphate pathway for isoprenoid biosynthesis

inferredcites →https://doi.org/10.1016/j.foodchem.2005.01.003openalex-snapshot

Carvone: Why and how should one bother to produce this terpene

inferredcites →https://doi.org/10.1016/j.ijpharm.2003.09.026openalex-snapshot

Development of a perillyl alcohol topical cream formulation

inferredcites →https://doi.org/10.1016/j.jconrel.2003.11.022openalex-snapshot

Transdermal delivery of zidovudine: effect of terpenes and their mechanism of action

inferredcites →https://doi.org/10.1016/j.jmb.2004.10.030openalex-snapshot

The Crystal Structure of E.coli 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase in a Ternary Complex with the Antimalarial Compound Fosmidomycin and NADPH Reveals a Tight-binding Closed Enzyme Conformation

inferredcites →https://doi.org/10.1016/j.jmb.2006.10.092openalex-snapshot

Crystal Structures of Human IPP Isomerase: New Insights into the Catalytic Mechanism

inferredcites →https://doi.org/10.1016/j.pbi.2005.03.003openalex-snapshot

The use of genetics to dissect plant secondary pathways

inferredcites →https://doi.org/10.1016/j.pbi.2006.03.003openalex-snapshot

Integrative analysis of metabolic networks: from peaks to flux models?

inferredcites →https://doi.org/10.1016/j.pbi.2006.03.004openalex-snapshot

Biosynthetic diversity in plant triterpene cyclization

inferredcites →https://doi.org/10.1016/j.phytochem.2006.10.019openalex-snapshot

Administering cultured Taxus cells with early precursors reveals bifurcations in the taxoid biosynthetic pathway

inferredcites →https://doi.org/10.1016/j.tibtech.2007.01.003openalex-snapshot

Expanding the metabolic engineering toolbox: more options to engineer cells

inferredcites →https://doi.org/10.1016/j.tibtech.2007.07.006openalex-snapshot

Engineering microbial cell factories for biosynthesis of isoprenoid molecules: beyond lycopene

inferredcites →https://doi.org/10.1016/j.ymben.2004.12.003openalex-snapshot

Identifying gene targets for the metabolic engineering of lycopene biosynthesis in Escherichia coli

inferredcites →https://doi.org/10.1016/j.ymben.2005.08.005openalex-snapshot

Chromosomal promoter replacement of the isoprenoid pathway for enhancing carotenoid production in E. coli

inferredcites →https://doi.org/10.1016/j.ymben.2006.10.005openalex-snapshot

Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae for high-level production of isoprenoids

inferredcites →https://doi.org/10.1016/j.ymben.2006.11.002openalex-snapshot

Balancing a heterologous mevalonate pathway for improved isoprenoid production in Escherichia coli

inferredcites →https://doi.org/10.1016/j.ymben.2007.03.003openalex-snapshot

Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli

inferredcites →https://doi.org/10.1016/s0002-9343(01)00995-0openalex-snapshot

Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer

inferredcites →https://doi.org/10.1016/s0003-9861(03)00233-9openalex-snapshot

Metabolic cross talk between cytosolic and plastidial pathways of isoprenoid biosynthesis: unidirectional transport of intermediates across the chloroplast envelope membrane

inferredcites →https://doi.org/10.1016/s0014-2999(02)02856-xopenalex-snapshot

(−)-Linalool produces antinociception in two experimental models of pain

inferredcites →https://doi.org/10.1016/s0014-5793(99)00360-9openalex-snapshot

Expression of prokaryotic 1‐deoxy‐ d ‐xylulose‐5‐phosphatases in Escherichia coli increases carotenoid and ubiquinone biosynthesis

inferredcites →https://doi.org/10.1016/s0021-9258(18)96085-0openalex-snapshot

A Long Chain Terpenyl Pyrophosphate Synthetase from Micrococcus lysodeikticus

inferredcites →https://doi.org/10.1016/s0021-9258(19)47425-5openalex-snapshot

Selective inhibition of isoprenylation of 21-26-kDa proteins by the anticarcinogen d-limonene and its metabolites.

inferredcites →https://doi.org/10.1016/s0022-474x(02)00020-6openalex-snapshot

Fumigation toxicity of monoterpenoids to several stored product insects

inferredcites →https://doi.org/10.1016/s0024-3205(01)01396-0openalex-snapshot

Caulerpenyne from Caulerpa taxifolia has an antiproliferative activity on tumor cell line SK-N-SH and modifies the microtubule network

inferredcites →https://doi.org/10.1016/s0031-9422(03)00204-8openalex-snapshot

Monoterpene biosynthesis pathway construction in Escherichia coli

inferredcites →https://doi.org/10.1016/s0031-9422(03)00225-5openalex-snapshot

Cardioactive and antibacterial terpenoids from some Salvia species

inferredcites →https://doi.org/10.1016/s0040-4020(01)00692-5openalex-snapshot

Rapid wound-activated transformation of the green algal defensive metabolite caulerpenyne

inferredcites →https://doi.org/10.1016/s0040-4020(98)00818-7openalex-snapshot

Antimalarial activity of kalihinol A and new relative diterpenoids from the Okinawan sponge, Acanthella sp.

