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Exploiting the Nanoparticle Plasmon Effect: Observing Drug Delivery Dynamics in Single Cells via Raman/Fluorescence Imaging Spectroscopy

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Remotely Triggerable Drug Delivery Systems
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A Temperature‐Sensitive Drug Release System Based on Phase‐Change Materials
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Feasibility of quantitative determination of doxorubicin with surface‐enhanced Raman spectroscopy
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Role of the αvβ6 Integrin in Human Oral Squamous Cell Carcinoma Growth in Vivo and in Vitro
inferredcites →https://doi.org/10.1016/0092-8674(91)90245-topenalex-snapshot
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: Identification of a class of bipartite nuclear targeting sequence
inferredcites →https://doi.org/10.1016/0968-0004(91)90184-wopenalex-snapshot
Nuclear targeting sequences — a consensus?
inferredcites →https://doi.org/10.1016/j.addr.2010.09.002openalex-snapshot
Development and applications of photo-triggered theranostic agents
inferredcites →https://doi.org/10.1016/s1386-1425(01)00453-xopenalex-snapshot
Multivariate evaluation of doxorubicin surface-enhanced Raman spectra
inferredcites →https://doi.org/10.1021/bc070132iopenalex-snapshot
Peptide-Conjugated Gold Nanorods for Nuclear Targeting
inferredcites →https://doi.org/10.1021/bc200386mopenalex-snapshot
Nuclear Targeted Silver Nanospheres Perturb the Cancer Cell Cycle Differently than Those of Nanogold
inferredcites →https://doi.org/10.1021/ja057254aopenalex-snapshot
Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods
inferredcites →https://doi.org/10.1021/ja064328popenalex-snapshot
Gold Nanoparticles Propulsion from Surface Fueled by Absorption of Femtosecond Laser Pulse at Their Surface Plasmon Resonance
inferredcites →https://doi.org/10.1021/ja1022267openalex-snapshot
Noninvasive Remote-Controlled Release of Drug Molecules in Vitro Using Magnetic Actuation of Mechanized Nanoparticles
inferredcites →https://doi.org/10.1021/ja207807topenalex-snapshot
Plasmonic Imaging of Human Oral Cancer Cell Communities during Programmed Cell Death by Nuclear-Targeting Silver Nanoparticles
inferredcites →https://doi.org/10.1021/ja4011145openalex-snapshot
A New Nanotechnology Technique for Determining Drug Efficacy Using Targeted Plasmonically Enhanced Single Cell Imaging Spectroscopy
inferredcites →https://doi.org/10.1021/ja900025fopenalex-snapshot
Photoinduced Intracellular Controlled Release Drug Delivery in Human Cells by Gold-Capped Mesoporous Silica Nanosphere
inferredcites →https://doi.org/10.1021/ja9102698openalex-snapshot
Nuclear Targeting of Gold Nanoparticles in Cancer Cells Induces DNA Damage, Causing Cytokinesis Arrest and Apoptosis
inferredcites →https://doi.org/10.1021/jp061667wopenalex-snapshot
Turkevich Method for Gold Nanoparticle Synthesis Revisited
inferredcites →https://doi.org/10.1021/nl052441sopenalex-snapshot
Distance-Dependent Fluorescence Quenching on Gold Nanoparticles Ensheathed with Layer-by-Layer Assembled Polyelectrolytes
inferredcites →https://doi.org/10.1021/nl3027586openalex-snapshot
Real-Time Molecular Imaging throughout the Entire Cell Cycle by Targeted Plasmonic-Enhanced Rayleigh/Raman Spectroscopy
inferredcites →https://doi.org/10.1038/nature08907openalex-snapshot
Shell-isolated nanoparticle-enhanced Raman spectroscopy
inferredcites →https://doi.org/10.1038/nmat2564openalex-snapshot
Gold nanocages covered by smart polymers for controlled release with near-infrared light
inferredcites →https://doi.org/10.1039/b910431copenalex-snapshot
pH-Responsive mechanised nanoparticles gated by semirotaxanes
inferredcites →https://doi.org/10.1039/b914071aopenalex-snapshot
Doxorubicin conjugated gold nanoparticles as water-soluble and pH-responsive anticancer drug nanocarriers
inferredcites →https://doi.org/10.1039/c0cs00180eopenalex-snapshot
Beating cancer in multiple ways using nanogold
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The golden age: gold nanoparticles for biomedicine
inferredcites →https://doi.org/10.1073/pnas.0502746102openalex-snapshot
Single-cell Raman and fluorescence microscopy reveal the association of lipid bodies with phagosomes in leukocytes
inferredcites →https://doi.org/10.1073/pnas.1009043108openalex-snapshot
In vivo lipidomics using single-cell Raman spectroscopy
inferredcites →https://doi.org/10.1103/physrevlett.89.203002openalex-snapshot
Fluorescence Quenching of Dye Molecules near Gold Nanoparticles: Radiative and Nonradiative Effects
inferredcites →https://doi.org/10.1117/1.3477179openalex-snapshot
Dark-field light scattering imaging of living cancer cell component from birth through division using bioconjugated gold nanoprobes
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The early endosome: a busy sorting station for proteins at the crossroads.
