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Comparison of Gold Nanoparticle Mediated Photoporation: Vapor Nanobubbles Outperform Direct Heating for Delivering Macromolecules in Live Cells

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Plasmonic Nanobubbles Enhance Efficacy and Selectivity of Chemotherapy Against Drug‐Resistant Cancer Cells
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Gene Transfer Methods for CNS Organotypic Cultures: A Comparison of Three Nonviral Methods
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High efficiency transformation by direct microinjection of DNA into cultured mammalian cells
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Physical methods for gene transfer: Improving the kinetics of gene delivery into cells
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Physical energy for drug delivery; poration, concentration and activation
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Understanding ultrasound induced sonoporation: Definitions and underlying mechanisms
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Off-resonance plasmonic enhanced femtosecond laser optoporation and transfection of cancer cells
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Cell-specific transmembrane injection of molecular cargo with gold nanoparticle-generated transient plasmonic nanobubbles
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Prolonged gene silencing by combining siRNA nanogels and photochemical internalization
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Endosomal escape pathways for delivery of biologicals
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Enhanced drug delivery via hyperthermal membrane disruption using targeted gold nanoparticles with PEGylated Protein-G as a cofactor
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Laser-Induced Size Reduction of Noble Metal Particles
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The Role of Metal Nanoparticles in Remote Release of Encapsulated Materials
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Influence of Transient Environmental Photothermal Effects on Optical Scattering by Gold Nanoparticles
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Nanoplasmonics for Dual-Molecule Release through Nanopores in the Membrane of Red Blood Cells
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Targeted transfection by femtosecond laser
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Delivery of molecules into cells using carbon nanoparticles activated by femtosecond laser pulses
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Membrane disruption by optically controlled microbubble cavitation
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Current prospects for RNA interference-based therapies
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Prediction and optimization of gene transfection and drug delivery by electroporation
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Bio-chip for spatially controlled transfection of nucleic acid payloads into cells in a culture
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Drug loaded microbubble design for ultrasound triggered delivery
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Thermophysical and biological responses of gold nanoparticle laser heating
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Pulsed laser triggered high speed microfluidic fluorescence activated cell sorter
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Size reduction of gold particles in aqueous solution by pulsed laser irradiation
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Genetic transformation of mouse embryos by microinjection of purified DNA.
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High-efficiency gene transfer into skeletal muscle mediated by electric pulses
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Highly efficient electro-gene therapy of solid tumor by using an expression plasmid for the herpes simplex virus thymidine kinase gene
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Single cell optical transfection
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Photothermal imaging of nanoparticles and cells
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Irreversible Electroporation in Medicine
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Electrical Impedance Monitoring of Photothermal Porated Mammalian Cells
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Optical excitation and detection of vapor bubbles around plasmonic nanoparticles
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The development and application of femtosecond laser systems
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Production of functional transgenic mice by DNA pronuclear microinjection.
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Efficient electroporation of liposomes doped with pore stabilizing nisin

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Polydopamine Nanoparticle‐Sensitized Photoporation Delivers Macromolecules in Monocytes and Macrophages with Minimal Impact on Cell Homeostasis
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Laser-Induced Bubble Generation on Excitation of Gold Nanoparticles
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Interactions of Biomaterial Surfaces with Proteins and Cells
