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Stiffening hydrogels to probe short- and long-term cellular responses to dynamic mechanics
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Novel thermally reversible hydrogel as detachable cell culture substrate
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Swelling‐Induced Surface Patterns in Hydrogels with Gradient Crosslinking Density
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Dynamic Hydrogels: Switching of 3D Microenvironments Using Two‐Component Naturally Derived Extracellular Matrices
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Hyaluronic Acid Hydrogels for Biomedical Applications
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Electron microscopy of developing cardiac muscle in chick embryos
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Guiding cell migration in 3D: A collagen matrix with graded directional stiffness
inferredcites →https://doi.org/10.1002/jmor.1050880104openalex-snapshot
A series of normal stages in the development of the chick embryo
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Close dependence of fibroblast proliferation on collagen scaffold matrix stiffness
inferredcites →https://doi.org/10.1016/j.biomaterials.2009.10.050openalex-snapshot
The relationship between fibroblast growth and the dynamic stiffnesses of a DNA crosslinked hydrogel
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The control of stem cell morphology and differentiation by hydrogel surface wrinkles
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Patterning network structure to spatially control cellular remodeling and stem cell fate within 3-dimensional hydrogels
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Dual growth factor delivery and controlled scaffold degradation enhance in vivo bone formation by transplanted bone marrow stromal cells
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Matrix Elasticity Directs Stem Cell Lineage Specification
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Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
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Cell Movement Is Guided by the Rigidity of the Substrate
inferredcites →https://doi.org/10.1016/s0006-3495(99)77386-8openalex-snapshot
Stresses at the Cell-to-Substrate Interface during Locomotion of Fibroblasts
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Cell Shape, Cytoskeletal Tension, and RhoA Regulate Stem Cell Lineage Commitment
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Controlled Degradation and Mechanical Behavior of Photopolymerized Hyaluronic Acid Networks
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Quantitative Evaluation of Mechanosensing of Cells on Dynamically Tunable Hydrogels
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A DNA-fuelled molecular machine made of DNA
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Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells
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Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms
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Local force and geometry sensing regulate cell functions
inferredcites →https://doi.org/10.1039/b820385gopenalex-snapshot
Sequential crosslinking to control cellular spreading in 3-dimensional hydrogels
inferredcites →https://doi.org/10.1039/b916933dopenalex-snapshot
Spatially controlled hydrogel mechanics to modulate stem cell interactions
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Logic swelling response of DNA–polymer hybrid hydrogel
inferredcites →https://doi.org/10.1073/pnas.0606150103openalex-snapshot
Viscoelastic properties of individual glial cells and neurons in the CNS
inferredcites →https://doi.org/10.1073/pnas.0903269107openalex-snapshot
