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The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/hep.23506openalex-snapshot
Generation of Functional Hepatocytes From Human Embryonic Stem Cells Under Chemically Defined Conditions That Recapitulate Liver Development
inferredcites →https://doi.org/10.1002/stem.199openalex-snapshot
Signaling Pathways Controlling Pluripotency and Early Cell Fate Decisions of Human Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1002/stem.666openalex-snapshot
Activin/Nodal Signaling Controls Divergent Transcriptional Networks in Human Embryonic Stem Cells and in Endoderm Progenitors
inferredcites →https://doi.org/10.1006/meth.2001.1262openalex-snapshot
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
inferredcites →https://doi.org/10.1007/978-1-60761-962-8_3openalex-snapshot
Serum-Free and Feeder-Free Culture Conditions for Human Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/0003-2697(91)90500-sopenalex-snapshot
A comparison of apparent mRNA half-life using kinetic labeling techniques vs decay following administration of transcriptional inhibitors
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A Lentiviral RNAi Library for Human and Mouse Genes Applied to an Arrayed Viral High-Content Screen
inferredcites →https://doi.org/10.1016/j.cell.2012.05.003openalex-snapshot
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
inferredcites →https://doi.org/10.1016/j.cell.2015.04.021openalex-snapshot
An Adenine Code for DNA: A Second Life for N6-Methyladenine
inferredcites →https://doi.org/10.1016/j.cell.2015.10.012openalex-snapshot
5′ UTR m6A Promotes Cap-Independent Translation
inferredcites →https://doi.org/10.1016/j.celrep.2014.05.048openalex-snapshot
Perturbation of m6A Writers Reveals Two Distinct Classes of mRNA Methylation at Internal and 5′ Sites
inferredcites →https://doi.org/10.1016/j.devcel.2009.02.012openalex-snapshot
TGF-β Superfamily Signaling in Embryonic Development and Homeostasis
inferredcites →https://doi.org/10.1016/j.molcel.2010.05.004openalex-snapshot
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
inferredcites →https://doi.org/10.1016/j.semcdb.2014.01.009openalex-snapshot
TGF-β signaling to chromatin: How Smads regulate transcription during self-renewal and differentiation
inferredcites →https://doi.org/10.1016/j.stem.2012.11.001openalex-snapshot
The Harmonies Played by TGF-β in Stem Cell Biology
inferredcites →https://doi.org/10.1016/j.stem.2014.06.006openalex-snapshot
NANOG and CDX2 Pattern Distinct Subtypes of Human Mesoderm during Exit from Pluripotency
inferredcites →https://doi.org/10.1016/j.stem.2014.09.019openalex-snapshot
m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.stemcr.2017.02.016openalex-snapshot
Inducible and Deterministic Forward Programming of Human Pluripotent Stem Cells into Neurons, Skeletal Myocytes, and Oligodendrocytes
inferredcites →https://doi.org/10.1016/j.ydbio.2004.08.031openalex-snapshot
Nodal inhibits differentiation of human embryonic stem cells along the neuroectodermal default pathway
inferredcites →https://doi.org/10.1016/j.ydbio.2007.10.003openalex-snapshot
Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm
inferredcites →https://doi.org/10.1016/j.ymeth.2010.12.016openalex-snapshot
Extracting gene function from protein–protein interactions using Quantitative BAC InteraCtomics (QUBIC)
inferredcites →https://doi.org/10.1021/pr5009515openalex-snapshot
A Quantitative Proteomics Tool To Identify DNA–Protein Interactions in Primary Cells or Blood
inferredcites →https://doi.org/10.1038/36285openalex-snapshot
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
inferredcites →https://doi.org/10.1038/nature10424openalex-snapshot
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
inferredcites →https://doi.org/10.1038/nature11112openalex-snapshot
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
inferredcites →https://doi.org/10.1038/nature12730openalex-snapshot
N6-methyladenosine-dependent regulation of messenger RNA stability
inferredcites →https://doi.org/10.1038/nature24678openalex-snapshot
Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control
inferredcites →https://doi.org/10.1038/nbt.1511openalex-snapshot
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
