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Inhibition of Thyroid Hormone Sulfotransferase Activity by Brominated Flame Retardants and Halogenated Phenolics

https://doi.org/10.1021/tx400342k
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Assessing energy functions for flexible docking
inferredcites →https://doi.org/10.1002/jcc.10306openalex-snapshot
Detailed analysis of grid‐based molecular docking: A case study of CDOCKER—A CHARMm‐based MD docking algorithm
inferredcites →https://doi.org/10.1002/mnfr.200700104openalex-snapshot
Biotransformation of brominated flame retardants into potentially endocrine‐disrupting metabolites, with special attention to 2,2′,4,4′‐tetrabromodiphenyl ether (BDE‐47)
inferredcites →https://doi.org/10.1006/bbrc.1999.1419openalex-snapshot
Sulfation of Iodothyronines by Recombinant Human Liver Steroid Sulfotransferases
inferredcites →https://doi.org/10.1006/toxs.1998.2504openalex-snapshot
In VitroInhibition of Thyroid Hormone Sulfation by Polychlorobiphenylols: Isozyme Specificity and Inhibition Kinetics
inferredcites →https://doi.org/10.1007/s002040000208openalex-snapshot
Effects of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) on thyroid hormone and vitamin A levels in rats and mice
inferredcites →https://doi.org/10.1016/0009-2797(94)90071-xopenalex-snapshot
Role of sulfation in thyroid hormone metabolism
inferredcites →https://doi.org/10.1016/j.mce.2011.09.005openalex-snapshot
Thyroid effects of endocrine disrupting chemicals
inferredcites →https://doi.org/10.1016/j.scitotenv.2012.12.017openalex-snapshot
Associations between brominated flame retardants in house dust and hormone levels in men
inferredcites →https://doi.org/10.1016/j.taap.2006.02.008openalex-snapshot
Polybrominated diphenyl ether (PBDE)-induced alterations in vitamin A and thyroid hormone concentrations in the rat during lactation and early postnatal development
inferredcites →https://doi.org/10.1016/j.taap.2008.06.014openalex-snapshot
Biosensor discovery of thyroxine transport disrupting chemicals
inferredcites →https://doi.org/10.1016/j.tox.2004.06.041openalex-snapshot
Endocrine active compounds affect thyrotropin and thyroid hormone levels in serum as well as endpoints of thyroid hormone action in liver, heart and kidney
inferredcites →https://doi.org/10.1016/s0009-2797(97)00139-7openalex-snapshot
Characterization of thyroid hormone sulfotransferases
inferredcites →https://doi.org/10.1016/s0009-2797(97)00140-3openalex-snapshot
Inhibition of thyroid hormone sulfation by hydroxylated metabolites of polychlorinated biphenyls
inferredcites →https://doi.org/10.1016/s0021-9258(18)67288-6openalex-snapshot
Inhibition of rat liver iodothyronine deiodinase. Interaction of aurones with the iodothyronine ligand-binding site.
inferredcites →https://doi.org/10.1021/ci800081sopenalex-snapshot
Fully Automated Molecular Mechanics Based Induced Fit Protein−Ligand Docking Method
inferredcites →https://doi.org/10.1021/tx9800046openalex-snapshot
In Vitro Inhibition of Thyroid Hormone Sulfation by Hydroxylated Metabolites of Halogenated Aromatic Hydrocarbons
inferredcites →https://doi.org/10.1074/jbc.m207246200openalex-snapshot
Structure of a Human Carcinogen-converting Enzyme, SULT1A1
inferredcites →https://doi.org/10.1074/jbc.m508289200openalex-snapshot
The Structure of Human SULT1A1 Crystallized with Estradiol
inferredcites →https://doi.org/10.1089/thy.2005.15.943openalex-snapshot
Alternate Pathways of Thyroid Hormone Metabolism
inferredcites →https://doi.org/10.1093/toxsci/56.1.95openalex-snapshot
Potent Competitive Interactions of Some Brominated Flame Retardants and Related Compounds with Human Transthyretin in Vitro
inferredcites →https://doi.org/10.1093/toxsci/kfj187openalex-snapshot
In Vitro Profiling of the Endocrine-Disrupting Potency of Brominated Flame Retardants
inferredcites →https://doi.org/10.1093/toxsci/kfn230openalex-snapshot
