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Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
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2 of the 54 references listed on this page are in the Retraction Watch database as retracted (export 2026-10-28): 10.1016/j.cell.2009.03.047 (notice 2015-04-09), 10.1158/0008-5472.can-09-4598 (notice 2018-09-14).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/s12032-010-9515-2openalex-snapshotHigh expression of PD-L1 in lung cancer may contribute to poor prognosis and tumor cells immune escape through suppressing tumor infiltrating dendritic cells maturation
inferredcites →https://doi.org/10.1038/cmi.2010.28openalex-snapshotProgrammed death-1 upregulation is correlated with dysfunction of tumor-infiltrating CD8+ T lymphocytes in human non-small cell lung cancer
inferredcites →https://doi.org/10.1038/ncb1722openalex-snapshotThe miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
inferredcites →https://doi.org/10.1038/nm730openalex-snapshotTumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
inferredcites →https://doi.org/10.1073/pnas.0712237105openalex-snapshotImmunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
inferredcites →https://doi.org/10.1074/jbc.c800074200openalex-snapshotThe miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2
inferredcites →https://doi.org/10.1101/gad.1640608openalex-snapshotThe miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
inferredcites →https://doi.org/10.1126/scitranslmed.3003689openalex-snapshotColocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape
inferredcites →https://doi.org/10.1158/0008-5472.can-09-4598openalex-snapshotGemcitabine Sensitivity Can Be Induced in Pancreatic Cancer Cells through Modulation of miR-200 and miR-21 Expression by Curcumin or Its Analogue CDF
inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-1558openalex-snapshotAn Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance
inferredcites →https://doi.org/10.1172/jci42579openalex-snapshotThe Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200–dependent pathway in mice
inferredcites →https://doi.org/10.1677/erc-10-0148openalex-snapshotThe miR-200 family controls -tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1002/1878-0261.12085openalex-snapshotEMT‐ and MET‐related processes in nonepithelial tumors: importance for disease progression, prognosis, and therapeutic opportunities
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inferred← citeshttps://doi.org/10.1002/ange.202214750openalex-snapshotPD‐L1 Aptamer‐Functionalized Metal–Organic Framework Nanoparticles for Robust Photo‐Immunotherapy against Cancer with Enhanced Safety
inferred← citeshttps://doi.org/10.1002/anie.202214750openalex-snapshotPD‐L1 Aptamer‐Functionalized Metal–Organic Framework Nanoparticles for Robust Photo‐Immunotherapy against Cancer with Enhanced Safety
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inferred← citeshttps://doi.org/10.1002/cbf.4010openalex-snapshotAdenosine increases PD‐L1 expression in mesenchymal stromal cells derived from cervical cancer through its interaction with A2AR/A2BR and the production of TGF‐β1
inferred← citeshttps://doi.org/10.1002/cncr.33135openalex-snapshotFrequency and clinicopathologic associations of DNA mismatch repair protein deficiency in ampullary carcinoma: Routine testing is indicated
inferred← citeshttps://doi.org/10.1002/elsa.202100174openalex-snapshotGlycerol electro‐reforming in alkaline electrolysis cells for the simultaneous production of value‐added chemicals and pure hydrogen – Mini‐review
inferred← citeshttps://doi.org/10.1002/gcc.23216openalex-snapshotPolymorphisms of the PD‐L1 gene 3′‐untranslated region are associated with the expression of PD‐L1 in non‐small cell lung cancer
inferred← citeshttps://doi.org/10.1002/hep.28710openalex-snapshotProgrammed death ligand 1 expression in hepatocellular carcinoma: Relationship With clinical and pathological features
inferred← citeshttps://doi.org/10.1002/hep4.1682openalex-snapshotInhibition of CMTM4 Sensitizes Cholangiocarcinoma and Hepatocellular Carcinoma to T Cell–Mediated Antitumor Immunity Through PD‐L1
inferred← citeshttps://doi.org/10.1002/ijc.34127openalex-snapshotCancer‐associated fibroblasts in nonsmall cell lung cancer: From molecular mechanisms to clinical implications
inferred← citeshttps://doi.org/10.1002/jbt.23719openalex-snapshotChallenges and opportunities for cancer stem cell‐targeted immunotherapies include immune checkpoint inhibitor, cancer stem cell‐dendritic cell vaccine, chimeric antigen receptor immune cells, and modified exosomes
