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Antimalarial Activity of Physalins B, D, F, and G

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ptr.1196openalex-snapshot
Evaluation of efficacy and safety of a herbal medicine used for the treatment of malaria
inferredcites →https://doi.org/10.1016/0031-9422(80)83078-0openalex-snapshot
New physalins from Physalis angulata and Physalis lancifolia. Structure and reactions of physalins D, I, G and K
inferredcites →https://doi.org/10.1016/j.bmcl.2003.12.069openalex-snapshot
Antimalarial activity of phenazines from lapachol, β-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo
inferredcites →https://doi.org/10.1016/j.ejphar.2006.11.061openalex-snapshot
Enhanced activity of mefloquine and artesunic acid against Plasmodium falciparum in vitro and P. berghei in mice by combination with ciprofloxacin
inferredcites →https://doi.org/10.1016/j.intimp.2005.09.007openalex-snapshot
Physalins B, F and G, seco-steroids purified from Physalis angulata L., inhibit lymphocyte function and allogeneic transplant rejection
inferredcites →https://doi.org/10.1016/s0014-2999(02)02829-7openalex-snapshot
Inhibition of macrophage activation and lipopolysaccaride-induced death by seco-steroids purified from Physalis angulata L.
inferredcites →https://doi.org/10.1016/s0031-9422(00)94201-8openalex-snapshot
De novo synthesis of acetylcholinesterase in roots of Pisum sativum
inferredcites →https://doi.org/10.1021/j100155a036openalex-snapshot
Single-photon and multiphoton dissociation of molybdenum hexacarbonyl at 248 nm
inferredcites →https://doi.org/10.1021/j100171a026openalex-snapshot
Evaluation of vibrational force fields derived by using semiempirical and ab initio methods
inferredcites →https://doi.org/10.1021/np900691wopenalex-snapshot
Activity of Physalin F in a Collagen-Induced Arthritis Model
inferredcites →https://doi.org/10.1038/nbt1284openalex-snapshot
Relating protein pharmacology by ligand chemistry
inferredcites →https://doi.org/10.1038/sj.bjp.0706321openalex-snapshot
Mechanisms of the anti‐inflammatory effects of the natural secosteroids physalins in a model of intestinal ischaemia and reperfusion injury
inferredcites →https://doi.org/10.1055/s-0028-1097339openalex-snapshot
Physalin D, a New 13, 14–Seco–16, 24–Cyclo Steroid from Physalis minima
inferredcites →https://doi.org/10.1078/094471103322331458openalex-snapshot
Cytotoxic activity of some lichen extracts on murine and human cancer cell lines
inferredcites →https://doi.org/10.1093/jac/dkp170openalex-snapshot
Activity of physalins purified from Physalis angulata in in vitro and in vivo models of cutaneous leishmaniasis
inferredcites →https://doi.org/10.1128/cvi.00058-08openalex-snapshot
Biological Activities of Anti-Merozoite Surface Protein-1 Antibodies Induced by Adjuvant-Assisted Immunizations in Mice with Different Immune Gene Knockouts
inferredcites →https://doi.org/10.1211/jpp.58.2.0011openalex-snapshot
In-vitro and in-vivo antitumour activity of physalins B and D from Physalis angulata
inferredcites →https://doi.org/10.1248/bpb.27.193openalex-snapshot
Trypanocidal Constituents in Plants: 4. Withanolides from the Aerial Parts of Physalis angulata
inferredcites →https://doi.org/10.1248/cpb.54.1226openalex-snapshot
Trypanocidal Constituents in Plants 6. Minor Withanolides from the Aerial Parts of Physalis angulata
inferredcites →https://doi.org/10.1590/s0074-02761999000600017openalex-snapshot
Antimalarial drug susceptibility testing of Plasmodium falciparum in Brazil using a radioisotope method