inferredcites →https://doi.org/10.1016/s0163-7258(01)00140-1openalex-snapshot

Artemisinin and its derivatives: an important new class of antimalarial agents

inferredcites →https://doi.org/10.1016/s0165-6147(02)02098-9openalex-snapshot

Transcription factors: tools to engineer the production of pharmacologically active plant metabolites

inferredcites →https://doi.org/10.1016/s0166-3542(99)00036-4openalex-snapshot

Antiviral properties of isoborneol, a potent inhibitor of herpes simplex virus type 1

inferredcites →https://doi.org/10.1016/s0167-4501(06)80011-7openalex-snapshot

Biotechnological production of terpenoid flavour and fragrance compounds in tailored bioprocesses

inferredcites →https://doi.org/10.1016/s0168-1656(97)00151-xopenalex-snapshot

Synthesis of atypical cyclic and acyclic hydroxy carotenoids in Escherichia coli transformants

inferredcites →https://doi.org/10.1016/s0278-5846(00)00112-3openalex-snapshot

Neurotoxic effects of caulerpenyne

inferredcites →https://doi.org/10.1016/s0305-1978(01)00045-xopenalex-snapshot

Chemical information transfer between plants:

inferredcites →https://doi.org/10.1016/s0306-4522(01)00365-7openalex-snapshot

Caulerpenyne, a toxin from the seaweed Caulerpa taxifolia, depresses afterhyperpolarization in invertebrate neurons

inferredcites →https://doi.org/10.1016/s0928-8244(98)00021-2openalex-snapshot

Antimycobacterial activity of chemically defined natural substances from the Caribbean flora in Guadeloupe

inferredcites →https://doi.org/10.1016/s0959-440x(98)80088-2openalex-snapshot

Managing and manipulating carbocations in biology: terpenoid cyclase structure and mechanism

inferredcites →https://doi.org/10.1016/s0960-894x(02)00350-5openalex-snapshot

Antimalarial compounds from Parinari capensis

inferredcites →https://doi.org/10.1016/s0968-0896(01)00072-4openalex-snapshot

Engineering Escherichia coli for the synthesis of taxadiene, a key intermediate in the biosynthesis of taxol

inferredcites →https://doi.org/10.1016/s1074-5521(03)00103-0openalex-snapshot

Biosynthesis of Structurally Novel Carotenoids in Escherichia coli

inferredcites →https://doi.org/10.1016/s1096-7176(03)00028-4openalex-snapshot

Engineering central metabolism in crop species:

inferredcites →https://doi.org/10.1016/s1369-5266(02)00251-0openalex-snapshot

The formation and function of plant volatiles: perfumes for pollinator attraction and defense

inferredcites →https://doi.org/10.1016/s1388-1981(00)00136-0openalex-snapshot

Isoprenyl diphosphate synthases

inferredcites →https://doi.org/10.1017/s0025315400029180openalex-snapshot

The Influence of The Introduced Tropical Alga Caulerpa Taxifolia, on the Biodiversity of the Mediterranean Marine Biota

inferredcites →https://doi.org/10.1021/bi0487241openalex-snapshot

Kinetic Analysis of Escherichia coli 2-C-Methyl- d -erythritol-4-phosphate Cytidyltransferase, Wild Type and Mutants, Reveals Roles of Active Site Amino Acids

inferredcites →https://doi.org/10.1021/bp000124fopenalex-snapshot

Directed Evolution of Metabolically Engineered Escherichia coli for Carotenoid Production

inferredcites →https://doi.org/10.1021/bp000137topenalex-snapshot

Precursor Balancing for Metabolic Engineering of Lycopene Production in Escherichia coli

inferredcites →https://doi.org/10.1021/bp050124lopenalex-snapshot

Enhanced Lycopene Productivity by Manipulation of Carbon Flow to Isopentenyl Diphosphate in Escherichia coli

