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Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/j.1460-2075.1995.tb00037.xopenalex-snapshot
Human calcium‐calmodulin dependent protein kinase I: cDNA cloning, domain structure and activation by phosphorylation at threonine‐177 by calcium‐calmodulin dependent protein kinase I kinase.
inferredcites →https://doi.org/10.1002/j.1460-2075.1996.tb01045.xopenalex-snapshot
Mechanism of activation of protein kinase B by insulin and IGF‐1.
inferredcites →https://doi.org/10.1016/0092-8674(95)90534-0openalex-snapshot
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
inferredcites →https://doi.org/10.1016/0306-4522(93)90108-ropenalex-snapshot
Promotion of granule cell survival by high K+ or excitatory amino acid treatment and Ca2+/calmodulin-dependent protein kinase activity
inferredcites →https://doi.org/10.1016/s0092-8674(00)80405-5openalex-snapshot
Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery
inferredcites →https://doi.org/10.1016/s0092-8674(00)81382-3openalex-snapshot
Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL
inferredcites →https://doi.org/10.1016/s0960-9822(06)00122-9openalex-snapshot
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα
inferredcites →https://doi.org/10.1016/s0968-0004(97)01097-9openalex-snapshot
PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond
inferredcites →https://doi.org/10.1038/376599a0openalex-snapshot
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
inferredcites →https://doi.org/10.1073/pnas.86.16.6421openalex-snapshot
Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells.
inferredcites →https://doi.org/10.1073/pnas.88.10.4171openalex-snapshot
Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily.
inferredcites →https://doi.org/10.1073/pnas.93.20.10803openalex-snapshot
Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade.
inferredcites →https://doi.org/10.1074/jbc.270.29.17616openalex-snapshot
Phosphorylation and Activation of Ca2+-Calmodulin-dependent Protein Kinase IV by Ca2+-Calmodulin-dependent Protein Kinase Ia Kinase
inferredcites →https://doi.org/10.1074/jbc.270.33.19320openalex-snapshot
Characterization of a Ca2+/Calmodulin-dependent Protein Kinase Cascade
inferredcites →https://doi.org/10.1074/jbc.270.51.30464openalex-snapshot
Activation of Ca2+/Calmodulin-dependent Protein Kinase (CaM-kinase) IV by CaM-kinase Kinase in Jurkat T Lymphocytes
inferredcites →https://doi.org/10.1074/jbc.271.10.5617openalex-snapshot
Requirements for Calcium and Calmodulin in the Calmodulin Kinase Activation Cascade
inferredcites →https://doi.org/10.1074/jbc.272.26.16073openalex-snapshot
Inhibitory Cross-talk by cAMP Kinase on the Calmodulin-dependent Protein Kinase Cascade
inferredcites →https://doi.org/10.1074/jbc.273.8.4776openalex-snapshot
Differential Regulation by Calcium Reveals Distinct Signaling Requirements for the Activation of Akt and p70S6k
inferredcites →https://doi.org/10.1111/j.1432-1033.1991.tb16305.xopenalex-snapshot
Molecular cloning and characterisation of a novel putative protein‐serine kinase related to the cAMP‐dependent and protein kinase C families
inferredcites →https://doi.org/10.1126/science.275.5300.628openalex-snapshot
Akt Signaling--Linking Membrane Events to Life and Death Decisions
inferredcites →https://doi.org/10.1126/science.275.5300.661openalex-snapshot
Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt
inferredcites →https://doi.org/10.1126/science.277.5325.567openalex-snapshot
Dual Role of Phosphatidylinositol-3,4,5-trisphosphate in the Activation of Protein Kinase B
inferredcites →https://doi.org/10.1126/science.278.5338.687openalex-snapshot
Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt
inferredcites →https://doi.org/10.1126/science.279.5351.710openalex-snapshot
Protein Kinase B Kinases That Mediate Phosphatidylinositol 3,4,5-Trisphosphate-Dependent Activation of Protein Kinase B
inferredcites →https://doi.org/10.1210/me.11.12.1858openalex-snapshot
Interference of BAD (Bcl-xL/Bcl-2-Associated Death Promoter)-Induced Apoptosis in Mammalian Cells by 14-3-3 Isoforms and P11
inferredcites →https://doi.org/10.1523/jneurosci.07-06-01816.1987openalex-snapshot
Naturally-occurring neuron death in the ciliary ganglion of the chick embryo following removal of preganglionic input: evidence for the role of afferents in ganglion cell survival
inferredcites →https://doi.org/10.1523/jneurosci.07-07-02203.1987openalex-snapshot
The role of depolarization in the survival and differentiation of cerebellar granule cells in culture
inferredcites →https://doi.org/10.1523/jneurosci.18-04-01230.1998openalex-snapshot
Calmodulin Is Involved in Membrane Depolarization-Mediated Survival of Motoneurons by Phosphatidylinositol-3 Kinase- and MAPK-Independent Pathways