inferredcites →https://doi.org/10.1645/0022-3395(2005)091[0484:hmpicc]2.0.co;2openalex-snapshot
Human Malaria Parasites in Continuous Culture
inferredcites →https://doi.org/10.2174/138945008786949379openalex-snapshot
Drug-Binding Databases
inferredcites →https://doi.org/10.4269/ajtmh.1998.58.630openalex-snapshot
Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2021.112925zenodo-depositor-declared
Naturally occurring physalins from the genus Physalis: A review
inferred← citeshttps://doi.org/10.1002/cbdv.201400435openalex-snapshot
Chemical Constituents and Biological Activities of Plants from the Genus Physalis
inferred← citeshttps://doi.org/10.1002/jcp.27537openalex-snapshot
Physalin D regulates macrophage M1/M2 polarization via the STAT1/6 pathway
inferred← citeshttps://doi.org/10.1002/jssc.201701089openalex-snapshot
Simultaneous pharmacokinetics and stability studies of physalins in rat plasma and intestinal bacteria culture media using liquid chromatography with mass spectrometry
inferred← citeshttps://doi.org/10.1002/vjch.2019000133openalex-snapshot
The anti‐microbial activities of secosteroids isolated from Physalis angulata
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_1openalex-snapshot
A Primer on SAnDReS 2.0 for Scoring Function Design
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_10openalex-snapshot
Molegro Virtual Docker for Docking Screens
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_11openalex-snapshot
Molegro Data Modeller for Machine Learning
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_12openalex-snapshot
Neural Networks with Molegro Data Modeller
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_13openalex-snapshot
AlphaFold for Docking Screens
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_14openalex-snapshot
Differential Evolution for Docking Simulations
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_15openalex-snapshot
Machine Learning to Predict CDK4 Inhibition
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_16openalex-snapshot
Targeting CDK9 with Molegro Virtual Docker
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_17openalex-snapshot
CDK7 as a Target for Docking Screens
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_18openalex-snapshot
Molegro Data Modeller to Estimate CDK6 Inhibition
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_19openalex-snapshot
Neural Networks to Calculate CDK2 Inhibition
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_20openalex-snapshot
Tree-Based Methods to Predict Enzyme Inhibition
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_3openalex-snapshot
Combining MVD and Ridge Method to Predict CDK2 Inhibition
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_4openalex-snapshot
Elastic Net Regression to Predict CDK2 Inhibition
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_5openalex-snapshot
Gradient Descent to Predict Enzyme Inhibition
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_7openalex-snapshot
Calculating Enzyme Inhibition with Random Forests
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_8openalex-snapshot
Extremely Randomized Trees to Determine Binding Affinity
inferred← citeshttps://doi.org/10.1007/978-1-0716-4949-7_9openalex-snapshot
Hands-On Docking with Molegro Virtual Docker
inferred← citeshttps://doi.org/10.1007/978-1-4939-9752-7_10openalex-snapshot
Molegro Virtual Docker for Docking
inferred← citeshttps://doi.org/10.1007/978-1-4939-9752-7_3openalex-snapshot
How Docking Programs Work
inferred← citeshttps://doi.org/10.1007/978-1-4939-9752-7_9openalex-snapshot
Docking with AutoDock4
