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Atelocollagen-mediated Systemic Delivery Prevents Immunostimulatory Adverse Effects of siRNA in Mammals
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/cncr.22068openalex-snapshot
Combinational antitumor effect of siRNA against midkine and paclitaxel on growth of human prostate cancer xenografts
inferredcites →https://doi.org/10.1002/eji.200535708openalex-snapshot
Single‐stranded small interfering RNA are more immunostimulatory than their double‐stranded counterparts: A central role for 2′‐hydroxyl uridines in immune responses
inferredcites →https://doi.org/10.1002/ijc.24382openalex-snapshot
Systemic delivery of siRNA specific to tumor mediated by atelocollagen: Combined therapy using siRNA targeting Bcl‐xL and cisplatin against prostate cancer
inferredcites →https://doi.org/10.1007/s00403-001-0276-9openalex-snapshot
The role of chemokines in allergic contact dermatitis
inferredcites →https://doi.org/10.1016/j.bbrc.2007.06.177openalex-snapshot
Suppression of immunostimulatory siRNA-driven innate immune activation by 2′-modified RNAs
inferredcites →https://doi.org/10.1016/j.bbrc.2010.07.045openalex-snapshot
Knockdown of Akt isoforms by RNA silencing suppresses the growth of human prostate cancer cells in vitro and in vivo
inferredcites →https://doi.org/10.1016/j.immuni.2005.06.008openalex-snapshot
Suppression of RNA Recognition by Toll-like Receptors: The Impact of Nucleoside Modification and the Evolutionary Origin of RNA
inferredcites →https://doi.org/10.1016/j.jvs.2006.04.044openalex-snapshot
Controlled release of small interfering RNA targeting midkine attenuates intimal hyperplasia in vein grafts
inferredcites →https://doi.org/10.1016/j.ymthe.2006.06.001openalex-snapshot
siRNA and isRNA: two edges of one sword
inferredcites →https://doi.org/10.1016/s0002-9440(10)63986-7openalex-snapshot
Differential and Sequential Expression of Multiple Chemokines during Elicitation of Allergic Contact Hypersensitivity
inferredcites →https://doi.org/10.1016/s0165-2478(03)00017-8openalex-snapshot
Kinetic profiles of sequential gene expressions for chemokines in mice with contact hypersensitivity
inferredcites →https://doi.org/10.1016/s0167-5699(97)01186-9openalex-snapshot
Immunoregulatory mechanisms involved in elicitation of allergic contact hypersensitivity
inferredcites →https://doi.org/10.1038/35078107openalex-snapshot
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
inferredcites →https://doi.org/10.1038/35888openalex-snapshot
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
inferredcites →https://doi.org/10.1038/9560openalex-snapshot
New delivery system for plasmid DNA in vivo using atelocollagen as a carrier material: the Minipellet
inferredcites →https://doi.org/10.1038/mt.2009.207openalex-snapshot
Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes
inferredcites →https://doi.org/10.1038/nature07758openalex-snapshot
The promises and pitfalls of RNA-interference-based therapeutics
inferredcites →https://doi.org/10.1038/nbt1081openalex-snapshot
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
inferredcites →https://doi.org/10.1038/nbt1161openalex-snapshot
Activation of the mammalian immune system by siRNAs
inferredcites →https://doi.org/10.1038/ncb1038openalex-snapshot
Activation of the interferon system by short-interfering RNAs
inferredcites →https://doi.org/10.1038/ng1173openalex-snapshot
Induction of an interferon response by RNAi vectors in mammalian cells
inferredcites →https://doi.org/10.1038/nm.1858openalex-snapshot
RPN2 gene confers docetaxel resistance in breast cancer
inferredcites →https://doi.org/10.1038/nm.1887openalex-snapshot
