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Nrf2-dependent persistent oxidative stress results in stress-induced vulnerability to depression

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ana.10483openalex-snapshot
Oxidative stress in Parkinson's disease
inferredcites →https://doi.org/10.1002/ana.24414openalex-snapshot
Predicting and treating stress‐Induced vulnerability to epilepsy and depression
inferredcites →https://doi.org/10.1007/s00204-011-0674-5openalex-snapshot
The cytoprotective role of the Keap1–Nrf2 pathway
inferredcites →https://doi.org/10.1007/s00406-011-0189-3openalex-snapshot
BDNF serum levels, but not BDNF Val66Met genotype, are correlated with personality traits in healthy subjects
inferredcites →https://doi.org/10.1007/s00432-014-1627-1openalex-snapshot
Nrf2: bane or blessing in cancer?
inferredcites →https://doi.org/10.1007/s10059-009-0050-yopenalex-snapshot
Transcriptional Regulation of the AP-1 and Nrf2 Target Gene Sulfiredoxin
inferredcites →https://doi.org/10.1007/s10519-011-9462-5openalex-snapshot
Gene Expression in Aminergic and Peptidergic Cells During Aggression and Defeat: Relevance to Violence, Depression and Drug Abuse
inferredcites →https://doi.org/10.1007/s10787-011-0111-7openalex-snapshot
New drug targets in depression: inflammatory, cell-mediated immune, oxidative and nitrosative stress, mitochondrial, antioxidant, and neuroprogressive pathways. And new drug candidates—Nrf2 activators and GSK-3 inhibitors
inferredcites →https://doi.org/10.1007/s11064-010-0310-4openalex-snapshot
Phenylarsine Oxide Binding Reveals Redox-Active and Potential Regulatory Vicinal Thiols on the Catalytic Subunit of Protein Phosphatase 2A
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Adverse Stress, Hippocampal Networks, and Alzheimer’s Disease
inferredcites →https://doi.org/10.1007/s12031-012-9899-xopenalex-snapshot
Protective Effects of 7,8-Dihydroxyflavone on Retinal Ganglion and RGC-5 Cells Against Excitotoxic and Oxidative Stress
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Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons
inferredcites →https://doi.org/10.1016/j.biopsych.2008.11.028openalex-snapshot
Lasting Epigenetic Influence of Early-Life Adversity on the BDNF Gene
inferredcites →https://doi.org/10.1016/j.cell.2007.09.018openalex-snapshot
Molecular Adaptations Underlying Susceptibility and Resistance to Social Defeat in Brain Reward Regions
inferredcites →https://doi.org/10.1016/j.conb.2009.05.001openalex-snapshot
Redox dysregulation, neurodevelopment, and schizophrenia
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2011.03.039openalex-snapshot
Nitric oxide activates an Nrf2/sulfiredoxin antioxidant pathway in macrophages
inferredcites →https://doi.org/10.1016/j.jpsychires.2011.03.002openalex-snapshot
Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis
inferredcites →https://doi.org/10.1016/j.metabol.2014.10.029openalex-snapshot
Biomarkers for assessing population and individual health and disease related to stress and adaptation
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Environmental and pharmacological modulations of cellular plasticity: Role in the pathophysiology and treatment of depression
inferredcites →https://doi.org/10.1016/j.neulet.2011.05.054openalex-snapshot
Antioxidant activity of 7,8-dihydroxyflavone provides neuroprotection against glutamate-induced toxicity
inferredcites →https://doi.org/10.1016/j.neures.2010.08.007openalex-snapshot
Oxidative stress in anxiety and comorbid disorders
inferredcites →https://doi.org/10.1016/j.pharmthera.2010.01.003openalex-snapshot
Effects of tempol and redox-cycling nitroxides in models of oxidative stress
inferredcites →https://doi.org/10.1016/j.psyneuen.2013.03.020openalex-snapshot
Nrf2 participates in depressive disorders through an anti-inflammatory mechanism
inferredcites →https://doi.org/10.1016/s0021-9258(18)41538-4openalex-snapshot
The inactivation of Fe-S cluster containing hydro-lyases by superoxide.
inferredcites →https://doi.org/10.1016/s0300-483x(00)00306-1openalex-snapshot
Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology
inferredcites →https://doi.org/10.1016/s0361-9230(03)00179-5openalex-snapshot
Neurodegeneration in amyotrophic lateral sclerosis: the role of oxidative stress and altered homeostasis of metals
inferredcites →https://doi.org/10.1016/s1383-5742(97)00035-5openalex-snapshot
Analysis of a form of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis
inferredcites →https://doi.org/10.1023/a:1025766415159openalex-snapshot
Individual Variation in Aggression of Feral Rodent Strains: A Standard for the Genetics of Aggression and Violence?
