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p53 mutant mice that display early ageing-associated phenotypes

https://doi.org/10.1038/415045a
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-3-642-76912-2_2openalex-snapshot
Evaluating Functional Abilities of Primitive Hematopoietic Stem Cell Populations
inferredcites →https://doi.org/10.1016/0014-4827(91)90453-2openalex-snapshot
A role for both RB and p53 in the regulation of human cellular senescence*1
inferredcites →https://doi.org/10.1016/0021-9681(83)90053-xopenalex-snapshot
Aging of physiological systems
inferredcites →https://doi.org/10.1016/0092-8674(90)90113-sopenalex-snapshot
Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53
inferredcites →https://doi.org/10.1016/0092-8674(95)90165-5openalex-snapshot
Small peptides activate the latent sequence-specific DNA binding function of p53
inferredcites →https://doi.org/10.1016/0168-9525(86)90275-1openalex-snapshot
Manipulating the mouse embryo: A laboratory manual
inferredcites →https://doi.org/10.1016/0531-5565(88)90034-4openalex-snapshot
Biomarkers of aging: Tissue markers. Future research needs, strategies, directions and priorities
inferredcites →https://doi.org/10.1016/0531-5565(95)02067-5openalex-snapshot
Handbook of physiology, section 11: Aging
inferredcites →https://doi.org/10.1016/8756-3282(91)90039-lopenalex-snapshot
Structural changes in aging bone: Osteopenia in the proximal femurs of female mice
inferredcites →https://doi.org/10.1016/s0092-8674(00)80580-2openalex-snapshot
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
inferredcites →https://doi.org/10.1016/s0092-8674(00)80762-xopenalex-snapshot
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
inferredcites →https://doi.org/10.1016/s0092-8674(00)81871-1openalex-snapshot
p53, the Cellular Gatekeeper for Growth and Division
inferredcites →https://doi.org/10.1016/s0092-8674(00)81902-9openalex-snapshot
Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
inferredcites →https://doi.org/10.1016/s0092-8674(05)80007-8openalex-snapshot
Activation of p53 sequence-specific DNA bindingby short single strands of DNA requires the p53 C-terminus
inferredcites →https://doi.org/10.1016/s0195-5616(99)50055-7openalex-snapshot
Management of Geriatric Patients
inferredcites →https://doi.org/10.1016/s0531-5565(96)00068-xopenalex-snapshot
Pathobiology of the senescence-accelerated mouse (SAM)
inferredcites →https://doi.org/10.1016/s0733-8635(18)30227-4openalex-snapshot
Wound Healing and Aging
inferredcites →https://doi.org/10.1016/s0960-9822(00)00002-6openalex-snapshot
Tumor spectrum analysis in p53-mutant mice
inferredcites →https://doi.org/10.1038/350243a0openalex-snapshot
Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells
inferredcites →https://doi.org/10.1038/356215a0openalex-snapshot
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
inferredcites →https://doi.org/10.1038/382448a0openalex-snapshot
Increased bone formation in osteocalcin-deficient mice
inferredcites →https://doi.org/10.1038/46311openalex-snapshot
The p66shc adaptor protein controls oxidative stress response and life span in mammals
inferredcites →https://doi.org/10.1038/nm0697-632openalex-snapshot
Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain
inferredcites →https://doi.org/10.1046/j.1432-1327.2001.02228.xopenalex-snapshot
Regulation of cellular senescence by p53
inferredcites →https://doi.org/10.1073/pnas.92.18.8348openalex-snapshot
Increased activity of p53 in senescing fibroblasts.
inferredcites →https://doi.org/10.1073/pnas.95.11.6079openalex-snapshot
Identification of an additional negative regulatory region for p53 sequence-specific DNA binding
inferredcites →https://doi.org/10.1073/pnas.96.19.10770openalex-snapshot
Deletion of Ku86 causes early onset of senescence in mice
inferredcites →https://doi.org/10.1093/emboj/17.16.4657openalex-snapshot
Retention of wild‐type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation
inferredcites →https://doi.org/10.1101/gad.10.9.1054openalex-snapshot
p53: puzzle and paradigm.
