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Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Amphoteric liposomes enable systemic antigen‐presenting cell–directed delivery of CD40 antisense and are therapeutically effective in experimental arthritis
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Modulation of c‐Met signaling and cellular sensitivity to radiation
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miR‐200c enhances radiosensitivity of human breast cancer cells
inferredcites →https://doi.org/10.1016/0167-8140(91)90053-jopenalex-snapshot
A linear-quadratic model of cell survival considering both sublethal and potentially lethal radiation damage
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Transcription factor GABP/NRF-2 controlling biogenesis of mitochondria regulates basal expression of peroxiredoxin V but the mitochondrial function of peroxiredoxin V is dispensable in the dog
inferredcites →https://doi.org/10.1016/j.cell.2004.12.035openalex-snapshot
Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets
inferredcites →https://doi.org/10.1016/j.cell.2009.04.021openalex-snapshot
Therapeutic microRNA Delivery Suppresses Tumorigenesis in a Murine Liver Cancer Model
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The Ets Transcription Factor GABP Is a Component of the Hippo Pathway Essential for Growth and Antioxidant Defense
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Decreasing peroxiredoxin II expression decreases glutathione, alters cell cycle distribution, and sensitizes glioma cells to ionizing radiation and H2O2
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Phase II Study of Erlotinib with Concurrent Whole-brain Radiation Therapy for Patients with Brain Metastases from Non-small Cell Lung Cancer
inferredcites →https://doi.org/10.1016/j.jbi.2011.05.002openalex-snapshot
miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes
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Peroxiredoxin II Is an Essential Antioxidant Enzyme that Prevents the Oxidative Inactivation of VEGF Receptor-2 in Vascular Endothelial Cells
inferredcites →https://doi.org/10.1016/j.yjmcc.2004.06.017openalex-snapshot
The essential role of p21 in radiation-induced cell cycle arrest of vascular smooth muscle cell
inferredcites →https://doi.org/10.1016/s0140-6736(09)60569-9openalex-snapshot
Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial
inferredcites →https://doi.org/10.1038/cdd.2011.42openalex-snapshot
miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition
inferredcites →https://doi.org/10.1038/embor.2008.74openalex-snapshot
A reciprocal repression between ZEB1 and members of the miR‐200 family promotes EMT and invasion in cancer cells
inferredcites →https://doi.org/10.1038/embor.2010.117openalex-snapshot
The ZEB/miR‐200 feedback loop—a motor of cellular plasticity in development and cancer?
inferredcites →https://doi.org/10.1038/mt.2009.207openalex-snapshot
Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes
inferredcites →https://doi.org/10.1038/mt.2011.48openalex-snapshot
Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice
inferredcites →https://doi.org/10.1038/nature02075openalex-snapshot
ATP-dependent reduction of cysteine–sulphinic acid by S. cerevisiae sulphiredoxin
inferredcites →https://doi.org/10.1038/nature03702openalex-snapshot
MicroRNA expression profiles classify human cancers
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The Ets transcription factor GABP is required for cell-cycle progression
inferredcites →https://doi.org/10.1038/ncb1722openalex-snapshot
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
inferredcites →https://doi.org/10.1038/ncomms3427openalex-snapshot
Tumour angiogenesis regulation by the miR-200 family
inferredcites →https://doi.org/10.1038/nm.2512openalex-snapshot
miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
inferredcites →https://doi.org/10.1038/onc.2012.93openalex-snapshot
Peroxiredoxin 2 specifically regulates the oxidative and metabolic stress response of human metastatic breast cancer cells in lungs
