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Flavonolignans from Aspergillus iizukae, a Fungal Endophyte of Milk Thistle (Silybum marianum)

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/mc.20670openalex-snapshot
Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF‐κB, and androgen receptor signaling
inferredcites →https://doi.org/10.1002/ptr.3207openalex-snapshot
Milk thistle in liver diseases: past, present, future
inferredcites →https://doi.org/10.1007/978-1-4612-3168-4openalex-snapshot
Microbial Ecology of Leaves
inferredcites →https://doi.org/10.1007/978-1-4612-3168-4_9openalex-snapshot
Fungal Endophytes of Tree Leaves
inferredcites →https://doi.org/10.1007/s10555-010-9237-0openalex-snapshot
Antimetastatic efficacy of silibinin: molecular mechanisms and therapeutic potential against cancer
inferredcites →https://doi.org/10.1007/s11274-011-0876-2openalex-snapshot
An endophytic fungus from Azadirachta indica A. Juss. that produces azadirachtin
inferredcites →https://doi.org/10.1016/b978-012509551-8/50015-5openalex-snapshot
ENDOPHYTIC FUNGI
inferredcites →https://doi.org/10.1016/j.bmc.2012.11.035openalex-snapshot
Enhanced bioactivity of silybin B methylation products
inferredcites →https://doi.org/10.1016/j.bmc.2013.04.017openalex-snapshot
Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle
inferredcites →https://doi.org/10.1016/j.canlet.2008.03.053openalex-snapshot
Multitargeted therapy of cancer by silymarin
inferredcites →https://doi.org/10.1016/j.chembiol.2012.06.004openalex-snapshot
Chemical Ecology of Endophytic Fungi: Origins of Secondary Metabolites
inferredcites →https://doi.org/10.1016/j.fbr.2007.05.003openalex-snapshot
Understanding the diversity of foliar endophytic fungi: progress, challenges, and frontiers
inferredcites →https://doi.org/10.1016/j.jbiotec.2005.10.015openalex-snapshot
The endophytic fungus Trametes hirsuta as a novel alternative source of podophyllotoxin and related aryl tetralin lignans
inferredcites →https://doi.org/10.1016/j.phymed.2012.11.015openalex-snapshot
Endophytic fungi from Miquelia dentata Bedd., produce the anti-cancer alkaloid, camptothecine
inferredcites →https://doi.org/10.1016/j.phytochem.2009.09.030openalex-snapshot
Endophytic fungal strains of Fusarium solani, from Apodytes dimidiata E. Mey. ex Arn (Icacinaceae) produce camptothecin, 10-hydroxycamptothecin and 9-methoxycamptothecin
inferredcites →https://doi.org/10.1016/j.phytochem.2012.07.021openalex-snapshot
Untapped mutualistic paradigms linking host plant and endophytic fungal production of similar bioactive secondary metabolites
inferredcites →https://doi.org/10.1016/s0953-7562(09)80215-3openalex-snapshot
Endophytes from herbaceous plants and shrubs: effectiveness of surface sterilization methods
inferredcites →https://doi.org/10.1021/jo302720hopenalex-snapshot
HiFSA Fingerprinting Applied to Isomers with Near-Identical NMR Spectra: The Silybin/Isosilybin Case
inferredcites →https://doi.org/10.1021/jo4011377openalex-snapshot
Mechanistic Study of the Biomimetic Synthesis of Flavonolignan Diastereoisomers in Milk Thistle
inferredcites →https://doi.org/10.1021/np0502802openalex-snapshot
An Endophytic Fungus from Nothapodytes foetida that Produces Camptothecin
inferredcites →https://doi.org/10.1021/np060174fopenalex-snapshot
Endophyte Fungal Isolates fromPodophyllumpeltatumProduce Podophyllotoxin