inferredcites →https://doi.org/10.1021/cen-v072n034.p013openalex-snapshot

Self-Incrimination Remains Major Problem With Environmental Audits

inferredcites →https://doi.org/10.1021/cr9600464openalex-snapshot

Enzymatic Aspects of Isoprenoid Chain Elongation

inferredcites →https://doi.org/10.1021/ja029171popenalex-snapshot

Structure and Mechanism of Action of Isopentenylpyrophosphate-Dimethylallylpyrophosphate Isomerase

inferredcites →https://doi.org/10.1021/ja0471727openalex-snapshot

IspH Protein ofEscherichiacoli: Studies on Iron−Sulfur Cluster Implementation and Catalysis

inferredcites →https://doi.org/10.1021/jf0495340openalex-snapshot

Antibacterial Activities of Plant Essential Oils and Their Components against Escherichia coli O157:H7 and Salmonella enterica in Apple Juice

inferredcites →https://doi.org/10.1021/jf050702dopenalex-snapshot

Occurrence of (+)- and (−)-Gossypol in Wild Species of Cotton and in Gossypium hirsutum Var. marie-galante (Watt) Hutchinson

inferredcites →https://doi.org/10.1021/jf9602176openalex-snapshot

A Nematode Larval Motility Inhibition Assay for Screening Plant Extracts and Natural Products

inferredcites →https://doi.org/10.1021/jm0010724openalex-snapshot

Inhibition of Heme Detoxification Processes Underlies the Antimalarial Activity of Terpene Isonitrile Compounds from Marine Sponges

inferredcites →https://doi.org/10.1021/jo00303a030openalex-snapshot

New anti-inflammatory pseudopterosins from the marine octocoral Pseudopterogorgia elisabethae

inferredcites →https://doi.org/10.1021/jo00376a016openalex-snapshot

The pseudopterosins: a new class of antiinflammatory and analgesic diterpene pentosides from the marine sea whip Pseudopterogorgia elisabethae (Octocorallia)

inferredcites →https://doi.org/10.1021/np010032fopenalex-snapshot

Leishmanicidal, Antiplasmodial, and Cytotoxic Activity of Novel Diterpenoid 1,2-Quinones from Perovskia abrotanoides : New Source of Tanshinones

inferredcites →https://doi.org/10.1021/np010445gopenalex-snapshot

Monoterpene Hydroperoxides with Trypanocidal Activity from Chenopodium ambrosioides

inferredcites →https://doi.org/10.1021/np040031yopenalex-snapshot

Marine Natural Products and Related Compounds in Clinical and Advanced Preclinical Trials

inferredcites →https://doi.org/10.1021/np049802oopenalex-snapshot

New Pseudopterosin and seco-Pseudopterosin Diterpene Glycosides from Two Colombian Isolates of Pseudopterogorgia elisabethae and Their Diverse Biological Activities

inferredcites →https://doi.org/10.1021/np0504659openalex-snapshot

Microbial and Enzymatic Transformations of Flavonoids

inferredcites →https://doi.org/10.1021/np068054vopenalex-snapshot

Natural Products as Sources of New Drugs over the Last 25 Years

inferredcites →https://doi.org/10.1021/np50066a001openalex-snapshot

Why Are Secondary Metabolites (Natural Products) Biosynthesized?

inferredcites →https://doi.org/10.1021/ol034231xopenalex-snapshot

Metabolic Engineering to Produce Sesquiterpenes in Yeast

inferredcites →https://doi.org/10.1023/a:1005547827380openalex-snapshot

Metabolic engineering of the terpenoid biosynthetic pathway of Escherichia coli for production of the carotenoids β-carotene and zeaxanthin

inferredcites →https://doi.org/10.1023/a:1014549500678openalex-snapshot

The Introduced Green Alga Caulerpa Taxifolia Continues to Spread in the Mediterranean

inferredcites →https://doi.org/10.1023/a:1015813803205openalex-snapshot

Terpenes and the Lipid–Protein–Partitioning Theory of Skin Penetration Enhancement

inferredcites →https://doi.org/10.1038/343425a0openalex-snapshot

Regulation of the mevalonate pathway

inferredcites →https://doi.org/10.1038/75398openalex-snapshot

Improving lycopene production in Escherichia coli by engineering metabolic control

inferredcites →https://doi.org/10.1038/81132openalex-snapshot

Transgenic plants as factories for biopharmaceuticals

inferredcites →https://doi.org/10.1038/nature03194openalex-snapshot

Lessons from natural molecules

inferredcites →https://doi.org/10.1038/nature04640openalex-snapshot

Production of the antimalarial drug precursor artemisinic acid in engineered yeast

inferredcites →https://doi.org/10.1038/nbt0407-428openalex-snapshot

Antibiotic production from the ground up

inferredcites →https://doi.org/10.1038/nbt1016openalex-snapshot

Exploiting biological complexity for strain improvement through systems biology

inferredcites →https://doi.org/10.1038/nbt1083openalex-snapshot

Construction of lycopene-overproducing E. coli strains by combining systematic and combinatorial gene knockout targets

