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DNase II-dependent DNA digestion is required for DNA sensing by TLR9
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1521-4141(200107)31:7<2154::aid-immu2154>3.0.co;2-uopenalex-snapshot
Identification of CpG oligonucleotide sequences with high induction of IFN-α/β in plasmacytoid dendritic cells
inferredcites →https://doi.org/10.1002/eji.200323813openalex-snapshot
Rational design of new CpG oligonucleotides that combine B cell activation with high IFN‐α induction in plasmacytoid dendritic cells
inferredcites →https://doi.org/10.1002/eji.200323948openalex-snapshot
A minimal human immunostimulatory CpG motif that potently induces IFN‐γ and IFN‐α production
inferredcites →https://doi.org/10.1002/eji.200324032openalex-snapshot
Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities
inferredcites →https://doi.org/10.1002/embj.201386117openalex-snapshot
RNA:DNA hybrids are a novel molecular pattern sensed by TLR9
inferredcites →https://doi.org/10.1016/j.coi.2010.12.015openalex-snapshot
Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses
inferredcites →https://doi.org/10.1016/j.immuni.2011.11.018openalex-snapshot
Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
inferredcites →https://doi.org/10.1038/76032openalex-snapshot
Features of systemic lupus erythematosus in Dnase1-deficient mice
inferredcites →https://doi.org/10.1038/91070openalex-snapshot
Mutation of DNASE1 in people with systemic lupus erythematosus
inferredcites →https://doi.org/10.1038/nature03547openalex-snapshot
Spatiotemporal regulation of MyD88–IRF-7 signalling for robust type-I interferon induction
inferredcites →https://doi.org/10.1038/nature05245openalex-snapshot
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
inferredcites →https://doi.org/10.1038/nature06116openalex-snapshot
Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
inferredcites →https://doi.org/10.1038/ncomms2949openalex-snapshot
An essential role for the N-terminal fragment of Toll-like receptor 9 in DNA sensing
inferredcites →https://doi.org/10.1038/nri2587openalex-snapshot
A cell biological view of Toll-like receptor function: regulation through compartmentalization
inferredcites →https://doi.org/10.1042/bj20060564openalex-snapshot
Identification of three crucial histidine residues (His115, His132 and His297) in porcine deoxyribonuclease II
inferredcites →https://doi.org/10.1073/pnas.1215006109openalex-snapshot
STING manifests self DNA-dependent inflammatory disease
inferredcites →https://doi.org/10.1074/jbc.m410868200openalex-snapshot
Spontaneous Formation of Nucleic Acid-based Nanoparticles Is Responsible for High Interferon-α Induction by CpG-A in Plasmacytoid Dendritic Cells
inferredcites →https://doi.org/10.1084/jem.20041964openalex-snapshot
A type I interferon autocrine–paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells
inferredcites →https://doi.org/10.1084/jem.20050914openalex-snapshot
Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus
inferredcites →https://doi.org/10.1084/jem.20051654openalex-snapshot
Toll-like receptor–independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
inferredcites →https://doi.org/10.1084/jem.20060401openalex-snapshot
Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation
inferredcites →https://doi.org/10.1084/jem.20090480openalex-snapshot
Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8
inferredcites →https://doi.org/10.1126/science.1187029openalex-snapshot
Bifurcation of Toll-Like Receptor 9 Signaling by Adaptor Protein 3
inferredcites →https://doi.org/10.1146/annurev.immunol.20.100301.064842openalex-snapshot
CpG Motifs in Bacterial DNA and Their Immune Effects
inferredcites →https://doi.org/10.1371/journal.pone.0059148openalex-snapshot
Biogenesis and Proteolytic Processing of Lysosomal DNase II
inferredcites →https://doi.org/10.4049/jimmunol.1203162openalex-snapshot
Molecular Basis of DNA Recognition in the Immune System
inferredcites →https://doi.org/10.4049/jimmunol.1301419openalex-snapshot
Cutting Edge: DNA Sensing via the STING Adaptor in Myeloid Dendritic Cells Induces Potent Tolerogenic Responses
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Toward a structural understanding of nucleic acid‐sensing Toll‐like receptors in the innate immune system
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Quantitative Mapping of Endosomal DNA Processing by Single Molecule Counting
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Role of Interferon‐γ–Producing Th1 Cells in a Murine Model of Type I Interferon–Independent Autoinflammation Resulting From DN ase II Deficiency