Effects of Perinatal PBDE Exposure on Hepatic Phase I, Phase II, Phase III, and Deiodinase 1 Gene Expression Involved in Thyroid Hormone Metabolism in Male Rat Pups
inferredcites →https://doi.org/10.1093/toxsci/kfr117openalex-snapshot
Halogenated Phenolic Contaminants Inhibit the In Vitro Activity of the Thyroid-Regulating Deiodinases in Human Liver
inferredcites →https://doi.org/10.1111/j.1365-3083.2009.02277.xopenalex-snapshot
Modelling of Bet v 1 Binding to Lipids
inferredcites →https://doi.org/10.1124/dmd.104.000273openalex-snapshot
TRICLOSAN AS A SUBSTRATE AND INHIBITOR OF 3′-PHOSPHOADENOSINE 5′-PHOSPHOSULFATE-SULFOTRANSFERASE AND UDP-GLUCURONOSYL TRANSFERASE IN HUMAN LIVER FRACTIONS
inferredcites →https://doi.org/10.1124/dmd.109.028399openalex-snapshot
Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT “Pie”
inferredcites →https://doi.org/10.1126/science.116.3013.329openalex-snapshot
On the Evaluation of the Constants V m and K M in Enzyme Reactions
inferredcites →https://doi.org/10.1137/1.9780898718362openalex-snapshot
The Analysis of Means
inferredcites →https://doi.org/10.1152/physrev.2001.81.3.1097openalex-snapshot
Physiological and Molecular Basis of Thyroid Hormone Action
inferredcites →https://doi.org/10.1186/1476-069x-11-s1-s10openalex-snapshot
Thyroid hormone metabolism and environmental chemical exposure
inferredcites →https://doi.org/10.1210/edrv.23.1.0455openalex-snapshot
Biochemistry, Cellular and Molecular Biology, and Physiological Roles of the Iodothyronine Selenodeiodinases
inferredcites →https://doi.org/10.1210/en.135.5.2086openalex-snapshot
Sulfation after deiodination of 3,5,3'-triiodothyronine in rat cultured astrocytes
inferredcites →https://doi.org/10.1210/en.141.5.1897openalex-snapshot
Potent Inhibition of Estrogen Sulfotransferase by Hydroxylated PCB Metabolites: A Novel Pathway Explaining the Estrogenic Activity of PCBs
inferredcites →https://doi.org/10.1210/er.2011-1050openalex-snapshot
Hormones and Endocrine-Disrupting Chemicals: Low-Dose Effects and Nonmonotonic Dose Responses
inferredcites →https://doi.org/10.1210/jc.75.1.189openalex-snapshot
A radioimmunoassay for measurement of 3,5,3'-triiodothyronine sulfate: studies in thyroidal and nonthyroidal diseases, pregnancy, and neonatal life
inferredcites →https://doi.org/10.1210/jc.84.7.2577openalex-snapshot
Sulfation of Thyroid Hormone by Estrogen Sulfotransferase
inferredcites →https://doi.org/10.1210/jcem.84.4.5590openalex-snapshot
Characterization of Human Iodothyronine Sulfotransferases1
inferredcites →https://doi.org/10.1248/jhs.54.607openalex-snapshot
Affinity for Thyroid Hormone and Estrogen Receptors of Hydroxylated Polybrominated Diphenyl Ethers
inferredcites →https://doi.org/10.1289/ehp.0900753openalex-snapshot
Nuclear Hormone Receptor Activity of Polybrominated Diphenyl Ethers and Their Hydroxylated and Methoxylated Metabolites in Transactivation Assays Using Chinese Hamster Ovary Cells
inferredcites →https://doi.org/10.1289/ehp.1001905openalex-snapshot
Polybrominated Diphenyl Ether (PBDE) Flame Retardants and Thyroid Hormone during Pregnancy
inferredcites →https://doi.org/10.1289/ehp.1003235openalex-snapshot
Associations between Polybrominated Diphenyl Ether (PBDE) Flame Retardants, Phenolic Metabolites, and Thyroid Hormones during Pregnancy
inferredcites →https://doi.org/10.1289/ehp.10713openalex-snapshot
Polybrominated Diphenyl Ethers (PBDEs) and Bioaccumulative Hydroxylated PBDE Metabolites in Young Humans from Managua, Nicaragua
inferredcites →https://doi.org/10.1289/ehp.11660openalex-snapshot
Hydroxylated Metabolites of Polybrominated Diphenyl Ethers in Human Blood Samples from the United States
inferredcites →https://doi.org/10.1289/ehp.11707openalex-snapshot
Hormone Disruption by PBDEs in Adult Male Sport Fish Consumers
inferredcites →https://doi.org/10.1289/ehp.6056openalex-snapshot
Crystallographic analysis of a hydroxylated polychlorinated biphenyl (OH-PCB) bound to the catalytic estrogen binding site of human estrogen sulfotransferase.