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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The Character of Intestinal Bacteria Community Structure And Immune Response of Blood Parrot Amphilophus Citrinellus ×Vieja Melanura During LPS Stimulation
inferred← citeshttps://doi.org/10.1002/(sici)1097-0029(19990915)46:6<418::aid-jemt9>3.0.co;2-0openalex-snapshot
Study of calcium signaling in non-excitable cells
inferred← citeshttps://doi.org/10.1002/(sici)1097-4547(19991001)58:1<88::aid-jnr9>3.0.co;2-ropenalex-snapshot
Sending signals from the synapse to the nucleus: Possible roles for CaMK, Ras/ERK, and SAPK pathways in the regulation of synaptic plasticity and neuronal growth
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Hepatocyte growth factor protects cultured rat cerebellar granule neurons from apoptosis via the phosphatidylinositol-3 kinase/Akt pathway
inferred← citeshttps://doi.org/10.1002/0471203076.emm0182openalex-snapshot
Calmodulin‐Dependent Protein Kinases (CaM‐Ks)
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Wnt-1 dependent activation of the survival factor NF-?B in PC12 cells
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In vitro inhibition of antirecoverin immunoglobulin-mediated death of mammalian photoreceptor cells
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Characterization of molecular mechanisms of CaMKKα /1 oligomerization
inferred← citeshttps://doi.org/10.1002/adbi.202200160openalex-snapshot
DNA Methylation Dynamics During Esophageal Epithelial Regeneration Following Repair with Acellular Silk Fibroin Grafts in Rat
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Interaction of pyrin with 14.3.3 in an Isoform‐specific and phosphorylation‐dependent manner regulates its translocation to the nucleus
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The role of calcium‐binding proteins in the control of transcription: structure to function
inferred← citeshttps://doi.org/10.1002/bies.1134openalex-snapshot
14‐3‐3 proteins: key regulators of cell division, signalling and apoptosis
inferred← citeshttps://doi.org/10.1002/bies.20382openalex-snapshot
Why photoreceptors die (and why they don't)
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Molecular machinery and signaling events in apoptosis
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Involvement of P2X 4 and P2Y 12 receptors in ATP‐induced microglial chemotaxis
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Cellular regulation of hepatic bile acid transport in health and cholestasis
inferred← citeshttps://doi.org/10.1002/hep.21298openalex-snapshot
Ischemic preconditioning of the murine liver protects through the Akt kinase pathway
inferred← citeshttps://doi.org/10.1002/hipo.20913openalex-snapshot
A role for the CAMKK pathway in visual object recognition memory
inferred← citeshttps://doi.org/10.1002/ijc.31887openalex-snapshot
Inhibition of Ca2+‐activated chloride channel ANO1 suppresses ovarian cancer through inactivating PI3K/Akt signaling
inferred← citeshttps://doi.org/10.1002/jcb.10086openalex-snapshot
Insulin‐like growth factor‐1 protects peroxynitrite‐induced cell death by preventing cytochromec‐induced caspase‐3 activation
inferred← citeshttps://doi.org/10.1002/jcb.20098openalex-snapshot
Neurotensin negatively modulates Akt activity in neurotensin receptor‐1‐transfected AV12 cells
inferred← citeshttps://doi.org/10.1002/jcb.21657openalex-snapshot
A potential mechanism for short time exposure to hypoxia‐induced DNA synthesis in primary cultured chicken hepatocytes: Correlation between Ca2+/PKC/MAPKs and PI3K/Akt/mTOR
inferred← citeshttps://doi.org/10.1002/jcb.24020openalex-snapshot
CaM kinase control of AKT and LNCaP cell survival
inferred← citeshttps://doi.org/10.1002/jcb.24409openalex-snapshot
Cyclooxygenase‐2 over‐expression inhibits liver apoptosis induced by hyperglycemia
inferred← citeshttps://doi.org/10.1002/jcp.20696openalex-snapshot
Regulation of phosphatidylinositol 3‐kinase (PI3K)/Akt and nuclear factor‐kappa B signaling pathways in dystrophin‐deficient skeletal muscle in response to mechanical stretch
inferred← citeshttps://doi.org/10.1002/jnr.10551openalex-snapshot
Ca2+/calmodulin‐dependent protein kinases II and IV both promote survival but differ in their effects on axon growth in spiral ganglion neurons
inferred← citeshttps://doi.org/10.1002/jnr.20024openalex-snapshot
High K+ and IGF‐1 protect cerebellar granule neurons via distinct signaling pathways
inferred← citeshttps://doi.org/10.1002/jnr.20556openalex-snapshot
PI3K/Akt‐dependent regulation of the transcription factor myocyte enhancer factor‐2 in insulin‐like growth factor‐1‐ and membrane depolarization‐mediated survival of cerebellar granule neurons