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Intratumoral vidutolimod as monotherapy or in combination with pembrolizumab in patients with programmed cell death 1 blockade–resistant melanoma: Final analysis from a phase 1b study
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Molecular mechanisms of nonself nucleic acid recognition by the innate immune system
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Endosomal Toll-Like Receptors as Therapeutic Targets for Autoimmune Diseases
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Gold nanoparticles functionalized with Ru(II)bipyridyl labeled DNA as a luminescent probe for the sensitive determination of DNase I
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Photoaging: UV radiation-induced cGAS-STING signaling promotes the aging process in skin by remodeling the immune network
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inferred← citeshttps://doi.org/10.1007/s11926-026-01228-wopenalex-snapshot
Type I Interferonopathies: Fifteen Years On, From Concept to Therapeutic Perspectives
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Structural aspects of nucleic acid-sensing Toll-like receptors
inferred← citeshttps://doi.org/10.1016/b978-0-12-801968-9.00002-7openalex-snapshot
Homeostatic Inflammation as Environmental-Adaptation Strategy
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The Role of Nucleic Acid Sensing in Controlling Microbial and Autoimmune Disorders
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Ribosomal DNA instability: An evolutionary conserved fuel for inflammaging
inferred← citeshttps://doi.org/10.1016/j.cell.2019.11.001openalex-snapshot
TLR8 Is a Sensor of RNase T2 Degradation Products
inferred← citeshttps://doi.org/10.1016/j.cell.2020.02.041openalex-snapshot
Toll-like Receptors and the Control of Immunity
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ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA
inferred← citeshttps://doi.org/10.1016/j.coi.2016.10.003openalex-snapshot
Nucleic acid-sensing TLRs: trafficking and regulation
inferred← citeshttps://doi.org/10.1016/j.coi.2018.09.009openalex-snapshot
DNA as a self-antigen: nature and regulation
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Innate sensing of mRNA vaccines
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Bovine milk RNases modulate pro-inflammatory responses induced by nucleic acids in cultured immune and epithelial cells
inferred← citeshttps://doi.org/10.1016/j.ejpb.2016.07.001openalex-snapshot
Degradation and protection of DNAzymes on human skin
inferred← citeshttps://doi.org/10.1016/j.healun.2021.03.007openalex-snapshot
Cell-free DNA beyond a biomarker for rejection: Biological trigger of tissue injury and potential therapeutics
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.123438openalex-snapshot
Development of potent unmethylated CpG DNA hydrogel by introducing i-motifs into long single-stranded DNA
inferred← citeshttps://doi.org/10.1016/j.immuni.2016.04.002openalex-snapshot
Recognition of Endogenous Nucleic Acids by the Innate Immune System
inferred← citeshttps://doi.org/10.1016/j.immuni.2018.03.013openalex-snapshot
Toll-like Receptor 9 Contains Two DNA Binding Sites that Function Cooperatively to Promote Receptor Dimerization and Activation
inferred← citeshttps://doi.org/10.1016/j.immuni.2020.03.009openalex-snapshot
Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2
inferred← citeshttps://doi.org/10.1016/j.immuni.2020.06.014openalex-snapshot
Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids
inferred← citeshttps://doi.org/10.1016/j.immuni.2024.03.004openalex-snapshot
Decoding Toll-like receptors: Recent insights and perspectives in innate immunity
inferred← citeshttps://doi.org/10.1016/j.immuni.2024.04.010openalex-snapshot
Lysosomal endonuclease RNase T2 and PLD exonucleases cooperatively generate RNA ligands for TLR7 activation
inferred← citeshttps://doi.org/10.1016/j.it.2019.06.001openalex-snapshot
Self-DNA Sensing in Lung Inflammatory Diseases
inferred← citeshttps://doi.org/10.1016/j.it.2019.08.001openalex-snapshot
Guardians of the Cell: Effector-Triggered Immunity Steers Mammalian Immune Defense
inferred← citeshttps://doi.org/10.1016/j.jhep.2017.05.020openalex-snapshot
Free cholesterol accumulation in liver sinusoidal endothelial cells exacerbates acetaminophen hepatotoxicity via TLR9 signaling
inferred← citeshttps://doi.org/10.1016/j.jid.2016.05.122openalex-snapshot
The Exonuclease Trex2 Shapes Psoriatic Phenotype
inferred← citeshttps://doi.org/10.1016/j.jtha.2024.11.028openalex-snapshot
Therapeutic potential of DNases in immunothrombosis: promising succor or uncertain future?