inferredcites →https://doi.org/10.1517/17425255.2012.677027openalex-snapshot
Crystal structures of human sulfotransferases: insights into the mechanisms of action and substrate selectivity
inferredcites →https://doi.org/10.2174/138920006774832596openalex-snapshot
Inhibition of Sulfotransferases by Xenobiotics
inferredcites →https://doi.org/10.2174/138920008783571819openalex-snapshot
Structure, Function and Polymorphism of Human Cytosolic Sulfotransferases

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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A 2024 inventory of test methods relevant to thyroid hormone system disruption for human health and environmental regulatory hazard assessment
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Halogen‐Bonding Interactions of Polybrominated Diphenyl Ethers and Thyroid Hormone Derivatives: A Potential Mechanism for the Inhibition of Iodothyronine Deiodinase
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Derivation of a no‐significant‐risk‐level for tetrabromobisphenol A based on a threshold non‐mutagenic cancer mode of action
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Development of an analytical method to quantify PBDEs, OH-BDEs, HBCDs, 2,4,6-TBP, EH-TBB, and BEH-TEBP in human serum
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Thyroid hormone system disrupting chemicals
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The genome of the euryhaline rotifer Brachionus paranguensis: Potential use in molecular ecotoxicology
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Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2018.01.081openalex-snapshot
Increased coiling frequency linked to apoptosis in the brain and altered thyroid signaling in zebrafish embryos (Danio rerio) exposed to the PBDE metabolite 6-OH-BDE-47
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Occurrence, endocrine-related bioeffects and fate of bisphenol A chemical degradation intermediates and impurities: A review
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Investigating the molecular mechanism of hydroxylated bromdiphenyl ethers to inhibit the thyroid hormone sulfotransferase SULT1A1
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Hepatic demethylation of methoxy-bromodiphenyl ethers and conjugation of the resulting hydroxy-bromodiphenyl ethers in a marine fish, the red snapper, Lutjanus campechanus, and a freshwater fish, the channel catfish, Ictalurus punctatus
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2022.136920openalex-snapshot
Thyroid hormone activities of neutral and anionic hydroxylated polybrominated diphenyl ethers to thyroid receptor β: A molecular dynamics study
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Fathoming the link between anthropogenic chemical contamination and thyroid cancer
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In silico study for inhibiting thyroid hormone sulfotransferase activity by halogenated phenolic chemicals
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Associations of birth outcomes with maternal polybrominated diphenyl ethers and thyroid hormones during pregnancy
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Concentrations of polybrominated diphenyl ethers (PBDEs) and 2,4,6-tribromophenol in human placental tissues
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Polybrominated diphenyl ether (PBDE) exposures and thyroid hormones in children at age 3 years
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Biotransformation of 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine (TTBP-TAZ) can contribute to high levels of 2,4,6-tribromophenol (2,4,6-TBP) in humans
inferred← citeshttps://doi.org/10.1016/j.envpol.2015.04.015openalex-snapshot
Organobromine compound profiling in human adipose: Assessment of sources of bromophenol
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Plasma polybrominated diphenyl ethers, urinary heavy metals and the risk of thyroid cancer: A case-control study in China
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A family-based risk assessment of PBDE exposure using a multi-pathway approach: Integrating diet, dust, air and serum measurements
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Associations between persistent organic pollutants and thyroid-related hormones and homeostasis parameters in middle-aged to older men and postmenopausal women: The HCHS/SOL
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Halogenated flame retardants, thyroid function biomarkers, attention-deficit/hyperactivity disorder-related traits and neurodevelopment in children: Recent evidence from a Canadian prospective birth cohort study
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Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems
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Placental and lactational transfer of decabromodiphenyl ether and 2,2′,4,4′-tetrabromodiphenyl ether in dam-offspring pairs of Sprague-Dawley rats
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In silico profiling of endocrine-disrupting potential of bisphenol analogues and their halogenated transformation products
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Occurrence and profiles of halogenated phenols, polybrominated diphenyl ethers and hydroxylated polybrominated diphenyl ethers in the effluents of waste water treatment plants around Huang-Bo Sea, North China
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Evaluation of the bioaccumulation potential of selected alternative brominated flame retardants in marine fish using in vitro metabolic transformation rates
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Endocrine disrupting chemical mixture exposure and risk of papillary thyroid cancer in U.S. military personnel: A nested case-control study
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Eliminating Thiamphenicol with abundant H* and •OH generated on a morphologically transformed Co3O4 cathode in electric field
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Disruption of Type 2 Iodothyronine Deiodinase Activity in Cultured Human Glial Cells by Polybrominated Diphenyl Ethers
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In Silico Investigation of the Thyroid Hormone Activity of Hydroxylated Polybrominated Diphenyl Ethers
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Formation of Halogenated Polyaromatic Compounds by Laccase Catalyzed Transformation of Halophenols
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Inhaling Benzene, Toluene, Nitrogen Dioxide, and Sulfur Dioxide, Disrupts Thyroid Function in Captive American Kestrels (Falco sparverius)
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Impacts of Unregulated Novel Brominated Flame Retardants on Human Liver Thyroid Deiodination and Sulfotransferation
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Associations between Exposure to Persistent Organic Pollutants and Thyroid Function in a Case-Control Study of East China
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Persistent Organic Pollutants in Human Breast Milk and Associations with Maternal Thyroid Hormone Homeostasis
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Sustainable B12-Dependent Dehalogenation of Organohalides in E. coli
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Primary Role of Cytochrome P450 2B6 in the Oxidative Metabolism of 2,2′,4,4′,6-Pentabromodiphenyl Ether (BDE-100) to Hydroxylated BDEs
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Cytosolic sulfotransferases in endocrine disruption
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In Silico Prediction of Human Sulfotransferase 1E1 Activity Guided by Pharmacophores from Molecular Dynamics Simulations
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A predictive data-driven framework for endocrine prioritization: a triazole fungicide case study
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Distribution of polybrominated diphenyl ethers (PBDEs) in placental tissues of maternal and fetal origin in exposed Wistar rats and associations with thyroid hormone levels
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Inhibition of the Human ABC Efflux Transporters P-gp and BCRP by the BDE-47 Hydroxylated Metabolite 6-OH-BDE-47: Considerations for Human Exposure
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Do flame retardant chemicals increase the risk for thyroid dysregulation and cancer?
