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Cytotoxic Action of Juglone and Plumbagin: A Mechanistic Study Using HaCaT Keratinocytes
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Electron Paramagnetic Resonance
inferredcites →https://doi.org/10.1006/jmrb.1994.1062openalex-snapshot
Simulation of Multiple Isotropic Spin-Trap EPR Spectra
inferredcites →https://doi.org/10.1016/0003-9861(80)90323-9openalex-snapshot
Spin trapping of superoxide and hydroxyl radical: Practical aspects
inferredcites →https://doi.org/10.1016/0003-9861(83)90244-8openalex-snapshot
Hepatic low-level chemiluminescence during redox cycling of menadione and the menadione-glutathione conjugate: Relation to glutathione and NAD(P)H:quinone reductase (DT-diaphorase) activity
inferredcites →https://doi.org/10.1016/0003-9861(86)90047-0openalex-snapshot
Quinone toxicity in hepatocytes without oxidative stress
inferredcites →https://doi.org/10.1016/0003-9861(87)90006-3openalex-snapshot
Formation of glutathione-conjugated semiquinones by the reaction of quinones with glutathione: An ESR study
inferredcites →https://doi.org/10.1016/0006-2952(86)90544-7openalex-snapshot
Overview of enzyme systems involved in bioreduction of drugs and in redox cycling
inferredcites →https://doi.org/10.1016/0167-4838(93)90198-zopenalex-snapshot
The one-electron reduction potential of several substrates can be related to their reduction rates by cytochrome P-450 reductase
inferredcites →https://doi.org/10.1016/s0021-9258(18)54666-4openalex-snapshot
Effect of hydroxy substituent position on 1,4-naphthoquinone toxicity to rat hepatocytes.
inferredcites →https://doi.org/10.1021/j100860a005openalex-snapshot
High-resolution electron spin resonance studies of hyperfine interactions in substituted 1,4-naphthoquinones and naphthazarins
inferredcites →https://doi.org/10.1021/jf60221a027openalex-snapshot
Identification of juglone in pecan as a possible factor of resistance to Fusicladium effusum
inferredcites →https://doi.org/10.1046/j.1523-1747.2002.00077.xopenalex-snapshot
Parameters Related to Oxygen Free Radicals in Human Skin: A Study Comparing Healthy Epidermis and Skin Cancer Tissue
inferredcites →https://doi.org/10.1083/jcb.106.3.761openalex-snapshot
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Recent advances in polyphenol oxidase-mediated plant stress responses
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Derivatization of 2,3-Dihalo-1,4-Naphthoquinone Compounds (DHNQ’S) and Their Electrochemistry and In-Situ Spectroelectrochemistry Properties
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Naphthoquinones and Anthraquinones: Chemical, Analytical, and Biological Overview
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Investigation of the antimicrobial and anticancer activity of aminonaphthoquinones
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Highly Efficient Synthesis and Structure–Activity Relationships of a Small Library of Substituted 1,4‐Naphthoquinones
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Direct Functionalization of para‐Quinones: A Historical Review and New Perspectives
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Electrogeneration of O2.− and H2O2 Using Polymer‐modified Microelectrodes in the Environment of Living Cells
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Different Derivatives of Plumbagin Analogue: Bioavailability and Their Toxicity Studies
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Plumbagin inhibits proliferative and inflammatory responses of T cells independent of ROS generation but by modulating intracellular thiols
inferred← citeshttps://doi.org/10.1002/jcb.28296openalex-snapshot
Overexpression of Hes1 is involved in sensitization of K562 cells to Imatinib
inferred← citeshttps://doi.org/10.1002/jsfa.5522openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/med.20235openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/pros.22585openalex-snapshot
The combination of plumbagin with androgen withdrawal causes profound regression of prostate tumors in vivo
inferred← citeshttps://doi.org/10.1002/ptr.2343openalex-snapshot
Antimycobacterial activity of Juglans regia, Juglans mollis, Carya illinoensis and Bocconia frutescens
inferred← citeshttps://doi.org/10.1002/ptr.5650openalex-snapshot
Plumbagin, a Plant-Derived Compound, Exhibits Antifungal Combinatory Effect with Amphotericin B againstCandida albicansClinical Isolates and Anti-hepatitis C Virus Activity
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Synthesis of Quinone‐Based N ‐Sulfonyl‐1,2,3‐triazoles: Chemical Reactivity of Rh(II) Azavinyl Carbenes and Antitumor Activity
inferred← citeshttps://doi.org/10.1002/tox.24002openalex-snapshot
Demethoxymurrapanine, an indole‐naphthoquinone alkaloid, inhibits the proliferation of oral cancer cells without major side effects on normal cells
inferred← citeshttps://doi.org/10.1007/0-387-33016-x_21openalex-snapshot
Green Fluorescent Protein as a Biosensor for Toxic Compounds
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Dermal Toxicity and Environmental Contamination: Electron Transfer, Reactive Oxygen Species, Oxidative Stress, Cell Signaling, and Protection by Antioxidants
inferred← citeshttps://doi.org/10.1007/978-3-030-91499-8_12openalex-snapshot
Transcription Factors That Scavenge Reactive Oxygen Species in Rhizobacteria
inferred← citeshttps://doi.org/10.1007/978-981-19-9936-9_15openalex-snapshot