inferred← citeshttps://doi.org/10.1016/j.medj.2025.100926openalex-snapshot
The comings and goings of cell-free DNA: Biological and clinical implications
inferred← citeshttps://doi.org/10.1016/j.mtbio.2024.101360openalex-snapshot
Treating acute lung injury through scavenging of cell-free DNA by cationic nanoparticles
inferred← citeshttps://doi.org/10.1016/j.omtn.2023.08.011openalex-snapshot
Characterization of cooperative PS-oligo activation of human TLR9
inferred← citeshttps://doi.org/10.1016/j.rechem.2024.101349openalex-snapshot
Discovery of PLD4 modulators by high-throughput screening and kinetic analysis
inferred← citeshttps://doi.org/10.1016/j.sbi.2017.05.010openalex-snapshot
Structural insights into ligand recognition and regulation of nucleic acid-sensing Toll-like receptors
inferred← citeshttps://doi.org/10.1016/j.snb.2023.133664openalex-snapshot
A supramolecular biosensor for monitoring lysosomal DNase activity in vivo and identifying tumor cells by responding to G-quadruplex hydrolysis
inferred← citeshttps://doi.org/10.1016/j.str.2024.02.019openalex-snapshot
Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4
inferred← citeshttps://doi.org/10.1016/j.talanta.2024.126538openalex-snapshot
Graphene oxide-functionalized molecular beacon for real-time interference-free detection of Ki-67 mRNA in living cells
inferred← citeshttps://doi.org/10.1016/j.vetpar.2020.109119openalex-snapshot
Comparative analysis of excretory–secretory products of muscle larvae of three isolates of Trichinella pseudospiralis by the iTRAQ method
inferred← citeshttps://doi.org/10.1016/j.ydbio.2017.06.028openalex-snapshot
Dnases in health and disease
inferred← citeshttps://doi.org/10.1016/j.ympev.2022.107554openalex-snapshot
Discovery of deoxyribonuclease II-like proteins in bacteria
inferred← citeshttps://doi.org/10.1016/j.ymthe.2025.07.029openalex-snapshot
Cell-selective telomere damage by thiopurine-based oligonucleotide for diffuse large B cell lymphoma immunotherapy
inferred← citeshttps://doi.org/10.1021/acsnano.1c11575openalex-snapshot
Controlling Nuclease Degradation of Wireframe DNA Origami with Minor Groove Binders
inferred← citeshttps://doi.org/10.1038/cdd.2016.87openalex-snapshot
Can the cargo control the car? Mitochondrial DNA as a stimulator of TLR9-mediated autophagosome–lysosome fusion
inferred← citeshttps://doi.org/10.1038/ncomms15363openalex-snapshot
Short single-stranded DNA degradation products augment the activation of Toll-like receptor 9
inferred← citeshttps://doi.org/10.1038/nri.2016.78openalex-snapshot
Discriminating self from non-self in nucleic acid sensing
inferred← citeshttps://doi.org/10.1038/nri3875openalex-snapshot
Translating nucleic acid-sensing pathways into therapies
inferred← citeshttps://doi.org/10.1038/s41392-020-00347-9openalex-snapshot
Targeting nuclear acid-mediated immunity in cancer immune checkpoint inhibitor therapies
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Cytosolic nucleic acid sensing as driver of critical illness: mechanisms and advances in therapy
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Downstream STING pathways IRF3 and NF-κB differentially regulate CCL22 in response to cytosolic dsDNA
inferred← citeshttps://doi.org/10.1038/s41467-018-03555-8openalex-snapshot
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells
inferred← citeshttps://doi.org/10.1038/s41467-021-26150-wopenalex-snapshot
Cleavage of DNA and RNA by PLD3 and PLD4 limits autoinflammatory triggering by multiple sensors
inferred← citeshttps://doi.org/10.1038/s41467-021-26880-xopenalex-snapshot
Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy
inferred← citeshttps://doi.org/10.1038/s41467-022-30654-4openalex-snapshot
Macrophages disseminate pathogen associated molecular patterns through the direct extracellular release of the soluble content of their phagolysosomes
inferred← citeshttps://doi.org/10.1038/s41467-022-35732-1openalex-snapshot
Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation
inferred← citeshttps://doi.org/10.1038/s41577-021-00577-0openalex-snapshot
