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The Role of Natural Product Chemistry in Drug Discovery

https://doi.org/10.1021/np040106y
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Surface-Initiated Polymerization for Amplification of Self-Assembled Monolayers Patterned by Microcontact Printing
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Natural Products as Leads for New Pharmaceuticals
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Drugs
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Combinatorial Synthesis of Small Organic Molecules
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Application and Limitations of X‐ray Crystallographic Data in Structure‐Based Ligand and Drug Design
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Gemtuzumab ozogamicin in the treatment of acute myeloid leukemia
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The History of Penicillin Production
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In Quest of Tomorrow’s Medicines
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Drug Discovery from Nature
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The Impact of Natural Products on Drug Discovery
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A Central Natural Product Pool — New Approach in Drug Discovery Strategies
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Automation Strategies in Drug Discovery
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Small Molecule — Protein Interactions
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Bioassay Methods in Natural Product Research and Drug Development
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Saponins in Food, Feedstuffs and Medicinal Plants
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Diversifying microbial natural products for drug discovery
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Enzymes in the synthesis of bioactive compounds
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The Process of Structure-Based Drug Design
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Rapid detection and identification of angiotensin-converting enzyme inhibitors by on-line liquid chromatography–biochemical detection, coupled to electrospray mass spectrometry
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Rapid dereplication of estrogenic compounds in pomegranate (Punica granatum) using on-line biochemical detection coupled to mass spectrometry
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The discovery and development of HMG-CoA reductase inhibitors.
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Protein-Protein Interactions
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Chapter 28. To market, to market — 2000
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Chapter 26. To market, to market - 2001
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Chapter 33. To market, to market - 2002
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Chapter 34. To Market, To Market - 1995
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NMR screening techniques in drug discovery and drug design
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Drug prototypes and their exploitation
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Drug prototypes and their exploitation
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Engineering secondary metabolite production in plants
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Will combinatorial chemistry deliver real medicines?
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Drugs, leads, and drug-likeness: an analysis of some recently launched drugs
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Toward High-Throughput Synthesis of Complex Natural Product-Like Compounds in the Genomics and Proteomics Age
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Pure compound libraries; a new perspective for natural product based drug discovery
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Structure-based screening of low-affinity compounds
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LC–NMR–MS in drug discovery
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The multiple orthogonal tools approach to define molecular causation in the validation of druggable targets
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The evolution of microarrayed compound screening
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The role of natural products in a modern drug discovery program
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Synthesis of natural-product-based compound libraries
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Modern methods to produce natural-product libraries
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Flow NMR applications in combinatorial chemistry
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Combinatorial biosynthesis of antimicrobials and other natural products
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Aquaculture of three phyla of marine invertebrates to yield bioactive metabolites: process developments and economics
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Emerging trends in high-throughput screening
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High-Throughput Method for the Production and Analysis of Large Natural Product Libraries for Drug Discovery
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High-Throughput Bioassay-Guided Fractionation: A Technique for Rapidly Assigning Observed Activity to Individual Components of Combinatorial Libraries, Screened in HTS Bioassays
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Distinguishing between Natural Products and Synthetic Molecules by Descriptor Shannon Entropy Analysis and Binary QSAR Calculations
inferredcites →https://doi.org/10.1021/ci000407nopenalex-snapshot
SENECA: A Platform-Independent, Distributed, and Parallel System for Computer-Assisted Structure Elucidation in Organic Chemistry
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Validation of Structural Proposals by Substructure Analysis and 13C NMR Chemical Shift Prediction
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Structure Elucidator: A Versatile Expert System for Molecular Structure Elucidation from 1D and 2D NMR Data and Molecular Fragments
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The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
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Mycophenolic Acid: A One Hundred Year Odyssey from Antibiotic to Immunosuppressant
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Calichemicins, a novel family of antitumor antibiotics. 2. Chemistry and structure of calichemicin .gamma.1I
inferredcites →https://doi.org/10.1021/ja00245a052openalex-snapshot
Reversible stereospecific extrusion of ethylene from a 1,2-diosmacyclobutane. Determination of stereochemistry by liquid-crystal NMR
inferredcites →https://doi.org/10.1021/jm010533yopenalex-snapshot
A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening
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Identification and Prediction of Promiscuous Aggregating Inhibitors among Known Drugs
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The Enediyne Antibiotics
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Choosing the Best Pulse Sequences, Acquisition Parameters, Postacquisition Processing Strategies, and Probes for Natural Product Structure Elucidation by NMR Spectroscopy
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Natural Products as Sources of New Drugs over the Period 1981−2002
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Stereochemistry of Kahalalide F
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A Chemical Screening Strategy for the Dereplication and Prioritization of HIV-Inhibitory Aqueous Natural Products Extracts
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Interference of Linoleic Acid Fraction in Some Receptor Binding Assays
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Natural products in drug discovery – Creating a new vision
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Curtain has fallen on hopes of legal bioprospecting
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Biodiversity law has had some unintended effects
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Designing screens: how to make your hits a hit
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A brief history of novel drug discovery technologies
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Enfuvirtide
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Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors
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News Analysis
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Enfuvirtide: the first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes
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Cutting the cost of drug development?