Occurrence and Diversity of Major Naphthoquinones in Higher Plants: Their Distribution and Conservation Strategies
inferred← citeshttps://doi.org/10.1007/bf02977337openalex-snapshot
Synthesis and antifungal activity of naphthalene-1,4-diones modified at positions 2, 3, and 5
inferred← citeshttps://doi.org/10.1007/bf03175528openalex-snapshot
Allelochemicals: sources, toxicity and microbial transformation in soil —a review
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inferred← citeshttps://doi.org/10.1007/s00049-019-00288-yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s00204-012-0872-9openalex-snapshot
7-Nitro-4-(phenylthio)benzofurazan is a potent generator of superoxide and hydrogen peroxide
inferred← citeshttps://doi.org/10.1007/s00204-014-1382-8openalex-snapshot
Xenobiotic-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
inferred← citeshttps://doi.org/10.1007/s00204-018-2232-xopenalex-snapshot
Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
inferred← citeshttps://doi.org/10.1007/s00216-006-0502-6openalex-snapshot
UV/Vis spectra and solubility of some naphthoquinones, and the extraction behavior of plumbagin from Plumbago scandens roots in supercritical CO2
inferred← citeshttps://doi.org/10.1007/s00726-005-0298-2openalex-snapshot
When quinones meet amino acids: chemical, physical and biological consequences
inferred← citeshttps://doi.org/10.1007/s10156-005-0427-6openalex-snapshot
Evaluation of the effect of terpenoid quinones on Trichophyton mentagrophytes by solution and vapor contact
inferred← citeshttps://doi.org/10.1007/s10495-016-1259-9openalex-snapshot
Plumbagin, a plant-derived naphthoquinone metabolite induces mitochondria mediated apoptosis-like cell death in Leishmania donovani: an ultrastructural and physiological study
inferred← citeshttps://doi.org/10.1007/s10522-017-9742-4openalex-snapshot
Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1007/s10811-015-0686-2openalex-snapshot
A field application feasibility assessment of naphthoquinone derivatives for the mitigation of freshwater diatom Stephanodiscus blooms
inferred← citeshttps://doi.org/10.1007/s10886-011-0015-4openalex-snapshot
Ability of the Oriental Fruit Moth Grapholita molesta (Lepidoptera: Tortricidae) to Detoxify Juglone, the Main Secondary Metabolite of the Non-host Plant Walnut
inferred← citeshttps://doi.org/10.1007/s10934-025-01898-4openalex-snapshot
Development and assessment of amine-functionalized KIT-6 for In Vitro drug delivery using Juglone as the therapeutic agent
inferred← citeshttps://doi.org/10.1007/s11240-014-0547-8openalex-snapshot
Enhanced plumbagin accumulation in embryogenic cell suspension cultures of Plumbago rosea L. following elicitation
inferred← citeshttps://doi.org/10.1007/s11418-019-01309-4openalex-snapshot
A new triterpene from the green walnut husks of Juglans mandshurica Maxim
inferred← citeshttps://doi.org/10.1007/s11434-006-2077-1openalex-snapshot
Bioeffects of different functionalized silica nanoparticles on HaCaT cell line
inferred← citeshttps://doi.org/10.1007/s11626-015-9961-4openalex-snapshot
Augmentation of oxidative stress-induced apoptosis in MCF7 cells by ascorbate–tamoxifen and/or ascorbate–juglone treatments
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Carnivorous Plants as a Source of Potent Bioactive Compound: Naphthoquinones
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Characterization of lapachol cytotoxicity: contribution of glutathione depletion for oxidative stress in Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1007/s12257-013-0284-6openalex-snapshot
Combination of 1,4-naphthoquinone with benzothiazoles had selective algicidal effects against harmful algae
inferred← citeshttps://doi.org/10.1007/s12272-019-01160-xopenalex-snapshot
A new anti-Helicobacter pylori juglone from Reynoutria japonica
inferred← citeshttps://doi.org/10.1007/s12272-020-01221-6openalex-snapshot
Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction
inferred← citeshttps://doi.org/10.1007/s12668-024-01429-6openalex-snapshot
Formulation and Evaluation of Pluronic F-127 Thermoresponsive Nanogels Containing Juglone for In vivo Wound Healing Potential
inferred← citeshttps://doi.org/10.1007/s13258-010-0145-zopenalex-snapshot
Apoptotic effect of Naphthoquinone derivatives on HCT116 colon cancer cells
inferred← citeshttps://doi.org/10.1007/s13738-017-1094-0openalex-snapshot
Investigating the interaction of juglone (5-hydroxy-1, 4-naphthoquinone) with serum albumins using spectroscopic and in silico methods
inferred← citeshttps://doi.org/10.1016/b978-0-12-812373-7.00016-4openalex-snapshot
Chemopreventive and Anticancer Effects of Plumbagin: Novel Mechanism(s) via Modulation of Cellular Redox
inferred← citeshttps://doi.org/10.1016/b978-0-323-90219-9.00003-0openalex-snapshot
Thiol targets in drug development to combat bacterial infections
inferred← citeshttps://doi.org/10.1016/b978-0-323-99598-6.00023-2openalex-snapshot
Sustainable moth repellent finishing for wool
inferred← citeshttps://doi.org/10.1016/b978-0-444-63294-4.00005-xopenalex-snapshot
Bioactive Naphthoquinones from Higher Plants
inferred← citeshttps://doi.org/10.1016/j.abb.2010.02.002openalex-snapshot
1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes
inferred← citeshttps://doi.org/10.1016/j.abb.2012.04.014openalex-snapshot
Why do bacteria use so many enzymes to scavenge hydrogen peroxide?
