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Highly Efficient Synthesis of Isoquinolines via Nickel-Catalyzed Annulation of 2-Iodobenzaldimines with Alkynes: Evidence for Dual Pathways of Alkyne Insertion

https://doi.org/10.1021/ol0519994

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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inferred← citeshttps://doi.org/10.1021/ja904380qopenalex-snapshot

Isoquinoline Synthesis via Rhodium-Catalyzed Oxidative Cross-Coupling/Cyclization of Aryl Aldimines and Alkynes

inferred← citeshttps://doi.org/10.1021/jo060800dopenalex-snapshot

Nickel-Catalyzed Cyclization of 2-Iodoanilines with Aroylalkynes: An Efficient Route for Quinoline Derivatives

inferred← citeshttps://doi.org/10.1021/jo3010414openalex-snapshot

Synthesis of Isoquinolines and Heterocycle-Fused Pyridines via Three-Component Cascade Reaction of Aryl Ketones, Hydroxylamine, and Alkynes

inferred← citeshttps://doi.org/10.1021/jo400344mopenalex-snapshot

Primary Amines as Directing Groups in the Ru-Catalyzed Synthesis of Isoquinolines, Benzoisoquinolines, and Thienopyridines

inferred← citeshttps://doi.org/10.1021/jo501465qopenalex-snapshot

C–H Activation Guided by Aromatic N–H Ketimines: Synthesis of Functionalized Isoquinolines Using Benzyl Azides and Alkynes

inferred← citeshttps://doi.org/10.1021/jo8003259openalex-snapshot

A Tandem Approach to Isoquinolines from 2-Azido-3-arylacrylates and α-Diazocarbonyl Compounds

inferred← citeshttps://doi.org/10.1021/jo801761fopenalex-snapshot

Suzuki Cross-Coupling/Reductive Debenzyloxycarbonylation Sequence for the Syntheses of [c]Annulated Isoquinolines: Application for the Syntheses of Pancratistatin-like Isoquinolines

inferred← citeshttps://doi.org/10.1021/jo802196ropenalex-snapshot

Competition Studies in Alkyne Electrophilic Cyclization Reactions

inferred← citeshttps://doi.org/10.1021/jo900010mopenalex-snapshot

Synthesis of Isoquinoline Derivatives via Ag- Catalyzed Cyclization of 2-Alkynyl Benzyl Azides

inferred← citeshttps://doi.org/10.1021/jo902084jopenalex-snapshot

Easy Access to Isoquinolines and Tetrahydroquinolines from Ketoximes and Alkynes via Rhodium-Catalyzed C−H Bond Activation

inferred← citeshttps://doi.org/10.1021/ol101371copenalex-snapshot

Synthesis of Highly Substituted Isoquinolone Derivatives by Nickel-Catalyzed Annulation of 2-Halobenzamides with Alkynes

inferred← citeshttps://doi.org/10.1021/ol2018505openalex-snapshot

Synthesis of 1-Aminoisoquinolines via Rh(III)-Catalyzed Oxidative Coupling

inferred← citeshttps://doi.org/10.1021/ol301091zopenalex-snapshot

Ruthenium-Catalyzed Highly Regioselective Cyclization of Ketoximes with Alkynes by C–H Bond Activation: A Practical Route to Synthesize Substituted Isoquinolines

inferred← citeshttps://doi.org/10.1021/ol301273jopenalex-snapshot

Rhenium-Catalyzed Regioselective Synthesis of Multisubstituted Pyridines from β-Enamino Ketones and Alkynes via C–C Bond Cleavage

inferred← citeshttps://doi.org/10.1021/ol301445ropenalex-snapshot

Ru(II)-Catalyzed C–H Bond Activation for the Synthesis of Substituted Isoquinolinium Salts from Benzaldehydes, Amines, and Alkynes

inferred← citeshttps://doi.org/10.1021/ol402796mopenalex-snapshot

Synthesis of Isoquinolines via Rh(III)-Catalyzed C–H Activation Using Hydrazone as a New Oxidizing Directing Group

inferred← citeshttps://doi.org/10.1021/ol4030309openalex-snapshot

Modular Isoquinoline Synthesis Using Catalytic Enolate Arylation and in Situ Functionalization

inferred← citeshttps://doi.org/10.1021/ol501483kopenalex-snapshot

Rh-Catalyzed Sequential Oxidative C–H and N–N Bond Activation: Conversion of Azines into Isoquinolines with Air at Room Temperature

inferred← citeshttps://doi.org/10.1021/ol701784wopenalex-snapshot

Rapid Access to Pyrazolo[3,4-c]pyridines via Alkyne Annulation: Limitations of Steric Control in Nickel-Catalyzed Alkyne Insertions

inferred← citeshttps://doi.org/10.1021/ol800900aopenalex-snapshot

Assembly of Isoquinolines via CuI-Catalyzed Coupling of β-Keto Esters and 2-Halobenzylamines

inferred← citeshttps://doi.org/10.1021/ol8010826openalex-snapshot

Synthesis of 1(2H)-Isoquinolones by the Nickel-Catalyzed Denitrogenative Alkyne Insertion of 1,2,3-Benzotriazin-4(3H)-ones

