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FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left–right determination
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/0006-8993(92)91557-uopenalex-snapshot
Chronological expression of microtubule-associated proteins (MAPs) in EC cell P19 after neuronal induction by retinoic acid
inferredcites →https://doi.org/10.1016/0076-6879(93)25013-ropenalex-snapshot
[10] Isolation and culture of whole postimplantation embryos and germ layer derivatives
inferredcites →https://doi.org/10.1016/s0092-8674(00)81437-3openalex-snapshot
FGF and Shh Signals Control Dopaminergic and Serotonergic Cell Fate in the Anterior Neural Plate
inferredcites →https://doi.org/10.1016/s0092-8674(00)81705-5openalex-snapshot
Randomization of Left–Right Asymmetry due to Loss of Nodal Cilia Generating Leftward Flow of Extraembryonic Fluid in Mice Lacking KIF3B Motor Protein
inferredcites →https://doi.org/10.1016/s0092-8674(01)00385-3openalex-snapshot
Smoothened Mutants Reveal Redundant Roles for Shh and Ihh Signaling Including Regulation of L/R Asymmetry by the Mouse Node
inferredcites →https://doi.org/10.1016/s0092-8674(01)00437-8openalex-snapshot
FGF Signaling Controls Somite Boundary Position and Regulates Segmentation Clock Control of Spatiotemporal Hox Gene Activation
inferredcites →https://doi.org/10.1016/s0092-8674(03)00511-7openalex-snapshot
Two Populations of Node Monocilia Initiate Left-Right Asymmetry in the Mouse
inferredcites →https://doi.org/10.1016/s1097-2765(00)80197-5openalex-snapshot
Abnormal Nodal Flow Precedes Situs Inversus in iv and inv mice
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FGF Is an Essential Mitogen and Chemoattractant for the Air Sacs of the Drosophila Tracheal System
inferredcites →https://doi.org/10.1034/j.1600-0854.2000.010105.xopenalex-snapshot
Stirring up Development with the Heterotrimeric Kinesin KIF3
inferredcites →https://doi.org/10.1038/35079648openalex-snapshot
A freely diffusible form of Sonic hedgehog mediates long-range signalling
inferredcites →https://doi.org/10.1038/nature00849openalex-snapshot
Determination of left–right patterning of the mouse embryo by artificial nodal flow
inferredcites →https://doi.org/10.1038/nature02061openalex-snapshot
Hedgehog signalling in the mouse requires intraflagellar transport proteins
inferredcites →https://doi.org/10.1038/nature02190openalex-snapshot
Notch activity acts as a sensor for extracellular calcium during vertebrate left–right determination
inferredcites →https://doi.org/10.1038/nature02216openalex-snapshot
fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo
inferredcites →https://doi.org/10.1046/j.1440-1711.2002.01098.xopenalex-snapshot
Costimulation of T cell receptor‐triggered IL‐2 production by Jurkat T cells via fibroblast growth factor receptor 1 upon its engagement by CD56
inferredcites →https://doi.org/10.1073/pnas.96.20.11376openalex-snapshot
Multiple left-right asymmetry defects in Shh −/− mutant mice unveil a convergence of the Shh and retinoic acid pathways in the control of Lefty-1
inferredcites →https://doi.org/10.1083/jcb.125.5.1095openalex-snapshot
KIF3A is a new microtubule-based anterograde motor in the nerve axon.
inferredcites →https://doi.org/10.1083/jcb.145.4.825openalex-snapshot
Left-Right Asymmetry and Kinesin Superfamily Protein KIF3A: New Insights in Determination of Laterality and Mesoderm Induction by kif3A−/− Mice Analysis
inferredcites →https://doi.org/10.1101/gad.1053803openalex-snapshot
A two-cilia model for vertebrate left-right axis specification: Figure 1.
