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Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Molecular mechanisms underlying activity-dependent regulation of BDNF expression
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Regenerated Synapses Between Postnatal Hair Cells and Auditory Neurons
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Genes and the hypothalamic control of metabolism in humans
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Quantitative promoter DNA methylation analysis of four candidate genes in anorexia nervosa: A pilot study
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inferredcites →https://doi.org/10.1016/j.pnpbp.2008.12.009openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.psyneuen.2006.11.003openalex-snapshot
Family trios analysis of common polymorphisms in the obestatin/ghrelin, BDNF and AGRP genes in patients with Anorexia nervosa: Association with subtype, body-mass index, severity and age of onset
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inferredcites →https://doi.org/10.1016/s0006-3223(02)01746-8openalex-snapshot
Decreased levels of serum brain-derived neurotrophic factor in female patients with eating disorders
inferredcites →https://doi.org/10.1016/s0092-8674(00)81865-6openalex-snapshot
Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice
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Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis
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inferredcites →https://doi.org/10.1016/s0896-6273(00)81011-9openalex-snapshot
Identification of a Signaling Pathway Involved in Calcium Regulation of BDNF Expression
inferredcites →https://doi.org/10.1016/s0896-6273(01)00561-xopenalex-snapshot
A Calcium-Responsive Transcription Factor, CaRF, that Regulates Neuronal Activity-Dependent Expression of BDNF
inferredcites →https://doi.org/10.1017/s0033291704003368openalex-snapshot
Circulating brain-derived neurotrophic factor is decreased in women with anorexia and bulimia nervosa but not in women with binge-eating disorder: relationships to co-morbid depression, psychopathology and hormonal variables
inferredcites →https://doi.org/10.1017/s0033291708004108openalex-snapshot
Brain-derived neurotrophic factor (BDNF) and set-shifting in currently ill and recovered anorexia nervosa (AN) patients
inferredcites →https://doi.org/10.1017/s1121189x00000956openalex-snapshot
Eating disorders and obesity: two sides of the same coin?
inferredcites →https://doi.org/10.1023/a:1025635913927openalex-snapshot
Genetic and Environmental Factors in Relative Body Weight and Human Adiposity
inferredcites →https://doi.org/10.1024/1422-4917/a000259openalex-snapshot
Clinical Problems Encountered in the Treatment of Adolescents with Anorexia Nervosa 1Both authors contributed equally.
inferredcites →https://doi.org/10.1038/clpt.2011.253openalex-snapshot
The Genetics of Anorexia Nervosa
inferredcites →https://doi.org/10.1038/mp.2010.107openalex-snapshot
A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa
inferredcites →https://doi.org/10.1038/mp.2013.187openalex-snapshot
A genome-wide association study of anorexia nervosa
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A new highly penetrant form of obesity due to deletions on chromosome 16p11.2
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New genetic loci link adipose and insulin biology to body fat distribution
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Genetic studies of body mass index yield new insights for obesity biology
inferredcites →https://doi.org/10.1038/ncomms2968openalex-snapshot
The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms
inferredcites →https://doi.org/10.1038/ng.2247openalex-snapshot
A genome-wide association meta-analysis identifies new childhood obesity loci
inferredcites →https://doi.org/10.1038/ng.287openalex-snapshot
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
inferredcites →https://doi.org/10.1038/ng.3406openalex-snapshot
An atlas of genetic correlations across human diseases and traits
inferredcites →https://doi.org/10.1038/ng.685openalex-snapshot
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
inferredcites →https://doi.org/10.1038/ng.686openalex-snapshot
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
inferredcites →https://doi.org/10.1038/ng.764openalex-snapshot
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
inferredcites →https://doi.org/10.1038/ng1001-166openalex-snapshot
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
inferredcites →https://doi.org/10.1038/sj.ejhg.5201351openalex-snapshot
