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Piezo2 is required for Merkel-cell mechanotransduction

https://doi.org/10.1038/nature13251
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ar.a.10029openalex-snapshot
Friedrich Sigmund Merkel and his “Merkel cell”, morphology, development, and physiology: Review and new results
inferredcites →https://doi.org/10.1007/bf00229133openalex-snapshot
Selective phototoxic destruction of quinacrine-loaded Merkel cells is neither selective nor complete
inferredcites →https://doi.org/10.1007/bf01181555openalex-snapshot
Merkel cells are not the mechanosensory transducers in the touch dome of the rat
inferredcites →https://doi.org/10.1007/s00424-008-0496-3openalex-snapshot
Voltage-activated ion channels and Ca2+-induced Ca2+ release shape Ca2+ signaling in Merkel cells
inferredcites →https://doi.org/10.1016/j.celrep.2012.07.014openalex-snapshot
Inflammatory Signals Enhance Piezo2-Mediated Mechanosensitive Currents
inferredcites →https://doi.org/10.1016/j.neuron.2009.10.023openalex-snapshot
Math1 Is Essential for the Development of Hindbrain Neurons Critical for Perinatal Breathing
inferredcites →https://doi.org/10.1016/j.neuron.2013.07.051openalex-snapshot
The Sensory Neurons of Touch
inferredcites →https://doi.org/10.1016/j.neuroscience.2009.07.015openalex-snapshot
Non-competitive metabotropic glutamate 1 receptor antagonists block activity of slowly adapting type I mechanoreceptor units in the rat sinus hair follicle
inferredcites →https://doi.org/10.1016/s0959-4388(00)00234-8openalex-snapshot
The roles and functions of cutaneous mechanoreceptors
inferredcites →https://doi.org/10.1038/nature10801openalex-snapshot
The role of Drosophila Piezo in mechanical nociception
inferredcites →https://doi.org/10.1038/nature10812openalex-snapshot
Piezo proteins are pore-forming subunits of mechanically activated channels
inferredcites →https://doi.org/10.1038/nature13250openalex-snapshot
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors
inferredcites →https://doi.org/10.1046/j.1460-9568.1999.00822.xopenalex-snapshot
Postnatal loss of Merkel cells, but not of slowly adapting mechanoreceptors in mice lacking the neurotrophin receptor p75
inferredcites →https://doi.org/10.1097/00001756-200102120-00032openalex-snapshot
Evidence for glutamate receptor mediated transmission at mechanoreceptors in the skin
inferredcites →https://doi.org/10.1111/1523-1747.ep12522555openalex-snapshot
Fine Structural Analysis of the Synaptic Junction of Merkel Cell-Axon-Complexes
inferredcites →https://doi.org/10.1111/nyas.12057openalex-snapshot
Neurotransmitters and synaptic components in the Merkel cell–neurite complex, a gentle‐touch receptor
inferredcites →https://doi.org/10.1113/jphysiol.1967.sp008339openalex-snapshot
COMMUNICATIONS
inferredcites →https://doi.org/10.1113/jphysiol.1969.sp008721openalex-snapshot
The structure and function of a slowly adapting touch corpuscle in hairy skin
inferredcites →https://doi.org/10.1113/jphysiol.1986.sp016144openalex-snapshot
Are Merkel cell‐neurite reciprocal synapses involved in the initiation of tactile responses in salamander skin?
inferredcites →https://doi.org/10.1113/jphysiol.1992.sp019120openalex-snapshot
Voltage‐dependent currents in isolated single Merkel cells of rats.
inferredcites →https://doi.org/10.1113/jphysiol.1994.sp020292openalex-snapshot
Selective phototoxic destruction of rat Merkel cells abolishes responses of slowly adapting type I mechanoreceptor units.
