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Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/art.23992openalex-snapshot
Treatment of rheumatoid arthritis with a syk kinase inhibitor: A twelve‐week, randomized, placebo‐controlled trial
inferredcites →https://doi.org/10.1016/0092-8674(95)90490-5openalex-snapshot
Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock
inferredcites →https://doi.org/10.1016/j.chom.2008.08.007openalex-snapshot
The Caspase-1 Inflammasome: A Pilot of Innate Immune Responses
inferredcites →https://doi.org/10.1016/j.clim.2007.03.543openalex-snapshot
Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor
inferredcites →https://doi.org/10.1016/j.immuni.2008.09.013openalex-snapshot
Receptor-Independent, Direct Membrane Binding Leads to Cell-Surface Lipid Sorting and Syk Kinase Activation in Dendritic Cells
inferredcites →https://doi.org/10.1016/s1074-7613(00)80086-2openalex-snapshot
Unresponsiveness of MyD88-Deficient Mice to Endotoxin
inferredcites →https://doi.org/10.1038/nature02664openalex-snapshot
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
inferredcites →https://doi.org/10.1038/nature04515openalex-snapshot
Cryopyrin activates the inflammasome in response to toxins and ATP
inferredcites →https://doi.org/10.1038/nature04516openalex-snapshot
Gout-associated uric acid crystals activate the NALP3 inflammasome
inferredcites →https://doi.org/10.1038/nature04926openalex-snapshot
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
inferredcites →https://doi.org/10.1038/nature06664openalex-snapshot
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
inferredcites →https://doi.org/10.1038/nature07013openalex-snapshot
CLEC5A is critical for dengue-virus-induced lethal disease
inferredcites →https://doi.org/10.1038/ng1724openalex-snapshot
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
inferredcites →https://doi.org/10.1038/ni.1631openalex-snapshot
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
inferredcites →https://doi.org/10.1038/ni.1636openalex-snapshot
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
inferredcites →https://doi.org/10.1038/ni.1651openalex-snapshot
Mincle is an ITAM-coupled activating receptor that senses damaged cells
inferredcites →https://doi.org/10.1038/ni1417openalex-snapshot
Myeloid C-type lectins in innate immunity
inferredcites →https://doi.org/10.1038/ni1460openalex-snapshot
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
inferredcites →https://doi.org/10.1038/ni1466openalex-snapshot
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors
inferredcites →https://doi.org/10.1038/nri1257-c1openalex-snapshot
Extrathymic T-cell differentiation in vitro
inferredcites →https://doi.org/10.1038/onc.2008.59openalex-snapshot
Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice
inferredcites →https://doi.org/10.1038/sj.cdd.4402195openalex-snapshot
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
inferredcites →https://doi.org/10.1074/jbc.m608083200openalex-snapshot
ATP Activates a Reactive Oxygen Species-dependent Oxidative Stress Response and Secretion of Proinflammatory Cytokines in Macrophages
inferredcites →https://doi.org/10.1086/503363openalex-snapshot
Endogenous Interleukin (IL)–1α and IL‐1β Are Crucial for Host Defense against Disseminated Candidiasis
inferredcites →https://doi.org/10.1093/glycob/cwn046openalex-snapshot
Human and mouse macrophage-inducible C-type lectin (Mincle) bind Candida albicans
inferredcites →https://doi.org/10.1124/jpet.106.109058openalex-snapshot
R406, an Orally Available Spleen Tyrosine Kinase Inhibitor Blocks Fc Receptor Signaling and Reduces Immune Complex-Mediated Inflammation
inferredcites →https://doi.org/10.1126/science.1156995openalex-snapshot
Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica
inferredcites →https://doi.org/10.1128/iai.68.9.5126-5131.2000openalex-snapshot
Interleukin 18 Restores Defective Th1 Immunity toCandida albicansin Caspase 1-Deficient Mice
inferredcites →https://doi.org/10.1182/blood-2005-03-1239openalex-snapshot
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1186/s13071-024-06593-yzenodo-depositor-declared
FcRγIIA attenuates pathology of cutaneous leishmaniasis and modulates ITAMa/i balance