inferredcites →https://doi.org/10.1038/nbt.1621openalex-snapshot
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
inferredcites →https://doi.org/10.1038/nbt1163openalex-snapshot
Efficient differentiation of human embryonic stem cells to definitive endoderm
inferredcites →https://doi.org/10.1038/nm.4416openalex-snapshot
The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells
inferredcites →https://doi.org/10.1038/nmeth.1923openalex-snapshot
Fast gapped-read alignment with Bowtie 2
inferredcites →https://doi.org/10.1038/nmeth.4110openalex-snapshot
Epitranscriptome sequencing technologies: decoding RNA modifications
inferredcites →https://doi.org/10.1038/nprot.2007.261openalex-snapshot
Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips
inferredcites →https://doi.org/10.1038/nprot.2009.21openalex-snapshot
Multiplex peptide stable isotope dimethyl labeling for quantitative proteomics
inferredcites →https://doi.org/10.1038/nprot.2012.148openalex-snapshot
Transcriptome-wide mapping of N6-methyladenosine by m6A-seq based on immunocapturing and massively parallel sequencing
inferredcites →https://doi.org/10.1038/nrc3603openalex-snapshot
The roles of TGFβ in the tumour microenvironment
inferredcites →https://doi.org/10.1083/jcb.200911091openalex-snapshot
Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactions
inferredcites →https://doi.org/10.1093/bioinformatics/btp352openalex-snapshot
The Sequence Alignment/Map format and SAMtools
inferredcites →https://doi.org/10.1093/bioinformatics/btr020openalex-snapshot
Dalliance: interactive genome viewing on the web
inferredcites →https://doi.org/10.1093/bioinformatics/btr261openalex-snapshot
DREME: motif discovery in transcription factor ChIP-seq data
inferredcites →https://doi.org/10.1093/bioinformatics/bts356openalex-snapshot
RSeQC: quality control of RNA-seq experiments
inferredcites →https://doi.org/10.1093/bioinformatics/btt171openalex-snapshot
Exome-based analysis for RNA epigenome sequencing data
inferredcites →https://doi.org/10.1093/bioinformatics/btt343openalex-snapshot
GAT: a simulation framework for testing the association of genomic intervals
inferredcites →https://doi.org/10.1093/bioinformatics/btt656openalex-snapshot
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
inferredcites →https://doi.org/10.1093/bioinformatics/btu170openalex-snapshot
Trimmomatic: a flexible trimmer for Illumina sequence data
inferredcites →https://doi.org/10.1093/bioinformatics/btw724openalex-snapshot
fCCAC: functional canonical correlation analysis to evaluate covariance between nucleic acid sequencing datasets
inferredcites →https://doi.org/10.1093/nar/gkx120openalex-snapshot
RCAS: an RNA centric annotation system for transcriptome-wide regions of interest
inferredcites →https://doi.org/10.1093/nar/gkx778openalex-snapshot
N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing
inferredcites →https://doi.org/10.1101/gad.255984.114openalex-snapshot
Activin/Nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark
inferredcites →https://doi.org/10.1101/gad.269415.115openalex-snapshot
A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation
inferredcites →https://doi.org/10.1101/gad.301036.117openalex-snapshot
m 6 A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover
inferredcites →https://doi.org/10.1101/gad.607311openalex-snapshot
Pluripotency factors regulate definitive endoderm specification through eomesodermin
inferredcites →https://doi.org/10.1101/gr.1239303openalex-snapshot
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
inferredcites →https://doi.org/10.1109/tcbb.2015.2403355openalex-snapshot
MeTDiff: A Novel Differential RNA Methylation Analysis for MeRIP-Seq Data
inferredcites →https://doi.org/10.1126/science.1261417openalex-snapshot
m 6 A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation
inferredcites →https://doi.org/10.1186/1471-2105-14-128openalex-snapshot
Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
inferredcites →https://doi.org/10.1186/gb-2008-9-9-r137openalex-snapshot
Model-based Analysis of ChIP-Seq (MACS)
inferredcites →https://doi.org/10.1186/gb-2012-13-10-175openalex-snapshot
The birth of the Epitranscriptome: deciphering the function of RNA modifications