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Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability
inferredcites →https://doi.org/10.1073/pnas.0805507105openalex-snapshot
A redox-sensitive peroxiredoxin that is important for longevity has tissue- and stress-specific roles in stress resistance
inferredcites →https://doi.org/10.1074/jbc.c800074200openalex-snapshot
The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2
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Inhibition of p21‐mediated ROS accumulation can rescue p21‐induced senescence
inferredcites →https://doi.org/10.1093/nar/gkr646openalex-snapshot
The microRNA body map: dissecting microRNA function through integrative genomics
inferredcites →https://doi.org/10.1096/fj.10-155762openalex-snapshot
p21cip/WAFis a key regulator of long-term radiation damage in mesenchyme-derived tissues
inferredcites →https://doi.org/10.1101/gad.1640608openalex-snapshot
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
inferredcites →https://doi.org/10.1111/j.1742-4658.2006.05265.xopenalex-snapshot
Constitutive expression of the human peroxiredoxin V gene contributes to protection of the genome from oxidative DNA lesions and to suppression of transcription of noncoding DNA
inferredcites →https://doi.org/10.1126/science.1095569openalex-snapshot
Regeneration of Peroxiredoxins by p53-Regulated Sestrins, Homologs of Bacterial AhpD
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Mechanisms of Enhanced Radiation Response following Epidermal Growth Factor Receptor Signaling Inhibition by Erlotinib (Tarceva)
inferredcites →https://doi.org/10.1158/1541-7786.mcr-10-0052openalex-snapshot
Loss of miR-200c Expression Induces an Aggressive, Invasive, and Chemoresistant Phenotype in Non–Small Cell Lung Cancer
inferredcites →https://doi.org/10.1200/jco.2011.40.1174openalex-snapshot
Phase II Trial of Erlotinib Plus Concurrent Whole-Brain Radiation Therapy for Patients With Brain Metastases From Non–Small-Cell Lung Cancer
inferredcites →https://doi.org/10.1371/journal.pone.0078344openalex-snapshot
MiR-200c Increases the Radiosensitivity of Non-Small-Cell Lung Cancer Cell Line A549 by Targeting VEGF-VEGFR2 Pathway
inferredcites →https://doi.org/10.3389/fgene.2012.00120openalex-snapshot
miR-34 – a microRNA replacement therapy is headed to the clinic
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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miR-200c Modulates the Pathogenesis of Radiation-Induced Oral Mucositis
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Long Noncoding RNAs and Circular RNAs in the Metabolic Reprogramming of Lung Cancer: Functions, Mechanisms, and Clinical Potential
inferred← citeshttps://doi.org/10.1158/0008-5472.can-19-1807openalex-snapshot
Therapeutic Potential of the miRNA–ATM Axis in the Management of Tumor Radioresistance
inferred← citeshttps://doi.org/10.1177/0271678x18773871openalex-snapshot
MicroRNA-based therapeutics in central nervous system injuries
inferred← citeshttps://doi.org/10.1186/s11658-024-00632-3openalex-snapshot
MicroRNAs in metabolism for precision treatment of lung cancer
inferred← citeshttps://doi.org/10.1186/s12885-019-5337-6openalex-snapshot
Encapsulated miR-200c and Nkx2.1 in a nuclear/mitochondria transcriptional regulatory network of non-metastatic and metastatic lung cancer cells
inferred← citeshttps://doi.org/10.1186/s12933-020-01107-3openalex-snapshot
MicroRNAs and obesity-induced endothelial dysfunction: key paradigms in molecular therapy
inferred← citeshttps://doi.org/10.1186/s12935-023-03203-2openalex-snapshot
Non-coding RNAs as potential therapeutic targets for receptor tyrosine kinase signaling in solid tumors: current status and future directions
inferred← citeshttps://doi.org/10.1186/s12935-024-03430-1openalex-snapshot
The interplay between microRNAs and Nrf2 signaling in human cancers
inferred← citeshttps://doi.org/10.1186/s12935-024-03549-1openalex-snapshot
Comprehensive review of LncRNA-mediated therapeutic resistance in non-small cell lung cancer