inferredcites →https://doi.org/10.1101/gad.12.19.2973openalex-snapshot
The complexity of p53 modulation: emerging patterns from divergent signals
inferredcites →https://doi.org/10.1111/j.1532-5415.1997.tb05175.xopenalex-snapshot
Aging and Cancer: The Double‐Edged Sword of Replicative Senescence
inferredcites →https://doi.org/10.1128/mcb.18.3.1611openalex-snapshot
Reinitiation of DNA Synthesis and Cell Division in Senescent Human Fibroblasts by Microinjection of Anti-p53 Antibodies
inferredcites →https://doi.org/10.1128/mcb.19.5.3395openalex-snapshot
Reactivation of Mutant p53 through Interaction of a C-Terminal Peptide with the Core Domain
inferredcites →https://doi.org/10.1128/mcb.20.11.3772-3780.2000openalex-snapshot
Analysis of ku80-Mutant Mice and Cells with Deficient Levels of p53
inferredcites →https://doi.org/10.1128/mcb.20.14.5248-5255.2000openalex-snapshot
Delayed Wound Healing in Keratin 6a Knockout Mice
inferredcites →https://doi.org/10.1128/mcb.20.8.2803-2808.2000openalex-snapshot
Posttranslational Modifications of p53 in Replicative Senescence Overlapping but Distinct from Those Induced by DNA Damage
inferredcites →https://doi.org/10.1128/mcb.9.9.3982openalex-snapshot
High Incidence of Lung, Bone, and Lymphoid Tumors in Transgenic Mice Overexpressing Mutant Alleles of the p53 Oncogene
inferredcites →https://doi.org/10.1289/ehp.919359openalex-snapshot
Senescence As a Mode of Tumor Suppression

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Comparison Of Cancer Incidence In Domesticated Versus Wild Animals, As The New Insight Into The Cause And Prevention Of Cancer In Humans
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Gorab deficiency in skin dermis accelerates aging and is associated with dysregulation of RCHY1 ‐mediated P53 ubiquitination
inferred← citeshttps://doi.org/10.1002/ange.200600611openalex-snapshot
p53 – ein natürlicher Krebskiller: Einsichten in die Struktur und Therapiekonzepte
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p53—A Natural Cancer Killer: Structural Insights and Therapeutic Concepts
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Hyperkeratosis in cystathionine beta synthase‐deficient mice: An animal model of hyperhomocysteinemia
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p53 and ageing: too much of a good thing?
inferred← citeshttps://doi.org/10.1002/bies.20489openalex-snapshot
Autophagy in neuronal cell loss: a road to death
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Cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity
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Thioredoxin‐binding protein‐2 (TBP‐2): Its potential roles in the aging process
inferred← citeshttps://doi.org/10.1002/ddr.20261openalex-snapshot
New developments in small molecules targeting p53 pathways in anticancer therapy
inferred← citeshttps://doi.org/10.1002/dvdy.24388openalex-snapshot
The effects of proliferation and DNA damage on hematopoietic stem cell function determine aging
inferred← citeshttps://doi.org/10.1002/emmm.201101075openalex-snapshot
Loss of a single allele for Ku80 leads to progenitor dysfunction and accelerated aging in skeletal muscle
inferred← citeshttps://doi.org/10.1002/ggn2.10025openalex-snapshot
How can aging be reversed? Exploring rejuvenation from a damage‐based perspective
inferred← citeshttps://doi.org/10.1002/humu.22507openalex-snapshot
Insights into Wild-Type and Mutant p53 Functions Provided by Genetically Engineered Mice
inferred← citeshttps://doi.org/10.1002/ijc.20968openalex-snapshot
Pilot screening programme for small molecule activators of p53
inferred← citeshttps://doi.org/10.1002/jat.1642openalex-snapshot
Regulation of intracellular Ca2+ by reactive oxygen species in osteoblasts treated with antimycin A
inferred← citeshttps://doi.org/10.1002/jbmr.3564openalex-snapshot
The Spectrum of Fundamental Basic Science Discoveries Contributing to Organismal Aging
inferred← citeshttps://doi.org/10.1002/jcb.21383openalex-snapshot
Cellular and organismal ageing: Role of the p53 tumor suppressor protein in the induction of transient and terminal senescence
inferred← citeshttps://doi.org/10.1002/jcb.24782openalex-snapshot
Combined Usage of Stem Cells in End‐Stage Heart Failure Therapies
inferred← citeshttps://doi.org/10.1002/jcp.10104openalex-snapshot
Does p53 affect organismal aging?
inferred← citeshttps://doi.org/10.1002/jcp.10392openalex-snapshot
Resistance to UV‐induced apoptosis in human keratinocytes during accelerated senescence is associated with functional inactivation of p53
inferred← citeshttps://doi.org/10.1002/jcp.22119openalex-snapshot
Glycolysis links p53 function with NF‐κB signaling: Impact on cancer and aging process
inferred← citeshttps://doi.org/10.1002/jcp.22561openalex-snapshot
The p53 tumor suppressor protein regulates hematopoietic stem cell fate
inferred← citeshttps://doi.org/10.1002/jcp.26825openalex-snapshot
Is the secret for a successful aging to keep track of cancer pathways?