inferredcites →https://doi.org/10.1021/np070669kopenalex-snapshot
An Endophytic Fungus from Hypericum perforatum that Produces Hypericin
inferredcites →https://doi.org/10.1021/np1008398openalex-snapshot
Effect of Artificial Reconstitution of the Interaction between the Plant Camptotheca acuminata and the Fungal Endophyte Fusarium solani on Camptothecin Biosynthesis
inferredcites →https://doi.org/10.1021/np3005369openalex-snapshot
Absolute Configuration of Isosilybin A by X-ray Crystallography of the Heavy Atom Analogue 7-(4-Bromobenzoyl)isosilybin A
inferredcites →https://doi.org/10.1021/np300749wopenalex-snapshot
Benzoquinones and Terphenyl Compounds As Phosphodiesterase-4B Inhibitors from a Fungus of the Order Chaetothyriales (MSX 47445)
inferredcites →https://doi.org/10.1021/np4004307openalex-snapshot
High-Resolution MS, MS/MS, and UV Database of Fungal Secondary Metabolites as a Dereplication Protocol for Bioactive Natural Products
inferredcites →https://doi.org/10.1021/np800455bopenalex-snapshot
An Endophytic Fungus from Camptotheca acuminata That Produces Camptothecin and Analogues
inferredcites →https://doi.org/10.1021/np9002977openalex-snapshot
Light-Independent Metabolomics of Endophytic Thielavia subthermophila Provides Insight into Microbial Hypericin Biosynthesis
inferredcites →https://doi.org/10.1038/ja.2010.77openalex-snapshot
Dereplication of macrocyclic trichothecenes from extracts of filamentous fungi through UV and NMR profiles
inferredcites →https://doi.org/10.1055/s-2007-990239openalex-snapshot
Gram-Scale Purification of Flavonolignan Diastereoisomers from Silybum marianum (Milk Thistle) Extract in Support of Preclinical in vivo Studies for Prostate Cancer Chemoprevention
inferredcites →https://doi.org/10.1073/pnas.0914009107openalex-snapshot
Identification of hepatoprotective flavonolignans from silymarin
inferredcites →https://doi.org/10.1073/pnas.1117018109openalex-snapshot
Nuclear ribosomal internal transcribed spacer (ITS) region as a universal DNA barcode marker for Fungi
inferredcites →https://doi.org/10.1080/10635150600899780openalex-snapshot
Statistical Methods in Molecular Evolution
inferredcites →https://doi.org/10.1080/14786410902750944openalex-snapshot
Comparative studies and identification of camptothecin produced by an endophyte at shake flask and bioreactor
inferredcites →https://doi.org/10.1080/15572536.2008.11832477openalex-snapshot
Phylogenetic analysis of Aspergillus species using DNA sequences from four loci
inferredcites →https://doi.org/10.1093/bioinformatics/btl446openalex-snapshot
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models
inferredcites →https://doi.org/10.1093/bioinformatics/bts309openalex-snapshot
RAxML-Light: a tool for computing terabyte phylogenies
inferredcites →https://doi.org/10.1093/carcin/bgm069openalex-snapshot
Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells
inferredcites →https://doi.org/10.1093/molbev/msp259openalex-snapshot
SeaView Version 4: A Multiplatform Graphical User Interface for Sequence Alignment and Phylogenetic Tree Building
inferredcites →https://doi.org/10.1093/nar/gkh340openalex-snapshot
MUSCLE: multiple sequence alignment with high accuracy and high throughput
inferredcites →https://doi.org/10.1093/oxfordjournals.molbev.a040548openalex-snapshot
Phylogeny of some Fusarium species, as determined by large-subunit rRNA sequence comparison.