inferredcites →https://doi.org/10.1111/j.1447-073x.2004.00072.xopenalex-snapshot
Motor or sensor: A new aspect of primary cilia function
inferredcites →https://doi.org/10.1126/science.1096966openalex-snapshot
The Limb Bud Shh-Fgf Feedback Loop Is Terminated by Expansion of Former ZPA Cells
inferredcites →https://doi.org/10.1126/science.276.5314.955openalex-snapshot
Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with Inhibitors
inferredcites →https://doi.org/10.1126/science.285.5426.403openalex-snapshot
Differences in Left-Right Axis Pathways in Mouse and Chick: Functions of FGF8 and SHH
inferredcites →https://doi.org/10.1146/annurev.cellbio.19.111401.091318openalex-snapshot
Intraflagellar Transport
inferredcites →https://doi.org/10.1172/jci200420384openalex-snapshot
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate
inferredcites →https://doi.org/10.1242/dev.00178openalex-snapshot
Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling
inferredcites →https://doi.org/10.1242/dev.00964openalex-snapshot
Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations
inferredcites →https://doi.org/10.1242/dev.01027openalex-snapshot
Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Mammalian Embryo: Establishment of the Embryonic Axes
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Breaking the left-right axis: do nodal parcels pass a signal to the left?
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Greased hedgehogs: New links between hedgehog signaling and cholesterol metabolism
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Heart defects in X‐linked heterotaxy: Evidence for a genetic interaction of Zic3 with the nodal signaling pathway
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A mutation in the zebrafish Na,K‐ATPase subunit atp1a1a.1 provides genetic evidence that the sodium potassium pump contributes to left‐right asymmetry downstream or in parallel to nodal flow
inferred← citeshttps://doi.org/10.1002/dvdy.20879openalex-snapshot
Role for retinoid signaling in left–right asymmetric digestive organ morphogenesis
inferred← citeshttps://doi.org/10.1002/dvdy.20992openalex-snapshot
Mice with mutations in Mahogunin ring finger‐1 (Mgrn1) exhibit abnormal patterning of the left–right axis
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Analysis of Kupffer's vesicle in zebrafish embryos using a cave automated virtual environment
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Primary cilia sensitize endothelial cells for fluid shear stress
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Gap junctions relay FGF8‐mediated right‐sided repression of Nodal in rabbit
inferred← citeshttps://doi.org/10.1002/dvdy.21598openalex-snapshot
Morphogenesis of the node and notochord: The cellular basis for the establishment and maintenance of left–right asymmetry in the mouse
inferred← citeshttps://doi.org/10.1002/dvdy.21672openalex-snapshot
Fluid dynamics of nodal flow and left–right patterning in development
inferred← citeshttps://doi.org/10.1002/dvdy.21704openalex-snapshot
Calcium signaling: A common thread in vertebrate left–right axis development
inferred← citeshttps://doi.org/10.1002/dvdy.21730openalex-snapshot
Fluid dynamics in zebrafish Kupffer's vesicle
inferred← citeshttps://doi.org/10.1002/dvdy.21855openalex-snapshot
Xenopus , an ideal model system to study vertebrate left‐right asymmetry
inferred← citeshttps://doi.org/10.1002/dvdy.21874openalex-snapshot
Mouse mutagenesis identifies novel roles for left–right patterning genes in pulmonary, craniofacial, ocular, and limb development
inferred← citeshttps://doi.org/10.1002/dvdy.22282openalex-snapshot
Dissecting the role of Fgf signaling during gastrulation and left‐right axis formation in mouse embryos using chemical inhibitors
inferred← citeshttps://doi.org/10.1002/dvdy.22756openalex-snapshot
Axonemal positioning and orientation in three‐dimensional space for primary cilia: What is known, what is assumed, and what needs clarification
inferred← citeshttps://doi.org/10.1002/dvg.20444openalex-snapshot
Retinoic acid signaling in development: Tissue‐specific functions and evolutionary origins
inferred← citeshttps://doi.org/10.1002/dvg.20825openalex-snapshot
Polarity proteins are required for left–right axis orientation and twin–twin instruction
inferred← citeshttps://doi.org/10.1002/dvg.22752openalex-snapshot
Left–right asymmetry in the sea urchin
inferred← citeshttps://doi.org/10.1002/dvg.22774openalex-snapshot
Are there conserved roles for the extracellular matrix, cilia, and junctional complexes in left‐right patterning?