inferredcites →https://doi.org/10.1038/cddis.2010.68openalex-snapshot
Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease
inferredcites →https://doi.org/10.1038/nature02075openalex-snapshot
ATP-dependent reduction of cysteine–sulphinic acid by S. cerevisiae sulphiredoxin
inferredcites →https://doi.org/10.1038/nature07455openalex-snapshot
The molecular neurobiology of depression
inferredcites →https://doi.org/10.1038/nm.3090openalex-snapshot
Epigenetic regulation of RAC1 induces synaptic remodeling in stress disorders and depression
inferredcites →https://doi.org/10.1038/nm0807-907openalex-snapshot
Peroxiredoxin-2 links Cdk5 to neurodegeneration
inferredcites →https://doi.org/10.1038/npp.2010.114openalex-snapshot
Peripheral BDNF Produces Antidepressant-Like Effects in Cellular and Behavioral Models
inferredcites →https://doi.org/10.1038/nprot.2012.035openalex-snapshot
Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila
inferredcites →https://doi.org/10.1038/nrn1683openalex-snapshot
Stress and the brain: from adaptation to disease
inferredcites →https://doi.org/10.1038/sj.mp.4002097openalex-snapshot
Repeated social defeat-induced depression-like behavioral and biological alterations in rats: involvement of cholecystokinin
inferredcites →https://doi.org/10.1038/sj.npp.1300382openalex-snapshot
BDNF Serum Concentrations in Healthy Volunteers are Associated with Depression-Related Personality Traits
inferredcites →https://doi.org/10.1046/j.1471-4159.2002.01103.xopenalex-snapshot
Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase‐related protein 2, α‐enolase and heat shock cognate 71
inferredcites →https://doi.org/10.1055/s-0029-1224162openalex-snapshot
Correlations and Discrepancies between Serum and Brain Tissue Levels of Neurotrophins after Electroconvulsive Treatment in Rats
inferredcites →https://doi.org/10.1073/pnas.0913572107openalex-snapshot
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone
inferredcites →https://doi.org/10.1074/jbc.r111.283432openalex-snapshot
Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides
inferredcites →https://doi.org/10.1083/jcb.200606005openalex-snapshot
Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery
inferredcites →https://doi.org/10.1089/ars.2010.3567openalex-snapshot
CNS Peroxiredoxins and Their Regulation in Health and Disease
inferredcites →https://doi.org/10.1093/bioinformatics/bth456openalex-snapshot
GO::TermFinder—open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes
inferredcites →https://doi.org/10.1096/fj.04-3084fjeopenalex-snapshot
Differential proteome analysis of aging in rat skeletal muscle
inferredcites →https://doi.org/10.1096/fj.11-0502ufmopenalex-snapshot
The resolution of inflammation: the devil in the flask and in the details
inferredcites →https://doi.org/10.1097/psy.0b013e3182306a4fopenalex-snapshot
Neuroticism, Depressive Symptoms, and Serum BDNF
inferredcites →https://doi.org/10.1101/gad.13.1.76openalex-snapshot
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
inferredcites →https://doi.org/10.1111/j.1471-4159.1992.tb09344.xopenalex-snapshot
Opioid Control of the In Vitro Release of Cholecystokinin‐Like Material from the Rat Substantia Nigra
inferredcites →https://doi.org/10.1111/j.1471-4159.2006.03907.xopenalex-snapshot
Oxidative stress and neurodegeneration: where are we now?
inferredcites →https://doi.org/10.1111/j.1749-6632.2010.05568.xopenalex-snapshot
Stress, sex, and neural adaptation to a changing environment: mechanisms of neuronal remodeling
inferredcites →https://doi.org/10.1124/pr.108.000240openalex-snapshot
Chemistry and Antihypertensive Effects of Tempol and Other Nitroxides
inferredcites →https://doi.org/10.1126/science.1130481openalex-snapshot
H 2 O 2 , a Necessary Evil for Cell Signaling
inferredcites →https://doi.org/10.1159/000350094openalex-snapshot
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
inferredcites →https://doi.org/10.1159/000373980openalex-snapshot
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
inferredcites →https://doi.org/10.1161/01.hyp.0000142232.29764.a7openalex-snapshot
Modulation of Oxidant and Antioxidant Enzyme Expression and Function in Vascular Cells
inferredcites →https://doi.org/10.1161/hypertensionaha.111.184218openalex-snapshot
Tempol Prevents Altered K + Channel Regulation of Afferent Arteriolar Tone in Diabetic Rat Kidney
inferredcites →https://doi.org/10.1177/1534582306289043openalex-snapshot
What Is the Functional Significance of Chronic Stress-Induced CA3 Dendritic Retraction Within the Hippocampus?
inferredcites →https://doi.org/10.1177/1745691613506907openalex-snapshot
The Brain on Stress
inferredcites →https://doi.org/10.1248/bpb.32.166openalex-snapshot
Preventive Effect of 7,8-Dihydroxyflavone against Oxidative Stress Induced Genotoxicity
inferredcites →https://doi.org/10.1523/jneurosci.0743-05.2005openalex-snapshot
Involvement of Cholecystokininergic Systems in Anxiety-Induced Hyperalgesia in Male Rats: Behavioral and Biochemical Studies
inferredcites →https://doi.org/10.1523/jneurosci.1309-11.2011openalex-snapshot
Vulnerability to Depression: From Brain Neuroplasticity to Identification of Biomarkers
inferredcites →https://doi.org/10.1523/jneurosci.21-01-00262.2001openalex-snapshot
Enhanced Cortical Extracellular Levels of Cholecystokinin-Like Material in a Model of Anticipation of Social Defeat in the Rat
inferredcites →https://doi.org/10.1523/jneurosci.4014-05.2005openalex-snapshot
A Small-Molecule-Inducible Nrf2-Mediated Antioxidant Response Provides Effective Prophylaxis against Cerebral IschemiaIn Vivo
inferredcites →https://doi.org/10.2174/1381612043384664openalex-snapshot
Oxygen, Reactive Oxygen Species and Tissue Damage
inferredcites →https://doi.org/10.2174/1568007054038238openalex-snapshot
The Nrf2-ARE Signalling Pathway: Promising Drug Target to Combat Oxidative Stress in Neurodegenerative Disorders
inferredcites →https://doi.org/10.3109/00207450108986514openalex-snapshot
Motor Impairments in an Oxidative Stress Model and its Correlation with Cytological Changes on Rat Striatum and Prefrontal Cortex
inferredcites →https://doi.org/10.3109/10715762.2010.507670openalex-snapshot
Nrf2-ARE stress response mechanism: A control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
inferred← citeshttps://doi.org/10.1002/jbt.23398openalex-snapshot
Neferine protected cardiomyocytes against hypoxia/oxygenation injury through SIRT1/Nrf2/HO‐1 signaling
inferred← citeshttps://doi.org/10.1002/jbt.70473openalex-snapshot
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The Hypoxia Response Pathway: A Potential Intervention Target in Parkinson's Disease?
