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Marine Natural Product Libraries for High-Throughput Screening and Rapid Drug Discovery

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.cbpa.2007.08.012openalex-snapshot
Natural products as a screening resource
inferredcites →https://doi.org/10.1016/j.tim.2007.04.001openalex-snapshot
New aspects of natural products in drug discovery
inferredcites →https://doi.org/10.1016/s0040-4039(00)89041-3openalex-snapshot
Plakinidines: Cytotoxic alkaloid pigments from the fijian sponge plakortis sp.
inferredcites →https://doi.org/10.1021/ac025516aopenalex-snapshot
High-Throughput Analysis of Natural Product Compound Libraries by Parallel LC−MS Evaporative Light Scattering Detection
inferredcites →https://doi.org/10.1021/ac025534sopenalex-snapshot
High-Throughput Method for the Production and Analysis of Large Natural Product Libraries for Drug Discovery
inferredcites →https://doi.org/10.1021/ac069383vopenalex-snapshot
Monolithic Materials: Promises, Challenges, Achievements
inferredcites →https://doi.org/10.1021/ja00157a001openalex-snapshot
Novel marine sponge alkaloids. 1. Plakinidine A and B, anthelmintic active alkaloids from a Plakortis sponge
inferredcites →https://doi.org/10.1021/jm060029zopenalex-snapshot
Synergy and Antagonism of Promiscuous Inhibition in Multiple-Compound Mixtures
inferredcites →https://doi.org/10.1021/jo981022vopenalex-snapshot
Crellastatin A: A Cytotoxic Bis-Steroid Sulfate from the Vanuatu Marine Sponge Crella sp.
inferredcites →https://doi.org/10.1021/np040031yopenalex-snapshot
Marine Natural Products and Related Compounds in Clinical and Advanced Preclinical Trials
inferredcites →https://doi.org/10.1021/np060555topenalex-snapshot
Accelerating the Discovery of Biologically Active Small Molecules Using a High-Throughput Yeast Halo Assay
inferredcites →https://doi.org/10.1021/np060585wopenalex-snapshot
Pyrroloacridine Alkaloids from Plakortis quasiamphiaster: Structures and Bioactivity
inferredcites →https://doi.org/10.1021/np068054vopenalex-snapshot
Natural Products as Sources of New Drugs over the Last 25 Years
inferredcites →https://doi.org/10.1021/np070002yopenalex-snapshot
ChemGPS-NP: Tuned for Navigation in Biologically Relevant Chemical Space
inferredcites →https://doi.org/10.1038/nrd1657openalex-snapshot
The evolving role of natural products in drug discovery
inferredcites →https://doi.org/10.1039/a901323gopenalex-snapshot
Structure and total synthesis of benzylthiocrellidone, a novel dimedone-based vinyl sulfide from the sponge Crella spinulata
inferredcites →https://doi.org/10.1101/gad.14.11.1400openalex-snapshot
Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation
inferredcites →https://doi.org/10.1128/mcb.22.2.669-679.2002openalex-snapshot
Brca2 (XRCC11) Deficiency Results in Radioresistant DNA Synthesis and a Higher Frequency of Spontaneous Deletions
inferredcites →https://doi.org/10.2174/138945006776054960openalex-snapshot
Natural Products from Marine Invertebrates and Microbes as Modulators of Antitumor Targets

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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New sciaphilic plakinids (Porifera, Homoscleromorpha) from the Central-Western Pacific
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New Strategies for Natural Products Lead Generation
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Natural Product‐Based Libraries
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Marine Bioprospecting
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Natural Product Drug Discovery and Analysis Using Mass Spectrometry and Affinity‐Based Technologies
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Trends in Development of Marine‐based Anti‐inflammatory Pharmaceuticals
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Miniaturized Cultivation of Microbiota for Antimalarial Drug Discovery
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Medicinal Chemistry and Ligand Profiling for Evaluation of Promising Marine Bioactive Molecules
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High-Throughput Fractionation of Natural Products for Drug Discovery
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Natural Products Dereplication: Databases and Analytical Methods
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Plant Compounds Acting on the Cytoskeleton
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Microbial Fraction Library: A Screening Source for Drug Discovery
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Bioprospecting: Boon or Curse
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Computational Methods in Natural Products-Based Drug Discovery
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Trichoderone, a novel cytotoxic cyclopentenone and cholesta-7, 22-diene-3β, 5α, 6β-triol, with new activities from the marine-derived fungus Trichoderma sp.