Geometric cues for directing the differentiation of mesenchymal stem cells
inferredcites →https://doi.org/10.1073/pnas.1007940107openalex-snapshot
Real-time single-cell response to stiffness
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Myotubes differentiate optimally on substrates with tissue-like stiffness
inferredcites →https://doi.org/10.1083/jcb.200704042openalex-snapshot
Myofibroblast contraction activates latent TGF-β1 from the extracellular matrix
inferredcites →https://doi.org/10.1083/jcb.201004082openalex-snapshot
Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression
inferredcites →https://doi.org/10.1089/10763270152436517openalex-snapshot
Thermo-Responsive Culture Dishes Allow the Intact Harvest of Multilayered Keratinocyte Sheets without Dispase by Reducing Temperature
inferredcites →https://doi.org/10.1089/neu.2006.0169openalex-snapshot
Mechanical Heterogeneity of the Rat Hippocampus Measured by Atomic Force Microscope Indentation
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Review. Hyaluronan: A Powerful Tissue Engineering Tool
inferredcites →https://doi.org/10.1089/ten.tea.2007.0388openalex-snapshot
Bone Marrow-Derived Human Mesenchymal Stem Cells Become Quiescent on Soft Substrates but Remain Responsive to Chemical or Mechanical Stimuli
inferredcites →https://doi.org/10.1089/ten.tea.2009.0574openalex-snapshot
Effect of Dynamic Stiffness of the Substrates on Neurite Outgrowth by Using a DNA-Crosslinked Hydrogel
inferredcites →https://doi.org/10.1115/1.1645529openalex-snapshot
Mechanical Properties of a Reversible, DNA-Crosslinked Polyacrylamide Hydrogel
inferredcites →https://doi.org/10.1126/science.1116995openalex-snapshot
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
inferredcites →https://doi.org/10.1126/science.284.5411.143openalex-snapshot
Multilineage Potential of Adult Human Mesenchymal Stem Cells
inferredcites →https://doi.org/10.1126/science.7684161openalex-snapshot
Mechanotransduction Across the Cell Surface and Through the Cytoskeleton
inferredcites →https://doi.org/10.1152/ajpgi.00032.2007openalex-snapshot
Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis
inferredcites →https://doi.org/10.1152/ajpheart.01017.2005openalex-snapshot
Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance
inferredcites →https://doi.org/10.1152/physrev.00012.2007openalex-snapshot
Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function
inferredcites →https://doi.org/10.1161/01.cir.94.1.94openalex-snapshot
Rate of Collagen Deposition During Healing and Ventricular Remodeling After Myocardial Infarction in Rat and Dog Models
inferredcites →https://doi.org/10.1182/blood-2006-12-063412openalex-snapshot
Potential risks of bone marrow cell transplantation into infarcted hearts
inferredcites →https://doi.org/10.1186/1471-2164-8-15openalex-snapshot
Phylogenetic distribution of translational GTPases in bacteria
inferredcites →https://doi.org/10.1186/1471-2164-8-70openalex-snapshot
Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation
inferredcites →https://doi.org/10.1529/biophysj.104.054320openalex-snapshot
The Dynamics and Mechanics of Endothelial Cell Spreading
inferredcites →https://doi.org/10.1529/biophysj.108.132217openalex-snapshot
Substrate Modulus Directs Neural Stem Cell Behavior
inferredcites →https://doi.org/10.1529/biophysj.108.134627openalex-snapshot
Spatiotemporal Analysis of Cell Response to a Rigidity Gradient: A Quantitative Study Using Multiple Optical Tweezers
inferredcites →https://doi.org/10.1557/jmr.2005.0186openalex-snapshot
Inducing Reversible Stiffness Changes in DNA-crosslinked Gels
inferredcites →https://doi.org/10.1634/stemcells.2008-0432openalex-snapshot
Emergence of Patterned Stem Cell Differentiation Within Multicellular Structures
inferredcites →https://doi.org/10.3233/bir-2008-0487openalex-snapshot