inferredcites →https://doi.org/10.1126/science.1172890openalex-snapshot
Merkel Cells Are Essential for Light-Touch Responses
inferredcites →https://doi.org/10.1126/science.1193270openalex-snapshot
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
inferredcites →https://doi.org/10.1152/jn.00810.2009openalex-snapshot
The Regularity of Sustained Firing Reveals Two Populations of Slowly Adapting Touch Receptors in Mouse Hairy Skin
inferredcites →https://doi.org/10.1152/jn.1997.78.4.1841openalex-snapshot
Receptive Properties of Mouse Sensory Neurons Innervating Hairy Skin
inferredcites →https://doi.org/10.1152/jn.90799.2008openalex-snapshot
Speed and Temperature Dependences of Mechanotransduction in Afferent Fibers Recorded From the Mouse Saphenous Nerve
inferredcites →https://doi.org/10.1186/1744-8069-3-40openalex-snapshot
A Role of TRPA1 in Mechanical Hyperalgesia is Revealed by Pharmacological Inhibition
inferredcites →https://doi.org/10.1242/dev.055970openalex-snapshot
Identification of epidermal progenitors for the Merkel cell lineage
inferredcites →https://doi.org/10.1242/dev.127.22.4775openalex-snapshot
Sonic hedgehog regulates growth and morphogenesis of the tooth
inferredcites →https://doi.org/10.1523/jneurosci.0522-13.2013openalex-snapshot
piezo2bRegulates Vertebrate Light Touch Response
inferredcites →https://doi.org/10.1523/jneurosci.19-19-08509.1999openalex-snapshot
Overexpression of Nerve Growth Factor in Skin Selectively Affects the Survival and Functional Properties of Nociceptors
inferredcites →https://doi.org/10.1523/jneurosci.5307-11.2012openalex-snapshot
Rodents Rely on Merkel Cells for Texture Discrimination Tasks
inferredcites →https://doi.org/10.3109/08990220.2010.516670openalex-snapshot
Evidence of fast serotonin transmission in frog slowly adapting type 1 responses
inferredcites →https://doi.org/10.3109/08990229109144732openalex-snapshot
Slowly Adapting Cutaneous Mechanoreceptor Afferent Units Associated with Merkel Cells in Frogs and Effects of Direct Currents
inferredcites →https://doi.org/10.7554/elife.01488openalex-snapshot
Computation identifies structural features that govern neuronal firing properties in slowly adapting touch receptors

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/9780470015902.a0029142openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/9780470015902.a0029276openalex-snapshot
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Pathophysiology of Pain
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Mimicking Human and Biological Skins for Multifunctional Skin Electronics
inferred← citeshttps://doi.org/10.1002/adfm.201904532openalex-snapshot
Ionic Tactile Sensors for Emerging Human‐Interactive Technologies: A Review of Recent Progress
inferred← citeshttps://doi.org/10.1002/adfm.202516545openalex-snapshot
Near‐Sensor Analog Computing via Monolithic 3D Piezoelectric Sensor–FeFET for Tactile Sensing System
inferred← citeshttps://doi.org/10.1002/adfm.78465openalex-snapshot
A Stretchable Organic Electrochemical Transistor Mechano‐Synapse With Biomimetic Mechanotransduction for Intelligent Soft Electronic Skin
inferred← citeshttps://doi.org/10.1002/adhm.71400openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/adma.201605973openalex-snapshot
An Ultrasensitive, Visco‐Poroelastic Artificial Mechanotransducer Skin Inspired by Piezo2 Protein in Mammalian Merkel Cells
inferred← citeshttps://doi.org/10.1002/adma.201706299openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/adma.202403830openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/adsr.202500155openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/advs.202506738openalex-snapshot
Organoid Modeling of Mouse Anterior Tongue Epithelium Reveals Regional and Cellular Identities
inferred← citeshttps://doi.org/10.1002/ajmg.a.61143openalex-snapshot
Distal arthrogryposis type 5 and PIEZO2 novel variant in a Canadian family
inferred← citeshttps://doi.org/10.1002/ar.25351openalex-snapshot
Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament
inferred← citeshttps://doi.org/10.1002/brx2.70006openalex-snapshot
Mechanosensitive Piezo channels and their potential roles in peripheral auditory perception
inferred← citeshttps://doi.org/10.1002/cbic.202100416openalex-snapshot
Stimuli‐Responsive Natural Proteins and Their Applications
inferred← citeshttps://doi.org/10.1002/cne.70186openalex-snapshot
Anatomical Characteristics of Tongue‐Innervating Mechanoreceptors
inferred← citeshttps://doi.org/10.1002/cphy.c210020openalex-snapshot
Control of Mammalian Locomotion by Somatosensory Feedback
inferred← citeshttps://doi.org/10.1002/cphy.c220024openalex-snapshot
Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation
inferred← citeshttps://doi.org/10.1002/glia.24251openalex-snapshot
Piezo channels contribute to the regulation of myelination in Schwann cells
inferred← citeshttps://doi.org/10.1002/glia.24334openalex-snapshot
Mechanosensitive channel Piezo1 is an essential regulator in cell cycle progression of optic nerve head astrocytes
inferred← citeshttps://doi.org/10.1002/glia.70199openalex-snapshot
A Microglia–Astrocyte Signaling Axis Regulates Astrocyte Piezo1 Expression and Inflammatory Responses
inferred← citeshttps://doi.org/10.1002/glia.70204openalex-snapshot
Müller Glia–Vasculature Interactions in the Developing Retina
inferred← citeshttps://doi.org/10.1002/hed.24359openalex-snapshot
Merkel cell carcinoma: Do you know your guidelines?