inferred← citeshttps://doi.org/10.1186/s12967-017-1357-7openalex-snapshot
Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer
inferred← citeshttps://doi.org/10.1186/s13045-015-0162-0openalex-snapshot
MiRNA-based therapeutic intervention of cancer
inferred← citeshttps://doi.org/10.1186/s41544-019-0026-9openalex-snapshot
microRNAs as therapeutic targets in intestinal diseases
inferred← citeshttps://doi.org/10.13052/mct2052-8426.811openalex-snapshot
Clinical Potential of miRNAs in Human and Infectious Diseases
inferred← citeshttps://doi.org/10.1371/journal.pone.0136058openalex-snapshot
Epstein-Barr Virus MicroRNA Expression Increases Aggressiveness of Solid Malignancies
inferred← citeshttps://doi.org/10.1371/journal.pone.0173401openalex-snapshot
Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods
inferred← citeshttps://doi.org/10.15252/embj.2021108647openalex-snapshot
Dynamic EMT: a multi‐tool for tumor progression
inferred← citeshttps://doi.org/10.17179/excli2017-721openalex-snapshot
In vitro transfection of anti-tumor miR-101 induces BIM, a pro-apoptotic protein, expression in acute myeloid leukemia (AML)
inferred← citeshttps://doi.org/10.17219/acem/135478openalex-snapshot
Baicalein modulates the radiosensitivity of cervical cancer cells in vitro via miR-183 and the JAK2/STAT3 signaling pathway
inferred← citeshttps://doi.org/10.18632/oncotarget.15680openalex-snapshot
microRNA-200c/141 upregulates SerpinB2 to promote breast cancer cell metastasis and reduce patient survival
inferred← citeshttps://doi.org/10.18632/oncotarget.3052openalex-snapshot
The microRNA-200 family: small molecules with novel roles in cancer development, progression and therapy
inferred← citeshttps://doi.org/10.20517/2394-4722.2025.108openalex-snapshot
Functional significance of miR-218 in lung cancer
inferred← citeshttps://doi.org/10.20935/acadonco7887openalex-snapshot
MicroRNA-mediated regulation of autophagy in lung cancer: role in tumourigenesis and chemotherapy resistance
inferred← citeshttps://doi.org/10.20944/preprints202310.1943.v1openalex-snapshot
Epigenetic Signatures of In Vitro and In Vivo Experimental Models Employed in Non-small Cell Lung Cancer and the Unique miR-148b-3p/PVT1/ZBTB7A Regulatory Network Discriminating Large Cell Lung Carcinoma
inferred← citeshttps://doi.org/10.2147/dddt.s156635openalex-snapshot
Anticancer activity of the intraperitoneal-delivered DFP-10825, the cationic liposome-conjugated RNAi molecule targeting thymidylate synthase, on peritoneal disseminated ovarian cancer xenograft model
inferred← citeshttps://doi.org/10.2147/dmso.s298950openalex-snapshot
Atorvastatin Regulates MALAT1/miR-200c/NRF2 Activity to Protect Against Podocyte Pyroptosis Induced by High Glucose
inferred← citeshttps://doi.org/10.2147/ott.s311567openalex-snapshot
Carbon-Ion Beam Irradiation and the miR-200c Mimic Effectively Eradicate Pancreatic Cancer Stem Cells Under in vitro and in vivo Conditions
inferred← citeshttps://doi.org/10.2174/0929867328666210810160901openalex-snapshot
Recent Advances in Lung Cancer Therapy Based on Nanomaterials: A Review
inferred← citeshttps://doi.org/10.2174/1381612823666170714150118openalex-snapshot
Role of miRNA in Lung Cancer-Potential Biomarkers and Therapies
inferred← citeshttps://doi.org/10.2174/1389557515666150709115355openalex-snapshot
MicroRNAs Used in Combination with Anti-Cancer Treatments Can Enhance Therapy Efficacy
inferred← citeshttps://doi.org/10.2174/2211536608666190919161849openalex-snapshot
MicroRNAs Determining Carcinogenesis by Regulating Oncogenes and Tumor Suppressor Genes During Cell Cycle
inferred← citeshttps://doi.org/10.2217/epi-2016-0035openalex-snapshot
Clinical Development of TargomiRs, a miRNA Mimic-Based Treatment for Patients with Recurrent Thoracic Cancer
inferred← citeshttps://doi.org/10.22270/jddt.v15i8.7336openalex-snapshot
Biogenesis and implication of miRNAs in the development of diseases and their theranostic inhibitions
inferred← citeshttps://doi.org/10.24377/researchonline.ljmu.ac.uk.00009376openalex-snapshot