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Current approaches to exploit actinomycetes as a source of novel natural products
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Natural and non-toxic products from Fabaceae Brazilian plants as a replacement for traditional antifouling biocides: an inhibition potential against initial biofouling
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Antimicrobial activity and bioactive profiling of heterocytous cyanobacterial strains using MS/MS-based molecular networking
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Scaffold Flatness: Reversing the Trend
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Fraction Libraries and Genetics as Tools for Natural Product Research: Focus on Decalin-Containing Compounds
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Marine Natural Products in Fighting Microbial Infections
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Secondary metabolites from marine fungi: current status and application
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Online Combination of Bioassays with Chemical and Structural Characterization for Detection of Bioactive Compounds
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Advances in the discovery and development of anthelmintics by harnessing natural product scaffolds
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A renaissance in marine pharmacology: From preclinical curiosity to clinical reality
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Bio-mining the microbial treasures of the ocean: New natural products
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Metabolite induction via microorganism co-culture: A potential way to enhance chemical diversity for drug discovery
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Molecular biodiversity and recent analytical developments: A marriage of convenience
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Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives
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Isolation of the β-galactosphingolipid coniferoside using a tumor cell proteome reverse affinity protocol
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Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase
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Marine natural products as inhibitors of cystathionine beta-synthase activity
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Construction of a microbial natural product library for chemical biology studies
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Chromatographic profiling and multivariate analysis for screening and quantifying the contributions from individual components to the bioactive signature in natural products
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A NMR-based drug screening strategy for discovering active substances from herbal medicines: Using Radix Polygoni Multiflori as example
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Hybrid MS/NMR methods on the prioritization of natural products: Applications in drug discovery
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Plant based natural products as potential ecofriendly and safer biopesticides: A comprehensive overview of their advantages over conventional pesticides, limitations and regulatory aspects
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Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns
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Metal-free one-pot synthesis of pyrroloacridine derivatives mediated by achiral nicotinic acid
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Analytical techniques for discovery of bioactive compounds from marine fungi
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Natural products and the search for novel vaccine adjuvants
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Basics and Principles for Building Natural Product–based Libraries for HTS
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Microbial Strain Prioritization Using Metabolomics Tools for the Discovery of Natural Products
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Deguelins, Natural Product Modulators of NF1-Defective Astrocytoma Cell Growth Identified by High-Throughput Screening of Partially Purified Natural Product Extracts
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Total Synthesis of (±)-Marinopyrrole A and Its Library as Potential Antibiotic and Anticancer Agents
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CYANOS: A Data Management System for Natural Product Drug Discovery Efforts Using Cultured Microorganisms
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Development of a Natural-Product-Derived Chemical Toolbox for Modulation of Protein Function
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Fusarisetin A, an Acinar Morphogenesis Inhibitor from a Soil Fungus, Fusarium sp. FN080326
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A Simple Microscale Method for Determining the Relative Stereochemistry of Statine Units
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First Total Synthesis of (+)-Varitriol
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Explorative Solid-Phase Extraction (E-SPE) for Accelerated Microbial Natural Product Discovery, Dereplication, and Purification
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Modern Natural Products Drug Discovery and Its Relevance to Biodiversity Conservation
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Natural Product Libraries to Accelerate the High-Throughput Discovery of Therapeutic Leads
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Drug-like Properties: Guiding Principles for the Design of Natural Product Libraries
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Comparative Study of Chromatographic Medium-Associated Mass and Potential Antitumor Activity Loss with Bioactive Extracts
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UPLC-MS-ELSD-PDA as a Powerful Dereplication Tool to Facilitate Compound Identification from Small-Molecule Natural Product Libraries
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Carteriosulfonic Acids A−C, GSK-3β Inhibitors from a Carteriospongia sp.
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Assessing Pressurized Liquid Extraction for the High-Throughput Extraction of Marine-Sponge-Derived Natural Products
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Automated High-Throughput System to Fractionate Plant Natural Products for Drug Discovery
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Verticilactam, a New Macrolactam Isolated from a Microbial Metabolite Fraction Library
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Total Synthesis of Bengazole A
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Bioprospecting microbial natural product libraries from the marine environment for drug discovery
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Spirotoamides A and B, novel 6,6-spiroacetal polyketides isolated from a microbial metabolite fraction library
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The re-emergence of natural products for drug discovery in the genomics era
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Synthetic biology to access and expand nature's chemical diversity
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Advances in Instrumentation, Automation, Dereplication and Prefractionation
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Investigations of the marine flora and fauna of the Fiji Islands
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Matching the power of high throughput screening to the chemical diversity of natural products
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A diversity oriented synthesis of natural product inspired molecular libraries
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Creating and screening natural product libraries
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The isolation of water-soluble natural products – challenges, strategies and perspectives
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Exploring Marine Resources for Bioactive Compounds
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Combined LC/UV/MS and NMR Strategies for the Dereplication of Marine Natural Products
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High-throughput functional annotation of natural products by integrated activity profiling
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Detection and characterization of new mangromicin analogs by tandem mass spectrometry
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Probing the Phycosphere: Techniques to Study Bacteria-Phytoplankton Interactions
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Synergy between machine learning and natural products cheminformatics: Application to the lead discovery of anthraquinone derivatives
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Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
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Natural Products as Potential Antiviral Drugs: The Specific Case of Marine Biotoxins
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Prediction of Radix Astragali Immunomodulatory Effect of CD80 Expression from Chromatograms by Quantitative Pattern-Activity Relationship
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An agonist sensitive, quick and simple cell-based signaling assay for determination of ligands mimicking prostaglandin E2 or E1 activity through subtype EP1 receptor: Suitable for high throughput screening
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Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
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Marine-derived microbes and molecules for drug discovery
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Screening and identification of novel biologically active natural compounds
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Violaceols Function as Actin Inhibitors Inducing Cell Shape Elongation in Fibroblast Cells
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Low-Volume Toolbox for the Discovery of Immunosuppressive Fungal Secondary Metabolites
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Current strategies for drug discovery through natural products
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Bioprospecting for bioactives from seaweeds: potential, obstacles and alternatives
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Drug discovery and natural products: end of era or an endless frontier?