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2022.tb00203.xopenalex-snapshot
Control of Mammalian Locomotion by Somatosensory Feedback
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2023.tb00272.xopenalex-snapshot
Serotonergic Control of Gastrointestinal Development, Motility, and Inflammation
inferred← citeshttps://doi.org/10.1002/jbmr.4198openalex-snapshot
Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation
inferred← citeshttps://doi.org/10.1002/jlb.mr0718-267ropenalex-snapshot
Lymphocyte mechanotransduction: The regulatory role of cytoskeletal dynamics in signaling cascades and effector functions
inferred← citeshttps://doi.org/10.1002/jsp2.1253openalex-snapshot
Multiplex epigenome editing of ion channel expression in nociceptive neurons abolished degenerative IVD ‐conditioned media‐induced mechanical sensitivity
inferred← citeshttps://doi.org/10.1002/mabi.202000147openalex-snapshot
All‐Printed Electronic Skin Based on Deformable and Ionic Mechanotransducer Array
inferred← citeshttps://doi.org/10.1002/path.6455openalex-snapshot
Increased expression of the PIEZO2 mechanoreceptor in fibroblasts and endothelial cells within the lymphatic and vascular vessels of keloids
inferred← citeshttps://doi.org/10.1002/prot.25384openalex-snapshot
Investigating the structural dynamics of the PIEZO1 channel activation and inactivation by coarse‐grained modeling
inferred← citeshttps://doi.org/10.1002/smll.202100804openalex-snapshot
Micro‐Nano Processing of Active Layers in Flexible Tactile Sensors via Template Methods: A Review
inferred← citeshttps://doi.org/10.1002/smll.202403629openalex-snapshot
Nanofluidic Membrane‐Assisted Organic Electrochemical Transistors for Bioinspired Gustatory Sensation Based on Selective Cation Transport
inferred← citeshttps://doi.org/10.1002/smll.202501862openalex-snapshot
Dynamic Hydrogels with Tunable Mechanics for 3D Organoid Derivation
inferred← citeshttps://doi.org/10.1002/term.3196openalex-snapshot
Innervation of Meissner's corpuscles and Merkel ‐cells by transplantation of embryonic dorsal root ganglion cells after peripheral nerve section in rats
inferred← citeshttps://doi.org/10.1002/wdev.229openalex-snapshot
The specification and wiring of mammalian cutaneous low‐threshold mechanoreceptors
inferred← citeshttps://doi.org/10.1007/112_2015_26openalex-snapshot
The Piezo Mechanosensitive Ion Channels: May the Force Be with You!
inferred← citeshttps://doi.org/10.1007/112_2020_32openalex-snapshot
Calcium-Permeable Channels in Tumor Vascularization: Peculiar Sensors of Microenvironmental Chemical and Physical Cues
inferred← citeshttps://doi.org/10.1007/164_2019_336openalex-snapshot
Ion Channel Pharmacology for Pain Modulation
inferred← citeshttps://doi.org/10.1007/978-1-0716-2039-7_21openalex-snapshot
Measuring Mouse Somatosensory Reflexive Behaviors with High-Speed Videography, Statistical Modeling, and Machine Learning
inferred← citeshttps://doi.org/10.1007/978-1-4939-6418-5_3openalex-snapshot
Cell Biology of Tactile Afferents
inferred← citeshttps://doi.org/10.1007/978-1-4939-6418-5_6openalex-snapshot
The Touch Landscape
inferred← citeshttps://doi.org/10.1007/978-3-032-19509-8_3openalex-snapshot
PIEZO1 in Immune Cells: From Force to Function
inferred← citeshttps://doi.org/10.1007/978-3-319-16769-5_3openalex-snapshot
Polycomb Proteins and their Roles in Skin Development and Regeneration
inferred← citeshttps://doi.org/10.1007/978-3-319-18705-1_7openalex-snapshot
TRP Channels and Mechanical Transduction
inferred← citeshttps://doi.org/10.1007/978-3-319-28100-1_8-1openalex-snapshot
Neurophysiology of Orofacial Pain
inferred← citeshttps://doi.org/10.1007/978-3-319-28100-1_8-2openalex-snapshot
Neurophysiology of Orofacial Pain
inferred← citeshttps://doi.org/10.1007/978-3-319-28100-1_8-3openalex-snapshot
Neurophysiology of Orofacial Pain
inferred← citeshttps://doi.org/10.1007/978-3-319-41523-9_10openalex-snapshot
Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors
inferred← citeshttps://doi.org/10.1007/978-3-319-72303-7_8openalex-snapshot
Neurophysiology of Orofacial Pain
inferred← citeshttps://doi.org/10.1007/978-3-662-54117-3_15openalex-snapshot
Somatosensorik
inferred← citeshttps://doi.org/10.1007/978-3-662-57263-4_12openalex-snapshot
Das somatosensorische System
inferred← citeshttps://doi.org/10.1007/978-3-662-70359-5_7openalex-snapshot