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Inhibition of TGF-β1 suppresses motility and invasiveness of oral squamous cell carcinoma cell lines via modulation of integrins and down-regulation of matrix-metalloproteinases
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The Study of Doxorubicin and its Complex with DNA by SERS and UV-resonance Raman Spectroscopy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Concluding remarks: Summary of some of our recent studies in the field of conjugating plasmonic gold nanoparticles to single cancer cells and their molecular and cellular dynamics
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Controllable photophysical properties and self-assembly of siloxane-poly(amidoamine) dendrimers
inferred← citeshttps://doi.org/10.1039/c5nr05619eopenalex-snapshot
Study of the nucleation and growth of antibiotic labeled Au NPs and blue luminescent Au 8 quantum clusters for Hg 2+ ion sensing, cellular imaging and antibacterial applications
inferred← citeshttps://doi.org/10.1039/c5ra25575aopenalex-snapshot
Localized surface plasmon resonance on Au nanoparticles: tuning and exploitation for performance enhancement in ultrathin photovoltaics
inferred← citeshttps://doi.org/10.1039/c5tb00994dopenalex-snapshot
Synthesis of silver nanoparticles for the dual delivery of doxorubicin and alendronate to cancer cells
inferred← citeshttps://doi.org/10.1039/c5tb02045jopenalex-snapshot
Photoresponsive real time monitoring silicon quantum dots for regulated delivery of anticancer drugs
inferred← citeshttps://doi.org/10.1039/c6an01003bopenalex-snapshot
Nanoparticles and intracellular applications of surface-enhanced Raman spectroscopy
inferred← citeshttps://doi.org/10.1039/c6nr00987eopenalex-snapshot
Intelligent Janus nanoparticles for intracellular real-time monitoring of dual drug release
inferred← citeshttps://doi.org/10.1039/c6nr07660bopenalex-snapshot
Enhanced luminescence of Au 22 (SG) 18 nanoclusters via rational surface engineering
inferred← citeshttps://doi.org/10.1039/c6ra19062fopenalex-snapshot
Facile one-pot synthesis of novel water-soluble fluorescent hyperbranched poly(amino esters)
inferred← citeshttps://doi.org/10.1039/c6ra22706fopenalex-snapshot
Gold nanoflowers modified ITO glass as SERS substrate for carbon tetrachloride-induced acute liver injury in vitro detection
inferred← citeshttps://doi.org/10.1039/c6ra28450gopenalex-snapshot
Optimizing the SERS enhancement of a facile gold nanostar immobilized paper-based SERS substrate
inferred← citeshttps://doi.org/10.1039/c6sc02486fopenalex-snapshot
Plasmon-enhanced Raman spectroscopic metrics for in situ quantitative and dynamic assays of cell apoptosis and necrosis
inferred← citeshttps://doi.org/10.1039/c7fd00156hopenalex-snapshot
What do we actually see in intracellular SERS? Investigating nanosensor-induced variation
inferred← citeshttps://doi.org/10.1039/c7nr09218kopenalex-snapshot
Thermoresponsive plasmonic core–satellite nanostructures with reversible, temperature sensitive optical properties
inferred← citeshttps://doi.org/10.1039/c7py00161dopenalex-snapshot
“Click” functionalization of dual stimuli-responsive polymer nanocapsules for drug delivery systems
inferred← citeshttps://doi.org/10.1039/c7tb03063kopenalex-snapshot
Switching off the interactions between graphene oxide and doxorubicin using vitamin C: combining simplicity and efficiency in drug delivery
inferred← citeshttps://doi.org/10.1039/c7tc03069jopenalex-snapshot
One-step synthesis of a monolayer of monodisperse gold nanocubes for SERS substrates
inferred← citeshttps://doi.org/10.1039/c8an01079jopenalex-snapshot
Single-cell assay on microfluidic devices
inferred← citeshttps://doi.org/10.1039/c8an01461bopenalex-snapshot