inferred← citeshttps://doi.org/10.1007/978-3-030-14632-0_3openalex-snapshot
A Toolbox for the Identification of Modes of Action of Natural Products
inferred← citeshttps://doi.org/10.1007/978-3-030-14632-0_5openalex-snapshot
Cheminformatic Analysis of Natural Product Fragments
inferred← citeshttps://doi.org/10.1007/978-3-319-67045-4_10openalex-snapshot
Antimalarial Terpenic Compounds Isolated from Plants Used in Traditional Medicine (2010–July 2016)
inferred← citeshttps://doi.org/10.1007/978-94-007-5628-1_34openalex-snapshot
Physalis angulata
inferred← citeshttps://doi.org/10.1007/s00210-026-05354-1openalex-snapshot
Physalis minima L.: A comprehensive review on phytochemistry, pharmacology, and food applications
inferred← citeshttps://doi.org/10.1007/s10298-017-1183-3openalex-snapshot
Alkékenge : Physalis alkekengi L. (Solanaceae)
inferred← citeshttps://doi.org/10.1007/s11101-025-10190-xopenalex-snapshot
Natural products for the treatment of Chagas disease: a review of plant-derived compounds and related synthetic derivatives as potential trypanocidal drugs
inferred← citeshttps://doi.org/10.1007/s13659-013-0021-zopenalex-snapshot
Three new physalins from Physalis alkekengi var. franchetii
inferred← citeshttps://doi.org/10.1007/s40200-023-01265-7openalex-snapshot
The anti-inflammatory activity of probiotic Dadiah to activate Sirtuin-1 in inhibiting diabetic nephropathy progression
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.14816-4openalex-snapshot
Eight-Membered Rings With One Oxygen Atom
inferred← citeshttps://doi.org/10.1016/b978-0-444-63602-7.00008-4openalex-snapshot
Recent Developments in Natural Product-Based Drug Discovery in Tropical Diseases
inferred← citeshttps://doi.org/10.1016/j.bcp.2013.02.026openalex-snapshot
Chemical informatics uncovers a new role for moexipril as a novel inhibitor of cAMP phosphodiesterase-4 (PDE4)
inferred← citeshttps://doi.org/10.1016/j.chroma.2017.09.070openalex-snapshot
High performance thin-layer chromatography–mass spectrometry enables reliable analysis of physalins in different plant parts of Physalis alkekengi L.
inferred← citeshttps://doi.org/10.1016/j.csbj.2018.11.002openalex-snapshot
YaTCM: Yet another Traditional Chinese Medicine Database for Drug Discovery
inferred← citeshttps://doi.org/10.1016/j.etap.2013.10.013openalex-snapshot
Genotoxicity and antileishmanial activity evaluation of Physalis angulata concentrated ethanolic extract
inferred← citeshttps://doi.org/10.1016/j.fitote.2016.05.010openalex-snapshot
Six new physalins from Physalis alkekengi var. franchetii and their cytotoxicity and antibacterial activity
inferred← citeshttps://doi.org/10.1016/j.foohum.2024.100395openalex-snapshot
Global insights into Physalis research: A bibliometric journey from origin to recent advances
inferred← citeshttps://doi.org/10.1016/j.heliyon.2020.e04897openalex-snapshot
A systematic review on COVID-19 pandemic with special emphasis on curative potentials of Nigeria based medicinal plants
inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e20030openalex-snapshot
Research progress on the chemical components and pharmacological effects of Physalis alkekengi L. var. franchetii (Mast.) Makino
inferred← citeshttps://doi.org/10.1016/j.jarmap.2021.100337openalex-snapshot
Characteristics and methods to release seed dormancy of two ground cherry (Physalis) species
inferred← citeshttps://doi.org/10.1016/j.jep.2013.09.014openalex-snapshot
Physalin F from Physalis minima L. triggers apoptosis-based cytotoxic mechanism in T-47D cells through the activation caspase-3- and c-myc-dependent pathways