inferredcites →https://doi.org/10.1186/gb-2013-14-4-r36openalex-snapshot
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
inferredcites →https://doi.org/10.1186/s13059-014-0550-8openalex-snapshot
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
inferredcites →https://doi.org/10.1186/s13059-016-0881-8openalex-snapshot
A survey of best practices for RNA-seq data analysis
inferredcites →https://doi.org/10.1242/dev.01044openalex-snapshot
Development of definitive endoderm from embryonic stem cells in culture
inferredcites →https://doi.org/10.1242/dev.01706openalex-snapshot
TGFβ/activin/nodal signaling is necessary for the maintenance of pluripotency in human embryonic stem cells
inferredcites →https://doi.org/10.1242/dev.033951openalex-snapshot
Activin/Nodal signalling maintains pluripotency by controlling Nanog expression
inferredcites →https://doi.org/10.1242/dev.138081openalex-snapshot
Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs
inferredcites →https://doi.org/10.1242/jcs.02553openalex-snapshot
Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells
inferredcites →https://doi.org/10.1371/journal.pone.0006082openalex-snapshot
Early Cell Fate Decisions of Human Embryonic Stem Cells and Mouse Epiblast Stem Cells Are Controlled by the Same Signalling Pathways
inferredcites →https://doi.org/10.2202/1544-6115.1027openalex-snapshot
Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/advs.202404904openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/advs.202507549openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/asia.202200367openalex-snapshot
Mechanisms and Strategies for Determining m6A RNA Modification Sites by Natural and Engineered m6A Effector Proteins
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RNA N6‐methyladenosine modification in the lethal teamwork of cancer stem cells and the tumor immune microenvironment: Current landscape and therapeutic potential
inferred← citeshttps://doi.org/10.1002/ctm2.906openalex-snapshot
ZNF677 suppresses renal cell carcinoma progression through N6‐methyladenosine and transcriptional repression of CDKN3
inferred← citeshttps://doi.org/10.1002/kjm2.12266openalex-snapshot
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Bioinformatic Analysis of m6A Regulator-Mediated RNA Methylation Modification Patterns and Immune Microenvironment Characterization in Endometriosis
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METTL14 Promotes the Osteogenic Differentiation of Human Bone Marrow Stromal Cells via m6A-Dependent Stabilization of USP7 mRNA
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RNA methylation in mammalian development and cancer
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Deciphering the Epitranscriptomic Signatures in Cell Fate Determination and Development
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METTL3–METTL14 complex induces necroptosis and inflammation of vascular smooth muscle cells via promoting N6 methyladenosine mRNA methylation of receptor-interacting protein 3 in abdominal aortic aneurysms
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MicroRNA Biogenesis Modulates mRNA N6-methyladenosine Methylation in Arabidopsis
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Mechanisms and clinical significance of TGF-β in hepatocellular cancer progression
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Insights into the epitranscriptomic role of N6-methyladenosine on aging skeletal muscle
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METTL3-STAT5B interaction facilitates the co-transcriptional m6A modification of mRNA to promote breast tumorigenesis
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m6A Modification in Coding and Non-coding RNAs: Roles and Therapeutic Implications in Cancer
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METTL3-mediated m6A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis
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A cancer-associated METTL14 mutation induces aberrant m6A modification, affecting tumor growth
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HDAC2-mediated recruitment of METTL3 to chromatin regulates human embryonic stem cell differentiation