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Plasma membrane perforation by GSDME during apoptosis-driven secondary necrosis
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Transient nuclear lamin A/C accretion aids in recovery from vapor nanobubble-induced permeabilisation of the plasma membrane
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The feasibility of using irreversible electroporation to introduce pores in bacterial cellulose scaffolds for tissue engineering
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Photothermal Heating of Au Nanorods and Nanospheres: Temperature Characteristics and Strength of Convective Forces
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Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation
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Intracellular Delivery of mRNA in Adherent and Suspension Cells by Vapor Nanobubble Photoporation
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Near-Infrared Photothermal Heating With Gold Nanostructures
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Photoporation enables non-viral delivery of prime editing RNP complexes into human iPSC-derived cardiomyocytes for cardiac genome correction
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Non-viral transfection technologies for next-generation therapeutic T cell engineering
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Pharmacological aspects of release from microcapsules — from polymeric multilayers to lipid membranes
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Comparing photoporation and nucleofection for delivery of small interfering RNA to cytotoxic T cells
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Fast spatial-selective delivery into live cells
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Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis
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ICG-mediated photodisruption of the inner limiting membrane enhances retinal drug delivery
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Nanomaterials to avoid and destroy protein aggregates
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Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering
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Continuous-wave laser-assisted injection of single magnetic nanobeads into living cells
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Comparative Analysis Based on Near-Field Electromagnetic Theory Combined with Molecular Dynamics for Pulse Light-Induced Plasmonic Nanobubble in Gold and Silver Nanofluids
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Au Nanoparticles in Lipid Bilayers: A Comparison between Atomistic and Coarse-Grained Models
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Quantitative Evaluation and Optimization of Photothermal Bubble Generation around Overheated Nanoparticles Excited by Pulsed Lasers
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Single-Step Nanoporation of Water-Immersed Polystyrene Film by Gaseous Nanobubbles
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Multiresonant Composite Optical Nanoantennas by Out-of-plane Plasmonic Engineering
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Photothermal Micro-Nano Solid Substrates for Intracellular Delivery via Laser-Assisted Photoporation
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Sub-10 nm Nanolaminated Al2O3/HfO2 Coatings for Long-Term Stability of Cu Plasmonic Nanodisks in Physiological Environments
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Surface-Mediated Intracellular Delivery by Physical Membrane Disruption
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A Photothermal Nanoplatform with Sugar-Triggered Cleaning Ability for High-Efficiency Intracellular Delivery
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A Photothermal Polymeric Platform for Efficient and Safe Gene Transfection: When Polyethylenimine Collaborates with Indocyanine Green
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Photothermal Intracellular Delivery Using Gold Nanodisk Arrays
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Real-Time Optical Measurements of Nanoparticle-Induced Melting and Resolidification Dynamics
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Nonequilibrium Dynamic Phase Diagram for Transmembrane Transport of Active Particles
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Intracellular Delivery Using Nanosecond-Laser Excitation of Large-Area Plasmonic Substrates
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Local Enhancement of Lipid Membrane Permeability Induced by Irradiated Gold Nanoparticles
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Targeted Perturbation of Nuclear Envelope Integrity with Vapor Nanobubble-Mediated Photoporation
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Transient Photoinactivation of Cell Membrane Protein Activity without Genetic Modification by Molecular Hyperthermia
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Intracellular Photothermal Delivery for Suspension Cells Using Sharp Nanoscale Tips in Microwells
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Gold-Nanoshell-Functionalized Polymer Nanoswimmer for Photomechanical Poration of Single-Cell Membrane
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Optical Injection of Gold Nanoparticles into Living Cells