inferred← citeshttps://doi.org/10.1002/jcp.27521openalex-snapshot
MicroRNA‐145 induces the senescence of activated hepatic stellate cells through the activation of p53 pathway by ZEB2
inferred← citeshttps://doi.org/10.1002/jor.22204openalex-snapshot
An overview of underlying causes and animal models for the study of age‐related degenerative disorders of the spine and synovial joints
inferred← citeshttps://doi.org/10.1002/mc.20149openalex-snapshot
Mutant human tumor suppressor p53 modulates the activation of mitogen‐activated protein kinase and nuclear factor‐κB, but not c‐Jun N‐terminal kinase and activated protein‐1
inferred← citeshttps://doi.org/10.1002/mco2.244openalex-snapshot
Mechanistic advances in osteoporosis and anti‐osteoporosis therapies
inferred← citeshttps://doi.org/10.1002/mnfr.70305openalex-snapshot
Unveiling Nutraceuticals That Modulate Aging Mechanism: Exploring the Intricate Pathways of Epigenetics
inferred← citeshttps://doi.org/10.1002/path.1698openalex-snapshot
New approaches for modelling cancer mechanisms in the mouse
inferred← citeshttps://doi.org/10.1002/path.2086openalex-snapshot
p53: at the crossroad between cancer and ageing
inferred← citeshttps://doi.org/10.1002/pmic.200300562openalex-snapshot
Differential expression of the liver proteome in senescence accelerated mice
inferred← citeshttps://doi.org/10.1002/pmic.201200463openalex-snapshot
Quantitative proteomic analysis reveals induction of premature senescence in human umbilical vein endothelial cells exposed to chronic low‐dose rate gamma radiation
inferred← citeshttps://doi.org/10.1002/rmb2.12221openalex-snapshot
Cancer driver mutations in endometriosis: Variations on the major theme of fibrogenesis
inferred← citeshttps://doi.org/10.1002/stem.1925openalex-snapshot
p53 Loss Increases the Osteogenic Differentiation of Bone Marrow Stromal Cells
inferred← citeshttps://doi.org/10.1002/stem.54openalex-snapshot
Downregulation of APE1/Ref-1 Is Involved in the Senescence of Mesenchymal Stem Cells
inferred← citeshttps://doi.org/10.1007/0-387-29390-6_3openalex-snapshot
The Role of Presenilins in the Cell Cycle and Apoptosis
inferred← citeshttps://doi.org/10.1007/1-4020-5058-5_1openalex-snapshot
Biological causes of aging and age-related diseases
inferred← citeshttps://doi.org/10.1007/1-4020-8107-3_8openalex-snapshot
P53 and other Cell Cycle Regulators
inferred← citeshttps://doi.org/10.1007/978-0-387-40049-5_15openalex-snapshot
Post-translational Modifications of the p53 Transcription Factor
inferred← citeshttps://doi.org/10.1007/978-0-387-69132-9openalex-snapshot
Mouse models of human blood cancers : basic research and pre-clinical applications
inferred← citeshttps://doi.org/10.1007/978-0-387-69132-9_6openalex-snapshot
Dietary Restriction: A Model System Probing the Cell Fate Decision Between Cancer and Senescence
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Dysfunction of the Ubiquitin/Proteasome System and Mitochondria in Neurodegenerative Disease
inferred← citeshttps://doi.org/10.1007/978-1-0716-0741-1_1openalex-snapshot
Introduction to Genes, Oncogenes, and Anti-oncogenes
inferred← citeshttps://doi.org/10.1007/978-1-4020-2922-6_8openalex-snapshot
Manipulating the p53 Gene in the Mouse: Organismal Functions of a Prototype Tumor Suppressor
inferred← citeshttps://doi.org/10.1007/978-1-4020-4848-7_1openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-1-4020-9063-9_3openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-1-4419-0639-7_13openalex-snapshot
Contributions of Tumor Suppressors to the Epigenetic Regulation of Aging Cells
inferred← citeshttps://doi.org/10.1007/978-1-4419-0892-6_15openalex-snapshot
Biology of Aging
inferred← citeshttps://doi.org/10.1007/978-1-4419-6999-6_2openalex-snapshot
Cell and Molecular Aging
inferred← citeshttps://doi.org/10.1007/978-1-4419-7002-2_13openalex-snapshot