Mechanorezeption
inferred← citeshttps://doi.org/10.1007/978-981-10-8557-4_4openalex-snapshot
Molecular Components of Mechanotransduction Machinery
inferred← citeshttps://doi.org/10.1007/978-981-13-1756-9_1openalex-snapshot
Molecular Mechanisms of the Sense of Touch: An Overview of Mechanical Transduction and Transmission in Merkel Discs of Whisker Hair Follicles and Some Clinical Perspectives
inferred← citeshttps://doi.org/10.1007/s00018-015-1853-yopenalex-snapshot
An updated review of mechanotransduction in skin disorders: transcriptional regulators, ion channels, and microRNAs
inferred← citeshttps://doi.org/10.1007/s00018-022-04622-6openalex-snapshot
Piezo1-expressing vocal fold epithelia modulate remodeling via effects on self-renewal and cytokeratin differentiation
inferred← citeshttps://doi.org/10.1007/s00132-026-04838-5openalex-snapshot
Extrakorporale Stoßwellentherapie (ESWT) in der Handchirurgie
inferred← citeshttps://doi.org/10.1007/s00424-014-1563-6openalex-snapshot
Sensory mechanotransduction at membrane-matrix interfaces
inferred← citeshttps://doi.org/10.1007/s00424-014-1569-0openalex-snapshot
Mechanotransduction in epidermal Merkel cells
inferred← citeshttps://doi.org/10.1007/s00424-014-1578-zopenalex-snapshot
Piezo channels: from structure to function
inferred← citeshttps://doi.org/10.1007/s00424-014-1651-7openalex-snapshot
Transduction and encoding sensory information by skin mechanoreceptors
inferred← citeshttps://doi.org/10.1007/s00424-020-02369-2openalex-snapshot
It takes more than two to tango: mechanosignaling of the endothelial surface
inferred← citeshttps://doi.org/10.1007/s00424-022-02667-xopenalex-snapshot
Nobel somatosensations and pain
inferred← citeshttps://doi.org/10.1007/s00441-017-2755-0openalex-snapshot
Mechanosensitive ion channel Piezo1 is expressed in antral G cells of murine stomach
inferred← citeshttps://doi.org/10.1007/s00441-018-2926-7openalex-snapshot
Piezo proteins: incidence and abundance in the enteric nervous system. Is there a link with mechanosensitivity?
inferred← citeshttps://doi.org/10.1007/s00484-018-1545-zopenalex-snapshot
Salt water and skin interactions: new lines of evidence
inferred← citeshttps://doi.org/10.1007/s11571-018-9507-zopenalex-snapshot
Neurodynamic analysis of Merkel cell–neurite complex transduction mechanism during tactile sensing
inferred← citeshttps://doi.org/10.1007/s11724-016-0480-1openalex-snapshot
Bases moléculaires de la mécanosensibilité
inferred← citeshttps://doi.org/10.1007/s12031-022-02015-9openalex-snapshot
Is the Sex Difference a Clue to the Pathomechanism of Dry Eye Disease? Watch out for the NGF-TrkA-Piezo2 Signaling Axis and the Piezo2 Channelopathy
inferred← citeshttps://doi.org/10.1007/s12264-017-0136-zopenalex-snapshot
Spinal Circuits Transmitting Mechanical Pain and Itch
inferred← citeshttps://doi.org/10.1007/s13311-020-00937-zopenalex-snapshot
Novel Analgesics with Peripheral Targets
inferred← citeshttps://doi.org/10.1007/s13577-022-00738-wopenalex-snapshot
The Piezo1 ion channel in glaucoma: a new perspective on mechanical stress
inferred← citeshttps://doi.org/10.1007/s40820-024-01550-xopenalex-snapshot
Recent Advances in Artificial Sensory Neurons: Biological Fundamentals, Devices, Applications, and Challenges
inferred← citeshttps://doi.org/10.1016/b978-0-12-800050-2.00007-3openalex-snapshot
Cellular Regulation of Peripheral Serotonin
inferred← citeshttps://doi.org/10.1016/b978-0-12-805408-6.00014-2openalex-snapshot
The Neural Mechanisms of Touch and Proprioception at the Somatosensory Periphery
inferred← citeshttps://doi.org/10.1016/b978-0-12-809324-5.00014-6openalex-snapshot
OBSOLETE: The Neural Mechanisms of Touch and Proprioception at the Somatosensory Periphery
inferred← citeshttps://doi.org/10.1016/b978-0-12-809324-5.24215-6openalex-snapshot
Molecular Biology of the Nociceptor/Transduction
inferred← citeshttps://doi.org/10.1016/b978-0-12-809633-8.08094-8openalex-snapshot
Mechanosensory Transduction: Focus on Ion Channels ☆
inferred← citeshttps://doi.org/10.1016/b978-0-12-812952-4.00013-1openalex-snapshot
Gastrointestinal mechanosensory function in health and disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-821565-4.00004-3openalex-snapshot
Glia of special senses
inferred← citeshttps://doi.org/10.1016/b978-0-12-822404-5.00004-8openalex-snapshot
General Sensory System and Taste