Regulation of the nucleic acid-sensing Toll-like receptors
inferred← citeshttps://doi.org/10.1038/s41584-024-01184-8openalex-snapshot
Emerging concepts and treatments in autoinflammatory interferonopathies and monogenic systemic lupus erythematosus
inferred← citeshttps://doi.org/10.1038/s41586-019-1611-7openalex-snapshot
Release from UNC93B1 reinforces the compartmentalized activation of select TLRs
inferred← citeshttps://doi.org/10.1038/s41590-018-0179-yopenalex-snapshot
PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing
inferred← citeshttps://doi.org/10.1038/s41590-024-01966-yopenalex-snapshot
DNA-sensing pathways in health, autoinflammatory and autoimmune diseases
inferred← citeshttps://doi.org/10.1038/s41598-017-12308-4openalex-snapshot
Double deficiency of Trex2 and DNase1L2 nucleases leads to accumulation of DNA in lingual cornifying keratinocytes without activating inflammatory responses
inferred← citeshttps://doi.org/10.1038/s41598-017-15178-yopenalex-snapshot
Phosphodiester backbone of the CpG motif within immunostimulatory oligodeoxynucleotides augments activation of Toll-like receptor 9
inferred← citeshttps://doi.org/10.1039/c7ra13293jopenalex-snapshot
CpG incorporated DNA microparticles for elevated immune stimulation for antigen presenting cells
inferred← citeshttps://doi.org/10.1074/jbc.ra120.015867openalex-snapshot
Quantification and characterization of the 5′ exonuclease activity of the lysosomal nuclease PLD3 by a novel cell-based assay
inferred← citeshttps://doi.org/10.1084/jem.20221086openalex-snapshot
Secreted mammalian DNases protect against systemic bacterial infection by digesting biofilms
inferred← citeshttps://doi.org/10.1084/jem.20230341openalex-snapshot
Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage
inferred← citeshttps://doi.org/10.1093/intimm/dxab033openalex-snapshot
Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages
inferred← citeshttps://doi.org/10.1093/intimm/dxab037openalex-snapshot
Dynamic control of nucleic-acid-sensing Toll-like receptors by the endosomal compartment
inferred← citeshttps://doi.org/10.1093/intimm/dxae052openalex-snapshot
Mechanisms and effects of activation of innate immunity by mitochondrial nucleic acids
inferred← citeshttps://doi.org/10.1093/intimm/dxy016openalex-snapshot
Mechanisms controlling nucleic acid-sensing Toll-like receptors
inferred← citeshttps://doi.org/10.1093/jb/mvaf011openalex-snapshot
Innate immune responses to lysosomal nucleic acid stress
inferred← citeshttps://doi.org/10.1093/jimmun/vkaf080openalex-snapshot
CXCL14 is an essential modulator of TLR9 agonist–induced antitumor immune responses
inferred← citeshttps://doi.org/10.1093/nar/gkac618openalex-snapshot
Insights into innate immune activation via PS-ASO–protein–TLR9 interactions
inferred← citeshttps://doi.org/10.1093/nar/gkaf1302openalex-snapshot
The lysosomal catabolism of nucleic acids—critical regulators of the innate immune system
inferred← citeshttps://doi.org/10.1093/nar/gkx222openalex-snapshot
Structure of acid deoxyribonuclease
inferred← citeshttps://doi.org/10.1101/2022.03.08.483519openalex-snapshot
Interferon regulatory factor 3 upregulates the Treg recruitment factor CCL22 in response to double-stranded DNA in cancer cells
inferred← citeshttps://doi.org/10.1101/2024.07.10.602775openalex-snapshot
IFNγ initiates TLR9-dependent autoimmune hepatitis in DNase II deficient mice
inferred← citeshttps://doi.org/10.1101/2025.10.14.682277openalex-snapshot
Murine Toll-like receptor 8 is a nucleic acid multi-sensor detecting 2’,3’-cyclic monophosphate guanosine as well as combinations of ribo-, deoxy-, cyclic nucleotides, and nucleosides
inferred← citeshttps://doi.org/10.1111/imm.13884openalex-snapshot
Nucleases: From Primitive Immune Defenders to Modern Biotechnology Tools
inferred← citeshttps://doi.org/10.1111/imr.12375openalex-snapshot
Nucleic acid‐sensing TLR s and autoimmunity: novel insights from structural and cell biology
inferred← citeshttps://doi.org/10.1111/imr.12537openalex-snapshot