Association of BDNF with restricting anorexia nervosa and minimum body mass index: a family-based association study of eight European populations
inferredcites →https://doi.org/10.1038/sj.mp.4001281openalex-snapshot
Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type
inferredcites →https://doi.org/10.1038/sj.mp.4001909openalex-snapshot
The role of leptin in anorexia nervosa: clinical implications
inferredcites →https://doi.org/10.1083/jcb.200210164openalex-snapshot
The FGF receptor uses the endocannabinoid signaling system to couple to an axonal growth response
inferredcites →https://doi.org/10.1093/hmg/ddh137openalex-snapshot
Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations
inferredcites →https://doi.org/10.1093/hmg/dds396openalex-snapshot
Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals
inferredcites →https://doi.org/10.1097/00041444-200506000-00003openalex-snapshot
Polymorphisms in the brain-derived neurotrophic factor gene are not associated with either anorexia nervosa or schizophrenia in Dutch patients
inferredcites →https://doi.org/10.1097/01.psy.0000138119.12956.99openalex-snapshot
Opposite Changes in the Serum Brain-Derived Neurotrophic Factor in Anorexia Nervosa and Obesity
inferredcites →https://doi.org/10.1097/ypg.0b013e3280991229openalex-snapshot
BDNF Met66 allele is associated with anorexia nervosa in the Polish population
inferredcites →https://doi.org/10.1101/gad.1666108openalex-snapshot
Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex
inferredcites →https://doi.org/10.1101/gad.1681308openalex-snapshot
Molecular determinants of brown adipocyte formation and function: Figure 1.
inferredcites →https://doi.org/10.1111/j.1601-183x.2007.00301.xopenalex-snapshot
Altered brain‐derived neurotrophic factor blood levels and gene variability are associated with anorexia and bulimia
inferredcites →https://doi.org/10.1111/j.1601-183x.2008.00394.xopenalex-snapshot
Dopaminergic and brain‐derived neurotrophic factor signalling in inbred mice exposed to a restricted feeding schedule
inferredcites →https://doi.org/10.1111/j.1601-183x.2010.00660.xopenalex-snapshot
Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting
inferredcites →https://doi.org/10.1111/jnc.12213openalex-snapshot
Brain‐derived neurotrophic factor, corticotropin‐releasing factor, and hypothalamic neuronal histamine interact to regulate feeding behavior
inferredcites →https://doi.org/10.1124/mol.107.041814openalex-snapshot
Salicylate Alters the Expression of Calcium Response Transcription Factor 1 in the Cochlea: Implications for Brain-Derived Neurotrophic Factor Transcriptional Regulation
inferredcites →https://doi.org/10.1128/mcb.01899-08openalex-snapshot
C/EBPα and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes during Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-Activated Receptor γ Agonists
inferredcites →https://doi.org/10.1128/mcb.22.15.5296-5307.2002openalex-snapshot
Overlapping and Unique Roles for C-Terminal Binding Protein 1 (CtBP1) and CtBP2 during Mouse Development
inferredcites →https://doi.org/10.1136/jmg.2004.018614openalex-snapshot
Large quantitative effect of melanocortin-4 receptor gene mutations on body mass index
inferredcites →https://doi.org/10.1139/jpn.0942openalex-snapshot
Serum brain-derived neurotrophic factor and peripheral indicators of the serotonin system in underweight and weight-recovered adolescent girls and women with anorexia nervosa
inferredcites →https://doi.org/10.1155/2013/384594openalex-snapshot
Variation inHNF1Band Obesity May Influence Prostate Cancer Risk in African American Men: A Pilot Study
inferredcites →https://doi.org/10.1159/000120623openalex-snapshot
Blood Levels of Brain-Derived Neurotrophic Factor Correlate with Several Psychopathological Symptoms in Anorexia Nervosa Patients
inferredcites →https://doi.org/10.1159/000343500openalex-snapshot
Serum Neurotrophin Concentrations in Polish Adolescent Girls with Anorexia Nervosa
inferredcites →https://doi.org/10.1159/000353879openalex-snapshot
Genetics of Food Intake Self-Regulation in Childhood: Literature Review and Research Opportunities
inferredcites →https://doi.org/10.1159/000374032openalex-snapshot
Obesity-Associated MiR-342-3p Promotes Adipogenesis of Mesenchymal Stem Cells by Suppressing CtBP2 and Releasing C/EBPα from CtBP2 Binding
inferredcites →https://doi.org/10.1159/000447701openalex-snapshot
Psychosomatic Medicine in Germany: More Timely than Ever
inferredcites →https://doi.org/10.1176/ajp.154.4.566openalex-snapshot
Prediction of low body weight at long-term follow-up in acute anorexia nervosa by low body weight at referral
inferredcites →https://doi.org/10.1210/en.2005-0419openalex-snapshot