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Modifying the antiviral innate immune response by selective writing, erasing, and reading of m6A on viral and cellular RNA
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RNA m6A modification: a key regulator in normal and malignant processes
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RNA N6-methyladenosine modification promotes auxin biosynthesis required for male meiosis in rice
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Fatty acid synthesis and oxidation regulate human endoderm differentiation by mediating SMAD3 nuclear localization via acetylation
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Nodal/Smad2 signaling sustains developmental pausing by repressing Pparg-mediated lipid metabolism
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Stage-specific requirement for m6A RNA methylation during cardiac differentiation of pluripotent stem cells
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m6A RNA methylation and beyond – The epigenetic machinery and potential treatment options
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The regulatory role of m6A modification in the maintenance and differentiation of embryonic stem cells
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The role of N6-methyladenine methylation in kidney diseases: Mechanisms and therapeutic potential
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The crosstalk between RNA m6A epitranscriptome and TGFβ signaling pathway contributes to the arrest of cell cycle
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Structural Insights into N 6 -Methyladenosine (m 6 A) Modification in the Transcriptome
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Specific Regulation of m6A by SRSF7 Promotes the Progression of Glioblastoma
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m6A Profile Dynamics Indicates Regulation of Oyster Development by m6A-RNA Epitranscriptomes
inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e21307openalex-snapshot
Global m6A methylation and gene expression patterns in human microglial HMC3 cells infected with HIV-1
inferred← citeshttps://doi.org/10.1016/j.immuni.2020.05.003openalex-snapshot
m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development
inferred← citeshttps://doi.org/10.1016/j.jare.2025.06.030openalex-snapshot
Targeting intracellular mRNA m6A-modifiers in advancing immunotherapeutics
inferred← citeshttps://doi.org/10.1016/j.jbc.2021.101294openalex-snapshot
Metabolic turnover and dynamics of modified ribonucleosides by 13C labeling
inferred← citeshttps://doi.org/10.1016/j.jbc.2022.102715openalex-snapshot
N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis
inferred← citeshttps://doi.org/10.1016/j.jbc.2024.107256openalex-snapshot
Receptor-activated transcription factors and beyond: multiple modes of Smad2/3-dependent transmission of TGF-β signaling
inferred← citeshttps://doi.org/10.1016/j.jbc.2024.107598openalex-snapshot
N6-methyladenosine triggers renal fibrosis via enhancing translation and stability of ZEB2 mRNA
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.06.012openalex-snapshot
Inflammation Writes the Fibrogenic Code
inferred← citeshttps://doi.org/10.1016/j.jep.2023.116433openalex-snapshot
Chinese Ecliptae herba (Eclipta prostrata (L.) L.) extract and its component wedelolactone enhances osteoblastogenesis of bone marrow mesenchymal stem cells via targeting METTL3-mediated m6A RNA methylation
inferred← citeshttps://doi.org/10.1016/j.jid.2026.01.019openalex-snapshot
FTO/SOCS6–m6A axis epigenetic modification links obesity to atopic dermatitis by regulating keratinocyte function
inferred← citeshttps://doi.org/10.1016/j.lfs.2024.123122openalex-snapshot
The effect of m6A methyltransferase METTL3 mediated TMEM30A regulation on tumor energy metabolism and cisplatin anti-tumor activity in oral squamous cell carcinoma
inferred← citeshttps://doi.org/10.1016/j.meegid.2022.105389openalex-snapshot
The risk of COVID-19 can be predicted by a nomogram based on m6A-related genes
inferred← citeshttps://doi.org/10.1016/j.molcel.2019.04.025openalex-snapshot
Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers
inferred← citeshttps://doi.org/10.1016/j.molcel.2020.10.026openalex-snapshot
Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation
inferred← citeshttps://doi.org/10.1016/j.molcel.2022.04.010openalex-snapshot
The Mettl3 epitranscriptomic writer amplifies p53 stress responses
inferred← citeshttps://doi.org/10.1016/j.molcel.2023.05.010openalex-snapshot
RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity
inferred← citeshttps://doi.org/10.1016/j.molcel.2024.07.017openalex-snapshot
Nuclear retention coupled with sequential polyadenylation dictates post-transcriptional m6A modification in the nucleus
inferred← citeshttps://doi.org/10.1016/j.molcel.2025.01.014openalex-snapshot
Single-molecule m6A detection empowered by endogenous labeling unveils complexities across RNA isoforms
inferred← citeshttps://doi.org/10.1016/j.molmet.2019.06.003openalex-snapshot
“Omics” and “epi-omics” underlying the β-cell adaptation to insulin resistance
inferred← citeshttps://doi.org/10.1016/j.omtn.2020.10.031openalex-snapshot
ALKBH5 Inhibited Cell Proliferation and Sensitized Bladder Cancer Cells to Cisplatin by m6A-CK2α-Mediated Glycolysis
inferred← citeshttps://doi.org/10.1016/j.omtn.2021.05.019openalex-snapshot
ALKBH5-mediated m6A mRNA methylation governs human embryonic stem cell cardiac commitment
inferred← citeshttps://doi.org/10.1016/j.omtn.2024.102164openalex-snapshot
TGF-β1-triggered BMI1 and SMAD2 cooperatively regulate miR-191 to modulate bone formation
inferred← citeshttps://doi.org/10.1016/j.pbi.2021.102047openalex-snapshot
N6-methyladenosine modification underlies messenger RNA metabolism and plant development
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2024.12.003openalex-snapshot
Research progress on N6-Methyladenosine modification in angiogenesis, vasculogenic mimicry, and therapeutic implications in breast cancer
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2020.107666openalex-snapshot
TGFβ-Directed Therapeutics: 2020
inferred← citeshttps://doi.org/10.1016/j.plantsci.2024.112228openalex-snapshot
The knockout of SlMTC impacts tomato seed size and reduces resistance to salt stress in tomato
inferred← citeshttps://doi.org/10.1016/j.sciaf.2022.e01347openalex-snapshot
Recent developments in the significant effect of mRNA modification (M6A) in glioblastoma and esophageal cancer
inferred← citeshttps://doi.org/10.1016/j.stem.2019.08.018openalex-snapshot
The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis
inferred← citeshttps://doi.org/10.1016/j.stem.2021.04.001openalex-snapshot
Principles of signaling pathway modulation for enhancing human naive pluripotency induction
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2021.08.027openalex-snapshot
SMAD2 regulates testicular development and testosterone synthesis in Hu sheep
inferred← citeshttps://doi.org/10.1016/j.tice.2020.101406openalex-snapshot
The effective role of sodium copper chlorophyllin on the dysfunction of bone marrow mesenchymal stem cells in multiple myeloma via regulating TGF-β1
inferred← citeshttps://doi.org/10.1016/j.tig.2019.10.011openalex-snapshot
The Biogenesis and Precise Control of RNA m6A Methylation
inferred← citeshttps://doi.org/10.1016/j.tranon.2024.102035openalex-snapshot
ETV4 promotes the progression of cholangiocarcinoma by regulating glycolysis via the TGF-β signaling
inferred← citeshttps://doi.org/10.1016/j.treopn.2026.07.017openalex-snapshot
Extending the reach of transcription factors to mRNA stability
inferred← citeshttps://doi.org/10.1016/j.ydbio.2022.04.005openalex-snapshot
The role of cnidarian developmental biology in unraveling axis formation and Wnt signaling
inferred← citeshttps://doi.org/10.1016/j.yexcr.2021.112524openalex-snapshot
FTO regulates myoblast proliferation by controlling CCND1 expression in an m6A-YTHDF2-dependent manner
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2021.05.006openalex-snapshot
Relevance of N6-methyladenosine regulators for transcriptome: Implications for development and the cardiovascular system
inferred← citeshttps://doi.org/10.1016/j.ymthe.2024.05.035openalex-snapshot
Decoding the specificity of m6A RNA methylation and its implication in cancer therapy
inferred← citeshttps://doi.org/10.1038/s12276-022-00824-xopenalex-snapshot
New insights into the epitranscriptomic control of pluripotent stem cell fate
inferred← citeshttps://doi.org/10.1038/s12276-023-01059-0openalex-snapshot
ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression
inferred← citeshttps://doi.org/10.1038/s41380-023-02028-9openalex-snapshot
Epigenetic and epitranscriptomic regulation of axon regeneration
inferred← citeshttps://doi.org/10.1038/s41413-021-00163-zopenalex-snapshot
Spatially defined single-cell transcriptional profiling characterizes diverse chondrocyte subtypes and nucleus pulposus progenitors in human intervertebral discs
inferred← citeshttps://doi.org/10.1038/s41417-025-00993-7openalex-snapshot
m6A epitranscriptomic regulation of KRAS by METTL3 promotes EMT and stromal remodeling through TGF-β/SMAD signaling in cervical cancer
inferred← citeshttps://doi.org/10.1038/s41419-020-03143-zopenalex-snapshot
The role of m6A modification in physiology and disease
inferred← citeshttps://doi.org/10.1038/s41419-020-2284-8openalex-snapshot
Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy
inferred← citeshttps://doi.org/10.1038/s41419-023-05736-wopenalex-snapshot
Aberrant RNA m6A modification in gastrointestinal malignancies: versatile regulators of cancer hallmarks and novel therapeutic opportunities
inferred← citeshttps://doi.org/10.1038/s41419-024-06800-9openalex-snapshot
TGF-β1 facilitates gallbladder carcinoma metastasis by regulating FOXA1 translation efficiency through m6A modification
inferred← citeshttps://doi.org/10.1038/s41420-023-01485-zopenalex-snapshot
Role of N6-methyladenosine RNA modification in gastric cancer
inferred← citeshttps://doi.org/10.1038/s41422-018-0037-3openalex-snapshot
m6A deposition: a boost from TGFβ
inferred← citeshttps://doi.org/10.1038/s41422-018-0072-0openalex-snapshot
Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion
inferred← citeshttps://doi.org/10.1038/s41422-020-00397-2openalex-snapshot
Oncogenic AURKA-enhanced N6-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells
inferred← citeshttps://doi.org/10.1038/s41467-019-09865-9openalex-snapshot
RETRACTED ARTICLE: RNA m6A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail
inferred← citeshttps://doi.org/10.1038/s41467-019-09903-6openalex-snapshot
Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation
inferred← citeshttps://doi.org/10.1038/s41467-020-14665-7openalex-snapshot
A computational platform for high-throughput analysis of RNA sequences and modifications by mass spectrometry
inferred← citeshttps://doi.org/10.1038/s41467-021-21537-1openalex-snapshot
A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
inferred← citeshttps://doi.org/10.1038/s41467-021-24035-6openalex-snapshot
Arginine methylation of METTL14 promotes RNA N6-methyladenosine modification and endoderm differentiation of mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1038/s41467-021-27848-7openalex-snapshot
The m6A methyltransferase METTL3 regulates muscle maintenance and growth in mice
inferred← citeshttps://doi.org/10.1038/s41467-022-28106-0openalex-snapshot
Parallel functional assessment of m6A sites in human endodermal differentiation with base editor screens
inferred← citeshttps://doi.org/10.1038/s41467-022-35643-1openalex-snapshot
Exon junction complex shapes the m6A epitranscriptome
inferred← citeshttps://doi.org/10.1038/s41467-024-46711-zopenalex-snapshot
Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice
inferred← citeshttps://doi.org/10.1038/s41467-024-55694-wopenalex-snapshot
Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism
inferred← citeshttps://doi.org/10.1038/s41467-025-61725-xopenalex-snapshot
Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma
inferred← citeshttps://doi.org/10.1038/s41467-026-69510-0openalex-snapshot
TGFβ-activated PDHB promotes mitochondrial pyruvate metabolism and contributes to human endoderm differentiation via ATP-dependent BRG1
inferred← citeshttps://doi.org/10.1038/s41556-019-0315-4openalex-snapshot
The RNA N6-methyladenosine modification landscape of human fetal tissues
inferred← citeshttps://doi.org/10.1038/s41556-019-0319-0openalex-snapshot
RNA modifications regulating cell fate in cancer
inferred← citeshttps://doi.org/10.1038/s41556-021-00656-3openalex-snapshot
m6A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype
inferred← citeshttps://doi.org/10.1038/s41556-023-01212-xopenalex-snapshot
