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Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Iron and Oxidative Stress in Bacteria
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The F Plasmid CcdB Protein Induces Efficient ATP-dependent DNA Cleavage by Gyrase
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The Complex of DNA Gyrase and Quinolone Drugs with DNA Forms a Barrier to Transcription by RNA Polymerase
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DNA Gyrase and Topoisomerase IV on the Bacterial Chromosome: Quinolone-induced DNA Cleavage
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The interaction of the F plasmid killer protein, CcdB, with DNA gyrase: induction of DNA cleavage and blocking of transcription 1 1J. Karn
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Localization of Fe2+ at an RTGR sequence within a DNA duplex explains preferential cleavage by Fe2+ and H2O211Edited by M. F. Summers
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Evolution of cellular ATP concentration after UV-mediated induction of SOS system in Escherichiacoli
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Marker-specific effects in genetic recombination
inferredcites →https://doi.org/10.1016/0022-2836(83)90074-8openalex-snapshot
Proteins required for ultraviolet light and chemical mutagenesis
inferredcites →https://doi.org/10.1016/0022-2836(92)90629-xopenalex-snapshot
Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes
inferredcites →https://doi.org/10.1016/0022-2836(92)91024-jopenalex-snapshot
Control of segregation of chromosomal DNA by sex factor F in Escherichia coli
inferredcites →https://doi.org/10.1016/0092-8674(82)90085-xopenalex-snapshot
The SOS regulatory system of Escherichia coli
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Protection of mammalian cells by o-phenanthroline from lethal and DNA-damaging effects produced by active oxygen species
inferredcites →https://doi.org/10.1016/0300-9084(91)90108-dopenalex-snapshot
Mechanism of specific LexA cleavage: Autodigestion and the role of RecA coprotease
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FACS-optimized mutants of the green fluorescent protein (GFP)
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DNA mismatch repair-induced double-strand breaks
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Biogenesis of iron–sulfur proteins in eukaryotes: a novel task of mitochondria that is inherited from bacteria
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Functional differences between manganese and iron superoxide dismutases in Escherichia coli K-12.
inferredcites →https://doi.org/10.1016/s0021-9258(18)41538-4openalex-snapshot
The inactivation of Fe-S cluster containing hydro-lyases by superoxide.
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Iron Ion-dependent Modification of Bases in DNA by the Superoxide Radical-generating System Hypoxanthine/Xanthine Oxidase
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Modulation of DNA supercoiling activity of Escherichia coli DNA gyrase by F plasmid proteins. Antagonistic actions of LetA (CcdA) and LetD (CcdB) proteins.
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THE INHIBITION OF MITOCHONDRIAL RESPIRATION BY 1,10-PHENANTHROLINE AND 2,2'-BIPYRIDINE AND THE POSSIBLE RELATIONSHIP TO OXIDATIVE PHOSPHORYLATION
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Overlapping and separate controls on the phosphate regulon in Escherichia coli K12
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Zn, Cu and Co in cyanobacteria: selective control of metal availability
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Bacterial iron homeostasis
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Bacterial death by DNA gyrase poisoning
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Reactive oxygen species and programmed cell death
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Mutagenic spectrum resulting from DNA damage by oxygen radicals
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Role of reactive oxygen species (ROS) in apoptosis induction
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The importance of repairing stalled replication forks
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Gene Ontology: tool for the unification of biology
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Construction of Escherichia coli K‐12 in‐frame, single‐gene knockout mutants: the Keio collection
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Engineered riboregulators enable post-transcriptional control of gene expression
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The evolution of genetic regulatory systems in bacteria
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Where will new antibiotics come from?
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Managing DNA polymerases: Coordinating DNA replication, DNA repair, and DNA recombination
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The cysteine desulfurase, IscS, has a major role in in vivo Fe-S cluster formation in Escherichia coli
inferredcites →https://doi.org/10.1073/pnas.251550898openalex-snapshot
IscR, an Fe-S cluster-containing transcription factor, represses expression of Escherichia coli genes encoding Fe-S cluster assembly proteins
inferredcites →https://doi.org/10.1073/pnas.69.11.3479openalex-snapshot
Fine-Structure Deletion Map of the Escherichia coli L-Arabinose Operon
inferredcites →https://doi.org/10.1073/pnas.73.11.3872openalex-snapshot
DNA gyrase: an enzyme that introduces superhelical turns into DNA.
inferredcites →https://doi.org/10.1073/pnas.74.12.5275openalex-snapshot
Protein X is the product of the recA gene of Escherichia coli.
inferredcites →https://doi.org/10.1073/pnas.75.12.5960openalex-snapshot
DNA gyrase: subunit structure and ATPase activity of the purified enzyme.
inferredcites →https://doi.org/10.1073/pnas.77.5.2819openalex-snapshot
DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli.