5′-triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma
inferredcites →https://doi.org/10.1038/nm1191openalex-snapshot
Sequence-specific potent induction of IFN-α by short interfering RNA in plasmacytoid dendritic cells through TLR7
inferredcites →https://doi.org/10.1038/nri2314openalex-snapshot
Interferon-inducible antiviral effectors
inferredcites →https://doi.org/10.1038/nri2448openalex-snapshot
Exploring the full spectrum of macrophage activation
inferredcites →https://doi.org/10.1038/sj.mt.6300240openalex-snapshot
2′-O-methyl-modified RNAs Act as TLR7 Antagonists
inferredcites →https://doi.org/10.1038/sj.mt.6300360openalex-snapshot
Downregulation of Monocyte Chemoattractant Protein-1 Involving Short Interfering RNA Attenuates Hapten-induced Contact Hypersensitivity
inferredcites →https://doi.org/10.1046/j.1365-2567.2002.01474.xopenalex-snapshot
The modulatory effects of prostaglandin‐E on cytokine production by human peripheral blood mononuclear cells are independent of the prostaglandin subtype
inferredcites →https://doi.org/10.1073/pnas.0501753102openalex-snapshot
Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo
inferredcites →https://doi.org/10.1074/jbc.m501155200openalex-snapshot
Endo180 Binds to the C-terminal Region of Type I Collagen
inferredcites →https://doi.org/10.1089/hum.2007.179openalex-snapshot
Overcoming the Innate Immune Response to Small Interfering RNA
inferredcites →https://doi.org/10.1089/hum.2008.131openalex-snapshot
Misinterpreting the Therapeutic Effects of Small Interfering RNA Caused by Immune Stimulation
inferredcites →https://doi.org/10.1091/mbc.e02-12-0814openalex-snapshot
Identification and Characterization of the Endocytic Transmembrane Glycoprotein Endo180 as a Novel Collagen Receptor
inferredcites →https://doi.org/10.1093/nar/gkp714openalex-snapshot
Short-hairpin RNAs delivered by lentiviral vector transduction trigger RIG-I-mediated IFN activation
inferredcites →https://doi.org/10.1093/nar/gnh093openalex-snapshot
Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
inferredcites →https://doi.org/10.1158/0008-5472.can-03-2682openalex-snapshot
A Small Interfering RNA Targeting Vascular Endothelial Growth Factor as Cancer Therapeutics
inferredcites →https://doi.org/10.1158/0008-5472.can-06-3496openalex-snapshot
The Collagen Receptor Endo180 (CD280) Is Expressed on Basal-like Breast Tumor Cells and Promotes Tumor Growth In vivo
inferredcites →https://doi.org/10.1158/1535-7163.mct-08-0473openalex-snapshot
Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer
inferredcites →https://doi.org/10.1172/jci200523043openalex-snapshot
Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer
inferredcites →https://doi.org/10.1172/jci37155openalex-snapshot
Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon–independent apoptosis in human melanoma cells
inferredcites →https://doi.org/10.1242/jcs.113.6.1021openalex-snapshot
Endo180, an endocytic recycling glycoprotein related to the macrophage mannose receptor is expressed on fibroblasts, endothelial cells and macrophages and functions as a lectin receptor
inferredcites →https://doi.org/10.22203/ecm.v020a16openalex-snapshot
Endo180 and MT1-MMP are involved in the phagocytosis of collagen scaffolds by macrophages and is regulated by interferon-gamma
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4797381openalex-extracted
Delivery of microRNA-122-5p via a Novel Nanoparticle Delivery Vehicle Reduces Inflammation in a Rat Articular Chondrocyte Model of Osteoarthritis
inferred← citeshttps://doi.org/10.1002/adhm.202304675openalex-snapshot