inferred← citeshttps://doi.org/10.1002/dvg.22783openalex-snapshot
Follow your gut: Relaying information from the site of left–right symmetry breaking in the mouse
inferred← citeshttps://doi.org/10.1002/jev2.12151openalex-snapshot
In sickness and in health: The functional role of extracellular vesicles in physiology and pathology in vivo
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Unconventional Secretion of Angiogenic Sonic Hedgehog–Containing Extra‐Large Extracellular Vesicles is Driven by PI3K–Rab18‐GDP Signalling
inferred← citeshttps://doi.org/10.1002/jor.23732openalex-snapshot
The primary cilium as a signaling nexus for growth plate function and subsequent skeletal development
inferred← citeshttps://doi.org/10.1002/jsp2.1030openalex-snapshot
Latest advances in intervertebral disc development and progenitor cells
inferred← citeshttps://doi.org/10.1002/mrd.23650openalex-snapshot
Structures and functions of cilia during vertebrate embryo development
inferred← citeshttps://doi.org/10.1002/path.4843openalex-snapshot
Motile and non‐motile cilia in human pathology: from function to phenotypes
inferred← citeshttps://doi.org/10.1002/wdev.2openalex-snapshot
Morphogen gradients in development: from form to function
inferred← citeshttps://doi.org/10.1007/3-540-49522-3_5openalex-snapshot
Intracellular Transport and Kinesin Superfamily Proteins: Structure, Function and Dynamics
inferred← citeshttps://doi.org/10.1007/978-0-387-73050-9_8openalex-snapshot
Collective Effects in Arrays of Cilia and Rotational Motors
inferred← citeshttps://doi.org/10.1007/978-1-4419-8435-7_2openalex-snapshot
Regulation of the Hedgehog Morphogene Gradient
inferred← citeshttps://doi.org/10.1007/978-3-030-12457-1_21openalex-snapshot
Widespread Roles of CaMK-II in Developmental Pathways
inferred← citeshttps://doi.org/10.1007/978-3-031-44087-8_43openalex-snapshot
Molecular Pathways and Animal Models of Defects in Situs
inferred← citeshttps://doi.org/10.1007/978-3-031-44087-8_9openalex-snapshot
Establishment of Cardiac Laterality
inferred← citeshttps://doi.org/10.1007/978-3-319-69620-1_13openalex-snapshot
Pulmonary Complications of Heterotaxy Syndromes
inferred← citeshttps://doi.org/10.1007/978-3-319-99328-7_4openalex-snapshot
Exosomes for Regeneration, Rejuvenation, and Repair
inferred← citeshttps://doi.org/10.1007/978-3-7091-1883-2_39openalex-snapshot
Molecular Pathways and Animal Models of Defects of Situs
inferred← citeshttps://doi.org/10.1007/978-3-7091-1883-2_7openalex-snapshot
Establishment of Cardiac Laterality
inferred← citeshttps://doi.org/10.1007/978-4-431-54628-3openalex-snapshot
Etiology and Morphogenesis of Congenital Heart Disease
inferred← citeshttps://doi.org/10.1007/978-4-431-54628-3_6openalex-snapshot
Left-Right Asymmetry and Human Heterotaxy Syndrome
inferred← citeshttps://doi.org/10.1007/978-4-431-56609-0_30openalex-snapshot
Left–Right Specification in the Embryonic and Larval Development of Amphibians
inferred← citeshttps://doi.org/10.1007/978-90-481-8622-8_14openalex-snapshot
Prominin-1: A Distinct Cholesterol-Binding Membrane Protein and the Organisation of the Apical Plasma Membrane of Epithelial Cells
inferred← citeshttps://doi.org/10.1007/978-90-481-9881-8_14openalex-snapshot
Primary Cilia are Mechanosensory Organelles in Vestibular Tissues
inferred← citeshttps://doi.org/10.1007/s00018-005-5503-7openalex-snapshot
Nodal signals pattern vertebrate embryos
inferred← citeshttps://doi.org/10.1007/s00018-011-0695-5openalex-snapshot
The multiple roles of Notch signaling during left-right patterning
inferred← citeshttps://doi.org/10.1007/s00018-013-1399-9openalex-snapshot
Establishment of left–right asymmetry in vertebrate development: the node in mouse embryos
inferred← citeshttps://doi.org/10.1007/s00018-013-1430-1openalex-snapshot
Of mice and men: molecular genetics of congenital heart disease
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Control of signaling molecule range during developmental patterning
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Laterality in modern medicine: a historical overview of animal laterality, human laterality, and current influences in clinical practice
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Transcriptional Control of Left–Right Patterning in Cardiac Development
inferred← citeshttps://doi.org/10.1007/s00418-007-0334-2openalex-snapshot
Differential expression of Prominin-1 (CD133) and Prominin-2 in major cephalic exocrine glands of adult mice
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Structure and function of mammalian cilia
inferred← citeshttps://doi.org/10.1007/s00424-006-0168-0openalex-snapshot
Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1)
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Ion flow regulates left–right asymmetry in sea urchin development
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Neurovesicles in Brain Development
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Ciliary Extracellular Vesicles: Txt Msg Organelles
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Mathematical embryology: the fluid mechanics of nodal cilia
inferred← citeshttps://doi.org/10.1007/s10735-005-9000-yopenalex-snapshot
Do we know anything about how left–right asymmetry is first established in the vertebrate embryo?
