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Antibacterial Activity of Sulfamethoxazole Transformation Products (TPs): General Relevance for Sulfonamide TPs Modified at the para Position
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Multiple computer-automated structure evaluation study of aquatic toxicity. III. Vibrio fischeri
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Mode of action and quantitative structure–activity relationship of sulfonamides in biological systems of different complexity (enzymes, bacteria, rat, and human)
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Biodegradation of sulfamethoxazole by individual and mixed bacteria
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The effect of ozone on the biodegradation of 17α-ethinylestradiol and sulfamethoxazole by mixed bacterial cultures
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Photodegradation of sulfonamides and their N 4-acetylated metabolites in water by simulated sunlight irradiation: kinetics and identification of photoproducts
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Antibiotics in the aquatic environment – A review – Part I
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Influence of pH on the sonolysis of ciprofloxacin: Biodegradability, ecotoxicity and antibiotic activity of its degradation products
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Photodegradation of sulfamethoxazole in various aqueous media: Persistence, toxicity and photoproducts assessment
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Tetracycline photolysis in natural waters: Loss of antibacterial activity
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Aerobic biodegradation of the sulfonamide antibiotic sulfamethoxazole by activated sludge applied as co-substrate and sole carbon and nitrogen source
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Toxicity testing with luminescent bacteria – Characterization of an automated method for the combined assessment of acute and chronic effects
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Identification and dynamic modeling of biomarkers for bacterial uptake and effect of sulfonamide antimicrobials
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The occurrence of antibiotics in an urban watershed: From wastewater to drinking water
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Evidence for the microbially mediated abiotic formation of reversible and non-reversible sulfamethoxazole transformation products during denitrification
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Comparative QSAR of the sulfonamide function
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Synthesis and reactions of nitroso sulphamethoxazole with biological nucleophiles: Implications for immune mediated toxicity
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Photochemical Fate of Sulfa Drugs in the Aquatic Environment: Sulfa Drugs Containing Five-Membered Heterocyclic Groups
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Recent Advances in Environmental Risk Assessment of Transformation Products
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Predictive Environmental Risk Assessment of Chemical Mixtures: A Conceptual Framework
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Direct Photolysis of Human Metabolites of the Antibiotic Sulfamethoxazole: Evidence for Abiotic Back-Transformation
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Oxidation of Antibacterial Compounds by Ozone and Hydroxyl Radical: Elimination of Biological Activity during Aqueous Ozonation Processes
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Studies in Chemotherapy. VII. A Theory of the Relation of Structure to Activity of Sulfanilamide Type Compounds1
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In vitroantimicrobial activity of hydroxy and N4‐acetyl sulphonamide metabolites
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Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase
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Pharmaceuticals suppress algal growth and microbial respiration and alter bacterial communities in stream biofilms
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Fate and impacts of pharmaceuticals and personal care products after repeated applications of organic waste products in long-term field experiments