inferred← citeshttps://doi.org/10.1016/j.abb.2017.02.007openalex-snapshot
Targeting thioredoxin reductase by plumbagin contributes to inducing apoptosis of HL-60 cells
inferred← citeshttps://doi.org/10.1016/j.atmosenv.2025.121189openalex-snapshot
The photochemistry of quinones and combustion-derived particles in forming hydroxyl radicals and singlet oxygen in the atmosphere
inferred← citeshttps://doi.org/10.1016/j.bbabio.2022.148558openalex-snapshot
The aprotic electrochemistry of quinones
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A fluorescence-based rapid screening assay for cytotoxic compounds
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Tandem screening of toxic compounds on GFP-labeled bacteria and cancer cells in microtiter plates
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.03.092openalex-snapshot
Plumbagin exerts an immunosuppressive effect on human T-cell acute lymphoblastic leukemia MOLT-4 cells
inferred← citeshttps://doi.org/10.1016/j.bcp.2010.02.009openalex-snapshot
Mode of action of Nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi: Is oxidative stress involved?
inferred← citeshttps://doi.org/10.1016/j.biocel.2018.01.004openalex-snapshot
Novel 1,4-naphthoquinone derivatives induce apoptosis via ROS-mediated p38/MAPK, Akt and STAT3 signaling in human hepatoma Hep3B cells
inferred← citeshttps://doi.org/10.1016/j.bioelechem.2011.12.010openalex-snapshot
Electrochemical strategy to scout 1,4-naphthoquinones effect on voltage gated potassium channels
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.112785openalex-snapshot
Molecular biological mechanism of action in cancer therapies: Juglone and its derivatives, the future of development
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Elucidation of structure–activity relationships for 2- or 6-substituted-5,8-dimethoxy-1,4-naphthoquinones
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A laccase-catalysed one-pot synthesis of aminonaphthoquinones and their anticancer activity
inferred← citeshttps://doi.org/10.1016/j.bmc.2013.12.007openalex-snapshot
The cytotoxic effect of 2-acylated-1,4-naphthohydroquinones on leukemia/lymphoma cells
inferred← citeshttps://doi.org/10.1016/j.bmc.2020.115878openalex-snapshot
Design, synthesis and biological evaluation of novel thiazole-based derivatives as human Pin1 inhibitors
inferred← citeshttps://doi.org/10.1016/j.bmcl.2011.08.095openalex-snapshot
Micelles catalyzed chemoselective synthesis ‘in water’ and biological evaluation of oxygen containing hetero-1,4-naphthoquinones as potential antifungal agents
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.04.009openalex-snapshot
Synthesis, reactive oxygen species generation and copper-mediated nuclease activity profiles of 2-aryl-3-amino-1,4-naphthoquinones
inferred← citeshttps://doi.org/10.1016/j.bmcl.2014.02.018openalex-snapshot
Synthesis and antiproliferative evaluation of 13-aryl-13H-benzo[g]benzothiazolo [2,3-b]quinazoline-5,14-diones
inferred← citeshttps://doi.org/10.1016/j.bmcl.2018.04.060openalex-snapshot
Investigation of chemical reactivity of 2-alkoxy-1,4-naphthoquinones and their anticancer activity
inferred← citeshttps://doi.org/10.1016/j.burns.2020.06.032openalex-snapshot
Investigating the effects of walnut ointment on non-healing burn wounds
inferred← citeshttps://doi.org/10.1016/j.canlet.2014.11.031openalex-snapshot
Plumbagin induces apoptosis in lymphoma cells via oxidative stress mediated glutathionylation and inhibition of mitogen-activated protein kinase phosphatases (MKP1/2)
inferred← citeshttps://doi.org/10.1016/j.cclet.2024.109626openalex-snapshot
Fe(III)-juglone nanoscale coordination polymers for cascade chemodynamic therapy through synergistic ferroptosis and apoptosis strategy
inferred← citeshttps://doi.org/10.1016/j.ccr.2025.216847openalex-snapshot
First-row transition metal complexes of naturally occurring anticancer chelators for cancer treatment
inferred← citeshttps://doi.org/10.1016/j.cej.2021.133057openalex-snapshot
Juglone-loaded metal-organic frameworks for H2O2 self-modulating enhancing chemodynamic therapy against prostate cancer
inferred← citeshttps://doi.org/10.1016/j.cellbi.2009.06.018openalex-snapshot
Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells
inferred← citeshttps://doi.org/10.1016/j.cellsig.2013.05.026openalex-snapshot
Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2019.110754openalex-snapshot
Toxicological evaluation of naringin-loaded nanocapsules in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.comptc.2023.114077openalex-snapshot
Adsorption of juglone on pure and boron-doped C24 fullerene-like nano-cage: A density functional theory investigation
inferred← citeshttps://doi.org/10.1016/j.dyepig.2012.11.020openalex-snapshot
Investigation on the dyeing power of some organic natural compounds for a green approach to hair dyeing
inferred← citeshttps://doi.org/10.1016/j.ejmcr.2024.100194openalex-snapshot
Current status of 1,4-Naphthoquinones and their derivatives for wound healing
inferred← citeshttps://doi.org/10.1016/j.ejmech.2004.12.004openalex-snapshot
Synthesis and antifungal activity of 2/3-arylthio- and 2,3-bis(arylthio)-5-hydroxy-/5-methoxy-1,4-naphthoquinones
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.06.012openalex-snapshot
Synthesis and anticancer activity of some novel 5,6-fused hybrids of juglone based 1,4-naphthoquinones
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.07.024openalex-snapshot
Synthesis, anticancer activity and QSAR study of 1,4-naphthoquinone derivatives
inferred← citeshttps://doi.org/10.1016/j.ejmech.2026.118726openalex-snapshot
DFT guided design of novel quinone bioisosteres as inhibitors of the clathrin N-terminal domain-amphiphysin protein-protein interaction. Dihydroquinazolin-4(1H)-ones and quinazolin-3(4H)-ones
inferred← citeshttps://doi.org/10.1016/j.ejphar.2010.04.016openalex-snapshot
Plumbagin activates ERK1/2 and Akt via superoxide, Src and PI3-kinase in 3T3-L1 Cells
inferred← citeshttps://doi.org/10.1016/j.ejphar.2010.06.072openalex-snapshot
Anti-proliferative effect of Juglone from Juglans mandshurica Maxim on human leukemia cell HL-60 by inducing apoptosis through the mitochondria-dependent pathway
inferred← citeshttps://doi.org/10.1016/j.electacta.2013.05.123openalex-snapshot
The stabilizing role of intramolecular hydrogen bonding in disubstituted hydroxy-quinones
inferred← citeshttps://doi.org/10.1016/j.electacta.2014.12.148openalex-snapshot
Electropolymerization of quinone-polymers onto grafted quinone monolayers: a route towards non-passivating, catalytically active film
inferred← citeshttps://doi.org/10.1016/j.envexpbot.2015.01.005openalex-snapshot
DNA hypomethylation concomitant with the overproduction of ROS induced by naphthoquinone juglone on tobacco BY-2 suspension cells
inferred← citeshttps://doi.org/10.1016/j.etap.2005.11.003openalex-snapshot
Glyphosate-induced antioxidant imbalance in HaCaT: The protective effect of Vitamins C and E
inferred← citeshttps://doi.org/10.1016/j.exppara.2015.09.005openalex-snapshot
Juglone induces cell death of Acanthamoeba through increased production of reactive oxygen species
inferred← citeshttps://doi.org/10.1016/j.fct.2012.01.002openalex-snapshot
Juglone, from Juglans mandshruica Maxim, inhibits growth and induces apoptosis in human leukemia cell HL-60 through a reactive oxygen species-dependent mechanism
inferred← citeshttps://doi.org/10.1016/j.fct.2013.11.027openalex-snapshot
Plumbagin inhibits LPS-induced inflammation through the inactivation of the nuclear factor-kappa B and mitogen activated protein kinase signaling pathways in RAW 264.7 cells
inferred← citeshttps://doi.org/10.1016/j.fct.2019.01.018openalex-snapshot
Emerging role of plumbagin: Cytotoxic potential and pharmaceutical relevance towards cancer therapy
inferred← citeshttps://doi.org/10.1016/j.fitote.2025.106380openalex-snapshot
Effects on neuroprotection and α-synuclein expression of a Canna coccinea rhizome extract
inferred← citeshttps://doi.org/10.1016/j.foodres.2011.06.056openalex-snapshot
Resistance and survival strategies of Salmonella enterica to environmental stresses
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2011.09.009openalex-snapshot
Plumbagin and juglone induce caspase-3-dependent apoptosis involving the mitochondria through ROS generation in human peripheral blood lymphocytes
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.02.013openalex-snapshot