inferredcites →https://doi.org/10.1073/pnas.93.24.13635openalex-snapshot
Superoxide accelerates DNA damage by elevating free-iron levels
inferredcites →https://doi.org/10.1073/pnas.95.17.9738openalex-snapshot
DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone
inferredcites →https://doi.org/10.1074/jbc.272.30.18515openalex-snapshot
Superoxide Anion Radical (O·2), Superoxide Dismutases, and Related Matters
inferredcites →https://doi.org/10.1074/jbc.272.8.5082openalex-snapshot
Regulation of the soxRS Oxidative Stress Regulon
inferredcites →https://doi.org/10.1074/jbc.273.21.13264openalex-snapshot
Assembly of Iron-Sulfur Clusters
inferredcites →https://doi.org/10.1074/jbc.273.35.22615openalex-snapshot
The DNA Gyrase-Quinolone Complex
inferredcites →https://doi.org/10.1074/jbc.273.46.30232openalex-snapshot
Reversible Induction of ATP Synthesis by DNA Damage and Repair in Escherichia coli
inferredcites →https://doi.org/10.1074/jbc.274.2.962openalex-snapshot
Sequence-specific DNA Cleavage by Fe2+-mediated Fenton Reactions Has Possible Biological Implications
inferredcites →https://doi.org/10.1074/jbc.274.49.34832openalex-snapshot
Role of Iron and Superoxide for Generation of Hydroxyl Radical, Oxidative DNA Lesions, and Mutagenesis in Escherichia coli
inferredcites →https://doi.org/10.1074/jbc.m204958200openalex-snapshot
Mechanism of Superoxide and Hydrogen Peroxide Formation by Fumarate Reductase, Succinate Dehydrogenase, and Aspartate Oxidase
inferredcites →https://doi.org/10.1074/jbc.m209264200openalex-snapshot
Development of Novel Fluorescence Probes That Can Reliably Detect Reactive Oxygen Species and Distinguish Specific Species
inferredcites →https://doi.org/10.1074/jbc.m303381200openalex-snapshot
Global Iron-dependent Gene Regulation in Escherichia coli
inferredcites →https://doi.org/10.1074/jbc.m406487200openalex-snapshot
Repair of Oxidized Iron-Sulfur Clusters in Escherichia coli
inferredcites →https://doi.org/10.1080/152165499307161openalex-snapshot
Superoxide and Iron: Partners in Crime
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Oxygen Stress: A Regulator of Apoptosis in Yeast
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Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.
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GO::TermFinder—open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes
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Exploration, normalization, and summaries of high density oligonucleotide array probe level data
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The redox‐regulated SoxR protein acts from a single DNA site as a repressor and an allosteric activator
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Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elements
inferredcites →https://doi.org/10.1093/nar/8.17.3865openalex-snapshot
DNA gyrase subunit stoichiometry and the covalent attachment of subunit A to DNA during DNA cleavage
inferredcites →https://doi.org/10.1093/nar/gkh021openalex-snapshot
The Gene Ontology Annotation (GOA) Database: sharing knowledge in Uniprot with Gene Ontology
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RegulonDB (version 5.0): Escherichia coli K-12 transcriptional regulatory network, operon organization, and growth conditions
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Fur-mediated transcriptional and post-transcriptional regulation of FeSOD expression in Escherichia coli
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Isolation of Differentiated Squamous and Undifferentiated Spindle Carcinoma Cell Lines with Differing Metastatic Potential from a 4‐Nitroquinoline N‐Oxide‐induced Tongue Carcinoma in a F344 Rat
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A suf operon requirement for Fe–S cluster assembly during iron starvation in Escherichia coli
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Iron‐sulphur clusters and the problem with oxygen
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IscR‐dependent gene expression links iron‐sulphur cluster assembly to the control of O 2 ‐regulated genes in Escherichia coli
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Combining probability from independent tests: the weighted Z ‐method is superior to Fisher's approach
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THE U.V. SENSITIVITY OF BACTERIA: ITS RELATION TO THE DNA REPLICATION CYCLE
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DISC ELECTROPHORESIS OF IRRADIATED TRYPSIN*
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Mitochondria and Apoptosis
inferredcites →https://doi.org/10.1126/science.2834821openalex-snapshot
Toxic DNA Damage by Hydrogen Peroxide Through the Fenton Reaction in Vivo and in Vitro
inferredcites →https://doi.org/10.1126/science.3287616openalex-snapshot
