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Structure−Activity Relationship and Classification of Flavonoids as Inhibitors of Xanthine Oxidase and Superoxide Scavengers

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/0003-2697(84)90467-6openalex-snapshot
Reevaluation of assay methods and establishment of kit for superoxide dismutase activity
inferredcites →https://doi.org/10.1016/0006-2952(91)90311-ropenalex-snapshot
Methylene blue as an inhibitor of superoxide generation by xanthine oxidase
inferredcites →https://doi.org/10.1016/0076-6879(90)86128-iopenalex-snapshot
[36] Flavonoids as antioxidants: Determination of radical-scavenging efficiencies
inferredcites →https://doi.org/10.1016/0076-6879(90)86161-nopenalex-snapshot
[69] Measurement of xanthine oxidase in biological tissues
inferredcites →https://doi.org/10.1016/0891-5849(91)90181-2openalex-snapshot
In vitro scavenger activity of some flavonoids and melanins against O2
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inferredcites →https://doi.org/10.1016/s0021-9258(18)62884-4openalex-snapshot
Quantitative Aspects of the Production of Superoxide Anion Radical by Milk Xanthine Oxidase
inferredcites →https://doi.org/10.1055/s-2006-960357openalex-snapshot
Partial Purification and Substrate Specifity of a β-Glucosidase fromChamomilla recutita

What points at this work

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Generation of cellular reactive oxygen and nitrogen species by exposure to ultraviolet radiation
inferred← citeshttps://doi.org/10.1007/s13105-011-0117-zopenalex-snapshot
Effects of Greek legume plant extracts on xanthine oxidase, catalase and superoxide dismutase activities
inferred← citeshttps://doi.org/10.1007/s13577-025-01334-4openalex-snapshot
Antitumoral effect of Nitraria retusa bioactive compounds on two glioblastoma cell lines
inferred← citeshttps://doi.org/10.1007/s13738-018-1429-5openalex-snapshot
Chrysin/β-cyclodextrin supramolecular system: a quantum mechanical investigation
inferred← citeshttps://doi.org/10.1007/s40009-020-00903-5openalex-snapshot
Antioxidant Properties and Phenolic Contents of Traditional Rice-Based Alcoholic Beverages of Assam, India
inferred← citeshttps://doi.org/10.1007/s42242-020-00085-5openalex-snapshot
3D bioprinted breast tumor model for structure–activity relationship study
inferred← citeshttps://doi.org/10.1007/s42995-020-00066-8openalex-snapshot
Roussoelins A and B: two phenols with antioxidant capacity from ascidian-derived fungus Roussoella siamensis SYSU-MS4723
inferred← citeshttps://doi.org/10.1016/9781855736160.3.147openalex-snapshot
Introducing natural antioxidants
inferred← citeshttps://doi.org/10.1016/b978-0-08-100596-5.21648-xopenalex-snapshot
Xanthine Oxidase in Dairy Foods
inferred← citeshttps://doi.org/10.1016/b978-0-12-373891-2.00082-1openalex-snapshot
Epicatechin and Its Role in Protection of LDL and of Vascular Endothelium
inferred← citeshttps://doi.org/10.1016/b978-0-12-373891-2.00085-7openalex-snapshot
Vasoactivity of Flavonols, Flavones and Catechins
inferred← citeshttps://doi.org/10.1016/b978-0-12-398456-2.00089-xopenalex-snapshot
Preventive Effects of Plant Polyphenols in the Promotion of Mammary Cancer and Testicular Damage Induced by Alcohol Drinking
inferred← citeshttps://doi.org/10.1016/b978-0-12-411462-3.00037-0openalex-snapshot
Bioactive Nutraceuticals and Stroke
inferred← citeshttps://doi.org/10.1016/b978-0-12-809762-5.00014-0openalex-snapshot
Nutrients in Cheese and Their Effect on Health and Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-813006-3.00027-1openalex-snapshot
Effects of Quercetin and Its Combinations on Health
inferred← citeshttps://doi.org/10.1016/b978-0-12-817903-1.00013-9openalex-snapshot
Bioactive natural products as potent inhibitors of xanthine oxidase
inferred← citeshttps://doi.org/10.1016/b978-0-323-91684-4.00002-5openalex-snapshot
Flavonoids: Chemistry, biosynthesis, isolation, and biological function
inferred← citeshttps://doi.org/10.1016/b978-0-443-33459-7.00006-5openalex-snapshot
Oxidative stress and cancer metabolism: From pathogenesis to therapeutic opportunities
inferred← citeshttps://doi.org/10.1016/b978-0-443-45193-5.00002-8openalex-snapshot
Sources of polyphenols and their occurrence
inferred← citeshttps://doi.org/10.1016/b978-0-444-64179-3.00012-8openalex-snapshot
