On the public citation graph
Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration
0 signed · 576 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/0471143030.cb0407s30openalex-snapshot
Cryo‐Immunogold Electron Microscopy
inferredcites →https://doi.org/10.1002/j.1460-2075.1987.tb02668.xopenalex-snapshot
Mitochondrial protein import: involvement of the mature part of a cleavable precursor protein in the binding to receptor sites.
inferredcites →https://doi.org/10.1006/excr.2000.4977openalex-snapshot
Involvement of EAT/mcl-1, an Anti-apoptotic bcl-2-Related Gene, in Murine Embryogenesis and Human Development
inferredcites →https://doi.org/10.1007/s00439-001-0633-yopenalex-snapshot
Mutation spectrum and splicing variants in the OPA1 gene
inferredcites →https://doi.org/10.1016/0009-3084(86)90067-8openalex-snapshot
Lipid polymorphism and the roles of lipids in membranes
inferredcites →https://doi.org/10.1016/0014-5793(68)80045-6openalex-snapshot
Turnover of outer and inner membrane proteins of rat liver mitochondria
inferredcites →https://doi.org/10.1016/0092-8674(92)90123-topenalex-snapshot
Induction of apoptosis in fibroblasts by c-myc protein
inferredcites →https://doi.org/10.1016/0092-8674(93)80065-mopenalex-snapshot
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
inferredcites →https://doi.org/10.1016/j.bbabio.2008.04.007openalex-snapshot
Is supercomplex organization of the respiratory chain required for optimal electron transfer activity?
inferredcites →https://doi.org/10.1016/j.bbamcr.2006.04.006openalex-snapshot
Structure and dynamics of the mitochondrial inner membrane cristae
inferredcites →https://doi.org/10.1016/j.bbrc.2005.02.010openalex-snapshot
Active oligomeric ATP synthases in mammalian mitochondria
inferredcites →https://doi.org/10.1016/j.bbrc.2009.11.086openalex-snapshot
MCL-1V, a novel mouse antiapoptotic MCL-1 variant, generated by RNA splicing at a non-canonical splicing pair
inferredcites →https://doi.org/10.1016/j.biocel.2009.01.011openalex-snapshot
Mitochondrial F1F0-ATP synthase and organellar internal architecture
inferredcites →https://doi.org/10.1016/j.ccr.2006.03.027openalex-snapshot
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
inferredcites →https://doi.org/10.1016/j.ccr.2006.09.006openalex-snapshot
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance
inferredcites →https://doi.org/10.1016/j.cell.2005.06.009openalex-snapshot
Mule/ARF-BP1, a BH3-Only E3 Ubiquitin Ligase, Catalyzes the Polyubiquitination of Mcl-1 and Regulates Apoptosis
inferredcites →https://doi.org/10.1016/j.cell.2006.06.010openalex-snapshot
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
inferredcites →https://doi.org/10.1016/j.cell.2006.06.025openalex-snapshot
OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion
inferredcites →https://doi.org/10.1016/j.cell.2007.06.026openalex-snapshot
Mitochondrial Fusion Protects against Neurodegeneration in the Cerebellum
inferredcites →https://doi.org/10.1016/j.cell.2008.01.036openalex-snapshot
Stems Cells and the Pathways to Aging and Cancer
inferredcites →https://doi.org/10.1016/j.cell.2008.10.048openalex-snapshot
Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
inferredcites →https://doi.org/10.1016/j.cell.2010.02.026openalex-snapshot
Mitochondrial Fusion Is Required for mtDNA Stability in Skeletal Muscle and Tolerance of mtDNA Mutations
inferredcites →https://doi.org/10.1016/j.cell.2011.02.013openalex-snapshot
Hallmarks of Cancer: The Next Generation
inferredcites →https://doi.org/10.1016/j.cmet.2008.06.001openalex-snapshot
Regulation of Mitochondrial Structure and Function by the F1Fo-ATPase Inhibitor Protein, IF1
inferredcites →https://doi.org/10.1016/j.coi.2007.06.002openalex-snapshot
Life and death during hematopoietic differentiation
inferredcites →https://doi.org/10.1016/j.drudis.2007.12.008openalex-snapshot
Advances in measuring cellular bioenergetics using extracellular flux
inferredcites →https://doi.org/10.1016/j.febslet.2005.09.065openalex-snapshot
Structure of dimeric ATP synthase from mitochondria: An angular association of monomers induces the strong curvature of the inner membrane
inferredcites →https://doi.org/10.1016/j.febslet.2010.06.036openalex-snapshot
Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells
inferredcites →https://doi.org/10.1016/j.febslet.2010.07.013openalex-snapshot
The fast‐mobility isoform of mouse Mcl‐1 is a mitochondrial matrix‐localized protein with attenuated anti‐apoptotic activity
inferredcites →https://doi.org/10.1016/j.gde.2008.02.003openalex-snapshot
Brick by brick: metabolism and tumor cell growth
inferredcites →https://doi.org/10.1016/j.jhep.2005.09.010openalex-snapshot
Mcl-1 overexpression in hepatocellular carcinoma: A potential target for antisense therapy
inferredcites →https://doi.org/10.1016/j.molcel.2006.01.034openalex-snapshot
Role for CED-9 and Egl-1 as Regulators of Mitochondrial Fission and Fusion Dynamics
inferredcites →https://doi.org/10.1016/j.molcel.2006.02.009openalex-snapshot
Glycogen Synthase Kinase-3 Regulates Mitochondrial Outer Membrane Permeabilization and Apoptosis by Destabilization of MCL-1
inferredcites →https://doi.org/10.1016/j.molcel.2008.08.002openalex-snapshot
Bax- or Bak-Induced Mitochondrial Fission Can Be Uncoupled from Cytochrome c Release
inferredcites →https://doi.org/10.1016/j.molcel.2008.10.021openalex-snapshot
Respiratory Active Mitochondrial Supercomplexes
inferredcites →https://doi.org/10.1016/j.molcel.2009.10.011openalex-snapshot
Emerging Role for Members of the Bcl-2 Family in Mitochondrial Morphogenesis
inferredcites →https://doi.org/10.1016/j.molcel.2010.01.025openalex-snapshot
The BCL-2 Family Reunion
inferredcites →https://doi.org/10.1016/j.molcel.2010.11.030openalex-snapshot
The Soluble Form of Bax Regulates Mitochondrial Fusion via MFN2 Homotypic Complexes
inferredcites →https://doi.org/10.1016/j.stem.2010.07.011openalex-snapshot
The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche
inferredcites →https://doi.org/10.1016/s0005-2728(02)00274-8openalex-snapshot
Is there a relationship between the supramolecular organization of the mitochondrial ATP synthase and the formation of cristae?
inferredcites →https://doi.org/10.1016/s0014-5793(00)01809-3openalex-snapshot
In vivo localisation and stability of human Mcl‐1 using green fluorescent protein (GFP) fusion proteins
inferredcites →https://doi.org/10.1016/s0014-5793(03)00633-1openalex-snapshot
The cristal membrane of mitochondria is the principal site of oxidative phosphorylation
inferredcites →https://doi.org/10.1016/s0021-9258(17)30124-2openalex-snapshot
Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells.
inferredcites →https://doi.org/10.1016/s0021-9258(19)69029-0openalex-snapshot
An NADH-linked spectrophotometric assay for pyruvate dehydrogenase complex in crude tissue homogenates.