DNA Damage and Oxygen Radical Toxicity
inferredcites →https://doi.org/10.1126/science.6243420openalex-snapshot
DNA Gyrase and the Supercoiling of DNA
inferredcites →https://doi.org/10.1128/aac.42.5.1022openalex-snapshot
Modulation of Gyrase-Mediated DNA Cleavage and Cell Killing by ATP
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Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli
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Escherichia coli Mutants Thermosensitive for Deoxyribonucleic Acid Gyrase Subunit A: Effects on Deoxyribonucleic Acid Replication, Transcription, and Bacteriophage Growth
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Effects of the ccd function of the F plasmid on bacterial growth
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Effects of metal ion chelators on DNA strand breaks and inactivation produced by hydrogen peroxide in Escherichia coli: detection of iron-independent lesions
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Lethal oxidative damage and mutagenesis are generated by iron in delta fur mutants of Escherichia coli: protective role of superoxide dismutase
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Opening the Iron Box: Transcriptional Metalloregulation by the Fur Protein
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Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli
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DNA gyrase, topoisomerase IV, and the 4-quinolones
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Oxidative stress responses in Escherichia coli and Salmonella typhimurium
inferredcites →https://doi.org/10.1146/annurev.bi.50.070181.004311openalex-snapshot
DNA Topoisomerases
inferredcites →https://doi.org/10.1146/annurev.bi.65.070196.003223openalex-snapshot
DNA TOPOISOMERASES
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DNA Topoisomerases: Structure, Function, and Mechanism
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STRUCTURE, FUNCTION, AND FORMATION OF BIOLOGICAL IRON-SULFUR CLUSTERS
inferredcites →https://doi.org/10.1146/annurev.genet.37.110801.142616openalex-snapshot
RecA-Dependent Recovery of Arrested DNA Replication Forks
inferredcites →https://doi.org/10.1146/annurev.micro.57.030502.090938openalex-snapshot
Pathways of Oxidative Damage
inferredcites →https://doi.org/10.1152/ajpcell.00139.2004openalex-snapshot
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
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Large-Scale Mapping and Validation of Escherichia coli Transcriptional Regulation from a Compendium of Expression Profiles
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Structural Biology of Bacterial Iron Uptake Systems
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DNA Gyrase: Structure and Function
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Superoxide Production by Respiring Membranes ofEscherichia Coli
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Commentary: The Role of Iron-Sulfur Clusters inin vivoHydroxyl Radical Production
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Mechanism of Action and Clinical Attributes of Auryxia® (Ferric Citrate)
inferred← citeshttps://doi.org/10.1007/s40726-024-00320-yopenalex-snapshot
New Insights into Removing Antibiotic Resistance Genes: Environmental Factors, Technical Means, and Molecular Mechanisms
inferred← citeshttps://doi.org/10.1016/b978-0-12-382030-3.00007-6openalex-snapshot
Drug Resistance and Drug Synergism
inferred← citeshttps://doi.org/10.1016/b978-0-12-800051-9.00021-3openalex-snapshot
Chronic Infection with Pseudomonas aeruginosa in an Animal Model of Oxidative Stress
inferred← citeshttps://doi.org/10.1016/b978-008045382-8.00161-1openalex-snapshot
Enzymology of Bacterial Resistance
inferred← citeshttps://doi.org/10.1016/bs.enz.2019.08.003openalex-snapshot
Iron–sulfur clusters in nucleic acid metabolism: Varying roles of ancient cofactors
inferred← citeshttps://doi.org/10.1016/j.addr.2016.04.006openalex-snapshot
Synthetic biology platform technologies for antimicrobial applications
inferred← citeshttps://doi.org/10.1016/j.aquatox.2025.107284openalex-snapshot
Antibacterials exert toxic effects on aquatic organisms by inhibiting respiration, inducing oxidative stress, mitochondrial dysfunction and autophagy
inferred← citeshttps://doi.org/10.1016/j.bbagen.2015.02.012openalex-snapshot
Action mechanism of 6, 6′-dihydroxythiobinupharidine from Nuphar japonicum, which showed anti-MRSA and anti-VRE activities
inferred← citeshttps://doi.org/10.1016/j.bbrc.2020.07.010openalex-snapshot
Quantitative secretome analysis of polymyxin B resistance in Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.bcp.2017.01.015openalex-snapshot
Synthetic biology era: Improving antibiotic’s world
inferred← citeshttps://doi.org/10.1016/j.bioflm.2024.100203openalex-snapshot