inferred← citeshttps://doi.org/10.2139/ssrn.3904659openalex-extracted
Nortriptyline Induces Sterile Inflammation by Directly Targeting NLRP3 Inflammasome Activation
inferred← citeshttps://doi.org/10.1002/9780470015902.a0020175.pub2openalex-snapshot
Pattern Recognition Receptors
inferred← citeshttps://doi.org/10.1002/9781118826621.ch8openalex-snapshot
Inflammasomes and Inflammation
inferred← citeshttps://doi.org/10.1002/art.27438openalex-snapshot
Genetic deficiency of Syk protects mice from autoantibody‐induced arthritis
inferred← citeshttps://doi.org/10.1002/chem.201802577openalex-snapshot
On‐Chip Screening of a Glycomimetic Library with C‐Type Lectins Reveals Structural Features Responsible for Preferential Binding of Dectin‐2 over DC‐SIGN/R and Langerin
inferred← citeshttps://doi.org/10.1002/cti2.1247openalex-snapshot
The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders
inferred← citeshttps://doi.org/10.1002/ctm2.1449openalex-snapshot
Dracorhodin targeting CMPK2 attenuates inflammation: A novel approach to sepsis therapy
inferred← citeshttps://doi.org/10.1002/eji.200940168openalex-snapshot
Signaling by ROS drives inflammasome activation
inferred← citeshttps://doi.org/10.1002/eji.200940172openalex-snapshot
The role of inflammasomes in the immunostimulatory effects of particulate vaccine adjuvants
inferred← citeshttps://doi.org/10.1002/eji.200940180openalex-snapshot
Inflammasomes as microbial sensors
inferred← citeshttps://doi.org/10.1002/eji.201040490openalex-snapshot
Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase‐1 activation in macrophages
inferred← citeshttps://doi.org/10.1002/eji.201041226openalex-snapshot
The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis
inferred← citeshttps://doi.org/10.1002/eji.201141490openalex-snapshot
Recognition of yeast nucleic acids triggers a host‐protective type I interferon response
inferred← citeshttps://doi.org/10.1002/eji.201141548openalex-snapshot
Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis
inferred← citeshttps://doi.org/10.1002/eji.201242691openalex-snapshot
Secreted aspartic proteases of C andida albicans activate the NLRP 3 inflammasome
inferred← citeshttps://doi.org/10.1002/eji.201444707openalex-snapshot
Impaired NLRP3 inflammasome activity during fetal development regulates IL‐1β production in human monocytes
inferred← citeshttps://doi.org/10.1002/eji.201444744openalex-snapshot
Rapid CD4+ T‐cell responses to bacterial flagellin require dendritic cell expression of Syk and CARD9
inferred← citeshttps://doi.org/10.1002/eji.201545537openalex-snapshot
TSLP production by dendritic cells is modulated by IL‐1β and components of the endoplasmic reticulum stress response
inferred← citeshttps://doi.org/10.1002/eji.201646765openalex-snapshot
Card9‐dependent IL‐1β regulates IL‐22 production from group 3 innate lymphoid cells and promotes colitis‐associated cancer
inferred← citeshttps://doi.org/10.1002/eji.201646775openalex-snapshot
Card9 controls Dectin‐1‐induced T‐cell cytotoxicity and tumor growth in mice
inferred← citeshttps://doi.org/10.1002/eji.201747092openalex-snapshot
Protein tyrosine phosphatase PTPN22 regulates IL‐1β dependent Th17 responses by modulating dectin‐1 signaling in mice
inferred← citeshttps://doi.org/10.1002/eji.201848054openalex-snapshot
Cellular and molecular mechanisms of antifungal innate immunity at epithelial barriers: The role of C‐type lectin receptors
inferred← citeshttps://doi.org/10.1002/eji.70199openalex-snapshot
SYK Signalling in NLRP3 Inflammasome‐Mediated Response of Murine Microglia Activated by Immune Complexes Formed of Viral Proteins and Specific IgG
inferred← citeshttps://doi.org/10.1002/emmm.201201771openalex-snapshot
Of inflammasomes and pathogens – sensing of microbes by the inflammasome
inferred← citeshttps://doi.org/10.1002/glia.21243openalex-snapshot
Toll‐like receptor 2 (TLR2)‐TLR9 crosstalk dictates IL‐12 family cytokine production in microglia
inferred← citeshttps://doi.org/10.1002/hep.28680openalex-snapshot
Inhibition of spleen tyrosine kinase activation ameliorates inflammation, cell death, and steatosis in alcoholic liver disease
inferred← citeshttps://doi.org/10.1002/ibd.22859openalex-snapshot