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Optical delivery of multiple opsin-encoding genes leads to targeted expression and white-light activation
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In vitro and ex vivo strategies for intracellular delivery
inferred← citeshttps://doi.org/10.1038/s41377-018-0048-3openalex-snapshot
Repeated photoporation with graphene quantum dots enables homogeneous labeling of live cells with extrinsic markers for fluorescence microscopy
inferred← citeshttps://doi.org/10.1038/s41467-018-06884-wopenalex-snapshot
Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms
inferred← citeshttps://doi.org/10.1038/s41565-021-00976-3openalex-snapshot
Photothermal nanofibres enable safe engineering of therapeutic cells
inferred← citeshttps://doi.org/10.1038/s41565-022-01086-4openalex-snapshot
Laser-induced nanobubbles safely ablate vitreous opacities in vivo
inferred← citeshttps://doi.org/10.1038/s41596-021-00631-0openalex-snapshot
Fabrication and use of silicon hollow-needle arrays to achieve tissue nanotransfection in mouse tissue in vivo
inferred← citeshttps://doi.org/10.1038/s41596-024-01115-7openalex-snapshot
Photothermal nanofiber-mediated photoporation for gentle and efficient intracellular delivery of macromolecules
inferred← citeshttps://doi.org/10.1038/s41598-020-80953-3openalex-snapshot
Non-disruptive uptake of anionic and cationic gold nanoparticles in neutral zwitterionic membranes
inferred← citeshttps://doi.org/10.1039/c5nr05650kopenalex-snapshot
Cell-specific optoporation with near-infrared ultrafast laser and functionalized gold nanoparticles
inferred← citeshttps://doi.org/10.1039/c8nr09617aopenalex-snapshot
pH-Dependent aggregation and pH-independent cell membrane adhesion of monolayer-protected mixed charged gold nanoparticles
inferred← citeshttps://doi.org/10.1039/c8qm00449hopenalex-snapshot
Gold nanoparticle layer: a versatile nanostructured platform for biomedical applications
inferred← citeshttps://doi.org/10.1039/c8tb01026aopenalex-snapshot
Using porous magnetic iron oxide nanomaterials as a facile photoporation nanoplatform for macromolecular delivery
inferred← citeshttps://doi.org/10.1039/c8tb02484gopenalex-snapshot
Current status and future perspectives of gold nanoparticle vectors for siRNA delivery
inferred← citeshttps://doi.org/10.1039/c9cp01293aopenalex-snapshot
Amphiphilic copolymers change the nature of the ordered-to-disordered phase transition of lipid membranes from discontinuous to continuous
inferred← citeshttps://doi.org/10.1039/c9cs00839jopenalex-snapshot
Stimuli-responsive nanobubbles for biomedical applications
inferred← citeshttps://doi.org/10.1039/c9sm01856eopenalex-snapshot
Microchamber arrays made of biodegradable polymers for enzymatic release of small hydrophilic cargos
inferred← citeshttps://doi.org/10.1039/d0bm01485kopenalex-snapshot
Biomaterials-based approaches to model embryogenesis
inferred← citeshttps://doi.org/10.1039/d0na00094aopenalex-snapshot
Water dynamics affects thermal transport at the surface of hydrophobic and hydrophilic irradiated nanoparticles
inferred← citeshttps://doi.org/10.1039/d0nr01792bopenalex-snapshot
Near-infrared nanosecond-pulsed laser-activated highly efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles
inferred← citeshttps://doi.org/10.1039/d0nr05067aopenalex-snapshot
Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells
inferred← citeshttps://doi.org/10.1039/d1bm00479dopenalex-snapshot
Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells
inferred← citeshttps://doi.org/10.1039/d1nj02062eopenalex-snapshot
Plasmonic carriers responsive to pulsed laser irradiation: a review of mechanisms, design, and applications
inferred← citeshttps://doi.org/10.1039/d1nr05461aopenalex-snapshot
Black phosphorus mediated photoporation: a broad absorption nanoplatform for intracellular delivery of macromolecules
inferred← citeshttps://doi.org/10.1039/d2lc00899hopenalex-snapshot
Metallic micro-ring device for highly efficient large cargo delivery in mammalian cells using infrared light pulses
inferred← citeshttps://doi.org/10.1039/d3lc00244fopenalex-snapshot
Ultrathin SU-8 membrane for highly efficient tunable cell patterning and massively parallel large biomolecular delivery
inferred← citeshttps://doi.org/10.1039/d4na00122bopenalex-snapshot
Nanoparticle-Mediated Photoporation: Expanding Horizons in Drug Delivery
inferred← citeshttps://doi.org/10.1039/d5cs00047eopenalex-snapshot
Laser-induced polymer dynamics and applications
inferred← citeshttps://doi.org/10.1039/d5ma01317hopenalex-snapshot
Immobilized, micro-patterned graphene nanoflake devices for high-throughput, uniform intracellular biomolecular delivery
inferred← citeshttps://doi.org/10.1063/5.0040331openalex-snapshot
Recent advances in bubble-based technologies: Underlying interaction mechanisms and applications
inferred← citeshttps://doi.org/10.1080/10717544.2024.2306231openalex-snapshot
A mini-review on gene delivery technique using nanoparticles-mediated photoporation induced by nanosecond pulsed laser
inferred← citeshttps://doi.org/10.1080/17425247.2021.1828340openalex-snapshot
Physical transfection technologies for macrophages and dendritic cells in immunotherapy
inferred← citeshttps://doi.org/10.1080/23746149.2016.1177468openalex-snapshot
Simulating the interaction of lipid membranes with polymer and ligand-coated nanoparticles