inferred← citeshttps://doi.org/10.1002/jnr.21821openalex-snapshot
Lysophosphatidylcholine protects cerebellar granule neurons from apoptotic cell death
inferred← citeshttps://doi.org/10.1002/mus.21255openalex-snapshot
Lean and obese Zucker rats exhibit different patterns of p70s6 kinase regulation in the tibialis anterior muscle in response to high‐force muscle contraction
inferred← citeshttps://doi.org/10.1002/pro.4805openalex-snapshot
14‐3‐3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C‐terminal helices
inferred← citeshttps://doi.org/10.1002/ptr.5764openalex-snapshot
Cognitive Ameliorating Effect ofAcanthopanax koreanumAgainst Scopolamine-Induced Memory Impairment in Mice
inferred← citeshttps://doi.org/10.1006/bbrc.1999.1752openalex-snapshot
Annexin V Counteracts Apoptosis While Inducing Ca2+ Influx in Human Lymphocytic T Cells
inferred← citeshttps://doi.org/10.1006/bbrc.1999.1879openalex-snapshot
Calcium Controls the Transcription of Its Own Transporters and Channels in Developing Neurons
inferred← citeshttps://doi.org/10.1006/excr.1999.4690openalex-snapshot
The Regulation and Activities of the Multifunctional Serine/Threonine Kinase Akt/PKB
inferred← citeshttps://doi.org/10.1006/jmbi.2001.4822openalex-snapshot
Target-induced conformational adaptation of calmodulin revealed by the crystal structure of a complex with nematode Ca2+/calmodulin-dependent kinase kinase peptide
inferred← citeshttps://doi.org/10.1006/nbdi.2000.0325openalex-snapshot
Alterations of Akt1 (PKBα) and p70S6K in Transient Focal Ischemia
inferred← citeshttps://doi.org/10.1006/nbdi.2002.0523openalex-snapshot
Ethanol-Induced Death of Postnatal Hippocampal Neurons
inferred← citeshttps://doi.org/10.1007/978-0-387-74039-3_8openalex-snapshot
EGF Receptor in Breast Cancer Chemoresistance
inferred← citeshttps://doi.org/10.1007/978-1-4020-6191-2_7openalex-snapshot
Physiological Roles Of The Ca2+/Cam-Dependent Protein kinase Cascade In Health and Disease
inferred← citeshttps://doi.org/10.1007/978-1-4020-6426-5_14openalex-snapshot
Regulation of Intracellular Signal Transduction Pathways by Mechanosensitive Ion Channels
inferred← citeshttps://doi.org/10.1007/978-1-4419-9034-1_9openalex-snapshot
Signal Transduction in Bile Formation and Cholestasis
inferred← citeshttps://doi.org/10.1007/978-1-4419-9254-3_9openalex-snapshot
Calcium Channel Mutations and Associated Diseases
inferred← citeshttps://doi.org/10.1007/978-1-4419-9258-1_13openalex-snapshot
ER Calcium and ER Chaperones: New Players in Apoptosis?
inferred← citeshttps://doi.org/10.1007/978-1-4615-0453-5_7openalex-snapshot
Role of the Phosphoinositide 3-Kinase Pathway in Cardiac Hypertrophy
inferred← citeshttps://doi.org/10.1007/978-3-030-12457-1_26openalex-snapshot
Regulation of Multifunctional Calcium/Calmodulin Stimulated Protein Kinases by Molecular Targeting
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French Paradox: A Role for Akt Activation
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Protein phosphorylation networks in motor neuron death
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Calmodulin-Dependent Protein Kinases
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Limiting Apoptosis as a Strategy for CNS Neuroprotection
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Molecular mechanisms of neuronal survival; Roles of kinases in ischemic cell death
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TRPC Channels and Neuron Development, Plasticity, and Activities
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Trace Elements and Neurodegenerative Diseases
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Activity-dependent regulation of the BAX/BCL-2 pathway protects cortical neurons from apoptotic death during early development
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Glibenclamide activates translation in rat pancreatic beta cells through calcium-dependent mTOR, PKA and MEK signalling pathways
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Glucose metabolism-related protein 1 (GMRP1) regulates pancreatic beta cell proliferation and apoptosis via activation of Akt signalling pathway in rats and mice
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Calcium/calmodulin-dependent kinase IV controls glucose-induced Irs2 expression in mouse beta cells via activation of cAMP response element-binding protein
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Cadmium and cellular signaling cascades: interactions between cell death and survival pathways
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Macrophage-epithelial interactions in pulmonary alveoli