inferred← citeshttps://doi.org/10.1021/om901088vopenalex-snapshot

Reactions of Cyclometalated Oxazoline Half-Sandwich Complexes of Iridium and Ruthenium with Alkynes and CO

inferred← citeshttps://doi.org/10.1039/b902095kopenalex-snapshot

Heterocyclization by catalytic carbonickelation of alkynes: a domino sequence involving vinylnickels

inferred← citeshttps://doi.org/10.1039/c0dt00280aopenalex-snapshot

Alkyne insertion into cyclometallated pyrazole and imine complexes of iridium, rhodium and ruthenium; relevance to catalytic formation of carbo- and heterocycles

inferred← citeshttps://doi.org/10.1039/c1ob05258fopenalex-snapshot

Synthesis of functionalized ellipticinium and ellipticine derivatives via electrophilic cyclization

inferred← citeshttps://doi.org/10.1039/c3cc41269eopenalex-snapshot

A regioselective synthesis of 1-haloisoquinolines via ruthenium-catalyzed cyclization of O-methylbenzohydroximoyl halides with alkynes

inferred← citeshttps://doi.org/10.1039/c3ra46722hopenalex-snapshot

Efficient synthesis of isoquinolines and pyridines via copper(i)-catalyzed multi-component reaction

inferred← citeshttps://doi.org/10.1039/c4cc09099copenalex-snapshot

Pd(0)-catalyzed chemoselective construction of spirocarbocycles via an alkyne insertion/β-naphthol dearomatization cascade

inferred← citeshttps://doi.org/10.1039/c4ra05026fopenalex-snapshot

Synthesis of substituted isoquinolines via iminoalkyne cyclization using Ag( i ) exchanged K10-montmorillonite clay as a reusable catalyst

inferred← citeshttps://doi.org/10.1039/c5cc03311jopenalex-snapshot

Ruthenium-catalyzed decarbonylative addition reaction of anhydrides with alkynes: a facile synthesis of isocoumarins and α-pyrones

inferred← citeshttps://doi.org/10.1039/c5ob01886bopenalex-snapshot

Rhodium( iii )-catalyzed annulation of arenes with alkynes assisted by an internal oxidizing N–O bond

inferred← citeshttps://doi.org/10.1039/c7ob02788eopenalex-snapshot

Palladium-catalysed stereoselective synthesis of 4-(diarylmethylidene)-3,4-dihydroisoquinolin-1(2 H )-ones: expedient access to 4-substituted isoquinolin-1(2 H )-ones and isoquinolines

inferred← citeshttps://doi.org/10.1039/c9cc03689jopenalex-snapshot

Harnessing the reactivity of ortho -formyl-arylketones: base-promoted regiospecific synthesis of functionalized isoquinolines

inferred← citeshttps://doi.org/10.1039/c9cs00539kopenalex-snapshot

Transition-metal-catalyzed reactions involving reductive elimination between dative ligands and covalent ligands

inferred← citeshttps://doi.org/10.1039/c9cy00009gopenalex-snapshot

Recent advances and prospects in nickel-catalyzed C–H activation

inferred← citeshttps://doi.org/10.1039/d0qo01097aopenalex-snapshot

Ni-Catalyzed stereoselective difunctionalization of alkynes

inferred← citeshttps://doi.org/10.1039/d2ob00513aopenalex-snapshot

Nickel-catalyzed [2 + 2 + 2] benzannulation of alkynes: a new route to the synthesis of highly substituted naphthalenes

inferred← citeshttps://doi.org/10.1039/d6ra01670gopenalex-snapshot

Rh( iii )-catalyzed oxidative C–H annulation of 6-arylpyridazin-3(2 H )-ones: direct access to diarylpyridazino[6,1- a ]isoquinolin-5-ium-3-olates

inferred← citeshttps://doi.org/10.1055/sos-sd-115-00651openalex-snapshot

15.5.4 Isoquinolines (Update 2019)

inferred← citeshttps://doi.org/10.1080/00397911.2019.1568499openalex-snapshot

Nickel catalysis: six membered heterocycle syntheses

inferred← citeshttps://doi.org/10.1134/s1070427210050253openalex-snapshot

Polymerization of styrene and methyl methacrylate using a catalytic system based on 1,2–bis(diphenylphosphino)ethanenickel dibromide

inferred← citeshttps://doi.org/10.1246/bcsj.79.1126openalex-snapshot

New Synthesis of Isoquinoline and 3,4-Dihydroisoquinoline Derivatives

inferred← citeshttps://doi.org/10.1246/cl.2011.600openalex-snapshot

Rhodium-catalyzed Oxidative Coupling of Benzylamines with Alkynes through Dehydrogenation and Dehydrogenative Cyclization

inferred← citeshttps://doi.org/10.1246/cl.2012.798openalex-snapshot

Synthesis of (1H)-Isochromen-1-imines by Nickel-catalyzed Reaction of 2-Iodobenzamides with Alkynes

inferred← citeshttps://doi.org/10.3184/174751913x13744287541024openalex-snapshot

A Selective Synthesis of 4-Bromoisoquinoline and 4-Bromoisquinolone

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