inferredcites →https://doi.org/10.1038/nbt1226openalex-snapshot

Combinatorial engineering of intergenic regions in operons tunes expression of multiple genes

inferredcites →https://doi.org/10.1038/nbt1312openalex-snapshot

Enrichment of tomato flavor by diversion of the early plastidial terpenoid pathway

inferredcites →https://doi.org/10.1038/nbt1333openalex-snapshot

A diverse family of thermostable cytochrome P450s created by recombination of stabilizing fragments

inferredcites →https://doi.org/10.1038/nbt833openalex-snapshot

Engineering a mevalonate pathway in Escherichia coli for production of terpenoids

inferredcites →https://doi.org/10.1038/nchembio.2007.1openalex-snapshot

Modern synthetic efforts toward biologically active terpenes

inferredcites →https://doi.org/10.1038/nchembio.2007.5openalex-snapshot

The function of terpene natural products in the natural world

inferredcites →https://doi.org/10.1038/nchembio.2007.7openalex-snapshot

Mining and engineering natural-product biosynthetic pathways

inferredcites →https://doi.org/10.1038/nchembio.2007.8openalex-snapshot

Production and engineering of terpenoids in plant cell culture

inferredcites →https://doi.org/10.1038/nchembio0707-360openalex-snapshot

Revisiting the ancient concept of botanical therapeutics

inferredcites →https://doi.org/10.1038/nchembio0907-531openalex-snapshot

Natural product biosynthesis moves in vitro

inferredcites →https://doi.org/10.1038/nchembio836openalex-snapshot

Production of isoprenoid pharmaceuticals by engineered microbes

inferredcites →https://doi.org/10.1038/nchembio875openalex-snapshot

Engineering Escherichia coli for production of functionalized terpenoids using plant P450s

inferredcites →https://doi.org/10.1038/nmeth0607-470aopenalex-snapshot

Mining for natural products

inferredcites →https://doi.org/10.1038/nrd1256openalex-snapshot

Metabolic engineering for drug discovery and development

inferredcites →https://doi.org/10.1038/nrd1657openalex-snapshot

The evolving role of natural products in drug discovery

inferredcites →https://doi.org/10.1038/sj.bjp.0707306openalex-snapshot

In silicopharmacology for drug discovery: applications to targets and beyond

inferredcites →https://doi.org/10.1039/a709175copenalex-snapshot

The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants†

inferredcites →https://doi.org/10.1039/b002685iopenalex-snapshot

The biosynthesis of C5–C25 terpenoid compounds

inferredcites →https://doi.org/10.1039/b212154aopenalex-snapshot

Antimycobacterial natural products

inferredcites →https://doi.org/10.1039/b311170aopenalex-snapshot

Occurrence, biological activity and synthesis of drimane sesquiterpenoids

inferredcites →https://doi.org/10.1042/bj3240421openalex-snapshot

Expression of an exogenous isopentenyl diphosphate isomerase gene enhances isoprenoid biosynthesis in Escherichia coli

inferredcites →https://doi.org/10.1046/j.1365-2672.2003.02059.xopenalex-snapshot

Antifungal activity of the components of Melaleuca alternifolia (tea tree) oil

inferredcites →https://doi.org/10.1055/s-2006-957666openalex-snapshot

Betulinic Acid: Isolation fromTriphyophyllum peltatumandAncistrocladus heyneanus, Antimalarial Activity, and Crystal Structure of the Benzyl Ester*

inferredcites →https://doi.org/10.1055/s-2006-958045openalex-snapshot

Structural Requirements for the Anti-Inflammatory Activity of Natural Triterpenoids

inferredcites →https://doi.org/10.1073/pnas.0403009101openalex-snapshot

Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis

inferredcites →https://doi.org/10.1073/pnas.0504604102openalex-snapshot

Tuning genetic control through promoter engineering

inferredcites →https://doi.org/10.1073/pnas.0508027103openalex-snapshot

The products of a single maize sesquiterpene synthase form a volatile defense signal that attracts natural enemies of maize herbivores

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Diversity of chemical skeletons

inferred← citeshttps://doi.org/10.1016/b978-0-443-23752-2.00011-6openalex-snapshot

Recent developments in the treatment of leishmaniasis: Natural compounds, drug targets, in silico molecular docking approaches, and nanocarriers

inferred← citeshttps://doi.org/10.1016/b978-0-443-33032-2.00011-3openalex-snapshot