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Role of ANO1 in tumors and tumor immunity
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Cyclic Pressure Stimulates DNA Synthesis through the PI3K/Akt Signaling Pathway in Rat Bladder Smooth Muscle Cells
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Phosphorylation of Bad is not essential for PKB-mediated survival signaling in hemopoietic cells
inferred← citeshttps://doi.org/10.1007/s10517-015-2755-6openalex-snapshot
Mdm2-Dependent Regulation of p53 Expression during Long-Term Potentiation
inferred← citeshttps://doi.org/10.1007/s10549-005-4794-6openalex-snapshot
Inhibition of Either Phosphatidylinositol 3-kinase/Akt or the Mitogen/Extracellular-regulated Kinase, MEK/ERK, Signaling Pathways Suppress Growth of Breast Cancer Cell Lines, but MEK/ERK Signaling is Critical for Cell Survival
inferred← citeshttps://doi.org/10.1007/s10549-008-0097-zopenalex-snapshot
Calmodulin modulates Akt activity in human breast cancer cell lines
inferred← citeshttps://doi.org/10.1007/s10571-007-9172-yopenalex-snapshot
Calmodulin Inhibitor-induced Apoptosis was Prevented by Glycogen Synthase Kinase-3 Inhibitors in PC12 Cells
inferred← citeshttps://doi.org/10.1007/s10571-008-9286-xopenalex-snapshot
Enhanced Survival of Melanopsin-expressing Retinal Ganglion Cells After Injury is Associated with the PI3 K/Akt Pathway
inferred← citeshttps://doi.org/10.1007/s11033-025-10813-8openalex-snapshot
CaMKK2 as a therapeutic target to combat metastasis in glioblastoma
inferred← citeshttps://doi.org/10.1007/s11055-013-9707-2openalex-snapshot
Age-Related Development of Calbindin-Immunopositive Neurons in Rat Sympathetic Ganglia
inferred← citeshttps://doi.org/10.1007/s11055-015-0175-8openalex-snapshot
Developmental Characteristics of Neurons in the Intramural Ganglia of the Small Intestine Containing Different Types of Calcium-Binding Proteins
inferred← citeshttps://doi.org/10.1007/s11055-016-0235-8openalex-snapshot
Regulation of S100B Expression in Long-Term Potentiation
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Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation
inferred← citeshttps://doi.org/10.1007/s11302-006-9008-0openalex-snapshot
Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks
inferred← citeshttps://doi.org/10.1007/s12017-019-08563-5openalex-snapshot
Bridging the Gap Between Diabetes and Stroke in Search of High Clinical Relevance Therapeutic Targets
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NMDA Receptor Dependent PGC-1α Up-Regulation Protects the Cortical Neuron Against Oxygen-Glucose Deprivation/Reperfusion Injury
inferred← citeshttps://doi.org/10.1007/s12264-013-1336-9openalex-snapshot
GluN2A versus GluN2B: twins, but quite different
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Molecular Mechanisms of Memory in Males and Females
inferred← citeshttps://doi.org/10.1016/b978-0-12-802810-0.00009-xopenalex-snapshot
Cholesterol and Fat Metabolism in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-822919-4.00011-9openalex-snapshot
Antimicrobial secondary metabolites from Trichoderma spp. as next generation fungicides
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Trichoderma-derived elicitor-like molecules and their role in plant immunity
inferred← citeshttps://doi.org/10.1016/j.abb.2011.06.013openalex-snapshot
Activation of the PI3K/Akt signaling pathway through P2Y2 receptors by extracellular ATP is involved in osteoblastic cell proliferation
inferred← citeshttps://doi.org/10.1016/j.advenzreg.2009.10.016openalex-snapshot
Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells
inferred← citeshttps://doi.org/10.1016/j.anireprosci.2008.02.010openalex-snapshot
Involvement of calcium/calmodulin-dependent protein kinase kinase in meiotic maturation of pig oocytes
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Transcriptome profiling of the Eriocheir sinensis thoracic ganglion under the Spiroplasma eriocheiris challenge
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Calreticulin regulates insulin receptor expression and its downstream PI3 Kinase/Akt signalling pathway
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2011.06.009openalex-snapshot
Thrombin activation of PI3K/PDK1/Akt signaling promotes cyclin D1 upregulation and RPE cell proliferation
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2013.01.021openalex-snapshot
Non-apoptotic roles of Bcl-2 family: The calcium connection
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2025.119982openalex-snapshot
Ion channel expression and function in glioblastoma multiforme (GBM): pathophysiological mechanisms and therapeutic potential
inferred← citeshttps://doi.org/10.1016/j.bbr.2010.12.025openalex-snapshot
NMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways
inferred← citeshttps://doi.org/10.1016/j.bbrc.2004.02.042openalex-snapshot
Impact of brief oxidant stress on primary adult cardiac fibroblasts
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Selective brain responses to acute and chronic low-dose X-ray irradiation in males and females
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Identification of a novel CaMKK substrate
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Phosphorylation and dephosphorylation of Ca2+/calmodulin-dependent protein kinase kinase β at Thr144 in HeLa cells
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Oligomerization of Ca2+/calmodulin-dependent protein kinase kinase
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Specific titin and myomesin domains stimulate myoblast proliferation
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The involvement of AMP-activated protein kinases in the anti-inflammatory effect of nicotine in vivo and in vitro
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Alternating electrical fields to stimulate osteogenic cells and biomimetic calcium phosphate-coated titanium substrates–A combinatorial approach to bone regeneration
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The riddles of Trichoderma induced plant immunity
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T-type Ca2+ channel blocker, KYS05047 induces G1 phase cell cycle arrest by decreasing intracellular Ca2+ levels in human lung adenocarcinoma A549 cells
inferred← citeshttps://doi.org/10.1016/j.brainres.2004.06.035openalex-snapshot
NMDA receptor 2B-selective antagonist ifenprodil-induced apoptosis was prevented by glycogen synthase kinase-3 inhibitors in cultured rat cortical neurons
inferred← citeshttps://doi.org/10.1016/j.brainres.2008.11.095openalex-snapshot
Effects of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils
inferred← citeshttps://doi.org/10.1016/j.brainresrev.2011.04.003openalex-snapshot
Late-life depression and Alzheimer's disease: The glutamatergic system inside of this mirror relationship
inferred← citeshttps://doi.org/10.1016/j.cbpc.2023.109799openalex-snapshot
Pyridaben impaired cell cycle progression through perturbation of calcium homeostasis and PI3K/Akt pathway in zebrafish hepatocytes
inferred← citeshttps://doi.org/10.1016/j.ceca.2017.06.002openalex-snapshot
Role of SOCE architects STIM and Orai proteins in Cell Death
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Mending Fences: Na,K-ATPase signaling via Ca2+ in the maintenance of epithelium integrity
inferred← citeshttps://doi.org/10.1016/j.ceca.2023.102716openalex-snapshot
Too much of a good thing: The case of SOCE in cellular apoptosis
inferred← citeshttps://doi.org/10.1016/j.ceca.2023.102820openalex-snapshot
Transcriptional, biochemical, and immunohistochemical analyses of CaMKKβ/2 splice variants that co-localize with CaMKIV in spermatids
inferred← citeshttps://doi.org/10.1016/j.cell.2011.12.037openalex-snapshot
Interplay between DISC1 and GABA Signaling Regulates Neurogenesis in Mice and Risk for Schizophrenia
inferred← citeshttps://doi.org/10.1016/j.cellsig.2005.09.005openalex-snapshot
P2Y12 receptor signalling towards PKB proceeds through IGF-I receptor cross-talk and requires activation of Src, Pyk2 and Rap1
inferred← citeshttps://doi.org/10.1016/j.cellsig.2006.02.004openalex-snapshot
Clozapine, a neuroleptic agent, inhibits Akt by counteracting Ca2+/calmodulin in PTEN-negative U-87MG human glioblastoma cells
inferred← citeshttps://doi.org/10.1016/j.cellsig.2009.01.003openalex-snapshot
Gastrointestinal growth factors and hormones have divergent effects on Akt activation
inferred← citeshttps://doi.org/10.1016/j.clim.2016.09.009openalex-snapshot
Impaired Akt phosphorylation in B-cells of patients with common variable immunodeficiency
inferred← citeshttps://doi.org/10.1016/j.cmet.2005.05.009openalex-snapshot
Calmodulin-dependent protein kinase kinase-β is an alternative upstream kinase for AMP-activated protein kinase
inferred← citeshttps://doi.org/10.1016/j.cophys.2020.07.016openalex-snapshot
Calcium regulation of T cell metabolism
inferred← citeshttps://doi.org/10.1016/j.cryobiol.2016.05.012openalex-snapshot
IGF1 stabilizes sperm membrane proteins to reduce cryoinjury and maintain post-thaw sperm motility in buffalo (Bubalus bubalis) spermatozoa
inferred← citeshttps://doi.org/10.1016/j.ejmech.2014.07.076openalex-snapshot
Design, synthesis and biological evaluation of novel 1-hydroxyl-3-aminoalkoxy xanthone derivatives as potent anticancer agents
inferred← citeshttps://doi.org/10.1016/j.exphem.2008.02.009openalex-snapshot
A cascade of Ca2+/calmodulin-dependent protein kinases regulates the differentiation and functional activation of murine neutrophils
