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Emodin induces human T cell apoptosis in vitro by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ptr.1752openalex-snapshot
Evaluation of the antibacterial activity ofVentilago madraspatana Gaertn.,Rubia cordifolia Linn. andLantana camara Linn.: isolation of emodin and physcion as active antibacterial agents
inferredcites →https://doi.org/10.1006/abbi.1997.0489openalex-snapshot
Substrate and Site Specificity of Hydrogen Peroxide Generation in Mouse Mitochondria
inferredcites →https://doi.org/10.1007/s000110050727openalex-snapshot
Regulation of cell proliferation, inflammatory cytokine production and calcium mobilization in primary human T lymphocytes by emodin from Polygonum hypoleucum Ohwi
inferredcites →https://doi.org/10.1007/s00018-009-0119-yopenalex-snapshot
Red blood cells carry out T cell growth and survival bioactivities that are sensitive to cyclosporine A
inferredcites →https://doi.org/10.1016/0014-2999(91)90624-yopenalex-snapshot
Vasorelaxants from Chinese herbs, emodin and scoparone, possess immunosuppressive properties
inferredcites →https://doi.org/10.1016/0014-2999(92)90393-iopenalex-snapshot
Immunosuppressive effect of emodin, a free radical generator
inferredcites →https://doi.org/10.1016/j.canlet.2012.12.008openalex-snapshot
Negative regulation of transcription factor FoxM1 by p53 enhances oxaliplatin-induced senescence in hepatocellular carcinoma
inferredcites →https://doi.org/10.1016/j.cellsig.2012.01.008openalex-snapshot
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
inferredcites →https://doi.org/10.1016/j.coi.2009.09.011openalex-snapshot
Regulatory T cells and inhibitory cytokines in autoimmunity
inferredcites →https://doi.org/10.1016/j.ejmech.2012.07.051openalex-snapshot
Synthesis and biological activity evaluation of emodin quaternary ammonium salt derivatives as potential anticancer agents
inferredcites →https://doi.org/10.1016/j.ejphar.2008.06.044openalex-snapshot
Exploration of Emodin to treat alpha-naphthylisothiocyanate-induced cholestatic hepatitis via anti-inflammatory pathway
inferredcites →https://doi.org/10.1016/j.ejphar.2012.04.012openalex-snapshot
Stephanthraniline A inhibits the proliferation and activation of T cells in vitro and in vivo
inferredcites →https://doi.org/10.1016/j.jep.2010.01.031openalex-snapshot
Ophiopogonin D prevents H2O2-induced injury in primary human umbilical vein endothelial cells
inferredcites →https://doi.org/10.1016/j.jep.2011.04.054openalex-snapshot
Macrophages, rather than T and B cells are principal immunostimulatory target cells of Lycium barbarum L. polysaccharide LBPF4-OL
inferredcites →https://doi.org/10.1016/j.jep.2012.02.006openalex-snapshot
In vitro and in vivo antioxidant activity of the ethanolic extract from Meconopsis quintuplinervia
inferredcites →https://doi.org/10.1016/j.jep.2012.09.010openalex-snapshot
JR6, a new compound isolated from Justicia procumbens, induces apoptosis in human bladder cancer EJ cells through caspase-dependent pathway
inferredcites →https://doi.org/10.1016/j.jhep.2004.04.005openalex-snapshot
Herb medicine Inchin-ko-to (TJ-135) regulates PDGF-BB-dependent signaling pathways of hepatic stellate cells in primary culture and attenuates development of liver fibrosis induced by thioacetamide administration in rats
inferredcites →https://doi.org/10.1016/j.transproceed.2009.02.090openalex-snapshot
Immunosuppressive Effects of Emodin: An In Vivo and In Vitro Study
inferredcites →https://doi.org/10.1038/sj.cdd.4401373openalex-snapshot
Roles of CHOP/GADD153 in endoplasmic reticulum stress
inferredcites →https://doi.org/10.1038/sj.emboj.7600596openalex-snapshot
TRB3, a novel ER stress‐inducible gene, is induced via ATF4–CHOP pathway and is involved in cell death
inferredcites →https://doi.org/10.1073/pnas.95.14.7872openalex-snapshot
Lower intracellular hydrogen peroxide levels in cells overexpressing CuZn-superoxide dismutase
inferredcites →https://doi.org/10.1074/jbc.m204973200openalex-snapshot
An Endoplasmic Reticulum Stress-specific Caspase Cascade in Apoptosis
inferredcites →https://doi.org/10.1097/00007890-199910150-00020openalex-snapshot
FK506 MARKEDLY ENHANCES APOPTOSIS OF ANTIGEN-STIMULATED PERIPHERAL T CELLS BY DOWN-REGULATION OF Bcl-xL1
inferredcites →https://doi.org/10.1111/j.1600-6143.2012.04065.xopenalex-snapshot
Low-Dose Rapamycin Treatment Increases the Ability of Human Regulatory T Cells to Inhibit Transplant Arteriosclerosis In Vivo
inferredcites →https://doi.org/10.1111/j.1745-7254.2006.00338.xopenalex-snapshot
Recombinant human B7-H4 expressed in Escherichia coli inhibits T lymphocyte proliferation and IL-2 secretion in vitro1
inferredcites →https://doi.org/10.1158/1541-7786.mcr-05-0221openalex-snapshot
The Unfolded Protein Response: A Novel Component of the Hypoxic Stress Response in Tumors
inferredcites →https://doi.org/10.1172/jci18007openalex-snapshot
T cell apoptosis and reactive oxygen species
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Emerging role of phytochemicals in targeting predictive, prognostic, and diagnostic biomarkers of lung cancer
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The natural anthraquinone dye emodin: Eco/genotoxicological characterization for aquatic organisms
inferred← citeshttps://doi.org/10.1016/j.gene.2016.06.018openalex-snapshot
BmDredd is an initiator caspase and participates in Emodin-induced apoptosis in the silkworm, Bombyx mori
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inferred← citeshttps://doi.org/10.1016/j.intimp.2020.107277openalex-snapshot
Emodin attenuates silica-induced lung injury by inhibition of inflammation, apoptosis and epithelial-mesenchymal transition
inferred← citeshttps://doi.org/10.1016/j.jddst.2015.10.019openalex-snapshot
Pharmacokinetics and tissue distribution of emodin loaded nanoemulsion in rats
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Polydatin: A natural compound with multifaceted anticancer properties