Details in the catalytic mechanism of mammalian thioredoxin reductase 1 revealed using point mutations and juglone-coupled enzyme activities
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.04.004openalex-snapshot
Uncoupling of oxidative stress resistance and lifespan in long-lived isp-1 mitochondrial mutants in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.09.001openalex-snapshot
Modulation of Caspase-3 activity using a redox active vitamin K3 analogue, plumbagin, as a novel strategy for radioprotection
inferred← citeshttps://doi.org/10.1016/j.heliyon.2021.e06044openalex-snapshot
1H and 13C NMR chemical shifts of 2-n-alkylamino-naphthalene-1,4-diones
inferred← citeshttps://doi.org/10.1016/j.ica.2019.119361openalex-snapshot
Cytotoxicity and reactivity of a redox active 1,4-quinone-pyrazole compound and its Ru(II)-p-cymene complex
inferred← citeshttps://doi.org/10.1016/j.indcrop.2014.08.038openalex-snapshot
Luehea divaricata Mart. anticholinesterase and antioxidant activity in a Caenorhabditis elegans model system
inferred← citeshttps://doi.org/10.1016/j.indcrop.2019.06.005openalex-snapshot
Antifungal activity of Juglans spp. and Carya sp. ethanol extracts against Fusarium oxysporum on tomato under greenhouse conditions
inferred← citeshttps://doi.org/10.1016/j.inoche.2025.114333openalex-snapshot
Synthesis, characterization and preliminary biological evaluation of novel Hg(PLB)2 and Cr(PLB)3 complexes
inferred← citeshttps://doi.org/10.1016/j.jab.2015.07.003openalex-snapshot
Radiosensitizing potential of Plumbagin in B16F1 melanoma tumor cells through mitochondrial mediated programmed cell death
inferred← citeshttps://doi.org/10.1016/j.jelechem.2004.12.036openalex-snapshot
Intra and intermolecular hydrogen bonding effects in the electrochemical reduction of α-phenolic-naphthoquinones
inferred← citeshttps://doi.org/10.1016/j.jelechem.2023.117913openalex-snapshot
Electrochemistry and in-situ spectroelectrochemistry properties of N-, S-substituted-1,4-naphthoquinone compounds (NQ’s)
inferred← citeshttps://doi.org/10.1016/j.jff.2020.104198openalex-snapshot
Trehalose against UVB-induced skin photoaging by suppressing MMP expression and enhancing procollagen I synthesis in HaCaT cells
inferred← citeshttps://doi.org/10.1016/j.jics.2021.100005openalex-snapshot
Influence of dipole moments on the medicinal activities of diverse organic compounds
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2014.04.020openalex-snapshot
Ferrocene and (arene)ruthenium(II) complexes of the natural anticancer naphthoquinone plumbagin with enhanced efficacy against resistant cancer cells and a genuine mode of action
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2019.110950openalex-snapshot
SOD activity of new copper II complexes with ligands derived from pyridoxal and toxicity in Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1016/j.jphotobiol.2019.01.015openalex-snapshot
Eco-friendly walnut shell powder based facile fabrication of biogenic Ag-nanodisks, and their interaction with bovine serum albumin
inferred← citeshttps://doi.org/10.1016/j.jphotobiol.2019.02.006openalex-snapshot
Binding Interaction of Juglone with Lysozyme: Spectroscopic Studies Aided by In Silico Calculations
inferred← citeshttps://doi.org/10.1016/j.leukres.2011.06.018openalex-snapshot
Plumbagin treatment leads to apoptosis in human K562 leukemia cells through increased ROS and elevated TRAIL receptor expression
inferred← citeshttps://doi.org/10.1016/j.mad.2009.02.004openalex-snapshot
Increased age reduces DAF-16 and SKN-1 signaling and the hormetic response of Caenorhabditis elegans to the xenobiotic juglone
inferred← citeshttps://doi.org/10.1016/j.molpha.2025.100050openalex-snapshot
Molecular and cellular effects of hydroxy-1,4 naphthoquinones used in dermatological and cosmetic applications on human protein tyrosine phosphatase PTP1B in human keratinocytes
inferred← citeshttps://doi.org/10.1016/j.molstruc.2008.04.002openalex-snapshot
Desmotropy in reduced plumbagins: α- and β-Dihydroplumbagins
inferred← citeshttps://doi.org/10.1016/j.molstruc.2014.12.025openalex-snapshot
The discovery of bioisoster compound for plumbagin using the knowledge-based rational method