inferred← citeshttps://doi.org/10.1016/j.expneurol.2011.04.012openalex-snapshot
Ovarian hormones influence corticotropin releasing factor receptor colocalization with delta opioid receptors in CA1 pyramidal cell dendrites
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e28016openalex-snapshot
RETRACTED: Quercetin attenuated ischemic stroke induced neurodegeneration by modulating glutamatergic and synaptic signaling pathways
inferred← citeshttps://doi.org/10.1016/j.humimm.2004.01.002openalex-snapshot
Anti-HLA class I antibody–mediated activation of the PI3K/Akt signaling pathway and induction of Bcl-2 and Bcl-xL expression in endothelial cells
inferred← citeshttps://doi.org/10.1016/j.ijrobp.2004.01.054openalex-snapshot
Targeted therapies for non–small-cell lung cancer: biology, rationale, and preclinical results from a radiation oncology perspective
inferred← citeshttps://doi.org/10.1016/j.isci.2021.102089openalex-snapshot
Rituximab and obinutuzumab differentially hijack the B cell receptor and NOTCH1 signaling pathways
inferred← citeshttps://doi.org/10.1016/j.jhep.2014.06.020openalex-snapshot
Helium preconditioning protects mouse liver against ischemia and reperfusion injury through the PI3K/Akt pathway
inferred← citeshttps://doi.org/10.1016/j.jid.2020.03.936openalex-snapshot
Critical Signaling Events in the Mechanoactivation of Human Mast Cells through p.C492Y-ADGRE2
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2018.04.013openalex-snapshot
Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2025.110059openalex-snapshot
Isosteviol attenuates myocardial ischemia-reperfusion damage by modulating Akt/GSK3β phosphorylation and mitochondrial permeability transition pore opening in female rats
inferred← citeshttps://doi.org/10.1016/j.mcn.2007.05.008openalex-snapshot
CaMKII and CaMKIV mediate distinct prosurvival signaling pathways in response to depolarization in neurons
inferred← citeshttps://doi.org/10.1016/j.mcn.2007.07.014openalex-snapshot
A novel 165-kDa Golgin protein induced by brain ischemia and phosphorylated by Akt protects against apoptosis
inferred← citeshttps://doi.org/10.1016/j.micpath.2019.103789openalex-snapshot
Vibrio vulnificus cytolysin induces inflammatory responses in RAW264.7 macrophages through calcium signaling and causes inflammation in vivo
inferred← citeshttps://doi.org/10.1016/j.nbd.2003.10.013openalex-snapshot
Raising intracellular calcium attenuates neuronal apoptosis triggered by staurosporine or oxygen-glucose deprivation in the presence of glutamate receptor blockade
inferred← citeshttps://doi.org/10.1016/j.neulet.2004.08.029openalex-snapshot
Protective effect of nicotine on tunicamycin-induced apoptosis of PC12h cells
inferred← citeshttps://doi.org/10.1016/j.neulet.2007.07.003openalex-snapshot
Distinct developmental expression of two isoforms of Ca2+/calmodulin-dependent protein kinase kinases and their involvement in hippocampal dendritic formation
inferred← citeshttps://doi.org/10.1016/j.neures.2012.11.001openalex-snapshot
Single prolonged stress enhances hippocampal glucocorticoid receptor and phosphorylated protein kinase B levels
inferred← citeshttps://doi.org/10.1016/j.neuron.2008.08.021openalex-snapshot
Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity
inferred← citeshttps://doi.org/10.1016/j.neuron.2014.12.063openalex-snapshot
From Intrinsic Firing Properties to Selective Neuronal Vulnerability in Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2004.07.035openalex-snapshot
Chronic treatment with desipramine and fluoxetine modulate BDNF, CaMKKα and CaMKKβ mRNA levels in the hippocampus of transgenic mice expressing antisense RNA against the glucocorticoid receptor
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2008.03.052openalex-snapshot
RETRACTED: Local erythropoietin signaling enhances regeneration in peripheral axons
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2015.05.042openalex-snapshot
Comparison between single and combined post-treatment with S-Methyl-N,N-diethylthiolcarbamate sulfoxide and taurine following transient focal cerebral ischemia in rat brain
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2022.06.007openalex-snapshot
Nrf2 Signaling in the Oxidative Stress Response After Spinal Cord Injury
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2022.08.011openalex-snapshot
Chronic Fluoxetine Treatment of Socially Isolated Rats Modulates Prefrontal Cortex Proteome
inferred← citeshttps://doi.org/10.1016/j.nlm.2011.04.017openalex-snapshot
Forebrain-specific constitutively active CaMKKα transgenic mice show deficits in hippocampus-dependent long-term memory
