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Time-dependent pharmacokinetics of dexamethasone and its efficacy in human breast cancer xenograft mice: a semi-mechanism-based pharmacokinetic/pharmacodynamic model
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/bdd.626openalex-snapshot
Pharmacokinetics of dexamethasone in a rat model of rheumatoid arthritis
inferredcites →https://doi.org/10.1002/bmc.3316openalex-snapshot
Development and validation of a highly sensitive LC‐MS/MS method for the determination of dexamethasone in nude mice plasma and its application to a pharmacokinetic study
inferredcites →https://doi.org/10.1002/jps.24629openalex-snapshot
Semi-Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for the Combination Use of Dexamethasone and Gemcitabine in Breast Cancer
inferredcites →https://doi.org/10.1002/jps.2600830409openalex-snapshot
A Pharmacodynamic Approach to the Estimate of Carbamazepine Autoinduction
inferredcites →https://doi.org/10.1007/s10928-009-9117-9openalex-snapshot
Modeling of tumor growth and anticancer effects of combination therapy
inferredcites →https://doi.org/10.1007/s11060-007-9342-2openalex-snapshot
Dexamethasone inhibits proliferation and stimulates ecto-5′-nucleotidase/CD73 activity in C6 rat glioma cell line
inferredcites →https://doi.org/10.1016/0006-3223(90)90368-copenalex-snapshot
A longitudinal evaluation of dexamethasone pharmacokinetics in depressed patients and normal controls
inferredcites →https://doi.org/10.1016/j.bbrc.2008.07.149openalex-snapshot
Dexamethasone down-regulates ABCG2 expression levels in breast cancer cells
inferredcites →https://doi.org/10.1016/j.drudis.2007.10.002openalex-snapshot
The role of mechanism-based pharmacokinetic–pharmacodynamic (PK–PD) modelling in translational research of biologics
inferredcites →https://doi.org/10.1016/j.ejphar.2008.06.111openalex-snapshot
Dexamethasone reduced invasiveness of human malignant glioblastoma cells through a MAPK phosphatase-1 (MKP-1) dependent mechanism
inferredcites →https://doi.org/10.1016/s0006-2952(97)00166-4openalex-snapshot
In vitro metabolism of dexamethasone (DEX) in human liver and kidney: The involvement of CYP3a4 and CYP17 (17,20 LYASE) and molecular modelling studies
inferredcites →https://doi.org/10.1038/aps.2011.161openalex-snapshot
A mechanism-based pharmacokinetic/pharmacodynamic model for CYP3A1/2 induction by dexamethasone in rats
inferredcites →https://doi.org/10.1038/aps.2016.39openalex-snapshot
Dexamethasone suppresses the growth of human non-small cell lung cancer via inducing estrogen sulfotransferase and inactivating estrogen
inferredcites →https://doi.org/10.1038/aps.2016.55openalex-snapshot
Preclinical PK/PD model for combined administration of erlotinib and sunitinib in the treatment of A549 human NSCLC xenograft mice
inferredcites →https://doi.org/10.1038/aps.2017.24openalex-snapshot
Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer
inferredcites →https://doi.org/10.1097/00004714-199206000-00008openalex-snapshot
A Longitudinal Evaluation of
inferredcites →https://doi.org/10.1111/bcp.12427openalex-snapshot
Vatalanib population pharmacokinetics in patients with myelodysplastic syndrome: CALGB 10105 ( A lliance)
inferredcites →https://doi.org/10.1111/j.1365-2125.2007.03095.xopenalex-snapshot
Population pharmacokinetics and exploratory pharmacodynamics of ifosfamide according to continuous or short infusion schedules: an n = 1 randomized study
inferredcites →https://doi.org/10.1158/0008-5472.can-03-2524openalex-snapshot
Predictive Pharmacokinetic-Pharmacodynamic Modeling of Tumor Growth Kinetics in Xenograft Models after Administration of Anticancer Agents
inferredcites →https://doi.org/10.1158/0008-5472.can-08-1545openalex-snapshot
Glucocorticoids Antagonize Estrogens by Glucocorticoid Receptor–Mediated Activation of Estrogen Sulfotransferase
inferredcites →https://doi.org/10.1517/17425255.2012.693480openalex-snapshot
Mathematical modeling of tumor growth and tumor growth inhibition in oncology drug development
inferredcites →https://doi.org/10.2165/0003088-200847120-00005openalex-snapshot
A Mechanism-Based Population Pharmacokinetic Model for Characterizing Time-Dependent Pharmacokinetics of Midostaurin and its Metabolites in Human Subjects
inferredcites →https://doi.org/10.3109/00498254.2012.761741openalex-snapshot
Time-dependent changes in hepatic and intestinal induction of cytochrome P450 3A after administration of dexamethasone to rats
inferredcites →https://doi.org/10.3892/ijo.30.4.947openalex-snapshot
Dexamethasone as a chemosensitizer for breast cancer chemotherapy: Potentiation of the antitumor activity of adriamycin, modulation of cytokine expression, and pharmacokinetics