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Degradation kinetics and mechanism of sulfadiazine and sulfamethoxazole in an agricultural soil system with manure application
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2018.03.232openalex-snapshot
Contribution of biotic and abiotic factors in the natural attenuation of sulfamethoxazole: A path analysis approach
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2018.06.122openalex-snapshot
Transformation products of amoxicillin and ampicillin after photolysis in aqueous matrices: Identification and kinetics
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2021.150023openalex-snapshot
Fate of sulfamethoxazole in compost, manure and soil amended with previously stored organic wastes
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2021.151702openalex-snapshot
Delineating the impact of COVID-19 on antimicrobial resistance: An Indian perspective
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2021.152567openalex-snapshot
Removal efficiency for emerging contaminants in a WWTP from Madrid (Spain) after secondary and tertiary treatment and environmental impact on the Manzanares River
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2022.154744openalex-snapshot
Transformation products of sulfonamides in aquatic systems: Lessons learned from available environmental fate and behaviour data
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2022.159156openalex-snapshot
Assessing the fate of antibiotics and agrochemicals during anaerobic digestion of animal manure
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.170332openalex-snapshot
Autotrophic degradation of sulfamethoxazole using sulfate-reducing biocathode in microbial photo-electrolysis system
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.171027openalex-snapshot
How data on transformation products can support the redesign of sulfonamides towards better biodegradability in the environment
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2025.180543openalex-snapshot
Antibiotics in the aquatic environment. A deep voyage across chemical occurrence data, socio-economic relationships and international policies on antimicrobial consumption and resistance within 2014–2024
inferred← citeshttps://doi.org/10.1016/j.seppur.2023.123120openalex-snapshot
Understanding the electro-cocatalytic peroxymonosulfate-based systems with BDD versus DSA anodes: Radical versus nonradical dominated degradation mechanisms
inferred← citeshttps://doi.org/10.1016/j.soilbio.2020.107924openalex-snapshot
Microbial responses to selected pharmaceuticals in agricultural soils: Microcosm study on the roles of soil, treatment and time
inferred← citeshttps://doi.org/10.1016/j.susmat.2026.e02085openalex-snapshot
Valorization of size-fractionated black mass from spent lithium-ion batteries for catalytic peroxymonosulfate activation
inferred← citeshttps://doi.org/10.1016/j.talanta.2016.05.061openalex-snapshot
Multiresidue trace analysis of pharmaceuticals, their human metabolites and transformation products by fully automated on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.talanta.2021.122953openalex-snapshot
Coupling of spectrometric, chromatographic, and chemometric analysis in the investigation of the photodegradation of sulfamethoxazole
inferred← citeshttps://doi.org/10.1016/j.teac.2021.e00118openalex-snapshot
Occurrence of pharmaceutical metabolites and transformation products in the aquatic environment of the Mediterranean area
inferred← citeshttps://doi.org/10.1016/j.tet.2018.05.024openalex-snapshot
N-(acridin-9-yl)arenesulfonamides: Synthesis, quantum chemical studies and crystal structure analysis to establish the tautomeric preferences
inferred← citeshttps://doi.org/10.1016/j.watres.2015.11.026openalex-snapshot
Comment on “Thermo activated persulfate oxidation of antibiotic sulfamethoxazole and structurally related compounds” by Yuefei Ji et al. [Water Res. 87 (2015) 1–9]
inferred← citeshttps://doi.org/10.1016/j.watres.2016.02.022openalex-snapshot
Enhanced sulfamethoxazole degradation through ammonia oxidizing bacteria co-metabolism and fate of transformation products
inferred← citeshttps://doi.org/10.1016/j.watres.2016.06.042openalex-snapshot