inferredcites →https://doi.org/10.1109/gce.2010.5676129openalex-snapshot
Creating the CIPRES Science Gateway for inference of large phylogenetic trees
inferredcites →https://doi.org/10.1111/j.1365-2672.2009.04285.xopenalex-snapshot
Aspergillus fumigatusFresenius, an endophytic fungus fromJuniperus communisL. Horstmann as a novel source of the anticancer pro-drug deoxypodophyllotoxin
inferredcites →https://doi.org/10.1126/science.8097061openalex-snapshot
Taxol and Taxane Production by Taxomyces andreanae , an Endophytic Fungus of Pacific Yew
inferredcites →https://doi.org/10.1134/s0003683808020130openalex-snapshot
An endophytic Neurospora sp. from Nothapodytes foetida producing camptothecin
inferredcites →https://doi.org/10.1158/0008-5472.can-04-4662openalex-snapshot
Milk Thistle and Prostate Cancer: Differential Effects of Pure Flavonolignans from Silybum marianum on Antiproliferative End Points in Human Prostate Carcinoma Cells
inferredcites →https://doi.org/10.1177/1534735407301825openalex-snapshot
Milk Thistle Nomenclature: Why It Matters in Cancer Research and Pharmacokinetic Studies
inferredcites →https://doi.org/10.1177/1534735407302349openalex-snapshot
Toward the Definition of the Mechanism of Action of Silymarin: Activities Related to Cellular Protection From Toxic Damage Induced by Chemotherapy
inferredcites →https://doi.org/10.1371/journal.pone.0016464openalex-snapshot
Differential In Vitro Effects of Intravenous versus Oral Formulations of Silibinin on the HCV Life Cycle and Inflammation
inferredcites →https://doi.org/10.1371/journal.pone.0034630openalex-snapshot
Angiopreventive Efficacy of Pure Flavonolignans from Milk Thistle Extract against Prostate Cancer: Targeting VEGF-VEGFR Signaling
inferredcites →https://doi.org/10.2174/092986707779941159openalex-snapshot
Silybin and Silymarin - New and Emerging Applications in Medicine
inferredcites →https://doi.org/10.2307/1943154openalex-snapshot
Fungal Endophytes in Stems and Leaves: From Latent Pathogen to Mutualistic Symbiont
inferredcites →https://doi.org/10.3851/imp2402openalex-snapshot
Silymarin for HCV infection

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Recent advances in inducing endophytic fungal specialized metabolites using small molecule elicitors including epigenetic modifiers
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Biosynthetically Distinct Cytotoxic Polyketides from Setophoma terrestris
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Aspergillus from Different Habitats and Their Industrial Applications
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Fungal Endophytes as Potential Anticancer Candidate over Synthetic Drugs: Latest Development and Future Prospects
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Unraveling the Chemical Interactions of Fungal Endophytes for Exploitation as Microbial Factories
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Diversity, Ecology, and Significance of Fungal Endophytes
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Diversity, Ecology, and Significance of Fungal Endophytes
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Diversity, Ecology, and Significance of Fungal Endophytes
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Epigenetic Reprogramming by Endophytes: Unlocking Silent Biosynthetic Gene Clusters for Next-Generation Phytopharmaceuticals
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Bioactive Metabolites from Fungi with Anti-Inflammatory and Antithrombotic Properties: Current Status and Future Perspectives for Drug Development
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Exploiting endophytic microbes as micro-factories for plant secondary metabolite production
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Enhanced podophyllotoxin production of endophyte Fusarium proliferatum TQN5T by host extract and phenylalanine
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Optimizing production and evaluating biosynthesis in situ of a herbicidal compound, mevalocidin, from Coniolariella sp.