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The druggable genome
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Target selection in drug discovery
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LC-NMR: a new tool to expedite the dereplication and identification of natural products
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The influence of natural products upon drug discovery (Antiquity to late 1999)
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NMR-based methods and strategies for drug discovery
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Approaches to identify, clone, and express symbiont bioactive metabolite genes
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Natural product isolation
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The production of hypericins and hyperforin byin vitrocultures of St. John's wort (Hypericum perforatum)
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A functional genomics approach toward the understanding of secondary metabolism in plant cells
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The design, computer modeling, solution structure, and biological evaluation of synthetic analogs of bryostatin 1
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A Method for the Dereplication of Natural Product Extracts using Electrospray HPLC/MS
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APPLICATION OF CENTRIFUGAL PARTITION CHROMATOGRAPHY IN A GENERAL SEPARATION AND DEREPLICATION PROCEDURE FOR PLANT EXTRACTS
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SEPARATION OF CRUDE PLANT EXTRACTS WITH HIGH SPEED CCC FOR PRIMARY SCREENING IN DRUG DISCOVERY
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Methods in Molecular Biology
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Experimental Models of Primitive Cellular Compartments: Encapsulation, Growth, and Division
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Generating Diverse Skeletons of Small Molecules Combinatorially
inferredcites →https://doi.org/10.1126/science.287.5460.1960openalex-snapshot
Drug Discovery: A Historical Perspective
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Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery
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Mechanism-Based Target Identification and Drug Discovery in Cancer Research
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Microarray Compound Screening (μARCS) to Identify Inhibitors of HIV Integrase
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Development of a Plasmepsin II Fluorescence Polarization Assay Suitable for High Throughput Antimalarial Drug Discovery
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Screening of Natural Products Extracts for the Presence of Phosphodiesterase Inhibitors Using Liquid Chromatography Coupled Online to Parallel Biochemical Detection and Chemical Characterization
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Natural Products in High Throughput Screening: Automated High-Quality Sample Preparation
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Handbook of Drug Screening
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High Throughput Screening
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Bioactive Compounds from Natural Sources
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Finding the needle in the haystack. The dereplication of natural product extracts
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Molecular basis of biodiversity, conservation, and sustained innovative utilization (IUPAC Technical Report)
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Natural product-like combinatorial libraries
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Function Oriented Synthesis: The Design, Synthesis, PKC Binding and Translocation Activity of a New Bryostatin Analog
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The History of Penicillin Production
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Organic structure analysis
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Drugs: from discovery to approval
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Naturally-occurring .BETA.-lactamase inhibitors with antibacterial activity.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Antibacterial Natural Products in Medicinal Chemistry—Exodus or Revival?