inferred← citeshttps://doi.org/10.1080/23746149.2016.1228476openalex-snapshot
Laser-assisted photoporation: fundamentals, technological advances and applications
inferred← citeshttps://doi.org/10.1088/1361-6439/aae5aeopenalex-snapshot
Single-cell electroporation: current trends, applications and future prospects
inferred← citeshttps://doi.org/10.1088/1361-6528/ab096bopenalex-snapshot
Advanced nanostructures for cell membrane poration
inferred← citeshttps://doi.org/10.1088/1361-6633/adedb3openalex-snapshot
Laser-induced plasma formation and cavitation in water: from nanoeffects to extreme states of matter
inferred← citeshttps://doi.org/10.1109/mems61431.2025.10917932openalex-snapshot
Micro-Flower Structure Activated Photoporation for Large Sized Biomolecular Delivery in Cancer Cells
inferred← citeshttps://doi.org/10.1109/nano.2015.7388709openalex-snapshot
Optical heating of metallic nanoparticles for fast injection of nanoscale sensor into living cells
inferred← citeshttps://doi.org/10.1109/nems50311.2020.9265617openalex-snapshot
Intracellular Delivery using Anisotropic Gold Nanocrystals Synthesized by Microfluidic Device
inferred← citeshttps://doi.org/10.1109/nems60219.2024.10639931openalex-snapshot
Controlled Synthesis of Branched Gold Nanoparticles By Microfluidic Device For Light-Activated Biomolecular Delivery
inferred← citeshttps://doi.org/10.1117/1.jbo.23.12.125002openalex-snapshot
Photoacoustic response induced by nanoparticle-mediated photothermal bubbles beyond the thermal expansion for potential theranostics
inferred← citeshttps://doi.org/10.1117/1.jbo.28.6.065006openalex-snapshot
Monitoring optoporated process on mammalian cells by real-time measurement of membrane resealing time
inferred← citeshttps://doi.org/10.1117/12.2075659openalex-snapshot
Efficient delivery of quantum dots in live cells by gold nanoparticle mediated photoporation
inferred← citeshttps://doi.org/10.1117/12.2077601openalex-snapshot
Laser transfection with gold nanoparticles: current state and new particle structures as a perspective
inferred← citeshttps://doi.org/10.1117/12.2079322openalex-snapshot
Experimental setup combining digital holographic microscopy (DHM) and fluorescence imaging to study gold nanoparticle mediated laser manipulation
inferred← citeshttps://doi.org/10.1117/12.2189552openalex-snapshot
Value added cleaning and disinfection of the root canal: laser-activated irrigation and laser-induced photoporation
inferred← citeshttps://doi.org/10.1117/12.2541844openalex-snapshot
Improving antibiotics' penetration and efficiency for treating biofilm infections by laser-induced vapor nanobubbles
inferred← citeshttps://doi.org/10.1117/12.2542160openalex-snapshot
VNB-mediated endosomal escape triggers robust gene silencing in human cell lines
inferred← citeshttps://doi.org/10.1126/sciadv.aeh0675openalex-snapshot
Converting lysosomes into photothermal organelles enables nanoparticle-free tumor ablation via intracellular vapor bubbles
inferred← citeshttps://doi.org/10.1177/13872877241289396openalex-snapshot
Progress of research and application of non-pharmacologic intervention in Alzheimer's disease
inferred← citeshttps://doi.org/10.1186/s12951-023-01797-3openalex-snapshot
Novel opto-fluidic drug delivery system for efficient cellular transfection
inferred← citeshttps://doi.org/10.1186/s12951-023-01935-xopenalex-snapshot
Spatiotemporally controlled drug delivery via photothermally driven conformational change of self-integrated plasmonic hybrid nanogels
inferred← citeshttps://doi.org/10.1186/s12951-025-03640-3openalex-snapshot
Pre-formation loading of extracellular vesicles with exogenous molecules using photoporation
inferred← citeshttps://doi.org/10.1186/s40580-022-00298-7openalex-snapshot
The cellular response to plasma membrane disruption for nanomaterial delivery
inferred← citeshttps://doi.org/10.1186/s40580-023-00409-yopenalex-snapshot
Upconverting-photon quenching-mediated perforation influx as an intracellular delivery method using posAuNP@UCNPs nanocomposites for osteoarthritis treatment
inferred← citeshttps://doi.org/10.1208/s12249-026-03524-1openalex-snapshot
Photothermally Induced Vapor Nanobubbles Enable Disruption and Antibiotic-Improved Responsiveness in Uropathogenic Biofilms
inferred← citeshttps://doi.org/10.1364/boe.10.003152openalex-snapshot
Gold nanoparticles in chemo-, immuno-, and combined therapy: review [Invited]
inferred← citeshttps://doi.org/10.1364/boe.8.004756openalex-snapshot
Analysis of poration-induced changes in cells from laser-activated plasmonic substrates
inferred← citeshttps://doi.org/10.1371/journal.pone.0124052openalex-snapshot
Investigation of Biophysical Mechanisms in Gold Nanoparticle Mediated Laser Manipulation of Cells Using a Multimodal Holographic and Fluorescence Imaging Setup
inferred← citeshttps://doi.org/10.14356/kona.2018011openalex-snapshot
Direct Permeation of Nanoparticles across Cell Membrane: A Review
inferred← citeshttps://doi.org/10.1515/nanoph-2019-0088openalex-snapshot
Multiresonant plasmonics with spatial mode overlap: overview and outlook
inferred← citeshttps://doi.org/10.1557/mrs.2019.107openalex-snapshot
Materials synthesis in a bubble
inferred← citeshttps://doi.org/10.21203/rs.3.rs-592826/v1openalex-snapshot
Gasdermin E-dependent and -independent Subroutines Regulate the Passage of Dextrans During Apoptosis-driven Secondary Necrosis.