inferredcites →https://doi.org/10.1016/s0021-9258(19)75338-1openalex-snapshot
A Naturally Occurring Inhibitor of Mitochondrial Adenosine Triphosphatase
inferredcites →https://doi.org/10.1016/s0165-0270(97)00204-5openalex-snapshot
Cytochrome c oxidase assay in minute amounts of human skeletal muscle using single wavelength spectrophotometers
inferredcites →https://doi.org/10.1016/s0303-7207(03)00095-9openalex-snapshot
Islet cell hyperplasia in transgenic mice overexpressing EAT/mcl-1, a bcl-2 related gene
inferredcites →https://doi.org/10.1016/s0304-3835(01)00842-4openalex-snapshot
Expression of apoptotic regulators and their significance in cervical cancer
inferredcites →https://doi.org/10.1016/s0968-0004(00)01609-1openalex-snapshot
The internal structure of mitochondria
inferredcites →https://doi.org/10.1016/s1046-2023(02)00034-8openalex-snapshot
Isolation of biogenetically competent mitochondria from mammalian tissues and cultured cells
inferredcites →https://doi.org/10.1016/s1097-2765(01)00320-3openalex-snapshot
BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis
inferredcites →https://doi.org/10.1016/s1534-5807(01)00055-7openalex-snapshot
The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis
inferredcites →https://doi.org/10.1038/13014openalex-snapshot
The dynamin-related GTPase Dnm1 regulates mitochondrial fission in yeast
inferredcites →https://doi.org/10.1038/191144a0openalex-snapshot
Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism
inferredcites →https://doi.org/10.1038/35004029openalex-snapshot
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
inferredcites →https://doi.org/10.1038/359552a0openalex-snapshot
Apoptotic cell death induced by c-myc is inhibited by bcl-2
inferredcites →https://doi.org/10.1038/cdd.2008.20openalex-snapshot
Cancer stem cells – old concepts, new insights
inferredcites →https://doi.org/10.1038/cddis.2010.86openalex-snapshot
Obatoclax induces Atg7-dependent autophagy independent of beclin-1 and BAX/BAK
inferredcites →https://doi.org/10.1038/emboj.2008.35openalex-snapshot
Dimer ribbons of ATP synthase shape the inner mitochondrial membrane
inferredcites →https://doi.org/10.1038/modpathol.3800750openalex-snapshot
Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma
inferredcites →https://doi.org/10.1038/nature02067openalex-snapshot
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1
inferredcites →https://doi.org/10.1038/nature03579openalex-snapshot
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
inferredcites →https://doi.org/10.1038/nature05111openalex-snapshot
Role of Bax and Bak in mitochondrial morphogenesis
inferredcites →https://doi.org/10.1038/nature08646openalex-snapshot
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
inferredcites →https://doi.org/10.1038/nature08822openalex-snapshot
The landscape of somatic copy-number alteration across human cancers
inferredcites →https://doi.org/10.1038/nature09732openalex-snapshot
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
inferredcites →https://doi.org/10.1038/ncb2220openalex-snapshot
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
inferredcites →https://doi.org/10.1038/ncb2330openalex-snapshot
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase
inferredcites →https://doi.org/10.1038/nchembio.391openalex-snapshot
The MCL-1 BH3 Helix is an Exclusive MCL-1 Inhibitor and Apoptosis Sensitizer
inferredcites →https://doi.org/10.1038/ni0503-410openalex-snapshot
Apoptosis in the development and maintenance of the immune system
inferredcites →https://doi.org/10.1038/nrc883openalex-snapshot
The Bcl2 family: regulators of the cellular life-or-death switch
inferredcites →https://doi.org/10.1038/nrm1313openalex-snapshot
The dynamin superfamily: universal membrane tubulation and fission molecules?
inferredcites →https://doi.org/10.1038/nrm2275openalex-snapshot
Functions and dysfunctions of mitochondrial dynamics
inferredcites →https://doi.org/10.1038/nrm2308openalex-snapshot
The BCL-2 protein family: opposing activities that mediate cell death
inferredcites →https://doi.org/10.1038/nrm2959openalex-snapshot
Mitochondrial protein import: from proteomics to functional mechanisms
inferredcites →https://doi.org/10.1038/nsb966openalex-snapshot
The structure of bovine F1-ATPase in complex with its regulatory protein IF1
inferredcites →https://doi.org/10.1038/onc.2009.448openalex-snapshot
Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation
inferredcites →https://doi.org/10.1038/sj.cdd.4402107openalex-snapshot
Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis
inferredcites →https://doi.org/10.1038/sj.cdd.4402182openalex-snapshot
Apoptosis in the development of the immune system
inferredcites →https://doi.org/10.1038/sj.emboj.7601184openalex-snapshot
Regulation of mitochondrial morphology through proteolytic cleavage of OPA1
inferredcites →https://doi.org/10.1038/sj.emboj.7601972openalex-snapshot
Quality control of mitochondria: protection against neurodegeneration and ageing
inferredcites →https://doi.org/10.1038/sj.leu.2403784openalex-snapshot
Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival
inferredcites →https://doi.org/10.1038/sj.onc.1207692openalex-snapshot
MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol
inferredcites →https://doi.org/10.1042/bc20080022openalex-snapshot
Supramolecular organization of the yeast F1Fo‐ATP synthase
inferredcites →https://doi.org/10.1056/nejmp078040openalex-snapshot
Mitochondrial Dynamics in Disease
inferredcites →https://doi.org/10.1073/pnas.0237315100openalex-snapshot
Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase)
inferredcites →https://doi.org/10.1073/pnas.0503893102openalex-snapshot
Structure of dimeric mitochondrial ATP synthase: Novel F 0 bridging features and the structural basis of mitochondrial cristae biogenesis
inferredcites →https://doi.org/10.1073/pnas.0709443104openalex-snapshot
Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis
inferredcites →https://doi.org/10.1073/pnas.0709747104openalex-snapshot
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
inferredcites →https://doi.org/10.1073/pnas.0810199105openalex-snapshot
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
inferredcites →https://doi.org/10.1073/pnas.0904875106openalex-snapshot
A hyperfused mitochondrial state achieved at G 1 –S regulates cyclin E buildup and entry into S phase
inferredcites →https://doi.org/10.1073/pnas.90.8.3516openalex-snapshot
MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2.