inferred← citeshttps://doi.org/10.1002/anie.200602917openalex-snapshot
Domino Cu‐Catalyzed CN Coupling/Hydroamidation: A Highly Efficient Synthesis of Nitrogen Heterocycles
inferred← citeshttps://doi.org/10.1002/anie.201000775openalex-snapshot
On the Reach of Chemical Synthesis: Creation of a Mini‐Pipeline from an Academic Laboratory
inferred← citeshttps://doi.org/10.1002/anie.201005605openalex-snapshot
Gephyronic Acid, a Missing Link between Polyketide Inhibitors of Eukaryotic Protein Synthesis (Part II): Total Synthesis of Gephyronic Acid
inferred← citeshttps://doi.org/10.1002/anie.201710330openalex-snapshot
Transition‐Metal‐Catalyzed Selective Functionalization of C(sp3)−H Bonds in Natural Products
inferred← citeshttps://doi.org/10.1002/anie.201801299openalex-snapshot
Cyclic and Lasso Peptides: Sequence Determination, Topology Analysis, and Rotaxane Formation
inferred← citeshttps://doi.org/10.1002/anie.202202286openalex-snapshot
Investigation of the Molecular Landscape of Bacterial Aromatic Polyketides by Global Analysis of Type II Polyketide Synthases
inferred← citeshttps://doi.org/10.1002/anie.202212946openalex-snapshot
Thiamyxins: Structure and Biosynthesis of Myxobacterial RNA‐Virus Inhibitors**
inferred← citeshttps://doi.org/10.1002/aoc.4210openalex-snapshot
Current Applications of Suzuki–Miyaura Coupling Reaction in The Total Synthesis of Natural Products: An update
inferred← citeshttps://doi.org/10.1002/ardp.201400076openalex-snapshot
In VitroandIn SilicoStudies to Explore Structural Features of Flavonoids for Aldehyde Oxidase Inhibition
inferred← citeshttps://doi.org/10.1002/ardp.202100123openalex-snapshot
Garcinol from Garcinia indica inhibits HIV‐1 reverse transcriptase‐associated ribonuclease H
inferred← citeshttps://doi.org/10.1002/asia.200800445openalex-snapshot
Total Synthesis of (−)‐Spirangien A, an Antimitotic Polyketide Isolated from the Myxobacterium Sorangium Cellulosum
inferred← citeshttps://doi.org/10.1002/asia.200800448openalex-snapshot
Efficient Synthesis of the Deoxysugar Part of Versipelostatin by Direct and Stereoselective Glycosylation and Revision of the Structure of the Trisaccharide Unit
inferred← citeshttps://doi.org/10.1002/asia.200900640openalex-snapshot
Combinatorial Synthesis of Deoxyhexasaccharides Related to the Landomycin A Sugar Moiety, Based on an Orthogonal Deprotection Strategy
inferred← citeshttps://doi.org/10.1002/asia.202100277openalex-snapshot
Alkyl Enol Ethers: Development in Intermolecular Organic Transformation
inferred← citeshttps://doi.org/10.1002/asia.202101123openalex-snapshot
A Carbohydrate‐based Synthetic Approach to Diverse Structurally and Stereochemically Complex Chiral Polyheterocycles
inferred← citeshttps://doi.org/10.1002/biof.115openalex-snapshot
Phytochemicals and adipogenesis
inferred← citeshttps://doi.org/10.1002/biot.202300324openalex-snapshot
Boosting production of cembratriene‐ol in Saccharomyces cerevisiae via systematic optimization
inferred← citeshttps://doi.org/10.1002/cbdv.200690092openalex-snapshot
Relationships between Inhibitory Activity against a Cancer Cell Line Panel, Profiles of Plants Collected, and Compound Classes Isolated in an Anticancer Drug Discovery Project
inferred← citeshttps://doi.org/10.1002/cbdv.200800082openalex-snapshot
Chemical and Pharmacological Aspects of the Genus Calophyllum
inferred← citeshttps://doi.org/10.1002/cbdv.201000264openalex-snapshot
Evaluation of the Antimicrobial Potential of Two Flavonoids Isolated from Limnophila Plants
inferred← citeshttps://doi.org/10.1002/cbdv.201900366openalex-snapshot
Chemical and Biological Aspects of Garcinol and Isogarcinol: Recent Developments
inferred← citeshttps://doi.org/10.1002/cbdv.202100292openalex-snapshot
Platanic Acid‐Aryl Enones as Potential Anticancer Compounds: Synthesis and Biological Profiling against Breast, Prostate and Lung Cancer Cell Lines
inferred← citeshttps://doi.org/10.1002/cbdv.202100542openalex-snapshot
An Update on Natural Antileishmanial Treatment Options from Plants, Fungi and Algae
inferred← citeshttps://doi.org/10.1002/cbdv.202300649openalex-snapshot
Chemical Composition, Antimicrobial, Nitric Oxide Inhibition and Cytotoxic Activity of Essential Oils from Zanthoxylum acanthopodium DC. Leaves and Stems from Vietnam