Implications of Protein Post-Translational Modifications in IBD
inferred← citeshttps://doi.org/10.1002/jlb.2ma0820-259ropenalex-snapshot
Malassezia spp. induce inflammatory cytokines and activate NLRP3 inflammasomes in phagocytes
inferred← citeshttps://doi.org/10.1002/jlb.3a0819-207rropenalex-snapshot
Syk-dependent glycolytic reprogramming in dendritic cells regulates IL-1β production to β-glucan ligands in a TLR-independent manner
inferred← citeshttps://doi.org/10.1002/jlb.3mir0917-350ropenalex-snapshot
An update on cell intrinsic negative regulators of the NLRP3 inflammasome
inferred← citeshttps://doi.org/10.1002/mbo3.70401openalex-snapshot
Malassezia May Contribute to Basal Cell Carcinoma Development via Inflammatory and Oxidative Stress Pathways
inferred← citeshttps://doi.org/10.1002/mco2.391openalex-snapshot
Inflammasome: structure, biological functions, and therapeutic targets
inferred← citeshttps://doi.org/10.1002/mnfr.201500316openalex-snapshot
Curcumin suppresses NLRP3 inflammasome activation and protects against LPS‐induced septic shock
inferred← citeshttps://doi.org/10.1002/ptr.7874openalex-snapshot
The molecular mechanisms underlying anti‐inflammatory effects of galangin in different diseases
inferred← citeshttps://doi.org/10.1002/wsbm.1639openalex-snapshot
The yeast–human coevolution: Fungal transition from passengers, colonizers, and invaders
inferred← citeshttps://doi.org/10.1007/82_2016_13openalex-snapshot
Subversion of Cell-Autonomous Host Defense by Chlamydia Infection
inferred← citeshttps://doi.org/10.1007/82_2020_197openalex-snapshot
C-type Lectins in Immunity to Lung Pathogens
inferred← citeshttps://doi.org/10.1007/82_2020_201openalex-snapshot
PAMPs of the Fungal Cell Wall and Mammalian PRRs
inferred← citeshttps://doi.org/10.1007/82_2020_211openalex-snapshot
Physiological and Pathological Functions of CARD9 Signaling in the Innate Immune System
inferred← citeshttps://doi.org/10.1007/82_2020_229openalex-snapshot
Subversion of Programed Cell Death by Poxviruses
inferred← citeshttps://doi.org/10.1007/978-1-0716-3350-2_12openalex-snapshot
Methods to Activate the NLRP3 Inflammasome
inferred← citeshttps://doi.org/10.1007/978-1-4614-1680-7_5openalex-snapshot
Intracellular Inflammatory Sensors for Foreign Invaders and Substances of Self-Origin
inferred← citeshttps://doi.org/10.1007/978-1-4614-6819-6_2openalex-snapshot
Inflammasomes and Obesity
inferred← citeshttps://doi.org/10.1007/978-1-61779-527-5_15openalex-snapshot
Measuring the Inflammasome
inferred← citeshttps://doi.org/10.1007/978-3-030-37297-2_12openalex-snapshot
Antioxidant Therapeutic Defenses Toward Redox Biology and Oxidative Stress
inferred← citeshttps://doi.org/10.1007/978-3-030-44436-5_4openalex-snapshot
Signaling Pathways Governing Activation of Innate Immune Cells
inferred← citeshttps://doi.org/10.1007/978-3-031-64853-3_8openalex-snapshot
Mammalian Pattern Recognition Receptors (PRRs) Involved in Recognition of Fungi
inferred← citeshttps://doi.org/10.1007/978-3-031-85340-1_9openalex-snapshot
Antifungal Innate Immunity
inferred← citeshttps://doi.org/10.1007/978-3-0348-0148-5_13openalex-snapshot
Activation and Regulation of the NLRP3 Inflammasome
inferred← citeshttps://doi.org/10.1007/978-3-0348-0148-5_2openalex-snapshot
Pyroptosis: A Caspase-1-Dependent Programmed Cell Death and a Barrier to Infection
inferred← citeshttps://doi.org/10.1007/978-3-0348-0148-5_3openalex-snapshot
Activation of the Inflammasome by Bacterial Pathogens
inferred← citeshttps://doi.org/10.1007/978-3-0348-0148-5_5openalex-snapshot
Inflammasome Activation in Response to Eukaryotic Pathogens
inferred← citeshttps://doi.org/10.1007/978-3-0348-0148-5_6openalex-snapshot
Inflammasome Activation by Pathogenic Crystals and Particles
inferred← citeshttps://doi.org/10.1007/978-3-319-11912-0_7openalex-snapshot
Models of Experimental Sporotrichosis and Immune Response Against Sporothrix schenckii
inferred← citeshttps://doi.org/10.1007/978-3-319-30079-5_4openalex-snapshot
Interplay Between Autophagy and Inflammasomes
inferred← citeshttps://doi.org/10.1007/978-3-319-41171-2_1openalex-snapshot
General Strategies in Inflammasome Biology