inferred← citeshttps://doi.org/10.1002/jbt.70985openalex-snapshotMAPK12 Upregulates PD‐L1 Expression in Hepatocellular Carcinoma to Induce Immune Suppression Through the PI3K/AKT/mTOR Pathway
inferred← citeshttps://doi.org/10.1002/jcp.29671openalex-snapshotRole of tumor microenvironment in the regulation of PD‐L1: A novel role in resistance to cancer immunotherapy
inferred← citeshttps://doi.org/10.1002/kjm2.12212openalex-snapshotRetracted: Protective effect of hsa‐miR ‐570‐3p targeting CD274 on triple negative breast cancer by blocking PI3K / AKT / mTOR signaling pathway
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inferred← citeshttps://doi.org/10.1007/s00428-021-03266-4openalex-snapshotDesmoplastic reactions and epithelial-mesenchymal transition proteins in stages II and III colorectal cancer: association with and prognostic value for disease-free survival
inferred← citeshttps://doi.org/10.1007/s00438-024-02199-2openalex-snapshotDiscovering the role of microRNAs and exosomal microRNAs in chest and pulmonary diseases: a spotlight on chronic obstructive pulmonary disease
inferred← citeshttps://doi.org/10.1007/s10238-025-01641-yopenalex-snapshotPD-L1 importance in malignancies comprehensive insights into the role of PD-L1 in malignancies: from molecular mechanisms to therapeutic opportunities
inferred← citeshttps://doi.org/10.1007/s10528-024-10796-4openalex-snapshotImpact of Doxorubicin and Docetaxel on Immune Checkpoint Expression in Colorectal Cancer: Insights into Chemotherapy Resistance Mechanisms
inferred← citeshttps://doi.org/10.1007/s12032-020-01372-yopenalex-snapshotPD-L1 upregulation accompanied with epithelial–mesenchymal transition attenuates sensitivity to ATR inhibition in p53 mutant pancreatic cancer cells
inferred← citeshttps://doi.org/10.1016/j.archoralbio.2024.106043openalex-snapshotBrusatol improves the efficacy of an anti-mouse-PD-1 antibody via inhibiting programmed cell death 1 ligand 1 expression in a murine head and neck squamous cell carcinoma model
inferred← citeshttps://doi.org/10.1016/j.bcp.2018.10.031openalex-snapshotEpithelial-mesenchymal transition: Initiation by cues from chronic inflammatory tumor microenvironment and termination by anti-inflammatory compounds and specialized pro-resolving lipids
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.112213openalex-snapshotA scoping review on the potentiality of PD-L1-inhibiting microRNAs in treating colorectal cancer: Toward single-cell sequencing-guided biocompatible-based delivery
inferred← citeshttps://doi.org/10.1016/j.ccell.2021.11.002openalex-snapshotThe allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1
inferred← citeshttps://doi.org/10.1016/j.clim.2021.108728openalex-snapshotAtezolizumab and blockade of LncRNA PVT1 attenuate cisplatin resistant ovarian cancer cells progression synergistically via JAK2/STAT3/PD-L1 pathway
inferred← citeshttps://doi.org/10.1016/j.cllc.2021.09.010openalex-snapshotDesign and Rationale for a Phase III, Double-Blind, Placebo-Controlled Study of Neoadjuvant Durvalumab + Chemotherapy Followed by Adjuvant Durvalumab for the Treatment of Patients With Resectable Stages II and III non-small-cell Lung Cancer: The AEGEAN Trial
inferred← citeshttps://doi.org/10.1016/j.cyto.2026.157177openalex-snapshotInnovative immune checkpoint modulators: monoclonal antibodies, small molecules, non-coding RNAs, and nanoparticles in cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.drudis.2025.104321openalex-snapshotEpigenetic code underlying EGFR-TKI resistance in non-small cell lung cancer: Elucidation of mechanisms and perspectives on therapeutic strategies
inferred← citeshttps://doi.org/10.1016/j.ebiom.2021.103542openalex-snapshotGenetic and immune characteristics of sentinel lymph node metastases and multiple lymph node metastases compared to their matched primary breast tumours
inferred← citeshttps://doi.org/10.1016/j.eclinm.2021.101134openalex-snapshotThe association between CD8+ tumor-infiltrating lymphocytes and the clinical outcome of cancer immunotherapy: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.ejca.2015.08.013openalex-snapshotProgrammed death-1 ligand 1 and 2 are highly expressed in pleomorphic carcinomas of the lung: Comparison of sarcomatous and carcinomatous areas
inferred← citeshttps://doi.org/10.1016/j.humpath.2018.03.025openalex-snapshotClinical implication of programmed cell death-1 ligand-1 expression in tonsillar squamous cell carcinoma in association with intratumoral heterogeneity, human papillomavirus, and epithelial-to-mesenchymal transition
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