MicroRNA Nanocarriers for the Treatment of Chronic Obstructive Pulmonary Disease
inferred← citeshttps://doi.org/10.26600/mollife.1.1.6.2017openalex-snapshot
MicroRNas: beating cancer with new powerful weapons
inferred← citeshttps://doi.org/10.3389/fbinf.2026.1876523openalex-snapshot
Radiation-induced network rewiring in cancer: systems-level insights into environmental radioactivity and precision oncology
inferred← citeshttps://doi.org/10.3389/fimmu.2017.01106openalex-snapshot
Translational Significance for Tumor Metastasis of Tumor-Associated Macrophages and Epithelial–Mesenchymal Transition
inferred← citeshttps://doi.org/10.3389/fimmu.2018.00546openalex-snapshot
MicroRNA Roles in the Nuclear Factor Kappa B Signaling Pathway in Cancer
inferred← citeshttps://doi.org/10.3389/fmed.2020.603047openalex-snapshot
Non-coding RNAs as Regulators of Cellular Senescence in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease
inferred← citeshttps://doi.org/10.3389/fonc.2019.00054openalex-snapshot
Activation of Epithelial-Mesenchymal Transition and Altered β-Catenin Signaling in a Novel Indian Colorectal Carcinoma Cell Line
inferred← citeshttps://doi.org/10.3389/fonc.2021.679348openalex-snapshot
Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and Contributes to the Effect of Cisplatin
inferred← citeshttps://doi.org/10.3389/fonc.2021.708765openalex-snapshot
Tumor Suppressor miRNA in Cancer Cells and the Tumor Microenvironment: Mechanism of Deregulation and Clinical Implications
inferred← citeshttps://doi.org/10.3389/fonc.2025.1677471openalex-snapshot
MicroRNAs and lung cancer: overview of essential pathways and somatic mutations in cancer progression
inferred← citeshttps://doi.org/10.3389/fphar.2020.596239openalex-snapshot
Tackle Epithelial-Mesenchymal Transition With Epigenetic Drugs in Cancer
inferred← citeshttps://doi.org/10.3389/fphar.2022.924817openalex-snapshot
Epigenetic Therapeutics Targeting NRF2/KEAP1 Signaling in Cancer Oxidative Stress
inferred← citeshttps://doi.org/10.3389/fphar.2022.944773openalex-snapshot
Engaging plasticity: Differentiation therapy in solid tumors
inferred← citeshttps://doi.org/10.3390/biology11030349openalex-snapshot
MicroRNA-200c Attenuates the Tumor-Infiltrating Capacity of Macrophages
inferred← citeshttps://doi.org/10.3390/biom12060781openalex-snapshot
Revisiting the miR-200 Family: A Clan of Five Siblings with Essential Roles in Development and Disease
inferred← citeshttps://doi.org/10.3390/biom13060877openalex-snapshot
MiRNA-Based Therapies for Lung Cancer: Opportunities and Challenges?
inferred← citeshttps://doi.org/10.3390/cancers12071852openalex-snapshot
A Comprehensive Review of Cancer MicroRNA Therapeutic Delivery Strategies
inferred← citeshttps://doi.org/10.3390/cancers12113454openalex-snapshot
Integrative p53, micro-RNA and Cathepsin Protease Co-Regulatory Expression Networks in Cancer
inferred← citeshttps://doi.org/10.3390/cancers13010012openalex-snapshot
Pathogenetic Role and Clinical Implications of Regulatory RNAs in Biliary Tract Cancer
inferred← citeshttps://doi.org/10.3390/cancers13071716openalex-snapshot
The Role of MicroRNAs in Lung Cancer Metabolism
inferred← citeshttps://doi.org/10.3390/cancers13112680openalex-snapshot
MicroRNA Therapeutics in Cancer: Current Advances and Challenges
inferred← citeshttps://doi.org/10.3390/cells11061008openalex-snapshot
MicroRNA as a Potential Therapeutic Molecule in Cancer
inferred← citeshttps://doi.org/10.3390/cells11152332openalex-snapshot
MicroRNAs and Their Big Therapeutic Impacts: Delivery Strategies for Cancer Intervention
inferred← citeshttps://doi.org/10.3390/diagnostics12071610openalex-snapshot
MiRNAs in Lung Cancer: Diagnostic, Prognostic, and Therapeutic Potential
inferred← citeshttps://doi.org/10.3390/ijms16035254openalex-snapshot
Development of Small RNA Delivery Systems for Lung Cancer Therapy
inferred← citeshttps://doi.org/10.3390/ijms17050773openalex-snapshot
Predicting MicroRNA Biomarkers for Cancer Using Phylogenetic Tree and Microarray Analysis