inferred← citeshttps://doi.org/10.1016/b978-0-323-91534-2.00014-xopenalex-snapshot
Regulation of breathing by cardiopulmonary afferents
inferred← citeshttps://doi.org/10.1016/b978-0-443-15684-7.00004-xopenalex-snapshot
Principles of nature on human sensing capabilities
inferred← citeshttps://doi.org/10.1016/b978-0-443-24705-7.00011-9openalex-snapshot
Piezo channels in peripheral trigeminal nociception
inferred← citeshttps://doi.org/10.1016/b978-0-443-34172-4.00002-1openalex-snapshot
Non-TRP ion channels involved in itch
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2015.11.006openalex-snapshot
Ion Channels in the Eye
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2025.03.008openalex-snapshot
Development and regeneration of Merkel cells
inferred← citeshttps://doi.org/10.1016/bs.ctm.2016.09.001openalex-snapshot
Origin of the Force
inferred← citeshttps://doi.org/10.1016/bs.ctm.2016.10.001openalex-snapshot
The Structural Basis for Sensing by the Piezo1 Protein
inferred← citeshttps://doi.org/10.1016/bs.ctm.2016.10.002openalex-snapshot
Regulation of Piezo Channels by Cellular Signaling Pathways
inferred← citeshttps://doi.org/10.1016/bs.ctm.2016.10.003openalex-snapshot
Role of Piezo Channels in Joint Health and Injury
inferred← citeshttps://doi.org/10.1016/bs.ctm.2016.11.002openalex-snapshot
Piezo2 in Cutaneous and Proprioceptive Mechanotransduction in Vertebrates
inferred← citeshttps://doi.org/10.1016/bs.ctm.2016.11.003openalex-snapshot
Mechanosensitive Piezo Channels in the Gastrointestinal Tract
inferred← citeshttps://doi.org/10.1016/bs.ctm.2016.11.007openalex-snapshot
A Tour de Force
inferred← citeshttps://doi.org/10.1016/bs.ctm.2017.01.001openalex-snapshot
Genetic Diseases of PIEZO1 and PIEZO2 Dysfunction
inferred← citeshttps://doi.org/10.1016/bs.ctm.2020.01.008openalex-snapshot
Ion channels and myogenic activity in retinal arterioles
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2014.11.011openalex-snapshot
Contribution of Mechanosensitive Ion Channels to Somatosensation
inferred← citeshttps://doi.org/10.1016/j.aanat.2019.151456openalex-snapshot
The sensory innervation of the human nipple
inferred← citeshttps://doi.org/10.1016/j.aanat.2021.151813openalex-snapshot
Human digital merkel cells display pannexin1 immunoreactivity
inferred← citeshttps://doi.org/10.1016/j.aanat.2022.151953openalex-snapshot
The acquisition of mechanoreceptive competence by human digital Merkel cells and sensory corpuscles during development: An immunohistochemical study of PIEZO2
inferred← citeshttps://doi.org/10.1016/j.aanat.2023.152200openalex-snapshot
Immunohistochemical detection of PIEZO1 and PIEZO2 in human digital Meissner´s corpuscles
inferred← citeshttps://doi.org/10.1016/j.ajhg.2016.09.019openalex-snapshot
Biallelic Loss of Proprioception-Related PIEZO2 Causes Muscular Atrophy with Perinatal Respiratory Distress, Arthrogryposis, and Scoliosis
inferred← citeshttps://doi.org/10.1016/j.alit.2025.01.004openalex-snapshot
The gut–organ axis: Clinical aspects and immune mechanisms
inferred← citeshttps://doi.org/10.1016/j.apsb.2023.05.010openalex-snapshot
Potentiation of PIEZO2 mechanically-activated currents in sensory neurons mediates vincristine-induced mechanical hypersensitivity
inferred← citeshttps://doi.org/10.1016/j.archoralbio.2024.105963openalex-snapshot
The role of the Piezo1 channel in osteoblasts under cyclic stretching: A study on osteogenic and osteoclast factors
inferred← citeshttps://doi.org/10.1016/j.arr.2023.101931openalex-snapshot
Restoration of metal homeostasis: a potential strategy against neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.bbamem.2015.04.012openalex-snapshot
Lipid–protein interactions: Lessons learned from stress
inferred← citeshttps://doi.org/10.1016/j.bbr.2021.113594openalex-snapshot
Inhibition of Piezo1/Ca2+/calpain signaling in the rat basal forebrain reverses sleep deprivation-induced fear memory impairments
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.10.043openalex-snapshot
Gene expression profiling of osteoblasts subjected to dexamethasone-induced apoptosis with/without GSK3β-shRNA
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152422openalex-snapshot
PIEZO2 channels: mediators of mechanotransduction and cell-cell communication as revealed by localized mechanical stimulation