Metabolic engineering for drug production and drug discovery

inferred← citeshttps://doi.org/10.1016/b978-0-444-63505-1.00035-xopenalex-snapshot

Secondary Metabolite Diversity of the Genus Aspergillus: Recent Advances

inferred← citeshttps://doi.org/10.1016/bs.abr.2024.02.011openalex-snapshot

Terpenoids, steroids, and saponins from African medicinal plants as potential pharmaceuticals to fight cancers, and their refractory phenotypes

inferred← citeshttps://doi.org/10.1016/bs.coac.2020.04.006openalex-snapshot

Quantitating terpenes/terpenoids and nicotine in plant materials and vaping products using high-temperature headspace gas chromatography–mass spectrometry

inferred← citeshttps://doi.org/10.1016/bs.mie.2016.02.020openalex-snapshot

Natural Product Biosynthesis in Escherichia coli

inferred← citeshttps://doi.org/10.1016/bs.mie.2016.03.007openalex-snapshot

Engineering Microbes to Synthesize Plant Isoprenoids

inferred← citeshttps://doi.org/10.1016/j.abb.2019.07.025openalex-snapshot

Exploring the substrate specificity of Cytochrome P450cin

inferred← citeshttps://doi.org/10.1016/j.algal.2021.102449openalex-snapshot

Preparative separation of three terpenoids from edible brown algae Sargassum fusiforme by high-speed countercurrent chromatography combined with preparative high-performance liquid chromatography

inferred← citeshttps://doi.org/10.1016/j.bcab.2018.11.027openalex-snapshot

Biosynthesis and biomedical perspectives of carotenoids with special reference to human health-related applications

inferred← citeshttps://doi.org/10.1016/j.bcp.2012.07.015openalex-snapshot

Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancer

inferred← citeshttps://doi.org/10.1016/j.bcp.2014.02.011openalex-snapshot

Novel action modality of the diterpenoid anisomelic acid causes depletion of E6 and E7 viral oncoproteins in HPV-transformed cervical carcinoma cells

inferred← citeshttps://doi.org/10.1016/j.bej.2016.03.010openalex-snapshot

Effect of some abiotic stresses on the biotransformation of α-pinene by a psychrotrophic Chrysosporium pannorum

inferred← citeshttps://doi.org/10.1016/j.bej.2018.11.008openalex-snapshot

De novo biosynthesis of antimycobacterial agent geranylgeranyl acetate from glucose

inferred← citeshttps://doi.org/10.1016/j.bej.2019.01.012openalex-snapshot

Stepwise increase in the production of 13R-manoyl oxide through metabolic engineering of Saccharomyces cerevisiae

inferred← citeshttps://doi.org/10.1016/j.bej.2023.108864openalex-snapshot

Food waste valorization applying the biorefinery concept in the Colombian context: Pre-feasibility analysis of the organic kitchen food waste processing

inferred← citeshttps://doi.org/10.1016/j.biortech.2017.06.058openalex-snapshot

Utilization of biodiesel by-product as substrate for high-production of β-farnesene via relatively balanced mevalonate pathway in Escherichia coli

inferred← citeshttps://doi.org/10.1016/j.biotechadv.2017.03.001openalex-snapshot

Metabolic engineering for the microbial production of marine bioactive compounds

inferred← citeshttps://doi.org/10.1016/j.biotechadv.2018.02.001openalex-snapshot

Recent advances in reconstructing microbial secondary metabolites biosynthesis in Aspergillus spp.

inferred← citeshttps://doi.org/10.1016/j.biotechadv.2021.107837openalex-snapshot

Metabolic engineering of microbes for monoterpenoid production

inferred← citeshttps://doi.org/10.1016/j.bmcl.2016.03.022openalex-snapshot

Design and synthesis of natural product derivatives with selective and improved cytotoxicity based on a sesquiterpene scaffold

inferred← citeshttps://doi.org/10.1016/j.bse.2014.12.013openalex-snapshot

Effects of light and temperature on the odor production of 2-methylisoborneol-producing Pseudanabaena sp. and geosmin-producing Anabaena ucrainica (cyanobacteria)

inferred← citeshttps://doi.org/10.1016/j.cbpa.2012.03.002openalex-snapshot

Bacterial diterpene synthases: new opportunities for mechanistic enzymology and engineered biosynthesis

inferred← citeshttps://doi.org/10.1016/j.ces.2018.09.030openalex-snapshot

Improving lycopene production in Saccharomyces cerevisiae through optimizing pathway and chassis metabolism

inferred← citeshttps://doi.org/10.1016/j.cherd.2018.07.038openalex-snapshot

Liquid–liquid extraction-based process concepts for recovery of carboxylic acids from aqueous streams evaluated for dilute streams