inferred← citeshttps://doi.org/10.1007/s10815-015-0617-9openalex-snapshot
Association of polymorphisms in tektin-t gene with idiopathic asthenozoospermia in Sichuan, China
inferred← citeshttps://doi.org/10.1007/s11936-025-01114-1openalex-snapshot
The Role of Left-Right Asymmetry in Congenital Heart Defects: Taking the Right Turn
inferred← citeshttps://doi.org/10.1007/s12035-019-01646-1openalex-snapshot
Structural Asymmetry in the Frontal and Temporal Lobes Is Associated with PCSK6 VNTR Polymorphism
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The mini player with diverse functions: extracellular vesicles in cell biology, disease, and therapeutics
inferred← citeshttps://doi.org/10.1016/b978-0-12-374145-5.00230-8openalex-snapshot
Regulation of Vertebrate Left-Right Axis Development by Calcium
inferred← citeshttps://doi.org/10.1016/b978-0-12-381280-3.00004-xopenalex-snapshot
The Gastric Mucosa
inferred← citeshttps://doi.org/10.1016/b978-0-12-381332-9.00011-6openalex-snapshot
Retinoids and Heart Development
inferred← citeshttps://doi.org/10.1016/b978-0-12-381332-9.00013-xopenalex-snapshot
Cardiac Left–Right Asymmetry
inferred← citeshttps://doi.org/10.1016/b978-0-12-381462-3.00080-xopenalex-snapshot
Autosomal Dominant Polycystic Kidney Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-382004-4.10024-xopenalex-snapshot
Dynein Dysfunction as a Cause of Primary Ciliary Dyskinesia and Other Ciliopathies
inferred← citeshttps://doi.org/10.1016/b978-0-12-382008-2.00006-4openalex-snapshot
Early Mouse Development
inferred← citeshttps://doi.org/10.1016/b978-0-12-394447-4.20060-6openalex-snapshot
Kinesin Superfamily Proteins (KIFs) as a Fundamental Component of Life: Intracellular Transport and Beyond
inferred← citeshttps://doi.org/10.1016/b978-0-12-397944-5.00008-0openalex-snapshot
Visualization of Mouse Nodal Cilia and Nodal Flow
inferred← citeshttps://doi.org/10.1016/b978-0-12-405206-2.00001-6openalex-snapshot
Molecular Basis of Cardiac Development
inferred← citeshttps://doi.org/10.1016/b978-0-12-407696-9.00007-5openalex-snapshot
Calcium Signaling in Extraembryonic Domains During Early Teleost Development
inferred← citeshttps://doi.org/10.1016/b978-0-12-408077-5.00007-9openalex-snapshot
A Critical Review of Experimental and Modeling Research on the Leftward Flow Leading to Left-Right Symmetry Breaking in the Embryonic Node
inferred← citeshttps://doi.org/10.1016/b978-0-12-449851-8.00024-3openalex-snapshot
Polycystic Kidney Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-809470-9.00014-xopenalex-snapshot
Dynein dysfunction as a cause of primary ciliary dyskinesia and other ciliopathies
inferred← citeshttps://doi.org/10.1016/b978-0-12-815389-5.00021-6openalex-snapshot
Renal cilia structure, function, and physiology
inferred← citeshttps://doi.org/10.1016/b978-0-12-819460-7.00301-7openalex-snapshot
Further Reading | Kinesin Superfamily Proteins
inferred← citeshttps://doi.org/10.1016/b978-0-12-821618-7.00177-2openalex-snapshot
The Expanding Universe of Kinesin Superfamily Molecular Motors (KIFs) – The Postmen Who Govern the Country
inferred← citeshttps://doi.org/10.1016/b978-0-323-35214-7.00149-9openalex-snapshot
Genetics of Sex Determination and Differentiation
inferred← citeshttps://doi.org/10.1016/b978-0-443-06811-9.10003-xopenalex-snapshot
Third Week: Becoming Trilaminar and Establishing Body Axes
inferred← citeshttps://doi.org/10.1016/b978-012088488-9.50084-xopenalex-snapshot
Autosomal Dominant Polycystic Kidney Disease and Inherited Cystic Diseases
inferred← citeshttps://doi.org/10.1016/b978-032304048-8.50071-2openalex-snapshot
Respiratory Ciliary Dysfunction
inferred← citeshttps://doi.org/10.1016/b978-1-4160-3479-7.10183-1openalex-snapshot
Genetics of Sex Determination and Differentiation