inferred← citeshttps://doi.org/10.1016/j.jep.2015.07.033openalex-snapshot
An ethnobotanical study of anti-malarial plants among indigenous people on the upper Negro River in the Brazilian Amazon
inferred← citeshttps://doi.org/10.1016/j.jep.2015.11.048openalex-snapshot
Antimalarial plants used by indigenous people of the Upper Rio Negro in Amazonas, Brazil
inferred← citeshttps://doi.org/10.1016/j.jep.2017.08.022openalex-snapshot
Physalis alkekengi L. var. franchetii (Mast.) Makino: An ethnomedical, phytochemical and pharmacological review
inferred← citeshttps://doi.org/10.1016/j.jep.2023.117595openalex-snapshot
Brazilian plants with antimalarial activity: A review of the period from 2011 to 2022
inferred← citeshttps://doi.org/10.1016/j.jep.2024.117736openalex-snapshot
Genus Physalis L.: A review of resources and cultivation, chemical composition, pharmacological effects and applications
inferred← citeshttps://doi.org/10.1016/j.jinsphys.2012.10.001openalex-snapshot
Physalin B inhibits Trypanosoma cruzi infection in the gut of Rhodnius prolixus by affecting the immune system and microbiota
inferred← citeshttps://doi.org/10.1016/j.micron.2015.12.001openalex-snapshot
Physalis angulata induces death of promastigotes and amastigotes of Leishmania ( Leishmania ) amazonensis via the generation of reactive oxygen species
inferred← citeshttps://doi.org/10.1016/j.molstruc.2019.01.091openalex-snapshot
Design, synthesis, biological evaluation and computational study of novel triazolo [4,3-a]pyrazin analogues
inferred← citeshttps://doi.org/10.1016/j.phymed.2015.07.004openalex-snapshot
In vitro and in vivo antiparasitic activity of Physalis angulata L. concentrated ethanolic extract against Trypanosoma cruzi
inferred← citeshttps://doi.org/10.1016/j.phymed.2020.153294openalex-snapshot
Physalin D attenuates hepatic stellate cell activation and liver fibrosis by blocking TGF-β/Smad and YAP signaling
inferred← citeshttps://doi.org/10.1016/j.phymed.2022.154328openalex-snapshot
Physalis alkekengi L. var. franchetii (Mast.) Makino: A review of the pharmacognosy, chemical constituents, pharmacological effects, quality control, and applications
inferred← citeshttps://doi.org/10.1016/j.sajb.2013.07.025openalex-snapshot
Osmotic priming effects on emergence of Physalis angulata and the influence of abiotic stresses on physalin content
inferred← citeshttps://doi.org/10.1016/j.steroids.2015.08.015openalex-snapshot
Cytotoxic 20,24-epoxywithanolides from Physalis angulata
inferred← citeshttps://doi.org/10.1016/j.tetlet.2019.04.003openalex-snapshot
Physalinol A, a 1,10-seco-physalin with an epidioxy from Physalis alkekengi L. var. franchetii (Mast.) Makino
inferred← citeshttps://doi.org/10.1017/s0031182013001297openalex-snapshot
Physalins B and F,seco-steroids isolated fromPhysalis angulataL., strongly inhibit proliferation, ultrastructure and infectivity ofTrypanosoma cruzi
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.0c00380openalex-snapshot
Cytotoxic Physalins from Aeroponically Grown Physalis acutifolia
inferred← citeshttps://doi.org/10.1021/acschemneuro.9b00166openalex-snapshot
Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Physalin F via Block of CaV2.3 (R-Type) and CaV2.2 (N-Type) Voltage-Gated Calcium Channels
inferred← citeshttps://doi.org/10.1021/np400017kopenalex-snapshot
Physalin A Induces Apoptotic Cell Death and Protective Autophagy in HT1080 Human Fibrosarcoma Cells
inferred← citeshttps://doi.org/10.1021/ol203498aopenalex-snapshot
Physangulidines A, B, and C: Three New Antiproliferative Withanolides from Physalis angulata L.