inferredcites →https://doi.org/10.1074/jbc.m000915200openalex-snapshot
Myeloid Cell Leukemia 1 Is Phosphorylated through Two Distinct Pathways, One Associated with Extracellular Signal-regulated Kinase Activation and the Other with G2/M Accumulation or Protein Phosphatase 1/2A Inhibition
inferredcites →https://doi.org/10.1074/jbc.m006626200openalex-snapshot
Regulation of Apoptosis and Cell Cycle Progression by MCL1
inferredcites →https://doi.org/10.1074/jbc.m110.179101openalex-snapshot
Akt Requires Glucose Metabolism to Suppress Puma Expression and Prevent Apoptosis of Leukemic T Cells
inferredcites →https://doi.org/10.1074/jbc.m111.218321openalex-snapshot
Mitochondrion-dependent N-terminal Processing of Outer Membrane Mcl-1 Protein Removes an Essential Mule/Lasu1 Protein-binding Site
inferredcites →https://doi.org/10.1074/jbc.m207951200openalex-snapshot
Phosphorylation and Inactivation of Myeloid Cell Leukemia 1 by JNK in Response to Oxidative Stress
inferredcites →https://doi.org/10.1074/jbc.m308366200openalex-snapshot
Cardiolipin Stabilizes Respiratory Chain Supercomplexes
inferredcites →https://doi.org/10.1074/jbc.m400920200openalex-snapshot
Loss of the Intermembrane Space Protein Mgm1/OPA1 Induces Swelling and Localized Constrictions along the Lengths of Mitochondria
inferredcites →https://doi.org/10.1074/jbc.m408910200openalex-snapshot
Fzo1, a Protein Involved in Mitochondrial Fusion, Inhibits Apoptosis
inferredcites →https://doi.org/10.1074/jbc.m411434200openalex-snapshot
Solution Structure of Prosurvival Mcl-1 and Characterization of Its Binding by Proapoptotic BH3-only Ligands
inferredcites →https://doi.org/10.1074/jbc.m501599200openalex-snapshot
Activated Mitofusin 2 Signals Mitochondrial Fusion, Interferes with Bax Activation, and Reduces Susceptibility to Radical Induced Depolarization
inferredcites →https://doi.org/10.1074/jbc.m503062200openalex-snapshot
Disruption of Fusion Results in Mitochondrial Heterogeneity and Dysfunction
inferredcites →https://doi.org/10.1074/jbc.m512334200openalex-snapshot
Mitochondrial Membrane Potential Is Dependent on the Oligomeric State of F1F0-ATP Synthase Supracomplexes
inferredcites →https://doi.org/10.1074/jbc.m700938200openalex-snapshot
N-terminal Truncation of Antiapoptotic MCL1, but Not G2/M-induced Phosphorylation, Is Associated with Stabilization and Abundant Expression in Tumor Cells
inferredcites →https://doi.org/10.1074/jbc.m703812200openalex-snapshot
Mitofusin 2 Protects Cerebellar Granule Neurons against Injury-induced Cell Death
inferredcites →https://doi.org/10.1074/jbc.m706408200openalex-snapshot
The N Terminus of the Anti-apoptotic BCL-2 Homologue MCL-1 Regulates Its Localization and Function
inferredcites →https://doi.org/10.1083/jcb.128.6.1173openalex-snapshot
The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2.
inferredcites →https://doi.org/10.1083/jcb.200211046openalex-snapshot
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
inferredcites →https://doi.org/10.1083/jcb.200212059openalex-snapshot
Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol
inferredcites →https://doi.org/10.1083/jcb.200309082openalex-snapshot
Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis
inferredcites →https://doi.org/10.1083/jcb.200605138openalex-snapshot
Dynamic subcompartmentalization of the mitochondrial inner membrane
inferredcites →https://doi.org/10.1083/jcb.200703099openalex-snapshot
Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells
inferredcites →https://doi.org/10.1083/jcb.200704110openalex-snapshot
OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L
inferredcites →https://doi.org/10.1083/jcb.200708096openalex-snapshot
A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation
inferredcites →https://doi.org/10.1083/jcb.200809060openalex-snapshot
Bcl-xL increases mitochondrial fission, fusion, and biomass in neurons
inferredcites →https://doi.org/10.1083/jcb.201107053openalex-snapshot
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria
inferredcites →https://doi.org/10.1083/jcb.37.2.345openalex-snapshot
ULTRASTRUCTURAL BASES FOR METABOLICALLY LINKED MECHANICAL ACTIVITY IN MITOCHONDRIA
inferredcites →https://doi.org/10.1084/jem.191.2.253openalex-snapshot
The Role of Apoptosis in the Regulation of Hematopoietic Stem Cells
inferredcites →https://doi.org/10.1084/jem.20111363openalex-snapshot
The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis
inferredcites →https://doi.org/10.1091/mbc.12.8.2245openalex-snapshot
Dynamin-related Protein Drp1 Is Required for Mitochondrial Division in Mammalian Cells
inferredcites →https://doi.org/10.1091/mbc.e04-04-0294openalex-snapshot
Roles of the Mammalian Mitochondrial Fission and Fusion Mediators Fis1, Drp1, and Opa1 in Apoptosis
inferredcites →https://doi.org/10.1093/emboj/19.8.1777openalex-snapshot
Supercomplexes in the respiratory chains of yeast and mammalian mitochondria
inferredcites →https://doi.org/10.1093/emboj/21.3.221openalex-snapshot
The ATP synthase is involved in generating mitochondrial cristae morphology
inferredcites →https://doi.org/10.1093/hmg/ddi270openalex-snapshot
Emerging functions of mammalian mitochondrial fusion and fission
inferredcites →https://doi.org/10.1101/gad.12.15.2424openalex-snapshot
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
inferredcites →https://doi.org/10.1101/gad.1304105openalex-snapshot
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x L , but not Bcl-2, until displaced by BH3-only proteins
inferredcites →https://doi.org/10.1101/gad.14.1.23openalex-snapshot
Mcl-1 deficiency results in peri-implantation embryonic lethality
inferredcites →https://doi.org/10.1101/gad.182980.111openalex-snapshot
Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia
inferredcites →https://doi.org/10.1101/gad.897601openalex-snapshot
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
inferredcites →https://doi.org/10.1111/j.1365-2559.2005.02118.xopenalex-snapshot
Overexpression of anti‐apoptotic Mcl‐1 in testicular germ cell tumours
inferredcites →https://doi.org/10.1111/j.1432-1033.1974.tb03899.xopenalex-snapshot
The Influence of Respiration and ATP Hydrolysis on the Proton‐Electrochemical Gradient across the Inner Membrane of Rat‐Liver Mitochondria as Determined by Ion Distribution
inferredcites →https://doi.org/10.1126/science.1059108openalex-snapshot
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
inferredcites →https://doi.org/10.1126/science.1099793openalex-snapshot
Structural Basis of Mitochondrial Tethering by Mitofusin Complexes
inferredcites →https://doi.org/10.1126/science.1106114openalex-snapshot
Obligate Role of Anti-Apoptotic MCL-1 in the Survival of Hematopoietic Stem Cells
inferredcites →https://doi.org/10.1126/science.122.3168.501openalex-snapshot
Nutrition Needs of Mammalian Cells in Tissue Culture
inferredcites →https://doi.org/10.1126/science.1378649openalex-snapshot
Role for c-myc in Activation-Induced Apoptotic Cell Death in T Cell Hybridomas
inferredcites →https://doi.org/10.1126/science.283.5407.1482openalex-snapshot
Mitochondrial Diseases in Man and Mouse