Phenotypic analysis of cell surface markers and gene expression of human mesenchymal stem cells and chondrocytes during monolayer expansion
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1002/anie.202314738openalex-snapshot
Dynamic Exchange in 3D Cell Culture Hydrogels Based on Crosslinking of Cyclic Thiosulfinates
inferred← citeshttps://doi.org/10.1002/app.47212openalex-snapshot
Bioinspired glycosaminoglycan hydrogels via click chemistry for 3D dynamic cell encapsulation
inferred← citeshttps://doi.org/10.1002/biot.201600394openalex-snapshot
Development of hydrogels for regenerative engineering
inferred← citeshttps://doi.org/10.1002/bit.26075openalex-snapshot
Modulation of human mesenchymal and pluripotent stem cell behavior using biophysical and biochemical cues: A review
inferred← citeshttps://doi.org/10.1002/cbin.10325openalex-snapshot
Mechanosensing of cells in 3D gel matrices based on natural and synthetic materials
inferred← citeshttps://doi.org/10.1002/cbin.11091openalex-snapshot
Smart hydrogels with high tunability of stiffness as a biomimetic cell carrier
inferred← citeshttps://doi.org/10.1002/cbin.12151openalex-snapshot
Assessment of human embryonic stem cells differentiation into definitive endoderm lineage on the soft substrates
inferred← citeshttps://doi.org/10.1002/cm.21129openalex-snapshot
Resiliency of the plasma membrane and actin cortex to large‐scale deformation
inferred← citeshttps://doi.org/10.1002/cphy.c210032openalex-snapshot
Extracellular Matrix Stiffness in Lung Health and Disease
inferred← citeshttps://doi.org/10.1002/cptc.201700038openalex-snapshot
Rational Hydrogel Formulation Leads to Reversible and Enhanced Photocontrolled Rigidity
inferred← citeshttps://doi.org/10.1002/ctm2.1244openalex-snapshot
Boolean logic in synthetic biology and biomaterials: Towards living materials in mammalian cell therapeutics
inferred← citeshttps://doi.org/10.1002/dvdy.24379openalex-snapshot
Extracellular matrix bioscaffolds in tissue remodeling and morphogenesis
inferred← citeshttps://doi.org/10.1002/gch2.202100094openalex-snapshot
Biophysics Role and Biomimetic Culture Systems of ECM Stiffness in Cancer EMT
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2022.tb00222.xopenalex-snapshot
Extracellular Matrix Stiffness in Lung Health and Disease
inferred← citeshttps://doi.org/10.1002/jbm.a.35850openalex-snapshot
Elastic, silk-cardiac extracellular matrix hydrogels exhibit time-dependent stiffening that modulates cardiac fibroblast response
inferred← citeshttps://doi.org/10.1002/jbm.a.37125openalex-snapshot
An in vitro assessment of the response of THP‐1 macrophages to varying stiffness of a glycol‐chitosan hydrogel for vocal fold tissue engineering applications
inferred← citeshttps://doi.org/10.1002/jbm.a.37253openalex-snapshot
Investigation of human adipose‐derived stem‐cell behavior using a cell‐instructive polydopamine‐coated gelatin–alginate hydrogel
inferred← citeshttps://doi.org/10.1002/jbm.a.37273openalex-snapshot
Hybrid adipose graft materials synthesized from chemically modified adipose extracellular matrix
inferred← citeshttps://doi.org/10.1002/jcp.26193openalex-snapshot
Regulating osteogenesis and adipogenesis in adipose‐derived stem cells by controlling underlying substrate stiffness
inferred← citeshttps://doi.org/10.1002/jcp.29678openalex-snapshot
Matrix stiffness controls cardiac fibroblast activation through regulating YAP via AT 1 R
inferred← citeshttps://doi.org/10.1002/mabi.201600280openalex-snapshot
Tunable Crosslinked Cell-Derived Extracellular Matrix Guides Cell Fate
inferred← citeshttps://doi.org/10.1002/mabi.201700158openalex-snapshot
Covalent Incorporation of Heparin Improves Chondrogenesis in Photocurable Gelatin‐Methacryloyl Hydrogels
inferred← citeshttps://doi.org/10.1002/mabi.202000307openalex-snapshot