inferred← citeshttps://doi.org/10.1016/bs.mcb.2014.12.010openalex-snapshot
Quantitative description of fluid flows produced by left–right cilia in zebrafish
inferred← citeshttps://doi.org/10.1016/j.abb.2018.08.009openalex-snapshot
The release of glycosylphosphatidylinositol-anchored proteins from the cell surface
inferred← citeshttps://doi.org/10.1016/j.ajhg.2018.10.020openalex-snapshot
Recessive DNAH9 Loss-of-Function Mutations Cause Laterality Defects and Subtle Respiratory Ciliary-Beating Defects
inferred← citeshttps://doi.org/10.1016/j.bbadis.2007.01.003openalex-snapshot
TRPP2 and autosomal dominant polycystic kidney disease
inferred← citeshttps://doi.org/10.1016/j.bbagen.2011.05.003openalex-snapshot
A method to assess the migration properties of cell-derived microparticles within a living tissue
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2019.02.016openalex-snapshot
An element for development: Calcium signaling in mammalian reproduction and development
inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.10.103openalex-snapshot
Kidney injury molecule 1 (Kim1) is a novel ciliary molecule and interactor of polycystin 2
inferred← citeshttps://doi.org/10.1016/j.biosystems.2018.10.001openalex-snapshot
Increasing complexity: Mechanical guidance and feedback loops as a basis for self-organization in morphogenesis
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2007.10.010openalex-snapshot
The particles of the embryonic cerebrospinal fluid: How could they influence brain development?
inferred← citeshttps://doi.org/10.1016/j.cdev.2024.203944openalex-snapshot
‘Three signals - three body axes’ as patterning principle in bilaterians
inferred← citeshttps://doi.org/10.1016/j.ceb.2006.12.006openalex-snapshot
Left–right asymmetry: class I myosins show the direction
inferred← citeshttps://doi.org/10.1016/j.ceb.2007.02.005openalex-snapshot
Shifting paradigms in Hedgehog signaling
inferred← citeshttps://doi.org/10.1016/j.ceb.2009.10.010openalex-snapshot
Intraflagellar transport: it's not just for cilia anymore
inferred← citeshttps://doi.org/10.1016/j.ceb.2011.12.007openalex-snapshot
Cilia functions in development
inferred← citeshttps://doi.org/10.1016/j.ceb.2012.01.002openalex-snapshot
Cilia, KIF3 molecular motor and nodal flow
inferred← citeshttps://doi.org/10.1016/j.ceb.2012.02.001openalex-snapshot
Release and transportation of Hedgehog molecules
inferred← citeshttps://doi.org/10.1016/j.ceb.2025.102564openalex-snapshot
Mechanisms of left–right symmetry breaking across scales
inferred← citeshttps://doi.org/10.1016/j.ceca.2006.03.006openalex-snapshot
Quantitative two-photon Ca2+ imaging via fluorescence lifetime analysis
inferred← citeshttps://doi.org/10.1016/j.cell.2006.02.044openalex-snapshot
Intraflagellar Transport Particles Participate Directly in Cilium-Generated Signaling in Chlamydomonas
inferred← citeshttps://doi.org/10.1016/j.cell.2006.03.002openalex-snapshot
Nodal Flow and the Generation of Left-Right Asymmetry
inferred← citeshttps://doi.org/10.1016/j.cell.2007.04.035openalex-snapshot
HEF1-Dependent Aurora A Activation Induces Disassembly of the Primary Cilium
inferred← citeshttps://doi.org/10.1016/j.cell.2011.05.030openalex-snapshot
A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development
inferred← citeshttps://doi.org/10.1016/j.cell.2013.05.008openalex-snapshot
Forces in Tissue Morphogenesis and Patterning
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.06.100openalex-snapshot
The ESCRT-III Protein CHMP1A Mediates Secretion of Sonic Hedgehog on a Distinctive Subtype of Extracellular Vesicles
inferred← citeshttps://doi.org/10.1016/j.cub.2006.07.012openalex-snapshot
Cilia: Tuning in to the Cell's Antenna
inferred← citeshttps://doi.org/10.1016/j.cub.2009.05.025openalex-snapshot
The Primary Cilium as a Complex Signaling Center