inferredcites →https://doi.org/10.1126/science.7878471openalex-snapshot
Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice
inferredcites →https://doi.org/10.1128/mcb.00279-09openalex-snapshot
Mcl-1 Integrates the Opposing Actions of Signaling Pathways That Mediate Survival and Apoptosis
inferredcites →https://doi.org/10.1128/mcb.00620-06openalex-snapshot
Degradation of Mcl-1 by β-TrCP Mediates Glycogen Synthase Kinase 3-Induced Tumor Suppression and Chemosensitization
inferredcites →https://doi.org/10.1128/mcb.01266-09openalex-snapshot
Ubiquitin-Independent Degradation of Antiapoptotic MCL-1
inferredcites →https://doi.org/10.1128/mcb.01767-05openalex-snapshot
Cytochrome c Oxidase Is Required for the Assembly/Stability of Respiratory Complex I in Mouse Fibroblasts
inferredcites →https://doi.org/10.1128/mcb.19.9.6195openalex-snapshot
The Antiapoptotic Gene mcl-1 Is Up-Regulated by the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway through a Transcription Factor Complex Containing CREB
inferredcites →https://doi.org/10.1128/mcb.21.15.5063-5070.2001openalex-snapshot
Apoptosis Triggered by Myc-Induced Suppression of Bcl-X L or Bcl-2 Is Bypassed during Lymphomagenesis
inferredcites →https://doi.org/10.1146/annurev.genet.38.072902.093019openalex-snapshot
Mitochondrial Morphology and Dynamics in Yeast and Multicellular Eukaryotes
inferredcites →https://doi.org/10.1152/ajpcell.00263.2006openalex-snapshot
Kinetics of integrated electron transfer in the mitochondrial respiratory chain: random collisions vs. solid state electron channeling
inferredcites →https://doi.org/10.1152/ajpcell.00607.2004openalex-snapshot
Inhibition of complex I of the electron transport chain causes O 2 − ·-mediated mitochondrial outgrowth
inferredcites →https://doi.org/10.1152/ajpcell.1983.245.1.c40openalex-snapshot
Energy metabolism of preimplantation mammalian blastocysts
inferredcites →https://doi.org/10.1152/ajpregu.00504.2004openalex-snapshot
Hypoxia accelerates nitric oxide-dependent inhibition of mitochondrial complex I in activated macrophages
inferredcites →https://doi.org/10.1158/0008-5472.can-03-1101openalex-snapshot
Energy Substrate Modulates Mitochondrial Structure and Oxidative Capacity in Cancer Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-07-5836openalex-snapshot
ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor
inferredcites →https://doi.org/10.1172/jci39964openalex-snapshot
Mcl1 haploinsufficiency protects mice from Myc-induced acute myeloid leukemia
inferredcites →https://doi.org/10.1182/blood-2006-03-013771openalex-snapshot
The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages
inferredcites →https://doi.org/10.1182/blood-2008-05-157131openalex-snapshot
Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers
inferredcites →https://doi.org/10.1182/blood-2008-05-159145openalex-snapshot
Selective roles for antiapoptotic MCL-1 during granulocyte development and macrophage effector function
inferredcites →https://doi.org/10.1182/blood-2010-04-281071openalex-snapshot
Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance
inferredcites →https://doi.org/10.1182/blood.v89.2.630openalex-snapshot
Mcl-1, a Bcl-2 Family Member, Delays the Death of Hematopoietic Cells Under a Variety of Apoptosis-Inducing Conditions
inferredcites →https://doi.org/10.1182/blood.v91.3.991openalex-snapshot
Elevated Expression of the Apoptotic Regulator Mcl-1 at the Time of Leukemic Relapse
inferredcites →https://doi.org/10.1182/blood.v96.5.1764openalex-snapshot
Mcl-1 is a common target of stem cell factor and interleukin-5 for apoptosis prevention activity via MEK/MAPK and PI-3K/Akt pathways
inferredcites →https://doi.org/10.1182/blood.v97.12.3902openalex-snapshot
MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes
inferredcites →https://doi.org/10.1242/dev.122.4.1165openalex-snapshot
Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex
inferredcites →https://doi.org/10.1242/dev.127.22.4949openalex-snapshot
Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly
inferredcites →https://doi.org/10.1242/jcs.01134openalex-snapshot
Organization and dynamics of human mitochondrial DNA
inferredcites →https://doi.org/10.1523/jneurosci.2478-07.2007openalex-snapshot
Opposite Regulation of Oligodendrocyte Apoptosis by JNK3 and Pin1 after Spinal Cord Injury
inferredcites →https://doi.org/10.1523/jneurosci.4940-07.2008openalex-snapshot
Mcl-1 Is a Key Regulator of Apoptosis during CNS Development and after DNA Damage
inferredcites →https://doi.org/10.1530/rep.1.00458openalex-snapshot
Regulatory roles for mitochondria in the peri-implantation mouse blastocyst: possible origins and developmental significance of differential ΔΨm
inferredcites →https://doi.org/10.2174/156652408783769580openalex-snapshot
Unique Biology of Mcl-1: Therapeutic Opportunities in Cancer
inferredcites →https://doi.org/10.4049/jimmunol.181.1.521openalex-snapshot
The Anti-Apoptotic Bcl-2 Family Member Mcl-1 Promotes T Lymphocyte Survival at Multiple Stages
inferredcites →https://doi.org/10.4161/cbt.4.3.1496openalex-snapshot
Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.3189387openalex-extracted
Genome-Scale CRISPR Screening Identifies Novel Human Pluripotent Gene Networks
inferred← citeshttps://doi.org/10.1002/1878-0261.12559openalex-snapshot
Targeting CDK9 for treatment of colorectal cancer
inferred← citeshttps://doi.org/10.1002/ange.6256371openalex-snapshot
Multidimensional Exploration of Platinum Complexes for Cancer Therapy
inferred← citeshttps://doi.org/10.1002/anie.6256371openalex-snapshot
Multidimensional Exploration of Platinum Complexes for Cancer Therapy
inferred← citeshttps://doi.org/10.1002/ar.23454openalex-snapshot
Nutrient Starvation Sensitizes Human Ovarian Cancer SKOV3 Cells to BH3 Mimetic via Modulation of Mitochondrial Dynamics
inferred← citeshttps://doi.org/10.1002/bies.201300011openalex-snapshot
Mitochondrial fission‐fusion as an emerging key regulator of cell proliferation and differentiation
inferred← citeshttps://doi.org/10.1002/cbf.3121openalex-snapshot
Inhibition of MCL‐1 by obatoclax sensitizes Sp2/0‐Ag14 hybridoma cells to glutamine deprivation‐induced apoptosis
inferred← citeshttps://doi.org/10.1002/cnr2.1942openalex-snapshot
Mitochondrion: Main organelle in orchestrating cancer escape from chemotherapy
inferred← citeshttps://doi.org/10.1002/med.21516openalex-snapshot
Selective targeting of antiapoptotic BCL‐2 proteins in cancer
inferred← citeshttps://doi.org/10.1002/smll.201601465openalex-snapshot
Controllable Large-Scale Transfection of Primary Mammalian Cardiomyocytes on a Nanochannel Array Platform
inferred← citeshttps://doi.org/10.1002/term.2148openalex-snapshot
RHEB: a potential regulator of chondrocyte phenotype for cartilage tissue regeneration
inferred← citeshttps://doi.org/10.1007/978-1-4614-9302-0_4openalex-snapshot
Bcl-2 Family and Their Therapeutic Potential
inferred← citeshttps://doi.org/10.1007/978-1-4614-9302-0_9openalex-snapshot
The Complex Interplay Between Metabolism and Apoptosis
inferred← citeshttps://doi.org/10.1007/978-3-319-41324-2_9openalex-snapshot