inferred← citeshttps://doi.org/10.1007/978-3-319-50409-4_9openalex-snapshot
Host Immune Responses During Infections with Candida albicans
inferred← citeshttps://doi.org/10.1007/978-3-319-50842-9_2openalex-snapshot
Immunity to Fungal Infections
inferred← citeshttps://doi.org/10.1007/978-3-319-98890-0_9openalex-snapshot
The Role of the Mycobiota in the Gut-Liver Axis
inferred← citeshttps://doi.org/10.1007/978-3-642-39432-4_4openalex-snapshot
4 Receptor–Ligand Interactions in Fungal Infections
inferred← citeshttps://doi.org/10.1007/978-3-642-39432-4_9openalex-snapshot
9 Mucosal Immunology in Candida albicans Infection
inferred← citeshttps://doi.org/10.1007/978-4-431-56015-9_8openalex-snapshot
Regulation and Function of the Inhibitory C-Type Lectin Clec12A/MICL
inferred← citeshttps://doi.org/10.1007/978-4-431-56068-5_49openalex-snapshot
The Role of Innate Immunity in Ischemic Stroke
inferred← citeshttps://doi.org/10.1007/978-981-97-5165-5_9openalex-snapshot
Clinical Significance, Molecular Formation, and Natural Antibiofilm Agents of Candida albicans
inferred← citeshttps://doi.org/10.1007/s00005-010-0082-1openalex-snapshot
Recent Developments in Immune Activation by Uric Acid Crystals
inferred← citeshttps://doi.org/10.1007/s00011-012-0555-2openalex-snapshot
Lipopolysaccharide/adenosine triphosphate-mediated signal transduction in the regulation of NLRP3 protein expression and caspase-1-mediated interleukin-1β secretion
inferred← citeshttps://doi.org/10.1007/s00011-016-0981-7openalex-snapshot
NLRP3 inflammasome: a promising target in ischemic stroke
inferred← citeshttps://doi.org/10.1007/s00011-023-01790-4openalex-snapshot
Role of NLRP3 inflammasome-mediated neuronal pyroptosis and neuroinflammation in neurodegenerative diseases
inferred← citeshttps://doi.org/10.1007/s00018-010-0290-1openalex-snapshot
Control of infection by pyroptosis and autophagy: role of TLR and NLR
inferred← citeshttps://doi.org/10.1007/s00018-010-0335-5openalex-snapshot
Control of infection by pyroptosis and autophagy: role of TLR and NLR
inferred← citeshttps://doi.org/10.1007/s00018-010-0567-4openalex-snapshot
Inflammasomes: current understanding and open questions
inferred← citeshttps://doi.org/10.1007/s00018-013-1425-yopenalex-snapshot
IL-18 in inflammatory and autoimmune disease
inferred← citeshttps://doi.org/10.1007/s00018-016-2396-6openalex-snapshot
Assembly and regulation of ASC specks
inferred← citeshttps://doi.org/10.1007/s00109-010-0631-4openalex-snapshot
SYK kinase signaling and the NLRP3 inflammasome in antifungal immunity
inferred← citeshttps://doi.org/10.1007/s00109-015-1320-0openalex-snapshot
Nlrp1 inflammasome is downregulated in trauma patients
inferred← citeshttps://doi.org/10.1007/s00204-021-02993-6openalex-snapshot
Ochratoxin A induces nephrotoxicity in vitro and in vivo via pyroptosis
inferred← citeshttps://doi.org/10.1007/s00239-026-10307-6openalex-snapshot
Conservation of NLRP3 Inflammasome Pathway in Monotremes and Large-Scale Restructuring of the Caspase-1 Gene Cluster Region in Mammals
inferred← citeshttps://doi.org/10.1007/s00281-014-0462-4openalex-snapshot
Pattern recognition receptors in antifungal immunity
inferred← citeshttps://doi.org/10.1007/s00281-014-0467-zopenalex-snapshot
Antifungal innate immunity: recognition and inflammatory networks
inferred← citeshttps://doi.org/10.1007/s00281-014-0471-3openalex-snapshot
Immune responses to airborne fungi and non-invasive airway diseases
inferred← citeshttps://doi.org/10.1007/s00281-015-0518-0openalex-snapshot
β-amyloid, microglia, and the inflammasome in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1007/s00394-015-1113-9openalex-snapshot
Relation between neonatal malnutrition and gene expression: inflammasome function in infections caused by Candida Albicans
inferred← citeshttps://doi.org/10.1007/s10753-016-0461-9openalex-snapshot
Genetic Phagocyte NADPH Oxidase Deficiency Enhances Nonviable Candida albicans–Induced Inflammation in Mouse Lungs
inferred← citeshttps://doi.org/10.1007/s10753-017-0613-6openalex-snapshot
Deficiency of NALP3 Signaling Impairs Liver Regeneration After Partial Hepatectomy
inferred← citeshttps://doi.org/10.1007/s10753-017-0674-6openalex-snapshot