Post-Translational Modification of Cellular Proteins by Ubiquitin and Ubiquitin-Like Molecules: Role in Cellular Senescence and Aging
inferred← citeshttps://doi.org/10.1007/978-1-4419-8231-5_2openalex-snapshot
Lessons on p53 from Mouse Models
inferred← citeshttps://doi.org/10.1007/978-1-4614-6828-8_18openalex-snapshot
Role of Par-4 in Prostate Cancer
inferred← citeshttps://doi.org/10.1007/978-1-4614-9557-4_5openalex-snapshot
DNA Damage Caused by Oral Malodorous Compounds in Periodontal Cells In Vitro: Novel Carcinogenic Pathway
inferred← citeshttps://doi.org/10.1007/978-1-4939-2404-2_2openalex-snapshot
Candidate Genes That Affect Aging Through Protein Homeostasis
inferred← citeshttps://doi.org/10.1007/978-1-59259-785-7_22openalex-snapshot
Chemosensitization
inferred← citeshttps://doi.org/10.1007/978-1-59745-021-8_36openalex-snapshot
Mammalian Sir2 Proteins
inferred← citeshttps://doi.org/10.1007/978-1-59745-199-4_16openalex-snapshot
Intracellular Pathways Involved in DNA Damage and Repair to Neuronal Apoptosis
inferred← citeshttps://doi.org/10.1007/978-1-59745-274-8_2openalex-snapshot
Targeting the p53/MDM2 Pathway for Cancer Therapy
inferred← citeshttps://doi.org/10.1007/978-1-59745-435-3openalex-snapshot
Cellular Respiration and Carcinogenesis
inferred← citeshttps://doi.org/10.1007/978-1-59745-435-3_7openalex-snapshot
The Role of Glycolysis in Cellular Immortalization
inferred← citeshttps://doi.org/10.1007/978-1-59745-474-2_12openalex-snapshot
p53 Inhibitors as Cancer Sensitizing Agents
inferred← citeshttps://doi.org/10.1007/978-1-60327-227-8_6openalex-snapshot
Genomic Stability in Stem Cells
inferred← citeshttps://doi.org/10.1007/978-1-60327-507-1_11openalex-snapshot
Aging and Longevity in Animal Models and Humans
inferred← citeshttps://doi.org/10.1007/978-1-60327-553-8_14openalex-snapshot
p53 Pathway Alterations in Brain Tumors
inferred← citeshttps://doi.org/10.1007/978-1-60327-879-9_6openalex-snapshot
Mouse Model: Telomeres and Telomerase in Stem Cell and Cancer
inferred← citeshttps://doi.org/10.1007/978-1-62703-239-1_3openalex-snapshot
Senescence Regulation by the p53 Protein Family
inferred← citeshttps://doi.org/10.1007/978-1-62703-739-6_25openalex-snapshot
Mutation Screening of the TP53 Gene by Temporal Temperature Gel Electrophoresis (TTGE)
inferred← citeshttps://doi.org/10.1007/978-1-84628-697-1_5openalex-snapshot
Animal Models for Senile Osteoporosis
inferred← citeshttps://doi.org/10.1007/978-1-84800-265-4_1openalex-snapshot
Basic Science of Breast Cancer in Older Patients
inferred← citeshttps://doi.org/10.1007/978-2-8178-0142-1_3openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-3-030-44903-2_9openalex-snapshot
Novel Probes and Carriers to Target Senescent Cells
inferred← citeshttps://doi.org/10.1007/978-3-030-73774-0_6openalex-snapshot
Aging in the Human Species
inferred← citeshttps://doi.org/10.1007/978-3-030-73774-0_7openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-3-031-28624-7_11openalex-snapshot
Metabolic/Endocrine Disorders
inferred← citeshttps://doi.org/10.1007/978-3-031-28624-7_13openalex-snapshot
Bone Neoplasia and Skeletal Dysplasia
inferred← citeshttps://doi.org/10.1007/978-3-031-28624-7_9openalex-snapshot
Infectious Disease
inferred← citeshttps://doi.org/10.1007/978-3-319-03970-1_7openalex-snapshot
Effects of Aging on the Cellular Function, Healing, and Mechanical Properties of Ligaments
inferred← citeshttps://doi.org/10.1007/978-3-319-23246-1_3openalex-snapshot
The Impact of Aging on Cancer Progression and Treatment
inferred← citeshttps://doi.org/10.1007/978-3-319-25976-5_6openalex-snapshot
Animal Models for Aging Bone
inferred← citeshttps://doi.org/10.1007/978-3-319-26239-0_9openalex-snapshot
Cell Cycle Checkpoints and Senescence
inferred← citeshttps://doi.org/10.1007/978-3-319-44703-2_11openalex-snapshot
Genome Stability and Ageing