A non-target approach to identify disinfection byproducts of structurally similar sulfonamide antibiotics
inferred← citeshttps://doi.org/10.1016/j.watres.2017.03.054openalex-snapshot
Degradation of sulfamethoxazole by UV, UV/H2O2 and UV/persulfate (PDS): Formation of oxidation products and effect of bicarbonate
inferred← citeshttps://doi.org/10.1016/j.watres.2018.08.034openalex-snapshot
Distribution and fate of pharmaceuticals and their metabolite conjugates in a municipal wastewater treatment plant
inferred← citeshttps://doi.org/10.1016/j.watres.2018.09.037openalex-snapshot
Non-activated peroxymonosulfate oxidation of sulfonamide antibiotics in water: Kinetics, mechanisms, and implications for water treatment
inferred← citeshttps://doi.org/10.1016/j.watres.2019.05.031openalex-snapshot
Cometabolic biotransformation and microbial-mediated abiotic transformation of sulfonamides by three ammonia oxidizers
inferred← citeshttps://doi.org/10.1016/j.watres.2020.116629openalex-snapshot
Study of free nitrous acid (FNA)-based elimination of sulfamethoxazole: Kinetics, transformation pathways, and toxicity assessment
inferred← citeshttps://doi.org/10.1016/j.watres.2021.117463openalex-snapshot
Abiotic transformation and ecotoxicity change of sulfonamide antibiotics in environmental and water treatment processes: A critical review
inferred← citeshttps://doi.org/10.1016/j.watres.2021.117616openalex-snapshot
Redox-dependent biotransformation of sulfonamide antibiotics exceeds sorption and mineralization: Evidence from incubation of sediments from a reclaimed water-affected river
inferred← citeshttps://doi.org/10.1016/j.watres.2023.120753openalex-snapshot
Comprehensive assessment of toxicity and environmental risk associated with sulfamethoxazole biodegradation in sulfur-mediated biological wastewater treatment
inferred← citeshttps://doi.org/10.1016/j.watres.2024.121350openalex-snapshot
Fate of sulfamethoxazole in wetland sediment under controlled redox conditions
inferred← citeshttps://doi.org/10.1016/j.watres.2026.126860openalex-snapshot
Reply to “Comment on ‘unveiling the environmental fate and risks of non-heterocyclic sulfacetamide: From a novel degradation mechanism to microecological effects [Water Research 294 (2026) 125520]: Towards practical implementation and risk mitigation’”
inferred← citeshttps://doi.org/10.1021/acs.est.2c05001openalex-snapshot
Sulfamethoxazole Enhances Specific Enzymatic Activities under Aerobic Heterotrophic Conditions: A Metaproteomic Approach
inferred← citeshttps://doi.org/10.1021/acs.est.3c03698openalex-snapshot
Degradation of Sulfamethoxazole by Manganese(IV) Oxide in the Presence of Humic Acid: Role of Stabilized Semiquinone Radicals
inferred← citeshttps://doi.org/10.1021/acs.est.3c05008openalex-snapshot
Suspect and Nontarget Screening Reveal the Underestimated Risks of Antibiotic Transformation Products in Wastewater Treatment Plant Effluents
inferred← citeshttps://doi.org/10.1021/acs.est.5c15195openalex-snapshot
Target and Nontarget Analyses Reveal Similar Dissolved Organic Contaminant Patterns Relative to Quantified Catchment Characteristics along Two German Rivers
inferred← citeshttps://doi.org/10.1021/acs.est.7b06026openalex-snapshot
Bacteria That Make a Meal of Sulfonamide Antibiotics: Blind Spots and Emerging Opportunities
inferred← citeshttps://doi.org/10.1021/acs.est.7b06716openalex-snapshot
Biotransformation of Sulfonamide Antibiotics in Activated Sludge: The Formation of Pterin-Conjugates Leads to Sustained Risk
inferred← citeshttps://doi.org/10.1021/acs.est.9b01131openalex-snapshot
Insights into the Fate and Removal of Antibiotics in Engineered Biological Treatment Systems: A Critical Review
inferred← citeshttps://doi.org/10.1021/acs.est.9b01386openalex-snapshot
The Role of Reactive Nitrogen Species in Sensitized Photolysis of Wastewater-Derived Trace Organic Contaminants
inferred← citeshttps://doi.org/10.1021/acs.jafc.1c02496openalex-snapshot
Accurate Quantification of Sulfonamide Metabolites in Goat Meat: A New Strategy for Minimizing Interaction between Sheep Serum Albumin and Sulfonamide Metabolites
inferred← citeshttps://doi.org/10.1021/acs.joc.2c03053openalex-snapshot
Synthesis of (4-Trifluoromethyl)isoxazoles through a Tandem Trifluoromethyloximation/Cyclization/Elimination Reaction of α,β-Unsaturated Carbonyls