Brain-Derived Neurotrophic Factor Plays a Role as an Anorexigenic Factor in the Dorsal Vagal Complex
inferredcites →https://doi.org/10.1210/en.2009-1057openalex-snapshot
Mechanisms Regulating Repression of Haptoglobin Production by Peroxisome Proliferator-Activated Receptor-γ Ligands in Adipocytes
inferredcites →https://doi.org/10.1210/en.2012-2185openalex-snapshot
A Role for Phosphodiesterase 3B in Acquisition of Brown Fat Characteristics by White Adipose Tissue in Male Mice
inferredcites →https://doi.org/10.1371/journal.pgen.1000916openalex-snapshot
Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups
inferredcites →https://doi.org/10.1371/journal.pgen.1005378openalex-snapshot
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
inferredcites →https://doi.org/10.1371/journal.pone.0010870openalex-snapshot
Genome-Wide Identification of Calcium-Response Factor (CaRF) Binding Sites Predicts a Role in Regulation of Neuronal Signaling Pathways
inferredcites →https://doi.org/10.1371/journal.pone.0051954openalex-snapshot
Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population
inferredcites →https://doi.org/10.1523/jneurosci.0534-12.2012openalex-snapshot
Members of the Myocyte Enhancer Factor 2 Transcription Factor Family Differentially RegulateBdnfTranscription in Response to Neuronal Depolarization
inferredcites →https://doi.org/10.1523/jneurosci.3997-09.2010openalex-snapshot
Reduced Cortical BDNF Expression and Aberrant Memory inCarfKnock-Out Mice
inferredcites →https://doi.org/10.1530/jme-15-0038openalex-snapshot
The effect of myostatin on proliferation and lipid accumulation in 3T3-L1 preadipocytes
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Genetic Risk Factors in Eating Disorders
inferredcites →https://doi.org/10.2217/pgs.15.77openalex-snapshot
Discussing the Putative Role of Obesity-Associated Genes in the Etiopathogenesis of Eating Disorders
inferredcites →https://doi.org/10.3109/15622975.2011.562244openalex-snapshot
A meta-analysis of circulating BDNF concentrations in anorexia nervosa
inferredcites →https://doi.org/10.3109/15622975.2011.605470openalex-snapshot
The Val66Met polymorphism of the BDNF gene in anorexia nervosa: New data and a meta-analysis
inferredcites →https://doi.org/10.3892/or.2014.3668openalex-snapshot
HOXA7 stimulates human hepatocellular carcinoma proliferation through cyclin E1/CDK2
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Appetite Regulatory Hormones in Women With Anorexia Nervosa
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Obesity genetics in mouse and human: back and forth, and back again
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Skin Manifestations of Nutritional Disorders
inferred← citeshttps://doi.org/10.1002/ajmg.b.32709openalex-snapshot
Genomics of body fat percentage may contribute to sex bias in anorexia nervosa
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Influence of TFAP 2B and KCTD 15 genetic variability on personality dimensions in anorexia and bulimia nervosa
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Early childhood adversities and risk of eating disorders in women: A Danish register‐based cohort study
inferred← citeshttps://doi.org/10.1002/eat.23029openalex-snapshot
Why is premorbid BMI consistently elevated in clinical samples, but not in risk factor samples, of individuals with eating disorders?
inferred← citeshttps://doi.org/10.1002/eat.23083openalex-snapshot
Genetic risk, body mass index, and weight control behaviors: Unlocking the triad
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Childhood body mass index and the subsequent risk of anorexia nervosa and bulimia nervosa among women: A large Danish population‐based study
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Genetics of Obesity: What We Have Learned Over Decades of Research
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Shared and distinct genetic architectures of eating disorders and obesity: From monogenic causes to polygenic risk
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Polygene Varianten und Epigenetik bei Adipositas
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Eating Disorders and the Intestinal Microbiota: Mechanisms of Energy Homeostasis and Behavioral Influence
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Genetics of Anorexia Nervosa
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Sex Differences in Adolescent Anorexia and Bulimia Nervosa: Beyond the Signs and Symptoms
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Anti-hypothalamus autoantibodies in anorexia nervosa: a possible new mechanism in neuro-physiological derangement?