inferred← citeshttps://doi.org/10.1038/s41573-023-00774-7openalex-snapshot
Artificial intelligence for natural product drug discovery
inferred← citeshttps://doi.org/10.1039/c7ob02193copenalex-snapshot
Harnessing the potential of natural products in drug discovery from a cheminformatics vantage point
inferred← citeshttps://doi.org/10.1039/d1sc04471kopenalex-snapshot
Natural product drug discovery in the artificial intelligence era
inferred← citeshttps://doi.org/10.1055/a-1237-4268openalex-snapshot
In vitro and In Vivo Immunomodulatory Activity of Physalis angulata Concentrated Ethanolic Extract
inferred← citeshttps://doi.org/10.1080/10286020.2020.1825390openalex-snapshot
Bioactive compounds from Physalis angulata and their anti-inflammatory and cytotoxic activities
inferred← citeshttps://doi.org/10.1080/14728222.2021.1901079openalex-snapshot
Macrophage polarization: an effective approach to targeted therapy of inflammatory bowel disease
inferred← citeshttps://doi.org/10.1080/14786419.2019.1705812openalex-snapshot
Physalis angulata concentrated ethanolic extract suppresses nociception and inflammation by modulating cytokines and prostanoids pathways
inferred← citeshttps://doi.org/10.1107/s010827011303117xopenalex-snapshot
Isolation, pharmacological activity and structure determination of physalin B and 5β,6β-epoxyphysalin B isolated from CongolesePhysalis angulataL.
inferred← citeshttps://doi.org/10.1107/s205698902100709xopenalex-snapshot
Withanolides from Physalis angulata L.
inferred← citeshttps://doi.org/10.1177/1934578x1701201016openalex-snapshot
A Novel Cytotoxic Physalin from Physalis angulata
inferred← citeshttps://doi.org/10.1186/1471-2121-15-37openalex-snapshot
Physalis angulata induces in vitro differentiation of murine bone marrow cells into macrophages
inferred← citeshttps://doi.org/10.1186/1475-2875-12-168openalex-snapshot
Malaria in South America: a drug discovery perspective
inferred← citeshttps://doi.org/10.1186/s12906-015-0717-1openalex-snapshot
In vitro biological action of aqueous extract from roots of Physalis angulata against Leishmania (Leishmania) amazonensis
inferred← citeshttps://doi.org/10.1186/s12936-019-3026-1openalex-snapshot
Antiplasmodial natural products: an update
inferred← citeshttps://doi.org/10.1186/s12941-016-0170-0openalex-snapshot
Ethnomedicines and anti-parasitic activities of Pakistani medicinal plants against Plasmodia and Leishmania parasites
inferred← citeshttps://doi.org/10.1186/s13321-016-0130-xopenalex-snapshot
Improving chemical similarity ensemble approach in target prediction
inferred← citeshttps://doi.org/10.1515/psr-2018-0112openalex-snapshot
Drug target prediction using chem- and bioinformatics
inferred← citeshttps://doi.org/10.1515/psr-2018-0115openalex-snapshot
Prediction of modes of action of components of traditional medicinal preparations
inferred← citeshttps://doi.org/10.1556/018.68.2017.3.7openalex-snapshot
Isolation and quantitative analysis of physalin D in the fruit and calyx of Physalis alkekengi L.
inferred← citeshttps://doi.org/10.1590/0074-02760240123openalex-snapshot
Use of Brazilian flora as the main source of new antimalarials: a systematic review
inferred← citeshttps://doi.org/10.1590/1809-4392201701191openalex-snapshot
Ethnobotanical study of antimalarial plants in the middle region of the Negro River, Amazonas, Brazil
inferred← citeshttps://doi.org/10.1590/1983-40632016v4744652openalex-snapshot
Hydroponic cultivation of Physalis angulata L.: growth and production under nitrogen doses1
inferred← citeshttps://doi.org/10.1590/s0074-02762012000700001openalex-snapshot
New approaches in antimalarial drug discovery and development: a review
inferred← citeshttps://doi.org/10.2174/1874467217666230721124057openalex-snapshot
Physalin B Reduces Tau Phosphorylation and Cell Apoptosis in HEK293 Cells by Activating FoxO1
inferred← citeshttps://doi.org/10.21776/ub.jpal.2017.008.02.04openalex-snapshot
Ethnobotanical Study of Toxic Plants in Ngadiwono Village, Tosari District, Pasuruan Regency, East Java
inferred← citeshttps://doi.org/10.22038/ijbms.2017.8583openalex-snapshot
Antimalarial evaluation of selected medicinal plant extracts used in Iranian traditional medicine.