inferred← citeshttps://doi.org/10.1007/978-3-030-52663-4_28openalex-snapshot
Hormesis, Resilience and Mental Health: Enhancing Public Health and Therapeutic Options
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Redox metabolism modulation as a mechanism in SSRI toxicity and pharmacological effects
inferred← citeshttps://doi.org/10.1007/s00204-023-03660-8openalex-snapshot
Ferroptosis regulation through Nrf2 and implications for neurodegenerative diseases
inferred← citeshttps://doi.org/10.1007/s00213-018-4949-xopenalex-snapshot
Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways
inferred← citeshttps://doi.org/10.1007/s00213-020-05502-2openalex-snapshot
7,8-Dihydroxyflavone alleviated the high-fat diet and alcohol-induced memory impairment: behavioral, biochemical and molecular evidence
inferred← citeshttps://doi.org/10.1007/s00213-021-05853-4openalex-snapshot
Co-treatment of vitamin D supplementation with enriched environment improves synaptic plasticity and spatial learning and memory in aged rats
inferred← citeshttps://doi.org/10.1007/s00213-022-06140-6openalex-snapshot
Altered responsiveness of the antioxidant system in chronically stressed animals: modulation by chronic lurasidone treatment
inferred← citeshttps://doi.org/10.1007/s00406-017-0848-0openalex-snapshot
Keap1–Nrf2 signaling pathway confers resilience versus susceptibility to inescapable electric stress
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Behavioral changes during social ascent and descent in replicate social networks of an African cichlid fish
inferred← citeshttps://doi.org/10.1007/s10787-022-01004-zopenalex-snapshot
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Peritoneal endometriosis induces time-related depressive- and anxiety-like alterations in female rats: involvement of hippocampal pro-oxidative and BDNF alterations
inferred← citeshttps://doi.org/10.1007/s11011-022-01019-zopenalex-snapshot
Schisandra chinensis (Turcz.) Baill. essential oil exhibits antidepressant-like effects and against brain oxidative stress through Nrf2/HO-1 pathway activation
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TCE-mediated neuroprotection against rotenone-induced dopaminergic neuronal death in PD mice: insights into the Nrf-2/PINK1/Parkin-mitophagy pathway
inferred← citeshttps://doi.org/10.1007/s11064-021-03396-wopenalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s11064-022-03707-9openalex-snapshot
Effect of Epigallocatechin-3-gallate on Stress-Induced Depression in a Mouse Model: Role of Interleukin-1β and Brain-Derived Neurotrophic Factor
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inferred← citeshttps://doi.org/10.1007/s12031-020-01664-yopenalex-snapshot
Naringin Confers Protection against Psychosocial Defeat Stress-Induced Neurobehavioral Deficits in Mice: Involvement of Glutamic Acid Decarboxylase Isoform-67, Oxido-Nitrergic Stress, and Neuroinflammatory Mechanisms
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Etomidate Improves the Antidepressant Effect of Electroconvulsive Therapy by Suppressing Hippocampal Neuronal Ferroptosis via Upregulating BDNF/Nrf2
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Identification of Potential Biomarkers for Major Depressive Disorder: Based on Integrated Bioinformatics and Clinical Validation
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Oxidative Stress in Treatment-Resistant and Refractory Depression: A Hidden Therapeutic Target?