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Antibacterial and insecticidal activity of volatile compounds of three algae species of Oman Sea
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What Makes Species Productive of Anti-Cancer Drugs? Clues from Drugs’ Species Origin, Druglikeness, Target and Pathway
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Pharmaceutical Crops: An Overview~!2010-04-22~!2010-07-05~!2010-08-12~!
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High Throughput Screening Techniques in Anticancer Drug Discovery and Development from Botanicals
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In silico analysis of correlation between physicochemical properties of ligands and binding affinity to protein targets
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Identification of Anti-tubercular Compounds in Marine Organisms from Aotearoa
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Toward the Synthesis of (–)-TAN-2483B Lactam Analogues
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Toward the Synthesis of (–)-TAN-2483B Lactam Analogues
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Potential Inhibitors of Fascin From A Database of Marine Natural Products: A Virtual Screening and Molecular Dynamics Study
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From structural determination of natural products in complex mixtures to single cell resolution: Perspectives on advances and challenges for mass spectrometry
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Marine-derived surfactin derivatives suppress collagen production and interfere with the HSP47-collagen interaction in preclinical models
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Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery
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Alkaloids from the Sponge Stylissa carteri Present Prospective Scaffolds for the Inhibition of Human Immunodeficiency Virus 1 (HIV-1)
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Bioactive Potential of Marine Macroalgae from the Central Red Sea (Saudi Arabia) Assessed by High-Throughput Imaging-Based Phenotypic Profiling
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Topsentinol L Trisulfate, a Marine Natural Product That Targets Basal-like and Claudin-Low Breast Cancers
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Terpenyl-Purines from the Sea
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Development of Novel Drugs from Marine Surface Associated Microorganisms
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Evaluation of Pyridoacridine Alkaloids in a Zebrafish Phenotypic Assay
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High-Throughput Screening of Natural Product and Synthetic Molecule Libraries for Antibacterial Drug Discovery
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Fractionated Marine Invertebrate Extract Libraries for Drug Discovery
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Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease
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Potential Vaccines and Post-Exposure Treatments for Filovirus Infections
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Guiding Principles for Natural Product Drug Discovery
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Assessment of High-Throughput Screening (HTS) Methods for High-Consequence Pathogens
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Natural Products: Back to the Future in Drug Discovery
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Construção de bibliotecas de compostos microbianos utilizando metodologias modernas para produção e análises de metabólitos secundários
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Role of the Mass Spectrometry in the Screening for New Microbial Natural Products
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Bioprospecting: Creating a Value for Biodiversity
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Additional file 10 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100862openalex-snapshot
Additional file 11 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100865openalex-snapshot
Additional file 12 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100868openalex-snapshot
Additional file 13 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100871openalex-snapshot
Additional file 14 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100874openalex-snapshot
Additional file 15 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100877openalex-snapshot
Additional file 16 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100880openalex-snapshot
Additional file 1 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100883openalex-snapshot
Additional file 2 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100886openalex-snapshot
Additional file 3 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100889openalex-snapshot
Additional file 4 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100892openalex-snapshot
Additional file 5 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100895openalex-snapshot
Additional file 6 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100898openalex-snapshot
Additional file 7 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100901openalex-snapshot
Additional file 8 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.6084/m9.figshare.13100904openalex-snapshot
Additional file 9 of Development of a novel and rapid phenotype-based screening method to assess rice seedling growth
inferred← citeshttps://doi.org/10.70389/pjs.100279openalex-snapshot
Artificial Intelligence and Computational Modeling in Natural Product Drug Discovery
inferred← citeshttps://doi.org/10.70675/efb2d03ezcc25z4daazb84bz181aed5306d6openalex-snapshot
Total Synthesis of Microsclerodermin D
inferred← citeshttps://doi.org/10.7554/elife.24214openalex-snapshot
Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae
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