inferred← citeshttps://doi.org/10.3390/ijms18061207openalex-snapshot
The Functions of MicroRNA-200 Family in Ovarian Cancer: Beyond Epithelial-Mesenchymal Transition
inferred← citeshttps://doi.org/10.3390/ijms18102079openalex-snapshot
The Role and Mechanism of Epithelial-to-Mesenchymal Transition in Prostate Cancer Progression
inferred← citeshttps://doi.org/10.3390/ijms20071611openalex-snapshot
The Roles of MicroRNA in Lung Cancer
inferred← citeshttps://doi.org/10.3390/ijms20215335openalex-snapshot
The Yin-Yang Regulation of Reactive Oxygen Species and MicroRNAs in Cancer
inferred← citeshttps://doi.org/10.3390/ijms21165904openalex-snapshot
Recent Progress on Relevant microRNAs in Autism Spectrum Disorders
inferred← citeshttps://doi.org/10.3390/ijms21217872openalex-snapshot
New Insights into Therapy-Induced Progression of Cancer
inferred← citeshttps://doi.org/10.3390/ijms21228782openalex-snapshot
Diagnostic and Therapeutic Implications of microRNAs in Non-Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.3390/ijms22042210openalex-snapshot
Therapeutic Targeting of MicroRNAs in the Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/ijms22105247openalex-snapshot
BMAL1 Knockdown Leans Epithelial–Mesenchymal Balance toward Epithelial Properties and Decreases the Chemoresistance of Colon Carcinoma Cells
inferred← citeshttps://doi.org/10.3390/ijms22116022openalex-snapshot
Micro RNAs in Regulation of Cellular Redox Homeostasis
inferred← citeshttps://doi.org/10.3390/ijms24076121openalex-snapshot
The Small RNA Landscape in NSCLC: Current Therapeutic Applications and Progresses
inferred← citeshttps://doi.org/10.3390/mps4010010openalex-snapshot
Recent Advances in miRNA Delivery Systems
inferred← citeshttps://doi.org/10.3390/nu16213658openalex-snapshot
The Role of Exogenous microRNAs on Human Health: The Plant–Human Trans-Kingdom Hypothesis
inferred← citeshttps://doi.org/10.3390/ph18060784openalex-snapshot
Redox Imbalance in Cystic Fibrosis: The Multifaceted Role of Oxidative Stress
inferred← citeshttps://doi.org/10.3390/toxics13121021openalex-snapshot
Serum miRNA and Metabolomic Signatures of Residential Radon Exposure in Chiang Mai, Thailand
inferred← citeshttps://doi.org/10.3892/ijo.2016.3503openalex-snapshot
Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: New trends in the development of miRNA therapeutic strategies in oncology (Review)
inferred← citeshttps://doi.org/10.3892/mmr.2022.12878openalex-snapshot
Long non‑coding RNAs and microRNAs as regulators of stress in cancer (Review)
inferred← citeshttps://doi.org/10.3892/ol.2017.5701openalex-snapshot
MicroRNA-124 regulates the radiosensitivity of non-small cell lung cancer cells by targeting TXNRD1
inferred← citeshttps://doi.org/10.3892/or.2015.3982openalex-snapshot
Tangeretin enhances radiosensitivity and inhibits the radiation-induced epithelial-mesenchymal transition of gastric cancer cells
inferred← citeshttps://doi.org/10.3892/or.2017.5888openalex-snapshot
Potential role of ZEB1 as a DNA repair regulator in colorectal cancer cells revealed by cancer-associated promoter profiling
inferred← citeshttps://doi.org/10.3892/or.2018.6925openalex-snapshot
MicroRNA‑200a suppresses migration and invasion and enhances the radiosensitivity of NSCLC cells by inhibiting the HGF/c‑Met signaling pathway
inferred← citeshttps://doi.org/10.5772/intechopen.107930openalex-snapshot
Role of Non-Coding RNAs in Lung Cancer
inferred← citeshttps://doi.org/10.70675/f9bc8234z71f7z4d14z88f2zf9c8dcdf114fopenalex-snapshot
Circadian clocks and cancer : The implication of BMAL1 (brain and muscle Arnt-like protein-1) in colorectal and breast carcinoma development and treatment
inferred← citeshttps://doi.org/10.7150/ijbs.22243openalex-snapshot
MicroRNAs associated with therapy of non-small cell lung cancer
inferred← citeshttps://doi.org/10.7150/thno.45253openalex-snapshot
Epigenetic repression of miR-17 contributed to di(2-ethylhexyl) phthalate-triggered insulin resistance by targeting Keap1-Nrf2/miR-200a axis in skeletal muscle
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