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Peripheral Administration of Tetanus Toxin Hc Fragment Prevents MPP+ Toxicity In Vivo
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The gut microbiome
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Chronic stress increases transcriptomic indicators of biological aging in mouse bone marrow leukocytes
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Nrf2 deletion results in impaired performance in memory tasks and hyperactivity in mature and aged mice
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BDNF as potential biomarker of epilepsy severity and psychiatric comorbidity: pitfalls in the clinical population
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P2Y6 receptor blockade promotes depression-like symptoms through oxidative stress and impaired autophagy
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SIRT1-mediated regulation of inflammation and keratinocyte function in psoriasis
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An AOP-informed Bayesian network framework for identifying candidate safer physicochemical domains in per- and polyfluoroalkyl substances-induced developmental neurotoxicity
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inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110520openalex-snapshot
Potential anxiolytic and antidepressant-like effects of luteolin in a chronic constriction injury rat model of neuropathic pain: Role of oxidative stress, neurotrophins, and inflammatory factors
inferred← citeshttps://doi.org/10.1016/j.jad.2020.07.108openalex-snapshot
Skin autofluorescence of advanced glycation end products and course of affective disorders in the lifelines cohort study, a prospective investigation
inferred← citeshttps://doi.org/10.1016/j.jad.2022.06.003openalex-snapshot
Association of mood disorder with cardiometabolic multimorbidity trajectory and life expectancy, a prospective cohort study
inferred← citeshttps://doi.org/10.1016/j.jad.2022.12.092openalex-snapshot
Social isolation after chronic unpredictable mild stress perpetuates depressive-like behaviors, memory deficits and social withdrawal via inhibiting ERK/KEAP1/NRF2 signaling
inferred← citeshttps://doi.org/10.1016/j.jff.2021.104657openalex-snapshot
Holothuria leucospilota polysaccharides alleviate liver injury via AMPK and NF-κB signaling pathways in type 2 diabetic rats
inferred← citeshttps://doi.org/10.1016/j.jff.2022.105305openalex-snapshot
A20, as a downstream factor of Nrf2, is involved in the anti-neuroinflammatory and antidepressant-like effects of luteolin
inferred← citeshttps://doi.org/10.1016/j.joca.2023.05.004openalex-snapshot
Age and oxidative stress regulate Nrf2 homeostasis in human articular chondrocytes
inferred← citeshttps://doi.org/10.1016/j.jpsychires.2021.10.021openalex-snapshot
Lipopolysaccharide exacerbates chronic restraint stress-induced neurobehavioral deficits: Mechanisms by redox imbalance, ASK1-related apoptosis, autophagic dysregulation
inferred← citeshttps://doi.org/10.1016/j.jpsychires.2024.09.008openalex-snapshot
Level of selected exponents of the kynurenine pathway in patients diagnosed with depression and selected cancers
inferred← citeshttps://doi.org/10.1016/j.lfs.2023.122004openalex-snapshot
Niacin modulates depressive-like behavior in experimental colitis through GPR109A-dependent mechanisms
inferred← citeshttps://doi.org/10.1016/j.lfs.2023.122045openalex-snapshot
Intrathecal umbilical cord mesenchymal stem cells injection alleviates neuroinflammation and oxidative stress in the cyclophosphamide-induced interstitial cystitis rats through the Sirt1/Nrf2/HO-1 pathway
inferred← citeshttps://doi.org/10.1016/j.mehy.2020.110398openalex-snapshot
Elevating the level of hypoxia inducible factor may be a new potential target for the treatment of depression
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2020.03.015openalex-snapshot
Therapeutic potential of glutathione-enhancers in stress-related psychopathologies
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2020.10.011openalex-snapshot
Stress and coping in women with breast cancer:unravelling the mechanisms to improve resilience
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2025.106393openalex-snapshot
Relationships between adverse childhood experiences, oxidative stress, and development of mental disorders: A systematic review of animal and human studies
inferred← citeshttps://doi.org/10.1016/j.neuint.2021.105269openalex-snapshot
Importance of oxidative stress in the pathogenesis, diagnosis, and monitoring of patients with neuropsychiatric disorders, a review
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2020.108235openalex-snapshot
Sulforaphane alleviates ethanol-mediated central inhibition and reverses chronic stress-induced aggravation of acute alcoholism via targeting Nrf2-regulated catalase expression
inferred← citeshttps://doi.org/10.1016/j.neuropharm.2022.109169openalex-snapshot
Kynurenine monooxygenase inhibition and associated reduced quinolinic acid reverses depression-like behaviour by upregulating Nrf2/ARE pathway in mouse model of depression: In-vivo and In-silico studies
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2021.07.029openalex-snapshot
Catalpol Weakens Depressive-like Behavior in Mice with Streptozotocin-induced Hyperglycemia via PI3K/AKT/Nrf2/HO-1 Signaling Pathway
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2020.107520openalex-snapshot
Oxidation-reduction mechanisms in psychiatric disorders: A novel target for pharmacological intervention
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.105330openalex-snapshot
Behavioral and molecular effects of the antipsychotic drug blonanserin in the chronic mild stress model
inferred← citeshttps://doi.org/10.1016/j.phrs.2022.106099openalex-snapshot
Targeting Akt/CREB/BDNF signaling pathway by ginsenosides in neurodegenerative diseases: A mechanistic approach
inferred← citeshttps://doi.org/10.1016/j.phymed.2021.153598openalex-snapshot
The triterpenoid ursolic acid ameliorates stress in Caenorhabditis elegans by affecting the depression-associated genes skn-1 and prdx2
inferred← citeshttps://doi.org/10.1016/j.pneurobio.2023.102405openalex-snapshot
Activation of Neuronal FLT3 Promotes Exaggerated Sensorial and Emotional Pain-Related Behaviors Facilitating the Transition from Acute to Chronic Pain
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2020.109956openalex-snapshot
Insights into serotonergic and antioxidant mechanisms involved in antidepressant-like action of 2-phenyl-3-(phenylselanyl)benzofuran in mice
inferred← citeshttps://doi.org/10.1016/j.psychres.2020.112782openalex-snapshot
Inflammatory and antioxidant pathway dysfunction in borderline personality disorder
inferred← citeshttps://doi.org/10.1016/j.redox.2020.101475openalex-snapshot
Redox toxicology of environmental chemicals causing oxidative stress
inferred← citeshttps://doi.org/10.1016/j.redox.2022.102354openalex-snapshot
High frequency repetitive transcranial magnetic stimulation alleviates cognitive deficits in 3xTg-AD mice by modulating the PI3K/Akt/GLT-1 axis
inferred← citeshttps://doi.org/10.1016/j.redox.2022.102522openalex-snapshot
Nrf2: An all-rounder in depression
inferred← citeshttps://doi.org/10.1016/j.redox.2024.103464openalex-snapshot
Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases
inferred← citeshttps://doi.org/10.1016/j.redox.2025.103617openalex-snapshot
Effects of Omega-3 PUFAs on lipid profiles and antioxidant response in depressed adolescents: A metabolomic and lipidomic study
inferred← citeshttps://doi.org/10.1016/j.redox.2025.103620openalex-snapshot
Design of anti-depressant phosphodiester amino acidic Keap1-Nrf2 protein-protein interaction inhibitors
inferred← citeshttps://doi.org/10.1016/j.toxlet.2020.04.017openalex-snapshot
Recent advances in understanding the mechanisms of PM2.5-mediated neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.yebeh.2017.09.014openalex-snapshot
Epilepsy as a Network Disorder (1): What can we learn from other network disorders such as autistic spectrum disorder and mood disorders?