inferred← citeshttps://doi.org/10.1007/978-3-319-44870-1_71-1openalex-snapshot
Hematopoietic Stem Cell Aging and Malignant Hemopathies
inferred← citeshttps://doi.org/10.1007/978-3-319-57415-8_71openalex-snapshot
Hematopoietic Stem Cell Aging and Malignant Hemopathies
inferred← citeshttps://doi.org/10.1007/978-3-319-64597-1_142-1openalex-snapshot
Aging and Malignant Hemopathies: A Complex Multistep Process
inferred← citeshttps://doi.org/10.1007/978-3-319-64597-1_3-1openalex-snapshot
Mouse Models and Genetics of Immunosenescence
inferred← citeshttps://doi.org/10.1007/978-3-319-97919-9_4openalex-snapshot
Background on Biology of Ageing and Bioinformatics
inferred← citeshttps://doi.org/10.1007/978-3-319-99375-1_142openalex-snapshot
Aging and Malignant Hemopathies: A Complex Multistep Process
inferred← citeshttps://doi.org/10.1007/978-3-319-99375-1_3openalex-snapshot
Mouse Models and Genetics of Immunosenescence
inferred← citeshttps://doi.org/10.1007/978-3-540-34449-0_9openalex-snapshot
Altered Splicing in Prelamin A-Associated Premature Aging Phenotypes
inferred← citeshttps://doi.org/10.1007/978-3-540-37005-5_8openalex-snapshot
Aging and the programmed death phenomena
inferred← citeshttps://doi.org/10.1007/978-3-540-73709-4_4openalex-snapshot
Initiation of Genomic Instability, Cellular Senescence, and Organismal Aging by Dysfunctional Telomeres
inferred← citeshttps://doi.org/10.1007/978-3-540-73709-4_6openalex-snapshot
Mechanisms of Stem Cell Ageing
inferred← citeshttps://doi.org/10.1007/978-3-540-73709-4_8openalex-snapshot
Telomere Shortening Induces Cell Intrinsic Checkpoints and Environmental Alterations Limiting Adult Stem Cell Function
inferred← citeshttps://doi.org/10.1007/978-3-540-73709-4_9openalex-snapshot
p16INK4a and Stem Cell Ageing: A Telomere-Independent Process?
inferred← citeshttps://doi.org/10.1007/978-3-642-00150-5_23openalex-snapshot
p53
inferred← citeshttps://doi.org/10.1007/978-3-642-02112-1_21openalex-snapshot
Aging and Cancer: Caretakers and Gatekeepers
inferred← citeshttps://doi.org/10.1007/978-3-642-16602-0_7openalex-snapshot
Nervous System Aging, Degeneration, and the p53 Family
inferred← citeshttps://doi.org/10.1007/978-3-642-18495-6_3openalex-snapshot
Angiotensin as a Cytokine Implicated in Accelerated Cellular Turnover
inferred← citeshttps://doi.org/10.1007/978-3-642-18932-6_7openalex-snapshot
The p53 Transcription Factor as Therapeutic Target in Cancer
inferred← citeshttps://doi.org/10.1007/978-3-642-27814-3_120-1openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-3-642-33430-6_15openalex-snapshot
Concept of Aging as a Result of Slow Programmed Poisoning of an Organism with Mitochondrial Reactive Oxygen Species
inferred← citeshttps://doi.org/10.1007/978-3-642-55160-4_8openalex-snapshot
Pulp Aging: Fibrosis and Calcospherites
inferred← citeshttps://doi.org/10.1007/978-3-662-47398-6_120openalex-snapshot
Platinum and Palladium Nanoparticles Regulate the Redox Balance and Protect Against Age-Related Skin Changes in Mice
inferred← citeshttps://doi.org/10.1007/978-3-7643-8336-7_7openalex-snapshot
Chemical induced alterations in p53 signaling
inferred← citeshttps://doi.org/10.1007/978-81-322-2032-9_3openalex-snapshot
Oxidative Stress in Metabolic Disorders/Diseases
inferred← citeshttps://doi.org/10.1007/978-90-481-2719-1_2openalex-snapshot
The Red Sea, Coastal Landscapes, and Hominin Dispersals
inferred← citeshttps://doi.org/10.1007/978-94-007-0495-4_15openalex-snapshot
Aging
inferred← citeshttps://doi.org/10.1007/978-94-007-7618-0_29openalex-snapshot
Different Expression of P53 and Rb Gene in the Experimental Neuronal Aging with the Interference of Cholecystokinin
inferred← citeshttps://doi.org/10.1007/978-94-010-0064-2_5openalex-snapshot
Programmed Death Phenomena at Various Levels of Development of the Living Systems
inferred← citeshttps://doi.org/10.1007/978-94-017-0669-8_3openalex-snapshot