Anticancer Potential of Flavonoids: Chemistry, Biological Activities, and Future Perspectives
inferred← citeshttps://doi.org/10.1016/b978-0-444-64181-6.00002-4openalex-snapshot
An Overview of Synthetic and Semisynthetic Flavonoid Derivatives and Analogues: Perspectives in Drug Discovery
inferred← citeshttps://doi.org/10.1016/b978-1-60805-999-7.50001-xopenalex-snapshot
Application of NMR Spectroscopy in Plant Polyphenols Associated with Human Health
inferred← citeshttps://doi.org/10.1016/j.ab.2014.02.018openalex-snapshot
Regioselective solvent-phase deuteration of polyphenolic compounds informs their identification by mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.ab.2023.115192openalex-snapshot
Simple assay for quantifying xanthine oxidase activity
inferred← citeshttps://doi.org/10.1016/j.abb.2007.10.012openalex-snapshot
Mono-O-methylated flavanols and other flavonoids as inhibitors of endothelial NADPH oxidase
inferred← citeshttps://doi.org/10.1016/j.aca.2009.01.037openalex-snapshot
Measurement of xanthine oxidase inhibition activity of phenolics and flavonoids with a modified cupric reducing antioxidant capacity (CUPRAC) method
inferred← citeshttps://doi.org/10.1016/j.aca.2011.12.003openalex-snapshot
Ultrahigh performance liquid chromatography–triple quadrupole mass spectrometry inhibitors fishing assay: A novel method for simultaneously screening of xanthine oxidase inhibitor and superoxide anion scavenger in a single analysis
inferred← citeshttps://doi.org/10.1016/j.aca.2017.07.023openalex-snapshot
A novel multi-hyphenated analytical method to simultaneously determine xanthine oxidase inhibitors and superoxide anion scavengers in natural products
inferred← citeshttps://doi.org/10.1016/j.algal.2017.05.008openalex-snapshot
Cuparane sesquiterpenes from Laurencia natalensis Kylin as inhibitors of alpha-glucosidase, dipeptidyl peptidase IV and xanthine oxidase
inferred← citeshttps://doi.org/10.1016/j.arabjc.2009.12.008openalex-snapshot
Radical scavenging and antioxidant activity of tannic acid
inferred← citeshttps://doi.org/10.1016/j.arabjc.2010.09.016openalex-snapshot
Antioxidant activity of clove oil – A powerful antioxidant source
inferred← citeshttps://doi.org/10.1016/j.arabjc.2011.06.016openalex-snapshot
Isolation and characterisation of flavonoids from the leaves of medicinal plant Orthosiphon stamineus
inferred← citeshttps://doi.org/10.1016/j.bbabio.2011.09.022openalex-snapshot
Complex I and cytochrome c are molecular targets of flavonoids that inhibit hydrogen peroxide production by mitochondria
inferred← citeshttps://doi.org/10.1016/j.bbagen.2003.10.010openalex-snapshot
Reactivity of flavonoids with 1-hydroxyethyl radical: a γ-radiolysis study
inferred← citeshttps://doi.org/10.1016/j.bbamem.2017.10.027openalex-snapshot
Interaction of a quercetin derivative - lensoside Aβ with liposomal membranes
inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.05.200openalex-snapshot
(–)-Epicatechin elevates nitric oxide in endothelial cells via inhibition of NADPH oxidase
inferred← citeshttps://doi.org/10.1016/j.bcp.2004.05.012openalex-snapshot
The flavones luteolin and apigenin inhibit in vitro antigen-specific proliferation and interferon-gamma production by murine and human autoimmune T cells
inferred← citeshttps://doi.org/10.1016/j.biocel.2013.10.004openalex-snapshot
Flavonoids as prospective compounds for anti-cancer therapy
inferred← citeshttps://doi.org/10.1016/j.biochi.2012.05.027openalex-snapshot
Differential suppression of intracellular reactive oxygen species-mediated signaling pathway in vascular endothelial cells by several subclasses of flavonoids
inferred← citeshttps://doi.org/10.1016/j.bionut.2014.07.005openalex-snapshot
Isolation of a bioactive flavonoid from Spilanthes calva D.C. in vitro xanthine oxidase assay and in silico study
inferred← citeshttps://doi.org/10.1016/j.bioorg.2017.08.001openalex-snapshot
Structure-activity relationships and molecular docking of thirteen synthesized flavonoids as horseradish peroxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.05.008openalex-snapshot
Hepatoprotective and antioxidant activity of quercetin loaded chitosan/alginate particles in vitro and in vivo in a model of paracetamol-induced toxicity
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.111151openalex-snapshot