inferred← citeshttps://doi.org/10.1016/j.neuro.2014.11.007openalex-snapshot
ROS act as an upstream signal to mediate cadmium-induced mitophagy in mouse brain
inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2024.106874openalex-snapshot
Dahuang Huanglian Xiexin Decoction ameliorates obesity via modulating adipocyte differentiation and lipid degradation through inhibiting endoplasmic reticulum stress
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d-Alanine 2, Leucine 5 Enkephaline (DADLE)-mediated DOR activation augments human hUCB-BFs viability subjected to oxidative stress via attenuation of the UPR
inferred← citeshttps://doi.org/10.1016/j.tiv.2017.01.022openalex-snapshot
Polygoni Multiflori Radix derived anthraquinones alter bile acid disposition in sandwich-cultured rat hepatocytes
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Differential susceptibility of BRL cells with/without insulin resistance and the role of endoplasmic reticulum stress signaling pathway in response to acrylamide-exposure toxicity effects in vitro
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2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucopyranoside enhances the hepatotoxicity of emodin in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/s1875-5364(20)30050-9openalex-snapshot
The pharmacology, toxicology and therapeutic potential of anthraquinone derivative emodin
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.1c00358openalex-snapshot
Cysteine-Based Protein Covalent Binding and Hepatotoxicity Induced by Emodin
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Emerging Mycotoxins: Beyond Traditionally Determined Food Contaminants
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Antitumor Effect and Toxicity of an Albumin-Paclitaxel Nanocarrier System Constructed via Controllable Alkali-Induced Conformational Changes
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TGF-β downregulation-induced cancer cell death is finely regulated by the SAPK signaling cascade
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Small interfering LncRNA-TUG1 (siTUG1) decreases ketamine-induced neurotoxicity in rat hippocampal neurons
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HPS protects the liver against steatosis, cell death, inflammation, and fibrosis in mice with steatohepatitis
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Emodin, as a mitochondrial uncoupler, induces strong decreases in adenosine triphosphate (ATP) levels and proliferation of B16F10 cells, owing to their poor glycolytic reserve
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Emodin‐Induced Oxidative Inhibition of Mitochondrial Function Assists BiP/IRE1α/CHOP Signaling‐Mediated ER‐Related Apoptosis
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Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway
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Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cells
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Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress apoptosis signaling pathway in ischemia reperfusion-induced acute kidney injury
inferred← citeshttps://doi.org/10.1371/journal.pone.0287517openalex-snapshot
Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway
inferred← citeshttps://doi.org/10.1515/biol-2016-0070openalex-snapshot
The antitumor effects of mitochondria-targeted 6-(nicotinamide) methyl coumarin
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Emodin induces apoptosis and autophagy of fibroblasts obtained from patient with ankylosing spondylitis
inferred← citeshttps://doi.org/10.3109/15376516.2014.943444openalex-snapshot
Cadmium induces mitophagy through ROS-mediated PINK1/Parkin pathway
inferred← citeshttps://doi.org/10.3389/fbioe.2021.784612openalex-snapshot
Reactive Oxygen Species in Anticancer Immunity: A Double-Edged Sword
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The Emerging Roles of Endoplasmic Reticulum Stress in Balancing Immunity and Tolerance in Health and Diseases: Mechanisms and Opportunities
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Comprehensive molecular and cellular characterization of endoplasmic reticulum stress-related key genes in renal ischemia/reperfusion injury
inferred← citeshttps://doi.org/10.3389/fphar.2017.00349openalex-snapshot
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inferred← citeshttps://doi.org/10.3389/fphar.2018.01530openalex-snapshot
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Hepatotoxicity of the Major Anthraquinones Derived From Polygoni Multiflori Radix Based on Bile Acid Homeostasis
inferred← citeshttps://doi.org/10.3389/fphys.2018.01058openalex-snapshot
Oxidative Stress Mediates Microcystin-LR-Induced Endoplasmic Reticulum Stress and Autophagy in KK-1 Cells and C57BL/6 Mice Ovaries
inferred← citeshttps://doi.org/10.3390/ani11113314openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/ijms241310596openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/jof10060369openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/molecules30132808openalex-snapshot
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inferred← citeshttps://doi.org/10.3748/wjg.v20.i41.15289openalex-snapshot
N-acetylcysteine attenuates reactive-oxygen-species-mediated endoplasmic reticulum stress during liver ischemia-reperfusion injury
inferred← citeshttps://doi.org/10.3892/mmr.2016.4909openalex-snapshot
Polydatin-induced cell apoptosis and cell cycle arrest are potentiated by Janus kinase 2 inhibition in leukemia cells
inferred← citeshttps://doi.org/10.3892/ol.2018.8899openalex-snapshot
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inferred← citeshttps://doi.org/10.3906/biy-1705-76openalex-snapshot
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inferred← citeshttps://doi.org/10.4103/0366-6999.181961openalex-snapshot
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