Fungal β-Glucan Activates the NLRP3 Inflammasome in Human Bronchial Epithelial Cells Through ROS Production
inferred← citeshttps://doi.org/10.1007/s10753-020-01301-1openalex-snapshot
Understanding the Role of Inflammasomes in Rheumatoid Arthritis
inferred← citeshttps://doi.org/10.1007/s10753-023-01903-5openalex-snapshot
MDA5 Enhances Invasive Candida albicans Infection by Regulating Macrophage Apoptosis and Phagocytosis/Killing Functions
inferred← citeshttps://doi.org/10.1007/s10875-010-9385-6openalex-snapshot
ITAM Receptor Signaling and the NLRP3 Inflammasome in Antifungal Immunity
inferred← citeshttps://doi.org/10.1007/s10875-010-9431-4openalex-snapshot
Inflammasomes and Anti-Viral Immunity
inferred← citeshttps://doi.org/10.1007/s10875-010-9440-3openalex-snapshot
Molecular Mechanism of NLRP3 Inflammasome Activation
inferred← citeshttps://doi.org/10.1007/s11046-017-0210-0openalex-snapshot
The Expression of Dectin-1, Irak1 and Rip2 During the Host Response to Aspergillus fumigatus
inferred← citeshttps://doi.org/10.1007/s11427-024-2645-yopenalex-snapshot
FHL2 deficiency aggravates Candida albicans infection through decreased myelopoiesis
inferred← citeshttps://doi.org/10.1007/s11882-016-0643-4openalex-snapshot
Innate Immune Responses to Fungal Allergens
inferred← citeshttps://doi.org/10.1007/s12026-011-8226-xopenalex-snapshot
IL-17 signaling in host defense against Candida albicans
inferred← citeshttps://doi.org/10.1007/s12026-012-8265-yopenalex-snapshot
Complexity and dynamics of host–fungal interactions
inferred← citeshttps://doi.org/10.1007/s12026-012-8272-zopenalex-snapshot
The rhapsody of NLRPs: master players of inflammation … and a lot more
inferred← citeshttps://doi.org/10.1007/s12026-012-8317-3openalex-snapshot
Effector functions of NLRs in the intestine: innate sensing, cell death, and disease
inferred← citeshttps://doi.org/10.1007/s12035-025-05472-6openalex-snapshot
Chronic Styrene Exposure Causes Oxidative Stress, Neuroinflammation, and Hippocampal Memory Dysfunction via NLRP3 Inflammasome Activation
inferred← citeshttps://doi.org/10.1007/s12264-013-1328-9openalex-snapshot
Research progress on the NLRP3 inflammasome and its role in the central nervous system
inferred← citeshttps://doi.org/10.1007/s12281-011-0065-7openalex-snapshot
The Role of Genetics in Host Responses to Mucosal and Invasive Candidiasis
inferred← citeshttps://doi.org/10.1007/s12281-013-0130-5openalex-snapshot
Arming Th17 Cells for Antifungal Host Defense
inferred← citeshttps://doi.org/10.1007/s12664-023-01510-0openalex-snapshot
A comprehensive guide to assess gut mycobiome and its role in pathogenesis and treatment of inflammatory bowel disease
inferred← citeshttps://doi.org/10.1007/s12975-020-00840-xopenalex-snapshot
TREM-1 Exacerbates Neuroinflammatory Injury via NLRP3 Inflammasome-Mediated Pyroptosis in Experimental Subarachnoid Hemorrhage
inferred← citeshttps://doi.org/10.1007/s13238-013-2113-2openalex-snapshot
Cellular localization of NLRP3 inflammasome
inferred← citeshttps://doi.org/10.1007/s13238-013-2127-9openalex-snapshot
Human pathogenic fungus Trichophyton schoenleinii activates the NLRP3 inflammasome
inferred← citeshttps://doi.org/10.1007/s13238-013-2128-8openalex-snapshot
Negative regulation of NLRP3 inflammasome signaling
inferred← citeshttps://doi.org/10.1016/b978-0-12-394802-1.00005-4openalex-snapshot
Phagocytes and Immunoglobulins
inferred← citeshttps://doi.org/10.1016/b978-0-12-396548-6.00007-xopenalex-snapshot
TLR Ligand–Peptide Conjugate Vaccines
inferred← citeshttps://doi.org/10.1016/b978-0-12-405546-9.00024-8openalex-snapshot
Classic Autoinflammatory Diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-809633-8.12075-8openalex-snapshot
Immune Response to Candida albicans Infection
inferred← citeshttps://doi.org/10.1016/b978-0-12-816768-7.00028-4openalex-snapshot
IL-1 mediated autoinflammatory diseases
inferred← citeshttps://doi.org/10.1016/b978-0-12-818006-8.00007-4openalex-snapshot
Infection and Immunity
inferred← citeshttps://doi.org/10.1016/b978-0-12-822481-6.00023-2openalex-snapshot
Effects of interactions between antioxidant defense therapy and ROS
inferred← citeshttps://doi.org/10.1016/b978-0-323-91146-7.00010-xopenalex-snapshot