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Epigenetic modifiers as inducer of bioactive secondary metabolites in fungi
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Strain identification and metabolites isolation of Aspergillus capensis CanS-34A from Brassica napus
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Endophyte-produced antimicrobials: a review of potential lead compounds with a focus on quorum-sensing disruptors
inferred← citeshttps://doi.org/10.1007/s11274-015-1916-0openalex-snapshot
Restoration of camptothecine production in attenuated endophytic fungus on re-inoculation into host plant and treatment with DNA methyltransferase inhibitor
inferred← citeshttps://doi.org/10.1007/s11356-017-9770-2openalex-snapshot
Isolation of limonoid compound (Hamisonine) from endophytic fungi Penicillium oxalicum LA-1 (KX622790) of Limonia acidissima L. for its larvicidal efficacy against LF vector, Culex quinquefasciatus (Diptera: Culicidae)
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Phytonutrients as a Defensive Barrier Against G Ectodomain Fusion in Chandipura Virus Infection
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The Potential of Fungal Endophytes in Plants: Sources of Bioactive Compounds
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Uncovering Bioactive Natural Products Via Biochemometric Methodologies
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Antitumor and Immunomodulatory Compounds from Fungi
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Silybins: Antiviral liver analeptics
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Endophyte-aided drug discovery: design, and development from psychotic plants
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Endophytic fungi in anticancer drug development: Targeting tumor microenvironment
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Antioxidant and antiinflammatory endophytic fungal compounds for chronic diseases
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Endophytic fungi as sources of cardiovascular drug leads
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Commercialization of endophytic fungus–derived therapeutics: Opportunities and challenges
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Epilogue: microbes, technology, and the future of drug discovery
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Metabolite profiling of endophytic microorganisms for drug discovery
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Anti-HCV protease potential of endophytic fungi and cytotoxic activity
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Iizukines C−E from a saline soil fungus Aspergillus iizukae
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Unlocking the possibilities of therapeutic potential of silymarin and silibinin against neurodegenerative Diseases-A mechanistic overview
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Chemotaxonomic and biosynthetic relationships between flavonolignans produced by Silybum marianum populations
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The food plant Silybum marianum (L.) Gaertn.: Phytochemistry, Ethnopharmacology and clinical evidence
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Anticancer flavonoids producing endophytic fungi: A review
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Recent advances in the analysis of flavonolignans of Silybum marianum
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Plant-endophyte associations: Rich yet under-explored sources of novel bioactive molecules and applications
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Talarolutins A–D: Meroterpenoids from an endophytic fungal isolate of Talaromyces minioluteus
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Comparison of the chemistry and diversity of endophytes isolated from wild-harvested and greenhouse-cultivated yerba mansa (Anemopsis californica)
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Antimicrobial fungal endophytes from the botanical medicine goldenseal ( Hydrastis canadensis )
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Overview of bioactive metabolite(s) produced by endophytes and future perspectives on epigenetic modification/regulation of cryptic biosynthetic pathways
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Exploring bioactive metabolites produced by endophytes associated with the genus Curcuma L.: A pharmaceutical prospect
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Epigenetic-based developments in the field of plant endophytic fungi
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Antiproliferation and combinatorial antibacterial effects of extracts and endophytes from a South African biotype of Chromolaena odorata against β-lactamase producing bacteria
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Endophytic fungi: A potential source of bioactive compounds
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RETRACTED: Cladophialophora bantiana metabolites are efficient in the larvicidal and ovicidal control of Aedes aegypti, and Culex quinquefasciatus and have low toxicity in zebrafish embryo
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Re-examination of species limits in Aspergillus section Flavipedes using advanced species delimitation methods and description of four new species
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Are Microbial Endophytes the ‘Actual’ Producers of Bioactive Antitumor Agents?
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Ethnobotany and the Role of Plant Natural Products in Antibiotic Drug Discovery
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Dereplicating and Spatial Mapping of Secondary Metabolites from Fungal Cultures in Situ
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Natural Products as Sources of New Drugs from 1981 to 2014
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Fungal Identification Using Molecular Tools: A Primer for the Natural Products Research Community
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Mass Spectrometry-Based Technology and Workflows for Studying the Chemistry of Fungal Endophyte Derived Bioactive Compounds
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Sustainable production of camptothecin from an Alternaria sp. isolated from Nothapodytes nimmoniana
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Screening and selection of camptothecin producing endophytes from Nothapodytes nimmoniana
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Chemistry of silybin
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Mass spectrometry imaging of secondary metabolites directly on fungal cultures
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Chemical signaling involved in plant–microbe interactions
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Engineering enzymatic cascades for the efficient biotransformation of eugenol and taxifolin to silybin and isosilybin
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Selection and characterization of botanical natural products for research studies: a NaPDI center recommended approach
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Plant Endophytes and Epiphytes: Burgeoning Sources of Known and “Unknown” Cytotoxic and Antibiotic Agents?
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Drug Leads from Endophytic Fungi: Lessons Learned via Scaled Production
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Re-Identification of Aspergillus Subgenus Circumdati Strains in Korea Led to the Discovery of Three Unrecorded Species
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The impact of decreasing biodiversity on novel drug discovery: is there a serious cause for concern?