Aging of Fibroblasts
inferred← citeshttps://doi.org/10.1007/978-94-017-0669-8_5openalex-snapshot
In Vitro Senescence of Human Osteoblasts
inferred← citeshttps://doi.org/10.1007/978-94-017-0669-8_7openalex-snapshot
Aging of Premature-Aging Syndrome Cells
inferred← citeshttps://doi.org/10.1007/978-94-017-0669-8_8openalex-snapshot
The p53 Pathway, Cancer and Aging
inferred← citeshttps://doi.org/10.1007/978-94-017-0673-5_2openalex-snapshot
Aging of the Skin
inferred← citeshttps://doi.org/10.1007/978-94-017-7587-8_4openalex-snapshot
Evidence for Dependence Among Diseases
inferred← citeshttps://doi.org/10.1007/978-94-017-9639-2_8openalex-snapshot
Sentinel Gene Within Cell Territory and Molecular Platforms in Cancer: Methylation Diversity of p53 Gene in Brain Tumors
inferred← citeshttps://doi.org/10.1007/978-94-024-1713-5_7openalex-snapshot
Aging
inferred← citeshttps://doi.org/10.1007/978-981-16-0522-2_3openalex-snapshot
Oxidative Stress-Mediated Stem Cell Aging
inferred← citeshttps://doi.org/10.1007/978-981-32-9267-3_4openalex-snapshot
Results-II. Haploinsufficiency of p53 Rescues Lifespan and Premature Aging-Associated Abnormalities in Sirt6-Deficient Mice
inferred← citeshttps://doi.org/10.1007/978-981-32-9267-3_6openalex-snapshot
Discussion
inferred← citeshttps://doi.org/10.1007/bf02829950openalex-snapshot
Nutrition, sirtuins and aging
inferred← citeshttps://doi.org/10.1007/s00018-007-6381-yopenalex-snapshot
Calorie restriction and the nutrient sensing signaling pathways
inferred← citeshttps://doi.org/10.1007/s00018-007-7123-xopenalex-snapshot
From old organisms to new molecules: integrative biology and therapeutic targets in accelerated human ageing
inferred← citeshttps://doi.org/10.1007/s00018-015-1930-2openalex-snapshot
An integrative view on sex differences in brain tumors
inferred← citeshttps://doi.org/10.1007/s00018-020-03664-yopenalex-snapshot
Endothelial sprouting, proliferation, or senescence: tipping the balance from physiology to pathology
inferred← citeshttps://doi.org/10.1007/s00018-023-04964-9openalex-snapshot
Intracellular FGF1 protects cells from apoptosis through direct interaction with p53
inferred← citeshttps://doi.org/10.1007/s00223-002-1041-6openalex-snapshot
Induction of p53 Expression and Function by Estrogen in Osteoblasts
inferred← citeshttps://doi.org/10.1007/s00223-011-9533-xopenalex-snapshot
Osteocalcin Gene Expression Is Regulated by Wild-Type p53
inferred← citeshttps://doi.org/10.1007/s00262-008-0639-6openalex-snapshot
Why do centenarians escape or postpone cancer? The role of IGF-1, inflammation and p53
inferred← citeshttps://doi.org/10.1007/s00774-004-0517-zopenalex-snapshot
Progeroid syndrome as a model for impaired bone formation in senile osteoporosis
inferred← citeshttps://doi.org/10.1007/s00774-022-01314-wopenalex-snapshot
p53 deficiency promotes bone regeneration by functional regulation of mesenchymal stromal cells and osteoblasts
inferred← citeshttps://doi.org/10.1007/s10462-017-9541-yopenalex-snapshot
An empirical evaluation of hierarchical feature selection methods for classification in bioinformatics datasets with gene ontology-based features
inferred← citeshttps://doi.org/10.1007/s10495-010-0559-8openalex-snapshot
Mutant p53 exhibits trivial effects on mitochondrial functions which can be reactivated by ellipticine in lymphoma cells
inferred← citeshttps://doi.org/10.1007/s10522-005-4901-4openalex-snapshot
Telomeres and Telomerase Biology in Vertebrates: Progress Towards a Non-Human Model for Replicative Senescence and Ageing
inferred← citeshttps://doi.org/10.1007/s10522-008-9136-8openalex-snapshot
Glycerol stimulates innate chaperoning, proteasomal and stress-resistance functions: implications for geronto-manipulation
inferred← citeshttps://doi.org/10.1007/s10522-011-9343-6openalex-snapshot
Is rate of skin wound healing associated with aging or longevity phenotype?