inferred← citeshttps://doi.org/10.1016/j.molstruc.2017.08.082openalex-snapshot
Synthesis, molecular docking, DFT calculations and cytotoxicity activity of benzo[g]quinazoline derivatives in choline chloride-urea
inferred← citeshttps://doi.org/10.1016/j.mrgentox.2013.05.007openalex-snapshot
Antimutagenic and antioxidant properties of plumbagin and other naphthoquinones
inferred← citeshttps://doi.org/10.1016/j.neulet.2017.01.007openalex-snapshot
5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain
inferred← citeshttps://doi.org/10.1016/j.phymed.2020.153449openalex-snapshot
Juglone prevents human platelet aggregation through inhibiting Akt and protein disulfide isomerase
inferred← citeshttps://doi.org/10.1016/j.phymed.2021.153598openalex-snapshot
The triterpenoid ursolic acid ameliorates stress in Caenorhabditis elegans by affecting the depression-associated genes skn-1 and prdx2
inferred← citeshttps://doi.org/10.1016/j.phytochem.2006.06.015openalex-snapshot
Computation of the redox and protonation properties of quinones: Towards the prediction of redox cycling natural products
inferred← citeshttps://doi.org/10.1016/j.phytochem.2017.09.012openalex-snapshot
The oxidative stress in allelopathy: Participation of prenyllipid antioxidants in the response to juglone in Chlamydomonas reinhardtii
inferred← citeshttps://doi.org/10.1016/j.phytol.2018.07.032openalex-snapshot
Antimycobacterial 1,4-napthoquinone natural products from Moneses uniflora
inferred← citeshttps://doi.org/10.1016/j.plaphy.2023.107660openalex-snapshot
Impact of cytotoxic plant naphthoquinones, juglone, plumbagin, lawsone and 2-methoxy-1,4-naphthoquinone, on Chlamydomonas reinhardtii reveals the biochemical mechanism of juglone toxicity by rapid depletion of plastoquinol
inferred← citeshttps://doi.org/10.1016/j.pupt.2013.08.001openalex-snapshot
Naphthoquinones isolated from Diospyros anisandra exhibit potent activity against pan-resistant first-line drugs Mycobacterium tuberculosis strains
inferred← citeshttps://doi.org/10.1016/j.rechem.2023.101138openalex-snapshot
A review on the synthesis and application of naphthoquinone-based drugs
inferred← citeshttps://doi.org/10.1016/j.redox.2026.104274openalex-snapshot
Ascorbate-driven quinone redox cycling as a pro-oxidant anticancer strategy
inferred← citeshttps://doi.org/10.1016/j.saa.2021.119998openalex-snapshot
Study the interaction between juglone and calf thymus DNA by spectroscopic and molecular docking techniques
inferred← citeshttps://doi.org/10.1016/j.taap.2005.03.005openalex-snapshot
The natural toxin juglone causes degradation of p53 and induces rapid H2AX phosphorylation and cell death in human fibroblasts
inferred← citeshttps://doi.org/10.1016/j.taap.2007.05.018openalex-snapshot
Induction of apoptosis by plumbagin through reactive oxygen species-mediated inhibition of topoisomerase II
inferred← citeshttps://doi.org/10.1016/j.taap.2010.05.013openalex-snapshot
Plumbagin-induced apoptosis in lymphocytes is mediated through increased reactive oxygen species production, upregulation of Fas, and activation of the caspase cascade
inferred← citeshttps://doi.org/10.1016/j.tet.2017.09.025openalex-snapshot
Diels-Alder reactions of fused 5-, 6- and 7-membered ring 2-vinylindoles: Synthesis of annulated tetrahydrocarbazoles
inferred← citeshttps://doi.org/10.1016/j.tet.2019.05.066openalex-snapshot
CuI/Cu(OTf)2/DMSO system-catalyzed intramolecular oxidative cyclization of (o-alkynyl)arylketones: Efficient synthesis of 1,4-naphthoquinones
inferred← citeshttps://doi.org/10.1016/j.tetlet.2013.05.035openalex-snapshot
Ethyl lactate as a promising bio based green solvent for the synthesis of spiro-oxindole derivatives via 1,3-dipolar cycloaddition reaction
inferred← citeshttps://doi.org/10.1016/j.theochem.2009.09.024openalex-snapshot
A DFT study on the radical scavenging activity of juglone and its derivatives
inferred← citeshttps://doi.org/10.1016/j.tim.2020.10.001openalex-snapshot
How Microbes Evolved to Tolerate Oxygen
inferred← citeshttps://doi.org/10.1016/j.tiv.2009.11.018openalex-snapshot
Effect of hydroxy substituent on the prooxidant action of naphthoquinone compounds
inferred← citeshttps://doi.org/10.1016/j.tiv.2011.12.007openalex-snapshot
