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Association of nicotine metabolism and sex with relapse following varenicline and nicotine replacement therapy.

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1 of the 45 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1002/14651858.cd008033.pub3 (notice 2019-10-01).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/14651858.cd005231.pub3openalex-snapshot
Interventions to reduce harm from continued tobacco use
inferredcites →https://doi.org/10.1002/14651858.cd008033.pub3openalex-snapshot
Reduction versus abrupt cessation in smokers who want to quit
inferredcites →https://doi.org/10.1002/14651858.cd009329.pub2openalex-snapshot
Pharmacological interventions for smoking cessation: an overview and network meta-analysis
inferredcites →https://doi.org/10.1006/bbrc.2001.4990openalex-snapshot
Identification of a Single Nucleotide Polymorphism in the TATA Box of the CYP2A6 Gene: Impairment of Its Promoter Activity
inferredcites →https://doi.org/10.1016/j.amepre.2008.04.009openalex-snapshot
A Clinical Practice Guideline for Treating Tobacco Use and Dependence: 2008 Update
inferredcites →https://doi.org/10.1016/j.clpt.2004.02.011openalex-snapshot
Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity*1
inferredcites →https://doi.org/10.1016/j.clpt.2006.01.008openalex-snapshot
Female sex and oral contraceptive use accelerate nicotine metabolism
inferredcites →https://doi.org/10.1016/j.clpt.2006.08.011openalex-snapshot
CYP2A6 genotype and the metabolism and disposition kinetics of nicotine
inferredcites →https://doi.org/10.1016/j.jchromb.2011.09.046openalex-snapshot
Quantification of nicotine, cotinine, trans-3′-hydroxycotinine and varenicline in human plasma by a sensitive and specific UPLC–tandem mass-spectrometry procedure for a clinical study on smoking cessation
inferredcites →https://doi.org/10.1016/j.mayocp.2012.11.013openalex-snapshot
Comparison of the Effectiveness of Varenicline and Combination Nicotine Replacement Therapy for Smoking Cessation in Clinical Practice
inferredcites →https://doi.org/10.1016/j.pbb.2008.10.016openalex-snapshot
Nicotine metabolic rate predicts successful smoking cessation with transdermal nicotine: A validation study
inferredcites →https://doi.org/10.1016/s0022-3565(24)36947-2openalex-snapshot
A Major Role for CYP2A6 in Nicotine C-Oxidation by Human Liver Microsomes
inferredcites →https://doi.org/10.1016/s0022-3565(25)12887-5openalex-snapshot
Characterization of CYP2A6 involved in 3'-hydroxylation of cotinine in human liver microsomes.
inferredcites →https://doi.org/10.1016/s0076-6879(02)57666-7openalex-snapshot
Genotyping human CYP2A6 variants
inferredcites →https://doi.org/10.1016/s2213-2600(14)70294-2openalex-snapshot
Use of the nicotine metabolite ratio as a genetically informed biomarker of response to nicotine patch or varenicline for smoking cessation: a randomised, double-blind placebo-controlled trial
inferredcites →https://doi.org/10.1021/bi00457a031openalex-snapshot
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
inferredcites →https://doi.org/10.1037/a0037692openalex-snapshot
Consideration of sex in clinical trials of transdermal nicotine patch: A systematic review.
inferredcites →https://doi.org/10.1038/clpt.2011.70openalex-snapshot
Impact of Smoking, Smoking Cessation, and Genetic Polymorphisms on CYP1A2 Activity and Inducibility
inferredcites →https://doi.org/10.1056/nejmcp1101512openalex-snapshot
Treating Smokers in the Health Care Setting
inferredcites →https://doi.org/10.1080/01677060802572887openalex-snapshot
Nicotine Dependence Pharmacogenetics: Role of Genetic Variation in Nicotine-Metabolizing Enzymes
inferredcites →https://doi.org/10.1080/14622200600789726openalex-snapshot
Does smoking reduction increase future cessation and decrease disease risk? A qualitative review
inferredcites →https://doi.org/10.1080/14622200802097506openalex-snapshot
Sex differences in long-term smoking cessation rates due to nicotine patch
inferredcites →https://doi.org/10.1093/biomet/81.3.515openalex-snapshot
Proportional Hazards Tests and Diagnostics Based on Weighted Residuals
inferredcites →https://doi.org/10.1093/ntr/ntu335openalex-snapshot
Innovations in Translational Sex and Gender-Sensitive Tobacco Research
inferredcites →https://doi.org/10.1093/ntr/ntv125openalex-snapshot
The Nicotine Metabolite Ratio is Associated With Early Smoking Abstinence Even After Controlling for Factors That Influence the Nicotine Metabolite Ratio
inferredcites →https://doi.org/10.1093/ntr/ntw144openalex-snapshot
Sex Differences in Smoking Cessation Pharmacotherapy Comparative Efficacy: A Network Meta-analysis
inferredcites →https://doi.org/10.1097/01.fpc.0000171517.22258.f1openalex-snapshot
Three haplotypes associated with CYP2A6 phenotypes in Caucasians
inferredcites →https://doi.org/10.1097/cpm.0b013e31828fda4copenalex-snapshot
Smoking Cessation
inferredcites →https://doi.org/10.1097/fpc.0b013e328336eee4openalex-snapshot
ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir coformulated with ritonavir
inferredcites →https://doi.org/10.1111/add.12219openalex-snapshot
Fifty-two-week continuous abstinence rates of smokers being treated with varenicline versus nicotine replacement therapy
