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Absorption, Distribution, Metabolism, Excretion, and Toxicity Evaluation in Drug Discovery. 14. Prediction of Human Pregnane X Receptor Activators by Using Naive Bayesian Classification Technique

https://doi.org/10.1021/tx500389q
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ADME Evaluation in Drug Discovery. 7. Prediction of Oral Absorption by Correlation and Classification
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St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
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Identification of New Human Pregnane X Receptor Ligands among Pesticides Using a Stable Reporter Cell System
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In Silico Prediction of Pregnane X Receptor Activators by Machine Learning Approache
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inferredcites →https://doi.org/10.1124/mol.107.038398openalex-snapshot
Human Pregnane X Receptor Antagonists and Agonists Define Molecular Requirements for Different Binding Sites
inferredcites →https://doi.org/10.1124/mol.108.049437openalex-snapshot
Computational Discovery of Novel Low Micromolar Human Pregnane X Receptor Antagonists
inferredcites →https://doi.org/10.1126/science.294.5548.1866openalex-snapshot
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inferredcites →https://doi.org/10.1172/jci3703openalex-snapshot
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Current Industrial Practices in Assessing CYP450 Enzyme Induction: Preclinical and Clinical
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inferredcites →https://doi.org/10.1210/me.14.1.27openalex-snapshot
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inferredcites →https://doi.org/10.1517/17425255.4.6.759openalex-snapshot
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Prediction of Human Drug Metabolizing Enzyme Induction
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Evaluation of 170 Xenobiotics as Transactivators of Human Pregnane X Receptor (hPXR) and Correlation to Known CYP3A4 Drug Interactions
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Recent Developments in Computational Prediction of hERG Blockage

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