inferred← citeshttps://doi.org/10.1021/acs.joc.4c01312openalex-snapshot
Access to Isoxazoles via Photo-oxygenation of Furan Tethered α-Azidoketones
inferred← citeshttps://doi.org/10.1021/acs.jpca.1c01974openalex-snapshot
Stepwise Microhydration of Isoxazole: Infrared Spectroscopy of Isoxazole-(Water)n≤2 Clusters in Helium Nanodroplets
inferred← citeshttps://doi.org/10.1021/acsabm.0c01402openalex-snapshot
pH-Degradable Polymers as Impermanent Antimicrobial Agents for Environmental Sustainability
inferred← citeshttps://doi.org/10.1021/acsami.2c00755openalex-snapshot
Unexpected Intrinsic Catalytic Function of Porous Boron Nitride Nanorods for Highly Efficient Peroxymonosulfate Activation in Water Treatment
inferred← citeshttps://doi.org/10.1021/acsami.7b10904openalex-snapshot
Significance of a Noble Metal Nanolayer on the UV and Visible Light Photocatalytic Activity of Anatase TiO2 Thin Films Grown from a Scalable PECVD/PVD Approach
inferred← citeshttps://doi.org/10.1021/acsestengg.5c01000openalex-snapshot
Periodate Activation by Contact-Electrification for Organic Pollutant Degradation: Performance and Mechanisms
inferred← citeshttps://doi.org/10.1021/acsestwater.5c00327openalex-snapshot
Exploring the Role of Photolysis in the Aquatic Fate of Antimicrobial Transformation Products: Implications for One Health
inferred← citeshttps://doi.org/10.1021/acsomega.3c02637openalex-snapshot
Degradation of Sulfonamides by UV/Electrochemical Oxidation and the Effects of Treated Effluents on the Bacterial Community in Surface Water
inferred← citeshttps://doi.org/10.1038/s41598-017-16132-8openalex-snapshot
FMNH2-dependent monooxygenases initiate catabolism of sulfonamides in Microbacterium sp. strain BR1 subsisting on sulfonamide antibiotics
inferred← citeshttps://doi.org/10.1038/s41598-021-99618-wopenalex-snapshot
Synthesis of some novel coumarin isoxazol sulfonamide hybrid compounds, 3D-QSAR studies, and antibacterial evaluation
inferred← citeshttps://doi.org/10.1038/s44221-026-00640-xopenalex-snapshot
Neglected positive role of inactivating antibiotic resistance genes in the environment
inferred← citeshttps://doi.org/10.1038/s44221-026-00663-4openalex-snapshot
Antibiotic transformation products exert selective pressure for antimicrobial resistance comparable to parent compounds
inferred← citeshttps://doi.org/10.1039/c7em00100bopenalex-snapshot
Exploring micropollutant biotransformation in three freshwater phytoplankton species
inferred← citeshttps://doi.org/10.1039/c7ra10150copenalex-snapshot
Enhanced sulfamethoxazole degradation in soil by immobilized sulfamethoxazole-degrading microbes on bagasse
inferred← citeshttps://doi.org/10.1039/d0ra05704eopenalex-snapshot
Cooperation of Fe(II) and peroxymonosulfate for enhancement of sulfamethoxazole photodegradation: mechanism study and toxicity elimination
inferred← citeshttps://doi.org/10.1039/d4em00593gopenalex-snapshot
Reversible transformations of sulfamethoxazole and its submoieties by manganese-oxidizing bacteria and biogenic manganese oxides in the presence of humic substances
inferred← citeshttps://doi.org/10.1039/d4ob00878bopenalex-snapshot
Metal-free efficient synthesis of aryl sulfonamides from N -hydroxy sulfonamide and amines
inferred← citeshttps://doi.org/10.1039/d6ra04232eopenalex-snapshot
Titanium-based nanostructures for the photocatalytic degradation of antibiotics
inferred← citeshttps://doi.org/10.1080/00207233.2024.2322896openalex-snapshot
Degradation of antibiotic sulphamethoxazole by application of modified photo-Fenton processes: kinetics, degradation pathways and toxicity
inferred← citeshttps://doi.org/10.1080/10643389.2019.1642831openalex-snapshot
Environmental impact and biological removal processes of pharmaceutically active compounds: The particular case of sulfonamides, anticonvulsants and steroid estrogens
inferred← citeshttps://doi.org/10.1080/17415993.2024.2398574openalex-snapshot
Synthesis of novel isoxazole/dihydroisoxazole tethered β-lactam hybrids via regiospecific 1,3-dipolar cycloaddition methodology on 3-phenylthio-β-lactams
inferred← citeshttps://doi.org/10.1080/17568919.2026.2684542openalex-snapshot
Novel isoxazole-(thio-) and semicarbazone hybrids as promising antibacterial and anticancer agents: synthesis, characterization, biological evaluation, and in silico validation