inferred← citeshttps://doi.org/10.22159/ijap.2021.v13s4.43816openalex-snapshot
MEDICINAL HERBS USED IN MANAGEMENT OF MALARIA IN PAMOTAN VILLAGE COMMUNITY, KALIPUCANG DISTRICT, PANGANDARAN REGENCY, WEST JAVA, INDONESIA
inferred← citeshttps://doi.org/10.29356/jmcs.v59i1.16openalex-snapshot
Optimization of Extraction Conditions for Flavonoids of Physalis alkekengi var. franchetii Stems by Response Surface Methodology and Inhibition of Acetylcholinesterase Activity
inferred← citeshttps://doi.org/10.30574/gscbps.2020.12.2.0250openalex-snapshot
Phytochemical screening and antioxidant activity of methanolic extracts of 53 antimalarial plants from Bagira in Eastern DR Congo
inferred← citeshttps://doi.org/10.32712/2446-4775.2021.1086openalex-snapshot
Do quinino aos antimaláricos sintéticos: o conhecimento das plantas medicinais como estratégia potencial na terapia da CoVID-19
inferred← citeshttps://doi.org/10.3329/jbau.v17i3.43206openalex-snapshot
Ethnobotanical uses of plants by Brangkuah Community of Moyo Island, West Nusa Tenggara, Indonesia
inferred← citeshttps://doi.org/10.3389/fphar.2022.864714openalex-snapshot
Therapeutic Applications of Physalins: Powerful Natural Weapons
inferred← citeshttps://doi.org/10.3390/ijms21103646openalex-snapshot
The Role of Ca2+-NFATc1 Signaling and Its Modulation on Osteoclastogenesis
inferred← citeshttps://doi.org/10.3390/molecules27030695openalex-snapshot
Natural Products from Physalis alkekengi L. var. franchetii (Mast.) Makino: A Review on Their Structural Analysis, Quality Control, Pharmacology, and Pharmacokinetics
inferred← citeshttps://doi.org/10.3390/molecules30040916openalex-snapshot
Physalin F, a Potent Inhibitor of Lymphocyte Function, Is a Calcineurin Inhibitor and Has Synergistic Effect with Dexamethasone
inferred← citeshttps://doi.org/10.3390/ph19050715openalex-snapshot
ComTarget: Small-Molecule Target Prediction with Combinatorial Modeling
inferred← citeshttps://doi.org/10.3390/plants12091813openalex-snapshot
Potential Plant-Based New Antiplasmodial Agent Used in Papua Island, Indonesia
inferred← citeshttps://doi.org/10.4103/pr.pr_97_18openalex-snapshot
Anatomical and phytochemical characterization of Physalis angulata L.: A plant with therapeutic potential
inferred← citeshttps://doi.org/10.51891/rease.v9i9.10479openalex-snapshot
POTENCIAL ANTIMALÁRICO DE PLANTAS MEDICINAIS: UMA REVISÃO INTEGRATIVA
inferred← citeshttps://doi.org/10.5483/bmbrep.2020.53.3.147openalex-snapshot
Physalin D inhibits RANKL-induced osteoclastogenesis and bone loss via regulating calcium signaling
inferred← citeshttps://doi.org/10.5772/intechopen.82461openalex-snapshot
Medicinal Plants of the Peruvian Amazon: Bioactive Phytochemicals, Mechanisms of Action, and Biosynthetic Pathways
inferred← citeshttps://doi.org/10.70675/ccf4b7fez64aez4e4bzaebfzd812e9e9aa54openalex-snapshot
Phytochemical study and biological evaluation of five plants belonging to the family Solanaceae
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