Dendritic cells as vaccine targets
inferred← citeshttps://doi.org/10.1016/b978-1-4377-2662-6.00012-2openalex-snapshot
Neonatal T Cell Immunity and Its Regulation by Innate Immunity and Dendritic Cells
inferred← citeshttps://doi.org/10.1016/bs.apha.2024.10.004openalex-snapshot
Biological and therapeutic significance of targeting NLRP3 inflammasome in the brain and the current efforts to develop brain-penetrant inhibitors
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2019.11.005openalex-snapshot
Regulation of cell death in the cardiovascular system
inferred← citeshttps://doi.org/10.1016/bs.mie.2019.07.008openalex-snapshot
Protein interactions of the inflammasome adapter ASC by solution NMR
inferred← citeshttps://doi.org/10.1016/j.abb.2019.05.023openalex-snapshot
Structure, interactions and self-assembly of ASC-dependent inflammasomes
inferred← citeshttps://doi.org/10.1016/j.acthis.2014.05.008openalex-snapshot
NLRP3 inflammasome is required for apoptosis of Aggregatibacter actinomycetemcomitans-infected human osteoblastic MG63 cells
inferred← citeshttps://doi.org/10.1016/j.addr.2023.114775openalex-snapshot
Fungal infections: Immune defense, immunotherapies and vaccines
inferred← citeshttps://doi.org/10.1016/j.ajpath.2013.09.007openalex-snapshot
New Insights into Mechanisms Controlling the NLRP3 Inflammasome and Its Role in Lung Disease
inferred← citeshttps://doi.org/10.1016/j.ajpath.2014.03.012openalex-snapshot
Inflammasome Activation Is Reactive Oxygen Species Dependent and Mediates Irinotecan-Induced Mucositis through IL-1β and IL-18 in Mice
inferred← citeshttps://doi.org/10.1016/j.ajpath.2017.12.010openalex-snapshot
Spliceosome-Associated Protein 130 Exacerbates Alcohol-Induced Liver Injury by Inducing NLRP3 Inflammasome–Mediated IL-1β in Mice
inferred← citeshttps://doi.org/10.1016/j.ajpath.2020.02.006openalex-snapshot
Complement Membrane Attack Complex
inferred← citeshttps://doi.org/10.1016/j.anireprosci.2015.11.004openalex-snapshot
Knockdown of NLRP5 arrests early embryogenesis in sows
inferred← citeshttps://doi.org/10.1016/j.arr.2013.09.004openalex-snapshot
Pathogenesis of acute stroke and the role of inflammasomes
inferred← citeshttps://doi.org/10.1016/j.arr.2015.01.003openalex-snapshot
DAMPs as mediators of sterile inflammation in aging-related pathologies
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2019.08.017openalex-snapshot
Inhibition of vascular neointima hyperplasia by FGF21 associated with FGFR1/Syk/NLRP3 inflammasome pathway in diabetic mice
inferred← citeshttps://doi.org/10.1016/j.bbcan.2020.188489openalex-snapshot
Gut mycobiome: A promising target for colorectal cancer
inferred← citeshttps://doi.org/10.1016/j.bbi.2016.11.004openalex-snapshot
Human albumin attenuates excessive innate immunity via inhibition of microglial Mincle/Syk signaling in subarachnoid hemorrhage
inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.03.021openalex-snapshot
The oxindole Syk inhibitor OXSI-2 blocks nigericin-induced inflammasome signaling and pyroptosis independent of potassium efflux
inferred← citeshttps://doi.org/10.1016/j.bcp.2020.114201openalex-snapshot
Perillaldehyde: A promising antifungal agent to treat oropharyngeal candidiasis
inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114861openalex-snapshot
Luxeptinib disables NLRP3 inflammasome-mediated IL-1β release and pathways required for secretion of inflammatory cytokines IL-6 and TNFα
inferred← citeshttps://doi.org/10.1016/j.biocel.2010.01.008openalex-snapshot
Nlrp3: An immune sensor of cellular stress and infection
inferred← citeshttps://doi.org/10.1016/j.biocel.2016.03.001openalex-snapshot
Inhibition of spleen tyrosine kinase (syk) suppresses renal fibrosis through anti-inflammatory effects and down regulation of the MAPK-p38 pathway
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115393openalex-snapshot
Role of the NLRP3 inflammasome in gynecological disease
inferred← citeshttps://doi.org/10.1016/j.bj.2016.07.001openalex-snapshot
Danger signals, inflammasomes, and the intricate intracellular lives of chlamydiae
inferred← citeshttps://doi.org/10.1016/j.brainres.2012.04.058openalex-snapshot
Pannexin: From discovery to bedside in 11±4 years?