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Overarching Key Issues for Feeding, Eating, and Weight Disorders
inferred← citeshttps://doi.org/10.1016/b978-0-323-54852-6.00011-2openalex-snapshot
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Dietary eggs, egg nutrients, polygenic score for body mass index, “Western pattern” diet, and weight change, a prospective analysis in the Women's health initiative
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Genetics of anorexia nervosa: An overview of genome-wide association studies and emerging biological links
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Developmental social vulnerability as the intrinsic origin of psychopathology: A paradigm shift from disease entities to psychiatric derivatives within human diversity
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Ebenen der genetischen Analyse komplexer Phänotypen am Beispiel der Anorexia nervosa und der Varianz des Körpergewichts
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Histone deacetylase 4 (HDAC4): a new player in anorexia nervosa?
inferred← citeshttps://doi.org/10.1038/s41380-024-02601-wopenalex-snapshot
Epigenetic alterations in patients with anorexia nervosa—a systematic review
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Genetic and functional analyses of CTBP2 in anorexia nervosa and body weight regulation
inferred← citeshttps://doi.org/10.1038/s41398-019-0518-2openalex-snapshot
Plasma neurofilament light chain concentration is increased in anorexia nervosa
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PTBP2 – a gene with relevance for both Anorexia nervosa and body weight regulation
inferred← citeshttps://doi.org/10.1038/s41398-023-02428-zopenalex-snapshot
Disrupted longitudinal restoration of brain connectivity during weight normalization in severe anorexia nervosa
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An evolutionary perspective on the genetics of anorexia nervosa
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The transcriptional corepressor CtBP2 serves as a metabolite sensor orchestrating hepatic glucose and lipid homeostasis
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The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits
inferred← citeshttps://doi.org/10.1038/s41598-020-80693-4openalex-snapshot
Alterations in B cell subsets correlate with body composition parameters in female adolescents with anorexia nervosa
inferred← citeshttps://doi.org/10.1038/s41598-022-16495-7openalex-snapshot
Evidence for correlations between BMI-associated SNPs and circRNAs
inferred← citeshttps://doi.org/10.1038/s41598-024-57517-wopenalex-snapshot
Unexpected identification of obesity-associated mutations in LEP and MC4R genes in patients with anorexia nervosa
inferred← citeshttps://doi.org/10.1055/s-0038-1676674openalex-snapshot
Polygene Formen der Adipositas und Störungs-übergreifende Analysen
inferred← citeshttps://doi.org/10.1080/01677063.2017.1353092openalex-snapshot
Molecular bases of anorexia nervosa, bulimia nervosa and binge eating disorder: shedding light on the darkness
inferred← citeshttps://doi.org/10.1093/hmg/ddaa182openalex-snapshot
Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1093/med/9780198713005.003.0102openalex-snapshot
Basic mechanisms and potential for treatment of weight and eating disorders
inferred← citeshttps://doi.org/10.1093/med/9780198713005.003.0104openalex-snapshot
Genetics of feeding and eating disorders
inferred← citeshttps://doi.org/10.1093/nutrit/nuz089openalex-snapshot
The Western diet: a blind spot of eating disorder research?—a narrative review and recommendations for treatment and research
inferred← citeshttps://doi.org/10.1097/ypg.0000000000000224openalex-snapshot
Anorexia nervosa is associated with Neuronatin variants
inferred← citeshttps://doi.org/10.1101/088815openalex-snapshot
Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations
inferred← citeshttps://doi.org/10.1101/264846openalex-snapshot
Cyfip1 haploinsufficiency increases compulsive-like behavior and modulates palatable food intake: Implications for Prader-Willi Syndrome
inferred← citeshttps://doi.org/10.1101/265017openalex-snapshot
Identifying tissues implicated in Anorexia Nervosa using Transcriptomic Imputation
inferred← citeshttps://doi.org/10.1159/000479208openalex-snapshot
A Proposal of the European Association for the Study of Obesity to Improve the ICD-11 Diagnostic Criteria for Obesity Based on the Three Dimensions Etiology, Degree of Adiposity and Health Risk
inferred← citeshttps://doi.org/10.1159/000484525openalex-snapshot
An Evolutionary Genetic Perspective of Eating Disorders
inferred← citeshttps://doi.org/10.1176/appi.ajp.2017.16121402openalex-snapshot
Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa
inferred← citeshttps://doi.org/10.1186/s13148-017-0418-3openalex-snapshot
Maternal eating disorders affect offspring cord blood DNA methylation: a prospective study
inferred← citeshttps://doi.org/10.1186/s13293-026-00943-4openalex-snapshot
Sex-stratified insights into the genetics of brain volumes in late adulthood
inferred← citeshttps://doi.org/10.1186/s40337-024-00998-xopenalex-snapshot
Temperament impact on eating disorder symptoms and habit formation: a novel model to inform treatment
inferred← citeshttps://doi.org/10.1242/dmm.027433openalex-snapshot
The tyrosine kinase receptor Tyro3 enhances lifespan and neuropeptide Y (Npy) neuron survival in the mouseanorexia(anx) mutation
inferred← citeshttps://doi.org/10.1371/journal.pone.0173560openalex-snapshot
Fat mass and obesity-associated gene (FTO) is associated to eating disorders susceptibility and moderates the expression of psychopathological traits
inferred← citeshttps://doi.org/10.1515/medgen-2020-2005openalex-snapshot
Genetic and epigenetic findings in anorexia nervosa
inferred← citeshttps://doi.org/10.15167/2421-4248/jpmh2022.63.2s3.2772openalex-snapshot
Gene variants in Eating Disorders. Focus on Anorexia Nervosa Bulimia Nervosa and Binge-eating Disorder
inferred← citeshttps://doi.org/10.1530/ec-21-0111openalex-snapshot
Appetite- and weight-inducing and -inhibiting neuroendocrine factors in Prader–Willi syndrome, Bardet–Biedl syndrome and craniopharyngioma versus anorexia nervosa
inferred← citeshttps://doi.org/10.1534/g3.119.400470openalex-snapshot
Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex
inferred← citeshttps://doi.org/10.1590/1516-4446-2020-1099openalex-snapshot
Risk factors for eating disorders: an umbrella review of published meta-analyses
inferred← citeshttps://doi.org/10.25118/2763-9037.2022.v12.460openalex-snapshot
Fatores de risco de transtornos alimentares: revisão guarda-chuva de metanálises publicadas
inferred← citeshttps://doi.org/10.3389/fgene.2023.1128133openalex-snapshot
Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa
inferred← citeshttps://doi.org/10.3389/fnins.2019.00059openalex-snapshot
The anx/anx Mouse – A Valuable Resource in Anorexia Nervosa Research
inferred← citeshttps://doi.org/10.3389/fpsyt.2022.960905openalex-snapshot
Expression of CXCR4 on CD4+ T cells predicts body composition parameters in female adolescents with anorexia nervosa
inferred← citeshttps://doi.org/10.3390/jcm9041187openalex-snapshot
Polygenic Score for Body Mass Index Is Associated with Disordered Eating in a General Population Cohort
inferred← citeshttps://doi.org/10.3390/nu13124321openalex-snapshot
Obesity and Eating Disorders in Children and Adolescents: The Bidirectional Link
inferred← citeshttps://doi.org/10.5114/aoms/113174openalex-snapshot
Association of PRDM16 rs12409277 and CtBP2 rs1561589 gene polymorphisms with lipid profile of adolescents
inferred← citeshttps://doi.org/10.64898/2026.01.09.698629openalex-snapshot
Sex-stratified insights into the genetics of brain volumes in late adulthood
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