inferred← citeshttps://doi.org/10.1016/j.yfrne.2019.100783openalex-snapshot
Individual differences in inflammatory and oxidative mechanisms of stress-related mood disorders
inferred← citeshttps://doi.org/10.1016/j.ynstr.2020.100245openalex-snapshot
Social defeat: Vagal reduction and vulnerability to ventricular arrhythmias
inferred← citeshttps://doi.org/10.1016/j.ynstr.2023.100569openalex-snapshot
Time-course analysis of frontal gene expression profiles in the rat model of posttraumatic stress disorder and a comparison with the conditioned fear model
inferred← citeshttps://doi.org/10.1016/s1875-5364(26)61211-3openalex-snapshot
From bench to beside: luteolin's therapeutic promise in neurological disorders
inferred← citeshttps://doi.org/10.1021/envhealth.6c00099openalex-snapshot
Exposure to Ambient Fine Particulate Matter (PM2.5) Increases Vulnerability to Stress-Induced Depression in Mice, Potentially via the BDNF-CREB Signaling Pathway
inferred← citeshttps://doi.org/10.1038/mp.2017.47openalex-snapshot
Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia
inferred← citeshttps://doi.org/10.1038/s41380-026-03656-7openalex-snapshot
Sex-specific regulation of angiogenin in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1038/s41386-021-01144-wopenalex-snapshot
α2-containing γ-aminobutyric acid type A receptors promote stress resiliency in male mice
inferred← citeshttps://doi.org/10.1038/s41398-021-01261-6openalex-snapshot
Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents
inferred← citeshttps://doi.org/10.1038/s41398-022-02183-7openalex-snapshot
Time of exposure to social defeat stress during childhood and adolescence and redox dysregulation on long-lasting behavioral changes, a translational study
inferred← citeshttps://doi.org/10.1038/s41398-023-02322-8openalex-snapshot
Low protein-induced intrauterine growth restriction as a risk factor for schizophrenia phenotype in a rat model: assessing the role of oxidative stress and neuroinflammation interaction
inferred← citeshttps://doi.org/10.1038/s41398-023-02701-1openalex-snapshot
Bdnf-Nrf-2 crosstalk and emotional behavior are disrupted in a sex-dependent fashion in adolescent mice exposed to maternal stress or maternal obesity
inferred← citeshttps://doi.org/10.1038/s41398-023-02728-4openalex-snapshot
Sex-specific interactions between stress axis and redox balance are associated with internalizing symptoms and brain white matter microstructure in adolescents
inferred← citeshttps://doi.org/10.1038/s41401-019-0238-4openalex-snapshot
Curculigoside facilitates fear extinction and prevents depression-like behaviors in a mouse learned helplessness model through increasing hippocampal BDNF
inferred← citeshttps://doi.org/10.1038/s41401-021-00727-zopenalex-snapshot
Sulforaphane activates anti-inflammatory microglia, modulating stress resilience associated with BDNF transcription
inferred← citeshttps://doi.org/10.1038/s41420-022-01063-9openalex-snapshot
Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity
inferred← citeshttps://doi.org/10.1038/s41598-017-10443-6openalex-snapshot
The Chinese herbal formula Free and Easy Wanderer ameliorates oxidative stress through KEAP1-NRF2/HO-1 pathway
inferred← citeshttps://doi.org/10.1038/s41598-023-45045-yopenalex-snapshot
BDNF-loaded PDADMAC-heparin multilayers: a novel approach for neuroblastoma cell study
inferred← citeshttps://doi.org/10.1038/s41598-026-63912-2openalex-snapshot
Integrated biomarkers of oxidative stress NLRP3 inflammasome and kynurenine pathway reflect disease severity and diagnostic discrimination in depression
inferred← citeshttps://doi.org/10.1039/d1fo00210dopenalex-snapshot
Hydroxytyrosol alleviates oxidative stress and neuroinflammation and enhances hippocampal neurotrophic signaling to improve stress-induced depressive behaviors in mice
inferred← citeshttps://doi.org/10.1039/d1fo02385copenalex-snapshot
Food-derived cyanidin-3- O -glucoside alleviates oxidative stress: evidence from the islet cell line and diabetic db/db mice
inferred← citeshttps://doi.org/10.1039/d2fo01437hopenalex-snapshot
Soy isoflavones alleviate lipopolysaccharide-induced depressive-like behavior by suppressing neuroinflammation, mediating tryptophan metabolism and promoting synaptic plasticity
inferred← citeshttps://doi.org/10.1039/d2fo03708dopenalex-snapshot
Study on Lactiplantibacillus plantarum R6-3 from Sayram Ketteki to prevent chronic unpredictable mild stress-induced depression in mice through the microbiota–gut–brain axis
inferred← citeshttps://doi.org/10.1042/cs20160982openalex-snapshot