Evolution of the BCL-2-Regulated Apoptotic Pathway
inferred← citeshttps://doi.org/10.1007/978-3-319-42139-1_10openalex-snapshot
Altering Mitochondrial Fusion and Fission Protein Levels Rescues Parkin and PINK1 Loss-of-Function Phenotypes
inferred← citeshttps://doi.org/10.1007/s00018-022-04172-xopenalex-snapshot
MCL1 alternative polyadenylation is essential for cell survival and mitochondria morphology
inferred← citeshttps://doi.org/10.1007/s00204-014-1448-7openalex-snapshot
The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update
inferred← citeshttps://doi.org/10.1007/s10495-013-0868-9openalex-snapshot
Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1
inferred← citeshttps://doi.org/10.1007/s10495-016-1300-zopenalex-snapshot
Dynamic quantitative proteomics characterization of TNF-α-induced necroptosis
inferred← citeshttps://doi.org/10.1007/s10495-022-01756-7openalex-snapshot
c-Myc plays a critical role in the antileukemic activity of the Mcl-1-selective inhibitor AZD5991 in acute myeloid leukemia
inferred← citeshttps://doi.org/10.1007/s10495-023-01917-2openalex-snapshot
Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak
inferred← citeshttps://doi.org/10.1007/s10549-018-5022-5openalex-snapshot
Rationally derived drug combinations with the novel Mcl-1 inhibitor EU-5346 in breast cancer
inferred← citeshttps://doi.org/10.1007/s10753-026-02548-wopenalex-snapshot
Mitophagy in Metabolic Dysfunction-Associated Fatty Liver Disease: Mechanisms, Regulatory Networks, and Therapeutic Perspectives
inferred← citeshttps://doi.org/10.1016/b978-0-12-394447-4.30046-3openalex-snapshot
Mitochondria in Cell Death Regulation
inferred← citeshttps://doi.org/10.1016/b978-0-12-801415-8.00004-7openalex-snapshot
Photoactivatable Green Fluorescent Protein-Based Visualization and Quantification of Mitochondrial Fusion and Mitochondrial Network Complexity in Living Cells
inferred← citeshttps://doi.org/10.1016/b978-0-323-31696-5.00028-0openalex-snapshot
Immunologic Repercussions of Cell Death
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2019.12.001openalex-snapshot
Bcl-2 family proteins, beyond the veil
inferred← citeshttps://doi.org/10.1016/j.bbadis.2016.11.026openalex-snapshot
VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease
inferred← citeshttps://doi.org/10.1016/j.bbadis.2024.167599openalex-snapshot
USP13 inhibition exacerbates mitochondrial dysfunction and acute kidney injury by acting on MCL-1
inferred← citeshttps://doi.org/10.1016/j.bbagen.2017.11.021openalex-snapshot
Modulation of Mcl-1 transcription by serum deprivation sensitizes cancer cells to cisplatin
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2013.01.008openalex-snapshot
Throwing a monkey wrench in the motor: Targeting DExH/D box proteins with small molecule inhibitors
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2014.06.002openalex-snapshot
Regulating cell death at, on, and in membranes
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2015.03.012openalex-snapshot
Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2015.05.014openalex-snapshot
Oncostatin M-dependent Mcl-1 induction mediated by JAK1/2-STAT1/3 and CREB contributes to bioenergetic improvements and protective effects against mitochondrial dysfunction in cortical neurons
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2017.04.009openalex-snapshot
p62-Mediated mitochondrial clustering attenuates apoptosis induced by mitochondrial depolarization
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2023.119487openalex-snapshot
Phospholipase A2-activating protein induces mitophagy through anti-apoptotic MCL1-mediated NLRX1 oligomerization
inferred← citeshttps://doi.org/10.1016/j.bbcan.2017.08.004openalex-snapshot
Approaches and techniques to characterize cancer metabolism in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.bbrc.2015.01.137openalex-snapshot
Calcium and mitochondria in the regulation of cell death
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.12.104openalex-snapshot
Mcl-1 inhibits Mff-mediated mitochondrial fragmentation and apoptosis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.154218openalex-snapshot
Mitochondrial genome alterations in cancer: From mutations and epigenetics to targeted therapiesack
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115759openalex-snapshot
Acquired resistance to venetoclax plus azacitidine in acute myeloid leukemia: In vitro models and mechanisms
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2017.06.034openalex-snapshot
Sensitivity to antitubulin chemotherapeutics is potentiated by a photoactivable nanoliposome
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119295openalex-snapshot
Leukemic stem cells as drivers of therapeutic resistance in acute myeloid leukemia
inferred← citeshttps://doi.org/10.1016/j.bmcl.2020.127717openalex-snapshot
Interdiction at a protein-protein interface: MCL-1 inhibitors for oncology
inferred← citeshttps://doi.org/10.1016/j.bone.2013.09.020openalex-snapshot
Anti-apoptotic Bcl-2 family member Mcl-1 regulates cell viability and bone-resorbing activity of osteoclasts
inferred← citeshttps://doi.org/10.1016/j.canlet.2013.09.042openalex-snapshot
Targeting Mcl-1 for multiple myeloma (MM) therapy: Drug-induced generation of Mcl-1 fragment Mcl-1128–350 triggers MM cell death via c-Jun upregulation
inferred← citeshttps://doi.org/10.1016/j.ccell.2018.11.004openalex-snapshot
BH3-Mimetic Drugs: Blazing the Trail for New Cancer Medicines
inferred← citeshttps://doi.org/10.1016/j.ccell.2019.03.007openalex-snapshot
Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis
inferred← citeshttps://doi.org/10.1016/j.cellsig.2021.109933openalex-snapshot
The role of post-translational modifications in the regulation of MCL1
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.05.013openalex-snapshot
Ubiquitin-Dependent Degradation of Mitochondrial Proteins Regulates Energy Metabolism
inferred← citeshttps://doi.org/10.1016/j.celrep.2019.03.043openalex-snapshot
Genome-Scale CRISPR Screens Identify Human Pluripotency-Specific Genes
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111445openalex-snapshot
MCL-1 is a master regulator of cancer dependency on fatty acid oxidation
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.113176openalex-snapshot
Targeting MCL-1 triggers DNA damage and an anti-proliferative response independent from apoptosis induction
inferred← citeshttps://doi.org/10.1016/j.celrep.2025.115804openalex-snapshot
Cell death and cancer: Metabolic interconnections
inferred← citeshttps://doi.org/10.1016/j.chembiol.2013.10.009openalex-snapshot
Death upon a Kiss: Mitochondrial Outer Membrane Composition and Organelle Communication Govern Sensitivity to BAK/BAX-Dependent Apoptosis
inferred← citeshttps://doi.org/10.1016/j.chom.2017.09.001openalex-snapshot
The Epstein-Barr Virus Regulome in Lymphoblastoid Cells
inferred← citeshttps://doi.org/10.1016/j.cmet.2017.09.009openalex-snapshot
MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation
inferred← citeshttps://doi.org/10.1016/j.cophys.2018.03.005openalex-snapshot