inferred← citeshttps://doi.org/10.1007/s10522-014-9529-9openalex-snapshot
Senescent cells: SASPected drivers of age-related pathologies
inferred← citeshttps://doi.org/10.1007/s10522-015-9593-9openalex-snapshot
Premature aging/senescence in cancer cells facing therapy: good or bad?
inferred← citeshttps://doi.org/10.1007/s10555-011-9342-8openalex-snapshot
A new hypothesis for the cancer mechanism
inferred← citeshttps://doi.org/10.1007/s10709-020-00088-1openalex-snapshot
Apoptosis inhibition mitigates aging effects in Drosophila melanogaster
inferred← citeshttps://doi.org/10.1007/s10989-021-10353-2openalex-snapshot
Emerging Therapeutic Potential of Short Mitochondrial-produced Peptides for Anabolic Osteogenesis
inferred← citeshttps://doi.org/10.1007/s11010-007-9561-zopenalex-snapshot
RNA interference in human foreskin fibroblasts within the three-dimensional collagen matrix
inferred← citeshttps://doi.org/10.1007/s11010-025-05355-3openalex-snapshot
Balancing senescence and apoptosis: therapeutic insights into aging and cancer
inferred← citeshttps://doi.org/10.1007/s11248-010-9422-5openalex-snapshot
Continuous oxidative stress due to activation of polyamine catabolism accelerates aging and protects against hepatotoxic insults
inferred← citeshttps://doi.org/10.1007/s11356-023-28065-zopenalex-snapshot
Joint effects of phenol, chlorophenol pesticide, phthalate, and polycyclic aromatic hydrocarbon on bone mineral density: comparison of four statistical models
inferred← citeshttps://doi.org/10.1007/s11357-002-0006-zopenalex-snapshot
Stem cells from birth to death: The history and the future
inferred← citeshttps://doi.org/10.1007/s11357-005-4556-8openalex-snapshot
Twenty years of progress in biogerontology research
inferred← citeshttps://doi.org/10.1007/s11357-006-9010-zopenalex-snapshot
Extension of mouse lifespan by overexpression of catalase
inferred← citeshttps://doi.org/10.1007/s11357-009-9108-1openalex-snapshot
Cellular senescence: unravelling complexity
inferred← citeshttps://doi.org/10.1007/s11357-021-00460-9openalex-snapshot
Divergent regulation of lncRNA expression by ischemia in adult and aging mice
inferred← citeshttps://doi.org/10.1007/s11357-026-02154-6openalex-snapshot
Genome-wide association study of frailty and integrative functional analysis to elucidate its relationship with aging
inferred← citeshttps://doi.org/10.1007/s11427-007-0024-2openalex-snapshot
Effect of cell cycle inhibitor p19ARF on senescence of human diploid cell
inferred← citeshttps://doi.org/10.1007/s11427-022-2161-3openalex-snapshot
The landscape of aging
inferred← citeshttps://doi.org/10.1007/s11515-011-0970-8openalex-snapshot
Tumor suppressor p53: new functions of an old protein
inferred← citeshttps://doi.org/10.1007/s11655-021-2861-4openalex-snapshot
Homeostasis Research Model Based on Yin-Yang Theory: Five Examples
inferred← citeshttps://doi.org/10.1007/s11692-013-9268-xopenalex-snapshot
Trojan Genes or Transparent Genomes? Sexual Selection and Potential Impacts of Genetically Modified Animals in Natural Ecosystems
inferred← citeshttps://doi.org/10.1007/s11914-011-0054-3openalex-snapshot
FoxOs: Unifying Links Between Oxidative Stress and Skeletal Homeostasis
inferred← citeshttps://doi.org/10.1007/s12011-012-9506-6openalex-snapshot
The Effects of Cobalt on the Development, Oxidative Stress, and Apoptosis in Zebrafish Embryos
inferred← citeshttps://doi.org/10.1007/s12035-019-01800-9openalex-snapshot
Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis
inferred← citeshttps://doi.org/10.1007/s13238-010-0140-9openalex-snapshot