Tandem fluorescence and Raman (fluoRaman) characterisation of a novel photosensitiser in colorectal cancer cell line SW480
inferred← citeshttps://doi.org/10.1039/c8nj02561dopenalex-snapshot
SERS based protocol using flow glass-hemostix for detection of neuron-specific enolase in blood plasma
inferred← citeshttps://doi.org/10.1039/c8nr02099jopenalex-snapshot
Radiation of the high-order plasmonic modes of large gold nanospheres excited by surface plasmon polaritons
inferred← citeshttps://doi.org/10.1039/c8sc05035jopenalex-snapshot
Label-free plasmonic nanostar probes to illuminate in vitro membrane receptor recognition
inferred← citeshttps://doi.org/10.1039/c9nr00041kopenalex-snapshot
Design of Raman tag-bridged core–shell Au@Cu 3 (BTC) 2 nanoparticles for Raman imaging and synergistic chemo-photothermal therapy
inferred← citeshttps://doi.org/10.1039/d0tc01280gopenalex-snapshot
Shape control of silver nanoparticles and their stability on Al 2 O 3
inferred← citeshttps://doi.org/10.1039/d5ja00253bopenalex-snapshot
A novel particle mass calibration strategy for the quantification of AuNPs in single cancer cells via laser ablation ICP-mass spectrometry. A case study
inferred← citeshttps://doi.org/10.1039/d5sc03803kopenalex-snapshot
Monitoring structural change and drug release of responsive nanoparticles using polarity-sensitive fluorophores
inferred← citeshttps://doi.org/10.1063/10.0024970openalex-snapshot
Clusteroluminogenic polymers: Applications in biology and medicine (Review article)
inferred← citeshttps://doi.org/10.1080/03602532.2017.1302465openalex-snapshot
Raman spectroscopy using plasmonic and carbon-based nanoparticles for cancer detection, diagnosis, and treatment guidance.Part 1: Diagnosis
inferred← citeshttps://doi.org/10.1080/03602532.2017.1307387openalex-snapshot
Raman spectroscopy using plasmonic and carbon-based nanoparticles for cancer detection, diagnosis, and treatment guidance. Part 2: Treatment
inferred← citeshttps://doi.org/10.1080/10408347.2025.2453431openalex-snapshot
Analysis of Drug Molecules in Living Cells
inferred← citeshttps://doi.org/10.1103/physrevapplied.19.024049openalex-snapshot
Nanomotion of Micro-Objects Driven by Light-Induced Elastic Waves on Solid Interfaces
inferred← citeshttps://doi.org/10.1111/odi.13551openalex-snapshot
Function of gold nanoparticles in oral cancer beyond drug delivery: Implications in cell apoptosis
inferred← citeshttps://doi.org/10.1117/12.2085720openalex-snapshot
Dynamics of plasmon in graphene oxide
inferred← citeshttps://doi.org/10.1166/jbn.2022.3246openalex-snapshot
Recent Advances in Engineered Noble Metal Nanomaterials as a Surface-Enhanced Raman Scattering Active Platform for Cancer Diagnostics
inferred← citeshttps://doi.org/10.1186/s11671-019-3232-3openalex-snapshot
One-step, Rapid and Green Synthesis of Multifunctional Gold Nanoparticles for Tumor-Targeted Imaging and Therapy
inferred← citeshttps://doi.org/10.1186/s12885-021-07849-xopenalex-snapshot
Following cytotoxic nanoconjugates from injection to halting the cell cycle machinery and its therapeutic implications in oral cancer
inferred← citeshttps://doi.org/10.1186/s12951-015-0129-xopenalex-snapshot
Synthesis of novel galactose functionalized gold nanoparticles and its radiosensitizing mechanism
inferred← citeshttps://doi.org/10.12794/metadc984137openalex-snapshot
Disease Tissue Imaging and Single Cell Analysis with Mass Spectrometry
inferred← citeshttps://doi.org/10.1515/nanoph-2018-0219openalex-snapshot
Recent advances in drug release monitoring
inferred← citeshttps://doi.org/10.1515/nanoph-2023-0362openalex-snapshot
Recent advances in SERS‐based bioanalytical applications: live cell imaging