Possible mechanism of superoxide formation through redox cycling of plumbagin in pig heart
inferred← citeshttps://doi.org/10.1016/j.tiv.2013.08.002openalex-snapshot
Novel o-naphthoquinones induce apoptosis of EL-4 T lymphoma cells through the increase of reactive oxygen species
inferred← citeshttps://doi.org/10.1016/j.tiv.2016.12.005openalex-snapshot
An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens
inferred← citeshttps://doi.org/10.1016/j.tiv.2020.104788openalex-snapshot
Prooxidative activity of plumbagin induces apoptosis in human pancreatic ductal adenocarcinoma cells via intrinsic apoptotic pathway
inferred← citeshttps://doi.org/10.1016/j.toxrep.2015.06.010openalex-snapshot
Protective effects of novel organic selenium compounds against oxidative stress in the nematode Caenorhabditis elegans
inferred← citeshttps://doi.org/10.1016/j.vph.2009.06.007openalex-snapshot
TW96, a synthetic 1,4-naphthoquinone, differentially regulates vascular and endothelial cells survival
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.6b00256openalex-snapshot
Formation and Biological Targets of Quinones: Cytotoxic versus Cytoprotective Effects
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.7b00127openalex-snapshot
The Dihydroxy Metabolite of the Teratogen Thalidomide Causes Oxidative DNA Damage
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.9b00428openalex-snapshot
Interactions of TiO2 Nanoparticles with Ingredients from Modern Lifestyle Products and Their Effects on Human Skin Cells
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c02107openalex-snapshot
Discovery of 5-Hydroxy-1,4-naphthoquinone (Juglone) Derivatives as Dual Effective Agents Targeting Platelet-Cancer Interplay through Protein Disulfide Isomerase Inhibition
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.7b00914openalex-snapshot
Synthesis, Characterization, and Evaluation of Triptolide Cell-Penetrating Peptide Derivative for Transdermal Delivery of Triptolide
inferred← citeshttps://doi.org/10.1021/acsomega.2c06691openalex-snapshot
Copper-Plumbagin Complex Produces Potent Anticancer Effects by Depolymerizing Microtubules and Inducing Reactive Oxygen Species and DNA Damage
inferred← citeshttps://doi.org/10.1021/acssuschemeng.7b00039openalex-snapshot
Naphthoquinones from Walnut Husk Residues Show Strong Nematicidal Activities against the Root-knot Nematode Meloidogyne hispanica
inferred← citeshttps://doi.org/10.1038/aps.2017.19openalex-snapshot
Plumbagin suppresses chronic periodontitis in rats via down-regulation of TNF-α, IL-1β and IL-6 expression
inferred← citeshttps://doi.org/10.1038/hortres.2016.46openalex-snapshot
Biosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plants
inferred← citeshttps://doi.org/10.1038/s41598-018-19261-wopenalex-snapshot
Oxidative stress via inhibition of the mitochondrial electron transport and Nrf-2-mediated anti-oxidative response regulate the cytotoxic activity of plumbagin
inferred← citeshttps://doi.org/10.1038/s41598-018-19964-0openalex-snapshot
Application of Sustainable Natural Resources in Agriculture: Acaricidal and Enzyme Inhibitory Activities of Naphthoquinones and Their Analogs against Psoroptes cuniculi
inferred← citeshttps://doi.org/10.1039/b822684aopenalex-snapshot
Towards a molecular-level understanding of the reactivity differences for radical anions of juglone and plumbagin: an electrochemical and spectroelectrochemical approach
inferred← citeshttps://doi.org/10.1039/c2ee21594bopenalex-snapshot
Bioelectrical redox cycling of anthraquinone-2,6-disulfonate coupled to perchlorate reduction
inferred← citeshttps://doi.org/10.1039/c4mt00165fopenalex-snapshot
Caging of plumbagin on silver nanoparticles imparts selectivity and sensitivity to plumbagin for targeted cancer cell apoptosis
inferred← citeshttps://doi.org/10.1039/c4ra13547dopenalex-snapshot
Understanding cancer and the anticancer activities of naphthoquinones – a review
inferred← citeshttps://doi.org/10.1039/c4ra16372aopenalex-snapshot
l -Proline catalyzed three-component synthesis of para-naphthoquinone–4-aza-podophyllotoxin hybrids as potent antitumor agents
inferred← citeshttps://doi.org/10.1039/c5ay02993gopenalex-snapshot