Garcinia linii extracts exert the mediation of anti-diabetic molecular targets on anti-hyperglycemia
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.112442openalex-snapshot
RETRACTED: Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115548openalex-snapshot
Inhibition of xanthine oxidase-catalyzed xanthine and 6-mercaptopurine oxidation by luteolin, naringenin, myricetin, ampelopsin and their conjugated metabolites
inferred← citeshttps://doi.org/10.1016/j.bmc.2003.09.045openalex-snapshot
Structural requirements of flavonoids for inhibition of protein glycation and radical scavenging activities
inferred← citeshttps://doi.org/10.1016/j.bmc.2006.11.037openalex-snapshot
Improved quantitative structure–activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.01.058openalex-snapshot
A rational approach for the design and synthesis of 1-acetyl-3,5-diaryl-4,5-dihydro(1H)pyrazoles as a new class of potential non-purine xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmc.2011.07.039openalex-snapshot
N-(1,3-Diaryl-3-oxopropyl)amides as a new template for xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.04.048openalex-snapshot
Carboxylated aurone derivatives as potent inhibitors of xanthine oxidase
inferred← citeshttps://doi.org/10.1016/j.bmcl.2008.08.016openalex-snapshot
ortho-Dihydroxyisoflavone derivatives from aged Doenjang (Korean fermented soypaste) and its radical scavenging activity
inferred← citeshttps://doi.org/10.1016/j.bmcl.2013.12.031openalex-snapshot
Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2014.07.041openalex-snapshot
Synthesis and evaluation of naphthoflavones as a new class of non purine xanthine oxidase inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2015.06.016openalex-snapshot
An oxidative coupling product of luteolin with cysteine ester and its enhanced inhibitory activity for xanthine oxidase
inferred← citeshttps://doi.org/10.1016/j.carbpol.2016.07.027openalex-snapshot
Antioxidant and DNA damage protecting potentials of polysaccharide extracted from Phellinus baumii using a delignification method
inferred← citeshttps://doi.org/10.1016/j.cbi.2007.04.002openalex-snapshot
Transcriptional response of genes involved in cell defense system in human cells stressed by H2O2 and pre-treated with (Tunisian) Rhamnus alaternus extracts: Combination with polyphenolic compounds and classic in vitro assays
inferred← citeshttps://doi.org/10.1016/j.cbi.2012.04.003openalex-snapshot
Inhibitory effects of dietary flavonoids on purified hepatic NADH-cytochrome b5 reductase: Structure–activity relationships
inferred← citeshttps://doi.org/10.1016/j.cbi.2013.10.006openalex-snapshot
Biological evaluation of morin and its new oxovanadium(IV) complex as antio-xidant and specific anti-cancer agents
inferred← citeshttps://doi.org/10.1016/j.cbi.2014.02.003openalex-snapshot
Protective effects of neohesperidin dihydrochalcone against carbon tetrachloride-induced oxidative damage in vivo and in vitro
inferred← citeshttps://doi.org/10.1016/j.cbi.2014.05.010openalex-snapshot
Hispidin derived from Phellinus linteus affords protection against acrylamide-induced oxidative stress in Caco-2 cells
inferred← citeshttps://doi.org/10.1016/j.cbi.2023.110824openalex-snapshot
Aureusidin ameliorates 6-OHDA-induced neurotoxicity via activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway in SH-SY5Y cells and Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1016/j.chemphys.2016.06.006openalex-snapshot
Ab initio molecular dynamics of the reaction of quercetin with superoxide radical
inferred← citeshttps://doi.org/10.1016/j.chroma.2008.09.061openalex-snapshot
Antioxidant activity assays on-line with liquid chromatography
inferred← citeshttps://doi.org/10.1016/j.chroma.2010.07.042openalex-snapshot
Determination of polyphenolic compounds by liquid chromatography–mass spectrometry in Thymus species
inferred← citeshttps://doi.org/10.1016/j.clnesp.2019.10.017openalex-snapshot
Effect of dark chocolate on flow-mediated dilatation: Systematic review, meta-analysis, and dose–response analysis of randomized controlled trials
inferred← citeshttps://doi.org/10.1016/j.comptc.2016.06.021openalex-snapshot
Bond dissociation energies and enthalpies of formation of flavonoids: A G4 and M06-2X investigation
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