m6A RNA methylation orchestrates transcriptional dormancy during paused pluripotency
inferred← citeshttps://doi.org/10.1038/s41571-023-00774-xopenalex-snapshot
The roles and implications of RNA m6A modification in cancer
inferred← citeshttps://doi.org/10.1038/s41576-022-00534-0openalex-snapshot
Biological roles of adenine methylation in RNA
inferred← citeshttps://doi.org/10.1038/s41580-019-0168-5openalex-snapshot
Reading, writing and erasing mRNA methylation
inferred← citeshttps://doi.org/10.1038/s41581-019-0135-6openalex-snapshot
Epigenetics and epigenomics in diabetic kidney disease and metabolic memory
inferred← citeshttps://doi.org/10.1038/s41583-019-0244-zopenalex-snapshot
The m6A epitranscriptome: transcriptome plasticity in brain development and function
inferred← citeshttps://doi.org/10.1038/s41583-026-01056-yopenalex-snapshot
m6A in RNA: a key regulator of brain development, function and disease
inferred← citeshttps://doi.org/10.1038/s41588-020-0644-zopenalex-snapshot
Genetic analyses support the contribution of mRNA N6-methyladenosine (m6A) modification to human disease heritability
inferred← citeshttps://doi.org/10.1038/s41588-020-0685-3openalex-snapshot
RNA post-transcriptional modification speaks to chromatin
inferred← citeshttps://doi.org/10.1038/s41594-019-0312-0openalex-snapshot
RNA-modifying enzymes and their function in a chromatin context
inferred← citeshttps://doi.org/10.1038/s41598-020-63355-3openalex-snapshot
Limits in the detection of m6A changes using MeRIP/m6A-seq
inferred← citeshttps://doi.org/10.1038/s41598-024-64517-3openalex-snapshot
Unraveling the independent role of METTL3 in m6A modification and tumor progression in esophageal squamous cell carcinoma
inferred← citeshttps://doi.org/10.1038/s41698-019-0085-2openalex-snapshot
RNAMethyPro: a biologically conserved signature of N6-methyladenosine regulators for predicting survival at pan-cancer level
inferred← citeshttps://doi.org/10.1038/s43587-025-01034-6openalex-snapshot
GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging
inferred← citeshttps://doi.org/10.1038/s44318-024-00299-8openalex-snapshot
METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma
inferred← citeshttps://doi.org/10.1038/s44320-025-00172-8openalex-snapshot
Single cell transcriptional perturbome in pluripotent stem cell models
inferred← citeshttps://doi.org/10.1042/bsr20231186openalex-snapshot
METTL3 promotes osteogenic differentiation of human umbilical cord mesenchymal stem cells by up-regulating m6A modification of circCTTN
inferred← citeshttps://doi.org/10.1042/cs20210449openalex-snapshot
Epigenomic alterations in cancer: mechanisms and therapeutic potential
inferred← citeshttps://doi.org/10.1055/s-0044-1780506openalex-snapshot
Sequencing, Physiological Regulation, and Representative Disease Research Progress of RNA m6A Modification
inferred← citeshttps://doi.org/10.1063/5.0076635openalex-snapshot
Principles for the design of multicellular engineered living systems
inferred← citeshttps://doi.org/10.1073/pnas.2105192118openalex-snapshot
N6-methyladenosine (m 6 A) depletion regulates pluripotency exit by activating signaling pathways in embryonic stem cells
inferred← citeshttps://doi.org/10.1074/jbc.ra117.001298openalex-snapshot
Glycogen synthase kinase-3 (GSK-3) activity regulates mRNA methylation in mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1080/0886022x.2024.2316259openalex-snapshot
Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial–mesenchymal transition
inferred← citeshttps://doi.org/10.1080/15476286.2019.1620060openalex-snapshot
N6-methyladenosine modifications: interactions with novel RNA-binding proteins and roles in signal transduction
inferred← citeshttps://doi.org/10.1080/15476286.2020.1850628openalex-snapshot
Differential roles of YTHDF1 and YTHDF3 in embryonic stem cell-derived cardiomyocyte differentiation
inferred← citeshttps://doi.org/10.1089/scd.2022.0216openalex-snapshot
YTHDF1 Enhances Chondrogenic Differentiation by Activating the Wnt/β-Catenin Signaling Pathway
inferred← citeshttps://doi.org/10.1093/bfgp/elab004openalex-snapshot
Integrative analyses of transcriptome data reveal the mechanisms of post-transcriptional regulation
inferred← citeshttps://doi.org/10.1093/bib/bbac295openalex-snapshot