inferredcites →https://doi.org/10.1111/add.12895openalex-snapshot
An exploratory short‐term double‐blind randomized trial of varenicline versus nicotine patch for smoking cessation in women
inferredcites →https://doi.org/10.1111/j.1360-0443.1991.tb01879.xopenalex-snapshot
The Fagerström Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire
inferredcites →https://doi.org/10.1124/dmd.107.016568openalex-snapshot
Human CYP2A6 Is Induced by Estrogen via Estrogen Receptor
inferredcites →https://doi.org/10.1136/bmj.b1024openalex-snapshot
Effectiveness and safety of nicotine replacement therapy assisted reduction to stop smoking: systematic review and meta-analysis
inferredcites →https://doi.org/10.1136/tc.2005.011932openalex-snapshot
Health consequences of smoking 1–4 cigarettes per day
inferredcites →https://doi.org/10.1136/thx.2007.090647openalex-snapshot
Varenicline versus transdermal nicotine patch for smoking cessation: results from a randomised open-label trial
inferredcites →https://doi.org/10.1158/1055-9965.epi-05-0723openalex-snapshot
CYP2A6Genotype, Phenotype, and the Use of Nicotine Metabolites as Biomarkers duringAd libitumSmoking
inferredcites →https://doi.org/10.1158/1055-9965.epi-14-0427openalex-snapshot
Known and Novel Sources of Variability in the Nicotine Metabolite Ratio in a Large Sample of Treatment-Seeking Smokers
inferredcites →https://doi.org/10.1176/appi.ajp.2014.13050595openalex-snapshot
Combination Treatment With Varenicline and Bupropion in an Adaptive Smoking Cessation Paradigm
inferredcites →https://doi.org/10.1176/appi.ajp.2014.14081032openalex-snapshot
Smoking Cessation in Men and Women
inferredcites →https://doi.org/10.1176/appi.ajp.2015.14111429openalex-snapshot
Sex Difference in Response to Varenicline for Smoking Cessation
inferredcites →https://doi.org/10.1186/s12889-016-3672-yopenalex-snapshot
Gender difference and effect of pharmacotherapy: findings from a smoking cessation service
inferredcites →https://doi.org/10.2217/14622416.8.10.1385openalex-snapshot
Genetic Variability in CYP2A6 and the Pharmacokinetics of Nicotine
inferredcites →https://doi.org/10.2217/14622416.8.6.623openalex-snapshot
ADME Pathway Approach for Pharmacogenetic Studies of Anti-HIV Therapy
inferredcites →https://doi.org/10.5588/ijtld.11.0183openalex-snapshot
Quitting smoking with varenicline: parallel, randomised efficacy trial in Iran

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4632941openalex-extracted
Association between Nicotine Metabolite Ratio and Smoking Cessation Medications in Chinese Male Smokers - Results of the China National Tobacco Cessation Cohort Study
inferred← citeshttps://doi.org/10.1007/978-3-030-71929-6_5openalex-snapshot
Tobacco Blinders: How Tobacco Control Remained Generic for Far Too Long
inferred← citeshttps://doi.org/10.1016/j.addicn.2023.100076openalex-snapshot
The use of biomarkers to guide precision treatment for tobacco use
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2022.06.007openalex-snapshot
Genetic influences impacting nicotine use and abuse during adolescence: Insights from human and rodent studies
inferred← citeshttps://doi.org/10.1016/j.dadr.2023.100177openalex-snapshot
Sex effects in predictors of smoking abstinence and neuropsychiatric adverse events in the EAGLES trial
inferred← citeshttps://doi.org/10.1016/j.hsr.2024.100186openalex-snapshot
The impact of rate of nicotine metabolism, as measured by the nicotine metabolite ratio (NMR), on smoking behaviours during pregnancy: A scoping review
inferred← citeshttps://doi.org/10.1080/17476348.2024.2429675openalex-snapshot
Is the nicotine metabolite ratio a useful tool to improve the effectiveness, safety, and adherence to quitting smoking? Systematic review of the literature and meta-analysis
inferred← citeshttps://doi.org/10.1111/resp.14702openalex-snapshot
Efficacy of varenicline or bupropion and its association with nicotine metabolite ratio among smokers with COPD
inferred← citeshttps://doi.org/10.1146/annurev-clinpsy-081219-090343openalex-snapshot
Smoking Treatment: A Report Card on Progress and Challenges
inferred← citeshttps://doi.org/10.1158/1940-6207.capr-19-0259openalex-snapshot
The Use of the Nicotine Metabolite Ratio as a Biomarker to Personalize Smoking Cessation Treatment: Current Evidence and Future Directions
inferred← citeshttps://doi.org/10.11606/t.5.2022.tde-03102022-124014openalex-snapshot
Avaliações farmacogenética e da relação de metabólitos da nicotina em pacientes tratados com fármacos antitabagismo
inferred← citeshttps://doi.org/10.3389/fgene.2023.1103966openalex-snapshot
A scoping review of smoking cessation pharmacogenetic studies to advance future research across racial, ethnic, and ancestral populations
inferred← citeshttps://doi.org/10.3389/fphar.2022.900112openalex-snapshot
Evaluation of the nicotine metabolite ratio in smoking patients treated with varenicline and bupropion
inferred← citeshttps://doi.org/10.3390/ijerph17030872openalex-snapshot
Sex- and Gender-Based Analysis in Cannabis Treatment Outcomes: A Systematic Review
inferred← citeshttps://doi.org/10.3390/ijerph18126597openalex-snapshot
Genetic Variants in Smoking-Related Genes in Two Smoking Cessation Programs: A Cross-Sectional Study
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