Oxidative stress responses in biofilms
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2015.12.027openalex-snapshot
The interplay between biological and physical scenarios of bacterial death induced by non-thermal plasma
inferred← citeshttps://doi.org/10.1016/j.biortech.2026.135692openalex-snapshot
Ergothioneine improves methane recovery and reduces indicators of oxidative stress in ammonia-stressed food waste anaerobic digestion
inferred← citeshttps://doi.org/10.1016/j.bmcl.2011.08.052openalex-snapshot
Chemical scaffolds with structural similarities to siderophores of nonribosomal peptide–polyketide origin as novel antimicrobials against Mycobacterium tuberculosis and Yersinia pestis
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.07.040openalex-snapshot
Synthesis, antimycobacterial and antibacterial activity of ciprofloxacin derivatives containing a N-substituted benzyl moiety
inferred← citeshttps://doi.org/10.1016/j.carbpol.2014.03.069openalex-snapshot
Increasing viscosity and yields of bacterial exopolysaccharides by repeatedly exposing strains to ampicillin
inferred← citeshttps://doi.org/10.1016/j.cclet.2025.110907openalex-snapshot
Recent progress on drug delivery systems of regulating intratumoral bacteria for tumor therapy
inferred← citeshttps://doi.org/10.1016/j.cell.2007.06.049openalex-snapshot
A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics
inferred← citeshttps://doi.org/10.1016/j.cell.2008.09.038openalex-snapshot
Mistranslation of Membrane Proteins and Two-Component System Activation Trigger Antibiotic-Mediated Cell Death
inferred← citeshttps://doi.org/10.1016/j.cell.2009.10.025openalex-snapshot
Nonoptimal Microbial Response to Antibiotics Underlies Suppressive Drug Interactions
inferred← citeshttps://doi.org/10.1016/j.celrep.2012.12.021openalex-snapshot
Fungicidal Drugs Induce a Common Oxidative-Damage Cellular Death Pathway
inferred← citeshttps://doi.org/10.1016/j.celrep.2013.01.026openalex-snapshot
YihE Kinase Is a Central Regulator of Programmed Cell Death in Bacteria
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.09.059openalex-snapshot
Bactericidal Antibiotics Induce Toxic Metabolic Perturbations that Lead to Cellular Damage
inferred← citeshttps://doi.org/10.1016/j.celrep.2015.12.060openalex-snapshot
Conditional Epistatic Interaction Maps Reveal Global Functional Rewiring of Genome Integrity Pathways in Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117611openalex-snapshot
Pyruvate-formate lyase-derived formate regulates the response of Salmonella Typhimurium to meropenem and ciprofloxacin
inferred← citeshttps://doi.org/10.1016/j.chembiol.2008.10.007openalex-snapshot
Known Bioactive Small Molecules Probe the Function of a Widely Conserved but Enigmatic Bacterial ATPase, YjeE
inferred← citeshttps://doi.org/10.1016/j.chembiol.2010.06.008openalex-snapshot
Chemical Probes of Escherichia coli Uncovered through Chemical-Chemical Interaction Profiling with Compounds of Known Biological Activity
inferred← citeshttps://doi.org/10.1016/j.chembiol.2016.12.015openalex-snapshot
Carbon Sources Tune Antibiotic Susceptibility in Pseudomonas aeruginosa via Tricarboxylic Acid Cycle Control
inferred← citeshttps://doi.org/10.1016/j.chembiol.2021.02.022openalex-snapshot
Bioreporters for direct mode of action-informed screening of antibiotic producer strains
inferred← citeshttps://doi.org/10.1016/j.chom.2013.05.009openalex-snapshot
Microbial Persistence and the Road to Drug Resistance
inferred← citeshttps://doi.org/10.1016/j.cmet.2019.06.009openalex-snapshot
Bacterial Metabolism and Antibiotic Efficacy
inferred← citeshttps://doi.org/10.1016/j.cmet.2019.08.020openalex-snapshot
Microbial Metabolism Modulates Antibiotic Susceptibility within the Murine Gut Microbiome
inferred← citeshttps://doi.org/10.1016/j.coph.2008.04.009openalex-snapshot
Recent advances in bacterial topoisomerase inhibitors
inferred← citeshttps://doi.org/10.1016/j.csbj.2024.05.020openalex-snapshot
A novel cathelicidin TS-CATH derived from Thamnophis sirtalis combats drug-resistant gram-negative bacteria in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2022.114218openalex-snapshot
Aged microplastics enhance their interaction with ciprofloxacin and joint toxicity on Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.ejmech.2010.08.050openalex-snapshot
Synthesis and in vitro antibacterial activity of fluoroquinolone derivatives containing 3-(N′-alkoxycarbamimidoyl)-4-(alkoxyimino) pyrrolidines
inferred← citeshttps://doi.org/10.1016/j.ejmech.2011.10.048openalex-snapshot
Synthesis and antibacterial activity of naphthyridone derivatives containing mono/difluoro-methyloxime pyrrolidine scaffolds
inferred← citeshttps://doi.org/10.1016/j.ejmech.2012.07.010openalex-snapshot
Synthesis and in vitro antibacterial activity of gemifloxacin derivatives containing a substituted benzyloxime moiety