Diminished stress resistance and defective adaptive homeostasis in age-related diseases
inferred← citeshttps://doi.org/10.1055/a-2437-1751openalex-snapshot
ABC Family Gene Polymorphisms and Cognitive Functions Interact to Influence Antidepressant Efficacy
inferred← citeshttps://doi.org/10.1080/00439339.2022.2094845openalex-snapshot
Advances in epigenetic mechanisms of chick embryo heat acclimation
inferred← citeshttps://doi.org/10.1080/08923973.2021.1879847openalex-snapshot
Schizandrin ameliorates behavioral disorders in hepatic injury mice via regulation of oxidative stress and neuroinflammation
inferred← citeshttps://doi.org/10.1080/14728222.2021.1887141openalex-snapshot
The Nrf2 pathway in psychiatric disorders: pathophysiological role and potential targeting
inferred← citeshttps://doi.org/10.1093/cercor/bhy164openalex-snapshot
Methylphenidate Attenuates the Cognitive and Mood Alterations Observed inMbnl2Knockout Mice and Reduces Microglia Overexpression
inferred← citeshttps://doi.org/10.1093/ijnp/pyy046openalex-snapshot
Chronic Stress Exposure Reduces Parvalbumin Expression in the Rat Hippocampus through an Imbalance of Redox Mechanisms: Restorative Effect of the Antipsychotic Lurasidone
inferred← citeshttps://doi.org/10.1093/ijnp/pyz052openalex-snapshot
Naturally Derived Polyphenols Protect Against Corticosterone-Induced Changes in Primary Cortical Neurons
inferred← citeshttps://doi.org/10.1093/sleep/zsad117openalex-snapshot
Exploring non-rapid eye movement sleep substages in rats to develop biomarkers for depression
inferred← citeshttps://doi.org/10.1093/toxsci/kfab149openalex-snapshot
The Exposome and Toxicology: A Win–Win Collaboration
inferred← citeshttps://doi.org/10.1097/fbp.0000000000000477openalex-snapshot
The ‘Yin’ and the ‘Yang’ of the kynurenine pathway: excitotoxicity and neuroprotection imbalance in stress-induced disorders
inferred← citeshttps://doi.org/10.1101/2022.08.23.504973openalex-snapshot
A receptor-independent signaling pathway for BDNF
inferred← citeshttps://doi.org/10.1111/cbdd.14626openalex-snapshot
NMC ‐4 Ameliorates Depression‐Like Behavior and Neuroinflammation Caused by Chronic Unpredictable Mild Stress
inferred← citeshttps://doi.org/10.1111/cns.14265openalex-snapshot
Ferulic acid as a therapeutic agent in depression: Evidence from preclinical studies
inferred← citeshttps://doi.org/10.1111/epi.14692openalex-snapshot
Antioxidant treatment after epileptogenesis onset prevents comorbidities in rats sensitized by a past stressful event
inferred← citeshttps://doi.org/10.1111/jnc.14476openalex-snapshot
Astrocyte truncated tropomyosin receptor kinase B mediates brain‐derived neurotrophic factor anti‐apoptotic effect leading to neuroprotection
inferred← citeshttps://doi.org/10.1111/joor.13536openalex-snapshot
Is burning mouth syndrome associated with stress? A meta‐analysis
inferred← citeshttps://doi.org/10.1111/joor.13964openalex-snapshot
The Role of Stress in Burning Mouth Syndrome Triggered by Dental Treatments: A Two‐Step Hypothesis
inferred← citeshttps://doi.org/10.1113/ep087122openalex-snapshot
Ischaemic and hypoxic conditioning: potential for protection of vital organs
inferred← citeshttps://doi.org/10.1134/s1990519x21040088openalex-snapshot
The Effect of Blockade of Androgen Receptors by Flutamide on Learning and Memory, Synaptic Plasticity and Behavioral Performances: A Review Study
inferred← citeshttps://doi.org/10.1136/gpsych-2022-100910openalex-snapshot
Disturbed sensitive equilibrium led by stress‐induced inflammation in psychiatric illness
inferred← citeshttps://doi.org/10.1146/annurev-marine-040821-075606openalex-snapshot
The Biological Effects of Pharmaceuticals in the Marine Environment
inferred← citeshttps://doi.org/10.1155/2018/6069150openalex-snapshot
Uric Acid Protects against Focal Cerebral Ischemia/Reperfusion‐Induced Oxidative Stress via Activating Nrf2 and Regulating Neurotrophic Factor Expression
inferred← citeshttps://doi.org/10.1155/2018/9516592openalex-snapshot
Translational Significance of Selective Estrogen Receptor Modulators in Psychiatric Disorders
inferred← citeshttps://doi.org/10.1155/2020/2972968openalex-snapshot
Targeting Inflammatory-Mitochondrial Response in Major Depression: Current Evidence and Further Challenges
inferred← citeshttps://doi.org/10.1155/2022/1041656openalex-snapshot
Involvement of Anti-Inflammatory and Stress Oxidative Markers in the Antidepressant-like Activity of Aloysia citriodora and Verbascoside on Mice with Bacterial Lipopolysaccharide- (LPS-) Induced Depression