inferredcites →https://doi.org/10.4161/cbt.7.7.6099openalex-snapshot
Dexamethasone reduces tumor recurrence and metastasis after pancreatic tumor resection in SCID mice
inferredcites →https://doi.org/10.6004/jnccn.2016.0037openalex-snapshot
Invasive Breast Cancer Version 1.2016, NCCN Clinical Practice Guidelines in Oncology
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Baeyer-Villiger Monooxygenases Using the FMO5 for the Detoxification of Testosterone and Dehydroepiandrosterone in LNCaP Cells
inferred← citeshttps://doi.org/10.1007/s43450-022-00265-7openalex-snapshot
Pharmacokinetic-Pharmacodynamic Modeling of Active Components from Salvia miltiorrhiza (Danshen) and Carthamus tinctorius (Honghua) in Focal Cerebral Ischemia Rats
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2022.103625openalex-snapshot
Advantages and drawbacks of dexamethasone in glioblastoma multiforme
inferred← citeshttps://doi.org/10.1016/j.eurpolymj.2026.114820openalex-snapshot
1,10-Phenanthroline complexes of zinc as highly active biocompatible catalysts in cyclic oxalates polymerization displaying unique regioselectivity
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.125282openalex-snapshot
Glucocorticoid pre-administration improves LNP-mRNA mediated protein replacement and genome editing therapies
inferred← citeshttps://doi.org/10.1016/j.ijrobp.2021.04.021openalex-snapshot
Coadministration of a Clinically Relevant Dexamethasone Dosage With Ablative Radiation Therapy Reduces Peripheral Lymphocytes But Does Not Alter In Vivo Intratumoral Lymphocyte Phenotype or Inhibit Efficacy of Radiation Therapy in a Murine Colorectal Tumor Model
inferred← citeshttps://doi.org/10.1016/j.microc.2021.106329openalex-snapshot
Employ FTIR spectroscopic method for determination of certain multiple sclerosis medications in plasma and pharmaceutical formulations
inferred← citeshttps://doi.org/10.1016/j.resp.2019.103283openalex-snapshot
Glucocorticoids inhibits the repair of airway epithelial cells via the activation of wnt pathway
inferred← citeshttps://doi.org/10.1016/j.xphs.2019.10.035openalex-snapshot
Pharmacokinetic/Pharmacodynamic Modeling of the Anti-Cancer Effect of Dexamethasone in Pancreatic Cancer Xenografts and Anticipation of Human Efficacious Doses
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.0c01203openalex-snapshot
Enhancing the Therapeutic Efficacy of Gefitinib in Human Non-Small-Cell Lung Cancer through Drug Combination
inferred← citeshttps://doi.org/10.1038/s41401-019-0251-7openalex-snapshot
Preclinical PK/PD model for the combinatorial use of dexamethasone and sulpiride in the treatment of breast cancer
inferred← citeshttps://doi.org/10.1080/16078454.2021.2009643openalex-snapshot
PON2 blockade overcomes dexamethasone resistance in acute lymphoblastic leukemia
inferred← citeshttps://doi.org/10.1093/jac/dkab094openalex-snapshot
A combined assay for quantifying remdesivir and its metabolite, along with dexamethasone, in serum
inferred← citeshttps://doi.org/10.1093/mutage/geac009openalex-snapshot
A novel in vitro 3D model of the human bone marrow to bridge the gap between in vitro and in vivo genotoxicity testing
inferred← citeshttps://doi.org/10.1371/journal.pone.0258579openalex-snapshot
Vitamin D levels do not cause vitamin-drug interactions with dexamethasone or dasatinib in mice
inferred← citeshttps://doi.org/10.21007/etd.cghs.2020.0523openalex-snapshot
Vitamin D Levels Affect Survival in a BCR-ABL Acute Lymphoblastic Leukemia Mouse Model but Do Not Cause Vitamin-Drug Interactions
inferred← citeshttps://doi.org/10.3390/cancers14205071openalex-snapshot
Chronotherapy: Circadian Rhythms and Their Influence in Cancer Therapy
inferred← citeshttps://doi.org/10.3390/cimb46030153openalex-snapshot
Deciphering Glioblastoma: Fundamental and Novel Insights into the Biology and Therapeutic Strategies of Gliomas
inferred← citeshttps://doi.org/10.3390/pharmaceutics11090479openalex-snapshot
Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators
inferred← citeshttps://doi.org/10.3390/pharmaceutics12100975openalex-snapshot
Physiologically-Based Pharmacokinetic/Pharmacodynamic Model of MBQ-167 to Predict Tumor Growth Inhibition in Mice
inferred← citeshttps://doi.org/10.3390/toxics11070581openalex-snapshot
Time- and Concentration-Dependent Adverse Effects of Paclitaxel on Non-Neuronal Cells in Rat Primary Dorsal Root Ganglia
inferred← citeshttps://doi.org/10.5306/wjco.v15.i7.818openalex-snapshot
Circadian rhythm disruption and endocrine-related tumors
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