inferred← citeshttps://doi.org/10.1016/j.compag.2018.09.020openalex-snapshot

Manipulating tomato plant electric signaling system by microwave radiation to enhance crop productivity and nutritional value

inferred← citeshttps://doi.org/10.1016/j.copbio.2011.01.002openalex-snapshot

Pathway engineering for functional isoprenoids

inferred← citeshttps://doi.org/10.1016/j.copbio.2015.10.007openalex-snapshot

Developing fermentative terpenoid production for commercial usage

inferred← citeshttps://doi.org/10.1016/j.copbio.2019.09.019openalex-snapshot

Green algal hydrocarbon metabolism is an exceptional source of sustainable chemicals

inferred← citeshttps://doi.org/10.1016/j.crfs.2025.101028openalex-snapshot

Functional compounds in tropical fruit processing by-products and intrinsic factors affecting their composition: A review

inferred← citeshttps://doi.org/10.1016/j.fitote.2024.106323openalex-snapshot

Terpenoids mediated cell apoptotsis in cervical cancer: Mechanisms, advances and prospects

inferred← citeshttps://doi.org/10.1016/j.foodres.2013.01.062openalex-snapshot

Engineered Escherichia coli as new source of flavonoids and terpenoids

inferred← citeshttps://doi.org/10.1016/j.foodres.2021.110871openalex-snapshot

Agro-industrial by-products: Valuable sources of bioactive compounds

inferred← citeshttps://doi.org/10.1016/j.futures.2023.103302openalex-snapshot

Ordering the past, envisioning future(s): How review articles in synthetic biology make use of heterogeneous expectations

inferred← citeshttps://doi.org/10.1016/j.hal.2015.11.008openalex-snapshot

Biochemistry and genetics of taste- and odor-producing cyanobacteria

inferred← citeshttps://doi.org/10.1016/j.ica.2015.10.045openalex-snapshot

Oxidoperoxidotungsten(VI) and dioxidotungsten(VI) complexes catalyzed oxidative bromination of thymol in presence of H2O2–KBr–HClO4

inferred← citeshttps://doi.org/10.1016/j.indcrop.2013.02.012openalex-snapshot

Assessment of the terpenic profile of Callistemon citrinus (Curtis) Skeels from Mexico

inferred← citeshttps://doi.org/10.1016/j.indcrop.2014.09.023openalex-snapshot

Comprehensive two-dimensional gas chromatography with mass spectrometry applied to the analysis of volatiles in artichoke (Cynara scolymus L.) leaves

inferred← citeshttps://doi.org/10.1016/j.jbiosc.2013.12.018openalex-snapshot

Prerequisite for highly efficient isoprenoid production by cyanobacteria discovered through the over-expression of 1-deoxy-d-xylulose 5-phosphate synthase and carbon allocation analysis

inferred← citeshttps://doi.org/10.1016/j.jbiosc.2016.10.005openalex-snapshot

Exploration of the 1-deoxy-d-xylulose 5-phosphate synthases suitable for the creation of a robust isoprenoid biosynthesis system

inferred← citeshttps://doi.org/10.1016/j.jbiotec.2015.09.016openalex-snapshot

Metabolic engineering of the Stevia rebaudiana ent-kaurene biosynthetic pathway in recombinant Escherichia coli

inferred← citeshttps://doi.org/10.1016/j.jbiotec.2015.09.042openalex-snapshot

Engineering of genetic control tools in Synechocystis sp. PCC 6803 using rational design techniques

inferred← citeshttps://doi.org/10.1016/j.jff.2017.10.022openalex-snapshot

Lactic acid fermentation enriches the profile of biogenic compounds and enhances the functional features of common purslane ( Portulaca oleracea L.)

inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2021.111636openalex-snapshot

Making and breaking carbon-carbon bonds in class C radical SAM methyltransferases

inferred← citeshttps://doi.org/10.1016/j.marpolbul.2022.113579openalex-snapshot

Undesirable odour substances (geosmin and 2-methylisoborneol) in water environment: Sources, impacts and removal strategies

inferred← citeshttps://doi.org/10.1016/j.mec.2021.e00164openalex-snapshot

Enhanced limonene production in a fast-growing cyanobacterium through combinatorial metabolic engineering

inferred← citeshttps://doi.org/10.1016/j.mec.2021.e00173openalex-snapshot

Engineering Acinetobacter baylyi ADP1 for mevalonate production from lignin-derived aromatic compounds