inferred← citeshttps://doi.org/10.1155/2022/2566917openalex-snapshot
Polysaccharides from Polygonatum cyrtonema Hua Reduce Depression‐Like Behavior in Mice by Inhibiting Oxidative Stress‐Calpain‐1‐NLRP3 Signaling Axis
inferred← citeshttps://doi.org/10.1155/2022/6151847openalex-snapshot
Trametenolic Acid Ameliorates the Progression of Diabetic Nephropathy in db/db Mice via Nrf2/HO-1 and NF-κB-Mediated Pathways
inferred← citeshttps://doi.org/10.1155/2022/7832983openalex-snapshot
Ginkgolide C Alleviates Acute Lung Injury Caused by Paraquat Poisoning via Regulating the Nrf2 and NF‐κB Signaling Pathways
inferred← citeshttps://doi.org/10.1155/2022/8111022openalex-snapshot
Neurobiological Links between Stress, Brain Injury, and Disease
inferred← citeshttps://doi.org/10.1159/000538348openalex-snapshot
S-Nitrosoglutathione Attenuates Oxidative Stress and Improves Retention Memory Dysfunctions in Intra-Cerebroventricular-Streptozotocin Rat Model of Sporadic Alzheimer’s Disease via Activation of BDNF and Nuclear Factor Erythroid 2-Related Factor-2 Antioxidant Signaling Pathway
inferred← citeshttps://doi.org/10.1161/strokeaha.125.051788openalex-snapshot
Single-Cell Sequencing of Human Neural Organoids in a Model of Intracerebral Hemorrhage Reveals Temporally Dynamic Responses to Blood
inferred← citeshttps://doi.org/10.1186/s12951-023-02008-9openalex-snapshot
Self-immolative nanocapsules precisely regulate depressive neuronal microenvironment for synergistic antidepression therapy
inferred← citeshttps://doi.org/10.1186/s12974-018-1294-2openalex-snapshot
Intracellular inflammatory and antioxidant pathways in postmortem frontal cortex of subjects with major depression: effect of antidepressants
inferred← citeshttps://doi.org/10.1186/s12974-022-02400-6openalex-snapshot
Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway
inferred← citeshttps://doi.org/10.1186/s12974-023-02875-xopenalex-snapshot
Nrf2 regulates iron-dependent hippocampal synapses and functional connectivity damage in depression
inferred← citeshttps://doi.org/10.1186/s13041-019-0463-2openalex-snapshot
Predictable chronic mild stress promotes recovery from LPS-induced depression
inferred← citeshttps://doi.org/10.1186/s13046-019-1336-3openalex-snapshot
GKN2 promotes oxidative stress-induced gastric cancer cell apoptosis via the Hsc70 pathway
inferred← citeshttps://doi.org/10.1186/s40035-024-00409-wopenalex-snapshot
Focusing on mitochondria in the brain: from biology to therapeutics
inferred← citeshttps://doi.org/10.1371/journal.pone.0300275openalex-snapshot
Identifying depression’s genetic role as a precursor to sepsis and increased mortality risk: Comprehensive insights from mendelian randomization analysis
inferred← citeshttps://doi.org/10.1371/journal.pone.0305358openalex-snapshot
6-shogaol against 3-Nitropropionic acid-induced Huntington’s disease in rodents: Based on molecular docking/targeting pro-inflammatory cytokines/NF-κB-BDNF-Nrf2 pathway
inferred← citeshttps://doi.org/10.1523/eneuro.0179-18.2019openalex-snapshot
Effects of Single Cage Housing on Stress, Cognitive, and Seizure Parameters in the Rat and Mouse Pilocarpine Models of Epilepsy
inferred← citeshttps://doi.org/10.1523/eneuro.0200-23.2023openalex-snapshot
Stress and Epilepsy: Towards Understanding of Neurobiological Mechanisms for Better Management
inferred← citeshttps://doi.org/10.1523/eneuro.0426-23.2024openalex-snapshot
Molecular and Functional Alterations in the Cerebral Microvasculature in an Optimized Mouse Model of Sepsis-Associated Cognitive Dysfunction
inferred← citeshttps://doi.org/10.1590/fst.010523openalex-snapshot
Extraction of echinacoside from Cistanche tubulosa (Schenk) R. Wight and investigation of its protective effect on liver injury in sepsis rats
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1567969/v1openalex-snapshot
Spectrum-effect relationship between GC-MS fingerprints and antidepressant-like effect of Schisandra chinensis (Turcz.) Baill. essential oil
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2569163/v1openalex-snapshot
Bdnf-Nrf-2 crosstalk and emotional behavior are disrupted in a sex-dependent fashion in adolescent mice exposed to maternal stress or maternal obesity
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2975443/v1openalex-snapshot
Neurotrophin-loaded PDADMAC/HEPARIN multilayers as an unexpected system to damage neuroblastoma cancer cells
inferred← citeshttps://doi.org/10.21203/rs.3.rs-6192393/v1openalex-snapshot
Overexpression of Hspa1b in the Mouse Hippocampus Is Associated with Major Depressive Disorder