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2005.10.014openalex-snapshot
The role of the phosphatidylinositide 3-kinase–protein kinase B pathway in schizophrenia
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2016.02.009openalex-snapshot
A beacon of hope in stroke therapy—Blockade of pathologically activated cellular events in excitotoxic neuronal death as potential neuroprotective strategies
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2013.11.006openalex-snapshot
Excitotoxicity and stroke: Identifying novel targets for neuroprotection
inferred← citeshttps://doi.org/10.1016/j.sajb.2015.04.013openalex-snapshot
Sutherlandia frutescens treatment induces apoptosis and modulates the PI3-kinase pathway in colon cancer cells
inferred← citeshttps://doi.org/10.1016/j.sajb.2022.01.036openalex-snapshot
Extracellular proteins of Trichoderma and their role in plant health
inferred← citeshttps://doi.org/10.1016/j.semcancer.2019.06.002openalex-snapshot
Akt in cancer: Mediator and more
inferred← citeshttps://doi.org/10.1016/j.taap.2005.10.005openalex-snapshot
Ketamine-induced apoptosis in cultured rat cortical neurons
inferred← citeshttps://doi.org/10.1016/j.toxlet.2010.05.001openalex-snapshot
Quercetin impairs learning and memory in normal mice via suppression of hippocampal phosphorylated cyclic AMP response element-binding protein expression
inferred← citeshttps://doi.org/10.1016/j.vetimm.2017.04.005openalex-snapshot
Unveiling the participation of avian kinin ornithokinin and its receptors in the chicken inflammatory response
inferred← citeshttps://doi.org/10.1016/j.vetmic.2019.02.013openalex-snapshot
Inhibition of calmodulin increases intracellular survival of Salmonella in chicken macrophage cells
inferred← citeshttps://doi.org/10.1016/j.virol.2006.05.002openalex-snapshot
Papillomavirus virus-like particles activate the PI3-kinase pathway via alpha-6 beta-4 integrin upon binding
inferred← citeshttps://doi.org/10.1016/j.yexcr.2003.10.023openalex-snapshot
Effects of PU.1-induced mouse calcium–calmodulin-dependent kinase I-like kinase (CKLiK) on apoptosis of murine erythroleukemia cells
inferred← citeshttps://doi.org/10.1016/j.yexcr.2007.12.028openalex-snapshot
An endogenous calcium-dependent, caspase-independent intranuclear degradation pathway in thymocyte nuclei: Antagonism by physiological concentrations of K+ ions
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2016.08.013openalex-snapshot
Neuronal Ca 2+ sensor-1 contributes to stress tolerance in cardiomyocytes via activation of mitochondrial detoxification pathways
inferred← citeshttps://doi.org/10.1016/s0006-291x(03)00646-6openalex-snapshot
Cloning of zebrafish BAD, a BH3-only proapoptotic protein, whose overexpression leads to apoptosis in COS-1 cells and zebrafish embryos
inferred← citeshttps://doi.org/10.1016/s0006-8993(00)02284-8openalex-snapshot
Membrane depolarization-mediated survival of sympathetic neurons occurs through both phosphatidylinositol 3-kinase- and CaM kinase II-dependent pathways
inferred← citeshttps://doi.org/10.1016/s0006-8993(01)03045-1openalex-snapshot
Distinct phosphorylation patterns underlie Akt activation by different survival factors in neurons
inferred← citeshttps://doi.org/10.1016/s0006-8993(99)01643-1openalex-snapshot
Nerve growth factor-induced PKB/Akt activity is sustained by phosphoinositide 3-kinase dependent and independent signals in sympathetic neurons
inferred← citeshttps://doi.org/10.1016/s0014-2999(02)01837-xopenalex-snapshot
Regulation of gene expression by Ca2+ signals in neuronal cells
inferred← citeshttps://doi.org/10.1016/s0014-5793(03)00055-3openalex-snapshot
Calcium regulates the PI3K‐Akt pathway in stretched osteoblasts
inferred← citeshttps://doi.org/10.1016/s0022-3565(24)29451-9openalex-snapshot
Growth Factor Signaling in Cell Survival: Implications for Cancer Treatment
inferred← citeshttps://doi.org/10.1016/s0024-3205(03)00092-4openalex-snapshot
Increased intracellular calcium activates serum and glucocorticoid-inducible kinase 1 (SGK1) through a calmodulin-calcium calmodulin dependent kinase kinase pathway in Chinese hamster ovary cells
inferred← citeshttps://doi.org/10.1016/s0076-6879(00)25453-0openalex-snapshot
In vivo activity of wild-type and mutant PAKs
inferred← citeshttps://doi.org/10.1016/s0092-8674(00)80595-4openalex-snapshot
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
inferred← citeshttps://doi.org/10.1016/s0143416002002014openalex-snapshot
Endoplasmic reticulum, Bcl-2 and Ca2+ handling in apoptosis
inferred← citeshttps://doi.org/10.1016/s0166-2236(02)00040-1openalex-snapshot
The Yin and Yang of NMDA receptor signalling
inferred← citeshttps://doi.org/10.1016/s0166-2236(99)01500-3openalex-snapshot
Is CREB a key to neuronal survival?