inferred← citeshttps://doi.org/10.1016/j.canlet.2016.06.004openalex-snapshot
The innate immune signaling in cancer and cardiometabolic diseases: Friends or foes?
inferred← citeshttps://doi.org/10.1016/j.cell.2009.08.039openalex-snapshot
Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells
inferred← citeshttps://doi.org/10.1016/j.cell.2010.02.043openalex-snapshot
Anti-inflammatory Agents: Present and Future
inferred← citeshttps://doi.org/10.1016/j.cellimm.2011.04.002openalex-snapshot
Regulation of NLRP3 and AIM2 inflammasome gene expression levels in gingival fibroblasts by oral biofilms
inferred← citeshttps://doi.org/10.1016/j.cellimm.2025.104961openalex-snapshot
The NLRP3 Inflammasome in inflammatory diseases: Cellular dynamics and role in granuloma formation
inferred← citeshttps://doi.org/10.1016/j.cellsig.2024.111418openalex-snapshot
Molecular mechanisms of zymosan-induced inflammasome activation in macrophages
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.11.018openalex-snapshot
Vav Proteins Are Key Regulators of Card9 Signaling for Innate Antifungal Immunity
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.110414openalex-snapshot
Listeria toxin promotes phosphorylation of the inflammasome adaptor ASC through Lyn and Syk to exacerbate pathogen expansion
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111374openalex-snapshot
The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.112522openalex-snapshot
Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115694openalex-snapshot
IRE1α promotes phagosomal calcium flux to enhance macrophage fungicidal activity
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115839openalex-snapshot
Piezo1 senses hyphae and initiates host defense against pathogenic fungi
inferred← citeshttps://doi.org/10.1016/j.chom.2009.05.002openalex-snapshot
An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans
inferred← citeshttps://doi.org/10.1016/j.chom.2011.04.005openalex-snapshot
Restoration of Pattern Recognition Receptor Costimulation to Treat Chromoblastomycosis, a Chronic Fungal Infection of the Skin
inferred← citeshttps://doi.org/10.1016/j.chom.2012.04.008openalex-snapshot
Th17 Cells in Immunity to Candida albicans
inferred← citeshttps://doi.org/10.1016/j.chom.2015.01.006openalex-snapshot
Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection
inferred← citeshttps://doi.org/10.1016/j.chom.2015.02.007openalex-snapshot
Pathogenic Fungi Regulate Immunity by Inducing Neutrophilic Myeloid-Derived Suppressor Cells
inferred← citeshttps://doi.org/10.1016/j.chom.2015.02.017openalex-snapshot
Inflammasomes in Aspergillosis—It Takes Two to Tango
inferred← citeshttps://doi.org/10.1016/j.chom.2015.07.004openalex-snapshot
Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra
inferred← citeshttps://doi.org/10.1016/j.chom.2015.07.016openalex-snapshot
Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium
inferred← citeshttps://doi.org/10.1016/j.chom.2016.12.004openalex-snapshot
The Bacterial T6SS Effector EvpP Prevents NLRP3 Inflammasome Activation by Inhibiting the Ca2+-Dependent MAPK-Jnk Pathway
inferred← citeshttps://doi.org/10.1016/j.chom.2020.09.004openalex-snapshot
Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection
inferred← citeshttps://doi.org/10.1016/j.chom.2024.07.003openalex-snapshot
A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1
inferred← citeshttps://doi.org/10.1016/j.clim.2013.01.006openalex-snapshot
Contribution of the inflammasomes to autoinflammatory diseases and recent mouse models as research tools
inferred← citeshttps://doi.org/10.1016/j.cmet.2015.03.012openalex-snapshot
Inflammasome Inhibition: Putting Out the Fire
inferred← citeshttps://doi.org/10.1016/j.coi.2009.12.004openalex-snapshot
The inflammasomes: mechanisms of activation and function
inferred← citeshttps://doi.org/10.1016/j.coi.2011.07.005openalex-snapshot
Cross-regulation between the IL-1β/IL-18 processing inflammasome and other inflammatory cytokines