inferred← citeshttps://doi.org/10.31917/2203204openalex-snapshot
Prospects for the use of small interfering RNAs as inhibitors of immune checkpoints for immunotherapy in oncology
inferred← citeshttps://doi.org/10.33320/maced.pharm.bull.2023.69.03.001openalex-snapshot
Exploring light for advanced drug delivery & surgery in the eye
inferred← citeshttps://doi.org/10.3389/fbioe.2022.973326openalex-snapshot
Delivering the CRISPR/Cas9 system for engineering gene therapies: Recent cargo and delivery approaches for clinical translation
inferred← citeshttps://doi.org/10.3389/fchem.2019.00179openalex-snapshot
Hierarchy of Hybrid Materials—The Place of Inorganics-in-Organics in it, Their Composition and Applications
inferred← citeshttps://doi.org/10.3389/fchem.2023.1078840openalex-snapshot
Hierarchy of hybrid materials. Part-II: The place of organics-on-inorganics in it, their composition and applications
inferred← citeshttps://doi.org/10.3389/fncel.2018.00080openalex-snapshot
Selective Labeling of Individual Neurons in Dense Cultured Networks With Nanoparticle-Enhanced Photoporation
inferred← citeshttps://doi.org/10.3390/cryst9080411openalex-snapshot
Gold Nanoparticle-Mediated Photoporation Enables Delivery of Macromolecules over a Wide Range of Molecular Weights in Human CD4+ T Cells
inferred← citeshttps://doi.org/10.3390/ijms19072006openalex-snapshot
Application of Nanoparticles for Targeting G Protein-Coupled Receptors
inferred← citeshttps://doi.org/10.3390/ijms19082400openalex-snapshot
Photothermally Triggered Endosomal Escape and Its Influence on Transfection Efficiency of Gold-Functionalized JetPEI/pDNA Nanoparticles
inferred← citeshttps://doi.org/10.3390/ijms19103143openalex-snapshot
Current Trends of Microfluidic Single-Cell Technologies
inferred← citeshttps://doi.org/10.3390/ijms20174254openalex-snapshot
Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells
inferred← citeshttps://doi.org/10.3390/ijms21041540openalex-snapshot
Surface Functionalization with Polyethylene Glycol and Polyethyleneimine Improves the Performance of Graphene-Based Materials for Safe and Efficient Intracellular Delivery by Laser-Induced Photoporation
inferred← citeshttps://doi.org/10.3390/ijms24043147openalex-snapshot
Response Surface Methodology to Efficiently Optimize Intracellular Delivery by Photoporation
inferred← citeshttps://doi.org/10.3390/membranes11080550openalex-snapshot
Delivery of Foreign Materials into Adherent Cells by Gold Nanoparticle-Mediated Photoporation
inferred← citeshttps://doi.org/10.3390/molecules23123157openalex-snapshot
Enhancements of Cancer Cell Damage Efficiencies in Photothermal and Photodynamic Processes through Cell Perforation and Preheating with Surface Plasmon Resonance of Gold Nanoring
inferred← citeshttps://doi.org/10.3390/pharmaceutics14081716openalex-snapshot
Photodisruption of the Inner Limiting Membrane: Exploring ICG Loaded Nanoparticles as Photosensitizers
inferred← citeshttps://doi.org/10.34133/bmr.0045openalex-snapshot
Recent Advancements in Biomaterials for Chimeric Antigen Receptor T Cell Immunotherapy
inferred← citeshttps://doi.org/10.4155/tde-2017-0049openalex-snapshot
Strategies in the Design of Gold Nanoparticles for Intracellular targeting: Opportunities and Challenges
inferred← citeshttps://doi.org/10.5101/nbe.v9i2.p129-134openalex-snapshot
The True Complexity of Photothermal Therapy: A Brief Perspective
inferred← citeshttps://doi.org/10.6084/m9.figshare.23520087openalex-snapshot
Additional file 1 of Spatiotemporally controlled drug delivery via photothermally driven conformational change of self-integrated plasmonic hybrid nanogels
inferred← citeshttps://doi.org/10.6084/m9.figshare.26660086openalex-snapshot
Additional file 1 of Upconverting-photon quenching-mediated perforation influx as an intracellular delivery method using posAuNP@UCNPs nanocomposites for osteoarthritis treatment
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