Layer‐by‐Layer Assembly of Renal‐Targeted Polymeric Nanoparticles for Robust Arginase‐2 Knockdown and Contrast‐Induced Acute Kidney Injury Prevention
inferred← citeshttps://doi.org/10.1002/jps.23300openalex-snapshot
Formulation Approaches to Short Interfering RNA and MicroRNA: Challenges and Implications
inferred← citeshttps://doi.org/10.1007/978-1-4939-9220-1_3openalex-snapshot
siRNA-Based Drug Targeting Human Bcl-xL Against Cancers
inferred← citeshttps://doi.org/10.1007/s13277-014-2477-9openalex-snapshot
Therapeutic potential of siRNA and DNAzymes in cancer
inferred← citeshttps://doi.org/10.1016/j.addr.2016.05.010openalex-snapshot
Delivery strategies and potential targets for siRNA in major cancer types
inferred← citeshttps://doi.org/10.1016/j.ajps.2023.100845openalex-snapshot
The emerging potential of siRNA nanotherapeutics in treatment of arthritis
inferred← citeshttps://doi.org/10.1016/j.bbagen.2016.04.005openalex-snapshot
A therapeutic trial of human melanomas with combined small interfering RNAs targeting adaptor molecules p130Cas and paxillin activated under expression of ganglioside GD3
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2022.121562openalex-snapshot
Modified chitosan for effective renal delivery of siRNA to treat acute kidney injury
inferred← citeshttps://doi.org/10.1016/j.canlet.2013.09.023openalex-snapshot
Polycation-based nanoparticles for RNAi-mediated cancer treatment
inferred← citeshttps://doi.org/10.1016/j.isci.2026.115163openalex-snapshot
Progress in siRNA therapy and delivery platforms for osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.jconrel.2021.11.029openalex-snapshot
Preferential siRNA delivery to injured kidneys for combination treatment of acute kidney injury
inferred← citeshttps://doi.org/10.1038/labinvest.2017.4openalex-snapshot
Sodium chloride promotes tissue inflammation via osmotic stimuli in subtotal-nephrectomized mice
inferred← citeshttps://doi.org/10.1038/mt.2012.190openalex-snapshot
Nonviral Delivery of Small Interfering RNA Into Pancreas-associated Immune Cells Prevents Autoimmune Diabetes
inferred← citeshttps://doi.org/10.1038/mt.2013.288openalex-snapshot
A Collagen-based Scaffold Delivering Exogenous MicroRNA-29B to Modulate Extracellular Matrix Remodeling
inferred← citeshttps://doi.org/10.1038/nrd4685openalex-snapshot
Clinical experiences with systemically administered siRNA-based therapeutics in cancer
inferred← citeshttps://doi.org/10.1039/9781782620105-00268openalex-snapshot
Cationic Polymer Nanoparticles for Drug and Gene Delivery
inferred← citeshttps://doi.org/10.1073/pnas.1411393111openalex-snapshot
Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA
inferred← citeshttps://doi.org/10.1083/jcb.201503113openalex-snapshot
AMIGO2, a novel membrane anchor of PDK1, controls cell survival and angiogenesis via Akt activation
inferred← citeshttps://doi.org/10.1089/nat.2014.0526openalex-snapshot
Atelocollagen-Mediated Intravenous siRNA Delivery Specific to Tumor Tissues Orthotopically Xenografted in Prostates of Nude Mice and Its Anticancer Effects
inferred← citeshttps://doi.org/10.1159/000354092openalex-snapshot
Efficient Delivery of siRNA by Atelocollagen in a Murine Laser-Induced Choroidal Neovascularization Model
inferred← citeshttps://doi.org/10.1159/000488801openalex-snapshot
MicroRNAs Associated with Epithelial-Mesenchymal Transition Can Be Targeted to Inhibit Peritoneal Dissemination of Human Scirrhous Gastric Cancers
inferred← citeshttps://doi.org/10.1159/000508350openalex-snapshot
Long Noncoding RNA HOTAIR Promotes Epithelial-Mesenchymal Transition and Is a Suitable Target to Inhibit Peritoneal Dissemination in Human Scirrhous Gastric Cancers
inferred← citeshttps://doi.org/10.11606/t.5.2016.tde-22082016-104926openalex-snapshot