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Phylogenetic and chemical diversity of fungal endophytes isolated from Silybum marianum (L) Gaertn. (milk thistle)
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Plant associated fungal endophytes as a source of natural bioactive compounds
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Natural flavonolignans as potential therapeutic agents against common diseases
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Sustainable Production of Camptothecin from an Alternaria sp. isolated from Nothapodytes nimmoniana
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Solamargine production by a fungal endophyte of Solanum nigrum
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Endophytic fungi residing in medicinal plants have the ability to produce the same or similar pharmacologically active secondary metabolites as their hosts
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Bioactive Secondary Metabolites from Endophytic Fungi
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Role of Flavonoids in Neurodegenerative Diseases: Limitations and Future Perspectives
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A Review on Medicinal Plants Having Anticancer Properties of Northeast India and Associated Endophytic Microbes and their Future in Medicinal Science
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The Influence of Microbial Endophytes/Epiphytes on Medicinal Plant Components
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Computational Literature-based Discovery for Natural Products Research: Current State and Future Prospects
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Predominately Uncultured Microbes as Sources of Bioactive Agents
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Profiling of the Transcriptomic Responses of Clonostachys rosea Upon Treatment With Fusarium graminearum Secretome
inferred← citeshttps://doi.org/10.3389/fphar.2018.00422openalex-snapshot
Anti-Parkinson Potential of Silymarin: Mechanistic Insight and Therapeutic Standing
inferred← citeshttps://doi.org/10.3390/agriculture10070286openalex-snapshot
Linking Endophytic Fungi to Medicinal Plants Therapeutic Activity. A Case Study on Asteraceae
inferred← citeshttps://doi.org/10.3390/agriculture5040918openalex-snapshot
Plant Bioactive Metabolites and Drugs Produced by Endophytic Fungi of Spermatophyta
inferred← citeshttps://doi.org/10.3390/ijms241210096openalex-snapshot
Plants as the Extended Phenotype of Endophytes—The Actual Source of Bioactive Compounds
inferred← citeshttps://doi.org/10.3390/ijms27031365openalex-snapshot
Mining the Hidden Pharmacopeia: Fungal Endophytes, Natural Products, and the Rise of AI-Driven Drug Discovery
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Silybum marianum-Derived Compounds in Prostate Cancer: Mechanisms of Action and Translational Potential
inferred← citeshttps://doi.org/10.3390/jmse14121106openalex-snapshot
First Insights into the Biochemical and Metabolomic Characterization of Marine Fungi Isolated from Salt Marshes of an Argentine Estuary
inferred← citeshttps://doi.org/10.3390/md16110449openalex-snapshot
Potential Antiviral Xanthones from a Coastal Saline Soil Fungus Aspergillus iizukae
inferred← citeshttps://doi.org/10.3390/metabo13030440openalex-snapshot
Detecting and Profiling of Milk Thistle Metabolites in Food Supplements: A Safety-Oriented Approach by Advanced Analytics
inferred← citeshttps://doi.org/10.3390/microorganisms10020360openalex-snapshot
Endophytic Fungi: Key Insights, Emerging Prospects, and Challenges in Natural Product Drug Discovery
inferred← citeshttps://doi.org/10.3390/microorganisms9010197openalex-snapshot
Fungal Endophytes as Efficient Sources of Plant-Derived Bioactive Compounds and Their Prospective Applications in Natural Product Drug Discovery: Insights, Avenues, and Challenges
inferred← citeshttps://doi.org/10.3390/su15043126openalex-snapshot
Molecular Identification of Endophytic Bacteria from Silybum marianum and Their Effect on Brassica napus Growth under Heavy Metal Stress
inferred← citeshttps://doi.org/10.3390/su15075902openalex-snapshot
New Fungal Strains from Peat Soil in Malaysia: Morphological and Molecular Characteristics
inferred← citeshttps://doi.org/10.3852/14-059openalex-snapshot
Revision of Aspergillus section Flavipedes : seven new species and proposal of section Jani sect. nov.
inferred← citeshttps://doi.org/10.5772/intechopen.99717openalex-snapshot
The Diversity of Endophytic Aspergillus
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