BH3-dependent and independent activation of BAX and BAK in mitochondrial apoptosis
inferred← citeshttps://doi.org/10.1016/j.devcel.2021.03.033openalex-snapshot
Mechanistic connections between mitochondrial biology and regulated cell death
inferred← citeshttps://doi.org/10.1016/j.drup.2019.100643openalex-snapshot
What sustains the multidrug resistance phenotype beyond ABC efflux transporters? Looking beyond the tip of the iceberg
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.117311openalex-snapshot
Combining mendelian randomization analysis and network toxicology strategy to identify causality and underlying mechanisms of environmental pollutants with glioblastoma: A study of Methyl-4-hydroxybenzoate
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.117168openalex-snapshot
Chemical dissection of selective myeloid leukemia-1 inhibitors: How they were found and evolved
inferred← citeshttps://doi.org/10.1016/j.exphem.2018.09.006openalex-snapshot
A rare subgroup of leukemia stem cells harbors relapse-inducing potential in acute lymphoblastic leukemia
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.05.038openalex-snapshot
Myricetin prevents thapsigargin-induced CDK5-P66Shc signalosome mediated pancreatic β-cell dysfunction
inferred← citeshttps://doi.org/10.1016/j.gene.2015.04.030openalex-snapshot
Insights into protein interaction networks reveal non-receptor kinases as significant druggable targets for psoriasis
inferred← citeshttps://doi.org/10.1016/j.gene.2016.04.054openalex-snapshot
MCL-1 is the key target of adjuvant chemotherapy to reverse the cisplatin-resistance in NSCLC
inferred← citeshttps://doi.org/10.1016/j.gene.2025.149685openalex-snapshot
Mitochondrial metabolism: Critical mechanisms underpinning normal hematopoietic stem cell and acute myeloid leukemia stem cell function
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e41355openalex-snapshot
Inducing apoptosis in acute myeloid leukemia; mechanisms and limitations
inferred← citeshttps://doi.org/10.1016/j.hoc.2017.04.005openalex-snapshot
Mechanisms of Resistance to FLT3 Inhibitors and the Role of the Bone Marrow Microenvironment
inferred← citeshttps://doi.org/10.1016/j.imbio.2015.02.004openalex-snapshot
SOCS3 promotes inflammation and apoptosis via inhibiting JAK2/STAT3 signaling pathway in 3T3-L1 adipocyte
inferred← citeshttps://doi.org/10.1016/j.isci.2020.101015openalex-snapshot
MCL-1 Inhibition by Selective BH3 Mimetics Disrupts Mitochondrial Dynamics Causing Loss of Viability and Functionality of Human Cardiomyocytes
inferred← citeshttps://doi.org/10.1016/j.jdermsci.2017.04.011openalex-snapshot
Imiquimod-induced autophagy is regulated by ER stress-mediated PKR activation in cancer cells
inferred← citeshttps://doi.org/10.1016/j.jhep.2018.01.026openalex-snapshot
Fibroblast growth factor receptor inhibition induces loss of matrix MCL1 and necrosis in cholangiocarcinoma
inferred← citeshttps://doi.org/10.1016/j.jmb.2018.07.022openalex-snapshot
Sweet Killing in Obesity and Diabetes: The Metabolic Role of the BH3-only Protein BIM
inferred← citeshttps://doi.org/10.1016/j.joca.2019.05.024openalex-snapshot
RHEB gene therapy maintains the chondrogenic characteristics and protects cartilage tissue from degenerative damage during experimental murine osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.jsbmb.2015.04.007openalex-snapshot
Daucosterol protects neurons against oxygen–glucose deprivation/reperfusion-mediated injury by activating IGF1 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.leukres.2024.107547openalex-snapshot
Combining the novel FLT3 and MERTK dual inhibitor MRX-2843 with venetoclax results in promising antileukemic activity against FLT3-ITD AML
inferred← citeshttps://doi.org/10.1016/j.mad.2016.06.008openalex-snapshot
Parkin loss-of-function pathology: Premature neuronal senescence induced by high levels of reactive oxygen species?
inferred← citeshttps://doi.org/10.1016/j.mito.2013.01.004openalex-snapshot
The N-terminal helix of Bcl-xL targets mitochondria
inferred← citeshttps://doi.org/10.1016/j.molcel.2012.12.026openalex-snapshot
The Tangled Circuitry of Metabolism and Apoptosis
inferred← citeshttps://doi.org/10.1016/j.molcel.2014.06.001openalex-snapshot
Bcl-2 Family Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent Mitophagy
inferred← citeshttps://doi.org/10.1016/j.molcel.2016.02.019openalex-snapshot
Mitochondria—Judges and Executioners of Cell Death Sentences
inferred← citeshttps://doi.org/10.1016/j.molcel.2018.02.005openalex-snapshot
Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD
inferred← citeshttps://doi.org/10.1016/j.molcel.2024.02.035openalex-snapshot
Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
inferred← citeshttps://doi.org/10.1016/j.molmed.2019.08.009openalex-snapshot
MCL1 as a Therapeutic Target in Parkinson's Disease?
inferred← citeshttps://doi.org/10.1016/j.nbt.2018.02.008openalex-snapshot
Non-immunoglobulin scaffold proteins: Precision tools for studying protein-protein interactions in cancer
inferred← citeshttps://doi.org/10.1016/j.neuint.2017.04.009openalex-snapshot
Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2018.10.009openalex-snapshot
Targeting Mcl-1 and other Bcl-2 family member proteins in cancer therapy
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2021.107943openalex-snapshot
The interplay between apoptosis and cellular senescence: Bcl-2 family proteins as targets for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.stemcr.2018.01.005openalex-snapshot
A Non-apoptotic Function of MCL-1 in Promoting Pluripotency and Modulating Mitochondrial Dynamics in Stem Cells
inferred← citeshttps://doi.org/10.1016/j.tcb.2012.08.011openalex-snapshot
Delving deeper: MCL-1's contributions to normal and cancer biology
inferred← citeshttps://doi.org/10.1016/j.tcb.2012.09.007openalex-snapshot
A ROS rheostat for cell fate regulation
inferred← citeshttps://doi.org/10.1016/j.tcb.2012.10.010openalex-snapshot
Evolution of Bcl-2 homology motifs: homology versus homoplasy
inferred← citeshttps://doi.org/10.1016/j.tcb.2014.04.001openalex-snapshot
Surviving change: the metabolic journey of hematopoietic stem cells
inferred← citeshttps://doi.org/10.1016/j.tcb.2019.03.004openalex-snapshot
Molecular Comprehension of Mcl-1: From Gene Structure to Cancer Therapy
inferred← citeshttps://doi.org/10.1016/j.tcb.2020.03.004openalex-snapshot
Noncanonical Cell Fate Regulation by Bcl-2 Proteins
inferred← citeshttps://doi.org/10.1016/j.tem.2015.02.004openalex-snapshot
Regulation of mitochondrial nutrient and energy metabolism by BCL-2 family proteins
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2016.03.027openalex-snapshot
Effect of heat stress on the survival and development of in vitro cultured bovine preantral follicles and on in vitro maturation of cumulus–oocyte complex
inferred← citeshttps://doi.org/10.1016/j.tibs.2016.01.001openalex-snapshot
Mitochondrial Cristae: Where Beauty Meets Functionality
inferred← citeshttps://doi.org/10.1016/j.tips.2020.09.004openalex-snapshot
BH3 Mimetics in AML Therapy: Death and Beyond?