Hydrogel‐Forming Microneedles: Current Advancements and Future Trends
inferred← citeshttps://doi.org/10.1002/mabi.202200425openalex-snapshot
Self‐Forming Norbornene‐Tetrazine Hydrogels with Independently Tunable Properties
inferred← citeshttps://doi.org/10.1002/mabi.202300110openalex-snapshot
Serial Passaging Affects Stromal Cell Mechanosensitivity on Hyaluronic Acid Hydrogels
inferred← citeshttps://doi.org/10.1002/mabi.202500400openalex-snapshot
Dynamic Gelatin Hydrogels Crosslinked by Dithiolane‐Norbornene Click Chemistry
inferred← citeshttps://doi.org/10.1002/mame.202100623openalex-snapshot
Gamma Radiation Induced Contraction of Alkyne Modified Polymer Hydrogels
inferred← citeshttps://doi.org/10.1002/mame.202500019openalex-snapshot
Bioelectronic Hydrogels: Exemplifying the Synergy Between Biopolymers and Conjugated Polymers
inferred← citeshttps://doi.org/10.1002/marc.201600570openalex-snapshot
Hydrogel with Orthogonal Reactive Units: 2D and 3D Cross‐Linking Modulation
inferred← citeshttps://doi.org/10.1002/marc.202400177openalex-snapshot
Gradually Self‐Strengthen DNA Supramolecular Hydrogels
inferred← citeshttps://doi.org/10.1002/marc.202500909openalex-snapshot
Toward Dynamic Liquid Cell Scaffold: Photoreversible Ion Gels Exhibiting Light‐Induced Sol‐Gel Transitions
inferred← citeshttps://doi.org/10.1002/marc.70354openalex-snapshot
Dynamic Biomaterial: A Platform for Biomedical Applications With Multiple Preparation Strategies
inferred← citeshttps://doi.org/10.1002/marc.70416openalex-snapshot
Regulating the Dynamic Properties of Knoevenagel Condensation Cross‐Linked Hydrogels via Thia‐Michael Addition Reaction
inferred← citeshttps://doi.org/10.1002/masy.201200105openalex-snapshot
Fabrication and Characterization of Novel High Modulus, Two‐ S tage Reactive Thiol‐ A crylate Composite Polymer Systems
inferred← citeshttps://doi.org/10.1002/smll.202106649openalex-snapshot
Self‐Organized Spatiotemporal Mineralization of Hydrogel: A Simulant of Osteon
inferred← citeshttps://doi.org/10.1002/stem.2489openalex-snapshot
Dynamics of Mechanosensitive Neural Stem Cell Differentiation
inferred← citeshttps://doi.org/10.1002/stem.2502openalex-snapshot
Concise Review: Organ Engineering: Design, Technology, and Integration
inferred← citeshttps://doi.org/10.1002/stem.3105openalex-snapshot
Tunable hydrogels for mesenchymal stem cell delivery: Integrin-induced transcriptome alterations and hydrogel optimization for human wound healing
inferred← citeshttps://doi.org/10.1007/8415_2013_172openalex-snapshot
Extracellular Matrix Remodeling and Mechanical Stresses as Modulators of Adipose Tissue Metabolism and Inflammation
inferred← citeshttps://doi.org/10.1007/978-1-0716-0755-8_15openalex-snapshot
Synthesis of a Light-Controlled Phytochrome-Based Extracellular Matrix with Reversibly Adjustable Mechanical Properties
inferred← citeshttps://doi.org/10.1007/978-1-4471-4372-7_34openalex-snapshot
Engineering of Photomanipulatable Hydrogels for Translational Medicine
inferred← citeshttps://doi.org/10.1007/978-3-030-23906-0_1openalex-snapshot
3D Bioprinting Technologies
inferred← citeshttps://doi.org/10.1007/978-3-031-26625-6_9openalex-snapshot
Engineering Dynamic 3D Models of Lung
inferred← citeshttps://doi.org/10.1007/978-3-032-30294-6_5openalex-snapshot
Translating Physical Cues into Cellular Responses: Material-Mediated Strategies in Biofabrication
inferred← citeshttps://doi.org/10.1007/978-3-319-05074-4_2openalex-snapshot
Physical and Engineering Principles in Stem Cell Research
inferred← citeshttps://doi.org/10.1007/978-3-319-17930-8_3openalex-snapshot
Mimicking the Microenvironment
inferred← citeshttps://doi.org/10.1007/978-3-319-20726-1_2openalex-snapshot
Photochemical Patterning of Cellular Microenvironments
inferred← citeshttps://doi.org/10.1007/978-3-319-21702-4_3openalex-snapshot