inferred← citeshttps://doi.org/10.1016/j.biopsych.2024.11.003openalex-snapshot
Trauma and Sensory Systems: Biological Mechanisms Involving the Skin and the 17q21 Gene Cluster
inferred← citeshttps://doi.org/10.1016/j.bpj.2016.12.009openalex-snapshot
Signatures of Mechanosensitive Gating
inferred← citeshttps://doi.org/10.1016/j.bpj.2021.11.019openalex-snapshot
Endocytosis and exocytosis protect cells against severe membrane tension variations
inferred← citeshttps://doi.org/10.1016/j.bpj.2025.06.005openalex-snapshot
Propofol inhibits Piezo mechanosensitive channels
inferred← citeshttps://doi.org/10.1016/j.bpj.2025.06.014openalex-snapshot
Mechanical memory of excitable cells induced by mechanosensitive channel inactivation
inferred← citeshttps://doi.org/10.1016/j.bpj.2025.10.042openalex-snapshot
Mechanically gated currents in mouse sensory neurons lacking PIEZO2
inferred← citeshttps://doi.org/10.1016/j.brainres.2018.02.039openalex-snapshot
The touchy business of gastrointestinal (GI) mechanosensitivity
inferred← citeshttps://doi.org/10.1016/j.ceb.2023.102219openalex-snapshot
Mechanotransduction: Forcing a change in metabolism
inferred← citeshttps://doi.org/10.1016/j.ceca.2026.103181openalex-snapshot
Piezo1-mitochondrial calcium coupling in mechanotransduction, mitochondrial stress, and cell fate
inferred← citeshttps://doi.org/10.1016/j.cell.2015.11.060openalex-snapshot
Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking
inferred← citeshttps://doi.org/10.1016/j.cell.2018.02.047openalex-snapshot
Common PIEZO1 Allele in African Populations Causes RBC Dehydration and Attenuates Plasmodium Infection
inferred← citeshttps://doi.org/10.1016/j.cell.2018.03.076openalex-snapshot
GPR68 Senses Flow and Is Essential for Vascular Physiology
inferred← citeshttps://doi.org/10.1016/j.cell.2019.08.049openalex-snapshot
Mammalian Mechanoelectrical Transduction: Structure and Function of Force-Gated Ion Channels
inferred← citeshttps://doi.org/10.1016/j.cell.2021.09.023openalex-snapshot
Mechanoreceptor synapses in the brainstem shape the central representation of touch
inferred← citeshttps://doi.org/10.1016/j.cell.2022.10.012openalex-snapshot
Mechanoreceptor signal convergence and transformation in the dorsal horn flexibly shape a diversity of outputs to the brain
inferred← citeshttps://doi.org/10.1016/j.cell.2023.07.006openalex-snapshot
PIEZO2 in somatosensory neurons controls gastrointestinal transit
inferred← citeshttps://doi.org/10.1016/j.cell.2024.02.006openalex-snapshot
A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes
inferred← citeshttps://doi.org/10.1016/j.cell.2024.04.010openalex-snapshot
Perivascular neurons instruct 3D vascular lattice formation via neurovascular contact
inferred← citeshttps://doi.org/10.1016/j.cell.2025.10.041openalex-snapshot
Properties and functions of transcriptionally distinct enteric neurons
inferred← citeshttps://doi.org/10.1016/j.cellsig.2020.109877openalex-snapshot
The functions of mechanosensitive ion channels in tooth and bone tissues
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.10.034openalex-snapshot
Touch Receptors Undergo Rapid Remodeling in Healthy Skin
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.05.079openalex-snapshot
Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.10.120openalex-snapshot
Inactivation of Mechanically Activated Piezo1 Ion Channels Is Determined by the C-Terminal Extracellular Domain and the Inner Pore Helix
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.11.035openalex-snapshot
Cell-Type-Specific Splicing of Piezo2 Regulates Mechanotransduction
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.01.056openalex-snapshot
Mechanically Activated Piezo Channels Mediate Touch and Suppress Acute Mechanical Pain Response in Mice
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.07.017openalex-snapshot
Development of a Mouse Pain Scale Using Sub-second Behavioral Mapping and Statistical Modeling
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.08.075openalex-snapshot
Biophysical Principles of Ion-Channel-Mediated Mechanosensory Transduction
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.10.040openalex-snapshot
Arterial Baroreceptors Sense Blood Pressure through Decorated Aortic Claws
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.12.040openalex-snapshot