inferred← citeshttps://doi.org/10.1016/j.cub.2009.09.057openalex-snapshot
An Hh-Dependent Pathway in Lateral Plate Mesoderm Enables the Generation of Left/Right Asymmetry
inferred← citeshttps://doi.org/10.1016/j.cub.2010.02.061openalex-snapshot
The Nodal Inhibitor Coco Is a Critical Target of Leftward Flow in Xenopus
inferred← citeshttps://doi.org/10.1016/j.cub.2011.10.040openalex-snapshot
The P4-ATPase TAT-5 Inhibits the Budding of Extracellular Vesicles in C. elegans Embryos
inferred← citeshttps://doi.org/10.1016/j.cub.2014.12.051openalex-snapshot
Intraciliary Calcium Oscillations Initiate Vertebrate Left-Right Asymmetry
inferred← citeshttps://doi.org/10.1016/j.cub.2015.10.057openalex-snapshot
Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis
inferred← citeshttps://doi.org/10.1016/j.cub.2017.07.010openalex-snapshot
Coordination of Morphogenesis and Cell-Fate Specification in Development
inferred← citeshttps://doi.org/10.1016/j.devcel.2005.12.006openalex-snapshot
Mechanisms of Mechanotransduction
inferred← citeshttps://doi.org/10.1016/j.devcel.2006.06.009openalex-snapshot
The Emerging Complexity of the Vertebrate Cilium: New Functional Roles for an Ancient Organelle
inferred← citeshttps://doi.org/10.1016/j.devcel.2009.04.004openalex-snapshot
Fibroblast “Cilia Growth” Factor in the Development of Left-Right Asymmetry
inferred← citeshttps://doi.org/10.1016/j.devcel.2012.07.016openalex-snapshot
Planar Polarized Protrusions Break the Symmetry of EGFR Signaling during Drosophila Bract Cell Fate Induction
inferred← citeshttps://doi.org/10.1016/j.devcel.2014.04.030openalex-snapshot
Left-Right Organizer Flow Dynamics: How Much Cilia Activity Reliably Yields Laterality?
inferred← citeshttps://doi.org/10.1016/j.devcel.2014.12.004openalex-snapshot
Endocytosis of Hedgehog through Dispatched Regulates Long-Range Signaling
inferred← citeshttps://doi.org/10.1016/j.devcel.2015.10.001openalex-snapshot
Absence of Radial Spokes in Mouse Node Cilia Is Required for Rotational Movement but Confers Ultrastructural Instability as a Trade-Off
inferred← citeshttps://doi.org/10.1016/j.devcel.2018.10.027openalex-snapshot
A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice
inferred← citeshttps://doi.org/10.1016/j.devcel.2022.09.007openalex-snapshot
KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice
inferred← citeshttps://doi.org/10.1016/j.devcel.2023.06.002openalex-snapshot
Nodal flow transfers polycystin to determine mouse left-right asymmetry
inferred← citeshttps://doi.org/10.1016/j.devcel.2023.07.016openalex-snapshot
Traveling to the left: A story of PKD1L1-containing vesicles
inferred← citeshttps://doi.org/10.1016/j.ejmg.2005.12.003openalex-snapshot
Human laterality disorders
inferred← citeshttps://doi.org/10.1016/j.ejmg.2022.104496openalex-snapshot
Expanding the phenotype of males with OFD1 pathogenic variants-a case report and literature review
inferred← citeshttps://doi.org/10.1016/j.gde.2005.12.006openalex-snapshot
Release and trafficking of lipid-linked morphogens
inferred← citeshttps://doi.org/10.1016/j.gde.2007.05.008openalex-snapshot
Strategies to establish left/right asymmetry in vertebrates and invertebrates
inferred← citeshttps://doi.org/10.1016/j.gde.2009.04.006openalex-snapshot
Lipid-modified morphogens: functions of fats
inferred← citeshttps://doi.org/10.1016/j.gde.2013.04.011openalex-snapshot
Hedgehog on the move: a precise spatial control of Hedgehog dispersion shapes the gradient
inferred← citeshttps://doi.org/10.1016/j.gep.2018.08.004openalex-snapshot
Analysis of the FGFR spatiotemporal expression pattern within the chicken scleral ossicle system
inferred← citeshttps://doi.org/10.1016/j.jbiomech.2008.10.040openalex-snapshot
The active and passive ciliary motion in the embryo node: A computational fluid dynamics model