inferred← citeshttps://doi.org/10.1016/j.toxrep.2026.102290openalex-snapshot
Lycopene supplementation during pregnancy and lactation attenuates thermally oxidized cooking oil-induced hepatic and cerebral damage in rat offspring: A comprehensive histomorphometric and molecular analysis
inferred← citeshttps://doi.org/10.1016/j.tranon.2014.12.004openalex-snapshot
Targeting Mcl-1 for Radiosensitization of Pancreatic Cancers
inferred← citeshttps://doi.org/10.1016/j.virol.2016.01.008openalex-snapshot
Mcl-1 regulates effector and memory CD8 T-cell differentiation during acute viral infection
inferred← citeshttps://doi.org/10.1016/j.yexcr.2015.04.016openalex-snapshot
ABT737 enhances cholangiocarcinoma sensitivity to cisplatin through regulation of mitochondrial dynamics
inferred← citeshttps://doi.org/10.1016/j.yexcr.2021.112549openalex-snapshot
Mitochondrial integration and ovarian cancer chemotherapy resistance
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2020.07.009openalex-snapshot
Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c00355openalex-snapshot
Platinum-Based Mcl-1 Inhibitor Targeting Mitochondria Achieves Enhanced Antitumor Activity as a Single Agent or in Combination with ABT-199
inferred← citeshttps://doi.org/10.1021/acsnano.6b04155openalex-snapshot
Viral/Nonviral Chimeric Nanoparticles To Synergistically Suppress Leukemia Proliferation via Simultaneous Gene Transduction and Silencing
inferred← citeshttps://doi.org/10.1038/bjc.2016.111openalex-snapshot
Targeting cell death signalling in cancer: minimising ‘Collateral damage’
inferred← citeshttps://doi.org/10.1038/cdd.2013.25openalex-snapshot
Mcl-1 antagonizes Bax/Bak to promote effector CD4+ and CD8+ T-cell responses
inferred← citeshttps://doi.org/10.1038/cdd.2013.79openalex-snapshot
Evaluation and critical assessment of putative MCL-1 inhibitors
inferred← citeshttps://doi.org/10.1038/cdd.2014.194openalex-snapshot
CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation
inferred← citeshttps://doi.org/10.1038/cdd.2016.125openalex-snapshot
Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice
inferred← citeshttps://doi.org/10.1038/cdd.2016.20openalex-snapshot
Endothelial cell survival during angiogenesis requires the pro-survival protein MCL1
inferred← citeshttps://doi.org/10.1038/cdd.2016.60openalex-snapshot
PTBP1 modulation of MCL1 expression regulates cellular apoptosis induced by antitubulin chemotherapeutics
inferred← citeshttps://doi.org/10.1038/cdd.2017.154openalex-snapshot
BH3 mimetics efficiently induce apoptosis in mouse basophils and mast cells
inferred← citeshttps://doi.org/10.1038/cdd.2017.161openalex-snapshot
The BCL-2 arbiters of apoptosis and their growing role as cancer targets
inferred← citeshttps://doi.org/10.1038/cdd.2017.168openalex-snapshot
Loss of BIM increases mitochondrial oxygen consumption and lipid oxidation, reduces adiposity and improves insulin sensitivity in mice
inferred← citeshttps://doi.org/10.1038/cdd.2017.183openalex-snapshot
Why do BCL-2 inhibitors work and where should we use them in the clinic?
inferred← citeshttps://doi.org/10.1038/cdd.2017.22openalex-snapshot
Non-apoptotic functions of BCL-2 family proteins
inferred← citeshttps://doi.org/10.1038/cddis.2013.436openalex-snapshot
Structural biology of the Bcl-2 family and its mimicry by viral proteins
inferred← citeshttps://doi.org/10.1038/cddis.2014.419openalex-snapshot
Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2+ uptake and reactive oxygen species generation
inferred← citeshttps://doi.org/10.1038/cddis.2014.561openalex-snapshot
Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)
inferred← citeshttps://doi.org/10.1038/cddis.2015.95openalex-snapshot
Mcl-1 is a key regulator of the ovarian reserve
inferred← citeshttps://doi.org/10.1038/cddis.2017.273openalex-snapshot
Loss of the novel mitochondrial protein FAM210B promotes metastasis via PDK4-dependent metabolic reprogramming
inferred← citeshttps://doi.org/10.1038/cr.2017.155openalex-snapshot
Mitochondrial metabolism and cancer
inferred← citeshttps://doi.org/10.1038/embor.2013.20openalex-snapshot
Programming cancer cells for high expression levels of Mcl1
inferred← citeshttps://doi.org/10.1038/leu.2016.213openalex-snapshot
Survival control of malignant lymphocytes by anti-apoptotic MCL-1
inferred← citeshttps://doi.org/10.1038/nature19830openalex-snapshot
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
inferred← citeshttps://doi.org/10.1038/ncb3616openalex-snapshot
Extra-mitochondrial prosurvival BCL-2 proteins regulate gene transcription by inhibiting the SUFU tumour suppressor
inferred← citeshttps://doi.org/10.1038/ncomms5539openalex-snapshot
Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells
inferred← citeshttps://doi.org/10.1038/ncomms6637openalex-snapshot
Beclin 1 restrains tumorigenesis through Mcl-1 destabilization in an autophagy-independent reciprocal manner
inferred← citeshttps://doi.org/10.1038/nrm3722openalex-snapshot
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
inferred← citeshttps://doi.org/10.1038/onc.2012.348openalex-snapshot
Central roles of apoptotic proteins in mitochondrial function
inferred← citeshttps://doi.org/10.1038/onc.2014.96openalex-snapshot
Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition
inferred← citeshttps://doi.org/10.1038/s41375-023-01946-5openalex-snapshot
MCL1 regulates AML cells metabolism via direct interaction with HK2. Metabolic signature at onset predicts overall survival in AMLs’ patients
inferred← citeshttps://doi.org/10.1038/s41375-025-02694-4openalex-snapshot
Superoxide-mediated phosphorylation and stabilization of Mcl-1 by AKT underlie venetoclax resistance in hematologic malignancies
inferred← citeshttps://doi.org/10.1038/s41375-026-02883-9openalex-snapshot
A STAT3 degrader demonstrates efficacy in venetoclax resistant acute myeloid leukemia
inferred← citeshttps://doi.org/10.1038/s41389-026-00632-2openalex-snapshot
Anti-apoptotic BCL-2 family proteins: from regulatory networks to therapeutic targeting
inferred← citeshttps://doi.org/10.1038/s41392-021-00870-3openalex-snapshot
Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia
inferred← citeshttps://doi.org/10.1038/s41392-023-01503-7openalex-snapshot
The mitophagy pathway and its implications in human diseases
inferred← citeshttps://doi.org/10.1038/s41413-018-0028-5openalex-snapshot
Mandible exosomal ssc-mir-133b regulates tooth development in miniature swine via endogenous apoptosis
inferred← citeshttps://doi.org/10.1038/s41417-026-01016-9openalex-snapshot
Gracillin overcomes osimertinib resistance in NSCLC via dual inhibition of EGFR and Mcl-1
inferred← citeshttps://doi.org/10.1038/s41418-017-0012-4openalex-snapshot
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
inferred← citeshttps://doi.org/10.1038/s41418-019-0327-4openalex-snapshot
Bok regulates mitochondrial fusion and morphology
inferred← citeshttps://doi.org/10.1038/s41418-020-00683-xopenalex-snapshot
BCL(X)L and BCL2 increase the metabolic fitness of breast cancer cells: a single-cell imaging study
inferred← citeshttps://doi.org/10.1038/s41418-020-0517-0openalex-snapshot
MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex
inferred← citeshttps://doi.org/10.1038/s41418-020-0585-1openalex-snapshot
MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3+ regulatory T cells
inferred← citeshttps://doi.org/10.1038/s41418-021-00773-4openalex-snapshot
Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function
inferred← citeshttps://doi.org/10.1038/s41418-023-01153-wopenalex-snapshot
Apoptotic cell death in disease—Current understanding of the NCCD 2023
inferred← citeshttps://doi.org/10.1038/s41418-023-01245-7openalex-snapshot
Non-canonical BIM-regulated energy metabolism determines drug-induced liver necrosis