O uso de microRNA para tratamento do câncer de próstata: estudos in vitro e in vivo
inferred← citeshttps://doi.org/10.1186/s12885-016-2467-yopenalex-snapshot
Tumor-suppressive effects of atelocollagen-conjugated hsa-miR-520d-5p on un-differentiated cancer cells in a mouse xenograft model
inferred← citeshttps://doi.org/10.1186/s12931-015-0310-7openalex-snapshot
RNA interference targeting carbohydrate sulfotransferase 3 diminishes macrophage accumulation, inhibits MMP-9 expression and promotes lung recovery in murine pulmonary emphysema
inferred← citeshttps://doi.org/10.1186/s12951-025-03338-6openalex-snapshot
Autologous platelet delivery of siRNAs by autologous plasma protein self-assembled nanoparticles for the treatment of acute kidney injury
inferred← citeshttps://doi.org/10.1186/s13046-016-0334-yopenalex-snapshot
Sustained delivery of siRNA/PEI complex from in situ forming hydrogels potently inhibits the proliferation of gastric cancer
inferred← citeshttps://doi.org/10.1186/s42825-025-00223-8openalex-snapshot
Applications of nanomaterials in the diagnosis and treatment of thyroid disorders
inferred← citeshttps://doi.org/10.14193/jkfas.2023.27.4.117openalex-snapshot
Understanding Atelocollagen Injections for Patients with Foot and Ankle Diseases
inferred← citeshttps://doi.org/10.1517/17425247.2014.866089openalex-snapshot
High-density lipoproteins for the systemic delivery of short interfering RNA
inferred← citeshttps://doi.org/10.15761/imm.1000364openalex-snapshot
A novel anti-cancer effect of atelocollagen-conjugated miR-520d-5p on pancreatic cancer cells in vitro and in a mouse xenograft model
inferred← citeshttps://doi.org/10.20381/ruor-23588openalex-snapshot
Administration of Human Endothelial Colony Forming Cell-Derived Exosomes and miR-486-5p Protects Against Ischemia/Reperfusion Acute Kidney Injury
inferred← citeshttps://doi.org/10.21182/jmisst.2022.00577openalex-snapshot
A Clinical Pilot Study Showing the Safety and Efficacy of Intramuscular Injection of Atelocollagen for Prevention of Paraspinal Muscle Atrophy after Spine Surgery
inferred← citeshttps://doi.org/10.3389/fgene.2012.00154openalex-snapshot
Development of Therapeutic-Grade Small Interfering RNAs by Chemical Engineering
inferred← citeshttps://doi.org/10.3389/fmolb.2026.1785592openalex-snapshot
Efficiency and safety of five different agents for in vivo delivery of novel bioengineered RNAi molecules
inferred← citeshttps://doi.org/10.3390/biom16060858openalex-snapshot
m6A RNA Methylation-miRNA Crosstalk in Cardiovascular Remodeling
inferred← citeshttps://doi.org/10.3390/jcm13175241openalex-snapshot
An Evaluation of Skin and Immunological Responses after Using a Novel Cross-Linked Porcine-Based Dermal Injectable Collagen with Lidocaine for Nasolabial Fold Correction
inferred← citeshttps://doi.org/10.3390/life10070114openalex-snapshot
Atelocollagen Application in Human Periodontal Tissue Treatment—A Pilot Study
inferred← citeshttps://doi.org/10.3390/ph6070881openalex-snapshot
New Aspects of Gene-Silencing for the Treatment of Cardiovascular Diseases
inferred← citeshttps://doi.org/10.3892/ijo.2014.2789openalex-snapshot
Usefulness of microRNA-375 as a prognostic and therapeutic tool in esophageal squamous cell carcinoma
inferred← citeshttps://doi.org/10.4155/tde.14.8openalex-snapshot
Atelocollagen-Mediated siRNA Delivery: Future Promise for Therapeutic Application
inferred← citeshttps://doi.org/10.70675/e91475a6z3b26z42ecza153zdc13a97fb5ecopenalex-snapshot
Signalisation et ciblage thérapeutique du récepteur tyrosine kinase AXL dans les cancers
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