inferred← citeshttps://doi.org/10.1016/j.mec.2022.e00193openalex-snapshot

Thermodynamics contributes to high limonene productivity in cyanobacteria

inferred← citeshttps://doi.org/10.1016/j.molcatb.2016.03.004openalex-snapshot

In vivo and in vitro hydroxylation of cineole and camphor by cytochromes P450CYP101A1, CYP101B1 and N242A CYP176A1

inferred← citeshttps://doi.org/10.1016/j.molliq.2021.115951openalex-snapshot

Recent advances in essential oils-based metal nanoparticles: A review on recent developments and biopharmaceutical applications

inferred← citeshttps://doi.org/10.1016/j.phanu.2020.100240openalex-snapshot

Anti-inflammatory effects of monoterpenoids in rats with TNBS-induced colitis

inferred← citeshttps://doi.org/10.1016/j.phytochem.2017.02.017openalex-snapshot

Converting S-limonene synthase to pinene or phellandrene synthases reveals the plasticity of the active site

inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112541openalex-snapshot

Headspace GC-MS analysis of differences in intra- and interspecific Terpene profiles of Picea pungens Engelm. and P. abies (L.) Karst

inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112573openalex-snapshot

Probing of the plasticity of the active site in pinene synthase elucidates its potential evolutionary mechanism

inferred← citeshttps://doi.org/10.1016/j.plantsci.2021.110960openalex-snapshot

Reassessing the evolution of the 1-deoxy-D-xylulose 5-phosphate synthase family suggests a possible novel function for the DXS class 3 proteins

inferred← citeshttps://doi.org/10.1016/j.plipres.2016.04.002openalex-snapshot

Isoprenoid generating systems in plants — A handy toolbox how to assess contribution of the mevalonate and methylerythritol phosphate pathways to the biosynthetic process

inferred← citeshttps://doi.org/10.1016/j.poly.2015.05.001openalex-snapshot

Oxidative bromination of monoterpene (thymol) using dioxidomolybdenum(VI) complexes of hydrazones of 8-formyl-7-hydroxy-4-methylcoumarin

inferred← citeshttps://doi.org/10.1016/j.polymdegradstab.2019.01.025openalex-snapshot

Valencene as a naturally occurring sesquiterpene monomer for radical copolymerization with maleimide to induce concurrent 1:1 and 1:2 propagation

inferred← citeshttps://doi.org/10.1016/j.procbio.2011.06.010openalex-snapshot

Biooxidation of monoterpenes with bacterial monooxygenases

inferred← citeshttps://doi.org/10.1016/j.procbio.2012.02.027openalex-snapshot

Biodegradation of di-n-butyl phthalate and expression of the 3,4-phthalate dioxygenase gene in Arthrobacter sp. ZH2 strain

inferred← citeshttps://doi.org/10.1016/j.procbio.2014.12.008openalex-snapshot

Targeted engineering and scale up of lycopene overproduction in Escherichia coli

inferred← citeshttps://doi.org/10.1016/j.procbio.2024.01.027openalex-snapshot

Cell factories for methylerythritol phosphate pathway mediated terpenoid biosynthesis: An application of modern engineering towards sustainability

inferred← citeshttps://doi.org/10.1016/j.psep.2023.02.088openalex-snapshot

Flash point of binary and ternary monoterpene mixtures: Experimental and modeling

inferred← citeshttps://doi.org/10.1016/j.resmic.2022.103938openalex-snapshot

Isoprene production by Rhodobacter sphaeroides and its antimicrobial activity

inferred← citeshttps://doi.org/10.1016/j.seppur.2025.131837openalex-snapshot

Sustainable in situ extraction of microalgae-derived terpenoids using functionalized silica microparticles

inferred← citeshttps://doi.org/10.1016/j.supflu.2010.04.010openalex-snapshot

Pd-catalyzed allylic amination in supercritical carbon dioxide: Synthesis of carborane-containing terpenoids

inferred← citeshttps://doi.org/10.1016/j.supflu.2022.105558openalex-snapshot

Hydroalcoholic extraction of bioactive compounds from expeller soybean meal under subcritical conditions

inferred← citeshttps://doi.org/10.1016/j.tetlet.2021.153162openalex-snapshot

Labeling of prenylated nucleic acid by Ene-type fluorination under physiological condition

inferred← citeshttps://doi.org/10.1016/j.tibtech.2008.08.003openalex-snapshot

Engineering microbes with synthetic biology frameworks

inferred← citeshttps://doi.org/10.1016/j.tibtech.2015.04.006openalex-snapshot

Plant diterpene synthases: exploring modularity and metabolic diversity for bioengineering

inferred← citeshttps://doi.org/10.1016/j.tibtech.2024.08.010openalex-snapshot

Semi-continuous biomanufacturing for maximizing the production of complex chemicals and fuels: a case study of amorpha-4,11-diene