The many ways tissue phagocytes respond to dying cells
inferred← citeshttps://doi.org/10.1124/pharmrev.123.000815openalex-snapshot
Targeting the Liver with Nucleic Acid Therapeutics for the Treatment of Systemic Diseases of Liver Origin
inferred← citeshttps://doi.org/10.1136/jitc-2025-012165openalex-snapshot
New insights into the role of IFN-α/β and TLR7/8/9 in cancer immunotherapy and systemic autoimmunity
inferred← citeshttps://doi.org/10.1146/annurev-biochem-032620-104401openalex-snapshot
Mitochondrial DNA Release in Innate Immune Signaling
inferred← citeshttps://doi.org/10.1146/annurev-immunol-042718-041257openalex-snapshot
Self-Awareness: Nucleic Acid–Driven Inflammation and the Type I Interferonopathies
inferred← citeshttps://doi.org/10.1158/2159-8290.cd-21-0425openalex-snapshot
Overcoming PD-1 Blockade Resistance with CpG-A Toll-Like Receptor 9 Agonist Vidutolimod in Patients with Metastatic Melanoma
inferred← citeshttps://doi.org/10.1186/s12929-025-01151-9openalex-snapshot
Involvement of nucleic acid-sensing toll-like receptors in human diseases and their controlling mechanisms
inferred← citeshttps://doi.org/10.1186/s12974-025-03333-6openalex-snapshot
Microglial double stranded DNA accumulation induced by DNase II deficiency drives neuroinflammation and neurodegeneration
inferred← citeshttps://doi.org/10.1186/s12974-025-03363-0openalex-snapshot
Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders
inferred← citeshttps://doi.org/10.1186/s40035-024-00427-8openalex-snapshot
Neuronal double-stranded DNA accumulation induced by DNase II deficiency drives tau phosphorylation and neurodegeneration
inferred← citeshttps://doi.org/10.1186/s41232-018-0068-7openalex-snapshot
New application of anti-TLR monoclonal antibodies: detection, inhibition and protection
inferred← citeshttps://doi.org/10.1189/jlb.3mr0316-115ropenalex-snapshot
Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?
inferred← citeshttps://doi.org/10.1189/jlb.4mr0316-108ropenalex-snapshot
Emerging roles of the processing of nucleic acids and Toll-like receptors in innate immune responses to nucleic acids
inferred← citeshttps://doi.org/10.12688/f1000research.10397.1openalex-snapshot
Advances in the understanding of mitochondrial DNA as a pathogenic factor in inflammatory diseases
inferred← citeshttps://doi.org/10.1371/journal.ppat.1006527openalex-snapshot
B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway
inferred← citeshttps://doi.org/10.1513/annalsats.201706-438mgopenalex-snapshot
Pharmacologic Protection of Mitochondrial DNA Integrity May Afford a New Strategy for Suppressing Lung Ischemia-Reperfusion Injury
inferred← citeshttps://doi.org/10.21203/rs.3.rs-7634140/v1openalex-snapshot
Cytosolic mtDNA and associated EYA-mediated pro-inflammatory signaling modulate healthspan in Drosophila
inferred← citeshttps://doi.org/10.2174/1389203720666190830162149openalex-snapshot
Single Stranded DNA Immune Modulators with Unmethylated CpG Motifs: Structure and Molecular Recognition by Toll-Like Receptor 9
inferred← citeshttps://doi.org/10.26508/lsa.202000809openalex-snapshot
Reduced RNA turnover as a driver of cellular senescence
inferred← citeshttps://doi.org/10.3389/fimmu.2018.01278openalex-snapshot
Insights Gained From the Study of Pediatric Systemic Lupus Erythematosus
inferred← citeshttps://doi.org/10.3389/fimmu.2019.02181openalex-snapshot
Bacterial RNA Contributes to the Down-Modulation of MHC-II Expression on Monocytes/Macrophages Diminishing CD4+ T Cell Responses
inferred← citeshttps://doi.org/10.3389/fimmu.2021.629922openalex-snapshot
The Role of Nucleases and Nucleic Acid Editing Enzymes in the Regulation of Self-Nucleic Acid Sensing
inferred← citeshttps://doi.org/10.3389/fimmu.2021.803090openalex-snapshot
S-540956, a CpG Oligonucleotide Annealed to a Complementary Strand With an Amphiphilic Chain Unit, Acts as a Potent Cancer Vaccine Adjuvant by Targeting Draining Lymph Nodes
inferred← citeshttps://doi.org/10.3389/fimmu.2022.941931openalex-snapshot
Nucleic Acid Sensing by Toll-Like Receptors in the Endosomal Compartment