Mdm2 links genotoxic stress and metabolism to p53
inferred← citeshttps://doi.org/10.1007/s13238-011-1063-9openalex-snapshot
The impact of acetylation and deacetylation on the p53 pathway
inferred← citeshttps://doi.org/10.1007/s13258-019-00785-yopenalex-snapshot
Phenotyping analysis of p53 knockout mice produced by gene editing and comparison with conventional p53 knockout mice
inferred← citeshttps://doi.org/10.1007/s40520-016-0617-3openalex-snapshot
Age-related hyperkyphosis: update of its potential causes and clinical impacts—narrative review
inferred← citeshttps://doi.org/10.1007/s40778-015-0020-6openalex-snapshot
The Role of Stem Cell Genomic Instability in Aging
inferred← citeshttps://doi.org/10.1007/s40778-018-0128-6openalex-snapshot
Signaling Pathways Regulating Hematopoietic Stem Cell and Progenitor Aging
inferred← citeshttps://doi.org/10.1016/b978-0-12-375098-3.50007-xopenalex-snapshot
Osteoblast Biology
inferred← citeshttps://doi.org/10.1016/b978-0-12-394447-4.30061-xopenalex-snapshot
Regulation of the p53 Pathway
inferred← citeshttps://doi.org/10.1016/b978-0-12-396971-2.00009-9openalex-snapshot
The Circadian Clock in Cancer Development and Therapy
inferred← citeshttps://doi.org/10.1016/b978-0-12-397803-5.00014-9openalex-snapshot
Organelle Stress and mTOR in Aging-Associated Inflammation
inferred← citeshttps://doi.org/10.1016/b978-0-12-397803-5.00017-4openalex-snapshot
Cellular Senescence and Premature Aging in Lung Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-397920-9.00003-2openalex-snapshot
Mouse Models and Aging
inferred← citeshttps://doi.org/10.1016/b978-0-12-405933-7.00001-9openalex-snapshot
Oxidative Stress and Frailty
inferred← citeshttps://doi.org/10.1016/b978-0-12-405933-7.00014-7openalex-snapshot
Protective Effects of Vitamin C on Age-Related Bone and Skin Phenotypes Caused by Intracellular Reactive Oxygen Species
inferred← citeshttps://doi.org/10.1016/b978-0-12-415853-5.00009-1openalex-snapshot
Osteoblast Biology
inferred← citeshttps://doi.org/10.1016/b978-0-12-418680-4.00021-xopenalex-snapshot
Selenium and Senescence
inferred← citeshttps://doi.org/10.1016/b978-0-12-802389-1.00016-2openalex-snapshot
Chromatin Signaling in Aging and Cellular Senescence
inferred← citeshttps://doi.org/10.1016/b978-0-12-811353-0.00050-6openalex-snapshot
Genetics of Progeria and Aging
inferred← citeshttps://doi.org/10.1016/b978-0-12-811353-0.00059-2openalex-snapshot
Sex and the Aging Immune System
inferred← citeshttps://doi.org/10.1016/b978-0-12-818000-6.00048-2openalex-snapshot
Linking aging and animal models to neurodegeneration
inferred← citeshttps://doi.org/10.1016/b978-0-12-821618-7.00251-0openalex-snapshot
Regulation of the p53 Pathway
inferred← citeshttps://doi.org/10.1016/b978-0-12-823761-8.00031-8openalex-snapshot
Programming of early aging
inferred← citeshttps://doi.org/10.1016/b978-0-443-19001-8.00018-0openalex-snapshot
Chromatin signaling in aging and cellular senescence
inferred← citeshttps://doi.org/10.1016/b978-012088387-5/50005-4openalex-snapshot
Are Age-Associated Diseases an Integral Part of Aging?
inferred← citeshttps://doi.org/10.1016/b978-012088387-5/50009-1openalex-snapshot
p53 and Mouse Aging Models
inferred← citeshttps://doi.org/10.1016/b978-012336425-8/50074-1openalex-snapshot
Gerontology
inferred← citeshttps://doi.org/10.1016/b978-012369391-4/50029-1openalex-snapshot
Zebrafish as Aging Models
inferred← citeshttps://doi.org/10.1016/b978-012369391-4/50050-3openalex-snapshot
Mouse Models of Accelerated Aging
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