inferred← citeshttps://doi.org/10.1515/revce-2018-0051openalex-snapshot
Green gold nanoparticles from plant-derived materials: an overview of the reaction synthesis types, conditions, and applications
inferred← citeshttps://doi.org/10.1533/9781908818782.249openalex-snapshot
Gold nanoparticles and their applications in photomedicine, diagnosis and therapy
inferred← citeshttps://doi.org/10.1557/s43579-025-00784-zopenalex-snapshot
Surface engineering of theranostic nanomaterials for intracellular trafficking and localization
inferred← citeshttps://doi.org/10.18054/pb.v125i1-2.23726openalex-snapshot
Interactions of variously coated gold and silver nanoparticles with a bis(triarylborane) photodyanmic therapy (PDT)-dye; their cellular uptake, cytotoxicity and photo-activity
inferred← citeshttps://doi.org/10.21037/atm-21-3462openalex-snapshot
In vivo reflectance confocal microscopy of wounds: feasibility of intraoperative basal cell carcinoma margin assessment
inferred← citeshttps://doi.org/10.2147/ijn.s97476openalex-snapshot
Targeted polyethylene glycol gold nanoparticles for the treatment of pancreatic cancer: from synthesis to proof-of-concept in vitro studies
inferred← citeshttps://doi.org/10.3109/03602532.2013.873451openalex-snapshot
Applications of surface-enhanced Raman scattering in advanced bio-medical technologies and diagnostics
inferred← citeshttps://doi.org/10.3389/fphar.2019.01369openalex-snapshot
Recalcitrant Issues and New Frontiers in Nano-Pharmacology
inferred← citeshttps://doi.org/10.3390/app8071106openalex-snapshot
Bimetallic Nanoparticles: Enhanced Magnetic and Optical Properties for Emerging Biological Applications
inferred← citeshttps://doi.org/10.3390/cancers13215317openalex-snapshot
Delivery Capacity and Anticancer Ability of the Berberine-Loaded Gold Nanoparticles to Promote the Apoptosis Effect in Breast Cancer
inferred← citeshttps://doi.org/10.3390/ijms23020839openalex-snapshot
Cancer Therapy by Silver Nanoparticles: Fiction or Reality?
inferred← citeshttps://doi.org/10.3390/molecules25030561openalex-snapshot
Molecular Spectroscopic Markers of DNA Damage
inferred← citeshttps://doi.org/10.3390/molecules26216476openalex-snapshot
Revealing DNA Structure at Liquid/Solid Interfaces by AFM-Based High-Resolution Imaging and Molecular Spectroscopy
inferred← citeshttps://doi.org/10.3390/nano7040083openalex-snapshot
Investigating the Origins of Toxic Response in TiO2 Nanoparticle-Treated Cells
inferred← citeshttps://doi.org/10.3390/nano8110880openalex-snapshot
A Novel Fast Photothermal Therapy Using Hot Spots of Gold Nanorods for Malignant Melanoma Cells
inferred← citeshttps://doi.org/10.3390/pharmaceutics15051385openalex-snapshot
Therapeutic Applications of Mesenchymal Stem Cell Loaded with Gold Nanoparticles for Regenerative Medicine
inferred← citeshttps://doi.org/10.3390/s150715684openalex-snapshot
Localized Surface Plasmon Resonance Biosensing: Current Challenges and Approaches
inferred← citeshttps://doi.org/10.3390/s17071592openalex-snapshot
Raman Plus X: Biomedical Applications of Multimodal Raman Spectroscopy
inferred← citeshttps://doi.org/10.70675/009b54b8zbc2bz4c26z8fd3zfc3007dda1faopenalex-snapshot
Développement de nanovecteurs à base de nanoparticules d'or : Applications biomédicales
inferred← citeshttps://doi.org/10.70675/6b6be052z21dcz48f0z9c9cza41318c93cb3openalex-snapshot
Nanoparticules en environnement cellulaire : Impact de la nano-architecture sur l'internalisation, la biodégradation et les fonctionnalités thérapeutiques.
inferred← citeshttps://doi.org/10.70675/c0228df9z6f95z4d79z9e48z4380af62789aopenalex-snapshot
New way of synthesis of uniform gold nanoparticles for the detection of few molecules
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