Emerging Engineering Strategies for Studying the Stem Cell Niche
inferred← citeshttps://doi.org/10.1007/978-3-319-25322-0_3openalex-snapshot
Polysaccharide-Based Hydrogels as Biomaterials
inferred← citeshttps://doi.org/10.1007/978-3-319-89542-0_1openalex-snapshot
Nanotechnology for Orthopedic Applications: From Manufacturing Processes to Clinical Applications
inferred← citeshttps://doi.org/10.1007/978-4-431-55139-3_1openalex-snapshot
Recent Advances in 3D Tissue Models
inferred← citeshttps://doi.org/10.1007/978-981-16-5374-2_6openalex-snapshot
Hydrogel Scaffolds Based on Alginate, Gelatin, and 2-Hydroxyethyl Methacrylate for Tissue Regeneration
inferred← citeshttps://doi.org/10.1007/978-981-99-0846-2_57-1openalex-snapshot
Targeting Mechanobiology of Stem Cells Via Biomaterials for Regenerative Medicine Approaches
inferred← citeshttps://doi.org/10.1007/978-981-99-6948-7_3openalex-snapshot
Versatile Hydrogels in Regenerative Medicine
inferred← citeshttps://doi.org/10.1007/978-981-99-7119-0_57openalex-snapshot
Targeting Mechanobiology of Stem Cells via Biomaterials for Regenerative Medicine Approaches
inferred← citeshttps://doi.org/10.1007/s00018-018-2830-zopenalex-snapshot
Why the impact of mechanical stimuli on stem cells remains a challenge
inferred← citeshttps://doi.org/10.1007/s00018-020-03600-0openalex-snapshot
Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses
inferred← citeshttps://doi.org/10.1007/s00441-012-1531-4openalex-snapshot
Mechanical cues in cellular signalling and communication
inferred← citeshttps://doi.org/10.1007/s10295-018-2027-3openalex-snapshot
Bottom-up approaches in synthetic biology and biomaterials for tissue engineering applications
inferred← citeshttps://doi.org/10.1007/s10409-019-00845-2openalex-snapshot
Effects of hypoxia on the biological behavior of MSCs seeded in demineralized bone scaffolds with different stiffness
inferred← citeshttps://doi.org/10.1007/s10439-014-1104-7openalex-snapshot
A Perspective on the Clinical Translation of Scaffolds for Tissue Engineering
inferred← citeshttps://doi.org/10.1007/s10544-016-0110-yopenalex-snapshot
Precise positioning of cancerous cells on PDMS substrates with gradients of elasticity
inferred← citeshttps://doi.org/10.1007/s11426-023-1566-xopenalex-snapshot
Host defense peptide-mimicking peptide polymer-based antibacterial hydrogel enables efficient healing of MRSA-infected wounds
inferred← citeshttps://doi.org/10.1007/s11427-015-4865-9openalex-snapshot
The role of the microenvironment on the fate of adult stem cells
inferred← citeshttps://doi.org/10.1007/s12274-017-1890-yopenalex-snapshot
Reversible hydrogels with tunable mechanical properties for optically controlling cell migration
inferred← citeshttps://doi.org/10.1007/s12551-018-0466-8openalex-snapshot
Tissue engineering the cancer microenvironment—challenges and opportunities
inferred← citeshttps://doi.org/10.1007/s12551-024-01265-8openalex-snapshot
Hydrogel models of pancreatic adenocarcinoma to study cell mechanosensing
inferred← citeshttps://doi.org/10.1007/s13206-026-00282-xopenalex-snapshot
Spatiotemporal Control of Organoid Biofabrication with Nanoengineered Bioinks
inferred← citeshttps://doi.org/10.1007/s13770-022-00500-1openalex-snapshot
Tailoring Hydrogel Composition and Stiffness to Control Smooth Muscle Cell Differentiation in Bioprinted Constructs
inferred← citeshttps://doi.org/10.1007/s40544-023-0815-xopenalex-snapshot
Nano-frictional mechano-reinforcing porous nanowires scaffolds
inferred← citeshttps://doi.org/10.1007/s40843-019-1184-yopenalex-snapshot
Photoinduced directional domain sliding motion in peptide hydrogels promotes ectodermal differentiation of embryonic stem cells
inferred← citeshttps://doi.org/10.1007/s40883-020-00164-0openalex-snapshot
Hydrogel Properties May Influence Mesenchymal Stem Cell Lineage Progression Through Modulating GAPDH Activity