inferred← citeshttps://doi.org/10.1016/j.coi.2012.12.004openalex-snapshot
Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developments
inferred← citeshttps://doi.org/10.1016/j.csbj.2022.10.019openalex-snapshot
From structure to function – Ligand recognition by myeloid C-type lectin receptors
inferred← citeshttps://doi.org/10.1016/j.cyto.2011.08.031openalex-snapshot
C-type lectin receptors and cytokines in fungal immunity
inferred← citeshttps://doi.org/10.1016/j.cyto.2012.03.016openalex-snapshot
Aggregatibacter actinomycetemcomitans targets NLRP3 and NLRP6 inflammasome expression in human mononuclear leukocytes
inferred← citeshttps://doi.org/10.1016/j.cyto.2016.05.015openalex-snapshot
New advances in invasive aspergillosis immunobiology leading the way towards personalized therapeutic approaches
inferred← citeshttps://doi.org/10.1016/j.cyto.2017.05.015openalex-snapshot
The Goldilocks model of immune symbiosis with Mycobacteria and Candida colonizers
inferred← citeshttps://doi.org/10.1016/j.cyto.2023.156302openalex-snapshot
TRAF6-TAK1-IKKβ pathway mediates TLR2 agonists activating “one-step” NLRP3 inflammasome in human monocytes
inferred← citeshttps://doi.org/10.1016/j.cyto.2026.157125openalex-snapshot
The emerging role of interleukin-41: a novel biomarker and therapeutic target in inflammation and immune-related diseases
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2011.09.003openalex-snapshot
NOD-like receptors and the innate immune system: Coping with danger, damage and death
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2014.07.020openalex-snapshot
Inflammasome activation and metabolic disease progression
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2026.05.001openalex-snapshot
Mitochondrial DNA-mediated cGAS–STING activation and its crosstalk with NLRP3 inflammasome in chronic obstructive pulmonary disease
inferred← citeshttps://doi.org/10.1016/j.dci.2020.103874openalex-snapshot
The neutrophil inflammasome
inferred← citeshttps://doi.org/10.1016/j.devcel.2016.06.023openalex-snapshot
Diffusion Barriers, Mechanical Forces, and the Biophysics of Phagocytosis
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.116282openalex-snapshot
Nod-like receptor protein 3 inflammasome-mediated pyroptosis contributes to chronic NaAsO2 exposure-induced fibrotic changes and dysfunction in the liver of SD rats
inferred← citeshttps://doi.org/10.1016/j.ejpb.2026.115209openalex-snapshot
β-glucan particles as oral carriers for a dual-antigen hepatitis B vaccine: Liver targeting and immune potentiation following subcutaneous priming
inferred← citeshttps://doi.org/10.1016/j.exppara.2026.109197openalex-snapshot
Therapeutic effect of curdlan in experimental visceral leishmaniasis is mediated by activation of NLRP3 inflammasome
inferred← citeshttps://doi.org/10.1016/j.febslet.2011.09.033openalex-snapshot
Two non-vesicular ATP release pathways in the mouse erythrocyte membrane
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2011.05.016openalex-snapshot
Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2022.01.004openalex-snapshot
Spleen tyrosine kinase regulates keratinocyte inflammasome activation and skin inflammation induced by UVB irradiation
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2023.07.010openalex-snapshot
Ox-inflammasome involvement in neuroinflammation
inferred← citeshttps://doi.org/10.1016/j.fsi.2025.110607openalex-snapshot
The activation of NLRP3 inflammasome and its function in anti-infection immunity of largemouth bass (Micropterus salmoides)
inferred← citeshttps://doi.org/10.1016/j.fsirep.2023.100085openalex-snapshot
Syk regulates the haemocyte autophagy through inducing the mRNA expressions of autophagy-related genes and the cleavage of CgLC3 in oyster antibacterial immunity
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e38139openalex-snapshot
Deletion of Card9 eliminates the detrimental facets of mycobacterial adjuvants
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