inferred← citeshttps://doi.org/10.1002/cbdv.202300843openalex-snapshot
Synthesis of Novel Pyrazole‐Oxindole Conjugates with Cytotoxicity in Human Cancer Cells via Apoptosis
inferred← citeshttps://doi.org/10.1002/cbdv.202301508openalex-snapshot
Antinociceptive Effect of Dillenia indica (Linn.) Mediated by Opioid and Cannabinoid Systems: Pharmacological and Chemical Studies
inferred← citeshttps://doi.org/10.1002/cbdv.202503447openalex-snapshot
Ziziphus budhensis Seed Extracts: Phytoconstituents and Preliminary In Vitro and In Vivo Biological Activities
inferred← citeshttps://doi.org/10.1002/cbdv.71149openalex-snapshot
Computational Discovery of CDK8 Inhibitors From Natural Compounds in NPACT Database
inferred← citeshttps://doi.org/10.1002/cbdv.71535openalex-snapshot
Plant‐Based Therapeutics Against Communicable Diseases: A Review of Ethnopharmacology and Medicinal Chemistry Approaches
inferred← citeshttps://doi.org/10.1002/chem.200600599openalex-snapshot
Total Synthesis of the Cyclodepsipeptide Apratoxin A and Its Analogues and Assessment of Their Biological Activities
inferred← citeshttps://doi.org/10.1002/chem.200800292openalex-snapshot
Chemical Defence Strategies of Higher Fungi
inferred← citeshttps://doi.org/10.1002/chem.201002942openalex-snapshot
Broadening Deoxysugar Glycodiversity: Natural and Engineered Transaldolases Unlock a Complementary Substrate Space
inferred← citeshttps://doi.org/10.1002/chem.201101037openalex-snapshot
Negishi Cross‐Coupling Reactions Catalyzed by an Aminophosphine‐Based Nickel System: A Reliable and General Applicable Reaction Protocol for the High‐Yielding Synthesis of Biaryls
inferred← citeshttps://doi.org/10.1002/chem.201202222openalex-snapshot
Cyclohexyne Cycloinsertion in the Divergent Synthesis of Guanacastepenes
inferred← citeshttps://doi.org/10.1002/chem.201404479openalex-snapshot
Visible‐Light Promoted Catalyst‐Free Imidation of Arenes and Heteroarenes
inferred← citeshttps://doi.org/10.1002/chem.201703094openalex-snapshot
Regiodivergent Remote Arylation of Cycloalkanols to Dysideanone′s Fused Carbotetracycles and Its Bridged Isomers
inferred← citeshttps://doi.org/10.1002/chem.201905385openalex-snapshot
Cyclic Peptides as Drugs for Intracellular Targets: The Next Frontier in Peptide Therapeutic Development
inferred← citeshttps://doi.org/10.1002/chem.202003209openalex-snapshot
A Serendipitous One‐Pot Cyanation/Hydrolysis/Enamide Formation: Direct Access to 3‐Methyleneisoindolin‐1‐ones
inferred← citeshttps://doi.org/10.1002/chin.200802260openalex-snapshot
ChemInform Abstract: In Search of Novel Antibiotics Using a Natural Product Template Approach
inferred← citeshttps://doi.org/10.1002/cjoc.202000214openalex-snapshot
DMAP‐Catalyzed C—N Bond Formation for Diverse Synthesis of Imidazo[1,2‐a]pyrimidine and Pyrimido[1,2‐a]benzimidazole Derivatives
inferred← citeshttps://doi.org/10.1002/cmdc.201300273openalex-snapshot
Structural Elaboration of a Natural Product: Identification of 3,3′‐Diindolylmethane Aminophosphonate and Urea Derivatives as Potent Anticancer Agents
inferred← citeshttps://doi.org/10.1002/cmdc.201500138openalex-snapshot
Biocatalysis at Work: Applications in the Development of Sagopilone
inferred← citeshttps://doi.org/10.1002/cmdc.201800343openalex-snapshot
What Has Come out from Phytomedicines and Herbal Edibles for the Treatment of Cancer?
inferred← citeshttps://doi.org/10.1002/cssc.201600801openalex-snapshot
d ‐Glucose: An Efficient Reducing Agent for a Copper(II)‐Mediated Arylation of Primary Amines in Water
inferred← citeshttps://doi.org/10.1002/ddr.10389openalex-snapshot
A new model for utilising chemical diversity from natural sources
inferred← citeshttps://doi.org/10.1002/ejoc.200500911openalex-snapshot
Palladium‐Catalysed Cross‐Coupling and Related Reactions Involving Pyrroles
inferred← citeshttps://doi.org/10.1002/ejoc.201200679openalex-snapshot
Copper‐Catalyzed Decarboxylative Three‐Component Reactions for the Synthesis of Imidazo[1,2‐a]pyridines
inferred← citeshttps://doi.org/10.1002/ejoc.201201155openalex-snapshot
Stereodivergent Total Synthesis of (+)‐Aspergillide B and (+)‐7‐epi‐Aspergillide A
inferred← citeshttps://doi.org/10.1002/ejoc.201201220openalex-snapshot
Alkaloids from the Sponge‐Associated Fungus Aspergillus sp.