inferred← citeshttps://doi.org/10.1016/j.ejmech.2013.01.057openalex-snapshot
Antibacterial action of quinolones: From target to network
inferred← citeshttps://doi.org/10.1016/j.ejmech.2016.07.058openalex-snapshot
FtsZ inhibition and redox modulation with one chemical scaffold: Potential use of dihydroquinolines against mycobacteria
inferred← citeshttps://doi.org/10.1016/j.envpol.2026.128683openalex-snapshot
The role of intracellular ROS in the development of antimicrobial resistance:A convergent mediator linking mutations and horizontal gene transfer
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2020.10.322openalex-snapshot
The alarmone (p)ppGpp confers tolerance to oxidative stress during the stationary phase by maintenance of redox and iron homeostasis in Staphylococcus aureus
inferred← citeshttps://doi.org/10.1016/j.ijfoodmicro.2022.109929openalex-snapshot
Ferrous sulfate efficiently kills Vibrio parahaemolyticus and protects salmon sashimi from its contamination
inferred← citeshttps://doi.org/10.1016/j.isci.2024.109825openalex-snapshot
Phagosomal granulocytic ROS in septic patients induce the bacterial SOS response
inferred← citeshttps://doi.org/10.1016/j.jece.2026.121602openalex-snapshot
Antimicrobial activities and low toxicity potential of polyhalogenated phenols against Staphylococcus aureus
inferred← citeshttps://doi.org/10.1016/j.jenvman.2021.113315openalex-snapshot
Mobility of antibiotic resistance and its co-occurrence with metal resistance in pathogens under oxidative stress
inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.135783openalex-snapshot
Metabolic variation and oxidative stress responses of clams (Ruditapes philippinarum) perturbed by ofloxacin exposure
inferred← citeshttps://doi.org/10.1016/j.jiec.2015.04.005openalex-snapshot
Biologically synthesized silver nanoparticles enhances antibiotic activity against Gram-negative bacteria
inferred← citeshttps://doi.org/10.1016/j.jinorgbio.2009.07.009openalex-snapshot
Superoxide protects Escherichia coli from bleomycin mediated lethality
inferred← citeshttps://doi.org/10.1016/j.jprot.2016.04.032openalex-snapshot
How different is the proteome of the extended spectrum β-lactamase producing Escherichia coli strains from seagulls of the Berlengas natural reserve of Portugal?
inferred← citeshttps://doi.org/10.1016/j.mib.2009.06.018openalex-snapshot
Role of reactive oxygen species in antibiotic action and resistance
inferred← citeshttps://doi.org/10.1016/j.mib.2011.09.002openalex-snapshot
Heterogeneous bacterial persisters and engineering approaches to eliminate them
inferred← citeshttps://doi.org/10.1016/j.mib.2015.01.004openalex-snapshot
Diagnosing oxidative stress in bacteria: not as easy as you might think
inferred← citeshttps://doi.org/10.1016/j.micpath.2019.03.011openalex-snapshot
Lophirones B and C induce oxidative cellular death pathway in Acinetobacter baumannii by inhibiting DNA gyrase
inferred← citeshttps://doi.org/10.1016/j.micres.2012.10.003openalex-snapshot
Antibacterial activity of CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine) generating reactive oxygen species
inferred← citeshttps://doi.org/10.1016/j.micres.2013.06.013openalex-snapshot
Medicinal plant extracts variously modulate susceptibility of Escherichia coli to different antibiotics
inferred← citeshttps://doi.org/10.1016/j.micres.2024.127711openalex-snapshot
Ferrous gluconate triggers ferroptosis in Escherichia coli: Implications of lipid peroxidation and DNA damage
inferred← citeshttps://doi.org/10.1016/j.micres.2026.128574openalex-snapshot
Type VI secretion system: Central regulator of antimicrobial resistance dynamics via indirect mechanisms
inferred← citeshttps://doi.org/10.1016/j.molcel.2009.11.024openalex-snapshot
Hydroxyurea Induces Hydroxyl Radical-Mediated Cell Death in Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.molcel.2010.01.003openalex-snapshot
Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis
inferred← citeshttps://doi.org/10.1016/j.molcel.2011.04.016openalex-snapshot
Resolution of Gene Regulatory Conflicts Caused by Combinations of Antibiotics
inferred← citeshttps://doi.org/10.1016/j.molcel.2012.04.027openalex-snapshot
Antibiotic-Induced Bacterial Cell Death Exhibits Physiological and Biochemical Hallmarks of Apoptosis
inferred← citeshttps://doi.org/10.1016/j.molcel.2012.05.032openalex-snapshot
When Death Was Young: An Ancestral Apoptotic Network in Bacteria
inferred← citeshttps://doi.org/10.1016/j.molcel.2019.02.037openalex-snapshot
Gamblers: An Antibiotic-Induced Evolvable Cell Subpopulation Differentiated by Reactive-Oxygen-Induced General Stress Response
inferred← citeshttps://doi.org/10.1016/j.molcel.2022.07.009openalex-snapshot
Reactive metabolic byproducts contribute to antibiotic lethality under anaerobic conditions
inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.137115openalex-snapshot
Design, synthesis, theoretical studies, and biological activity evaluation of new nitrogen-containing poly heterocyclic compounds as promising antimicrobial agents
inferred← citeshttps://doi.org/10.1016/j.ocecoaman.2022.106173openalex-snapshot
Ecological effects of antibiotics on aquaculture ecosystems based on microbial community in sediments
inferred← citeshttps://doi.org/10.1016/j.pestbp.2026.107209openalex-snapshot
Transcriptomics analysis elucidates the growth inhibitory mechanisms of volatile fungistatic compound 3-ethylbenzaldehyde to Pseudocryphonectria elaeocarpicola
inferred← citeshttps://doi.org/10.1016/j.redox.2021.102164openalex-snapshot
Mitochondrial iron–sulfur clusters: Structure, function, and an emerging role in vascular biology
inferred← citeshttps://doi.org/10.1016/j.resmic.2010.06.004openalex-snapshot
Cysteine biosynthesis, oxidative stress and antibiotic resistance in Salmonella typhimurium
inferred← citeshttps://doi.org/10.1016/j.resmic.2010.09.012openalex-snapshot
Antibiotics promoting oxidative stress inhibit formation of Escherichia coli biofilm via indole signalling
inferred← citeshttps://doi.org/10.1016/j.resmic.2012.06.001openalex-snapshot
Synergistic effect of antimicrobial peptide arenicin-1 in combination with antibiotics against pathogenic bacteria
inferred← citeshttps://doi.org/10.1016/j.resmic.2016.07.008openalex-snapshot
Ciprofloxacin provokes SOS-dependent changes in respiration and membrane potential and causes alterations in the redox status of Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.resmic.2023.104093openalex-snapshot
Evolution of YacG to safeguard DNA gyrase from external perturbation
inferred← citeshttps://doi.org/10.1016/j.rser.2015.12.022openalex-snapshot
Biotechnological and bioinformatics approaches for augmentation of biohydrogen production: A review
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2020.138288openalex-snapshot
Multi-omics analyses reveal molecular mechanisms for the antagonistic toxicity of carbon nanotubes and ciprofloxacin to Escherichia coli
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2023.168916openalex-snapshot
Copper-doped bismuth oxychloride nanosheets assembled into sphere-like morphology for improved photocatalytic inactivation of drug-resistant bacteria
inferred← citeshttps://doi.org/10.1016/j.tim.2012.08.009openalex-snapshot
New-found fundamentals of bacterial persistence
inferred← citeshttps://doi.org/10.1016/j.tim.2014.02.001openalex-snapshot
Molecular mechanisms of antimicrobial tolerance and resistance in bacterial and fungal biofilms
inferred← citeshttps://doi.org/10.1016/j.tim.2016.12.008openalex-snapshot
The Role of Reactive Oxygen Species in Antibiotic-Mediated Killing of Bacteria
inferred← citeshttps://doi.org/10.1016/j.tim.2018.02.004openalex-snapshot
Achieving a Predictive Understanding of Antimicrobial Stress Physiology through Systems Biology
inferred← citeshttps://doi.org/10.1016/j.tiv.2015.06.025openalex-snapshot
Effect of antibiotics on cellular stress generated in Shiga toxin-producing Escherichia coli O157:H7 and non-O157 biofilms
inferred← citeshttps://doi.org/10.1016/j.watres.2026.126533openalex-snapshot
Control of sulfides in gravity sewer pipelines using coated sustained-release granules: Efficiency and mechanisms
inferred← citeshttps://doi.org/10.1016/j.ygeno.2009.01.010openalex-snapshot
Construction of a functional network for common DNA damage responses in Escherichia coli
inferred← citeshttps://doi.org/10.1021/ac200426xopenalex-snapshot
Enhanced Bacterial Biosensor for Fast and Sensitive Detection of Oxidatively DNA Damaging Agents
inferred← citeshttps://doi.org/10.1021/acs.biochem.5c00436openalex-snapshot
Impact of Host and Bacterial Metabolism on Antibiotic Susceptibility
inferred← citeshttps://doi.org/10.1021/acs.chemrestox.8b00038openalex-snapshot
Intact Cell Lipidomics Reveal Changes to the Ratio of Cardiolipins to Phosphatidylinositols in Response to Kanamycin in HeLa and Primary Cells
inferred← citeshttps://doi.org/10.1021/acs.est.1c04641openalex-snapshot
Biological Mitigation of Antibiotic Resistance Gene Dissemination by Antioxidant-Producing Microorganisms in Activated Sludge Systems
inferred← citeshttps://doi.org/10.1021/acs.inorgchem.8b02542openalex-snapshot
Activation by Oxidation: Ferrocene-Functionalized Ru(II)-Arene Complexes with Anticancer, Antibacterial, and Antioxidant Properties
inferred← citeshttps://doi.org/10.1021/acs.jproteome.0c00725openalex-snapshot
Metabolites in the TCA Cycle Promote Resistance to Chloramphenicol of Edwardsiella tarda
inferred← citeshttps://doi.org/10.1021/acsami.3c17424openalex-snapshot
Photo-Responsive Ascorbic Acid-Modified Ag2S–ZnS Heteronanostructure Dropping pH to Trigger Synergistic Antibacterial and Bohr Effects for Accelerating Infected Wound Healing