inferred← citeshttps://doi.org/10.1016/j.ymben.2011.05.001openalex-snapshot

Harnessing yeast subcellular compartments for the production of plant terpenoids

inferred← citeshttps://doi.org/10.1016/j.ymben.2012.01.007openalex-snapshot

Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene α-santalene in a fed-batch mode

inferred← citeshttps://doi.org/10.1016/j.ymben.2012.02.001openalex-snapshot

The future of metabolic engineering and synthetic biology: Towards a systematic practice

inferred← citeshttps://doi.org/10.1016/j.ymben.2013.02.002openalex-snapshot

Engineering central metabolic modules of Escherichia coli for improving β-carotene production

inferred← citeshttps://doi.org/10.1016/j.ymben.2013.10.004openalex-snapshot

Metabolic engineering of Saccharomyces cerevisiae for production of ginsenosides

inferred← citeshttps://doi.org/10.1016/j.ymben.2014.10.008openalex-snapshot

Efficient diterpene production in yeast by engineering Erg20p into a geranylgeranyl diphosphate synthase

inferred← citeshttps://doi.org/10.1016/j.ymben.2014.11.007openalex-snapshot

Sequential control of biosynthetic pathways for balanced utilization of metabolic intermediates in Saccharomyces cerevisiae

inferred← citeshttps://doi.org/10.1016/j.ymben.2015.04.009openalex-snapshot

Construction of lycopene-overproducing Saccharomyces cerevisiae by combining directed evolution and metabolic engineering

inferred← citeshttps://doi.org/10.1016/j.ymben.2015.09.004openalex-snapshot

Engineering Methylobacterium extorquens for de novo synthesis of the sesquiterpenoid α-humulene from methanol

inferred← citeshttps://doi.org/10.1016/j.ymben.2016.05.003openalex-snapshot

Synergy between methylerythritol phosphate pathway and mevalonate pathway for isoprene production in Escherichia coli

inferred← citeshttps://doi.org/10.1016/j.ymben.2016.10.003openalex-snapshot

Precise precursor rebalancing for isoprenoids production by fine control of gapA expression in Escherichia coli

inferred← citeshttps://doi.org/10.1016/j.ymben.2017.07.001openalex-snapshot

Membrane engineering - A novel strategy to enhance the production and accumulation of β-carotene in Escherichia coli

inferred← citeshttps://doi.org/10.1016/j.ymben.2017.08.005openalex-snapshot

Balanced activation of IspG and IspH to eliminate MEP intermediate accumulation and improve isoprenoids production in Escherichia coli

inferred← citeshttps://doi.org/10.1016/j.ymben.2017.12.010openalex-snapshot

Tailored carbon partitioning for phototrophic production of (E)-α-bisabolene from the green microalga Chlamydomonas reinhardtii

inferred← citeshttps://doi.org/10.1016/j.ymben.2019.07.007openalex-snapshot

Systematic engineering for high-yield production of viridiflorol and amorphadiene in auxotrophic Escherichia coli

inferred← citeshttps://doi.org/10.1016/j.ymben.2019.12.004openalex-snapshot

Metabolic flux ratio analysis by parallel 13C labeling of isoprenoid biosynthesis in Rhodobacter sphaeroides

inferred← citeshttps://doi.org/10.1016/j.ymben.2020.08.010openalex-snapshot

Engineering Saccharomyces cerevisiae for high yield production of α-amyrin via synergistic remodeling of α-amyrin synthase and expanding the storage pool

inferred← citeshttps://doi.org/10.1016/j.ymben.2021.10.007openalex-snapshot

Lepidopteran mevalonate pathway optimization in Escherichia coli efficiently produces isoprenol analogs for next-generation biofuels

inferred← citeshttps://doi.org/10.1016/j.ymben.2023.03.002openalex-snapshot

Plastidial engineering with coupled farnesyl diphosphate pool reconstitution and enhancement for sesquiterpene biosynthesis in tomato fruit

inferred← citeshttps://doi.org/10.1016/j.ymben.2024.04.003openalex-snapshot

Efficient production of (S)-limonene and geraniol in Saccharomyces cerevisiae through the utilization of an Erg20 mutant with enhanced GPP accumulation capability

inferred← citeshttps://doi.org/10.1016/j.yrtph.2017.05.003openalex-snapshot

Safety assessment of astaxanthin derived from engineered Escherichia coli K-12 using a 13-week repeated dose oral toxicity study and a prenatal developmental toxicity study in rats

inferred← citeshttps://doi.org/10.1021/acs.biochem.1c00600openalex-snapshot

Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase

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