inferred← citeshttps://doi.org/10.1002/ejoc.201400006openalex-snapshot
Iterative α‐Glycosylation Strategy for 2‐Deoxy‐ and 2,6‐Dideoxysugars: Application to the One‐Pot Synthesis of Deoxysugar‐Containing Oligosaccharides
inferred← citeshttps://doi.org/10.1002/ejoc.201402021openalex-snapshot
Efficient Synthesis of Dihydropyrazoles by Halocyclization of β,γ‐Unsaturated Hydrazones
inferred← citeshttps://doi.org/10.1002/ejoc.201500515openalex-snapshot
Reagent Control of a Birch Reduction for the Synthesis of a 2‐Deoxyoligosaccharide Possessing a 1,4‐Dialkylhydroquinone
inferred← citeshttps://doi.org/10.1002/ejoc.201501017openalex-snapshot
Regioselective [1N+2C+2C] Assembly of Fully Decorated Pyrroles from Primary Amines, 1,2‐Diaza‐1,3‐dienes, and 2,3‐Allenoates
inferred← citeshttps://doi.org/10.1002/ejoc.201901665openalex-snapshot
The Potential of β‐Hydroxy‐γ‐vinyl‐γ‐lactone in the Synthesis of Natural Products and Beyond
inferred← citeshttps://doi.org/10.1002/ejoc.202001246openalex-snapshot
Evolution of Strategies in Protecting‐Group‐Free Synthesis of Natural Products: A Recent Update
inferred← citeshttps://doi.org/10.1002/ejoc.202300985openalex-snapshot
Organocatalyzed Kinetic Resolution of Racemic Carboxylic Acids
inferred← citeshttps://doi.org/10.1002/hlca.200790242openalex-snapshot
A Novel ‘Domino‐Click Approach’ to Unsymmetrical Bis‐1H‐1,2,3‐triazoles
inferred← citeshttps://doi.org/10.1002/hlca.201200216openalex-snapshot
A Novel and Efficient Synthesis of 3‐[(4,5‐Dihydro‐1H‐pyrrol‐3‐yl)carbonyl]‐2H‐chromen‐2‐ones (=3‐[(4,5‐Dihydro‐1H‐pyrrol‐3‐yl)carbonyl]‐2H‐1‐benzopyran‐2‐ones)
inferred← citeshttps://doi.org/10.1002/ijc.31965openalex-snapshot
Therapeutic value of steroidal alkaloids in cancer: Current trends and future perspectives
inferred← citeshttps://doi.org/10.1002/iub.2762openalex-snapshot
Lobeline: A multifunctional alkaloid modulates cholinergic and glutamatergic activities
inferred← citeshttps://doi.org/10.1002/jhet.1756openalex-snapshot
Synthesis of 2‐Oxopyrrole‐fused 1,n‐Diazaheterocyclic Compounds and Substituted 2‐Oxopyrroles via a Three‐Component Reaction
inferred← citeshttps://doi.org/10.1002/jhet.4331openalex-snapshot
Synthesis and bioactivity evaluation of eugenol hybrids obtained by Mannich and 1,3 dipolar cycloaddition reactions
inferred← citeshttps://doi.org/10.1002/jhet.4332openalex-snapshot
Synthesis of non‐toxic anticancer active forskolin‐indole‐triazole conjugates along with their in silico succinate dehydrogenase inhibition studies
inferred← citeshttps://doi.org/10.1002/jssc.201000045openalex-snapshot
Screening of antioxidant phenolic compounds in Chinese Rhubarb combining fast counter‐current chromatography fractionation and liquid chromatography/mass spectrometry analysis
inferred← citeshttps://doi.org/10.1002/jssc.201300917openalex-snapshot
Separation and purification of antioxidants from Ampelopsis heterophylla by counter‐current chromatography
inferred← citeshttps://doi.org/10.1002/jssc.201501016openalex-snapshot
Five‐descriptor model to predict the chromatographic sequence of natural compounds
inferred← citeshttps://doi.org/10.1002/macp.202500265openalex-snapshot
Synthesis and Properties of Curcumin‐Based Phosphorus Containing Intrinsic Flame‐Retardant Epoxy Resin
inferred← citeshttps://doi.org/10.1002/med.21351openalex-snapshot
Natural Product Inspired N‐Terminal Hsp90 Inhibitors: From Bench to Bedside?