Inactivation Kinetics and Mechanical Gating of Piezo1 Ion Channels Depend on Subdomains within the Cap
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.107912openalex-snapshot
Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.110342openalex-snapshot
Tethering Piezo channels to the actin cytoskeleton for mechanogating via the cadherin-β-catenin mechanotransduction complex
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.112283openalex-snapshot
MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114014openalex-snapshot
TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114230openalex-snapshot
Plp1-expresssing perineuronal DRG cells facilitate colonic and somatic chronic mechanical pain involving Piezo2 upregulation in DRG neurons
inferred← citeshttps://doi.org/10.1016/j.celrep.2024.114860openalex-snapshot
Comprehensive mapping of sensory and sympathetic innervation of the developing kidney
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.116175openalex-snapshot
The bidirectional interplay between RNA processing and mechanotransduction
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.116651openalex-snapshot
Membrane dome-based regulation mechanism of the mechanosensitive PIEZO channel
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.116693openalex-snapshot
The production of the chemokine CCL2 by corneal sensory neurons initiates anti-viral immunity at the cornea and trigeminal ganglion
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.116878openalex-snapshot
Structures of invertebrate PEZO-1 isoforms with a compact architecture and a dispensable pore-distal N-terminal blade
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.117521openalex-snapshot
Piezo2 tension sensitivity and its modulation by alternative splicing
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.118160openalex-snapshot
Proprioceptive sensory-driven mechanisms shape Clarke’s column development
inferred← citeshttps://doi.org/10.1016/j.cmet.2024.12.016openalex-snapshot
Piezo2 in sensory neurons regulates systemic and adipose tissue metabolism
inferred← citeshttps://doi.org/10.1016/j.cmet.2025.02.004openalex-snapshot
A key role of PIEZO2 mechanosensitive ion channel in adipose sensory innervation
inferred← citeshttps://doi.org/10.1016/j.conb.2015.05.003openalex-snapshot
Mammalian touch catches up
inferred← citeshttps://doi.org/10.1016/j.conb.2016.07.007openalex-snapshot
Spinal sensory circuits in motion
inferred← citeshttps://doi.org/10.1016/j.conb.2022.102542openalex-snapshot
Molecular determinants of mechanosensation in the muscle spindle
inferred← citeshttps://doi.org/10.1016/j.conb.2022.102548openalex-snapshot
Tactile sensation in birds: Physiological insights from avian mechanoreceptors
inferred← citeshttps://doi.org/10.1016/j.conb.2026.103226openalex-snapshot
Peripheral mechanisms of tactile sensation in fish
inferred← citeshttps://doi.org/10.1016/j.cophys.2020.11.007openalex-snapshot
Mechanotransduction channels in proprioceptive sensory nerve terminals: still an open question?
inferred← citeshttps://doi.org/10.1016/j.cophys.2021.01.004openalex-snapshot
More than movement: the proprioceptive system as a new regulator of musculoskeletal biology
inferred← citeshttps://doi.org/10.1016/j.cub.2014.05.011openalex-snapshot
Sensory Biology: It Takes Piezo2 to Tango
inferred← citeshttps://doi.org/10.1016/j.cub.2019.12.068openalex-snapshot
The Cellular and Mechanical Basis for Response Characteristics of Identified Primary Afferents in the Rat Vibrissal System
inferred← citeshttps://doi.org/10.1016/j.cub.2021.06.002openalex-snapshot
Drosophila females receive male substrate-borne signals through specific leg neurons during courtship
inferred← citeshttps://doi.org/10.1016/j.cub.2025.08.035openalex-snapshot
Functional evidence for early origin of tactile acuity in the vertebrate somatosensory system
inferred← citeshttps://doi.org/10.1016/j.devcel.2015.03.010openalex-snapshot
Sarcomeres Pattern Proprioceptive Sensory Dendritic Endings through UNC-52/Perlecan in C. elegans
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.09.024openalex-snapshot
Less Is More: Rare Pulmonary Neuroendocrine Cells Function as Critical Sensors in Lung
inferred← citeshttps://doi.org/10.1016/j.ebiom.2025.105808openalex-snapshot
Mechanotransduction as a therapeutic target for brain tumours
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116502openalex-snapshot