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1695754openalex-snapshot
TIR domain proteins: regulatory mechanisms in the tumor immune microenvironment, clinical translation strategies, and prospects for precision therapy applications
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1802432openalex-snapshot
TLR7 and TLR9 have overlapping but distinct roles in systemic lupus erythematosus and Sjögren’s disease
inferred← citeshttps://doi.org/10.3389/fmicb.2022.845625openalex-snapshot
The Emerging Role of RNA Modifications in the Regulation of Antiviral Innate Immunity
inferred← citeshttps://doi.org/10.3389/fonc.2020.581107openalex-snapshot
Targeting Tumor-Associated Macrophages in the Pediatric Sarcoma Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/biom10071036openalex-snapshot
Deoxyribonucleases and Their Applications in Biomedicine
inferred← citeshttps://doi.org/10.3390/cancers15051619openalex-snapshot
DNA Repair Deficiency Regulates Immunity Response in Cancers: Molecular Mechanism and Approaches for Combining Immunotherapy
inferred← citeshttps://doi.org/10.3390/cancers18183006openalex-snapshot
Basophil Extracellular Traps in Immunity and Disease
inferred← citeshttps://doi.org/10.3390/genes10020092openalex-snapshot
RNA Modifications Modulate Activation of Innate Toll-Like Receptors
inferred← citeshttps://doi.org/10.4049/jimmunol.1500530openalex-snapshot
Bacterial RNA: An Underestimated Stimulus for Innate Immune Responses
inferred← citeshttps://doi.org/10.4049/jimmunol.1500600openalex-snapshot
Species-Specific Minimal Sequence Motif for Oligodeoxyribonucleotides Activating Mouse TLR9
inferred← citeshttps://doi.org/10.4049/jimmunol.1502130openalex-snapshot
Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II−/−IFNaR−/− Mice
inferred← citeshttps://doi.org/10.4049/jimmunol.1600757openalex-snapshot
Selectivity of Human TLR9 for Double CpG Motifs and Implications for the Recognition of Genomic DNA
inferred← citeshttps://doi.org/10.4049/jimmunol.1800159openalex-snapshot
Intra- and Extracellular Degradation of Neutrophil Extracellular Traps by Macrophages and Dendritic Cells
inferred← citeshttps://doi.org/10.4049/jimmunol.1900742openalex-snapshot
Antibody Opsonization of a TLR9 Agonist–Containing Virus-like Particle Enhances In Situ Immunization
inferred← citeshttps://doi.org/10.6084/m9.figshare.26488356openalex-snapshot
Additional file 1 of Neuronal double-stranded DNA accumulation induced by DNase II deficiency drives tau phosphorylation and neurodegeneration
inferred← citeshttps://doi.org/10.64898/2026.04.29.720527openalex-snapshot
Defining the Immunomodulatory Determinants of 3-mer Oligonucleotides on TLR7 and TLR8 sensing
inferred← citeshttps://doi.org/10.64898/2026.09.25.754422openalex-snapshot
Macrophage-derived IL-27 sustains autoreactive CD8 + cytotoxic T cells in autoimmune hepatitis
inferred← citeshttps://doi.org/10.70675/0b7bdb5azf42fz42d0z856dz67e069b5b290openalex-snapshot
Détection de l'ADN circulant chez le sujet sain et le patient atteint d'un cancer métastatique par PCR digitale en gouttelettes
inferred← citeshttps://doi.org/10.70675/108bf267z8a2az4f46zbdd5z93af4b9baec8openalex-snapshot
Etude du TLR9 à la membrane plasmique des lymphocytes B : caractérisation des anticorps anti-TLR9 commerciaux
inferred← citeshttps://doi.org/10.70675/154b0002zc293z47a9z8bfbz9909e15c15e6openalex-snapshot
Il-26 : une cytokine pro-inflammatoire stimulant les cellules immunitaires innées myéloïdes
inferred← citeshttps://doi.org/10.70675/2af1f0cfz45caz418azb93ez88367c4a54c8openalex-snapshot
Étude de la fonction de la DNASE1L3 en contexte auto-immun et anti-tumoral
inferred← citeshttps://doi.org/10.70675/625f8f0fz08b0z42c4za392z06860a6892c1openalex-snapshot
Deregulation of TLR9 signalling pathway in human keratinocytes by E6 and E7 oncoproteins from beta human papillomavirus type 38
inferred← citeshttps://doi.org/10.70962/jhi.20260015openalex-snapshot
Adenosine deaminase type 2 deficiency: From rare to common
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