inferred← citeshttps://doi.org/10.1002/med.21423openalex-snapshot
Marine Mollusk‐Derived Agents with Antiproliferative Activity as Promising Anticancer Agents to Overcome Chemotherapy Resistance
inferred← citeshttps://doi.org/10.1002/mnfr.201100270openalex-snapshot
Turmeric ( Curcuma longa ) inhibits inflammatory nuclear factor (NF)‐κB and NF‐κB‐regulated gene products and induces death receptors leading to suppressed proliferation, induced chemosensitization, and suppressed osteoclastogenesis
inferred← citeshttps://doi.org/10.1002/moda.3openalex-snapshot
Modern and future forestry based on biotechnology
inferred← citeshttps://doi.org/10.1002/mrc.1984openalex-snapshot
Synthesis and spectroscopic characterisation of a combinatorial library based on the fungal natural product 3‐chloro‐4‐hydroxyphenylacetamide
inferred← citeshttps://doi.org/10.1002/pca.1255openalex-snapshot
Analysis of nordihydroguaiaretic acid in Larrea divaricata Cav. extracts by micellar electrokinetic chromatography
inferred← citeshttps://doi.org/10.1002/pca.3010openalex-snapshot
NMR‐based screening for natural product subfraction to precisely identify ligand of target protein
inferred← citeshttps://doi.org/10.1002/psc.2538openalex-snapshot
A novel glucagon‐like peptide 1 peptide identified from Ophisaurus harti
inferred← citeshttps://doi.org/10.1002/ptr.2248openalex-snapshot
Antitumor activity of Hypericum hookerianum against DLA induced tumor in mice and its possible mechanism of action
inferred← citeshttps://doi.org/10.1002/ptr.2873openalex-snapshot
Inhibitory effects on bacterial growth and b‐ketoacyl‐ACP reductase by different species of maple leaf extracts and tannic acid
inferred← citeshttps://doi.org/10.1002/ptr.3258openalex-snapshot
Metabolomics for bioactivity assessment of natural products
inferred← citeshttps://doi.org/10.1002/ptr.3678openalex-snapshot
Antiproliferative Activity of Flavonoids: Influence of the Sequential Methoxylation State of the Flavonoid Structure
inferred← citeshttps://doi.org/10.1002/ptr.5428openalex-snapshot
Mangosenone F, A Furanoxanthone from Garciana mangostana, Induces Reactive Oxygen Species‐Mediated Apoptosis in Lung Cancer Cells and Decreases Xenograft Tumor Growth
inferred← citeshttps://doi.org/10.1002/ptr.5669openalex-snapshot
Natural Products as Mechanism‐based Anticancer Agents: Sp Transcription Factors as Targets
inferred← citeshttps://doi.org/10.1002/ptr.5933openalex-snapshot
Current Status of Herbal Drug Standards in the Indian Pharmacopoeia
inferred← citeshttps://doi.org/10.1002/ptr.6030openalex-snapshot
F1012‐2 inhibits the growth of triple negative breast cancer through induction of cell cycle arrest, apoptosis, and autophagy
inferred← citeshttps://doi.org/10.1002/ptr.7099openalex-snapshot
Natural products: A lead for drug discovery and development
inferred← citeshttps://doi.org/10.1002/qua.24205openalex-snapshot
Inverse virtual screening studies of selected natural compounds from cerrado
inferred← citeshttps://doi.org/10.1002/rcm.8450openalex-snapshot
Characterization of curcumin metabolites in rats by ultra‐high‐performance liquid chromatography with electrospray ionization quadrupole time‐of‐flight tandem mass spectrometry
inferred← citeshttps://doi.org/10.1002/slct.201600907openalex-snapshot
Identification of Anticancer Drug Candidate Targeting Nuclear Receptor Retinoid X receptor‐α from Natural Products using Receptor‐Ligand Recognition
inferred← citeshttps://doi.org/10.1002/slct.201601613openalex-snapshot
Methyl 1,2‐Orthoesters in Acid‐Washed Molecular Sieves Mediated Glycosylations
inferred← citeshttps://doi.org/10.1002/slct.201701870openalex-snapshot
Mild Thio‐Diversification of Bioactive Natural Products. Withaferin A: A Case study.