inferred← citeshttps://doi.org/10.2139/ssrn.5228120openalex-snapshot
Systemic Sclerosis and its Cerebral, Neurological, and Psychiatric Impacts: A Narrative Review
inferred← citeshttps://doi.org/10.2147/dddt.s278153openalex-snapshot
Evaluation of the Effect of Hypericum triquetrifolium Turra on Memory Impairment Induced by Chronic Psychosocial Stress in Rats: Role of BDNF
inferred← citeshttps://doi.org/10.2147/jep.s589790openalex-snapshot
Mangiferin Mitigates Ketamine-Induced Dopaminergic and Glial Dysregulation and Modulates Nrf2 Expression in a Rat Schizophrenia-Like Model
inferred← citeshttps://doi.org/10.2147/jpr.s600859openalex-snapshot
Psychological Subtypes and Intervention Strategies in Burning Mouth Syndrome: A Narrative Review
inferred← citeshttps://doi.org/10.2174/0113894501394957250818110931openalex-snapshot
Betaine, a Potential Therapeutic Alternative for the Treatment of Depression
inferred← citeshttps://doi.org/10.2174/1874467212666191203101606openalex-snapshot
Therapeutic Targets for the Treatment of Comorbidities Associated with Epilepsy
inferred← citeshttps://doi.org/10.22141/2224-0721.22.1.2026.1680openalex-snapshot
Depression, type 2 diabetes mellitus, and omega-3 polyunsaturated fatty acids
inferred← citeshttps://doi.org/10.31661/gmj.v10i.2074openalex-snapshot
Nrf2 Dysregulation in Major Depressive and Bipolar Disorders
inferred← citeshttps://doi.org/10.33377/jkh.v8i2.189openalex-snapshot
Pengaruh Ekstrak Biji Kopi Robusta Terhadap Histopatologi Duodenum Yang Diinduksi Monosodium Glutamat Pada Tikus Sprague-dawley
inferred← citeshttps://doi.org/10.3389/fimmu.2019.01511openalex-snapshot
Melatonin Attenuates LPS-Induced Acute Depressive-Like Behaviors and Microglial NLRP3 Inflammasome Activation Through the SIRT1/Nrf2 Pathway
inferred← citeshttps://doi.org/10.3389/fnbeh.2024.1477984openalex-snapshot
Oxidative stress in the brain is regulated by social status in a highly social cichlid fish
inferred← citeshttps://doi.org/10.3389/fncel.2019.00275openalex-snapshot
Electroacupuncture Pretreatment Ameliorates PTSD-Like Behaviors in Rats by Enhancing Hippocampal Neurogenesis via the Keap1/Nrf2 Antioxidant Signaling Pathway
inferred← citeshttps://doi.org/10.3389/fncel.2019.00438openalex-snapshot
Caffeine Consumption During Pregnancy Accelerates the Development of Cognitive Deficits in Offspring in a Model of Tauopathy
inferred← citeshttps://doi.org/10.3389/fneur.2026.1860227openalex-snapshot
Exercise modulation of BDNF/TrkB signaling in Parkinson’s disease: an evidence-calibrated review of neuroprotective mechanisms, biomarker limitations, and translational gaps
inferred← citeshttps://doi.org/10.3389/fnins.2016.00495openalex-snapshot
Low β2 Main Peak Frequency in the Electroencephalogram Signs Vulnerability to Depression
inferred← citeshttps://doi.org/10.3389/fnins.2019.00048openalex-snapshot
Noxious Iron–Calcium Connections in Neurodegeneration
inferred← citeshttps://doi.org/10.3389/fnins.2023.1198291openalex-snapshot
Editorial: Gut microbiota as a therapeutic target in neuropsychiatric disorders: current status and future directions
inferred← citeshttps://doi.org/10.3389/fnins.2025.1559597openalex-snapshot
Ferroptosis-associated signaling pathways and therapeutic approaches in depression
inferred← citeshttps://doi.org/10.3389/fnins.2025.1693696openalex-snapshot
Social isolation: an integrated molecular web that disrupts cellular homeostasis
inferred← citeshttps://doi.org/10.3389/fnmol.2018.00257openalex-snapshot
Integrated Analysis Reveals Altered Lipid and Glucose Metabolism and Identifies NOTCH2 as a Biomarker for Parkinson's Disease Related Depression
inferred← citeshttps://doi.org/10.3389/fphar.2018.01182openalex-snapshot
Essential Role of Keap1-Nrf2 Signaling in Mood Disorders: Overview and Future Perspective
inferred← citeshttps://doi.org/10.3389/fphar.2019.00452openalex-snapshot
Quinolinic Acid and Nuclear Factor Erythroid 2-Related Factor 2 in Depression: Role in Neuroprogression
inferred← citeshttps://doi.org/10.3389/fphar.2021.643456openalex-snapshot
Xiaoyao Pills Ameliorate Depression-like Behaviors and Oxidative Stress Induced by Olfactory Bulbectomy in Rats via the Activation of the PIK3CA-AKT1-NFE2L2/BDNF Signaling Pathway
inferred← citeshttps://doi.org/10.3389/fphar.2022.988648openalex-snapshot
The treatment of depression — searching for new ideas
inferred← citeshttps://doi.org/10.3389/fphar.2024.1348019openalex-snapshot
A review of the pharmacological action and mechanism of natural plant polysaccharides in depression
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