Girard reagent purification coupled with hollow-fiber-based stirring liquid microextraction followed by HPLC with diode array detection for determination of naphthoquinones in Qing Long Yi
inferred← citeshttps://doi.org/10.1039/c7ra10490aopenalex-snapshot
Naphthoquinone based chemosensors for transition metal ions: experiment and theory
inferred← citeshttps://doi.org/10.1039/d0dt01091jopenalex-snapshot
Ru( ii )-Naphthoquinone complexes with high selectivity for triple-negative breast cancer
inferred← citeshttps://doi.org/10.1039/d1cb00259gopenalex-snapshot
Laccase-mediated synthesis of bioactive natural products and their analogues
inferred← citeshttps://doi.org/10.1039/d1fo02128aopenalex-snapshot
Pyrroloquinoline quinone extends Caenorhabditis elegans ’ longevity through the insulin/IGF1 signaling pathway-mediated activation of autophagy
inferred← citeshttps://doi.org/10.1039/d3cc03753copenalex-snapshot
CuBr-mediated synthesis of 1,4-naphthoquinones via ring expansion of 2-aryl-1,3-indandiones
inferred← citeshttps://doi.org/10.1042/bcj20240447openalex-snapshot
Identification of inhibitors of human ChaC1, a cytoplasmic glutathione degrading enzyme through high throughput screens in yeast
inferred← citeshttps://doi.org/10.1055/s-0031-1280092openalex-snapshot
Structure/Antileishmanial Activity Relationship Study of Naphthoquinones and Dependency of the Mode of Action on the Substitution Patterns
inferred← citeshttps://doi.org/10.1074/jbc.m110.200501openalex-snapshot
Reduction of Clofazimine by Mycobacterial Type 2 NADH:Quinone Oxidoreductase
inferred← citeshttps://doi.org/10.1074/jbc.m112.344903openalex-snapshot
Borrelia burgdorferi, a Pathogen That Lacks Iron, Encodes Manganese-dependent Superoxide Dismutase Essential for Resistance to Streptonigrin
inferred← citeshttps://doi.org/10.1074/jbc.m113.486522openalex-snapshot
Naphthoquinone-mediated Inhibition of Lysine Acetyltransferase KAT3B/p300, Basis for Non-toxic Inhibitor Synthesis
inferred← citeshttps://doi.org/10.1074/jbc.m601595200openalex-snapshot
Plumbagin (5-Hydroxy-2-methyl-1,4-naphthoquinone) Suppresses NF-κB Activation and NF-κB-regulated Gene Products Through Modulation of p65 and IκBα Kinase Activation, Leading to Potentiation of Apoptosis Induced by Cytokine and Chemotherapeutic Agents
inferred← citeshttps://doi.org/10.1074/jbc.m607646200openalex-snapshot
Micromolar Intracellular Hydrogen Peroxide Disrupts Metabolism by Damaging Iron-Sulfur Enzymes
inferred← citeshttps://doi.org/10.1074/jbc.m710264200openalex-snapshot
Juglone Inactivates Cysteine-rich Proteins Required for Progression through Mitosis
inferred← citeshttps://doi.org/10.1080/00405000.2016.1186340openalex-snapshot
Efficient mothproofing of wool through natural dyeing with walnut hull and henna against Dermestes maculatus
inferred← citeshttps://doi.org/10.1080/03602530701690366openalex-snapshot
Drug-Metabolizing Enzymes in the Skin of Man, Rat, and Pig
inferred← citeshttps://doi.org/10.1080/07391102.2020.1852116openalex-snapshot
Synthesis, characterization, molecular docking and anticancer studies of fluoroaniline derivatives of hydroxybenzoquinone and hydroxynaphthoquinone
inferred← citeshttps://doi.org/10.1080/09593332808618873openalex-snapshot
The Influence of Water Quality on the Toxicity and Degradation of Juglone (5-Hydroxy 1,4-Naphthoquinone)
inferred← citeshttps://doi.org/10.1080/10286020.2011.633515openalex-snapshot
Reviews on 1,4-naphthoquinones fromDiospyrosL.
inferred← citeshttps://doi.org/10.1080/10406638.2011.581261openalex-snapshot
Synthesis and Anti-Proliferative Activity of Novel Quinolin-8-ol Derivatives
inferred← citeshttps://doi.org/10.1080/10426507.2012.727515openalex-snapshot
Synthesis and Antibacterial and Antifungal Properties of Novel S-, N-, N,S-, and S,O-Substituted 1,4-Naphthoquinone Derivatives
inferred← citeshttps://doi.org/10.1080/10426507.2013.829830openalex-snapshot
Mini Review of Sulfur Heterocyclization from π-Electron Deficient Quinones via Charge-Transfer Interaction
inferred← citeshttps://doi.org/10.1080/10715762.2022.2155518openalex-snapshot
Lactobacillus brevis MTCC 1750 enhances oxidative stress resistance and lifespan extension with improved physiological and functional capacity in Caenorhabditis elegans via the DAF-16 pathway
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