inferred← citeshttps://doi.org/10.1002/slct.201702875openalex-snapshot
Copper‐Catalyzed Stereoselective Domino Synthesis of ( Z )‐3‐Methyleneisoindolin‐1‐one
inferred← citeshttps://doi.org/10.1002/slct.201800397openalex-snapshot
A Ligand/Additive/Base‐Free C(sp 2 )‐H Activation and Isocyanide Insertion in PEG‐400: Synthesis of Indolizine/Imidazoline‐Fused Heterocycles
inferred← citeshttps://doi.org/10.1002/slct.202102760openalex-snapshot
Synthesis of New 4‐Vinyl‐1,2,3‐Thiadiazoles
inferred← citeshttps://doi.org/10.1002/slct.202200592openalex-snapshot
A New Zinc‐Based Metal‐Organic Framework for Catalytic Synthesis of N ‐Substituted Pyrroles
inferred← citeshttps://doi.org/10.1002/slct.202400554openalex-snapshot
Semisynthesis: An Essential Tool for Antibiotics Drug Discovery
inferred← citeshttps://doi.org/10.1002/slct.202402092openalex-snapshot
Bioactive Compounds from Achyranthes Aspera L. Extract: A UHPLC Profile and In Silico Study for Mouth Cancer
inferred← citeshttps://doi.org/10.1002/tcr.201600020openalex-snapshot
Transition Metal-Participated Synthesis and Utilization of N-containing Heterocycles: Exploring for Nitrogen Sources
inferred← citeshttps://doi.org/10.1002/vjch.201900108openalex-snapshot
Bioactive compounds from marine Streptomyces sp.: Structure identification and biological activities
inferred← citeshttps://doi.org/10.1002/vjch.202100108openalex-snapshot
Flavonoids as potential agents for development of multi‐target drugs for covid‐19 treatment: An in silico study
inferred← citeshttps://doi.org/10.1007/128_2006_107openalex-snapshot
Combinatorial Solid-Phase Natural Product Chemistry
inferred← citeshttps://doi.org/10.1007/4243_2018_1openalex-snapshot
Fluorescence in Pharmaceutics and Cosmetics
inferred← citeshttps://doi.org/10.1007/978-0-387-76678-2_2openalex-snapshot
Drug Discovery From Natural Sources
inferred← citeshttps://doi.org/10.1007/978-0-387-85498-4_24openalex-snapshot
Plant-derived natural products as leads for drug discovery
inferred← citeshttps://doi.org/10.1007/978-1-0716-2716-7_5openalex-snapshot
Mass Spectroscopy as an Analytical Tool to Harness the Production of Secondary Plant Metabolites: The Way Forward for Drug Discovery
inferred← citeshttps://doi.org/10.1007/978-1-4614-1400-1_25openalex-snapshot
Natural Products in the 21st Century
inferred← citeshttps://doi.org/10.1007/978-1-60761-244-5_17openalex-snapshot
A Natural Products Approach to Drug Discovery: Probing Modes of Action of Antitumor Agents by Genome-Scale cDNA Library Screening
inferred← citeshttps://doi.org/10.1007/978-1-61779-624-1_20openalex-snapshot
Natural Products Isolation in Modern Drug Discovery Programs
inferred← citeshttps://doi.org/10.1007/978-3-030-02622-6_1openalex-snapshot
Exploration of Macrofungi in Sub-Tropical Semi-Evergreen Indian Forest Ecosystems
inferred← citeshttps://doi.org/10.1007/978-3-030-39793-7_10openalex-snapshot
Threatened Medicinal Plants in the Western Ghats – Phytochemical Perspective
inferred← citeshttps://doi.org/10.1007/978-3-030-39793-7_12openalex-snapshot
Drugs From Threatened Medicinal Plants
inferred← citeshttps://doi.org/10.1007/978-3-030-74326-0_3openalex-snapshot
Nature’s Generosity in Protecting Human Health
inferred← citeshttps://doi.org/10.1007/978-3-030-74326-0_4openalex-snapshot
Biodiversity and Drug Discovery Approach to Natural Medicine
inferred← citeshttps://doi.org/10.1007/978-3-030-85222-1_1openalex-snapshot
Introduction
inferred← citeshttps://doi.org/10.1007/978-3-031-21973-3_31-1openalex-snapshot
Herbal Medicine for Health Management and Disease Prevention
inferred← citeshttps://doi.org/10.1007/978-3-031-28780-0_32openalex-snapshot
Biochanin A Chemistry, Structural Modifications, and Therapeutic Applications: An Update
inferred← citeshttps://doi.org/10.1007/978-3-031-35221-8_15openalex-snapshot
A Review on the Golden Plant Turmeric and Its Bioactive Compound Curcumin
inferred← citeshttps://doi.org/10.1007/978-3-031-43199-9_31openalex-snapshot
Herbal Medicine for Health Management and Disease Prevention
inferred← citeshttps://doi.org/10.1007/978-3-031-97837-1_7openalex-snapshot
Promoting Traditional Medicine, Sustainability, and Internationalisation in Higher Education: The Case of Yaoundé-Bielefeld Bilateral Graduate School of Natural Products with Antiparasital and Antibacterial Activities (YaBiNaPA)
inferred← citeshttps://doi.org/10.1007/978-3-032-23507-7_12openalex-snapshot
Fungal Secondary Metabolites in Drug Discovery and Development
inferred← citeshttps://doi.org/10.1007/978-3-211-78207-1_4openalex-snapshot
Semisynthetic Derivatives of Epothilones
inferred← citeshttps://doi.org/10.1007/978-3-319-41334-1_17openalex-snapshot
Butein and Its Role in Chronic Diseases
inferred← citeshttps://doi.org/10.1007/978-3-319-47935-4_8openalex-snapshot
Iwokrama Fungal/Plant Bioprospecting Project 2000–2003 – A Model for the Future?