Piezo1 and its inhibitors: Overview and perspectives
inferred← citeshttps://doi.org/10.1016/j.eng.2021.02.014openalex-snapshot
Ionic Elastomers for Electric Actuators and Sensors
inferred← citeshttps://doi.org/10.1016/j.exer.2023.109675openalex-snapshot
Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles
inferred← citeshttps://doi.org/10.1016/j.exer.2023.109719openalex-snapshot
Piezo1 channel causes lens sclerosis via transglutaminase 2 activation
inferred← citeshttps://doi.org/10.1016/j.exer.2026.111208openalex-snapshot
Verification of the expression of Piezo1 and Piezo2 ion channels in the mouse lens during the embryonic, postnatal and adult growth
inferred← citeshttps://doi.org/10.1016/j.expneurol.2023.114552openalex-snapshot
Expression pattern analysis and characterization of the hereditary sensory and autonomic neuropathy 2 A (HSAN2A) gene with no lysine kinase (WNK1) in human dorsal root ganglion
inferred← citeshttps://doi.org/10.1016/j.ibneur.2022.09.008openalex-snapshot
Reducing Merkel cell activity in the whisker follicle disrupts cortical encoding of whisker movement amplitude and velocity
inferred← citeshttps://doi.org/10.1016/j.ijhcs.2022.102881openalex-snapshot
Interpersonal Haptic Communication: Review and Directions for the Future
inferred← citeshttps://doi.org/10.1016/j.immuni.2025.11.011openalex-snapshot
The history and promise of Treg cells
inferred← citeshttps://doi.org/10.1016/j.isci.2021.102042openalex-snapshot
The role of Piezo1 in conventional aqueous humor outflow dynamics
inferred← citeshttps://doi.org/10.1016/j.isci.2021.102721openalex-snapshot
Physical contact in parent-infant relationship and its effect on fostering a feeling of safety
inferred← citeshttps://doi.org/10.1016/j.isci.2024.109069openalex-snapshot
Mapping the developmental potential of mouse inner ear organoids at single-cell resolution
inferred← citeshttps://doi.org/10.1016/j.isci.2024.109396openalex-snapshot
A novel Nav1.8-FLPo driver mouse for intersectional genetics to uncover the functional significance of primary sensory neuron diversity
inferred← citeshttps://doi.org/10.1016/j.jbc.2023.104782openalex-snapshot
PKA mediates modality-specific modulation of the mechanically gated ion channel PIEZO2
inferred← citeshttps://doi.org/10.1016/j.jid.2017.11.004openalex-snapshot
Merkel Cells Sense Cooling with TRPM8 Channels
inferred← citeshttps://doi.org/10.1016/j.jid.2018.02.010openalex-snapshot
Attenuated Activation of Homeostatic Glucocorticoid in Keratinocytes Induces Alloknesis via Aberrant Artemin Production
inferred← citeshttps://doi.org/10.1016/j.jid.2024.03.034openalex-snapshot
Human Merkel Cells as the Initiator of Mechanotransduction in the Skin: Linking the Animal Model to Humans
inferred← citeshttps://doi.org/10.1016/j.jneumeth.2019.03.010openalex-snapshot
Development of a traumatic cervical dislocation spinal cord injury model with residual compression in the rat
inferred← citeshttps://doi.org/10.1016/j.job.2025.100722openalex-snapshot
Choline acetyltransferase as a marker for Merkel cells in mucosal and skin tissues
inferred← citeshttps://doi.org/10.1016/j.joen.2018.02.020openalex-snapshot
Activation of Mechanosensitive Transient Receptor Potential/Piezo Channels in Odontoblasts Generates Action Potentials in Cocultured Isolectin B 4 –negative Medium-sized Trigeminal Ganglion Neurons
inferred← citeshttps://doi.org/10.1016/j.joen.2022.07.012openalex-snapshot
Expression of Piezo2 in the Dental Pulp, Sensory Root, and Trigeminal Ganglion and Its Coexpression with Vesicular Glutamate Transporters
inferred← citeshttps://doi.org/10.1016/j.jpain.2015.08.014openalex-snapshot
Bedding Material Affects Mechanical Thresholds, Heat Thresholds, and Texture Preference
inferred← citeshttps://doi.org/10.1016/j.jpain.2020.11.004openalex-snapshot
Involvement of TACAN, a Mechanotransducing Ion Channel, in Inflammatory But Not Neuropathic Hyperalgesia in the Rat
inferred← citeshttps://doi.org/10.1016/j.jpain.2023.07.023openalex-snapshot
Topical Oxaliplatin Produces Gain- and Loss-of-Function in Multiple Classes of Sensory Afferents
inferred← citeshttps://doi.org/10.1016/j.jpha.2026.101753openalex-snapshot
Mechanosensitive ion channels: Shedding light on their functions and mechanisms in digestive system diseases
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