inferred← citeshttps://doi.org/10.1007/s40883-025-00458-1openalex-snapshot
Growth Factors and Cytokines for Regenerative Medicine: Translational Challenges and Emerging Engineering Solutions
inferred← citeshttps://doi.org/10.1007/s44164-025-00103-9openalex-snapshot
Decellularized extracellular matrix for gastrointestinal organoid culture: a comprehensive review
inferred← citeshttps://doi.org/10.1016/b978-0-08-055294-1.00067-2openalex-snapshot
Materials as Artificial Stem Cell Microenvironments
inferred← citeshttps://doi.org/10.1016/b978-0-08-102937-4.00001-7openalex-snapshot
Dynamic cell instructive platforms
inferred← citeshttps://doi.org/10.1016/b978-0-12-394624-9.00011-7openalex-snapshot
Biomaterials Approaches in Stem Cell Mechanobiology
inferred← citeshttps://doi.org/10.1016/b978-0-12-397157-9.00048-5openalex-snapshot
Multi-Tissue Interface Bioengineering
inferred← citeshttps://doi.org/10.1016/b978-0-12-409547-2.12380-7openalex-snapshot
Use of Stem Cells in Toxicology
inferred← citeshttps://doi.org/10.1016/b978-0-12-803581-8.10150-xopenalex-snapshot
2.9 Materials as Artificial Stem Cell Microenvironments ☆
inferred← citeshttps://doi.org/10.1016/b978-0-12-817827-0.00060-6openalex-snapshot
Engineered microenvironments for cancer study
inferred← citeshttps://doi.org/10.1016/b978-0-323-35321-2.00020-0openalex-snapshot
Engineered Microenvironments for Cancer Study
inferred← citeshttps://doi.org/10.1016/b978-0-323-85671-3.00012-9openalex-snapshot
The fate of stem cells within smart biomaterials and constructs
inferred← citeshttps://doi.org/10.1016/b978-0-323-99892-5.00021-9openalex-snapshot
hiPSC disease modeling with 3D organoids
inferred← citeshttps://doi.org/10.1016/b978-0-443-30151-3.00005-xopenalex-snapshot
Biomaterial-based Platforms for Modeling the Pre-metastatic Niche
inferred← citeshttps://doi.org/10.1016/bs.apha.2017.08.008openalex-snapshot
The Role of Age-Related Intimal Remodeling and Stiffening in Atherosclerosis
inferred← citeshttps://doi.org/10.1016/j.actamat.2012.10.037openalex-snapshot
Hydrogels in healthcare: From static to dynamic material microenvironments
inferred← citeshttps://doi.org/10.1016/j.actbio.2013.03.019openalex-snapshot
In vivo response to dynamic hyaluronic acid hydrogels
inferred← citeshttps://doi.org/10.1016/j.actbio.2014.05.023openalex-snapshot
The effects of varying poly(ethylene glycol) hydrogel crosslinking density and the crosslinking mechanism on protein accumulation in three-dimensional hydrogels
inferred← citeshttps://doi.org/10.1016/j.actbio.2015.04.008openalex-snapshot
Mechanobiology of mesenchymal stem cells: Perspective into mechanical induction of MSC fate
inferred← citeshttps://doi.org/10.1016/j.actbio.2015.09.019openalex-snapshot
Hydrogel arrays formed via differential wettability patterning enable combinatorial screening of stem cell behavior
inferred← citeshttps://doi.org/10.1016/j.actbio.2016.04.031openalex-snapshot
Guiding cell migration with microscale stiffness patterns and undulated surfaces
inferred← citeshttps://doi.org/10.1016/j.actbio.2017.05.044openalex-snapshot
Combinatorial screening of 3D biomaterial properties that promote myofibrogenesis for mesenchymal stromal cell-based heart valve tissue engineering
inferred← citeshttps://doi.org/10.1016/j.actbio.2018.11.011openalex-snapshot
Dynamic control of hydrogel crosslinking via sortase-mediated reversible transpeptidation
inferred← citeshttps://doi.org/10.1016/j.actbio.2018.12.019openalex-snapshot
Cellular responses to thermoresponsive stiffness memory elastomer nanohybrid scaffolds by 3D-TIPS
inferred← citeshttps://doi.org/10.1016/j.actbio.2019.01.052openalex-snapshot
Refined assessment of the impact of cell shape on human mesenchymal stem cell differentiation in 3D contexts
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