inferred← citeshttps://doi.org/10.1021/acsinfecdis.0c00317openalex-snapshot
Real-Time Single-Cell Imaging Reveals Accelerating Lipid Peroxyl Radical Formation in Escherichia coli Triggered by a Fluoroquinolone Antibiotic
inferred← citeshttps://doi.org/10.1021/acsinfecdis.4c00880openalex-snapshot
Multifunctional Mycobacterial Topoisomerases with Distinctive Features
inferred← citeshttps://doi.org/10.1021/bi901783sopenalex-snapshot
Localization of the Death Effector Domain of Fas-Associated Death Domain Protein into the Membrane of Escherichia coli Induces Reactive Oxygen Species-Involved Cell Death
inferred← citeshttps://doi.org/10.1021/cr4003984openalex-snapshot
Non-quinolone Inhibitors of Bacterial Type IIA Topoisomerases: A Feat of Bioisosterism
inferred← citeshttps://doi.org/10.1021/jacs.3c10411openalex-snapshot
Redox Active Zn@MOFs as Spontaneous Reactive Oxygen Species Releasing Antimicrobials
inferred← citeshttps://doi.org/10.1021/jacs.9b00394openalex-snapshot
Small Molecule Inhibitors of the BfrB–Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity
inferred← citeshttps://doi.org/10.1021/jacsau.1c00262openalex-snapshot
Targeted Antibacterial Strategy Based on Reactive Oxygen Species Generated from Dioxygen Reduction Using an Organoruthenium Complex
inferred← citeshttps://doi.org/10.1021/jm500462xopenalex-snapshot
Optimization of Pyrrolamide Topoisomerase II Inhibitors Toward Identification of an Antibacterial Clinical Candidate (AZD5099)
inferred← citeshttps://doi.org/10.1038/msb4100184openalex-snapshot
The complexities of antibiotic action
inferred← citeshttps://doi.org/10.1038/nature08184openalex-snapshot
Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans
inferred← citeshttps://doi.org/10.1038/nature09354openalex-snapshot
Bacterial charity work leads to population-wide resistance
inferred← citeshttps://doi.org/10.1038/nature10069openalex-snapshot
Metabolite-enabled eradication of bacterial persisters by aminoglycosides
inferred← citeshttps://doi.org/10.1038/nbt.2458openalex-snapshot
Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production
inferred← citeshttps://doi.org/10.1038/nbt.3011openalex-snapshot
Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
inferred← citeshttps://doi.org/10.1038/nchembio.1380openalex-snapshot
The multiple antibiotic resistance regulator MarR is a copper sensor in Escherichia coli
inferred← citeshttps://doi.org/10.1038/nchembio.590openalex-snapshot
Antibiotics as probes of biological complexity
inferred← citeshttps://doi.org/10.1038/nchembio.740openalex-snapshot
Microbial environments confound antibiotic efficacy
inferred← citeshttps://doi.org/10.1038/nm.2357openalex-snapshot
Peptidoglycan recognition proteins kill bacteria by activating protein-sensing two-component systems
inferred← citeshttps://doi.org/10.1038/nrg2775openalex-snapshot
Synthetic biology: applications come of age
inferred← citeshttps://doi.org/10.1038/nrm3228openalex-snapshot
All tangled up: how cells direct, manage and exploit topoisomerase function
inferred← citeshttps://doi.org/10.1038/nrmicro2333openalex-snapshot
How antibiotics kill bacteria: from targets to networks
inferred← citeshttps://doi.org/10.1038/nrmicro3076openalex-snapshot
A problem of persistence: still more questions than answers?
inferred← citeshttps://doi.org/10.1038/s41467-019-12021-yopenalex-snapshot
Gene networks that compensate for crosstalk with crosstalk
inferred← citeshttps://doi.org/10.1038/s41467-021-22485-6openalex-snapshot
Cytoplasmic condensation induced by membrane damage is associated with antibiotic lethality
inferred← citeshttps://doi.org/10.1038/s41467-021-24434-9openalex-snapshot
Enhanced regulation of prokaryotic gene expression by a eukaryotic transcriptional activator
inferred← citeshttps://doi.org/10.1038/s41467-024-50453-3openalex-snapshot
A synthetic antibiotic class with a deeply-optimized design for overcoming bacterial resistance
inferred← citeshttps://doi.org/10.1038/s41467-024-51347-0openalex-snapshot
Membrane depolarization kills dormant Bacillus subtilis cells by generating a lethal dose of ROS
inferred← citeshttps://doi.org/10.1038/s41467-026-68681-0openalex-snapshot
Differential membrane lipid disruption by lipopeptide antibiotics, colistin and turnercyclamycins
inferred← citeshttps://doi.org/10.1038/s41540-021-00196-4openalex-snapshot
Quantifying the optimal strategy of population control of quorum sensing network in Escherichia coli
inferred← citeshttps://doi.org/10.1038/s41579-020-00443-1openalex-snapshot
Proximate and ultimate causes of the bactericidal action of antibiotics
inferred← citeshttps://doi.org/10.1038/s41598-017-02445-1openalex-snapshot
DNA Backbone Sulfur-Modification Expands Microbial Growth Range under Multiple Stresses by its anti-oxidation function