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Prenatal Exposures to Multiple Thyroid Hormone Disruptors: Effects on Glucose and Lipid Metabolism
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Human Excretion of Polybrominated Diphenyl Ether Flame Retardants: Blood, Urine, and Sweat Study
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Systematic review of prenatal exposure to endocrine disrupting chemicals and autism spectrum disorder in offspring
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Association of Polybrominated Diphenyl Ethers (PBDEs) and Polychlorinated Biphenyls (PCBs) with Hyperthyroidism in Domestic Felines, Sentinels for Thyroid Hormone Disruption
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PBDE flame retardants, thyroid disease, and menopausal status in U.S. women
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Brominated flame retardants in placental tissues: associations with infant sex and thyroid hormone endpoints
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Associations between prenatal maternal exposure to per- and polyfluoroalkyl substances (PFAS) and polybrominated diphenyl ethers (PBDEs) and birth outcomes among pregnant women in San Francisco
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Iodotyrosine Deiodinase, a Novel Target of Environmental Halogenated Chemicals for Disruption of the Thyroid Hormone System in Mammals
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Phenol and Phthalate Effects on Thyroid Hormone Levels during Pregnancy: Relying on In Vitro Assays and Adverse Outcome Pathways to Inform an Epidemiological Analysis
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Lactational Exposure to Polybrominated Diphenyl Ethers and Its Relation to Early Childhood Anthropometric Measurements
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Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches
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Supplemental Material for NTP Research Report on Biological Activity of Bisphenol A (BPA) Structural Analogues and Functional Alternatives. NTP RR 4
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NTP Research Report on Biological Activity of Bisphenol A (BPA) Structural Analogues and Functional Alternatives
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Endocrine disruptors: General characteristics, chemical nature and mechanisms of action. A review.
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Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food
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W-Compound can be used as a Biomarker for Fetal Thyroid Function and a Potential Tool for Screening Congenital Hypothyroidism
inferred← citeshttps://doi.org/10.3389/fcell.2023.1162015openalex-snapshot
Reproductive toxicity of combined effects of endocrine disruptors on human reproduction
inferred← citeshttps://doi.org/10.3389/fendo.2021.814373openalex-snapshot
The Environmental Pollutant Bromophenols Interfere With Sulfotransferase That Mediates Endocrine Hormones
inferred← citeshttps://doi.org/10.3389/fendo.2022.883827openalex-snapshot
The Influence of Triclosan on the Thyroid Hormone System in Humans - A Systematic Review
inferred← citeshttps://doi.org/10.3390/ijerph14030268openalex-snapshot
Correlation between Prenatal Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Infant Birth Outcomes: A Meta-Analysis and an Experimental Study
inferred← citeshttps://doi.org/10.3390/ijerph15081735openalex-snapshot
Nutritional and Environmental Factors in Thyroid Carcinogenesis
inferred← citeshttps://doi.org/10.3390/molecules25061328openalex-snapshot
A Halogen Bonding Perspective on Iodothyronine Deiodinase Activity
inferred← citeshttps://doi.org/10.35371/aoem.2019.31.e22openalex-snapshot
Relationship between triclosan exposure and thyroid hormones: the Second Korean National Environmental Health Survey (2012–2014)
inferred← citeshttps://doi.org/10.70675/be87be4dzb625z47a9za246z0a9afe69a223openalex-snapshot
Prenatal exposure to phenols and phthalates, child neurodevelopment and the role of the thyroid hormones
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