m6 Aexpress-BHM: predicting m6A regulation of gene expression in multiple-groups context by a Bayesian hierarchical mixture model
inferred← citeshttps://doi.org/10.1093/bioinformatics/btab362openalex-snapshot
Funm6AViewer: a web server and R package for functional analysis of context-specific m6A RNA methylation
inferred← citeshttps://doi.org/10.1093/bioinformatics/btz316openalex-snapshot
FunDMDeep-m6A: identification and prioritization of functional differential m6A methylation genes
inferred← citeshttps://doi.org/10.1093/cvr/cvab160openalex-snapshot
mRNA modifications in cardiovascular biology and disease: with a focus on m6A modification
inferred← citeshttps://doi.org/10.1093/jas/skac034openalex-snapshot
Function of m6A and its regulation of domesticated animals’ complex traits
inferred← citeshttps://doi.org/10.1093/jleuko/qiad061openalex-snapshot
The role of m6A mRNA modification in normal and malignant hematopoiesis
inferred← citeshttps://doi.org/10.1093/jmcb/mjac011openalex-snapshot
Versatile functions of RNA m6A machinery on chromatin
inferred← citeshttps://doi.org/10.1093/nar/gkaa269openalex-snapshot
Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein
inferred← citeshttps://doi.org/10.1093/nar/gkaa692openalex-snapshot
m6A-Atlas: a comprehensive knowledgebase for unraveling theN6-methyladenosine (m6A) epitranscriptome
inferred← citeshttps://doi.org/10.1093/nar/gkab378openalex-snapshot
A comprehensive review of m6A/m6Am RNA methyltransferase structures
inferred← citeshttps://doi.org/10.1093/nar/gkab714openalex-snapshot
m6A-express: uncovering complex and condition-specific m6A regulation of gene expression
inferred← citeshttps://doi.org/10.1093/nar/gkab900openalex-snapshot
The comprehensive interactomes of human adenosine RNA methyltransferases and demethylases reveal distinct functional and regulatory features
inferred← citeshttps://doi.org/10.1093/nar/gkac766openalex-snapshot
The high mobility group protein HMG20A cooperates with the histone reader PHF14 to modulate TGFβ and Hippo pathways
inferred← citeshttps://doi.org/10.1093/nar/gkac830openalex-snapshot
Geographic encoding of transcripts enabled high-accuracy and isoform-aware deep learning of RNA methylation
inferred← citeshttps://doi.org/10.1093/nar/gkae707openalex-snapshot
ALKBH5 governs human endoderm fate by regulating the DKK1/4-mediated Wnt/β-catenin activation
inferred← citeshttps://doi.org/10.1093/nar/gkz1206openalex-snapshot
Integrative network analysis identifies cell-specific trans regulators of m6A
inferred← citeshttps://doi.org/10.1093/narcan/zcag027openalex-snapshot
N 6-methyladenosine promotes temozolomide resistance through mRNA stabilization in glioblastoma cells
inferred← citeshttps://doi.org/10.1093/narmme/ugaf008openalex-snapshot
High-throughput transcriptome analysis reveals a developmental increase in Acvr1c which mediates epigenetic repression of the gene encoding the pubertal brake, Makorin ring finger protein 3
inferred← citeshttps://doi.org/10.1096/fj.201800566rropenalex-snapshot
Unravelling the transcriptional responses of TGF‐β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification
inferred← citeshttps://doi.org/10.1096/fj.201900619rropenalex-snapshot
Epitranscriptomic profiling in human placenta: N6‐methyladenosine modification at the 5′‐untranslated region is related to fetal growth and preeclampsia
inferred← citeshttps://doi.org/10.1096/fj.202202012rrropenalex-snapshot
Long noncoding RNA AI662270 promotes kidney fibrosis through enhancing METTL3 ‐mediated m 6 A modification of CTGF mRNA
inferred← citeshttps://doi.org/10.1096/fj.202301773ropenalex-snapshot
Marrow mesenchymal stem cell mediates diabetic nephropathy progression via modulation of Smad2/3/WTAP/m6A/ENO1 axis
inferred← citeshttps://doi.org/10.1096/fj.202403207ropenalex-snapshot
Mitigation of Ferroptosis in Diabetic Kidney Disease Through Mesenchymal Stem Cell Intervention via the Smad2/3/ METTL3 / S1PR1 Axis
inferred← citeshttps://doi.org/10.1097/hco.0000000000001293openalex-snapshot
RNA modifications in heart failure: current insights and future directions
inferred← citeshttps://doi.org/10.1097/moh.0000000000000506openalex-snapshot
Hematopoietic stem cells: self-renewal and expansion
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