inferred← citeshttps://doi.org/10.1007/978-3-319-53112-0_8openalex-snapshot
Transformation of Natural Products into Synthetic Copolymers
inferred← citeshttps://doi.org/10.1007/978-3-319-54102-0_6openalex-snapshot
Antidiabetic Medicinal Plants
inferred← citeshttps://doi.org/10.1007/978-3-319-63862-1_1openalex-snapshot
Introduction
inferred← citeshttps://doi.org/10.1007/978-3-319-63862-1_3openalex-snapshot
Medicinal, Non-medicinal, Biopesticides, Color- and Dye-Yielding Plants; Secondary Metabolites and Drug Principles; Significance of Medicinal Plants; Use of Medicinal Plants in the Systems of Traditional and Complementary and Alternative Medicines (CAMs)
inferred← citeshttps://doi.org/10.1007/978-3-319-68717-9_1openalex-snapshot
Importance of Medicinal and Aromatic Plants in Human Life
inferred← citeshttps://doi.org/10.1007/978-3-319-69075-9_3openalex-snapshot
Anti-infective Compounds from Marine Organisms
inferred← citeshttps://doi.org/10.1007/978-3-319-71740-1_11openalex-snapshot
Cyclic Peptides and Depsipeptides from Fungi
inferred← citeshttps://doi.org/10.1007/978-3-319-93506-5_1openalex-snapshot
The Search for Anticancer Agents from Tropical Plants
inferred← citeshttps://doi.org/10.1007/978-3-319-93997-1_4openalex-snapshot
Ethnobotany and Pharmacological Uses of Elaeocarpus floribundus Blume (Elaeocarpaceae)
inferred← citeshttps://doi.org/10.1007/978-3-319-99602-8_12openalex-snapshot
Drug Discovery: A Biodiversity Perspective
inferred← citeshttps://doi.org/10.1007/978-3-540-34281-6_7openalex-snapshot
Das medizinische Potential von Pflanzenstoffen
inferred← citeshttps://doi.org/10.1007/978-3-540-74603-4_1openalex-snapshot
Drug Discovery from Plants
inferred← citeshttps://doi.org/10.1007/978-3-642-00286-1_13openalex-snapshot
Cyclic Peptides and Depsipeptides from Fungi
inferred← citeshttps://doi.org/10.1007/978-3-642-11458-8_6openalex-snapshot
Non-β-Lactam Antibiotics
inferred← citeshttps://doi.org/10.1007/978-3-642-19382-8_7openalex-snapshot
Marine Organisms and Their Prospective Use in Therapy of Human Diseases
inferred← citeshttps://doi.org/10.1007/978-3-642-33823-6_18openalex-snapshot
Medicinal Aspects of Edible Ectomycorrhizal Mushrooms
inferred← citeshttps://doi.org/10.1007/978-3-642-36202-6_251-1openalex-snapshot
Advanced Approaches in the Discovery and Analysis of Natural Products and their Uses as Potential Therapeutic Agents
inferred← citeshttps://doi.org/10.1007/978-3-642-38076-1_8openalex-snapshot
Antifungal Metabolites of Endophytic Fungi
inferred← citeshttps://doi.org/10.1007/978-3-642-41787-0_10openalex-snapshot
Plant Compounds Acting on the Cytoskeleton
inferred← citeshttps://doi.org/10.1007/978-3-662-48520-0_7openalex-snapshot
Leaching of Active Ingredients from Plants with Ionic Liquids
inferred← citeshttps://doi.org/10.1007/978-3-7643-7567-6_5openalex-snapshot
Elucidating the mode-of-action of compounds from metabolite profiling studies
inferred← citeshttps://doi.org/10.1007/978-3-7643-8117-2_1openalex-snapshot
Mother Nature’s gifts to diseases of man: the impact of natural products on anti-infective, anticholestemics and anticancer drug discovery
inferred← citeshttps://doi.org/10.1007/978-3-7643-8338-1_5openalex-snapshot
Toxic plants: a chemist’s perspective
inferred← citeshttps://doi.org/10.1007/978-3-7643-8595-8_2openalex-snapshot
Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin
inferred← citeshttps://doi.org/10.1007/978-81-322-2794-6_10openalex-snapshot
Bioactive Potential of Sponge Secondary Metabolites
inferred← citeshttps://doi.org/10.1007/978-90-481-3002-3_15openalex-snapshot
Marine Drugs Development and Social Implication
inferred← citeshttps://doi.org/10.1007/978-94-017-9810-5_3openalex-snapshot
Chemical Diversity of Medicinal Plants
inferred← citeshttps://doi.org/10.1007/978-981-10-1085-9_12openalex-snapshot
Pharmacokinetics of Phytopharmaceuticals: A Peek into Contingencies and Impediments in Herbal Drug Development
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