inferred← citeshttps://doi.org/10.1016/j.jri.2016.08.007openalex-snapshot
Association of polymorphisms in PATE1 gene with idiopathic asthenozoospermia in Sichuan, China
inferred← citeshttps://doi.org/10.1016/j.jsb.2006.11.004openalex-snapshot
Analysis of the orientation of primary cilia in growth plate cartilage: A mathematical method based on multiphoton microscopical images
inferred← citeshttps://doi.org/10.1016/j.jtbi.2018.10.015openalex-snapshot
Wall stress enhanced exocytosis of extracellular vesicles as a possible mechanism of left-right symmetry-breaking in vertebrate development
inferred← citeshttps://doi.org/10.1016/j.krcp.2014.05.002openalex-snapshot
Cyst growth, polycystins, and primary cilia in autosomal dominant polycystic kidney disease
inferred← citeshttps://doi.org/10.1016/j.medengphy.2010.10.020openalex-snapshot
Ciliary behaviour and mechano-transduction in the embryonic node: Computational testing of hypotheses
inferred← citeshttps://doi.org/10.1016/j.mod.2008.02.004openalex-snapshot
Suppression of the endoplasmic reticulum calcium pump during zebrafish gastrulation affects left–right asymmetry of the heart and brain
inferred← citeshttps://doi.org/10.1016/j.mod.2012.05.005openalex-snapshot
How insights from cardiovascular developmental biology have impacted the care of infants and children with congenital heart disease
inferred← citeshttps://doi.org/10.1016/j.nbd.2017.12.016openalex-snapshot
Retinoic acid synthesis by NG2 expressing cells promotes a permissive environment for axonal outgrowth
inferred← citeshttps://doi.org/10.1016/j.neuron.2010.09.039openalex-snapshot
Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease
inferred← citeshttps://doi.org/10.1016/j.neuron.2016.05.002openalex-snapshot
The Molecular Motor KIF1A Transports the TrkA Neurotrophin Receptor and Is Essential for Sensory Neuron Survival and Function
inferred← citeshttps://doi.org/10.1016/j.newton.2026.100672openalex-snapshot
Viscosity-mediated signal amplification enables robust left-right symmetry breaking in the mouse node
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2012.08.004openalex-snapshot
Prevailing importance of the hedgehog signaling pathway and the potential for treatment advancement in sarcoma
inferred← citeshttps://doi.org/10.1016/j.physrep.2024.05.002openalex-snapshot
Waves, patterns, bifurcations: A tutorial review on the vertebrate segmentation clock
inferred← citeshttps://doi.org/10.1016/j.reprotox.2014.05.005openalex-snapshot
Cilia and ciliopathies: Classic examples linking phenotype and genotype—An overview
inferred← citeshttps://doi.org/10.1016/j.semcancer.2021.04.003openalex-snapshot
Hedgehog signaling mechanism and role in cancer
inferred← citeshttps://doi.org/10.1016/j.semcdb.2008.11.009openalex-snapshot
Balancing segmentation and laterality during vertebrate development
inferred← citeshttps://doi.org/10.1016/j.semcdb.2008.11.010openalex-snapshot
Perspectives and open problems in the early phases of left–right patterning
inferred← citeshttps://doi.org/10.1016/j.semcdb.2014.06.016openalex-snapshot
Hedgehog and its circuitous journey from producing to target cells
inferred← citeshttps://doi.org/10.1016/j.semcdb.2014.09.013openalex-snapshot
The role of the protein tyrosine phosphatase SHP2 in cardiac development and disease
inferred← citeshttps://doi.org/10.1016/j.semcdb.2020.03.007openalex-snapshot
Cilia and centrosomes: Ultrastructural and mechanical perspectives
inferred← citeshttps://doi.org/10.1016/j.semcdb.2020.06.003openalex-snapshot
Right, left and cilia: How asymmetry is established
inferred← citeshttps://doi.org/10.1016/j.tcb.2017.10.003openalex-snapshot
Wnt and Hedgehog: Secretion of Lipid-Modified Morphogens
inferred← citeshttps://doi.org/10.1016/j.tcm.2006.04.002openalex-snapshot