inferred← citeshttps://doi.org/10.1038/s41418-025-01481-zopenalex-snapshot
The BCL-2 protein family: from discovery to drug development
inferred← citeshttps://doi.org/10.1038/s41419-017-0035-2openalex-snapshot
MCL-1 is a prognostic indicator and drug target in breast cancer
inferred← citeshttps://doi.org/10.1038/s41419-017-0039-yopenalex-snapshot
Systems modeling accurately predicts responses to genotoxic agents and their synergism with BCL-2 inhibitors in triple negative breast cancer cells
inferred← citeshttps://doi.org/10.1038/s41419-018-0413-4openalex-snapshot
Pan-class I PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53
inferred← citeshttps://doi.org/10.1038/s41419-019-2150-8openalex-snapshot
Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck
inferred← citeshttps://doi.org/10.1038/s41419-020-02760-yopenalex-snapshot
Ubiquitination and deubiquitination of MCL1 in cancer: deciphering chemoresistance mechanisms and providing potential therapeutic options
inferred← citeshttps://doi.org/10.1038/s41419-020-02944-6openalex-snapshot
BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models
inferred← citeshttps://doi.org/10.1038/s41419-020-2498-9openalex-snapshot
MCL-1Matrix maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions
inferred← citeshttps://doi.org/10.1038/s41419-021-04334-yopenalex-snapshot
MCL1 nuclear translocation induces chemoresistance in colorectal carcinoma
inferred← citeshttps://doi.org/10.1038/s41419-023-05559-9openalex-snapshot
EVA1A regulates hematopoietic stem cell regeneration via ER-mitochondria mediated apoptosis
inferred← citeshttps://doi.org/10.1038/s41419-023-06233-wopenalex-snapshot
Potentiation of apoptosis in drug-resistant mantle cell lymphoma cells by MCL-1 inhibitor involves downregulation of inhibitor of apoptosis proteins
inferred← citeshttps://doi.org/10.1038/s41420-018-0104-zopenalex-snapshot
Misoprostol regulates Bnip3 repression and alternative splicing to control cellular calcium homeostasis during hypoxic stress
inferred← citeshttps://doi.org/10.1038/s41420-019-0199-xopenalex-snapshot
DRP-1 functions independently of mitochondrial structural perturbations to facilitate BH3 mimetic-mediated apoptosis
inferred← citeshttps://doi.org/10.1038/s41422-025-01203-7openalex-snapshot
Mitophagy in the pathogenesis and management of disease
inferred← citeshttps://doi.org/10.1038/s41467-017-02693-9openalex-snapshot
Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors
inferred← citeshttps://doi.org/10.1038/s41467-024-45609-0openalex-snapshot
Structural optimization of siRNA conjugates for albumin binding achieves effective MCL1-directed cancer therapy
inferred← citeshttps://doi.org/10.1038/s41467-025-58150-5openalex-snapshot
MCL‑1 safeguards activated hair follicle stem cells to enable adult hair regeneration
inferred← citeshttps://doi.org/10.1038/s41467-025-66831-4openalex-snapshot
MCL1 modulates mTORC1 signaling to promote bioenergetics and tumorigenesis
inferred← citeshttps://doi.org/10.1038/s41580-018-0089-8openalex-snapshot
Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins
inferred← citeshttps://doi.org/10.1038/s41598-018-25802-0openalex-snapshot
Inhibition of Bcl-2/Bcl-xL and c-MET causes synthetic lethality in model systems of glioblastoma
inferred← citeshttps://doi.org/10.1038/s41598-019-43609-5openalex-snapshot
Hemidesmus indicus induces apoptosis via proteasome inhibition and generation of reactive oxygen species
inferred← citeshttps://doi.org/10.1038/s41598-020-67755-3openalex-snapshot
Bax and Bak jointly control survival and dampen the early unfolded protein response in pancreatic β-cells under glucolipotoxic stress
inferred← citeshttps://doi.org/10.1038/s41598-026-42518-8openalex-snapshot
Fingolimod normalizes metabolic signatures associated with synaptic plasticity and memory in APP/PS1 model: Sphingosine-1-phosphate receptor a therapeutic target for Alzheimer’s
inferred← citeshttps://doi.org/10.1038/s42003-021-02564-6openalex-snapshot
The multiple mechanisms of MCL1 in the regulation of cell fate
inferred← citeshttps://doi.org/10.1038/s43018-020-00126-zopenalex-snapshot
Fatty acid metabolism underlies venetoclax resistance in acute myeloid leukemia stem cells
inferred← citeshttps://doi.org/10.1038/s43018-024-00814-0openalex-snapshot
BRD-810 is a highly selective MCL1 inhibitor with optimized in vivo clearance and robust efficacy in solid and hematological tumor models
inferred← citeshttps://doi.org/10.1038/srep23802openalex-snapshot
p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.
inferred← citeshttps://doi.org/10.1038/srep38219openalex-snapshot
Energy metabolism regulated by HDAC inhibitor attenuates cardiac injury in hemorrhagic rat model
inferred← citeshttps://doi.org/10.1039/d1tb01143jopenalex-snapshot
ROS-responsive organosilica nanocarrier for the targeted delivery of metformin against cancer with the synergistic effect of hypoglycemia
inferred← citeshttps://doi.org/10.1042/cs20190960openalex-snapshot
Mitochondrial dynamic modulation exerts cardiometabolic protection in obese insulin-resistant rats
inferred← citeshttps://doi.org/10.1051/jbio/2016003openalex-snapshot
Du duel au pluriel : réflexions sur les protéines régulatrices d’apoptose de la famille BCL-2 et sur la mort cellulaire
inferred← citeshttps://doi.org/10.1073/pnas.1321259110openalex-snapshot
Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis
inferred← citeshttps://doi.org/10.1073/pnas.1707292114openalex-snapshot
Small mitochondrial Arf (smArf) protein corrects p53-independent developmental defects of Arf tumor suppressor-deficient mice
inferred← citeshttps://doi.org/10.1074/jbc.m115.663898openalex-snapshot
Structure-Function Analysis of the Mcl-1 Protein Identifies a Novel Senescence-regulating Domain
inferred← citeshttps://doi.org/10.1080/07391102.2018.1508371openalex-snapshot
Molecular dynamic simulations on an inhibitor of anti-apoptotic Bcl-2 proteins for insights into its interaction mechanism for anti-cancer activity
inferred← citeshttps://doi.org/10.1080/10428194.2023.2200876openalex-snapshot
AMG176, an MCL-1 inhibitor, is active in pre-clinical models of aggressive B-cell lymphomas
inferred← citeshttps://doi.org/10.1080/10799893.2025.2503393openalex-snapshot
Regulation of elevated expression of Mcl-1 in hepatocellular carcinoma – a review
inferred← citeshttps://doi.org/10.1080/13543776.2016.1240786openalex-snapshot
Substituted indole Mcl-1 inhibitors: a patent evaluation (WO2015148854A1)
inferred← citeshttps://doi.org/10.1080/15384101.2018.1464851openalex-snapshot
The established and the predicted roles of dynein light chain in the regulation of mitochondrial apoptosis
inferred← citeshttps://doi.org/10.1080/15384101.2025.2484868openalex-snapshot
Non-canonical functions of BCL-2 family members in energy metabolism and necrotic cell death regulation
inferred← citeshttps://doi.org/10.1080/15548627.2017.1407887openalex-snapshot
AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells
inferred← citeshttps://doi.org/10.1080/17474086.2023.2174521openalex-snapshot
An overview of novel therapies in advanced clinical testing for acute myeloid leukemia
inferred← citeshttps://doi.org/10.1080/19336918.2017.1393591openalex-snapshot
Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion
inferred← citeshttps://doi.org/10.1080/21691401.2019.1596944openalex-snapshot
LncRNA ANRIL protects against oxygen and glucose deprivation (OGD)-induced injury in PC-12 cells: potential role in ischaemic stroke
inferred← citeshttps://doi.org/10.1089/ars.2012.4905openalex-snapshot
Regulation of the Intrinsic Apoptosis Pathway by Reactive Oxygen Species
showing the first 200 of 404 · page through all 404
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.