inferred← citeshttps://doi.org/10.1093/etojnl/vgag207openalex-snapshot
Evaluating bioassays to study the occurrence and fate of antibiotics in the water cycle
inferred← citeshttps://doi.org/10.1093/femsec/fiab140openalex-snapshot
Knowledge gaps in the assessment of antimicrobial resistance in surface waters
inferred← citeshttps://doi.org/10.1093/femsec/fiad125openalex-snapshot
Application of the Aliivibrio fischeri bacterium bioassay for assessing single and mixture effects of antibiotics and copper
inferred← citeshttps://doi.org/10.1111/jam.15267openalex-snapshot
Effects of sulfamethoxazole on aerobic sludge granulation process
inferred← citeshttps://doi.org/10.11606/d.18.2022.tde-03082022-112615openalex-snapshot
Micropoluentes orgânicos emergentes em esgoto sintético tratado por reatores anaeróbios: efeitos tóxicos em invertebrados aquáticos nativos de regiões tropicais
inferred← citeshttps://doi.org/10.1177/23978473221122880openalex-snapshot
Micropollutant transformation and toxicity: Electrochemical ozonation versus biological metabolism
inferred← citeshttps://doi.org/10.1186/s13065-022-00839-5openalex-snapshot
Synthesis of novel isoxazole–carboxamide derivatives as promising agents for melanoma and targeted nano-emulgel conjugate for improved cellular permeability
inferred← citeshttps://doi.org/10.20937/rica.54390openalex-snapshot
Oxidation of sulfonamide micropollutants by versatile peroxidase from Bjerkandera adusta
inferred← citeshttps://doi.org/10.2134/jeq2015.07.0336openalex-snapshot
Antibiotics and Antibiotic Resistance in Agroecosystems: State of the Science
inferred← citeshttps://doi.org/10.2134/jeq2015.07.0393openalex-snapshot
Challenges in the Measurement of Antibiotics and in Evaluating Their Impacts in Agroecosystems: A Critical Review
inferred← citeshttps://doi.org/10.2134/jeq2016.01.0023openalex-snapshot
Antibiotics in Agroecosystems: Introduction to the Special Section
inferred← citeshttps://doi.org/10.2139/ssrn.4907792openalex-snapshot
Degradation of Sulfamethoxazole by Manganese Oxidizing Bacteria and Biogenic Manganese Oxides in the Presence of a Naturally Occurring Redox Mediator
inferred← citeshttps://doi.org/10.2174/1570180819666220819151002openalex-snapshot
Evaluation of Cytotoxic, COX Inhibitory, and Antimicrobial Activities of Novel Isoxazole-carboxamide Derivatives
inferred← citeshttps://doi.org/10.2175/106143015x14338845155101openalex-snapshot
Detection, Occurrence and Fate of Emerging Contaminants in Agricultural Environments
inferred← citeshttps://doi.org/10.3390/applnano7030031openalex-snapshot
Hybrid Nanocatalysts Coupled with Advanced Oxidation and Reduction Processes for Emerging Organic Pollutants, Focusing on Design Evidence, Reactor Configurations, and Sustainability Metrics
inferred← citeshttps://doi.org/10.3390/catal9060500openalex-snapshot
Solar Photocatalytic Degradation of Sulfamethoxazole by TiO2 Modified with Noble Metals
inferred← citeshttps://doi.org/10.3390/ijerph191911859openalex-snapshot
Towards Sustainable Wastewater Treatment: Bioindication as a Technique for Supporting Treatment Efficiency Assessment
inferred← citeshttps://doi.org/10.3390/membranes14110239openalex-snapshot
Pharmaceutical Removal with Photocatalytically Active Nanocomposite Membranes
inferred← citeshttps://doi.org/10.3390/molecules30091907openalex-snapshot
Individual and Simultaneous Photodegradation of Trimethoprim and Sulfamethoxazole Assessed with the Microbial Assay for Risk Assessment
inferred← citeshttps://doi.org/10.4018/979-8-3693-7267-8.ch012openalex-snapshot
Aqua Mediated Multicomponent Synthesis of N, O-Heterocycles and Biological Activity of Fused Isoxazole Derivatives
inferred← citeshttps://doi.org/10.4995/thesis/10251/183052openalex-snapshot
Assessment of novel Advanced Oxidation Processes for the Simultaneous Disinfection and Decontamination of Water
inferred← citeshttps://doi.org/10.5821/dissertation-2117-334954openalex-snapshot
Uptake and metabolization of antibiòtics in crops
inferred← citeshttps://doi.org/10.6084/m9.figshare.20155665openalex-snapshot
Additional file 1 of Synthesis of novel isoxazole–carboxamide derivatives as promising agents for melanoma and targeted nano-emulgel conjugate for improved cellular permeability
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.