Hedgehog Turns Lipoproteins Into Janus-Faced Particles
inferred← citeshttps://doi.org/10.1016/j.tig.2017.06.004openalex-snapshot
Left–Right Patterning: Breaking Symmetry to Asymmetric Morphogenesis
inferred← citeshttps://doi.org/10.1016/j.vesic.2024.100048openalex-snapshot
An extracellular vesicle based hypothesis for the genesis of the polycystic kidney diseases
inferred← citeshttps://doi.org/10.1016/j.ydbio.2005.07.038openalex-snapshot
Left–right asymmetry and congenital cardiac defects: Getting to the heart of the matter in vertebrate left–right axis determination
inferred← citeshttps://doi.org/10.1016/j.ydbio.2005.12.018openalex-snapshot
Retinoic acid signaling is essential for formation of the heart tube in Xenopus
inferred← citeshttps://doi.org/10.1016/j.ydbio.2006.09.001openalex-snapshot
Hippi is essential for node cilia assembly and Sonic hedgehog signaling
inferred← citeshttps://doi.org/10.1016/j.ydbio.2006.11.020openalex-snapshot
The roles of Groucho/Tle in left–right asymmetry and Kupffer’s vesicle organogenesis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2008.10.020openalex-snapshot
Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4
inferred← citeshttps://doi.org/10.1016/j.ydbio.2009.04.011openalex-snapshot
Shaping the zebrafish heart: From left–right axis specification to epithelial tissue morphogenesis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2009.05.547openalex-snapshot
Flow on the right side of the gastrocoel roof plate is dispensable for symmetry breakage in the frog Xenopus laevis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2010.03.011openalex-snapshot
Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.12.030openalex-snapshot
RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow
inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.04.011openalex-snapshot
Defective Nodal and Cerl2 expression in the Arl13bhnn mutant node underlie its heterotaxia
inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.11.022openalex-snapshot
ENC1-like integrates the retinoic acid/FGF signaling pathways to modulate ciliogenesis of Kupffer’s vesicle during zebrafish embryonic development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2013.01.018openalex-snapshot
Asymmetric distribution of dynamic calcium signals in the node of mouse embryo during left–right axis formation
inferred← citeshttps://doi.org/10.1016/j.ydbio.2013.03.021openalex-snapshot
A unified model for left–right asymmetry? Comparison and synthesis of molecular models of embryonic laterality
inferred← citeshttps://doi.org/10.1016/j.ydbio.2013.05.011openalex-snapshot
Wnt signaling regulates left–right axis formation in the node of mouse embryos
inferred← citeshttps://doi.org/10.1016/j.ydbio.2015.08.002openalex-snapshot
The V-ATPase accessory protein Atp6ap1b mediates dorsal forerunner cell proliferation and left–right asymmetry in zebrafish
inferred← citeshttps://doi.org/10.1016/j.ydbio.2016.02.008openalex-snapshot
Contribution of hedgehog signaling to the establishment of left–right asymmetry in the sea urchin
inferred← citeshttps://doi.org/10.1016/j.ydbio.2016.05.030openalex-snapshot
Enteric nervous system assembly: Functional integration within the developing gut
inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.04.015openalex-snapshot
From good to bad: Intravital imaging of the hijack of physiological processes by cancer cells
inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.05.010openalex-snapshot
Modelling asymmetric somitogenesis: Deciphering the mechanisms behind species differences
inferred← citeshttps://doi.org/10.1016/j.ydbio.2021.10.005openalex-snapshot
Corpuscles of Stannius development requires FGF signaling
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