inferred← citeshttps://doi.org/10.1038/s41598-017-07757-wopenalex-snapshot
Use antibiotics in cell culture with caution: genome-wide identification of antibiotic-induced changes in gene expression and regulation
inferred← citeshttps://doi.org/10.1038/s41598-017-15035-yopenalex-snapshot
Penicillin induces alterations in glutamine metabolism in Streptococcus pneumoniae
inferred← citeshttps://doi.org/10.1038/s41598-019-45070-wopenalex-snapshot
Ctt1 catalase activity potentiates antifungal azoles in the emerging opportunistic pathogen Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1038/s41598-019-53080-xopenalex-snapshot
Silver-coated magnetic nanocomposites induce growth inhibition and protein changes in foodborne bacteria
inferred← citeshttps://doi.org/10.1038/s41598-024-70164-5openalex-snapshot
CRP and IHF act as host regulators in Royal Jelly's antibacterial activity
inferred← citeshttps://doi.org/10.1038/s41598-025-91269-5openalex-snapshot
Analysis of stress response in multiple bacterial pathogens using a network biology approach
inferred← citeshttps://doi.org/10.1038/s42003-021-02074-5openalex-snapshot
Mechanistic insights into synergy between nalidixic acid and tetracycline against clinical isolates of Acinetobacter baumannii and Escherichia coli
inferred← citeshttps://doi.org/10.1038/srep45527openalex-snapshot
Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii
inferred← citeshttps://doi.org/10.1039/c5sc02022kopenalex-snapshot
Interaction of silver atomic quantum clusters with living organisms: bactericidal effect of Ag 3 clusters mediated by disruption of topoisomerase–DNA complexes
inferred← citeshttps://doi.org/10.1039/c6tb03292copenalex-snapshot
A novel nanohybrid for cancer theranostics: folate sensitized Fe 2 O 3 nanoparticles for colorectal cancer diagnosis and photodynamic therapy
inferred← citeshttps://doi.org/10.1039/c9dt03948aopenalex-snapshot
Organometallic ciprofloxacin conjugates with dual action: synthesis, characterization, and antimicrobial and cytotoxicity studies
inferred← citeshttps://doi.org/10.1039/d0cb00218fopenalex-snapshot
Brief survey on organometalated antibacterial drugs and metal-based materials with antibacterial activity
inferred← citeshttps://doi.org/10.1042/bst20190364openalex-snapshot
Bacterial phenotypic heterogeneity in DNA repair and mutagenesis
inferred← citeshttps://doi.org/10.1042/etls20230114openalex-snapshot
The nitric oxide paradox: antimicrobial and inhibitor of antibiotic efficacy
inferred← citeshttps://doi.org/10.1051/bioconf/20201700103openalex-snapshot
Studies on genes expression pattern of antioxidant enzymes and enzymes involved into the genetic information implementation in E.coli cells due to the antibiotic resistance against apramycin and cefatoxime
inferred← citeshttps://doi.org/10.1071/ch11354openalex-snapshot
Instability of Antibacterial Serrulatane Compounds from the Australian Plant Species Eremophila duttonii
inferred← citeshttps://doi.org/10.1073/pnas.0800442106openalex-snapshot
Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy
inferred← citeshttps://doi.org/10.1073/pnas.1009747107openalex-snapshot
Tracking, tuning, and terminating microbial physiology using synthetic riboregulators
inferred← citeshttps://doi.org/10.1073/pnas.1018301108openalex-snapshot
Depletion of antibiotic targets has widely varying effects on growth
inferred← citeshttps://doi.org/10.1073/pnas.1104318108openalex-snapshot
Functional characterization of bacterial sRNAs using a network biology approach
inferred← citeshttps://doi.org/10.1073/pnas.1203735109openalex-snapshot
Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals
inferred← citeshttps://doi.org/10.1073/pnas.1203808109openalex-snapshot
Genetic switchboard for synthetic biology applications
inferred← citeshttps://doi.org/10.1073/pnas.1218274110openalex-snapshot
Iron and citrate export by a major facilitator superfamily pump regulates metabolism and stress resistance in Salmonella Typhimurium
inferred← citeshttps://doi.org/10.1073/pnas.1308085110openalex-snapshot
Salmonella typhimurium intercepts Escherichia coli signaling to enhance antibiotic tolerance
inferred← citeshttps://doi.org/10.1073/pnas.1315954111openalex-snapshot
Programmed Allee effect in bacteria causes a tradeoff between population spread and survival
inferred← citeshttps://doi.org/10.1073/pnas.1400093111openalex-snapshot
Enhanced killing of antibiotic-resistant bacteria enabled by massively parallel combinatorial genetics
inferred← citeshttps://doi.org/10.1073/pnas.1401876111openalex-snapshot
Antibiotics induce redox-related physiological alterations as part of their lethality
inferred← citeshttps://doi.org/10.1073/pnas.1425007112openalex-snapshot
Generation of reactive oxygen species by lethal attacks from competing microbes
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