inferred← citeshttps://doi.org/10.1016/s0167-7306(06)41013-9openalex-snapshot
The calcium/calmodulin-dependent protein kinase cascades
inferred← citeshttps://doi.org/10.1016/s0168-0102(00)00209-1openalex-snapshot
Immunohistochemical localization of Ca2+/calmodulin-dependent protein kinase kinase β in the rat central nervous system
inferred← citeshttps://doi.org/10.1016/s0169-328x(02)00665-4openalex-snapshot
Gene expression changes in single dentate granule neurons after adrenalectomy of rats
inferred← citeshttps://doi.org/10.1016/s0278-5846(03)00173-8openalex-snapshot
Activation of protein kinase B (Akt) signaling after electroconvulsive shock in the rat hippocampus
inferred← citeshttps://doi.org/10.1016/s0301-472x(99)00108-3openalex-snapshot
Modulation of a calcium/calmodulin-dependent protein kinase cascade by retinoic acid during neutrophil maturation
inferred← citeshttps://doi.org/10.1016/s0304-3940(02)00960-6openalex-snapshot
Hypoxic condition interferes with phosphorylation of Akt at Thr308 in cultured rat pheochromocytoma-12 cells
inferred← citeshttps://doi.org/10.1016/s0306-4522(99)00288-2openalex-snapshot
Sphingosine-1-phosphate induces apoptosis of cultured hippocampal neurons that requires protein phosphatases and activator protein-1 complexes
inferred← citeshttps://doi.org/10.1016/s0753-3322(02)00285-8openalex-snapshot
II. Glutamine and glutamate
inferred← citeshttps://doi.org/10.1016/s0896-6273(02)00654-2openalex-snapshot
Phosphorylation of CBP Mediates Transcriptional Activation by Neural Activity and CaM Kinase IV
inferred← citeshttps://doi.org/10.1016/s0896-6273(02)00821-8openalex-snapshot
Akt1 Regulates a JNK Scaffold during Excitotoxic Apoptosis
inferred← citeshttps://doi.org/10.1016/s0896-6273(03)00356-8openalex-snapshot
Control of Synaptic Strength, a Novel Function of Akt
inferred← citeshttps://doi.org/10.1016/s0898-6568(03)00094-9openalex-snapshot
Tyrosine phosphorylation-dependent PI 3 kinase/Akt signal transduction regulates TGFβ-induced fibronectin expression in mesangial cells
inferred← citeshttps://doi.org/10.1016/s0955-0674(00)00228-3openalex-snapshot
Ion homeostasis and apoptosis
inferred← citeshttps://doi.org/10.1016/s0968-0004(99)01383-3openalex-snapshot
The Ca2+–calmodulin-dependent protein kinase cascade
inferred← citeshttps://doi.org/10.1016/s1016-8478(23)13216-xopenalex-snapshot
Ethanol Induces Cell Death by Activating Caspase-3 in the Rat Cerebral Cortex
inferred← citeshttps://doi.org/10.1016/s1043-6618(03)00245-7openalex-snapshot
Apoptosis induced by simvastatin in rat vascular smooth muscle cell through Ca2+-calpain and caspase-3 dependent pathway
inferred← citeshttps://doi.org/10.1016/s1535-6108(03)00303-9openalex-snapshot
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells
inferred← citeshttps://doi.org/10.1016/s1569-2582(04)15004-6openalex-snapshot
4. MECHANISMS OF BILE FORMATION AND CHOLESTASIS
inferred← citeshttps://doi.org/10.1021/acs.biochem.0c00149openalex-snapshot
Development and Characterization of Novel Molecular Probes for Ca2+/Calmodulin-Dependent Protein Kinase Kinase, Derived from STO-609
inferred← citeshttps://doi.org/10.1021/acs.biochem.1c00796openalex-snapshot
Conformation-Dependent Reversible Interaction of Ca2+/Calmodulin-Dependent Protein Kinase Kinase with an Inhibitor, TIM-063
inferred← citeshttps://doi.org/10.1021/acs.biochem.5b00149openalex-snapshot
Analysis of Distinct Roles of CaMKK Isoforms Using STO-609-Resistant Mutants in Living Cells
inferred← citeshttps://doi.org/10.1021/acs.biochem.5c00477openalex-snapshot
Characterization of Autonomous and Ca2+/Calmodulin-Dependent Activities of CaMKK Isoforms In Vitro and in Mouse Tissues
inferred← citeshttps://doi.org/10.1021/acs.est.5c15700openalex-snapshot
Conformation of CD40LG and ANXA5 as Key Events of 2,7-Dibromocarbazole-Induced Cardiotoxicity Using in Vivo and in Vitro Models
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c02274openalex-snapshot
Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.7b00515openalex-snapshot
Scalaradial Is a Potent Inhibitor of Transient Receptor Potential Melastatin 2 (TRPM2) Ion Channels
inferred← citeshttps://doi.org/10.1021/acs.jproteome.1c00008openalex-snapshot
Molecular Profiling Associated with Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2)-Mediated Carcinogenesis in Gastric Cancer
inferred← citeshttps://doi.org/10.1021/acschembio.0c00821openalex-snapshot
Stabilization of Protein–Protein Interactions between CaMKK2 and 14–3–3 by Fusicoccins
inferred← citeshttps://doi.org/10.1021/bi201005gopenalex-snapshot
Generation of Autonomous Activity of Ca2+/Calmodulin-Dependent Protein Kinase Kinase β by Autophosphorylation
inferred← citeshttps://doi.org/10.1021/bi702528ropenalex-snapshot
Activation of SAD Kinase by Ca2+/Calmodulin-Dependent Protein Kinase Kinase
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